Genome History

2R Hypothesis

Whole genome duplication hypothesis or 2R hypothesis

Circos

PAHG

Phylogenomic Analysis of Human Genome

Human Paralogons

Species Employed

Piecemeal Theory

Diagram representing the Piecemeal theory of gene duplication

PAHG has been integrated into CNCB/NGDC China, BIG Search Engine: https://ngdc.cncb.ac.cn/search/specific?db=pahg&q=, and listed as a partner database of NGDC at https://ngdc.cncb.ac.cn/partners.

Other Human Multi gene Family

Importance of HOX Paralogon in evolutionary, developmental and phylogenomic studies

Duplication history of gene families located on HOX cluster bearing chromosomes

Evolutionary importance of FGFR Paralogon

Evolutionary history of gene families shaping the current architecture of HSA 4/5/8/10

Phylogenomic importance of linkage groups located on human chromosomes 1, 2, 8 and 20

Duplication history of HSA 1/2/8/20 Paralogon

Paralogons History

Graph showing paralogon-wise distribution of duplication numbers

Gene Search
Family Search

Duplication History

Graph showing cladogenesis-wise distribution of duplication numbers

HOX Paralogon

Hsa:2/7/12/17

FGFR Paralogon

Hsa:4/5/8/10

HSA:1/2/8/20

MHC Paralogon

Hsa:1/6/9/19

Paralogy Regions

Phylogenomic Analysis

Age Estimates of Duplications

Co-duplication Events

The database provides an insight into the evolutionary history of human multigene families.