>Homo sapiens_PKD1(ENSP_262304)
MPPAAPARLALALGLGLWLGALAGGPGRGCGPCEPPCLCGPAPGAACRVNCSGRGLRTLG
PALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEI
NLSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGCGEEY
VACLPDNSSGTVAAVSFSAAHEGLLQPEACSAFCFSTGQGLAALSEQGWCLCGAAQPSSA
SFACLSLCSGPPPPPAPTCRGPTLLQHVFPASPGATLVGPHGPLASGQLAAFHIAAPLPV
TATRWDFGDGSAEVDAAGPAASHRYVLPGRYHVTAVLALGAGSALLGTDVQVEAAPAALE
LVCPSSVQSDESLDLSIQNRGGSGLEAAYSIVALGEEPARAVHPLCPSDTEIFPGNGHCY
RLVVEKAAWLQAQEQCQAWAGAALAMVDSPAVQRFLVSRVTRSLDVWIGFSTVQGVEVGP
APQGEAFSLESCQNWLPGEPHPATAEHCVRLGPTGWCNTDLCSAPHSYVCELQPGGPVQD
AENLLVGAPSGDLQGPLTPLAQQDGLSAPHEPVEVMVFPGLRLSREAFLTTAEFGTQELR
RPAQLRLQVYRLLSTAGTPENGSEPESRSPDNRTQLAPACMPGGRWCPGANICLPLDASC
HPQACANGCTSGPGLPGAPYALWREFLFSVPAGPPAQYSVTLHGQDVLMLPGDLVGLQHD
AGPGALLHCSPAPGHPGPRAPYLSANASSWLPHLPAQLEGTWACPACALRLLAATEQLTV
LLGLRPNPGLRLPGRYEVRAEVGNGVSRHNLSCSFDVVSPVAGLRVIYPAPRDGRLYVPT
NGSALVLQVDSGANATATARWPGGSVSARFENVCPALVATFVPGCPWETNDTLFSVVALP
WLSEGEHVVDVVVENSASRANLSLRVTAEEPICGLRATPSPEARVLQGVLVRYSPVVEAG
SDMVFRWTINDKQSLTFQNVVFNVIYQSAAVFKLSLTASNHVSNVTVNYNVTVERMNRMQ
GLQVSTVPAVLSPNATLALTAGVLVDSAVEVAFLWTFGDGEQALHQFQPPYNESFPVPDP
SVAQVLVEHNVMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPSVAVGVSDGVLVA
GRPVTFYPHPLPSPGGVLYTWDFGDGSPVLTQSQPAANHTYASRGTYHVRLEVNNTVSGA
AAQADVRVFEELRGLSVDMSLAVEQGAPVVVSAAVQTGDNITWTFDMGDGTVLSGPEATV
EHVYLRAQNCTVTVGAASPAGHLARSLHVLVFVLEVLRVEPAACIPTQPDARLTAYVTGN
PAHYLFDWTFGDGSSNTTVRGCPTVTHNFTRSGTFPLALVLSSRVNRAHYFTSICVEPEV
GNVTLQPERQFVQLGDEAWLVACAWPPFPYRYTWDFGTEEAAPTRARGPEVTFIYRDPGS
YLVTVTASNNISAANDSALVEVQEPVLVTSIKVNGSLGLELQQPYLFSAVGRGRPASYLW
DLGDGGWLEGPEVTHAYNSTGDFTVRVAGWNEVSRSEAWLNVTVKRRVRGLVVNASRTVV
PLNGSVSFSTSLEAGSDVRYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSA
QDSIFVYVLQLIEGLQVVGGGRYFPTNHTVQLQAVVRDGTNVSYSWTAWRDRGPALAGSG
KGFSLTVLEAGTYHVQLRATNMLGSAWADCTMDFVEPVGWLMVAASPNPAAVNTSVTLSA
ELAGGSGVVYTWSLEEGLSWETSEPFTTHSFPTPGLHLVTMTAGNPLGSANATVEVDVQV
PVSGLSIRASEPGGSFVAAGSSVPFWGQLATGTNVSWCWAVPGGSSKRGPHVTMVFPDAG
TFSIRLNASNAVSWVSATYNLTAEEPIVGLVLWASSKVVAPGQLVHFQILLAAGSAVTFR
LQVGGANPEVLPGPRFSHSFPRVGDHVVSVRGKNHVSWAQAQVRIVVLEAVSGLQVPNCC
EPGIATGTERNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIQV
RAFNALGSENRTLVLEVQDAVQYVALQSGPCFTNRSAQFEAATSPSPRRVAYHWDFGDGS
PGQDTDEPRAEHSYLRPGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDVVLPLQVL
MRRSQRNYLEAHVDLRDCVTYQTEYRWEVYRTASCQRPGRPARVALPGVDVSRPRLVLPR
LALPVGHYCFVFVVSFGDTPLTQSIQANVTVAPERLVPIIEGGSYRVWSDTRDLVLDGSE
SYDPNLEDGDQTPLSFHWACVASTQREAGGCALNFGPRGSSTVTIPRERLAAGVEYTFSL
TVWKAGRKEEATNQTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGRCLNCSSGS
KRGRWAARTFSNKTLVLDETTTSTGSAGMRLVLRRGVLRDGEGYTFTLTVLGRSGEEEGC
ASIRLSPNRPPLGGSCRLFPLGAVHALTTKVHFECTGWHDAEDAGAPLVYALLLRRCRQG
HCEEFCVYKGSLSSYGAVLPPGFRPHFEVGLAVVVQDQLGAAVVALNRSLAITLPEPNGS
ATGLTVWLHGLTASVLPGLLRQADPQHVIEYSLALVTVLNEYERALDVAAEPKHERQHRA
QIRKNITETLVSLRVHTVDDIQQIAAALAQCMGPSRELVCRSCLKQTLHKLEAMMLILQA
ETTAGTVTPTAIGDSILNITGDLIHLASSDVRAPQPSELGAESPSRMVASQAYNLTSALM
RILMRSRVLNEEPLTLAGEEIVAQGKRSDPRSLLCYGGAPGPGCHFSIPEAFSGALANLS
DVVQLIFLVDSNPFPFGYISNYTVSTKVASMAFQTQAGAQIPIERLASERAITVKVPNNS
DWAARGHRSSANSANSVVVQPQASVGAVVTLDSSNPAAGLHLQLNYTLLDGHYLSEEPEP
YLAVYLHSEPRPNEHNCSASRRIRPESLQGADHRPYTFFISPGSRDPAGSYHLNLSSHFR
WSALQVSVGLYTSLCQYFSEEDMVWRTEGLLPLEETSPRQAVCLTRHLTAFGASLFVPPS
HVRFVFPEPTADVNYIVMLTCAVCLVTYMVMAAILHKLDQLDASRGRAIPFCGQRGRFKY
EILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRAFHRNSLDIFRIATPHSLGSVW
KIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDA
ALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYG
AVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPA
GQQVLDIDSCLDSSVLDSSFLTFSGLHAEQAFVGQMKSDLFLDDSKSLVCWPSGEGTLSW
PDLLSDPSIVGSNLRQLARGQAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEG
VSSPAPTQDTHMETDLLSSLSSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTG
LVEGLRKRLLPAWCASLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASF
LGWEPLKVLLEALYFSLVAKRLHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLAKEE
ARKVKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRS
EELWPWMAHVLLPYVHGNQSSPELGPPRLRQVRLQEALYPDPPGPRVHTCSAAGGFSTSD
YDVGWESPHNGSGTWAYSAPDLLGAWSWGSCAVYDSGGYVQELGLSLEESRDRLRFLQLH
NWLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALRRLSAGLSLP
LLTSVCLLLFAVHFAVAEARTWHREGRWRVLRLGAWARWLLVALTAATALVRLAQLGAAD
RQWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLC
RALPELLGVTLGLVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESW
HLSPLLCVGLWALRLWGALRLGAVILRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLW
MGLSKVKEFRHKVRFEGMEPLPSRSSRGSKVSPDVPPPSAGSDASHPSTSSSQLDGLSVS
LGRLGTRCEPEPSRLQAVFEALLTQFDRLNQATEDVYQLEQQLHSLQGRRSSRAPAGSSR
GPSPGLRPALPSRLARASRGVDLATGPSRTPLRAKNKVHPSST

>Gorilla gorilla_PKD1(ENSGGOP_6875)
MPPAAPVRLALALGLGLWLGALAGGPGRGCGPCEPPCLCGPAPGAACRVNCSGRGLRTLG
PALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEI
NLSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGCGEEY
VACLPDNSSGTVAAVSFSAAHEGLLQPEACSAFCFSTGQGLAALSEQGWCLCGAAQPSSA
SFACLSCSSPPPPPAPTCRGRTLLQHVFPASPGAALVGPHGPLASGRLAAFHIAAPLPVT
ATRWDFGDGSPEVDAAGPAASHRYVLPGRYHVTAVLALGAGSALLGTDVQVEAAPATLEL
VCPSSVQSDESLDLSIRNRGGSGLEAAYSIVALGEEPARAVHPLCPSDTEIFPGSGHCYR
LVVEKAAWLQAQEQCRAWAGAALAMVDSPAVQRFLVSRVTRSLDVWIGFSTVQGVEVGPA
PQGEAFSLESCQNWLPGEPHPATAEHCVRLGPTGWCNTDLCSAPHSYVCELRPGGPVQDA
ENLLVGAPSGDLQGPLTPLAQQDGLSAPHEPVEVMVFPGLRLSREAFLTTAEFGTQELRR
PAQLRLQVYRLLSTAGTPENGSEPESRSPDNRTQLVPACMPGGCWCPGANICLPLDASCH
PQACANGCTSGPGLPGAPYALWREFLFSVPAGPPAQYSVTLHGQDVLMLPGDLVGLQHDA
GPSALLHCSPAPSHPGPQAPYLSANASSWLPHLPAQLEGTWACPACALRLLAATEQLTVL
LGLRPNPGLRLPGRYEVRAEVGNGVSRHNLSCSFDVVSPVAGLRVIYPAPHHGRLYVPTN
GSALVLQVDSGANATATARWPGGSVSARFENACPALVATFVPGCPWETNDTLFSAVALPW
LSEGEHVMDVVVENSASRANLSLRVTAEEPICGLRATPSPEARVLQGVLVRYSPVVEAGS
DMVFRWTINDKQSLTFQNVVFNVIQSAAVFKLSLTASNHVSNVTVNYNVTVERMNRMQGL
RVSTVPAVLSPNATLALTAGVLVDSAVEVAFLWTFGDGEQALHQFQPPYNESFPVPDPSV
AQVLVEHNVTHTYAAPGEYILTVLASNAFENLTQQVPVSVRTSLPSVAVGVSDGVLVAGR
PVTFYPHPLPSPGGVLYTWDFGDGSPVLTQSQPAANHTYASRGTYHVRLEVNNTVSGAAA
QADVRVFEELRGLSVDMSLAVEQGAPVVVSAAVQTGDNITWTFDMGDGTVLSGPEATVEH
VYLRAQNCTVTVGAASPAGHLAQSLHVLVFVLEVLRIEPAACIPTQPHARLTAYVTGNPA
HYLFDWTFGDGSSNTTVRGCPTVTHNFTRSGTFPLALVLSSRVNRAHYFTSICVEPEVGN
VTLQPERQFVQLGDEARLVACAWPPFPYRYTWDFGTEEAGPARAGGPEVTCIYRDPGSYL
VTVTASNNISAANDSALVEVQEPVLVTSIKVNGSLGLELQQPYLFSVVGRGRPASYVWDL
GDGGRLEGPEVTHAYNSTGDFTVRVAGWNEVSHSEAWLNVTVKRRVRGLVVNASRTVVPL
NGSVSFSTSLEAGSDVRYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSAQD
SIFVYVLQLIEGLQVVGGGRYFPTNHTVQLQAVVRDGTNISYSWTAWRDRGPALAGSGKG
FSLTALEAGTYHVRLRATNMLGSAWADCTVDFVEPVGWLMVAASPNPAAVNTSVTLCAEL
AGGSGVVYTWSLEEGLSWETTEPFTTHSFPTPGLHLVTMTAGNPLGSANATMEVDVQVPV
SGLSIRASEPGGSFVAAGSSVPFWGQLATGTNVSWCWVVPGGSSKRGPHVTMVFPDAGTF
SIRLNASNAVSWVSATYNLTVEEPIVGLVLWASSKVVAPGQPVHFQILLAAGSAVTFRLQ
VGGASPEVLPGPRFSHSFPRVGDHVVSVQGKNHVSWAQAQVRIVVLEAVSGLQVPNCCES
GIATGTERNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIQVRA
FNALGSENRTLVLEVQDAVQYVALRSGPCFTNRSAQFEATTSPSPRRVAYHWDFGDGSPG
QDTDEPRAEHSYLRPGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDVVLPLQVLMR
RSQRNYLEAHVDLRDCVTYQTEYRWEVYRTASCQRPGRPARVALPGVDVSRPQLVLPRLA
LPVGHYCFVFVVSFGDTPLARSIQANVTVAPERLVPIIEGGSYRVWSDTQDLVLDGSESY
DPNLEDGDQTPLSFHWACVASTQREAGGCALNFGPRGSSTVTIPRERLAAGVEYTFSLTV
WKAGRKEEATNQTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGRCLNCSSGSKR
GRWAARTFSNKTLVLDETTTSTGSAGMRLVLRRGVLRDGEGYTFTLSVLGRSGEEEGCAS
IRLSPNRPPLGGSCRLFPLGAVHALTTKVHFECTGWYDAEDAGAPLVYALLLRRCRQGHC
EEFCVYKGSLSSYEAVLPPGFRPHFEVGLAVVVQDQLGAAVVALNRSLAITLPEPNGSAT
GLTVWLHGLTASVLPGLLRQANPQHVIEYSLALVTVLNEYEQALEVAAEPKHERQRRAQI
RKNITETLVSLRVHTVDDIQQIAAALAQCMTRDPAGSYHLNLSSHFRWSALEVSVGLYTS
LCQYFSEEDVVWRTEALLPLEETSPRQAVCLTRHLTAFGASLFVPRSHVRFVFPEPTVDV
NYIVMLTCAVCLVTYMVMAAIVHKLDQLDASRGHAIPFCGQWGRFKYEILVKTGWGRGSS
STPGEKTETVALQRLGELGPPSPGLNWEQPQAARLSRTGLVEGLRKRLLPAWCASLAHGL
SLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFLGWEPLKVLLEALYFSLVAKR
LHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLAKEEARKVKRLHGMLRSLLVYMLFL
LVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRSEELWPWMAHVLLPYVHGNQSS
PELGPPRLRQVRLQEALYPDPPGPRVHTCSAAGGFSTSDYDVGWGSPHNGSGTWAYSAPD
LLGAWSWGSCAVYDSGGYVQELGLSLEESRDRLRFLQLHNWLDNRSRAVFVELTRYSPAV
GLHAAVTLRLEFPAAGRALAALSIRPFALRRLSAGLSLPLLTSVCLLLFALHFAVAEART
WHREGRWRVLRLGAWARWLLVALTAATALVRLAQLGAADRQWTRFVRGRPRRFTSFDQVA
QLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELLGVTLGLVVLGVAYA
QLAVLLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESWQLSPLLCVGLWALRLWGALRL
GAVILRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLWMGLSKVKEFRHKVRFEGMEPL
PSRSSRGSKVSPDVPPPSAGSDASHPSTSSSQLDGLSVSLGRLGTRCEPEPSRLQAVFEA
LLTQFDLNQATEDVYQLEQQLHSLQGRRSSRAPAGPSRGPSPGLRPALPSRLVRASRGVD
LATGPSRTPLRAKNKVHPSST

>Callithrix jacchus_PKD1(ENSCJAP_27823)
DVSHNLLQALDVGLLANLSALAELDISNNKISTLEEGLFANLFNLSEMSCGSFGGCHWVG
PQVPSIPSASQLVRVSSPGRLCCHRCSKAWGWPLLSIVLWDSGCGEEYVACLPDNSSGTM
EAVAFSPAHEGLLEPEACSAFCFSTGQHLAALSEQGQCLCGAASPNASSACLALCSSPLP
PPAPACGGPTLLQHVFPASSGAALVGPHGPLASGQPAAFHIAAPLPITAAHWDFGDGSPK
VDGAGPVALHRYVLPGHYRVTAVLALGAGSALLETNVQVEAVPATLELVCPSLVQSDESL
QLSVRNRGGSGLEATYSIVALDEEPTRVVHPLCPLDTEIFPGNGHCYRLVVEKAAWLQAQ
EQCRAWAGAALAMVDSPAVQRFLVSQVTRSLDVWIGFSAVQGAGPAPQGEAFSLESCQNW
LPGEPHPATAEHCVRLGPTGWCNTDLCSAPHSYVCELRPGGPVQDAENFLVGAPSGDLQG
PLIPLVQQDDLSAPRQPVEVMVFPVLSLSQEAFLTTAEFGTQELLQPAQLRLQVYRPLST
AGTPENGSEPESGFRDNRTQPAPECMPGGCWCPGANVCLPLDASCHSQACANSCMSGPGL
PKAPYMLWREFLFSVPAGPPAQYSVTLHGQDVLMLPGDLVSLQHDAGPGAFLHCPLASSS
PGLQAPYLSANASAWLPRLPAQLEGARACPACALRLLVATEQFTVLLGLRPNPGLQLPGR
YEVQAEVDNGVSRHSLSCSFNVVSPVAGLRVIAPAPHDGRLYVPTNGSALVLQLDSGANA
TATARWAGGNVSARFEATCPALVATLVPSCPWETNDTLFSVIALPWLSEGEHVLEVVAEN
SASRANLSLQVMAEEPICGLRAMPSPEARVLQGVLVRYSPVVDAGSDVVFRWTINDKQSL
TFQNIVFNVIYQSSAVFKLSLTASNHVSNVTVNYNVTVERMNRMQGLQVSTVPAVLSPDA
SLLLTAGVLVDSAVEVAFLWTFGDGEQALGHFQPPYDESFPVPDPSVAQVLVEHNVTHTY
TAPGEYILTVLASNAFENLTKQVPVSVRSVLPSVAVGMSDSVLVAGRPVTFYPHPLPAPG
GVLYIWDFGDGSPVLMQSQPATNHTYTSRGTYRVRLEVNNTVSSAVAQADLRVFEELRGL
SVDMSLAVEQGAPVVVRAAVETGDNVTWTFDMGDGTVLSGPEATVEHVYLQAQNCTVTVG
AASPAGRLAQSLHVLVFVLEVLRIEPATCIPTQPDARLKAYVTGDPAHYLFDWTFGDGSS
NRTVQGCPEVTHNFTQSGTFPLALVLSSRVNKAHYFTSICVEPEVGNVTLRPEKQFLQLG
VAARLVACVWPPFPYHYAWDFGTEEATSARAAGPRVTFTYRDPGSYLVTVTVSNNVSAAN
DSALVEVQEPVVVTDIEVNGSLVLELQQPYLFSAVGRGRPASYLWDLGDGGQLEGPEVTH
TYNSTGDFTVRVAGWNEVSRSEAWLNVTVKRRVRGLVINASRTVVPLNGSVSFSTLLEAG
SDVRYSWVLCDRCTPIPGGPTMSYTFRSVGTFNVIVTAENEVGSAQDSIFIYVLQLIEGL
QVVGGGGYFPTNHTVQLQAVVRDGTNISYSWAAQREGGPALAGSGRAFSLTTLEASTYHV
QLRATNMLGSAWADCTVVFVEPVGWLMVAASPNPAAINMSVTLSAELAGGSSVLYTWSLE
EGLSWETPEPFTTHSFPMPGLHLVTVTAGNPLGSANATMEVAVQVPVSGLSIRASEPSGS
FVAAGSSVPFWGQLATGTDVSWCWAVPGGGSKYGPHVTMVFPEAGAFSLRLNASNAISWV
STTHNLTVEEPVVGLVLWASSKVVAPGQLVHFQILLAAGSAVTFRLQVGGAGPEVLSGPR
FSRSFPHVGDHVVSVQGENHVSWAQAQVRIVVLEAVSGLQVPNCCEQGIATGTERNFTAR
VQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIQVRAFNALGSENRTLVL
EVQDTIQYVALRSSPCFTNRSAQFEATTSPSPRRVAYHWDFGDGAPGWDTDEPRAEHTYL
RPGDYRVQVNASNLVSFFMAQATVTVQVLACREPEVDVALPLQVLMRRSQRNYLEAHVDL
RDCVTYQTEYRWEVYRTASCQRPGRIARMALPGVDVSRPQLVLPRLALPVGHYCFVFVVS
FGDTPLARSIQANVTVAPERLVPIVEGGSYRVWSDTQDLVLDGSESYDPNLEDGDQTPLS
FHWACVASTQREAGGCALNFGPRGSSMVTIPRERLTAGVEYTFSLTVWKAGRKEEATNQT
VLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGRCLNCSSGSKQGRWAARTFSNKTL
VLDETTTSTGSAGMQLVLRRGVLRDGEGYTFTLTVLGHSGEEEGCASIRLSPNRPPLGGS
CRLFPLGAVHALTTKVYFECSGWQDAEDSSAPLVYALLLRRCRQGHCEEFCVYKGSLSSY
GAVLPPGFRPHFEVGLAVVVQDQLGAAVVALNRSLAIVLPEPNSSAAGLTAWLHGLTASV
LPGLLRQADPQHVIEYSLALVTVLNEAIYEQAPDTAAEPEHERQRRAQIRKNITETLVSL
RVHTVDDIQQIAAALAQCMGPSRELVCRSCLKQTLHKLEAMMRILQAETTAGTVTPTAIG
DSILNITGDLIHLASSDVQGPQPSELGAEPPSRMVASRAYNLTSALMRILMRSRVLNEEP
LTLAGEEIVAQGKRSDPGSLLCYGSAPGPGCHFSIPEAFSGALSNLSDVVQLIFLVDSNP
FPFGYISNYTVSTKVASMAFQTQAGTQIPIERLASERAITVKVPNNSDWAALGHHSPAHS
VVVQPQTSVGAVVTLDSSNPAAGLHLQLNYTLLDGRYLSEEPEPYLAVYLHSEPRPNQHN
CSASRKIRPESLEGTDHRPYTFFIAPGNGDPAGSYYLNLTSHFHWSVLEVSVGLYTSLCQ
YFSEEDMAWRTEGLLPLEETSPQQAVCLTRHLTAFGASLFVPPSRVHFMPPEPTVGVNYI
VLLTCTVCLVTYAVMAAILHKLDQLDASRGRAIPFCGQRGRFKYEILVKTGWGRGSGTTA
HVGIMLYGVDSQSGHRHLDGDRAFHRNSLDIFQIATLHSLGSVWKIRVWHDNKGLSPAWF
LQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDMALWSFRRLLVAELQRG
FFDKHIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVCYGTVGDSAYSTGHVSRLS
PLSVDTVAIGLVSSVVVYPIYLAVLFLFRMSRSKVAVGPSPTPAGQQMLDIDSCLGSSVL
DSSFLTFSGLHAEQAFAGQMKSDLFLDDSKSLVCWPSSEGTLSWPGRFSDPSIVGSNRQL
ARGRAGHGLGPEEDSLSLASPYSPAKS

