Table: Families analysed for 1/2/8/20 paralogon

List of human gene families inhabiting Human Chromosomes 1/2/8/20 which were used in the phylogenetic analysis of 1/2/8/20 paralogon. Please click on particular family to view its members.

Name	Year	Number of Included Taxa	Function	Number of Sequences Included
EYA transcriptional coactivator and phosphatases (EYA)	2011	19	Metal ion binding, Hydrolase activity, Protein tyrosine phosphatase activity, Protein binding, Chromatin binding	62
Src family tyrosine kinases subfamily B (SrcB)	2011	23	Nucleotide binding, ATP binding, Transferase activity, Protein tyrosine kinase activity, Protein binding	62
Lysosomal transmembrane protein (LAPTM)	2011	27	Transport, Protein binding	62
Matrilins (MATN)	2011	14	Extracellular matrix structural constituent, Protein binding	46
MYB family of transcription factor genes (MYB)	2011	18	Sequence-specific DNA binding transcription factor activity,DNA, Protein binding	55
Myc proto-oncogene protein (MYC)	2011	20	Sequence-specific DNA binding transcription factor activity, Protein binding	53
Potassium voltage-gated channel delayed-rectifier, subfamily S (KCNS)	2011	26	Voltage-gated ion channel activity, Protein binding, Potassium channel regulator and delayed-rectifier activity	60
Protein tyrosine phosphatases receptor type subfamily 1 (PTPR)	2011	17	Protein tyrosine phosphatase activity, Hydrolase activity, Receptor activity, Protein binding	59
Src family tyrosine kinases subfamily A (SrcA)	2011	21	Protein tyrosine kinase activity, ATP binding, Transferase activity, Nucleotide binding, Protein binding	67
Syndecans (SDC)	2011	14	Cytoskeletal protein binding, Glycoprotein binding, Protein C-terminus binding, PDZ domain binding	46
WNT1 inducible signaling pathway (WISP)/(CCN)	2011	25	Protein binding, Insulin-like growth factor binding, Growth factor activity	63
DLG associated proteins (DLGAP)	2017	25	Protein binding activity	85
E2F transcription factors (E2F)	2017	31	DNA binding, Protein binding, Sequence-specific DNA binding transcription factor activity, Transcription factor binding	84
Family with Sequence Similarity 110 (FAM110)	2017	25	Alpha-tubulin binding,Protein binding	56
Grainyhead like Transcription factor (GRHL)/(TFCP2)	2017	26	Chromatin DNA binding, Sequence-specific DNA binding, Protein binding.	57
Inhibitor of DNA binding proteins (ID)	2017	35	Sequence-specific DNA binding transcription factor activity, Protein binding, Protein dimerization activity	65
Maestro heat-like repeat-containing (MROH)	2017	22	Protein binding	46
Zinc fingers C2H2C-type (MYT)	2017	22	Zinc ion binding,Sequence-specific DNA binding transcription factor activity	48
Nuclear Receptor Coactivator (NCOA)	2017	22	Protein dimerization activity,Chromatin binding,Nuclear hormone receptor binding,RNA polymerase II regulatory region DNA binding	54
Na+/K+ transporting ATPase interacting (NKAIN)	2017	24	Involves in ATPase binding	46
Potassium Voltage-Gated Channel subfamily Q (KCNQ)	2017	28	Voltage-gated potassium channel activity,Ankyrin binding,Delayed rectifier potassium channel activity	67
Regulators of G-protein signaling subfamily 3 (RGS)	2017	31	GTPase activator activity,Calmodulin binding,Protein binding	101
Regulating synaptic membrane exocytosis family (RIMS)	2017	27	Ion channel binding,Protein heterodimerization activity,Rab GTPase binding	49
R-spondin family (RSPO)	2017	31	Heparin binding, G-protein coupled receptor binding, Protein binding, Receptor binding	60
Solute carrier family 30 (SLC30)	2017	23	Zinc ion transmembrane transporter activity, Protein binding, Cation transmembrane transporter activity	74
Syntrophins (SNT)	2017	28	Actin binding, PDZ domain binding, Calmodulin binding,	81
Sorting nexins subfamily 2 (SNX)	2017	29	Protein binding,Phosphatidylinositol binding	43
Stathmins (STMN)	2017	22	Tubulin binding,Protein domain specific binding,Signal transducer activity	63
Serine/Threonine-Protein Kinases (STK)	2017	25	ATP binding, Protein homodimerization activity, Protein serine/threonine kinase activity,Protein binding	72
Transcription Elongation factor A (SII) Proteins (TCEA)	2017	22	Zinc ion binding,DNA binding,Protein binding	51
UBX domain containing (UBXN)	2017	22	Ubiquitin binding,Protein phosphatase type 1 regulator activity,Protein binding	25
XK related family (XKR)	2017	24	Promotes phosphatidylserine exposure on apoptotic cell surface	101
YTH domain containing N6-methyladenosine readers subfamily F (YTHF)	2017	24	Poly(A) RNA binding, N6-methyladenosine-containing RNA binding	50
Antizyme Inhibitor (AZIN)/(ODC)	2017	25	Protein binding, Ornithine decarboxylase activator activity	55
Cholinergic receptors nicotinic subunits (CHRN)	2017	32	Drug binding,Ion channel activity,Acetylcholine receptor activity	123
Ciliary Rootlet Coiled-Coil Proteins (CROCC)	2017	28	Protein binding activity	42