Table: Duplication Summary

Summary of the phylogenetic analysis of gene families whose three or more members are residing on human paralogon HSA 1/2/8/20
For each gene family the chromosomal location and topologies (in the Newick format) of those genes are given, which arose through duplications after the invertebrates vertebrates split and before the tetrapod-fish divergence. The percentage bootstrap support of the internal branches is given with each relevant topology.
  • a Indicates that the gene family member is positioned on a different chromosome, i.e. Hsa6.
  • b Indicates that the gene family member is positioned on a different chromosome, i.e. Hsa18.
Family Name Hsa1 Hsa2/6a Hsa8/18 Hsa20 Topology
EYA EYA3 EYA4a EYA1 EYA2 (((6, 8) 20) 1) 99,76
HCK LCK - LYN , BLK HCK ((8,20) (8,1)) 98,85
LAPTM - LAPTM4A LAPTM4B - (2, 8) 94
MATN MATN1 MATN3 MATN2 MATN4 ((8, 20) (2,1)) 74
MYB - MYBa MYBL1 - (6, 8)
MYC MYCL1 MYCN MYC - ((1, 2) 8)) 59,99
KCNS - KCNS3 KCNS2 KCNS1 ((20,8)2) 99,97
PTPR PTPRU PTPRKa PTPRMb PTPR3 (((18, 20) 6) 1) 94,99
SRC FGR FYNa YES1b SRC (((6, 1)18) 20) 51,96,99
WISP - WISP3a WISP1 - (8,6) 79

Hsa: Homo Sapien Autosome.