>Mus musculus_PKD1(ENSMUSP_49296)
MPLGAPALLALALGLGLWLGALAGDPGRGCGPCPLPCFCGPAPDAACRVNCSGRWLQTLG
PSLRIPADATALDLSHNLLQTLDIGLLVNLSALVELDLSNNRISTLEEGVFANLFNLSEI
NLSGNPFECNCGLAWLPRWAKEHQVHVVQSEATTCRGPIPLAGQPLLSIPLLDNACGEEY
VACLPDNSSGAVAAVPFYFAHEGPLETEACSAFCFSAGEGLAALSEQNQCLCGAGQASNS
SAACSSWCSSISLSLNSACGGPTLLQHTFPASPGATLVGPHGPLASGQPADFHITSSLPI
SSTRWNFGDGSPEVDMASPAATHFYVLPGSYHMTVVLALGAGSALLETEVQVEATPTVLE
LVCPSFVHSNESLELGIRHRGGSALEVTYSILALDKEPAQVVHPLCPLDTEIFPGNGHCY
RLVAEKAPWLQAQEQCRTWAGAALAMVDSPAIQHFLVSKVTRSLDVWIGFSSVEGTEGLD
PRGEAFSLESCQNWLPGEPHPATAEHCVRLGPAGQCNTDLCSAPHSYVCELRPGGPVWDT
ENFVMGMSGGGLSGPLHPLAQQETVQGPLRPVEVMVFPGLSPSREAFLTAAEFSTQKLEE
PAQMRLQVYRPSGGAAAVPEGSSEPDNRTEPAPKCVPEELWCPGANVCIPFDASCNSHVC
INGSVSRLGLSRASYTLWKEFFFSVPAGPPTQYLVTLHSQDVPMLPGDLIGLQHDAGPGT
LLQCPLASSCPGQALYLSTNASDWMTNLPVHLEEAWAGPVCSLQLLLVTERLTPLLGLGP
NPGLQHPGHYEVRATVGNSVSRQNLSCSFSVVSPIAGLRVIHPIPLDGHIYVPTNGSVLV
LQVDSGANATATAQWFGGNISAPFEDACPPEVDFLKQDCTEEANGTLFSVLMLPRLKEGD
HTVEIVAQNGASQANLSLRVTAEEPICGLRAVPSPEARVLQGILVRYSPMVEAGSDVAFR
WTIDDKQSLTFHNTVFNVIYQSAAIFKLSLTASNHVSNITVNYNVTVERMNKMHGLWVSA
VPTVLPPNATLALTGGVLVDSAVEVAFLWNFGDGEQVLRQFKPPYDESFQVPDPTVAQVL
VEHNTTHIYTTPGEYNLTVLVSNTYENLTQQVTVSVRTVLPNVAIGMSSNVLVAGQPITF
SPYPLPSTDGVLYTWDFGDGSPVLIQSQPVLNHTYSMTGAYRITLEVNNTVSSVTAHADI
RVFQELHGLTVYLSPSVEQGAPMVVSASVESGDNITWTFDMGDGTVFTGPEATVQHVYLR
AQNFTVTVEAANPAGHLSQSLHVQVFVLEVLHIEPSTCIPTQPSAQLMAHVTGDPVHYLF
DWTFGDGSSNVTVHGHPSVTHNFTRSGIFPLALVLSSHVNKAHYFTSICVEPEIRNITLQ
PERQFVKLGDEARLVAYSWPPFPYRYTWDFGTEDTTHTQTGGSEVKFIYREPGSYLVIVT
VSNNISSTNDSAFVEVQEPVLVTGIRINGSHVLELQQPYLLSAMGSGSPATYLWELGDGS
QSEGPEVTHIYSSTGDFTVRVSGWNEVSRSEAQLNITVKQRVRGLTINASRTVVPLNGSV
SFSTLLEVGSDVHYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSAQDSIFI
YVLQFIEGLQVAGGDNGCCFPTNYTLQLQAAVRDGTNISYSWTAQQEGSLITLFGSGKCF
SLTSLKASTYYVHLRATNMLGSAAANRTIDFVEPVESLILSASPNPAAVNMSLTLCAELA
GGSGVVYTWYLEEGLSWKTSMPSTTHTFAAPGLHLVRVTAENQLGSVNATVEVAIQVPVG
GLSIRTSEPDSIFVAAGSTLPFWGQLAEGTNVTWCWTLPGGSKDSQYIAVRFSTAGSFSL
QLNASNAVSWVSAMYNLTVEEPIVNLMLWASSKVVAPGQPVHFEILLAAGSALTFRLQVG
GSVPEVLPSPHFSHSFFRVGDHLVNVQAENHVSHAQAQVRILVLEAVVGLQVPNCCEPGM
ATGTEKNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIHVRAFN
ELGGVNLTLMVEVQDIIQYVTLQSGRCFTNRSARFEAATSPSPRRVTYHWDFGDGTPVQK
TEEFWADHYYLRPGDYHVEVNATNLVSFFVAQATVTVQVLACREPEVEVALPLQVLMRRS
QRNYLEAHVDLRNCVSYQTEYRWEIYRTASCQRPGRMAQMVLPGVDVSRPQLVVPRLALP
VGHYCFVFVVSFGDTPLARSIQANVTVAAERLVPIIEGGSYRVWSDTQDLVLDGSKSYDP
NLEDGDQTPLNFHWACVASTQSETGGCVLNFGPRGSSVVTIPLERLEAGVEYTFNLIVWK
AGRKEEATNQTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGHCHNCSRGYKQGC
WAARTFSNKTLVLNETTTSTGSTGMNLVVRPGALRDGEGYIFTLTVLGHSGEEEGCASIR
LSPNRPPLGGSCRLFPLDSVRGLTTKVHFECTGWRDAEDGGAPLVYALLLKRCRQSYCEN
FCIYKGSLSTYGAVLPPGFQPLFVVSLAVVVQDQLGAAVVALNRSLTIVLPEPSGNPADL
VPWLHSLTASVLPGLLKQADPQHVIEYSLALITVLNEYEQAPDVSEPNVEQQLRAQMRKN
ITETLISLRVNTVDDIQQITAALAQCMVSSRELMCRSCLKKMLQKLEGMMRILQAETTEG
TLTPTTIADSILNITGDLIHLASLDMQGPQPLELGVEPPSLMVASKAYNLSSALMRILMR
SRVLNEEPLTLAGEEIVALGKRSDPLSLLCYGKALGPSCHFSIPEAFSGALSNLSDVVQL
IFLVDSNPFPFGYISNYTVSTKVASMAFQTQTGTQIPIEQLAAERAITVKVPNNSDQAAQ
SSHNPVGSTIVQPQTSVSAVVTADNSNPQAGLHLRITYTVLNERYLSAEPEPYLAVYLHS
VSQPNEYNCSASRRISLEVLEGADHRLYTFFIAPGTGTLDRSYYLNLTSHFHWSALEVSV
GLYTSLCQYFSEEMMMWRTEGIVPLEETSPSQAVCLTRHLTAFGASLFVPPSHVQFIFPE
PSASINYIVLLTCVICLVTYVVMAMILRKLDQLDVSRVRVIPFCGKGGRFKYEILVKTGW
SRGSGTTAHVGIMLYGEDNRSGHRHLDGDRAFHRNSLDIFQIATPHSLGSVWKIRVWHDN
KGLSPAWFLQHIIVRDLQSARSTFFLVNDWLSVETEANGGLVEKEVLAANEAALWQFQRL
LVAELQRGFFDKHIWLSIWDRPPRSRFTRVQRVTCCVLLLCLFLAANAVWYGVVRDTTYS
MGPVSSLISPGVDTVAIGLVSSVVVYPVYLAVLFLFRMSRSKVSGDQNPTPTGQQALDVD
SYLDPSVLDSSLLTLSGLTEAFAGQVKNDLFLEDAKSLVCWPSSEGTLSWPDLLSDPSVV
SSTLQRLTQGRPGCMLGSEEDGASLVSPSLPAKYLSASDEDLIHQVLADGANNLVPTQDT
LLETDLLTSLSSVPGEKTETLILQTVGEERPASMGLSWEQSPVTRLSRTGLVEGFQKRLL
PAWCAPLAHGLSLLLVAVAVAVSGWIGASFPPSVSVMWLLSSSSSFLASFLGWEPLKVLL
EALYFSLVAKRLHPDEDDTLVESPAVTPVSERVPRVRPPHGFALFLAKEEARKVKRLHDM
LKRLLVYMLFLLVTLLANYGDASCHGHAYRLQSAIKQELDSQAFLAITRSDEFWPWMSHV
FLPYVHGNQSSPELGPPRLRQVRLQEAFCPDPSSSEHMCSAAGSLSTSDYGIGWQSVVQN
GSETWAYSAPDLLGAWYWGYCAVYDSGGYIQELGLSLEESRARLGFLQLHNWLDSRSRAV
FVELTRYSPAVGLHAAVTLRLEFPVAGHALAAFSVRPFALRRLSTGLSLPLLTSVCLLLF
ALYFSMAEVQTWRKDGCACTARPDTWARCLLVILTAATGLVRLAQLGIADRQWTHFVQDH
PRHFTSFDQVAQLGSVARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELMGAT
LGLVLLGVAYAQMAILLISSGADTLYNMARAFLVLCPGARVPTLCPSESWYLSPLLCVGL
WALRVWGALRLGAILLRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLWMGFSKVKEFR
HKVRFEGMDPLPSRSSRGSKSSPVVLPPSSGSEASHPSTSSSQPDGPSASLSRSTLKLEP
EPSRLHAVFESLLVQFDRLNQATEDVYQLEQQLQSLQGHGHNGPPSSPSPGCFPGSQPAL
PSRLSRASQGLDQTVGPNRVSLWPNNKVHPSST

>Rattus norvegicus_PKD1(ENSRNOP_15092)
MPPGAPARLALALGLGLWLGALAGDPGRGCGPCPLPCFCSPAPDAACRVNCSGRWLQTLG
PSLRIPADATALDLSHNLLQTLDIRLLVNLSGLVELDLSNNRISTLEEGVFANLFNLSEI
NLSGNPFECNCGLAWLPRWAKEQQVHVVQSEATTCRGPVPLAGRPLLSTPLLDNACGEEY
VACLPDNSSGAVAAVPFFFAHQGPLETAACSAFCFSAGEGLAALSEQNQCLCGAGQPSNT
SAACSSWCSSILLSFNSACGGPTLLQHTFPASPGAALVGPHGPLASGQPADFHINSPLPI
SSTCWNFGDGSPEVDMAGPAATHSYVLPGGYHVTVVLTLGAGSALLETEVQVEVAPTVLE
LVCPSFVHSDESLDLGIRHRGGSALEVTYSILALDKEPAQVVHPLCPSDTEIFPGNGHCY
RLVAEKAPWLQAQEQCRTWAGAALAMVDSPAIQHFLVSKVTRSLDVWIGFSSVEGKEGLD
PQGEAFSLESCQNWLPGEPHPATEEHCVRLGPAGQCNTDLCSAPHSYVCELRPGGPVGDA
DNFLLGVSGGGRSGPLQPLAQQGTLQGPLQPVEVMVFPGLSPSQEAFLTAAEFETQELED
PVQLRLQVYRHSREAVAPEGSSELDNSTEPAPKCVPEELWCPGANVCVPFDALCNSHVCI
NGSASRLGLPRASYTLWKEFFFSVPAGPPTQYLVTLHGQDVPMLPGDLVALQHDAGPGTF
LHCPLASSCPGQALYLSTNASDWMTNLPVHLEEAWAGPVCSLQLLLVTEQLTPLLGLGSN
PGLQHPGHYEVRATVGNSISRQNLSCSFSVVSPVAGLRVIHPIPLDGHIYVPTNGSILVL
QVDSGANATATAHWFGGNVSAPFEDACPPEVDFLKQDCTEEANGTLFSVLVLPRLKEGDH
TVEIVAQNGASQANLSLRVTAEEPICGLRAVPSPEARVLQGILVRYSPMVEAGSDVAFRW
TIDDKQSLTFHNTVFNVIYQTAAVFKLSLTASNHVSNITVNYNVTVERMNKMHGLWVSAV
PAVLPPNATLALTGGVLVDSAVEVAFLWNFGDGEQVLRQFKPPYDESFQVPDPTVAQVLV
EHNTTHIYNTPGEYNLTVTVSNTYENLTQQVPVSVRTVLPNVTIGMSSNVLLAGQPITFF
PYPLPSADGVLYTWDFGDGSPVLIQSQPVLNHTYSMTGTYRISLEVNNTVSSVAAHVDIC
VFQELHGLTVYLNQSVEQGAPMVVNASVESGDNITWTFDMGDGTVFTGPEATVEHVYLRA
QNFTVTVGATSPAGHLSQSLHVQVFVLEVLRIEPSTCIPTQPSAQIMAHVTGDPAHYLFD
WTFGDGSSNVTVHGHPSVTHNFTRSGIFPLALVLSSHVNKAHYFTSICVEPEICNVTLQP
ERQVVKLGDEAWLVAYPWPPFPYRYTWDFGTEDSIHTQTGGSEVTFIYREPGSYLVIVTV
SNNISSTNDSAFVDVQEPVSVTGIRINGSHVLELQQPYLFSAMGNGSPAAYLWELGDGSQ
HEGPEVTHIYSSTGDFTVRVSGWNEVSRSEAQLNITVKQRVRGLTINASRTVVPLNGSVS
FSTLLEVGSDVHYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSAQDSIFIY
VLQLIEGLQVVGGDGGCCFPTNYTLQLQAAVRDGTNISYSWTAQQDGGPTLISSGKSFSL
TALKASTYYVHLRATNMLGSASANRTIDFVEPVESLILSASPNPAAVNTSLTLGAELAGG
SGVVYTWYLEEGLSRETSMPSTTHTFAAPGLHLVRVTAENQLGSVNATIEVAVQAPVGGL
SIRTSEPDSIFVAAGSTVPFWGQLAEGTNVTWCWTLPGGSKYSQYIDVRFPAAGHFSLWL
NASNAVSWVSAVYNLTVEEPIMNLVLWASSKVVAPGQPVHFQILLAAGSAVTFRLQVGGS
IPEVLPSLHFSHSFFRVGDHMVSVQAENHVSRAQAQVRILVLEAIVGLQVPNCCEPGMAT
GTEKNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGILEIHVRAFNEL
GGVNLTLVVEVQDIIQYVTLQSGRCFTNRSARFEAATSPSPRRVTYHWDFGDGTPVQETE
ESWTDHYYLHPGDYRVEVNATNLVSFFVAQATVTVQVLACREPEVEVALPLQVLMRRSQR
NYLEAHVDLRNCVSYQTEYRWEVYRTTSCQRPGRMTQMVLPGVDVSRPQLVVPRLALPVG
HYCFVFVVSFGDTPLARSIQANVTVAAERLVPIIEGGSYRVWSDTQDLVLDGSKSYDPNL
EDGDQTPLNFHWACVASTQSETGGCVLNFGPRGSSVVTIPLERLEAGVEYTFNLIVWKAG
RKEEATNQTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGHCHNCSSGSKQGRWA
ARTFSNKTLMLNENTTSTGSTGMHLVVRPGALHDGEGYIFTLTVLGHSGEEEGCASIRLL
PNRPPLGGSCRLFPLESVRGLTTKVHFECTGWRDAEDGGAPLVYALRLKRCHQNYCEDFC
IYKGSLSTYGAVLPPGFQPLFVVSLTVVVEDQLGASVVALNRSLTIVLPEPSGNPADLIP
WLHSLTASVLPGLLRQADPQHVIEYSLALITVLNEYEQAPDMVSEPNLEQQLRAQMRKNI
TETLISLRVNTVDDIQQITAALAQCMVSSRELMCRSCLKKMLQKLEGMMRILQAETTEGT
LTPTTIADSILNITGDLIHLASLDMQGPQPLELGAEPPSLMVASKAYNLSSALMCILMRS
RVLNEEPLTLAGEEIVALGKRADPLSLLCYGKAWGPSCHFSIPEAFSGALSDLSDVVQLI
LLVDSNPFPFGYISNYTVSTKVASMAFQTQTGTQIPIEQLAAERAITVKVPNNSDQAAQS
SHSPVGSTIVQPRASVSAVVTADNSNPQAGLHLRITYTVLNARYLSEEREPYLAVYLHSV
SQPNEYNCSASRRISLEVLEGADHRPYTFFIAPGTGTLGRSYYLNLTSHFHWSALEVSVG
LYTSLCQYFSEEAMMWRTEGIVPLEETSPSQAVCLTRHLTAFGASLFVPPSHVQFIFPEP
SVSINYIVLLTCVICLVTYVIMAMILRKLDQLDVSRVRVIPFCGKGGRFKYEILVKTGWS
RGSGTTAHVGIMLYGEDNRSGHRHLDGDRAFHRNSLDIFQIATPQSLGSVWKIRVWHDNK
GLSPAWFLQHIIVRDLQSARSTFFLVNDWLSVETEANGGLVEKEVLAANEAALWQFQRLL
VAELQRGFFDKHIWLSIWDRPPRSRFTRVQRVTCCVLLLCLFLAANAVWYGVVGDTTYSM
GPVSSLMSPSVDTVAIGLVSSVVVYPVYLAVLFLFRMSRSKVSGDQNPTPTGQQALDVDS
YLDPSVLDSSLLTLSGLTEAFSGQVKNDLFLEDAKSLVCWPSSEGTLSWPDLLSDPSVMS
STLQRLAQGRPGCMLGSEEDGASLVSPSLPAKYLSASDEDLIHQVLADGANNPDPTQDAL
IERDLLTSLSSAPGEKTETLILQTMGEKRPPSMGLTWEQSPVTRLSRTGLVEGLRKRLLP
TWCAPLAHGLSLLLVAVAVAVSGWIGASFPPSVSVMWLLSSSSSFLASFLGWEPLKVLLE
ALYFSLVAKRLHPDEDDTLVESPAVTPVSERVPRVRPPHGFALFLAKEEARKVKRLHDML
KSLLVYMLFLLVTLLANYGDASCHGHAYRLQSAIKQELDSQAFLAITRSDEFWPWMSHVL
LPYVHGNQSSPELGPPRLRQVRLQEAFCPDPSSSEHMCSATGSLSTSDYGIGWQSVVQNG
SETWAYSAPDLLGAWYWGYCAVYDSGGYIQELGLSLEESRARLGFLQLHNWLDSRWVLMF
VELTRYSPAVGLHAAVTLRLEFPVAGHALAAFSVRPFALRRLSTGLSLPLLTSVCLLLFA
LYFSVAEVHTWRREGCARTARPEAWARWLLVMLTAATGLVRLAQLGIADRQWTRFVHDHP
HHFTSFDQVAQLGSVARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELMGATL
GLVLLGVAYAQMAILLISSGADTLYSMARAFLVLCPGARVPTLCPSESWYLSPLLCVGLW
ALRVWGALRLGAVLLRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLWMGFSKVKEFRH
KVRFEGMDPLPSRSSRGSKSSPVVPPPSAGSEASHPSTSSSQPDGLSAGLGRSALRLEPE
PSRLHAVFESLLVQFDRLNQATEDVYQLEQQLQSLRGHGHSGPPSSPSPGGFPASQPALP
SRLARASQGPDQTTGPSRVSLWPNNKVHPSST

>Canis familiaris_PKD1(ENSCAFP_28717)
DVSHNLLRALDVGLLANLSALTELDISNNKISTLEEGIFSNLFNLSEINLSGNPLECDCG
LAWLPRWAEEQQVHVVRPEAATCAGPGPLAGQPLLGVPLLDGGCGEEYIACLPDNSSGAV
ALVAFSAAHEGPLTPEACGAFCFAAGNGLGAFSDQGWCLCGAAQPPNTSSACLPFCSGAP
LALAPACGGPTLLQNIFPASPGAALVGPQGPLASGQPAAFHVTASLPVSSTRWDFGDGSP
KVDIAGPATTHRYLLPGLYHVTVVLALGAGSAQVETQVHVEAAPASLELTCLTSVRSDET
LKFGIRNRGGSDLEATYSIVAVGEEPAQAADPAVVHPLCPSDTVIFPGNGHCYRLVAEKA
AWLQAQEQCRAWAGAALAMVDSPAIQHFLVSQVTRSLDVWIGFSAVEGAEAGPVVQGAAF
SLESCQNWLPGEPHPATAERCVRLGPAGQCNTDLCSAPHSYVCELRPGGPVWDAENFLVG
APIGDLQGPLSPLAQQEALSAPQELIEVMVFPSLGLSREAFLTAAEFGTQELRRPTQLRL
QVFRPVGEAGAPGNSREPESGSRESRTESVPECTPEGRWCPRASIHLPPDDPCGPWACAN
GSMSGPGLPGASCVLLREFLFSVPAGPPSQYSVTFRGQDGPLKPGDLIALQHDAGPGALL
CCSPALGAPGAEAPYFSATSPAWLVHLPAQLEAAPAGPACALRLLVATERLTTLLGLRPN
PGLRRPGRYEVRATVGNSVSTHNLSCSFDVLSPVAGLRVAHPIPHDGRLYVPTNSSVLVL
QVDSGTNATATARWPGGNASAPFEATCPATVAALVPSCTLEANDTLFAVLVLPGLSEGEH
AVEIMVENSAGHANLSLRVKAEEPICGLRAAPSPEARVLQGVLVRYSPVVEAGSDVVFRW
TIDDKQSLTFPHVVFNVIYQSAAVFSSRLTASNHVSNVTVNYNVTVERMHKMKGLRVSAV
PPVLPPNTTLELAAHVLVDSAVEVAFLWTFGDGDQVLGQFKPPYNESWVPDPTVAQVLVE
HSVTHVYAVPGEYNLTLLVSNAFENLTQQVPVSVRATLPAVAVAVGSHVLVAGQPVTFSP
HPLPSPGGILYTWDFGDGSPAVTQHQTEVSHTYASRGIYRIHLEVNNTVSSVTAWTSVRV
FEELRGLSVSLSPSVEQGAPVTVSATLESGDNVTWTFDMGDGTVLVGPEAMVEHVYLRAQ
NHTVTVGVSSPAGYLALSLPVHVFVLEVLRIEPAACIPVQPHTWFMAHVTGDPAHYIFDW
TFGDGSSNTTIFGDPTVTHNFTRSGTFPLALVLSSHVNKAHYFTSVCVEPEVGNVTLWPE
RQFVRLGDEAHLVARAWPPFPYRYTWDFGPEDAPRVGGPEATFTYADPGSYLVTVAVSNN
ISAANDSALVEVEEPVELTGIGVNGSGVLELQRPYLFSAVGRGHPATYLWELGDGGRLEG
PSIKHTYNSTGHFTVRVSAWNEVSRGEAWLNITVQRRVQGLSVNASRTVVPLNGSVSFTT
SLEAGSDVRYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSAQDSIFIYVLR
HIEGLQVAGGGGGCCFPTNCTLQLQAVVSDGTNISYSWSAQRDGGPALAGSGKAFSLTVL
EAGTYHVQLRAANMLGTSWANRTVDFVEPVGALAAAASPNPAIVNSSVTLCAELAGGSGV
TYTWSPEGGLSWETPEPSSTHVFPSPGLYLVRVTATNWLGSANVTIEVAVQVPVSGLSIR
AGDIDRGFVAAGSAVPFWGQLDSGTNVSWCWTVPGGSRRGQHVAVVFRDAGAFSVRLNAS
NAVSWVTATRELTVEEPIAGLVVWADSKVVEPGQLVHFQVMLAAGSAVRFHLQVSGAAVE
ALPGPRFSRSFPRVGDYMVSVQAENHVSRAQAQVRILVLEAVGGLQVPHCCELGIPTGTE
RNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIHVRAFNDLGGV
NLTLLMEVQDAIQHVVLRSGRCFTNRTARFEAATSPSPRRVAYRWDFGDGAVVEDTEEPW
AEHSYLRPGDYRIEVNASNLVSFFVAQATVTVHVLACREPEVDVALPPQVLMRRSQRNYL
EAHVNLRDCVTYQTEYRWQVYRAASCQRPGRLAPVALPSVDMSRPQLVVPRLALPVGHYC
FVFMVSFGDTPLARSIQANVTVVPERLVPIVEGGSYRVWSDTQDLVLDGSKSYDPNLEDG
DQTPLSFHWACVASTQSETGGCTLTFGPRGSSVVIVPRERLQAGVEYTFNLTVWKAGRKE
EATNQTVLIRRGRVPIVSLECVSCKAQSVYAVSRKSYVYEGRCDNCSEGSKRGRWAARTF
SNQTLVLDETTTSTGSSGMRLVLRRGVLRDGEGYTFTLTVLGRSGEEEGCASIRLSANRP
PRGGSCRLFPLDAVRALTTKVHFECTGWQDAEDASAPLVYALLLRRCRQGHCEEFCVYRG
SLSAYGAVLPPGFAPHFQVGLAVVVQDQLGAAVVALNRSLAITLPQPPGDPQGGPTDLTS
WLHGLTESMLPRLLRQADPQHVIEYSLALITVLNEASAGSEQVLAVVAEEDARRQLQAQI
RKNVTETLVSLRVNTVDDIQQIAAALAQCTVSSRELVCHSCLKKTLHKLEAMMRILQAET
AAGTGTPTGIADSILNITGDLIHLASVDMQGLQPSELGTEPPSLMVASRAYHLSSALMCI
LMRSRVLNEEPLTLAGEEIVAQGKRSDPLSLLCQGNASVPSCHFSIPTAFSGALSNLSDV
VQLMFLVDSNPFPFGYISNYTVSTKVASMAFQTQAGTQIPIGQLASERAIIVKVPNSSDQ
AAPGHRAPAGSAVIQPQASISVAVTPENSNPAAGLHLQLTYTLLNERYLPEEPEPYLAVY
FDSVPGPNEHNCSASRRISLEELAGGDHRPYTFFIAPGTRDSGGTYYLNLTSHFHWSALE
VSVGLYTSLCQYFSEKEMMWKTEGLVPLEETSPSQAVCLTRHLTAFGASLFVPPSHVHFI
FPEPASGVNYIVLLTCIVCLVTYTVMAVILRKLDQLDVSRVRIIPFCGKGGLFKYEILVK
TGWGRGSGTTAHVGIMLYGAEGRSGHRHLDGDRAFRRNSLDVFQIATPHSLGSVRKIRVW
HDNKGLSPAWFLQHIIVRDLQNARSTFFLVNDWLSVETEANGGLVEKEVLAASEAALRRS
RRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRVQRATCCILLVCLFLGANAVWYGVVGDT
ASSAGPVSTLIPLSVDTIAVGLVSSVVVYPVYLVILFLFRMSRSKVAGAPSPTPAGQQVL
DVDSYLDSSVLDSSFLTFPGLRTEAFAGQMKSDLFLDDSKSLVCWPSSEGTLNWPDLLSD
PSIMGSTLQRLARGRTGHTLGPEDDGLSLLSPSSPAKYFSASDEDLIQQILAEGASSLAP
TQDTQVETDLLTSLSSAPGETTETLTLQRLGERGPPCSSGVTWEQPTSARLSGTGLADGL
QKRLLPAWCASLAHGLSLLLAAVAVGVSGWVGSSFPPGVSVMWLLSSSSSFLASFLGWEP
LKVLLEALYFSLVAKRLHPDEDDTLVESPAVTPVSERVPRVRPPHGFALFLAKEEARKVK
RLHGMLRSLLVYMLFLLVTLLANHGDASCHNHAYRLQSAIKQELGSQAFLAITRSDEFWP
WMSHVLLPYIHGNQSGPELGPPRLRQVRLQEALCPDPPGAAVHACSAGQDAFSTGDYSIG
WGSAAQNCSETWAYSAPDLLGIWSWGYCAVYDSGGYVQELGLSLEESRAQLGFLQLHNWI
DNRSRAVFVELTRYSPAVGLHAAVTLRLEFPAAGHAVTAVSVRPFPLQRLSTGLSLPLLT
SVSLLLFALYFSVAEVRTWRREGCRRAAQPGAWARWLLVALTAAAALVRLAQLGVADRQW
ARFLRRRPRRFTSFEQVAQLSAAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRAL
PELVGAALGLVALAVAYAHLAVLLVSSCVDSFRSAARALLVLCPGSGGPALCPAESWRLS
PLLCTGLWALRLWGALRLGAVLLRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLWMGF
SKVKEFRHKVRFEGMEPLPSRSSRGSKSSPDAPPPSGGSDTSRPSTSSSQLDTLSGGLGR
LGPRGEPEPSRLQAVFEALLTQFDRLNQATEDVYQLEQRLQSLRGRRSTVPPASPPHSPC
SALQPALPSRLARASRGMGLASGPSRASLRAKNKVHPSST

>Felis catus_PKD1(ENSFCAP_2042)
DVSHNLLRALDAGLLANLSALTELDISNNKISTLEEGLFANLFNLSEINLSGNPLECDCG
LAWLPRWVEEQQVRVVRPEAATCAGPGPLAGRPLLGVPLSDSGCGEEYIACLPDNSSGAV
VPVAXAGWGLGALSDQGWCLCGAAQPPNASSACLPLCSSPPLPLAPACGGPTLLENVFPA
SPGAALVGPPGPLASGQPAAFHVTASLPVSSTHWDFGDGSPKVDVAGPATTHRYSLPGHY
QVTAVLALGAGSAQLGAKVQVEAAPAALELECPVSVLSDETLKLGVRNRGGSGLEATYSI
VSLGEEPGRVVHPLCPSDTVIFPGNGHCYRLVAEKAAWLQAQEQCQAWAGAALAMVDSPA
VQRFLVSQVTRSLDVWIGFSAVEGAEAGPAVRGEAFSLESCQNWLPGEPHPATAERCVRL
GPAGQCNTDLCSVPHSYVCELRPGGPVWDAENFLVGAPPGDLQGPLSPLAQQEALSAPQE
PVEVMVFPSLGLSREAFLIAAEFGTQELHRPAQLRLQVFRPEGGAGAPGHGGEPESASLE
SQARPVPACTPEGRWCPQTGIPLSPDTLCRPRACANTSTSGPGPPGTSCVLWKEFLFSVP
AGPPTHYSVPFQGQDGPLLPGDLVTLQHDAGPGALLHCSPALGPPGPEAPYLSAVASAWL
AHLPAQLEVAPTGPACALRLLAATERLTPLLGLRPNPGLRRPGHYEVRATVGNSVSMHNL
SCDFDVLSPVAGLRVAHPTPHDGRLYVPTNGSVLVLRVDSGTNATATAHWPGGNVSAPFE
AAXVVENSAGQANLSLQVKAEEPICGLRATPSPEARVLQGVLVRYSPMVEAGSDVVFRWT
IDDKQSLTFHNVVFNVIYQSAAVFKLSLTASNHVSNVTVNYNVTVERMNRMRGLWVSAVP
PVLPPNATLALAAHVLVDSAVEVAFLWTFGDGDQVIGQFKPPYSESFRVPDPAVAQVLVE
HNVTHAYAIPGEYNLTLLVSNAFENLTRQVSVSVRATLPAVAVAVGSRVLVAGQSVTFAP
RPLPSPGGILYTWDFGDGSPAVTQHRPEVNHTYSSGGEYRVRLEVNNTVSSVTACVGIRV
FEELRGLSVSLSPSVEQGAPVTVSATLESGDNVTWTFDMGDGTVLTGPEATVEHVYLRAR
NCTVTVGASSPAGRLALSLPLQVFVLEVLRIEPAACIPVQPLARLTAHVTGDPTHYIFDW
TFGDGSSNTTVSGDPTVTHNFTRSGTFPLTLVLSSHVNKAHYFTSVCVEPELGNVTLWPE
RQFVRLGDEARWVARAWPPFLYRYTWDFGTEDPARVGGPEATFAYPASGSYLVTVAVSNN
ISAANDSALVEVQEPVELTGVRVNGSRVLELQQPYLFSAVGRGCPATYLWELGDGGLLEG
SAVTHAYNSTGHFTIRVTGWNEVSRGEARLNVTVRERARGLSVNASRTVVPLNGSVSFTT
SLEAGSDVRYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGAAQDSIFVYVLQ
HIEGLQVVGGGGGCCFPTNRTLQLQAVVRDGTNISYSWTAQRDGGPALAGSGRAFSLTVL
EAGTYHIQLRAANMLGSALANRTVDFVEPVGWLAAAASPNPAAVDASVTLCAKLAGGSGV
IYSWSLEGGLSWETPEPSTTHTFPTPGLYLVTVTARNQLGSANATTEVAVQVPVSGLSIR
AGELGGSFVAAGSAVPFWGQLDSGTDVSWCWEVPGGSRHGQHVSVVFRDAGAFSVRLNAS
NAVSWGLATRELTVEEPVAGLVLWASSKVVAPGQPVHLQVLLAAGSAVSFYLQVGGAAPE
ALPGPRFSRSFPRAGDYTLSVQAENHVSRAQAQVRILVLEAVGGLQVPAGLLEIHVRAFN
ELGGVNRTLVVEVQDTIQHVVLRSGRCFTNRSARFEAATSPSPRRVAYRWDFGDGAPAED
TEEPWAEHSYLRPGDYRVEVNASNLVSFFVAQATVTVHVLACREPEVDVALPPQVLMRRS
QRNYLEAHVNLRDCVTYQTEYRWEVYRAAGCHRPVRMAPVALPSVDMSRPQLVVPRLALP
VGHYCFVFLVSFGDTPLARSIQANVTVVPERLVPIIEGGSYRVWSDTQDLVLDGSKSYDP
NLEDGDQTPLSFHWACVASTQSETGGCTLAFGPRGSSVVTVPRERLQAGVEYTFNLTVWK
AGRKEEATNQTVLIRRGRVPLVSLECVSCKAQAVYAVSRSSYVYLEGRCDNCSGGSQRGR
WAARTFSNETLVLDETTTSTGSSGMRLVVRRGVLRDGEGYTFTLTVLGRSGEEEGCASIR
LSANRPPRGGSCRLFPLDAVRALTTKVHFECTGWQDAEDAGAPLVYALLLRRCRQGHCEE
FCVYRGSLSAYGAVLPPGFAPHFQVDLAVVVQDQLGAAVVALNRSLAITLPELPSDLPGG
PLDLTTWLHSLTESMLPRLLRQADPQHVIEYSLALITVLNEHEQALASSAESDPRRQLQA
QIRKNVTEILVSLRVNTVDDIRQIAAALAQCTVSSRELVCRSCLKKTLHKLEGMMHILQA
ETAEGTGTPTAIADSILNITGDLIHLASADVQGPQPSELGAEPPSLMVASRAYHLSSALM
CILMRSRVLNEEPLTLAGEEIVAQGKRSDPLSLLCQGDASVPGCHFSIPEAFSGALSNLS
DVVQLIILVDSNPFPFGYISNYTVSTKVASMAFQTQAGAQIPIGRLASERAITVKVPNNS
DQAARGCRTPAGSAVVQPQASVGVVVVPEDNNPDAGLHLQLTYSVLSEHYLSREPEPYLA
VYLHSVPQPNEHNCSASRRIGPEALAGRDHRPYTFFIAPGSRDPGGTYYLNLTSHFRWSA
LEVTVGLYTSLCQYFSEKDMMWRTEGLVPLEETSPSQAVCLTRHLTAFGASLFVPPSHVR
FIFPEPASGVNYVVLLTCSVCLVTYVVMAVILRKLDQLDVSRVRVIPFCGKGGRFKYEIL
VKTGWGRGSGTTAHVGIMLYGAEGRSGHRHLDGDRAFRRNSLDVFQIATPHSLGSVRKIR
VWHDNKGLSPAWFLQHIIVRDLQTACSTFFLVNDWLSVETEANGGLVEKEVLAASDAAVR
RFRRLLVAELQRGFFDKHLWLSLWDRPPRSRFTRVQRATCCVLLVCLFLGANAVWYGVVG
DAAYSAGPVSGLIPLSADTVAVGLVSSVVVYPVYLVILFLFRMSRSKVAGGPSPTPAGQP
VLDIDSYLDSSVLDSSFLAFPGLRAEAFAGQMKSDLFLDDCKSLVCWPSSEGTLNWPDLL
SDPSIVGSTLQRLARGRLGPEEDGLSLVSPSSPAKSFSASDEDLIRRIVAEGAGSLAPAR
DAQIETDLIAGLSSAPAERTETLMLQRLGDRGLPSPGLTWERPQSAKPARTGLVDGLRRR
LLPAWCAPLAHGLSLLLVAVAVGVSGWVGASFSPGVGVMWLLSSSSSFLASFFGWEPLKV
LLEALYFSLVAKRLHPDEDDTLVESPAVTPVSERVPRVRPPHGFALFLAKEEARKVKKLH
GMLRSFLVYMLFLLVTLLANHGDASCHSHAYRLQSAIKQELGSQAFLAITRSEEFWPWMS
HVLLPYIHGNQSSPELGPPRLRQVRLQEALCPDPARPGVPVCAAAAGSFSTGDYGIGWGS
AAHNGSEMWAYSAPDLLGVWSWGYCAVYDSGGYVQELGLSLEESRAQLGFLQLHNWIDNR
SRAVFVELTRYSPAVGLHAAVTLRLEFPVAGHAVTAVSVRPFALRRLNRALPELVGAALG
LVVLAVAYAQLAILLVASCVDSFRSALRAVLVPCPGSGGPAPCPAESWRLSPLLCTGLWA
LRLWGALRLGAVLLRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLWMGFSKVKEFRHK
VRFEGMEPLPSRSSRGSKSSPDAPPPSGGSDASRPSTASSQLDTPGGAEPAGPRGEPEPS
RLQAVFEALLTQFDRLNQATEDVYQLEQRLQSLQGRRSTGAHSPSSDLRPALPGRLARAS
RGVGLAPGPCRVSLRAKNKVHPGST

>Bos taurus_PKD1(ENSBTAP_27480)
MPPAAPARLALALGLGLWLGALAGVPGRGCGPCAPPCLCGPAPGAACLVNCSGQGLRTLG
PALRIPADATALDVSHNLLQALDIGLLANLSALMELDISNNKISTLEEGIFANLFNLSEV
NLGGNPLECDCGLAWLPRWVEGQRVRVVRPEAATCAGPGPLAGQPLLGGALLDGACGEEY
VACVPDDSSGAVALVAFLAAPEGPLAPEACSALCFEAGQALAALSEQGRCLCGAARPPNA
SSACLPSCSGPSLPLAPACRGPSLLQHVFPASPGATLLGPQGPLASGQPAVFHVTALLPV
SSTHWDFGDGSPEVDVTGPDATHRYVLPGRYPVTAVLALGVGSARLGVEVRVEAAPAALE
LVCVASVHSEETLQLSVRNRGGSGLEAAYSIVALGEEPAQVVHPLCPSDTEIFPGNGHCY
SLRAEKASWAQAQEQCRAWAGAALAMVDSPAVQHFLVSRVTRSLDVWIGFSAVEGAAAGP
APQGGAFSLESCQNWLPGEPHPATAERCVRLGPAGQCNTDLCSAPHSYVCELRPGGPVWD
AENFLVGAPNGDLQGPLSPLEQQEALLAPQEPVEVMAFPGLSPSREAFLTAAEFGTQELG
RPAQLRLQVYRAGRGAGAPGNSSEPQGRSLENRTELAPVCAPEGPLCPQANVCLPLDTPC
HPGACANGSMPGPGLPGVSYVLQKEFLFSVPAGPPAQYSVPFHGQDIALLPGDLVILQHD
AGPGTLLRCPPALSFPGSEAPYFSANASAWLAHLPAQLEAAPAGPACALRLLAATERLTP
LLGLGPNPGLRRPGRYEVRATVGNSVSRHNLTCIFDVLSPVAGLRAIYPAPQDGRLYVPT
SGSPLVLQVDSGANATAEARWPGGNASAPFEAACPAAVAALAPGCAQEANGSLFSMLTLP
GLREGEHEVEVVVENGAGRANLSLLVTAEEPIRGLRATPSPEARVLQGVLVRYSPAVEAG
SDVVFRWTIDDKQSLTFHNVVFNVIYQSAAVFKLSLTASNHVSSVSAHFNVTVEPMQRMR
GLCVSAVPPVLAPNATLALAAHVLVDSAVEVAFLWTFGDGQQAVGQFKPPYDSFEVPDPT
VAQVLVEHNTSHTYTFPGEYSLSLLVSTAFENLTQQVPVSVRAALPAVAVAVGSQVLVAG
RPVAFFPRPLPSPGGVLYTWDFGDGSPAVTQPQPEVNHTFALRGTYRVRLEVNNTVSHTV
ADVSVRVFEELCGLTVSLSPAVEQGVPTVVSAALDSGDNVTWTFDMGDGTVLTGPEATVE
HVYRRAQNCTVTVSASSPAGHLARSLPVHVFVLEVLWIEPVACIASQPHARLTAHVTGDP
AHYVFDWTFGDGSPNVSIQGDPTVTHSFTHSGTFPLALVLSSRVNRAHYFSSVCVEPELG
NVTLQPERQFVRLGDEARLVAHAWPPFPYRYTWDFGAEDGATHVGGPEATFTYQLAGSYL
VTVTAANNISATNDSALVEVQEPMEVTGIRVNSSHALELQQPYLFSAVGRGHPASYLWEL
GDGRQLQGPTVTHAYSSTGCFQVRVAGWNEVSRGEARLNVTVQRRVRGLSLNASRTVVPL
NGSVSFSTVLEAGSDVHYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGAAQD
SIFVYVLQHIEGLQVVGGGCCFPTNRTLQLQAVVRDGTNISYSWAAQRDGGPTLAGSGKA
FSLTVLEAGTYHVQLRATNMLGSASANCTVDFVEPVGWLAVTASPNPAAVNTSVTLWAEL
AGGSSVIYSWSLEEGLCWETREPSTTLIFPSPGLCLVTVVAKNQLGSANASVEVVVQVPV
GGLSIQARELDGGFVVAGSTVPFWGQLAVGTDVSWRWAVPGGSRQGQHITVVLPDAGPVS
IQLNASNAVSWVTATHNLTVQEPIVGLVLWASRKVVEPGQPVHFQILLAAGSAVRFLLQV
GGGGLEVLPTPHFSRSFPRVGDYTVSVHAENRVSRAQAQVRISVLEAVGGLQVPDCCGPA
IATGAERNFSARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIHVRAF
NELGGVNCTLLVEVQDAIQHVVLRGPRCFANRSAHFEAATSPSPRRVSYHWDFGDGAPVE
DTEGPWAVHSYLQPGDYPVQVNASNLVSFFVAQATVTVHVLACREPAVDVALPPQVLMRR
SQRNYLEAHVDLRDCVTYQTEYRWEVYRATSCQRPGRAARVALPGVDVSRPQLVVPRLAL
PVGHYCFVFVVSFGDTPLARSIQANVTVAPERLVPIVEGGSSRVWSDSQDLVLDGSKSYD
PNLEDGDQTPLSFHWACVAATQSETGGCALNFGPRGSSVVTIPRERLRAGVEYTFNLTVW
KAGRKEEVTSQTVLVRSGRVPIVSLECVSCKAQAVYAVSRSSYVYLEGRCDNCDGGLEHG
LWAARSFSNETLVLDATTTSTGSTGMRLVVRRGVLRDGEGYTFTLTVLGRSGQEQGCASI
RLAPNRPPRGGSCRLFPVEDVRALTTKLHFECTGWQDAEDAGAPLVYALQLRRCRQGHCE
EFCVYKGSLASYGAVLPPGFAPHFVVGLAVLVQDQLGAAVVALNRSLTITLPDPPGDPAD
GPLDLMGWLHSLAGSTLPGLLRQADPQHVMEYSLALIAVLNEYEQTLPVLAEPDPRQELR
AQIRKNITETLVSLRVNTVDDIQQVAAALAQCTVSSRELVCRSCLKKTLHRLEDMMRILQ
AETATGAGTPTTIADSILNITGDLIHVASSDVQGPQPSELGAEPPSLLVASRAYQLSSAL
VGILTRSRVLNEEPLTLAGEEILAQGKRSDPRSLLCQGDVPGPGCHFSIPEAFSAALPNL
SDVVQLILLVDSNPFPFGYISNYTVSTKVASMAFQTQAGAQIPIRQLASERAITVKVPNN
SDQAAQDQYVPAGSTVIQPRASVSVVVTPENSNPEAGLHLQLTFTVLDEQYLPDEPEPFL
AAYLHSEPRPNEYNCSASKKISLEALAGGDHRPYTFFIAPGSRDLGASYHLNLSSHFRWS
ALAVSVGLYTSLCQYFSEEHMAWRSEGLVPLEETSPREAVCLTRHLTAFGASLFVPASRI
EFTFPEPASGINHVVLLTCAVCLLTYAVMAVILRKLDQLDVRRVRAIPFCGKGGRFKYEI
LVKTGWGRGSGTTAHVGIMLYGADGRSGHRHLDGDGAFQRNSLDVFQIATPHSLGRLWKI
RVWHDNKGLSPAWFLQHVIVRDLQSARSTFFLVNDWLSVEMEANGGLVEKEVLAASDAVL
WRFQRLLVAELQRGFFDKHVWLSMWDRPPRSRFTRVQRATCCVLLVGLFLGANAVWYGAV
GDSAHSQGPVSSLAPLSLDTVAVGLVSSLVVYPVYLAILFLFRMSRSKVAGGPSPTPAGP
QALDVDSCLDSSMLDSSMLAFPGLGGEAFAGQMKQDLFLEDSKSLVCWPSSEGTLSWPDL
LSDPSVMGSALQRLARGRMGLTPGPEEDSLSLVSPSSPAKYFSASDENLIRQILAEGAGS
LAPTQDTQGETDLLAGLCSAPGEKTQPAMLRSLGDTRLPSPGLTWEQPPPARLPRTGLVE
GLRKRLLPAWCAPLAHGLSLLLVAVAMGVSGWVGASFPPSVSVMWLLSSGSSFLASFLCW
EPLKVLLEALYFALVAKRLHPDEDDTLVESPAVTPVSERVPRVRPPHGFALFLAKEEARK
VKRLHRMLRGLLVYMFFLLVTLLANYGDTSCHNHAYRLQSAIKQELDSQAFLAITRSDEF
WPWMSHVLLPYIHGNQSRPELGPPRLRQVRLQEALCPQPPGSRNPACSAASSGFSTSDYG
VGWGSAALNSSEIWAYSAPDLLGVWSWGSCAVYDSGGYVQELGPSLEESRAQLGFLQLHN
WIDNRSRAVFVELTRYSPAVGLHAAVTLRLEFPAAGHAVAALSVRPFALRRLSAGLSLPL
LTSVSLLLFAVYFSVAEVRAWRREGRARATRAGTWARWLLVVLTAAAALVRLAQLGAADR
QWTRFLRRRPRRFTSFEQVAQLSAVARGLTASLLFLLLVKAAQQLRFVRQWSVFGKTLCR
ALPELAGAALGLVVLAAAYAQLAVLLVSSCVDSLRSAAQALLVLCPGTGVPALCPAESWR
LSPMLCTGLWALRLWGALRLGSVLLRWRYHTLRGELYRPAWEPQDYEMVELFLRRLRLWM
GFSKVKEFRHKVRFEGMEPLPSRSSRDSKASPDVPPPSGGSDASRPSTSSSQLEGLSLGL
GRPGPRELEPEPSRLHAVFEALLTQFDRLNATEDVYQLERRLQLHGRRSSAPLASQPPSP
SPGLRPVLPSRLARASRGIGLSTGPSRASLRAKNKIHPSSS

>Monodelphis domestica_PKD1(ENSMODP_20012)
MPRGQGPPLAAPSPHGHGGPRPPPAPAPAPARFAFCLCLGLCIGGLSAAPDPGCQPCGLD
CNCTPGPGGACSVNCSGRGLRGLGPELPIPPDVTALDLSDNFINTLETEFFENLSALTQL
DISNNKILTLEEGIFANLFNLSEINLSLNPFICDCNLSWFPSWVDEQKVSVVQPRETRCA
EPPRLADVPILSVSFSDGTCDLEYIACVQDNSSSAMTVVIFSAALDGEFTRNTCSAFCFS
FGQQYGGLSEEGRCFCGTARSPNASSGCLRFCPGLAAPPVACRVPFILHNVFPASLEASL
WGPGGPQPAGHPVVFNVSTPLPANNLRWDFGDGAPALIAGPAASHRFILPGHYNVTAVLT
LEVGTALLWTEVQVEAVPTELELLCPSWLQSNESLEIGVRNRGGTGLSATYSITAESEQP
AQVVHPLCPSNTDIFPGNGHCYRLVVEKAAWLQAQRHCLAWGGGDLAIVGSPEIQRFLVS
QVTRSLDVWIGFTALTGPGVPPHGEAFSLESCQNWLPGEPHPANAEHCVRLGPAGQCNTD
LCTATHSYVCEFQPTGIVSSADNFFVGDAGSDLPGPTVPVEERDFLSAPGRETVEVMIFP
GLEMQQKGFLTAAEFETQDLMQPVQMRLQVYRPVEGGIPENSSQPLCPSMDNQTWVPLDC
LPGEHWCPLANLCLPLDSPCSLSPCANDSSPEQDNHWSGHYSLWREFLFSLPAGPSSQYS
VSFSGKNISLLPGDLFSLQHDAGPGSLLRFLPRPEALPHQRFQPECLSANASTWLPSLPA
HFSEVPVPNGSTCALRLLFATEQVTRLLGQPSNPGLQHVGRYLFRASLDNGVSSHNLSCS
FHVLSPVAGLRVIHPMPQGGLFYVSTNWTYLVLKISSGANSTARRLGSNQSVPFEASCPL
GVARLTADCARETNDSWFALLELDGLGEDESLVEIVAENRVSLENISIQVKAEEPIRGLS
ATPNPQTRVLQSTLVRYSPVVEAGSDVVFKWTIDDKQSLTFYNVVFNVIYQSAAVFKLSL
TASNHVSNVTVNYNVTVEKMNKMRDLVVSEVPAIIPQNTTLQLGASVQVDSAVEVTFLWT
FGDGEQESGQFKPPYNESFLVPEPGVHQVLIEHNVTHTYHVPGDYNITVFVYNTLENLTQ
QVPLSVRASLPHVTVRTDSGALGVGHPITFMPHPLPSPTGILYTWDFGDGSPVVLQNQPE
VTHTYVSRGVYNISLTVNNTVSSVGARLSVRVFEEIRGLRVTSTAATEKGMAVVVNASVE
AGDNITWTFDMGDGTVLTGPEASVQYVYLKDENCTIQVTAANPVSSVFQVLPIHIFVLEV
LKIEPSSCIPEQPEVQLTAHVTGDYTHYVFDWTFGDGSSNATVYGHPTVMHNFTRSGVFP
LSLVLSSLVNKAHYFTSVCVEPEVSNITLQPERQFVKLGEEATLEVQAFPPFLYRYSWDF
GANDSARSGGTEASHTYRVPGIYLVTVTVSNNVSSDNDTAFVEVQEPLGITSIEVNSSHV
LELSQPYLFSVLGSGSPASYRWDLGDGQRQEGLRVIHAYNHTGSYTISVVGWNEVSRSEA
QLNVTVKRRIQGLSVNASRTVVPLNGSVSFTTTLEAGSDVHYSWVLCDRCTPILGSSTIS
YTFRSVGTFNIIVTAENEVSSLQDSIFIYVLQQIEGLQMLGGGEGGCFPTNRTLQLQAAV
RDGTNISYSWALQQDGGLSHAAHGKVFSLTVLEAGTYHVQLKAINMLGSAVVNRTLEFVE
EVGQLAASASPNPAAVNTSVNISAQISSGTSITYAWLLQEGVSVEAAEPFIVHSFSSPGL
WAVTVTAGNQLGSVNATVHVDVQEPVAGLTVGCGESGSRFVASGSLVYFWGDLELGSNVS
WSWELPDGPRSGQRIAAVFPHAGAFSIRLNASNAVSWTTASCNITVEDPIQGLELWASSR
VVEPGERVQFNIHLTAGSDVNYRLLISGGVTTALGEPHFSHSFPRVGDYMVTVQAENHVS
WEQVQVRITVLEAIGGLQIVGCCELGIPTGGERNFTARVQRGSRVSYAWYFSLQKVQGDS
LVILSGREVTYTPVAAGQLEIHLHAFNDLGSVNLTRTIEVQDLIQAVELHPESCFTNRSA
QFEAATTPSPRRVFYRWDFGDGSQTHVTATPSSNHTYLFPGDYTIKVNASNLVSFLVAKT
TVTVRVLECEEPEVEVALPTQVVMCRSQRSYLEAHINLRGCVTYQTEYHWKVYRAASCLH
YRRSAHVPLPGVDVSRPQLVVPRLALAVGDYCFVFVVSFGDTPLSRSIQANVTVTPGRLV
PIIDGGSYRVWSNARDLVLDGGKSYDPNLEDGDQTLLSFHWACVSSSKSHPGGCPLNFGP
RGSSIITIPKERLEAGVEYTFNLTVWKAGRKEEVTNQTVLIRNGLVPIVSLECVSCKAQS
VYEVSKSSYVYLEGTCHNCSSGSKRGRWAAQTFSNKSLVLDESTTSTGSSGMRLVLRRGV
LRDGEGYTFTLTVLGCSGEEEGFASIDLFPNRPPIGGSCRLFPHEAVKALTTKVHFECTG
WRDTEDENAPLVYSLLMRRCRQGYCEEFCIYKGSLSAYGAVLPPGFKTHFTVDLSVVVQD
QLGAAVVALNKSLLITLPEPSPSFHCLTHWLYSLTETVLPGLVKQADPQHVIEYSLALIS
VLNEYEQVTSSEEEASHERQLRGLMRKNITEMLVSLRVNTVDDIQQISAALAQCTVASKE
FVCPSCLRKTLNKLENMMAILQNETTQGTVTPTAIADNILNITGDLIHLVNSDPQGLVPT
ELCAAGGLMASRAYNLSSDLMRILMKSRVLNEEPLTLAGEEIVAQGKRSDPFSLLCYENT
SDCQFSIPPAFNSTFSDLTDVVQLIFLVDSNPFPFGYISNYTVSTKVASMAFQTQAGAQI
PIERLGSEKAITVKVSNNTSGGGGGDRVLSTSTAIIQPRTSVSAIIAPENHNPEAGLHFQ
LTYTVLNERYLSEEPEPFLAVYLHSAPQPNEYNCTASKKIGLKALAGGDHRPYTFFISPG
TDDTTASYYLNMTSHFHWSEVEVTVGLYTSLCQYFSEKEMMWKTEGIVPLEETSPSQAVC
LTRHLTAFGASLFVPPSSIQFIFPEPAPGINYIVLLTCAVCLATYVVTALIVHKLDLMDV
SRVSIIPFCGKNGRFKYEILVKTGWGQGSGTTAHVGITLYGADGRSGHRHLDGESAFHRN
SLDIFQIATQRSLGSVWKIRVWHDNKGLSPAWFLQHIIVRDLQTGRSAFFLVNDWLSVET
EDNGGLVEKEVLAASDATLRRFPRLLTAELQRGFFEKHIWLSLWDRPPRSRFTRVQRATC
CALLICLFLGANAVWYGVVGDASTPPSHPEPLIPLSVDTVAVGLVSSVVVYPLYLVILFL
FRMSRSKVSVSPDRSPAGQQMLDIDNYLETSVLDSSFLTLSGLHAEAFSGQTKTDLFLDD
SKSLMHWQSSDGTLSWPDLLSDPSIMGNTLQRLVRARAGNPPGLETMEEDGLSLGSPPSQ
TKYFSTSDEDLIRQILAEGASSIAPARDTHLETDLLTGLSGTLGAKTEALMLQRLNEKGL
PPAAPTQELVQSAKFTRGGLAEGLRKRLLPPWCAPLAHGLSLLLVLVAVGISGWIGTNFT
SSVGVMWLISGIFSFLSSFLFWEPLKVLLEALYFSLVAKRLHPEEDDTLVECPAVEPVCE
RIPRVRPPQGFALFQAKEEARKVKLLHRMLKNFLVYMLFLLVTLLTNYGDASSHTHAYRL
QSSIKQELDSKAFLGITRSDEFWGWMSRVLLPYVHGNQSALELGPPRLRQVRLQEGLCPD
ALGSVRRVCATSSSFSTKDYEVGWESSSPNGTRAWAYSAPDLAGVWYWGYFSVYDSGGYV
QELGVSLEESRELLGFLQRHNWIDNMSRAIFVELTQYSPAVGLHAAVTLRLEFPVSGRAL
TAISVRPFPLQRLSAGVTLQLLMMVFLMLFVVYFVVAEALAMQKEGQAYLVRAGAWGQWL
LILLTTATVLIHLSQLSLADQQWGRYLKRRPHHFTSFYQVAQLSSAFASLAASLLFLLMI
KAAQQLRFIRQWSVFGKTLYRSMRELVAAGLALLVLAVAYTQLGFMLFSSCSDSLRSMGW
DLFLLCPAGGDPHVCPSEPWRLSPLLCTSLMVLQLWGALRLGAVVLRRRYHALRGELYRP
AWEPQDYEMVELFLRRLRLWMGFSKVKEFRHKVRFEGMEPLPSRSSSDSKSSQDVSPPSA
GSDTSRPSTSSSQLDGMSLLMGRAGARGDPEPEPSRLLSVFEALLAQFDRLNQATEDVYQ
LERRLQGIQGWRSRDHLASPPWAPGPPIPSPSPGPPAGNQGTLPARIARASRGIGMAATQ
ASSGSPLVRASIRAKNRIHPSLT

>Gallus gallus_PKD1(ENSGALP_9154)
QGLEFIGNKQRLISEISILRDLSRNKISALDVQMFRSLTSLAKLDISHNKISTLEEGIFD
NLFNLSEINLSWNPFFCDCKLSWLPRWVEDRKVTVLQAADTRCAHPPGVANLSLFSVSFV
NATCGAQYVTCLTSNHTDEAELVILFTSSHPGNLTEETCSALCYADDQEYGGFSPQGQCL
CGTAHEPNSSSSCLLFCTEHSSGQACGGPSLIHFPFQAQLSVSFIGLKPRYSLHEAVLFN
VSIPIAVSTLIWEFGDQTEVLNTTGNAAVHTYALPGQYNVTATLFVGTKVSYVQAEIEVV
ASPQQLELQCPSLIKTNESLDIRIRNRGGTGLTVLYGITAESGEPGRAVHPMCPHDGLVF
PGNNHCYQLVVEKAEWLEAQQHCQEHGNGELAFVSSPEIQSFLVTHVIRRSLDVWIGFND
FASSEAQQRGEGFNIESCQNWLPGEPHPSNADHCVRMGPTGQCNTDLCMAKHSYVCEFKP
KGVLLNAENFFVGDPVFDTHVAAKNVIEDTLSSPLQAVEVMVFPELAFRHEGYLSALEFV
TQELHQPIQMRFQVHRPIDGKEYQEGQNATEPFPTSQDDGNYTLVECPPGFQWCHLTNLC
SSVNNCCNAMECTNSSFASSPIPASPQHKGSQLSYELVKEFLFTIPAGPSAPYLVTFSKE
DVFVRAKDVLSIQHNAGMGSFLQCQPSTTSPFRTNYFSTNSSDWALGLPASSIGATWIHN
TVCSLRVLYAKEQLVPIISPQNAGLAHPGLYTVRASVDNGIFSANLSCNFWVTSQVSGLR
VVHPAPQGGKVYVPSDHITLVVKISSGMNATARWLGDNHTFPFEEACPLTIAPLTSDCAR
ENNDTWFAVLSLSGLKEGASTHTLVAENAISSQNITITIKVEQPIRGLRATPDPESRVLL
NTRVSYVPVMEAGSDVTFRWTVDDKPSFTFYNVVFNVIYQSPAVYKLSLTASNHVSNFTV
NYNVTVEMMNKMKNLTVLGIPPVLPQNSTVEFTARVQVDSAVDAMFLWDFGDGIQETYQF
TPPYNKSFLVPDPSVHEVIIEHNVSHVYEYPGDYILVVQVSNQFENLTCLTPVRVHSYLV
DVQIETVKDVLVVNRSVTFRAIPLPSPYGVLYTWDFGDGSSLVTESQSTVTYSYSSRGVY
NISVSANNTINSVETVECYQVFEEITGLHVAADEVAEVGATVTLNASVQTGDSITWIFDM
GDGTVLRSQVPVVEHVYTKDINCTVNVTAVNPVNSVSQTIPVWIFVLEVLRIDPTSCILE
HPDVQLTAYVTGNPDEYIFDWTFGDGSSNVTVSGDPVVMHNFTRSGTFPLSLTLSSRFNK
AHYFTSVCVEPEIVNVTLLPSKQFVRLGEECSFQVSAVPLYQYRYRWDFGNNESTRSSGT
EVSYNYKSTGVFLVTVTVSNNVSFNNDTAFVEVQEPVGVAKIEYNGTKVLELNQIYLFSA
SMNGTKVNYFWDFGDGITQPGQITTHSYNNTGHYTISVTGQNDVSTNETRVDVTVKRRLH
GITINASRTIVPLNGSVSFVATLVAGSAIRYSWILCDRCTPIQGSSTISYTFRSVGTFNV
IVTAENEISSLQDSIYVYVLEQIEGLQVASSDLVEDLYFPTNKTLHLHAVVREGTNISYS
WIAQKDGNAVQTATGKTFSLNVLEAGNYTVYLKATNMLGSTTANKTLEFIESLGLLKPYA
FPNPVAVNASVNISATITSGTGIVYVWYLEDGLSPVTSESFIIHSFQSPGAMEVVIGAEN
KLDSTNATISVYVEEVIEELSIGTAELDCRYVSSGSTVVFEGELQKGTEVTWLWEVPNGT
LTGQSVAVMFPTAGFYTVYLNASNDISWAVASRNISVLDRIQGLEVIASKKVVEPGEQVT
FVIRMSSGTSVSYLVSISGDYSVVLNGSKYTHEFTKSGDYLVTVTVQNQISIAHAQVLIS
VLEAVRDIRLLNCCERGIPTGTEKSFSAQVGSGSRVLFSWQFSLWKERGRSVVTAAGESV
SYTPEAAGLLEIHLRAFNDLGGINITRTIQVQDPILQVSLTASNAFVNRTALFEAAVIPN
GRGVEFLWTFGDGSSTQMTRVAVANYSYLSPGDYLVEVNATNLISFFVAHLTVTVKVLEC
EEPEVELALPPQVVMKRSQRNYLEAQLDLRGCIKYQTEHLWEIYRAPSCLHLDDSSRIHL
PNVDVNRPQLVIPKLALEVGNYCFVFIVSFGDTPLSKSIFANVTMIPSKLVPIIDGGSYR
VWSNTQDLILDGEKSYDPNLDDGEQTPLFYQWSCTFSSKSSAAGCSLNFSANGGNVTIPK
AVLEADVEYTFNLTVWKKGMNPEATNQTVFIKRGGVPIVSLECVSCKAQSVYEVSKSSYV
YLEGTCQNCHNDSKIGRWAAHSFKNKSLILDKKTTSTGDTGMNLVLRQGALKDGEGYTFT
LHITDLTTGEEGFASIDLLPNQPPIDGSCQLSPKGPLRALMAKVHFECTGWRDTESAEDP
LVYILLASRHRAGHYHEFCVYKGSRAEHSAFLPPGFHESGFVVSVSVLVQDQLGATVVAI
NQSMEIGLPEGFPSLSYWLYNQTDTVLQGLVKQGDPQQVIEYSLALITILNEYERSMLLE
PETGNEFELRTWTRNNITETLNSLNVNTVDDIQQISAALAQCTVVSKELVCKSCLTRTLN
KLESMMTILQGEMTQGTVTPTGIADNILNITGDLIHLVNTVSQESKPQELLADSHNLLLA
PKAYNLSSSLMRILMKSRVLNEEPLELVGGEIKATGKRSDPFNLLCYENTPNCQFSIPQA
FNTTLSNLTDVIQVMFQVDSNPFPFGYINNYTVSTKVASMEFQTYNGVQIPIGSLDSERA
ITVMVSNNTDADNLSAGTEVIEARTSVNLIVTMENNNREAGLHFRLTYKVLNDRYVASEP
EPFIMAYLHHEPEPNEHNCTASKKISLEALSGSDHKLYTFFTSPLTDDTIQKYYLNITNH
FSWSPVEVTLGLYTSLCQYFSEQEKRWKTEGIIPLEETRPDQAVCLTQHLTAFGASLFVP
PNSVQFIFPAPGSGLNYIVLLTCAVCFVTYSVAALIVHKLDMIDINRVGVIPFCGKNGLY
KYEILVKTGWGRGSGTTAHVGIALYGVDNKSGHRHLDGENAFHRNSLDVFQIATERNLGS
IWRIRIWHDNKGLSPSWYLQHVIVRDLQSSKSYFFLVNDWLSVESEENDGMVEKEVYAAS
ETELRSFSRIFIAELQRGFFEKHVWLSMWDRPPRSRFTRVQRATCCSLLIFLFLCANAVW
YGVVGNVHLSSGAVSNLIPVNVDTVAVGLVSSVVVYPLYLVILFLFRMARAKVSINHTVT
HSDQQSLEIDNYLDSSVLDSSFPTFPGLRAEQAFSEQTKTDLFLEDSKSLIRWPSSEALL
SWPDLLSDPSIMGNTIQKLKRGRASRHLGLEAPLATEEDNLSLGVHQGQPRYFSASDEDL
IRQILADGASGISHSQDLGPYMRAETDLISGLSSVFGEKVETVMMQKLNDKGQSMAAPPR
EVSRSAKSTWTVADQTFRKRLLPSWCSYLAHGISFFLFATSTGVSVWIGVGFSSSVALMW
LISGIFSFLASFLVWEPLKVLLEALYFSLVAKRLHPEEDDTLVEHPFVEHVSEKISKVRP
PQGFALFQAKEEARKVKLLHRMLKNFLIYMMFLLVILLTNYGDATRNSRAFLLQSSIKQQ
LGSSEFLHIKRSDQFWVWMSQVFLPYLYNNQSGQESYSTTLGVARLRQLRLQEVLLPPEI
EKNCIDSHSFSTADYAAGWERAAVNVTTAWSYSPPDLTGVWYWGYISFYDSGGYIQELGT
SLEEGRAQLNYLQQHTWIDNMSRVVFVELMQYNPSVDLHAAITLQLEFLGAGQAVTTVTI
SPFPLLRLSSGVTLQLLMMVFLMMFVVYFVVSESLSIKKEGRAYFTLWGNYGQWVFILLT
TCTVVVHLSQATLADQQWLKYLNNRKVFTNFYQVAFLNTVFSTLAASLLFLLIVQAAQQL
RFVRQWSVFGKTFQKSMKELTAAGLAFVVLILAYAQLGFLLFSSSSESFRSVGSSLLLLI
AMVRGGVSLYPCPPDSSGLYYLFCTSYIILEVWIVLRLFTVVLVYSYREMHFEMYRPAFE
PQDYEMVELFVRRLKMWMGFSKAKEFRHKVRFEGMEPLPSRDSSDSKSIRGPTPSAASDS
SRASTSSSQLDGLSLVLSTRDSLEVDADLQRLLSLFEMLLAQFDRVNQVTEDVYRIEHQL
QGSQSRRSRRRYCAGNTERGPSPETRSSVPSHLIRASRGISGAASVLPPHKAHSTLAPAV
KKKRPLRAKNRVHPTVK

>Taeniopygia guttata_PKD1(ENSTGUP_6601)
LEDGIFDNLFNLSEINLSWNPFVCDCKLSWLPRWVEERKVRVLEASDTRCAHPPEVANLS
LFDVLFLNATCGAQYITCLTGNYTEEAELIILFTSVHPGNLSEETCSALCYSQEQEYGGF
SPQGQCVCGAAHETNSSSGCLPFCTEHLSGQGCGGPSLVPLPFQAQLPVSFTGLQPRYSL
HQPVLFNVSIPIAASTLLWEFGDRSEVLNTTAHTAVHSYALPGRYNVTATLLVGSRLLQE
QAEIEVVASPQQLELQCPSLVVANESLDIRIRNRGGTGLAVLYGITAEPGQLGRAVHPMC
PPEGLVFPGNNHCYQLVVEKAEWLEAQRHCQELGDGDLAFVSSPDIQSFLVAHVIRSLDV
WIGFNDFASSGAQQRGEGFNLESCQNWLPGEPHPSNADHCVRMGPTGQCNTDLCMAKHSY
VCEYKPPGVLLNAENFFEGEAELGTEEAVRSVSEAVLADPWQAEEVLEFPELAFRHQGFL
TALEFVTQELHQPVQVRFQVWFCSFEEIKPWGSGLEKITEEKPLSMPEESWCPLTSLCSS
HNSCCNGTECANSSFGSSPAPGAPQPSDSQPSRELLKELLFTVPAGPSSQYQVTFRKENI
FVRAGDVFSIQHSAASGSFLRCRRRAASAGRGNCSAWAAGSCHSPAGAPRANSSACSLRV
RYAEEQLVPVLSPHNAGLERPGGYAVRASVGNGLFSANLSCGFRVASRVSGLRVLHPAPQ
GSRLYLPTNHTALLLKLSSGVNATASCLGDNRTVPFVATCPPALAALCARETNDTWFAVL
QLGGLGQGLSTHVLVAENSVSSQNITVTVKVEEPIRGLRATPDPESRVLLNTRVSYIPVM
EAGSDVTFRWTVDDKPSFTFYNVVFNVIYQSPAVYKLSLTASNHVSNFTVNYNVTVEMMN
RMRNLSVVGALPVVPQNSSVEFSARVHVDSAVEALFLWDFGDGVQETYLFKPPYNKSFLV
PDPSVHEVVIEHNVSHIYQDPGEYALMVVVSNQYENLTHLSPVQVHSYLVDVKVEAEEDV
LVVGRPVTFRAAPLPSPYGVVYTWDFGDGSSLLTDTQPSVTYSYPRRGVYNVTVTANNTV
SSVETVECYQVFEEVTGLRVSTAEAAEQGAAVTINASVETGDSITWIFDMGDGTVLRSQV
PVVEHVYIKDINCTVNVTAVNPVNSVSQAVPVRIFVLEILKIEPTSCILEHPDVQLTAYV
TGNPEEYIFDWTFGDGSSNVTVSGDPVVVHNFTRSGTFPLTLTLSSSFNKANYFTSVCVE
PEILNVTLLPSKRFVRLGEESSFQVSAVPPYQYRYRWDFGNNESTRSSGTEVIYTYKNTG
VFLVTVTVSNNVSFNNDTAFVEVQEPVGVAKIEYNGTDVLELNQIYLFSASMNGTKVSYC
WDFGDGTVQPGQVATHSYNSTGHYSITVMGQNDVSSNETTIDIAVKRRLFGLTVNASRTV
VPLNGSVSFVATLVAGTAIRYSWILCDRCTPIQGSSTISYTFRSVGTFNVIVTAENKISS
LQDSIYVYVLEQIEGLQVASTDLVEDLYFPTNKTLHLQAVVREGTNISYSWVVQRDGNAV
QTFTGKTFPLSILEAGNYTVYLKATNMLGCATANRTLEFMESLGVLKPYAFPNPAAINAS
VNISATITSGTGVTYVWYLEDGSSPATSEPFILHSFQSSGMIEVIVGAENKLNSTNATVS
VCVEEVIEGLTIGTAELDCRYVSSGSTVVFEGELQRGTEVTWLWQVPNGTLSGQSVAVTF
PTAGLYTVHLNASNHISWALASRNISVLDRIQGLEVVASKKVVEPGEQVTFEIRMLSGTS
VSYLVSISGDYSVVLNGSRYNHEFTKSGDYLVTVTVQNQISIAHAQVLISVLEPIQDLRL
LNCCEEGIPTGTEKSFSARVGSGSRVSFSWQFCLWKERGRSVVAASGERVSYAPEAAGLL
EIHLTAFNDLGSVNITRTMQVQDPIVQVSLSATNAFVNRTALFEAVVVPSSRSVEFLWSF
GDGSSTQTTRVAVANYSYLSPGDYLVEVNATNLISFFIAQLTVTVKVLECEEPEVELALP
PQVVMKRSQRNYLEAQIDLRGCIKYQTEHLWEIYRAPSCMNLDDSSRIRLPNVDVNRPQL
VIPKLGLEVGSYCFMFIVSFGDTPLSKSIFANVTVIPSKLVPIIDGGSYRVWSNTQDLVL
DGEKSYDPNLDDGEQTPLLYEWSCTSSSKSSAAGCSLNFSAKEGIVTISKALLEADVEYT
FDLTVRKEGMSPEATNQTVFIKRGGVPIVSLECVSCKAQSVYEVSKSSYVYLEGTCQNCH
NDSKLGRWAAHSFKNKSLILDKTTTSTGDTGMNLVLRPGALRDGEGYTFTLHITDLTTGE
EGFASIDLLPNQPPVGGSCRLSPEGPLRALVTKVHFECAGWRDTEDAEGPLVFILLASRH
RPGHFHEFCVYKGSRAEHGAFLPPGFHESGFQVSVAVLVQDQLGATVVAVNRSMEIGLPE
GFPSLSHWLYNQTDTVLQGLVKQGDPQQVIEYSLALITILNEYERSVLLEPEAGQEFELR
TWTRNNITETLNALKVNTVDDIQQISAALAQCTVVSKELVCKSCLTRTLNKLETMMTILQ
GETTQGTVTPTGIADNILNITGDLIHLVNTVSQESKPQELLADSHNLLLAPKAYNLSSSL
MRILMKSRVLNEEPLELVGGEIKATGKRSDPFNLLCYENTPNCQFSIPQAFNSTLSNLTD
VIQVMFQVDSNPFPFGYISNYTVSTKVASMEFQTHNGVQIPIGSLDSEKAITVMVSNSTE
PENLVAGTEVIEARTSVNLIVIMESNNREAGLHFQLTYRVLNEHYLASEPEPFIMAYLHH
EPEPNEHNCSASKRISLDALAGSDHKLYTFFTSPRTDDPIQKYYLNITNHFSWSAVEVTL
GLYTSLCQYFSEQEKRWKTEGIVPLEETRPDQAVCLTQHLTAFGASLFVPPNSVQFIFPA
PGPGLNYIVLLTCAVCFVTYSVAALIVHKLDVIDTNRVGVIPFCGKNGMYKYEILVKTGW
GRGSGTTAHVGIALYGVDNKSGHRHLDGDNAFHRNSLDVFQIATERSLGSVWRIRIWHDN
KGLSPSWYLQHVIVRDLQSSKSYFFLVNDWLSVESEDNDGLVEREVFAASESELRSFWRI
FVAELQRGFFEKHVWLSLWDRPPRSRFTRVQRATCCCLLIFLFLCANAVWYGVVGSVHLS
NVAISSLIPVSVDTVAVGLVSSVVVYPLYLVILFLFRMARGKVSISHTVTHSDQQSLEID
NYLDSSILDSSFPTFPGLQAEAFSEQTKTDLFLEDSKSLVPWPSSEALLSWPDLLSDPSI
MDNTIQKLKRGRASRHLGLEAPLAAEEDALSLGIHQGQPRYFSASALNVIRQFLTDGHTG
LFQGLGPYVRAETDLISGLSSVFGEKVETVMMQRLNDKGQSVAPPPREVSRSAKSTWTGT
RATFRKRLLPPWCSLLAHGISLLLLATAAGVSVWIGVGFSSSVALMWLISGIFSFLASFL
LWEPLKVLLEALYFSLVAKRLHPEEDDTLVEQPCVEHVSERISKVRPPQGFALFQAKEEA
RKVKLLHRMLKNFLIYMMFLLVVLLTNYGDASRTSRAFLLQSSIKQQLGSSDFLLIKRSD
QFWVWMSQVFLPYLYNNGSGQESHSTTLGTARLRQLRLRGAECPGHPAGHGHCTDQHSFA
TADYEVGWESTAGNGTAAWAHSAPDLAGIWYWGYISFYDSSGYVQELGPSLEQSRAQLEF
LQQHTWIDNMSRAVFVELLQYNPSVDLHVALTLRLEFPGAGQAMAAVTVSPFPLLRLSGG
VTLQLLMMVFLMLFVVYFVVSESLAIKKEGRAYFTLWGNYSQWVFILLTTCTVLVHLSQA
TLADQQWLRYLSNRRGFTNFYQVAFLSSVFSSLAASLLFLLTVQAAQQLRFVRQWSVFGK
TFQKSMKELMAAGVAFALLLLAYAQLGFLLFSSSSESFRSVGSSLLLLLALLRGSASLRP
CLPEASGLCCLFCTSYVVLEVWIVLRLLAAVLIHSYREMHFELYRPAFEPQDYEMVELFV
RRLKMWMGFSKAKEVR

>Anolis carolinensis_PKD1(ENSACAP_9036)
MDCPSGSHWCQLTNSCLPLGGCCNKFESCANSSMASTPSPIAHRCPNPPSMVQVQESLFI
VPPGPSMMYLLLFKNKDVSIGPNDTLSIQHDAGPGAFLLCHRNRVPSSPTSYFSWNSSAW
EMDFHPSFHASKWHNDSECEFRLLCTTEETSPIIRKQNFGIPSPGFYTLRATISNTVFAT
NVSCDFGVESPISGLRVVSPPEQGGILYVEANHTFLVVKISSGGANTTVGWIGGNRSTLF
EKTCPVSVVKCGPKTDDTWFAVVSLEGIAENGSTVVLQAENTVSTQNLTVVVKAEEGIRG
LRATPDPESRILLNSRVTYVPRMDAGSEVTFRWTVDDKPSFTFYNEVFHVIYQVPAIYKL
SLTASNHVSNVTVDYNITVEKMNRMKDLLVSEVPQRAPQNGTLDLAASVRVDSAVKATFL
WDFGDGNNASSQFQPPYNDSFLVPDPTIHQVVIAHNVSHAYQEPGEYTLTVVVYNEFENL
TYSVPIHIYSYLMDLTMEADTDVLVAGRPVTFKAHPLPSGFGVSYVWDFGDDSMVYVESQ
PTIVHTYNTKGIYNVSLRANNTISTMETFWCYRVFEEITGLHVTMEEAIEVLMPLEISAS
SETGDNITWIFDLGDGTVVETSEASVNHSYLKEMNVTVNVTAMNPVNSVSRAVPIQVFLL
MVLKFEPSACIVEHPDVQLTAYVSGNAEDYVFDWMFGDGSPNVTVYGDPTVRHNFTRCGI
FSLSLAISSKVDKIHYYTVVCVEPEVTNVTLFARSSFVMLGNESKFQVTALPPYPYRYHW
DFGTNDSLKFGGTEVSYTYKAPGIYLVVVTVSNNVSFNNDSALVEVQEPVGVARIESNAS
KVLEVNQVYLFSANVSGTKVRYLWDFGDGTTQLGKFITHSYNKSGIYAVSLKAWNEVSFR
EARVNVTVKRRLQGLSINASRTVVPLNGSVSFTATLLAGTAIRYSWILCDRCTPILGSST
ISYTFRSIGTFNVIVTAENEIGCLQDSIFIYVLQQIEGLQIVGAGLLDNTYFPTNKTLQL
QANIRDGTNISYSWAVVKESHSVQTFTGKTFSLVILDAGVYIVHLKATNMLGTLAVNKTI
EFIEPVGVLKLVAFPNPVAVNASINVSAAISAGTGLEYTWYLENEVPVTTVFSSITHFFQ
SPGAKEVTVEAENKLGSTNATLMVFVQEPVTGLRIRTLRPNCTYIESGSVVNFSGELESG
SDVSWVWKMPNGTISGQRVALTFPTPGFSSVCLNASNDVSWEGACHNLTVQDAIRDLRLS
VSKRVLEPGEEASFSIGMSSGSSVRYEVSIAGNQSMVLNASNFSYTFTRVGDYVVQVTAE
NYVSVVHTEVHIVVLEAVRGLRLVDCCEQGTPTGVERRFAAEVEAGSRVSYQWRITLTED
EGRSQVATLEGPSISYMPEVAGRLDVHLQASNLLGGLNVTVVIQVQDLITQLSLLPVKPF
ANRTTSFTVSVRPNARQVGFLWRFGDDSPVLRTDVASASHTYLQPGDYLVEVNATNLISS
SFARLTVTVRVLECEEPEAELALPAQVVMKRSQKNYLEAQINLRGCTSYKTAYLWEIYRA
PSCLQMGSADKVHLPHVDATRPQLVIPKLALDLGNYCFKFLVSFGDTPLSKSTFANVTVL
PNKLVPIIEGGSYRVWSNTRDLVLDGGKSYDPNLEDGEQTPLLYSWSCVSSSKSPSSKCA
LDFSARGGVVTVSRAILEADVEYTFALSVWKEAMSPESTNQTVFLKRGTVPIVSLECVSC
KAQSVYAVSRSSYVYLEGTCLNCQNNSKMGKWAAQSFKNKTLPLDRSTTSTGDAGMNLVL
RPWALKDGEGYTFTLRITDLASGETGFASMDLLPNQPPFGGSCWLSPMGPLQALTAKVHF
ECTGWRDTENEGTPLVYVLLATRCRSGHCEEFWVYKGSHAEHAAFLPPGFQENGASVSVS
VLVQDQLGATVVAFNSSLAITLPVVPEGFGSLPQWLSNQTKVVLQGLVKQGDPQQVIEFT
LALITILNEVGRSHPASPGAEIEGDDRLRAWMRRNITETLVSLNVNTVDDIQQIAAVLAQ
CTVANKAFVCRDCLKKTLEKLESMMDILQGETMQGTMTPTAIADNILNIMGDLIHLVNTA
SRELVPQELGSGQSPVEVASKAYALSSDLMRILMRSRVLNEEPLELAGTNITATGKRADP
LGLLCYDQDDPECQFSLPPAFNTTFSDLSDVVQVMIRVDYNPFPFGFVANHSVSSEVASL
EFQSHNGTEIPVGALEPEKAITVMVADPREKDITAGTVVIEEAGSVSAALRVESRDPEAG
LYFQVTFSVLNDRYVSSEQQPSIAVCFFPAPEPGIVPNCTDTKEIYLEDMNRRPEGDHRQ
YTFFVSPVTEEAEKEYFFNITNHFLWSPVEVTLGLYGSLCQYFSPEEIRWKTEGLAPLEG
TTPERAVCLTRHLTAFGASLFVPPHSLQFLRPPPGPGFNYIVLLTCAVCLVTYFVAAVIV
HKLDLIDINRVGVIPFCGKNGLYKYEILVKTGWGKGSGTTAHVGITLYGMDSKSGHRHLD
GENAFRRNGLDIFQVATERSLGSLWKIRIWHDNKAYPTFWIIQHIFVPRIANKVLLLYYY
NPGLQINFEANHGPSRVKSLANMMATTYWSLRQMMGQYDDHDPLLDSSFENWWTSMVVVA
CCWASLWVKSLANMIAMTYWSLRPLMGQYGHHDPLVGSSFENWWTSIVVMACCWASLWVK
LLTLFQVSISQSLVHSDQQSLEIDNYLDSSLLESSFLTFPGLRTELLGKDAGGGKSCNYV
DSQKESEQLGAQDLVRQTAPSQAAIELESKSGQGRAGPSEVPEYIRRNTISGKQPVLFLR
VLCECTLMETSKVGGMANPITQSSVQTHLLSTRCKKTEETLSTLNTNRMDDNGQPVTDKR
AQWSEQSSVRVFGKKVMSGRRTALSWWKRRKERGLSLTLEVPGVGYHGWRGQGGGFRDGV
EESSDETDFCGWEEIRKDHNALFPEKGARRSRKEQRGRIWSGPRSGMVVAVVVEIERSPR
DWASGPTLGLWHSCRTFAPTFRDLVLAARLLLMTVVTRARRASKRLVTKRLSARIEKALG
VEIFIRCQRLDGLWPSLSLKLFIYLRHHIRLSNILPVRLCWITSVQRVLGGDDASDPKEK
CASIARGFDTTNYAVGWKKGNHSEPWKYSPPDIAGGWYWGYLSFYDSGGYVQELGTTMEE
SRARLQRLRQNNWISNVSRAVFVELTQFNPGLGLHAVVTLRLEFPMAGHAMPAVAVAPLP
LLPHSRGVTTQLLMMVILMAVVVYLVVSECLSIKKLGRAYFGFLGSYGQWLLILATASAV
VVHLSQASLADRQWTQYLKDKGAFTSFYEVASLQDAFACLAAVLLFLLTVKVSQQLRFIR
QWSTFGKTLQRSMKELFAAVVVFAILTAAYAQLGFLLFSSQSEAFCSVSRSFRLLFAAHR
SSTPMRLDLPGPPGLSHLFYATFLVLELWVVGRLFAAVLIHHYRQTRFEMYRPAFESQDY
EMVELFVRRLKMWMGFSKAKEFRHKVRFEGMEPLPSPSSSQDSRSLLVPTPSATSDTSRA
SSSSSSVQLDGLSLAPGPRGSCEVDAEVQRLLALLETLLGRFDRVNAATEEVARLESQSQ
PLRGNASPLPSNGINFPAAPHPTAAPAPLRIVRSDQGLLLAPCKTQTLLVPAVRRKKPLG
AKNRVHPAGK

>Xenopus tropicalis_PKD1(ENSXETP_52824)
DLSYNSIKSLDKELFENLHFLRELNISNNQISTLEEGIFSSLLNLSVIDLSDNPWLCDCH
LYWLPCWVRDVGVSVQQENSTLCDQPSALAAQPLLNLSFPGSCAADFIACPDNSSIHNES
VLIFTPYNSASVNNVSDEFCSALCFVDQYTHGAVGPQNGCLCGCALASNTSSSCHALCEA
SSSLSNCNLTIVHDVFRTQLSASVNHFKETYSLVEAVELQVEAPSPITPCHWDFGDQTVN
STESNMVHRYALPGLYNVTVTLVVGDRDVLVNNKVHVVGLPEELQLMCPSLVRTNETLTV
NVSSRGGTELTVEYNVTSEGGEEVPLVFYMCPPGSIRFSGNNHCYQLVSEKAGWFEARKT
CEDLGHGNLAIVRSDDVRNFLSNMISPQLPMDLWIGFNDSGRNFTLESCQNWLPGQPEPS
QADRCVMMGRSGVCNTDLCSSKHSYVCEYKPQDLQLNADYFVLGSLSGESRPLKNLQRSN
NLSLPYGNEVEVLVFPGVQFAQDVYLSALELEAKELQRSVQMKFQVYLQDDNHGELECNA
DTPTSLPIIQDVKQSQSECEEGHETSNSTNSSLPLGSGCAPAKEIEYTTPASPQPGIGSP
SYVLQRELNLVIPPGNATNYLALFDDLRIQVSPNHLFVVQHDGPDGGFLYCYPNKSGVRM
FSLSQWISCIPRRSGQMDSNFCSMRLTGTSEVKAPILDPNPGLAWPGHYVVTAFFSNQEF
KANRSCTFQVASPVSGLQAVYPVSQQDIIYLPSNNTVLVLKILSGSNATASWSGSNESWS
FQPTCPPSIAAFTDVCTEGEDVWYSEINLDGRGKNFLDVVIIAQNMINSQNLNVSVKIEE
PIRGLSASPFPQTRVLEGMMSLSHPVINVASVEAGTNVSFKWTVDDKPSFTYHNVVFNVI
YQSAAVYKLTLSASNHVSNASVNYNVTVEKMNPMKDLMVFGVPLIATQNALLELSAIILV
DSAVDATFNWTFGDGTNQVYQYSPPYNQSFSVPNPSVYQVLIENNVTHAYREAVWTGAYN
ITVCVSNMHENRSQLIPLQVQSILTNLSITVEAVLVSGQQAIFQAEVEPSAFEVQYDWDF
GDGTEEFNVSDPTVNHTYLSRGAYSVKVTARNYLSEISSSEIFQVFEEITGLNVSSDEPT
ERGLPTIVNASVETGDNITWIFSMGDGKVQVGIEPVIKYVFPKDGNYTVNVTATNPVNSV
FETLKVHVYVLQVVRIEPSGCILESPNVTLTAEVTGDYENYTFNWTFGNGSDIITTLGVS
SVEYNFSTSGVFPLSLIVSSQVNKAYYYTNVCVEPEIVNVTLLPVSQFVGLGNESYFQVT
VFPFYQYRYIWDFGTNCSKQSSGTEARHRYKVPGVYVVTVSVFNNVSSNNDTALVEVQEP
VETVLITYNGTKDLELNQTYQFTAVSNGTKVRHNWDFGDGNTQEGQIVTQVYKSTGSFTV
SLNSCNNVSSSKTSLNVTVMSRIQGLTMSANWTVVPLNSSVSFTAFLLEGDNVRYSWILC
DRCTPMLGSSTIIYTFRSVGTFNVSVTAENNVSAQQFSVVIYVLEAIEGLHIVTSDLVND
CCFPTNRSLLLQADVVEGTNISYSWIILRNDRAIQSGSGKNYQFTSIEADVYTIVLKATN
MLGNSTISKHIEFIETIGQMKLLAFPNPSAVNASVNISMVLSSGSGVTYSWYLEESVIWF
TYESSVLYRFNSPGVKEVFAVANNTLGLVNSTILIFVQEPVEGVSISVMDHRGDHIPTGT
ILCLNGNVQKGTKVSWSWDLPEGTKEGRRVTVPFTEAGFYVITLNASNDVSWETESKNII
VQDRIQGLKLLVSKKVVEPGEKVNFTIDMTAGSSVTYKLTINGDYSILLNSTTYTHEFTK
IGGYPVTVVAHNEVSEERDTVMISVLEAIRDLTIVNCCEGAMPVGVERSFIAEVSNGSLV
AYTWQFDLQGHSTTSLAGKNVTYTPRAAGLLTIHLSALNDLGGLNISKIIRVQEMIEEGR
LKPVNTFVNRSVTFEAIVLPSSKDVVFLWMFGDGTPVQITYFGQANHTYHMPGDYLIKVN
ASNLINFVIFHLTVTTRVLECQEPLVKLALPPQVIMRRSQRNYIEAEIDLHNCFSYQTKH
LWEIYRAASCLHYQEPDKVNLQNVDLSRPQLVIPKLALDIGDYCFVFSVTFGDTPLSRNS
LANVTMMPSKLVPIIDGGSYRVWSKSRDLVLDGNKSYDPNLVESSQTPLKYRWSCTFTKN
SEAIRCPLEFSSEFGFMAIPKSMLQAEVEYTFFLTVSKPGMNSESTNQTVLIKRGTVPIV
SLKCVSCKAQSVYEVSASSYVYLEGRCTNCLDDSWSARWTAQSFDNKTLPLDSSTTSTGD
REMNLVLRLGALKDGQGYTFTLHVIHPSMDEEGFASIDLLPNSPPSGGSCTIAPNGTVHA
LPGKIHFECTGWRDAEDEAGSLVFSLIVRRCKPGHCEEFWVYKGSRSEHSTHLPTGFHES
DFAVDVSVVVQDQQGAAAVALNRSMNVLLPDVSEGFSSLTHWLRNQTESTLHGLLIQGDP
QHVTEFSLALITILNEYESMNYEVEPDLHIVRQNITEALISLKVNTVDDIRKIAAALAQC
TVASKKLECAACQVHTLSKLETMMSILQNETTQGTMTPTTIADNILNIMGDLIHLVNTNP
PRYKHGKLCAGDKSLAVASKAYNLSSDLMRILMKSRVLNEEPLTLQGGEILARGKRSDPL
NLLCYSNQTGCQFFIPHGFNSALPDLTDIIQVMFQVDSNPYPYGFITDYTVSTKVASMEF
HTSNGSQIPVESLDSEKAITVRIDNNSGDRNITAGVATIERRRSVKVDVEANSSNGNARL
HIQVTYVVQDDRYVLSEPEPFITAYLHESGHPNQYNCTDMKQIGMKDLSRQDHKLYTFFL
VPTTGNHSRHYYLNITNHYMWTSVDVTVGLYTSLCQYFDGNENKWSTDGVFPLNDTRPGQ
AVCLTRHLTAFGASLFVPPHSVVFIHPPPPPGINYIVLLTCAVCFVTYSVATIIVHKLDL
LDVNKAGVIPFCGKAGSFKYEVLVKTGWGRGSGTTAHVGISLYGVDYKSGHRHLDGDNTF
HRNSVDIFQIATEKSLGNVWKIRLWHDNKGLSPSWYVQHVIIRDLQSKKEYFFLMNDWLS
VGREESGRRVEREIFAASEMELKRFSRIFVAEVQRGVSEKHVWLSMWDRPPRSRFTRVQR
ATCCALLIFLFLCANAVWYGVVGDKELGDGAVSQHVPLSVDSVAVGMVTSVLVYPVYLFI
LFLFRRARSKTCVRQSLSYFDQQSLEIDNYLDVMESSFISYTGIHGEAFSDQTKTDIPID
DAKSFIQWNSNEGMLSWPDLLSDPSIMGNTIQKLERRRTIRNLGFDVSSHPSEDDSVVLG
LPHSLARQFLASEKDFIMFVSVDGASSMSLPRDLRRISRTETDLLSDLSNPFGDKTETII
LEKLNEKGQAVAGHAKEMTRSPKSTRTGKGFSVGTKHRRRREMLPSWCARVAHALSCFLL
LCCFAVSSWIGVGFTSSVGLMWLISGIFSFLCSFFILEPLKVLFEALYFALAAKRLHPEE
EDTLVECPIVEQVSERITKVRPPQGFALFQAREEAQKVKLLHRMLKNLLVFMLFFLVILI
TNYGEAPKNNSAYLLQRSISQELGTHKFLHIKRSDEFWVWASEMLLPYLHHNQPLQQGYS
SMLGVARLRQIRLKEALPTSCSLQLFSAGRSCPELFDDAIFKSATLPSLNWSYSPPDHTG
AWYWGFLSFYDTSGYVQLLQGSQKDNEELLEELQQSYWIDNLTRALFVEFSLYSPGVELY
ASVTLLLEFPLAGRALPSVNIRAFPLLRLTSGTHLLLVMMVFLMMFVVYFVLSECLIIRK
EGLQYFTRFWNYVQWLLTVLAVCTVVVYLSKASLADRQWDRYLKDKEAFVSLYQVGFLGN
TFHSLSASILFVLTVKAAQQMRFIREWSAFGKTLSLAARELCAASGAVFGLVLVYAQLGF
LVACLCVPEGWHSHTLLIIMDSIYHNRGPLASVANVGPRGLCMSELWLQHLDPVCCGTWQ
LLEVWILLRLFAAVLINSYRQVRLEMFRPAFEPQDYEMVELFLRRLRIWMGVSKVKEFRH
KVRFEGMEPLPSRSSSDSKSIRGLTPSAASDTSSSSSFSTISSQLDSLSAISARERAEID
ANVQRLVPVLDALLSQFDQVNQATEDVYRIECSLEGVQKRASKNRFAKIGKHGRPKTKKS
LSNTQLSSGTSRNITNFAQSKKRKSIRAHNRVHPSVS

>Danio rerio_PKD1a(ENSDARP_39910)
DLSRNRIHSVDWSLFDHLTALKELDLSNNQITTIEERTCDHLFNLTTIDLSFNPFLCDCK
LVRLVSWLQEQGVKVKRPNSMLCDRPPEVRNQPLLNVSVHTCVCEETYAGCLQDEAHTAG
VELVIFSSSTPGPFSREECNSKCFHENQRYGGLGQQRECLCSTNSEPNHISESQCSAACS
DPLVMKECRWTVARDVFQVPKHATTVVVCPPFPIENLRKAVLSVASSVSPASFSWDFGDL
SPRVNTSTPNTTARHKYGVPGRYQAHVSLSAGHQEIMAQGSVSVELPPRLELHCPDLIVA
NQSLEAELSLVNWGGVGVTVDWRISKDGREVARDLCVPSAEPQCPPDALHHVDSSRCFLL
VSEEVSWAEARRNCSGRGGELAVVHSQSLRDLLATKITQNLTELIQYQICQASEEWPVHE
NNFFSPYRCEMWGPGNVCVSLDGGAQPSIHSCTAKRAFICQFTRHVRVPDAGVSMVGTAV
FNTHNPLRSPAVSHTSVPNTPARLLLFAGLSFVSAGRLSSLEFVTHSLDTHTQVRFQVYR
PRCPSFTHTLLPAPDEWMNSTEAPAAPGCPAERHFCPFSERCVSLSSPCPSSACFNCSGV
SPPPAGTQYPEYSLLDEVLISLPAGPAASVLVQEEVQDLLVSPGDIIALQHDAGPSGLLQ
CSPDPSSPWSQSLLIQNRSHWWDANETLQADVEGVWEEGVLCQIRVLYVGQNQTGLQGPF
LRSGLPQVGDYSLEVTSNDEDFPVTASCPIQVIPPLTPTVIHPTNHNNTVYFLPNQTWVL
IKVRSQHSALIGCQGNNLTVAFERACPQSLLSKVAECRQSDPFNDTMFAWVDLQAGSTPG
QTTVVLHVKSEVTEAYLQIQARVQEPLRGLLIQPHPAHRVLMESVVCYTPSVEAGTDPSF
RWTVDDKPHFTYYNSMLNIIYQNAAVYKLTVTAMNQVSMLTEDFNVTVDRMNPMTDPTVH
GVPKIVQQGSLLNLTAFITIDTAVDVTFWWWFGDGGNRTHQFKSPYDDNPSTNMVGIRDH
VEYIYAQPGEYTLLLSTSNRYENKTCKVDVYVFSILTSVQIEVYPPLLRAEKPADFEAHP
LPSPYGIIYTWNFGDNSSIQQGRERRVPHAYTHSGIYNICVNVNNSISSTDTCANIIVYE
DIKGLEVMSSAPTEHNTPTVIRASLEAGNNVTWSFDMGDGKVHKSVEPQIKYKYREDGNY
TVNVTAENAVSSQWLTIPVEVFVLQVLSLEPTGCIEENKIVSFHVFVSGNASGHQYVWSF
GDGSPNETQYGTPLITHSYVNSGDYNLSLLVSSDANKAHFYTRICVQPKVTVVSVTPLRT
HVRLGEESRFTVAAVPEFNYTYLWDFGVVDSGGPVRGGKEMTYTFNSAGEYQVTVTVQNN
ISSINASVSIEIQQSVGLLLISHNGDKGNHLSLHQEYNFKASSDSMNAVYIWDFGDGTQC
NGKIVSHSYNSSGRFSISVIGKNEVSKTKNETSVVVLAPITRLSINASLVNVPLNASVHF
EAQLDQGDDVRYSWILCDRCKSIQGTHTMFYTFLSVGTFNVIVTAENAISMAQSSIFIFV
QRELEGLQIVADDLIEGCCFATNRILHLQASLKEGTNMTFTWNLLREHENHDNLTGKTIE
LNFSTPGPCEVILKATNLLGQLSVNKTIEFLDPVQDLVLESLPNPAAVNAMTNMTVSVNS
GTNLHYKWWADGDLLESDMPSILHRFRSAGLKLVKVEVSNKVNSEVVSKWISIQEPISGL
TFIAKNVTENFVATGDNVSMRGDTQMGTNISWMWLLPDSTKSNQRAISYIFHTPGLFTVA
LNATNDVSGEMYLRDFTVQDRIQGLELKASKQIAAVGENVEFTISVSSGTSVSFILSISG
DATVVLNNLTYVHQFTSVAKYYVNLTAYNHVSSERRTLHIEVMEPVTKLTILDCCDAAIP
VGVPRSYVASTPTREPLTILWTFDLHHGFKISRVGKSMTYAPEQPGNLTIFLRAFNSLNG
LNVTKVIQVQSIIRSALLDAQPSDTFVNKTVNFHVGITPASTPATYQWDFGDGTSGTITT
APFHNHVYLIPGHYVVRVNVSNLVSWVTAQIEVNISVLKCDEPEVQIIQAPRLAIWRHQP
TLVEASVNLKGCVLYGVEYLWEILTSPRCQDDDKKGPPPSKIQLPPEVNVRRLQLSVPKI
SIPAGNYTLVFSLSYEGVPLRKAACLQLSVMSKKLVPIIEGGTYRVWSKTHDLDLSAEQS
YDPNLDPENQVPLSYHWECVSTSKGPDHCSTLHFGLGPSDPVLGISGSELEVDVEYTFRL
TVSKDGMAPESTTQTVCVQSGRIPMVSLKCVSCKAQSRYEISQSSYVYLAGHCSNCQSSH
RGRWTAMTRRNETLVLDLNTTTTGSDSMRLVLRQGILRDRESYIFSLHVTDDGMDREGVA
YIELHPNLPPDGGACSLWADGGGTQVQTLLERVHFNCSGYTDLDETESPLVYSLLVVRCS
ELYCEEFYVYKGTSPEHSAFLPPGFSSAQYRVSVLVMVEDHQGASILARNTSMEVVLPVV
PDGFVSLPHWLSNVTASTLRELLRQGDSQRVRELSLALITVLNEYEQGVSRRRERVSKSE
RQYRVSIRGNITRALTSLDLTTVSDIQQTSAALAQCTAVSREFVCEECQNSTLDKLESML
EILQTDTKQGTVTPTEIADNILNIMGDLIHQVNQVASSPPPEEELQHHPLRVAAKAYTLS
SVLMRILMLGRVLNEEPLILRGAEIAAVGKRADPQSLLCYGESDAPECQGFSIPRPFNSS
LGRAAEGALAPNSDDGIVQLLFQVEPNPFPFNYVDNYPVSTEVASMEFRTVNGTQIPIAD
LDESQAITVAVNNGSATGLDASGLKAVLPPAGAVNISRCDSIIVRVNTRNTNRQAGVYIQ
LNFTVLDGKTHNNTPDSWITAYLDTSEWPNEFNSTDRKRITLNMTRRPDLHHRDYTFFLS
PNVYDTTQDHFINVSSGCGTAEPELLRLEVAVFTSLCQYFSESAKQWRTDGMEPLAETSV
GQAVCRTHHLTAFAASLFVPPDAVSFIIPERSVSRSVVVVLVCVVSLLCYAVAGAVLRKL
DQMDLRRASVVPLCGKDGLYKYEIQLKTGWSPGAGTTAHVGISLHGSEGRSGHRHLDSVG
AFARNSLDIFHIASDSSLGSVLKIRLWHDNKVLDPAWLLQYVLVKDLQTGSSFFFLIEEW
LSVDNEKTDGRVEIEVEASEELYLRDWPRLLRWELQRAVCESHVWLSLWERPSRSPFTRL
QRLTCCSLLLHLQMLAAAVWYGTVSYKHSSSVPVADLVSVNVETLWAGMVSCLLVYPLYL
LVFCLFRLSRSKVVSVEQLPPQVDQESLEIDDFLENSLTGSSFLMLNAIPGEQTYSEETN
IDLPTPSTKSLQRWSMPDCDWPDVLTDPSVEMGPVFPPRLKRGQGSRHLGVDITFSPDHE
DDTVCQNSHRNKYFSSSDEDLIKRILADGQLLSQTDSDITAETNVTGSYGSSIFGDKTEV
ILLQKMNEPVPCATFRRDPPKTAFTSRTVVADVCKPRPLPPLCGLAALWASWAGLILSSS
LSMWLGRGFSEGVALMWLISCIVSFLSSFLLLEPLKVLLEGVYFSLVVRRLRPEEQDVLV
ECPRVERVVQRIPRVRPPQGFALSQAREEARKVRLLHTMLKGFLLYMLFLMVVLLLNYSD
SEKDAHRLRLNAQLQDHFLTKHFNNISSREDVWAWLSNSLLPRLLDEQVLMEKTGSLLIG
RARLRQTRAQLMTLSDPRCPPECPVSGYFPASSWFGCVQAGWAESASGLVQNWSWGQVSV
YSSSGFVQDLSRKMQDSKNLINQLNTHQWLDPLTRALFLEFSLYNINTDLLSVFSFLLEF
PVSERAQLSLDLKTFSLHTLSHGMDLPLFLTLILLVLLIYFSVREGLLVWKQGRCYFLRV
WNLASVCSLLLAVCVASLHLSRSVVSAQQWRAFLQHRDAFTDFFPLAQQNQLLTQMSATL
LFLLVLKASHQLRFLREWGVFGRTLRKSFWELLMVAVTLLVFLLAYSHTGHLVISSTCFK
LIGSSGRGLLSWRPDSGSFPCSGSCFIFYISFTLLRLVLLWILMSALLRNYRRARAELYR
PAVDLQDYEMVELFLRRLKMWMGLSRTKEFRHKVRFEGMELPPSRSSSTSDCKSLCLPPL
DTPEAPPTPDSVDGGSEASWRPTSSSPCSGLGVIVGGQGWKERAEMEATLRRVLPAFDAL
LLQLDRVTHATEDLYRTEYRIERLLRKSRGQERARSRSRRSSSENLPTSVFRHPAHTTTN
PTRKRKHKPPALKNKVHPNTD

>Danio rerio_PKD1b(ENSDARP_127250)
MLFPGLWFSHEGRVLSLEMVTQPSDQMTFARMQILRPYCSPSHHLVPPGCSSLLNPFSCC
SLMAMCNTTGGCSSGQYWCHLLEICLPVTSPCSPYNSFNAGHDFALPPRYPVTPPFFHLM
ADMSLMLPPSSEHTHIRATVQDKHITVYPDDILALQHNRRAGEFLHCVASTSSAWRQSYL
SLPGPEWGGWFEGSFSVQPGKGQWLDGVICDLQVIYEDPMPHYVISPTPNSPMNAESPVT
GLQVLHPKLDKNNQMYVPVNVTTLIVIRIISGEHVTSSWSAPVSKSGVPFVSSCPVEMPE
TEEGGWFSHVYMELSGQEEYILNIKASNSLSAQTLSVRVVSHIPVSGLSIMPEGFRRVLV
DIQQVFTASVTTGSSVTYSWVIDDLVQFAHTGESYSVVFKNPAEYTLKVMAHNPVSSQLM
KVKLIADVMTPLDDLIVISMPEAIAVNTSTRYTIQVKADISIGVTIRWDFGDNTASVSHT
VSPSSEIEELQQRAKHVYLQDSIQHTFASPGDYTLKIKAYNKYDQIEKAETVKVRTPISN
LLVSSSPAVCQVNYTVLFEVSLWPSSFGALYSWNFSDDCEKVKEVYNKVSHVFNKPGTYN
VTIMANNTLSTLTNYTAVEVIEPVSGLQLNYNISIELNSAFKISGKVSSGTHLKWTFEFG
DGTTVINHTGSSASHMYESPGNYTVQVSAYNSVSQEHQLVSIEVYCLIITQITPTDCVLS
QTEIDFEVLVKGFIPALTFEWEFGDGTPLSVVKGATSVTHTFKTAGTYTVGVNAHSLVTS
VYYESSICVEGQITDVSLSSPNSAVAVSEVICFDASVLPKVTEYQFWWHNNFSSDTNPVK
GLSHHCFMFQEEGLCEISVLVYNKVSNGTAKTIILVQRAVSNLCIKYEGNHDAMTVNQSY
HFWAELLGKMASFQWDFGDGSKTEGQNQLHIFGFPGQFHVTVTASNAVSSDSVTVEIEVQ
APLSYVMVNTSRPFVEAGKEILITALTDVRENISFFWTVNPSTPPKIGTSTFTHVFPNAG
VFEIQVAAQNLVSRVEAITHIEVVEKIYGVWIQGQGLRSEKYFLTNQTILLEASVTHGSN
LTYKWTANNSMAGNTKQFPLFTKNSGDIHVRLVVSNALGLVDSELSLRSVELVSGLSIVS
PVKTVTKGKPVNISAILASGTDIKYSWFLDCEHCPVISDVPFILHAFKICGVVKIRVSAS
NVFGSEEATKLLTIEENISKVDFQINGQSRPFFVKSNHLLMLFGSAGPGNVLHWEWVLTL
HNRTVVVLTDNQTVSYSFVDAADHRLSLNASNDISWQTVSYTITVQDAIQGLSLTSSSSV
VCEDDSVTFLTSVSKGSEVSVSLEFVNASYSVDIGRDFTTYSLAVGNHLVRATAKNKVSS
QTATATVRVVERIRDLRLIGCCSAVLEASKNISFQASAFSQANYHWTFLLNGVQSSREIG
QHVHFTPFANGSLSVTVEAENGFCSQSLTSTATIQKHLKKVTLLTSHDGAFIDYPVTFVA
ITDGGSDLKFIWDFGDASEGLLVTDYNKQVHKYNVAGEFLVKVTAFNNISEVSVQIAIEV
QNLVCTQPHIYTVKEEYNVLKSRPSFFEARVDFNGCVTHKASYIWEIFRGPDCPGMNKVN
LNHSVDVTTPLLSLPKHTLKVGNYCLTFTARLKGTPLQQNKTIKLNVVHSRLIPVIKGGS
LRLWSCLCDLTLDATESFDPDSEKNDIDLFKFQWSYTIENTTALSLAISTLHGHISGNSS
MLILPRSVLLPDRVYRFTLTLFKSGRQPASISQSVRVYNATLLTVTVKCVSCNNQLFHMN
HNDHVSLAGYCSSCQDTIQYRWTAENQRGEALTLNEVTTLTGSLRREIVIKPGVLMEGQE
YTFTLNVSDPASGLWGSASITLVSNHPPYGGFCTLSPDDSLYFLETKVSYSCSGWMDDDG
DSAQLIFSLQVAQCEDFGPLCPLITLYRGTQSTLSSLVPLGIKNTVENASVIHVLVHIED
SMGATVVAVKKKLTVLPCDQCTVTWLKKRSQSEFWALIQQGNPQDIMQYSFALTSQLNQL
TSISAQELEDKIHIRTRVIQVLASLPVSSLQDVALISSALAQSTVVPSEVQCSGCYAKVL
QVTKKMIKVIREQTGEGNINPTDTGRNILTVLSNTMTADLRQRSTPDTSEHIRAVSALGQ
VFELMRSLMLSRMRGGTALFLAIPKISAVGIQGDPTEDLRCKDVLTHCQFHIPPALSSQL
KEEKQEVLQILLQMENEENPFIPGAEPPISTMLAAMEFATPQGNPISIANLTLDSAIQVT
LHKQAQEMKDESLLWKNITLKHNGSVNFTVKAMDAEPHTGLYVALNFSLIPGSAEKASGL
VWISINDQPVDLQSGRIHHQELTIFLSAQTPLLQHIIFLTPLLNGSAKELFVKVNSSIGG
VDVTVSVCVFSVLCRFFDVKELRWSSDGLSPLSTSSPHSAHCLTQHLTMFGASLFIHPEA
LLLLPPSEEPVRNVVVGIICGVLLLIHLLVGLMAHKLDHLENLRLCWVPLCGQKGRYQYR
VLVKTGWKRGSGTTAHVGISLYGLNKSGSRHLQRQGAFQRNSMDDFQVETDANLGEIWKI
RIWHDNTGLDPSWYLQHVIVWDIQTENMFFFLVEDWLSVENEKNSGRVEKVILASCPQEL
HQFKRILHSQLLFGLQEHHLWISLWERPTHSRFSRAQRVTCCALLLHLYLAAGAVWYGAV
GRKGSSGRVSTQMVMNAETVLVGMTVAALTFPFQAILKFLFQRTKSKVTLEVSAPPSPVS
HTVEMDVFLSHPDLTCSSFLSLPTCPKSSIYDGPSPFTNSLQSKKLDSEFWNSPDPRNGR
VDQLPSCDSIFGLPELTGTTHLLKRKKALLQLHLSTPTSDHDNGELAKSSASEEDLRTIS
PDMDLTNTLSSDPEASDSGNFTPNDTIPTDTQDSFCSEWSDLSVDTPTYEPGFHRSSSSL
SVLSEASTFLPSLPPDSISTVSTTRIGVVRGVPGFYLPSWVLRMVHLLVAVLLGTCLAVV
GLYGSSFTSSVVLMWLVSTLSAVLTSALLLEPLAICIQALYLATVVRPVDPEVEERLAQE
TEVRRSEEDFRDKVHPLCGYGLLQAKEEARKLRTLRALMRSCLVYMLFLLVVLMVNYQEH
VQMADSRRLHSAIKHTLISASAGKPGLMKLSGWMNAEQWINEKLTSHLYENPSLLLTGPA
RLQKVYFQDFCSQGIRDQFQSGRLSLMPTAHVSSHANPGQQTSTAHSKNTPALSTWQKRA
LCAFSQTEELVLGNNTEYTRQILSDLQKEKWMTTGTKAVLIEFTQYHKQTSILAPVSILL
DQTQTGRILAFISIQPFHISPLSGPDLHVTLTVVLLLFALCFLSTEVRALIRKPSQYLRQ
AWCWFQTLLALLALAAAVLRLYFLYTTTVCISRYRSIPSSFADFHSAATVARKSNQLSAI
LLTLLALKMVGILQFVRRWLVMGRVIWQVFPQICGVVFLLLLLLLLFSHIGMMLFSGSVE
GFRTLGQASSSLLCLLRGRTGLQRLCEHHPVVGPLYCLSAVGIGFWVLGRLCAAVLIRTY
QMVQADIYRPSMEPQDYEMVQFLIKRLKLWMGLSKTKEFRHRVKFEGMRPPPSRSSQVSA
SSNCWTPLSPIGSRQTLLSSASSLASDTSVISDSCDVHPYVERLVPCVDSLLAGFERVNQ
VTEEVYNFELQLQQIQSRISQIRKLPLPVTFTECDLTPKPPLLPRHPSSSVLESKPSPSC
LLNTLPYRRAAHSESSLMGPAVQLGRRILSALDGGRMNSPNPRKRVVPRQRAWNSVTCHS
ADTAQWIAGFHNTDGPLVRPQSQDEDRQRGCEGMPIKRRAWQTEKEL

>Takifugu rubripes_PKD1(ENSTRUP_20126)
MDRLYPSENMASASRGLASAPFCLWRSGAWRRGAPGRRGTAAGAAARVPRTAAACWRRRP
NTPASSTAPTSAWRGPQQPPTSRWLLLCCKISLEIFPRITSPPLISAFWSESWDFVSCDD
LSNNQISTIEEGTCNRQCNLTQIDLSGNPFECHCKLFRLVSWLREKGVKVRRPEATLCDN
PPALRHRPLLNVSLLTCDLNYVACLKESSSGGGAERSELVIFSSSTPGNFTREQCNSVCF
TASHRYGGLGGRHECLCSTNSEPNFISESQCSAACTNPQVMEVIGALPLPIQNVHSSISF
SAASSVAPVTMSWDFGDLSSRVNTSGAGGTTTTSHKYGHPGRYLVSLMGWSGNNKVSAHG
EVVVTLPPKLELHCPTLVVANQSLQLTLVSWGSVDVDVDWKITKHGVQVAKASPHCPKDG
VLHEESSRCFQIVPGELSWTDARKQCLDRGGDLAIVRNDALRNLLARKVTHSMERGVWLG
LSDVNSAGKLHWVNGSEAQEGEEGLAPWSSVARGNLCVSLDQRSQTSSHSCNARRAYVCQ
YNPQVRVPDSGVFAMGLAVFPSHHLLQATAAMITTPPPPHGGVEVLLFPALSFVRAGRLS
SLEFVTRELSSQTHILFQIYRPRCRHPCCCGGPACSPMALCVPSESRSADPPSCPKLEQW
CPFQHRCLPLSSPCQPSSCLNCSQGHQLPSEARMPLYTLQYEVLFSLTAGPAAHVLLQDQ
LEDLLVSRGDVIALQHDAGPASLIHCQSSPHSLWRQPVFALNLSEWFGINNTPVPPDNLA
GDGADPLPDPELDLKALVEGTRGSWLENAVCPIRVLYVGQSETRLRGAELSAGLPQPGLY
NLLVTSAKQSDLVSASCSLQVLPPLDLTVLHPSPQNGTLFLESNRTRLLLRVQSRYETKA
FYRTSNSSATFHPYCPQEFSSRLCHPSTSEGSGAEVAEPSMYAVLDLNLKIKEHTGPVQV
ELMAHNNVTEASLTVLVQLEESLRGLVVQPHPARRVLMESVVSYTASVLEGSNPTFKWTV
DDKPFFTYYNTVLNVIYQHADVYKLTVTAMNHVSTLTEDFNVTVDRLQPMTNLTVKGVPD
VVPQGSTQTLTTSVLIDMAVPATVRWSFGDGGYEQFEHKPPYPSSLTCPESPYQVLLSSN
VTYIYSQPGIYTAVVSVSNRYENISRSINMSVYSILTRVDIQTEPSLLLAGKTADFEAHP
LPSPYGIHYEWNFGDGSALLQGRRVAHTFEKSGPFNVCVSVNNTISSTAVCTEMFAYEEI
ESLTAESSSPTELHSATTVRAHLSSGNNITWTFSMGDGKSYTLSEPTVSHKYAKDGRFTV
NITAMNAVSSGWTIIPVEVFVFQVAGIEPSGCVGEHALVNFRARVSGNASSYLYEWSFGD
GSPNETHHGNPGISHTYRGNGTHPLSLTITSGVSKANFVTQVCVQPVLTKISVTAEKSHF
AVGEKIQFQARAEPEFNYTYEWDFGGEEDLVLPHAPANVVKTYNNPGCYVVTVAASNNVS
NTTGSISIEVLTPVGAVVFQHNGTHYNNLTLGVPYYFSAFSSASNVSYLWNFGHGNLLKG
QNILHTFNTPGHHNITLTAANRVGKNHTTVPVAVLASVSGLTINSSLVNVPLNTSVHFEA
HMDEGDSVRFSWILCDHCTPIFRNNTMFYTFRSVGTFNIIVTAENDVGAAQASIYLFVQR
ELEGLQILVETAEGGGGGVQELDWCYFETNRVVRFHAGFKEGTNLTFTWNVILKNEPDNS
IFNLTGKTAKVNPSKPGPCDIFLQAANLLGQVTVNRTIYFLEPARNVQLQISDNPVAVNA
LINMTVLNMEGSNLQYRWFVNGDDLQWSKSWMSHTFTSAGQKQVTVKVFNEVSSEVRSEI
VSVQEVISGLKITSADATEQNYFPTDVSVCLQGELSTGTNVTWSWLIDGMSKMQKKACVT
FPKPKTVAVTLNATNDVSGKVVSREFFVQERIFSLELKASKKIAAINEKVEFSISLVAGT
NVNLSLSISRDATVVLQPNQTYVHTFSRVDTYMVNLTAYNEVSCKRRNLHIEVMEPVRGL
SIQDSCAAIAVGEKKVFVANVQTGKPVHFLWTFDLHHLHKETHMGKEVSYTAEEEGLLTI
YLGAINALHAQNITRQMLAQNVLMDAVLYALPQDTFVNKMVTMNVLVTPKSNFMDCLWIF
GDVSAPRHTNNTTVGHEYTHPGHYRVQVNCSNLVSWVSAHAEINVSVLECEEPEVQVVQA
PRLAIWRSQPTLVEASVDLKGCLRYGAQYLWQILSAPSCDNDPHFASGRVNGATRSFPVI
PLPAEVDVQRLQLSLPKMVLAAGNYTLVFSLSYENVPLKKAACLQLGVMAARLMPIIEGG
TYRVWSRTQDLQLSAEQSYDPNMDPDNQSLLHYHWECQSTSKGPEHCSTLSFGLGSKGPV
LGISGSELEAGIEYTFKLSIGKEGMPPESTTQTVLVQSGHIPMVYLECVSCKAQSLYEVS
QNSYVYLRGTCSNCQGFHRGRWSAVTLQNDTLVLDSSSTTTGSGGMNLVLRQGVLHLGES
YNFTLHVTDDSLDGEGAASITLHHNMPPDGGECHLRRGGETGQEHGDKEDEVWRIETLLD
RVQFSCSGYSDLGVSETPLLYSLLVNRCRDDYCEEFYVYRGSSPEHSAFLPPGFSSAQHR
VSVFITVEDHQGAAIRALNKTIKVVLPDPPPEYSSLPHWLSDLIDSKLKKLLDQGDFQRV
RELSLVLITVLNEYEQTRESVRVSRVERGYRGRVRNNITRALTALDLTTVNDIQQTSAAL
AQCTAVSREFICEECQNSTLNKLESMLEILQTDTKQGIVTPTEIADNILNIMGDLIHQVS
QSTSQSYNQPPYVDSPSPSFIQKDMGGLDPSPPSLEPHPLRVAAKAYSLSSVLMLILMHA
RVLNEEPLVLKGAEIAATGKLADPQSLLCYHGNNSPGGFTLHETLKANILFLSSRSLRAL
LFSFHQVESNPFPFNYVANYTVSTEVASMEFRTENGTHIPISGLDDSLAITVAVNNGSNG
AETGPEGAGTGGVPTAGAVNISSCDSVIVRVSMGNTNRRAGLFVQLNFTSLQGVGLQDKR
EEAEELSITAYLHSHEKPNEFNCTDRKRITLGMTRGHDLDHRKYTFFLSPELYDTTLDYF
INVSTACGSGSGAAGVRLEVGVFASLCQYFSESEKQWRTDGMVPLAETNASRAVCRTRHL
TAFAAGLFVPANAISFTVPERSGTPSLVVLLVCVLGLMSYVVAAAILHKLDQLDLRRAAV
VPLCGCDGLFKYEIQVKTGWSRGAGTTAHVGISLYGRESRSGHRHLDSRGSFARNALDIF
HIATDTSLGNVWKMRIWHDNKGLSPAWMLQYVLVKDLQTGSSSYFLVEEWLSVDNEKTDG
HVEIEVEASEEAMLLQLPRLLRYELQRALCESHLWLSLFQRPPRSPFTRLQRATCCALLL
QLLLLANTLWYSIVVDVRYSPRPVSRFASLSGETVAVGVVTCLVAYPLYLLIFTLLRMSR
SKCVSVEQVPPQVDQESVEIDDFLDNSMGGTSFLFYNGEVESSPCVCLDRFIFCFRPTRR
KPIVESWDMTEGEMEVRDWPDLLSDAPAMGGVGCGAGLPRLKRGQGSRHLGVDMAFNADN
EDGANQRHKHFTSSDEDLIKHILTDGHRFFSQPDESEMADLSSIFEDQTEVILLQKHHEP
LPLESVRRDPPRTAFTSNTVVTDVCRPRRFPSSCGRAALWGSWTGIALASGVSMWAGRGF
TQNVAMLWLLSCFASFLCSCLLLEPIKVACEAVYYAVYVRRLRPEDQDVLVEFPRVERVV
QRVSKVRPPQGFALSQARQQARKVHMLHTMLKNFLVYTFFLLVVLLLNYSDSDKDAHSLR
LRTQLQRALRTPEYRGVSSVLLWLNQSLFPRLLDDSALLRDTGSVLLGTLRLRQIFDKQT
FHILPADDVVPEVGGDGTAENITDYRNISAVNSVPRAWRSGRLKANDSRDVLQRSLGEAF
SSLQQHHWLDQRTRAVVVEFSLYNINTNLLAVFSFLIEFPVSDRALSSMDLHVITLWPFT
GLDLQLLLTIILLALVLYFLVPGVTGFLREGYTYLLSTWRALGICKLALAASVCGLHLSR
CTMATQLWTQYVKHPHDDFTDFYPLARQTQLYTVASALLLFVFVLKVSHQLRFLREWAVF
GRALRHSVRELLAVAFALLLLLLAYSHAGHLLLHSVIDGYNSVTSTCLSLVGTSGRTLLS
WRASWTTTGPSNTISSLVFHTTFAILRLAFLWLVISVLLRNYQRARAELYRPAVDLQDYE
MVELFLRRLKMWMGLSRAKEFRHKVRFEGMELPPSRSSSTGDCKSLCLPPLDAPESPPTP
DSIDAGSEASWRPASSSPCSLTEAPGVSLGLGLGLGLNLSPGVLMGNINWRERAETEASL
RRLLPTLDALLQQLDRVTVATEDLYHVECRLERAQSKRRHAGSEKGGAAQGSSGDRVETA
GGWRERKRGKEKHGVGKKVEKSELPKDGSASANLKKTPAAASSPFSKPRSAPDSHLPRTN
TPTVPPTTPAPTPPPLLAPNAQNWDPPVERDMPPSSSLFNHPAHTTTIPTRKRKRKTPPL
KNKVHPNLDKHSPGHPKP

>Tetraodon nigroviridis_PKD1(ENSTNIP_7097)
GLTIIHPVPDENNQIHVKINDPTLIVVKVLSGQRVLSSWSTPVLQTGVPFLPSCPEEVVS
SCPGCVARSPDDWFSSVTLALPSVGVQMMNISAMDAVRSQIVTVKVCGYEAATGLSIESH
GCPRMIVDTPQSFTAKVERGSAVKFTWVIDDLEKFTHEGESYTVMFRKPSEHKLKVIASN
PVSSQSEQILLCADDVTPMADPEFLLVRNIVAANVPNLYTIRVKADASLPVTFIWDFGDG
LSNVIHTKPASCQRLMERSESTEKQSYVQDSVNFTYSKADDYEVHVQVSDQYENKNVFIK
IRASLPLNRLVISSSPSMILVEQRLFLEAITDPTSSGVNYAWDFGDGSGIVRNVQQKVSH
AFLSAGFYNITVYANNTLTVLSAWHMVEVSEKISGLTLSHSGPSELKYPTNFMGTVTTGT
SLIWTFEFGDGFLMENLTDSSVSHVYRLPGIYTVRVTVSNSVSQAHQSITTEVYRLAVSG
MLPTKCVESERDTQLTAQVNGNISTLTFHWLFGDGSSVTVVKGQSVVTHTFRTAGNFHIN
LTVFSTVTSASFNTMLCVEVAIRNITILSSQEVGAVGAEVCFQVLVSPDQTTGCQLQWLT
SPSSLLSRAENTQRCLVFGDEESQSIKPVEKFSAAHNIAGATLTVDTAASFWVVSCVGSN
VSVLWDFGDGSPVKHTQNVSHVFTKAGNFTVTATAFNSVSRESVIFCVNIEFPVSDLSIY
IIPPYGVVGEEAVFTAVSSTIGNATYFWIINGKNSSMLRSHQLEFTFLNPGVYQVRVIGT
NSVRREEATISVAVFERIEGLRIECQAIISVKYVPTHENLLFVPSVTKGSNVTYRWLAIQ
SKNHLEITGEGDIFQISAETPGKISVQVTASNFLGEASKSFFLEGVERLKGALITSQSDV
VALGETVNISVSVTAGSHLRYFWHVKPNHPPVETNVSFLLQTFSTVGHSSVNVSVLNVIS
QSNVTKDFTVQEKVQEVDFEIDGGTRPFYVPTKNAVTLHGLSQKGSNLHWSWKIGGATVA
FFNQQTSIYSFLHAGIYQVSLNISNRVSWMAVSHNVTVQDPIKQLVLKVSKSSSCSGEEV
TFVAAISSGSNASFAITFRKGDWVYSQNIPGGRFTTSSLPAGTLLVTVKAWNWVSSAEAS
SSILVIDGIQGLRIVNCCSGSLEAEKASFFKSEIQSRDPVNYTWRFHLVGFEPLWFTGQE
VVFSPPGSGFLLISVLATDGVCSKSVNGTATVQWPVNNLSLVCHSDRIFAGHAARFSADA
FNGTNVSFLWDFGDSTDPLATDSDKVSYTYHTPGKYNIVIIAFNNVSRITAHLYVEVEIL
QCSSPQVSLVHSCSTIIRSRSNYFEASVVSNCSAYNIRYQWEVLTLSATYPEIMLSDNKA
RLGGQEAASLLLLIPKHSLSVGQYCLLFTVSLQGTPLQVQQNTTITVVNAPLVAVIKGGS
KRLWPHLSDLTLDGSESQDLDREQGEEDMLKYDWSFVALSSSQSQLIKQTIESKSSRVTI
PSTHLRPGTVYIFTLTVHKTRRKPSSINQTVIICETPVTPVTVKCVSCSVQSSTHHLVSH
TLPVILRGQCEQCDGQAEYTWTAEDQAGVALDLDDIVSPAENTFSNLELHSGVLQPGHNY
TFTVNVSQPDRGRWGSASVTIRTIALPRGGLCELSPESDIHLLETVVTYNCSGWRQIESR
FSQLIYTFQVELCQGTTCPLLTLYKGTRSTFASLLPVGRLERDRSTSVITATVLIEDHLG
TTVIALKKTLTVKNLMREDAASQWLMNKSQTELRAVVQHGNPQEIIPYAIALTSRLNQEF
ADICPQVDRDIAVMDRREIRKNVTQALTSLPVSSLLDIDQMTSALLQSTAVPSELTCEDC
QKKVLETAGKLIHVLEEQASPGVLSAVKTGGQILNIIGNILAAASKSASSSASDLSPSSI
PQSASSVALSAVDLAGILMRSVMRLRGPQQAPVLLSAPHINTVGFRGDPAHLLCTNHLQS
STSVPCQFYIPPYFTAHLKSQKSEVVQVLLDTDSKLVSNPLATAADPPISTTLVAMELST
PQGKPIAVQHLDPEQAIRVTLPKKGPAGQDSGSTEWKEGKTGNETCLTVSLPTEGSLNFT
IAAVGSKDTYTVFIMLIILSVSGFNASQNSLVRECALSLSDPSKSTVESVFLSPLWEGTG
RPLFVNLTSSMVNSGPVQVSVCVFSSLCQYFNQTEGRWRRDGLQPLEGSTLHEVHCLTNH
LTMFGASLFVHPGAVVLLPPASGPARNMIVAIVCAVLVLIHVVVGILAHRMDYLNSLRLR
QIPLCGPPGLYQYRVLVKTGWRRGSGTTAHVGISLYGVNKSGCHHLHRDGAFQRGSLDQF
LLETDDNLGEIWKIRIWHDNTGLDPSWYVQHVVVWDAQTDHMFFFLLEDWLSVDNHKNST
VEKEVLASCPDELSQFRRVFASQLLFGVFEHHLWVSLWEHPAISCFTRSQRVTCSALVLH
LYLALGALWYGAVGTELQGEPVSAHVPFDLETVAVGMVVAILVFPIQSFLCFLFRKTQSQ
SLPDSSKPTRESYSSLLESKMFDSSILEFWAASGLAPQTDGVCREEGIHTWPSYDSLLNI
PAGEEFTDATRDPKNCKSLPFAGQIRQLRRKKPLTQLRLAPPLSTNIQIPLDQKVSPRRA
NLPKASDHKLATTLTSSVLFLVSGSSLELILTYTEVKKKLMMSLCWLQIDFLYILGVPRG
QPTWLLPSWALRVIYPVVGVSLAACLVVVVLYGSLWPRNVVLLWLISTISAFLTSALLLE
PLKICMQAFICTTIWRPVDPEVEDHLALETTVVTTSGEHSRRVRPPYGYGLLRAKQEARK
ARTLRSHMKHCACQLLFLLLLLMVNYQDRVEQCQARLLHSAIRRALHTAPSGTQNLTALM
DWSDVNQWVNHTLVPHLHQNPLLSLVGLPHLQYTQALSPPESVFLGDTSVTRQLTLAELS
ASDSTKLYVNDLASYLNFITMKKEKIHCCYNLFLFRFKTLSIDFTHYHRESGLFMCVSIQ
LERVALRRLASSLSIHPLLIPSSSGLDLQMALMVVLLLSAFIILFREMRSMSVGRSRYFH
HCKHWSKLIFGLLSMTTAILQFCFQAHARSCISKLQNQGESFIDFHRAACLAQGCSQSGA
ILLTVLILKLLGTLRFVRRWMLLGLVLQRSQRALWAMAALFISLMLVCIHLGIMLFSHSV
EGFSSLHQASISLLSLLRGHTTLQNLCKMHPILSPLFGLLLMFGSVWFLAKLCGAVLIST
YRAEKAELHHPSTEPQDYELVEFFIKRVKLWLGLTKAKEFRHRVKFEGTDISPSRLSQES
HFSTLSSSLSPSRSSSSSSPWRPSTALSVRSDDQSVSDSGLDTQLHLDRLLPCVNALLGR
FDQVNQVTEDIYNLEMKLE

>Gasterosteus aculeatus_PKD1(ENSGACP_25054)
PSGFFCSLLAALCCLGAWGSGPQGDGARSCYPCPVNCSCAPVGPQPSCVVNCSNVGLERA
PAAAEVPQATNVLDLSKNHISSLDTGLLDRLTVLRELDLSNNLITTIDERIYDNLCNLTQ
IDLSGNPFDCDCKLFRLVSWLQEKGVRVRRPEDMLCRQPPELLGQPLLNVSLLTCGLNYA
ACLEDSSSGGGGRSELVIFSSSTPGNFTSEQCNSVCFAALHRYGGLGARRECLCSTNSEP
NFISKARCSAACTNPHVMKVRSTRWSPGVAFRRFMVVHSHGNLVFLMRVSFSAASSVTPV
TLSWDFGDLSSRVNTTESGCTTATHKYGLPGHYAVGLMAWAGHKEVRSARAGVTVTLPPK
LELRCPPLAVANKSLDITLVSWGADGLNVDWKISKDAVTGCECFCPLPACPHFPNNGVCH
DESSRCFQIVSGEFSWTDARQQCSDCGGNLAIVRSDALRILLAPKITQVRGAWLGFSDVD
SPGKLRWMDGSDAQEGEEGPPPRSSIARGNVCVSLDQSAQTSSHPCNAKRAYVCQYNAQV
RVPDAGIYTLGLTVFPSHNPLHRAAPAPLSTPQPPRGGVEVLLFPAMSCVRAGRLSSLEF
VAPELRSQIHVRFQTYRPYCCGGPACAPVAVCVPNDTRSGDPSSCPRLEQWCPFQRRCLP
LLSPCRPSACPNCTQGHLLPPGARRPRYTLQNEVVFTLPPGPAAHVLVREHLEDLLVSPG
DIIALQHDAGPASLLHCKSSPHSMWRQPVFALNQSEWFWINNTAQSIESGVWLEEVVCPV
RVLYVGHSETQLLGVQLSDGLKQPGLYRLLVTSAEPSYPASASCPLRVVPPLGLTILHPH
PENGTLYLQPSNTKLLLRVRSSYPTKAWRPGGNHSVTFQPECPQEFSAGPGLCQPEAGSD
LYAVLDLNLSTEEQRSPVKVELEAHNNVTEASLSVVVHLEEPLRVLVVQPHPAHRVLMES
VVVYTASVQEGSNPTFKWTVDDKPYFTYYNTVLNVIYQQAATYKLTVTAMNHFSKLTEHF
NVTVDRLQPMANVTVKGVPDVVPQCSTQTLTTSVLVDMSVAATFRWSFGDGGYKEFEYKP
PYAPSLLCPDSPNQVLLSNNVTYIYSQPGIYTALVSVSNRYENISQSINMSVYSILTRVD
IQTEPLLLLTGKSADFEAHPLPSPYGIHYDWHFGDGSALLRGRRVAHTFAQSGVFNVCVH
VNNTISSMDACAEMFVYEEVGDLTAESSSPTELHSPTTVRARLGLGNNITWRFSMGDGTV
YTQPEPEVSHSYIKDGNYTVNVTAANAVSSGWTILPVQVFVFQVVKMEPNGCVQEQTPVN
FQAWVSGNASAHLYEWSFGDATANETHRGDPRVSHTYWTSGNYHLSLLLSSGVNEATKAN
FFNWVCVQPALTNISLNLEKSHYAVGDEIRLQARAQPEFNYSYQWDFGRGEDVGLVSGSG
NVRTTYKNPGRYSVTVIAFNNISTINTSVLIEVFMPVGPIVIQHNGTKYNNLTLKAPYSF
TTSSMAYNVTYVWSFGDENKLTGQSVLHNFNTSGNYNITLTAANTVSRNHTTLPVTVLTP
ICGLTVNASLVNVPLNASVHFEAQMEEGDDVRFSWNLCDRCTPIQEKHTMFYTFRSVGTF
NIIVTAENDVGTTQASVFLYVQRELEGLQILAEDEIRGAGLDGCCFATNRVLHLHAGLKE
GTNMTFTWSLIKEPDSQSSSFNVSGKTVQVNFSTPGPCDIFLRAANLLGHLSVTRTIRFL
EPAGGVNLLVSDNPVAVNASTNLTVLSLEGSDLQYRWSVNGDPLKWNHPWKTHTFMSPGL
KLVTVEVFNEVSSKVESKIVSVQEVISGLRFNATNVTKQGYVATGDSVSLQGEVLTGTNV
TWTWQFKGRTEMGRNTSIVFQEAKTATVTVNATNDINGQVVSREFFVQDKIKGLELRASK
KFAAVGEKVNLTVLMAAGSDVSLILNISGDTTVTLQPNQTYSHTFTRVATHMVNLTAQNQ
VSLIKWHLQVEVMEPVQGLSIQGSSDAIPVGVRRLFAANILTGKPVRFLWTFDLHHHAMT
MHMTKEVFYTPEEPGLLTIYLKALNTLHSQNVTKYIMVQNQLSAAVLHAAPVDTFINKTV
TLIAHITPRSNSVTCLWDFGDSSTPLHTNTTTVGYEYSHPGQYSVQVNCSNLVSWVLAQV
EISISVLECEEPEVQVVQAPRLAIWRSQPTLVEASVDLKGCLHYGAQYLWQILATPSCDN
DEGPSVAPGVDVRRLQLSLPKMALAAGNYSLVFSMSYEGVPLRKAACLQLSVMATRLMPI
IEGGTYRVWSRTQDLKLSAVQSYDPNMDPDRQSLLHYHWECQGTSKGAEHCSSLNFGLGT
SDPVLGISGSELEAGVEYTFRLTISKDGMPPGSTTQTVLVESGHIPMVSLECVSCKAQSF
YEVSQNSYVYLKGTCENCHGFRRGRWSAMTLENQTLVLDSSSTTTESDGMDLVLRQGVLL
NGESYNFTLHVTDESLDGDGAASITLHSNMPPAGGECHLRGGGEAGMEYGKDGEGWRIRT
LLDRVHFNCSGKRGGNGGQTPLLYSLLVTRCRDDYCEEFCVYKGSSPEHSAFLPPGFSSV
QNRVAVSIRVEDHQGAAITALNKSIEVVLPEAPREYKSLPHWLSELTDSKLKKLLEQGDS
QRVRELSLALITVLNEYELTRHSQNERGYRVRIRSNITRALTALDLITVNDIQQTSAALA
QCTAMSREFICEECQNSTLNKLESMLEILQTDTKQGTVTPTEIADNILNIMGTRPSAVSG
DQQGALPLEPPPPSRVAAKAYSLSSVLMRILMHARVLNEEPLVLRGAEIAATGKLADPQS
LLCYHDHNSPECKRFSIPRAFNYSLGRAAAGNSIMQLLFQVESNPFPFNFVANYTVSTEV
ASMEFRTENGTQIPISGLDDSLAITVAVNNGSGGGEVDLVGSGTRGIPTAEANISHCDSV
IVRVSTGNTNREAGMFVQLNFTNNLQDNAEEPYITAYLHSHEGPNEFNCTDKKRITLGMT
RGQDLDHRKYTFFLSPELYDTTLDYFINVSTPCSPSSPPAGVRLEVGVFASLCQYFSESG
KQWRTDGMVPLAETNASRAVCRTRHLTAFAAGLFVPADAISFKVPERSGAPSLVVLLVCV
LGLLSYVVAAALLHKLDQLDLRRAGVVPLCGQDGLFKYEVQIKTGWSRGAGTTAHVGVSL
YGREGRSGHRHLDSRGAFARNALDIFHVATDTSLGNIWKIRIWHDNKGLSPAWLLQYVLV
KDLQTGSSSYFLVDEWLSVDNERTGGQVEVEVEATEEAVLRQLPRRLQRELQRALCDGHL
WLSLWERPPRSPFTRLQRATCCALVLQLFVLANALWYSIVVDGRPSARAASRFSSLSGET
VAAGVVTCLVVYPLYLFVFTLFRMSRSKCVSVEQVPQQVDQESVEIDDFLDDSIDGSSFL
FFNGEVESHGTIKNDKEKGKGSCNLSWGMAEDEMEDGDWPELLSDVSVVGGAGHGAGLPR
LKRGQGSRHLGVDMTFNPDDVEGTDQRDKYFTSSDEDLIKHILADGQNFFPQTDESEMAD
LLSILGDKTEVILRQQLNEPLPLDTVRRDPPKKAFISNTVVTDVCRPRRFPPWCGRAALW
GSWAAIAVANGVSIWAGHGFSQSVAMMWLVSCFASFLCSCLLLEPAKVLCEAVYYAVCVL
RLRPEDQDVLVEFPRLERVVQRVARVSPPQGFALSQARHQARKVTMLHTMLKNFLVYMFF
LLVVLLLNYSDSAKDTHSLRLRTQLQRALHTPVYHNVSSRADALMWLNESLLPQLLDDSA
LLRNTGSVLLGTLRLRQIRDTQGEMKSLYLCCELVWIQVVIQCVLKSHKSLLVVSYFTYF
FWGGGQLCHSGDVIQQLNRSLDEASSSLQQLQELHWLDYRTRAVFVEFSLYNINTNLLAV
FSFLVEFPVSERAQSSLDLLVITLWPITGLDLQLLLMIILVGLVLYFLLRGILGFLREGY
AYLLSTWRLLGICKLVLAASVCGLHLSRCAAATQQWASYLRHPRDAFTDFYPVARQSQMY
TAASALLLFVLVLKASHQLRFLREWAVFGRALRCSAWELLGVALALLLLVLAYSHTGHLL
LHSVYDGYGSVSAACRSLLGAGGRGLMTWRPSWTVAGPSSPAFALVFHASFAVLRLLLLW
FVICVLLRNYRRARAELYRPAVDLQDYEMVELFLRRLKMWMGLSRAKEFRHKVRFEGMEL
PPSRSSSTSDCKSLCLPPLDGPDSSPTPDSVDAGSEASTSWRERTETEASLRRLLPTLEA
LLQQLDRVTMATEDLYHIERRME

>Oryzias latipes_PKD1(ENSORLP_24551)
CLFVSAEICQKTTSPPLIVACWTACRAFESCKDLSNNQITTIEERICDNLCNLTEIDLSG
NPFECNCKLFRLLRWLQVKGVQVRHPNSMLCHQPPELHSKPLLNVSRITCGPSYAACLED
SSNGGGRSELVIFTSLNAGNFTRQQCNSVCFALYHRYGGLGEHSECLCSTNIEPNLISES
ECSPDCTDPRVMTVTAPPQQSVHQQIQLSAASSVTPITLSWDFGDGSLPLTTAGDGAGSA
VHKYGLPGRYIVEVRASAVQKMALTQQEVNLTLPPKLELHCPPLVVANQSLEVTLVSWGG
VDLDVNWTIAKEGVEVAKARCPNDGVYHAESSSCFQIFTAELNWTDARLQCLNRGGDLAK
VRGEALRSLLAHNVTHFMERGVWLGLSDMDSPGKLHWVNGSEVEENSPSRPDISPGNACV
SLDQDSQISSHLCSSKRVYMCQYTLPVRVQDGGVFILGMPVFPTHSPLHLASAILSSAPQ
PPKSAIEMLLFPALSFLQEGRLSSLEFVTQELSSQVQVRLQIFRPHCPHQKQHLLLPGCG
GLVCAPVAVCVPDDRSNDDPPSCPRLEQWCPFLSSCQPLSSPCHPSSCQNCTHAHYLPPG
MWRPLYILQNEVELRLPIGPSAHILIQDQLEDLLVSGGDVIALQHDGGPSSLLQCQSSAQ
SPWGQPILALNMSKWFWTNNTRQSADSSTNPLPDPELDLEALLQDGVGGWLEEAVCSIRI
LYVGHSKTQLHGVQLSAGLPQPGLYSLLVSSTGASYPASASCLLQVLPPLALTVLHPPSQ
NGSIFLQPSSTRLLLRVQSRYATTASRRGSNHSVRFQSECPSEFAFTTLCQPVSSSESGL
PGSDPSLFAVLDLNLAAEEQKGSVQVELLAHSEVTEASLVVLIQLEVPLQGLQVEPPPVH
RVLMESVVSYTASVTEGSNPTFKWTVDDKPYFTYYNSVLNVIYQHAATYKLTVTASNHVS
TLTEHFNVTVDRLQPMADLTVSGVPDVVPQGSNQTLTTSVLVDMTVAATFRWSYGDGGYE
EFEFEPPYPPSLLCPDSPNQVLLSKNITYIYSQPGIYTAQVSVSNRYENISQTINMSVYS
ILTRVDLQTEPQLLLVGKSADFEAHPLPSPYGIHYTWHFGDGSALQTGRRVAHTFKKSGP
FRVCVSVNNTISSNEACAKMFVYEEIEDLTAQSSSPTELNTFTEVSARLGSGNNITWSFS
MGDGSIYTMSESHMRHKYMKEGNYTVNVTAINAVSSGWTILQVHVFVFQVIRMEPSGCVQ
ERTAVNFQAWISGNASVHLHQWSFGDGSLNETHQGLPRVSHTYQRSGTYHLSLLLSSGVN
QATKANFFNWVCVQPVLTKISFNPEKSYYAVGEEIVFQAKAEPEFNYSYKWDFGKGEDLV
AHGSSKAVTVYKEIGSYIVTVYIFNNISASNSSSVIKVFMPIGPIFVQHNGTKSNNLTLG
DVYSFRTSSLATNVTYTWNFGDGQILTGQNVLHVYNTSGNFNITLKANNIVSENDTILPV
AVLAPVRGLTINASSVNVPLNASVDFEAHVEQGDRLRYSWILCDHCTSIPGASTMFYTFR
SVGTFNIIVTAENDVASEQASIVLFVQRELEGLQIIREEIKEGSDWNRWCYATNRVLHLQ
AGLKEGTNMTFLWQITKEQNSWNESGKTVELNFSYPGPCDVVLWAANRLGQLSTNRTIHF
IEPAGGVSLHINTNPVAVGALTNLTALVKQGSELQYRWSKEDCDLQWTKPSLTLSFNRPG
YEQVTVEVFNEVSSEVVSVVVHVRDLISGLNFTATNVTEQGFAMTGVSVSLQGKVEKGTS
VEWTWLLDGKVMTTGWQTSVTFHEPKSVIITLSAANIISRQVVSREFIVQDKIQGLALKA
SKKLAAINERVEFNISMTSGTDVQLIFSVGGEAKVIPFTYTHVFTRVETYMVNITALNKV
SSDWLKFQVEVMEPVNGLAIEGLCKAIPVGVKKWFVASVIKGKPVSFIWNFDLNHHKASR
WGKEAHYTPEEPGSLTIHLRGFNNLKGQNITKHIQVQHLLRTASLHAEPRHTFINKTVNL
SASVTPKSSQMKCSWDFGDGSTPAYTDGTSVVYVYREQGHYLVQVNCSNLVSWVLAHVEV
NITVLECEEPEVQIAQTRLVIWRSQPIVVEANVDLKGCIRYGPQYLWQLFQTSSCKGGVM
KGEPLTPGSSREVYLPAEVDVQQLQLSLPKMTLMAGNYSLVFSLSYEGVPLKKAACLQLS
VKAAKLKPIIEGGTYRVWSRTQDLQLSAEQSYDPNMDPDSQSLLHYHWECQSTSKGPEHC
STLNFGLGSSGPVLGISGSELEAGVEYTFKLTISKDGVAPESSTQTVLVQNGDIPTVYLE
CVSCKAQSIYEVSQNSYVYLKGICSNCGGFHHGRWSAVTLHNETLVLDSSSTTTGSDGMN
LVLRQGVLRDGDSYVFTLHVTDSSLDGEGAASIMLHYNLPPEGGECHLRGGGESGVLYGD
GTTDGWRIRTLQDRVHFNCSGYRDLGVSETPFLYSLLVTRCREEYCEDFCVYKGSNQEHS
AFLPPGFSSAQHRVAVSITVEDHQGAANTALNKTIEVWLPEPPPEYTSLPHWLSELTDSQ
LKKLLEQGDSQKVRELSLALITVLNEYEQSRESTRVSREEHGYRVRVRSNITRALTSLDL
STVSDIQQTSAALAQCTAVSREFICEECQNITLNKLESMLEILQTDTKQGVVTPTEIGDN
ILNIMGDLIHQVSQSASQSTFHSVYVDSPPPSSAFSTDEELVNMLDSSPAFLEPHPLHVA
AKAFSLSSVLMLILMHARVLNEEPLILRGAEIAATGKLADLQSLLCYHGNNSPGWFITHK
TISAHASFKHSGNIQNRLFSFLPQVDSNPFPFNYVPNYAVSTEVASMEFRTENGTQIPIS
GLDDSLAITVAINNSSSTESGADGSHSGGVPAAANISHCDSVVVRVSSGNTNRRAGLFVQ
LNFTCLPDPEDEDGRRMLREEPYINAYLHTHERPNRFNCTESKRITLSMTRGSDHRKYTF
FLSPESYDTTLDYFINVSTPCHPDSAPAGVHLEVGVFTALCQYFSESEQQWRTDGMVPLA
ETNSSRAVCRTRHLTSFAAGLFVSSNAVSFRAPESPGGGSLFVLLPCLLGLLSYVVAAAI
LRKLDQLELRRAAVVPFCGQDGLFKYEIQVKTGWGPGAGTTAHVGISLYGRGGRSGHRHL
DSKGAFARNALDIFHIATDSSLGNVWKIRVWHDNKGLSPAWMLQYVLVKDLQTGSSFFFL
VEEWLSVDNERTGGRVEMEVEASEEAVLRQLPRLLRCELQRALCESHLWLSLWARPPRSP
FTRLQRATNALWYGAVLDLRFSRAVSRLSPLDGATVGVVTCLVVYPLYLLVMGVFRMSRS
ECVTVEHVPPQGDQESVEIDDFLDNSMAGSSFLFFNGEVD

>Homo sapiens_PKD2(ENSP_237596)
MVNSSRVQPQQPGDAKRPPAPRAPDPGRLMAGCAAVGASLAAPGGLCEQRGLEIEMQRIR
QAAARDPPAGAAASPSPPLSSCSRQAWSRDNPGFEAEEEEEEVEGEEGGMVVEMDVEWRP
GSRRSAASSAVSSVGARSRGLGGYHGAGHPSGRRRRREDQGPPCPSPVGGGDPLHRHLPL
EGQPPRVAWAERLVRGLRGLWGTRLMEESSTNREKYLKSVLRELVTYLLFLIVLCILTYG
MMSSNVYYYTRMMSQLFLDTPVSKTEKTNFKTLSSMEDFWKFTEGSLLDGLYWKMQPSNQ
TEADNRSFIFYENLLLGVPRIRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGP
RNGTAWIYTSEKDLNGSSHWGIIATYSGAGYYLDLSRTREETAAQVASLKKNVWLDRGTR
ATFIDFSVYNANINLFCVVRLLVEFPATGGVIPSWQFQPLKLIRYVTTFDFFLAACEIIF
CFFIFYYVVEEILEIRIHKLHYFRSFWNCLDVVIVVLSVVAIGINIYRTSNVEVLLQFLE
DQNTFPNFEHLAYWQIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGF
AIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPIY
FTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAEMELSDLIRKGYHKALVKLKLKKN
TVDDISESLRQGGGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRD
DLEKEREDLDLDHSSLPRPMSSRSFPRSLDDSEEDDDEDSGHSSRRRGSISSGVSYEEFQ
VLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGVAEDERLGRDSEI
HREQMERLVREELERWESDDAASQISHGLGTPVGLNGQPRPRSSRPSSSQSTEGMEGAGG
NGSSNVHV

>Pan troglodytes_PKD2(ENSPTRP_27941)
MVNSSRVQPQQPGDAKRPPAPRAPDPGRLMAGCAAVGASLAAPGGLLWGTRLMEESSTNR
EKYLKSVLRELVTYLLFLIVLCILTYGMMSSNVYYYTRMMSQLFLDTPVSKTEKTNFKTL
SSMEDFWKFTEGSLLDGLYWKMQPSNQTEADNRSFIFYENLLLGVPRIRQLRVRNGSCSI
PQDLRDEIKECYDVYSVSSEDRAPFGPRNGTAWIYTSEKDLNGSSHWGIIATYSGAGYYL
DLSRTREETAAQVASLKKNVWLDRGTRATFIDFSVYNANINLFCVVRLLVEFPATGGVIP
SWQFQPLKLIRYVTTFDFFLAACEIIFCFFIFYYVVEEILEIRIHKLHYFRSFWNCLDVV
IIVLSVVAIGINIYRTSNVEVLLQFLEDQNTFPNFEHLAYWQIQFNNIAAVTVFFVWIKL
FKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECI
FTQFRIILGDINFAEIEEANRVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQ
QKAEMELSDLIRKGYHKALVKLKLKKNTVDDISESLRQGGGKLNFDELRQDLKGKGHTDA
EIEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDLDLDHSSLPRPMSSRSFPRSLDDSE
EDDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERA
KLKRREVLGRLLDGVAEDERLGRDSEIHREQMERLVREELERWESDDAASQISHGLGTPV
GLNGQPRPRSSRPSSSQSTEGMEGAGGNGSSNVHV

>Gorilla gorilla_PKD2(ENSGGOP_3268)
MVNSSRVQPQQPGDAKRPPAPRAPDPGRLMAGCAAVGASLASPGGLREQRGLEIEMQRIR
QAAARDPPAGAAASPSPPLSSCSRQAWSRDNPGFEAEEEEEEVEGEEGGMVVEMDVEWRP
GSRRSAASSAVSSVGARSRGLGGYHGAGHPSGRRRRREDQGPPCPSPVGGGDPLHRHLPL
EGQPPRVAWAERLVRGLRGLWGTRLMEESSTNREKYLKSVLRELVTYLLFLIVLCILTYG
MMSSNVYYYTQMMSQLFLDTPVSKTEKTNFKTLSSMEDFWKFTEGSLLDGLYWKMQPSNQ
TEADNRSFIFYENLLLGVPRIRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGP
RNGTAWIYTSEKDLNGSSHWGIIATYSGAGYYLDLSRTREETAAQVASLKKNVWLDRGTR
ATFIDFSVYNANINLFCVVRLLVEFPATGGVIPSWQFQPLKLIRYVTTFDFFLAACEIIF
CFFILYYVVEEILEIRIHKLHYFRSFWNCLDVVIVVLSVVAIGINIYRTSNVEVLLQFLE
DQNTFPNFEHLAYWQIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGF
AIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPIY
FTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAEMELSDLIRKGYHKALVKLKLKKN
TVDDISESLRQGGGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRD
DLEKEREDLDLDHSSLPRPMSSRSFPRSLDDSEEDDDEDSGHSSRRRGSISSGVSYEEFQ
VLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGVAEDERLGRDSEI
HREQMERLVREELERWESDDAASQISHGLGTPVGLNGQPRPRSSRPSSSQSTEGMEGAGG
NGSSNVHV

>Callithrix jacchus_PKD2(ENSCJAP_11724)
MVNSRRVQPQQPGDAKQSPAPRAPGPGRLMAGGAAVGASLAARGGLREQRGLEIEMQRIR
QAAARDPPAGASASPSPPLSSCSRQAWSRDNPGFEAEEEEEEEEEEEVEGEEGGMVVEMD
VEWRPGSRRSAASSAVSSAGARSRGLGGYHGAGHPSGRRHRREDQGPPCPSPTGGGDPLH
RHLPLDGQPPRVAWAVRLVRGLRGLWGTRLMEESSTNREKYLKSVLRELVTYLLFLIVLC
ILTYGMMSSNVYYYTRMMSQLFLDTPVSKTEKTNFKTLSSMEDFWKFTEGSLLDGLYWKM
QPSNQTEADNRSFIFYENLLLGVPRIRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDR
APFGPRNGTAWIYTSEKDLNGSSHWGIIATYSGAGYYLDLSRTREETAAQVASLKKNVWL
DRGTRATFIDFSVYNANINLFCVVRLLVEFPATGGVIPSWQFQPLKLIRYVTTFDFFLAA
CEIIFCFFILYYLVEEILEIRIHKLHYFRSFWNCLDVLIIVLSVVAIGINIYRTSNVDVL
LQFLEDQNTFPNFEHLAYWQIQFNNVAAVIVFFVWIKLFKFINFNRTMSQLSTTMSRCAK
DLFGFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRV
LGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAEMELSDLIRKGYHKALVKL
KLKKNTADDISESLRQGGGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEH
QQMRDDLEKEREDLDLDHSSLPRPMSSRSFPRSLDDSEEDDDEDSGHSSRRRGSISSGVS
YEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGVAEDERLG
RDGEIHREQMERLVREELERWESDDAASQISHGLGTPVGLNGQPCPRSSRPSSSQSTEGM
EGAGGNGNSNVHI

>Mus musculus_PKD2(ENSMUSP_84041)
MVNSRRVQPQPPGDAGRSPAPRASGPGRLVAGGAGLAVPGGLGEQRGLEIEMERIRQAAA
RDPPAGASASPSPPLSSCSRQAWSRDNPGFEAEEDDDDDEVEGEEGGMVVEMDVEWRPGS
RRSASSSAVSSVGARGRGLGSYRGAAHLSGRRRRLEDQGAQCPSPAGGGDPLHRHLPLEG
QPPRVAWAERLVRGLRGLWGTRLMEESNANREKYLKSVLRELVTYLFFLVVLCILTYGMM
SSNVYYYTRTLSQLFIDTPVSKTEKTNFKTLSSMEDFWKFTEGSFLDGLYWKAQTSNHTQ
ADNRSFIFYENLLLGVPRLRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGPRN
GTAWMYTSEKELNGSSHWGIIASYSGAGYYLDLSRTREETAAQLAGLRRNFWLDRGTRAA
FIDFSVYNANINLFCVVRLLAEFPATGGVVPSWQFQPVKLIRYVTAFDFFLAACEIIFCF
FIIYYVVEEILEIRIHRLSYFRSFWNCLDVVIVVLSVVAMVINIYRMSNAEGLLQFLEDQ
NSFPNFEHVAYWQIQFNNISAVMVFLVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFTI
MFSIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPLYFT
TFVFFMFFILLNMFLAIINDSYSEVKSDLAQQKAEMELSDLIRKGCQKALVKLKLKRNTV
DAISESLRQGGGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEREHQQMRDDL
EKEREDLDLEHSSLPRPMSSRSFPRSLDDSEEEDDEDSGHSSRRRGSISSGVSYEEFQVL
VRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGVAEDARLGRDSEIHR
EQMERLVREELERWESDDAASQTGHGVSTQVGLGGQPHPRNPRPPSSQSAEGLEGGGGNG
SANVHA

>Rattus norvegicus_PKD2(ENSRNOP_2916)
MVNSSRVQPQPPGDPGRSPAPRASGPGRLLAGGAGLAVPGGLREQRGLEIEMERIRQAAA
RDPPAGASASPSPPLSSCSRQAWSRDNPGFEAEEDDDDDEVEGEEGGMVVEMDVEWRPGS
RRPASSSAVSSAGARGRGLGSYRGAAYPSGRRRRLEDQGAPCPSPAGGGDPLHRHLPLDG
QPPRVAWAERLVRGLRGLWGTRLMEESNANREKYLRSVLRELVTYLFFLILLCILTYGMM
SSNVYYYTRTLSQLFIDTPVSKTEKTNFKTLSSMEDFWKFTEGSFLDGLYWKAQSSNHTQ
ADNRSFIFYENLLLGVPRLRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGPRN
GTAWIYTSEKDLNGSSHWGIIATYSGAGYYLDLSRTREETAAQLAGLRRNFWLDRGTRAA
FIDFSVYNANINLFCVVRLLVEFPATGGVVPSWQFQPVKLIRYVTAFDFFLAACEIIFCF
FILYYVVEEILEIRIHRLNYFRSFWNCLDVVIVVLSVVAMMINIYRMSNAEGLLQFLEDQ
NSFPNFEHVAYWQIQFNNIAAVMVFLVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFTI
MFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPLYFT
TFVFFMFFILLNMFLAIINDSYSEVKSDLAQQKAEMELSDLIRKGCQKALVKLKLKRNTV
DAISESLRQGGGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEREHQQMRDDL
EREREDLDLEHSSLPRPMSSRSFPRSLDDSEEEDDEDSGHSSRRRGSISSGVSYEEFQVL
VRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKVKRREVLGRLLDGVAEDARLGRDSEIHR
EQMERLVREELERWESDDAASQSGHGLGTQVGLGGQSHPRSSRPPSSQSAEGLEGGGGNG
STNAHA

>Canis familiaris_PKD2(ENSCAFP_14105)
MVVEMDVEWRPGSRRSAASSAGSSGGGRARGLGGFRGSGPPSGRRRRREDPGPPSPSPAG
GGDPRHRHLPLALDGQPPRVAWAERLVRGLRGLWGTRLMEESNTSREKYLKSVLREMATY
LLFLIVLCILTYGMMSSSVYYYTRIMSQLFLDTPVSKTEKTNFKTLSSMEDFWKFTEGAL
LDGLYWKTQPGNRTEADNRSFIYYENLLLGVPRIRQLKVRNGSCSIPQDLRDEIKECYDV
YSVSSEDRAPFGLRNGTAWIYTSEKDLNGSSHWGMIATYSGAGYYLDLSRTREETAAQVA
SLKKNVWLDRGTRATFIDFSVYNANINLFCVIRLLVEFPATGGVIPSWQFQPVKLIRYVT
TFDFFLAACEIIFCFFILYYVVEEILEIRIHKLHYFRSFWNCLDVVIIVLSVVAIGINIY
RTSNVEVLLQFLEDQNTFPNFEHLAYWQIQFNNIAAVIVFFVWIKLFKFINFNRTMSQLS
TTMSRCAKDLFGFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFA
EIEEANRVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAEMELSDLIRKG
YHKALVKLKLKKNTVDDISESLRQGGGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGD
QELTEHEHQQMRDDLEKEREDLDLDHSSLPRPLSSRSFPRSLDDSEEDDDEDSGHSSRRR
GSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDG
VAEDERLGRDSEIHREQMERLVREELERWESDDAASQISHGLGTPMGLNGQPRPRSSRPS
SSQSTEGMEGAGANGSSNIHV

>Felis catus_PKD2(ENSFCAP_2613)
GGRQNQGQAAAKGQGXRGRGLGGYHGTGHPSGRRRRREDQGPPSPSPAGGGDPLHRHLPL
DGQPPRVAWAERLVRGLRGLWGTRLMEESNTNREKYLKSVLRELATYLLFLIVLCILTYG
MMSSSVYYYTRIMSQLFLDTPVSKTEKTNFKTLSSMEDFWKFTEGALLDGLYWKTQPSNN
TDADNRSFIYYENLLLGVPRIRQLKVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGP
RNGTAWIYTSEEDLNGSSHWGMIATYSGAGYYLDLSRTREETAAQVASLKNNVWLDRGTR
ATFIDFSVYNANINLFCVIRLLVEFPATGGVIPSWQFQPVKLIRYVTTFDFFLAACEIIF
CFFIFYYVVEEILEIRIHKLHYFRSFWNCLDVVIVVLSVVAIGINIYRTSNVEMLLQFLE
DQNTFPNFEHLAYWQIQFNNIAAVIVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGF
AIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPIY
FTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAEMELSDLIRKGYHKALVKLKLKKN
TVDDISESLRQGGGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRD
DLEKEREDLDLDHSSLPRPMSSRSFPRSLDDSEEDDDEDSGHSSRRRGSISSGVSYEEFQ
VLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGVAEDERLGRDSEI
HREQMERLVREELERWESDDAASQISHGLGTPVGLNGQPRPRSSRPSSSQSADGIEGAGA
NGSSNLQV

>Bos taurus_PKD2(ENSBTAP_26682)
MVNSSRVQPQQPGDARRSPAPRAPGPGRLMAGGAIAGAGLAAPGGLREQRGLEIEMERIR
QAAARDPPAGASASPSPPLSSCSRQAWSRDNPGFEAEEEEEEEEVEGEEGGMVVEMDVEW
RPGSRRSASSSAVSSAGARGRGLGGYHGAGHPSGRRRQREDQGPPSPSPAGGGDPLHRHL
PLDGQHPRVAWAERLVRGLRGLWGTRLMEESSTDREKYLKSVLRELATYLLFLIVLCILT
YGMMSSSVYYYTRIMSQLFLDTPVSKMEKTNFKTLSSMEDFWKFTEGALLDGLYWKTQPS
NRTEADNRSFIYYENLLLGVPRIRQLRVRNGSCSIPLDLRDEIKECYDVYSVSSEDRAPF
GPRNGTAWIYTSEKDLNGSSHWGMIATYSGAGYYLDLSRTREETAAQVANLKKNVWLDRG
TRAIFIDFTVYNANINLFCVIRLLIEFPATGGVIPSWQFQPVKLIRYVTTFDFFLAACEI
IFCLFILYYVVEEILEIRIHKLHYFRSFWNCLDVVIIVLSVVAIGINIYRTSNVEALLQF
LEDQNTFPNFENLAYWQTQFNNIAAVIVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLF
GFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGP
IYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAEMELSDLIRKGYHKALIKLKLK
KNTVDDISESLRQGGGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQM
RDDLEKEREDLDLDHSSLPRPMSSRSFPRSLDDSEEEDDDDSGHSSRRRGSISSGVSYEE
FQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGVAEDERLGRDN
EIHREQMERLVREELERWESDDAASQISHGLGTPLGLNGQPRPRSSRPSSSQSTEGMEGG
GGNGSANIHV

>Monodelphis domestica_PKD2(ENSMODP_25924)
MVNPSRVKPQLEAGAPRRAQPPRPGEPAAARARLSVPAASADGCGGLAAPGLPSPGGLRE
QRGLEIEMERIRQAAARDPPAGASASPSPPLSACSRQAWSRDNPGFEPEDEDEEDDDEEV
EGEEGGMVVEMDVECRPGSRRSAASSAVTSSCASGLGLGSFHGANIPSGRRRRRETQGAL
GCSSPAGPGEALHRHLPLDGPHQPQPPPPPLPPPRVPGAKRLLRALRGLWGTRLMEESST
SREKYLKSVLRELVTYFLFLVVLCILTYGMVSSSMYYYTRVMSQLFLETPVSKMEKTNFK
TLSTMEDFWKFTEGSLLDGLYWEMWYSNRTGAENRSFIYYENLLLGVPRIRQLKVRNGSC
SIPPDLREEIKECYDVYSISNEERAPFGLRHGTAWTYTNEKDLNGSSHWGLIATYSGAGY
YLDLSRTREETAVQIANLKKNIWLDRGTRATFIDFSVYNANINLFCVVRLLVEFPATGGV
ITSWQFQPVKLIHYISTFDFFLATCEITFCFFILYYIVEEILEIRIHKLHYFRSFWNCLD
IVIIALSIVAIGINIYRKSNVELLLKYLEDQNTFPNLEPLAYWQIQFNNVAAVMVFFVWI
KLFKFINFNRTMSQLSTTMSRCAKDLVGFAIMFLIIFLAYAQLAYLVFGTQVDDFSTFQE
CIFTQFRIILGDFNFTELEEANRVLGPIYFTTFVFFMLFILLNMFLAIINDTYSEVKSDM
AQQKTEMELSDLIRKGCQKAMIKLKLKKNTVDDISESLQQSGGKLNFDELRQDLKGKGHT
DAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDLDLDHSSLPRPMSIRSFPRNLDD
SEEDDDEDSGHSSRRRGSSSSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIME
RAKLKRREVLGRLLDGVTEDERLGRDNEIHREQMERLVREELERWESDDGASQISQRLGT
PVGLNGQPRPRGSRPSSSQSTEGIENGGGNGGASIHG

>Gallus gallus_PKD2(ENSGALP_37340)
MAARGREQLELGRLGEAARAGCCPPSPPLSAWSRDNPGFEPEEEEEGAVAAGPALEMDAE
WGGPAAAPSSVGSGRRQRRIPAEVRGRPPAPPEGSTPLRSAWAKRLARRLRGLWGTRLME
ENNMSRERYLRSVLRELITYVIFLVVLCVLTYGTVSSSMYYYTRVMSQLFLETPVSKMEK
TDFKTLSSMDDFWKFTEGPLLDGLYWDMWYNNKTIAENKSFIYYENLLLGVPRIRQLKVR
NGSCSIPEDLKDEIKDCYDVYSVANEDTAPFGLRNGTAWTYTNEKDLNGSSHWGLLATYS
GAGYYQDLSRTREVTAVQIASLKENLWLDRGTRAAFIDFSVYNANINLFCVVRLLVEFPA
TGGLLTSWQFQPVKLIHYISTLDFFLAACEMVFCLFVLYYMVEEILEIHIHRLHYFRSLW
NCLDILIIVLSVAAIGISIYRTSTVDVILKKLIEDQNSFPNFEPLAYWQIQFNNIAAVTV
FFVWIKLFKFVNFNRTMSQLSTTMSRCVKDVVGFAIMFFIIFLAYAQLAYLVFGTQIDDF
STFQDCIFTQFRIILGDFNFTEVEEANRILGPIYFTTFVFFMFFILLNMFLAIINDTYSE
VKSDMAQQKAEMELSDLIRKGYNKAMVKLKLKKTTVDDISESLRQGGGKLNFDELRQDLK
GKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDLDLDRSSLPHPLSSRSFS
RSLDDSEEDEDEDSGHSSRRRGSSSSGVSYEEFQVLMRRVDRMEHSIGSIVSKIDAVIVK
LEAMERAKLKRRDVLGRLLDGVTEDERLGRDSEIHREQMERLVREELERWESDDTASQMS
HRLGTPLGLNGQPRSRSSRPSSSQSDGIDGGGGNGGNNLHV

>Taeniopygia guttata_PKD2(ENSTGUP_2298)
GLWGTRLMEESNTSREQYLKSILRELITYMVFLVVLCVLTYGTVSSSMYYYTRVMSQLFL
ETPVSKTEKTDFKTLSTMDDFWKFTEGPLLDGLYWEMWYNNKTMAENKSFIYYENLLLGV
PRIRQLKVRNGSCSIPEDLKEEIKDCYDVYSVANEDTAPFGLRNGTAWTYTNEKDLNGSS
HWGLIATYSGAGYYQDLSRTREVTALQIASLKKNLWLDRGTRATFIDFSVYNANINLFCV
IRLLVEFPATGGLVTSWHFQPVRLIHYISTFDFFLAACEMSFCLFVLYYMVEEILEIHIH
RLRYFRSVWNCLDILIIVLSVVAIGISIYRTSTVDMLLKKLLEDQNSFPNFEPLAYWQMQ
FNNIAAVTVFFVWIKLFKFVNFNRTMSQLSTTMSRCVKDVIGFAIMFFIIFLAYAQLAYL
VFGTQIDDFSTFQDCIFTQFRIILGDFNFTEVEEANRILGPIYFTTFVFFMFFILLNMFL
AIINDTFSEVKSDMAQQKAEMELSDLIRKGYNKAMIKLKLKKTTVDDISESLRQGGGKLN
FDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDLDLDRSSLP
RPLSSRSFPRSLDDSEEDEDEDSGHSSRRRGSSSSGVSYEEFQVLMRRVDRMEHSIGSIV
SKIDAVIVKLEAMERAKLKRRDVLGKLLDGVTEDERLGRSSEMHREQMERLVREELERWE
SDDVASQVSHRLGTPLGLNGQPRSRNSRPSSSQSDGVDAGAGNGGNNIHV

>Pelodiscus sinensis_PKD2(ENSPSIP_2396)
MVTDKANHQLDLLLVRDGIPGMAGTQRWPGDCFDVQVCGLWGTRLMEENTSRERYLKSVL
RELITYVIFVVVLCVLTYGMVSSSMYYYTRVMSQLFLETPLSKMEKTNFKTLSTMEDFWK
FTEGPLLDGLYWEMWYNNKTTTENRSFIYYENLLLGVPRIRQLKVKNGSCSIPEDLKDEI
KECYDVYSVANEDTDPFGLQNGTAWIYTSEQDLNGSSHWGLIASYSGAGYYQDLSRSREA
TAAQIANLKKHLWLDRGTRATFIDFSVYNANINLFCIVRLLVEFPATGGLISSWQFQPVK
LTHYISTFDFFLAACEMAFCLFMLYYIVEEILEIHIHKLHYFRSLWNCLDILIIMLSVAA
IGINIYRRSTVDRLLKKQLEDQNTFPNFEPLAYWQIQFNNISAVTVFFVWIKLFKFVSFN
RTMSQLSTTMSRCAKDVIGFAIMFFIIFLAYAQLAYLVFGTQIDNFSTFQDCVFTQFRII
LGDFNFTEVEEANRVFGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDMAQQKAEMEL
SDLIKKGYSKAMIKLKLKKATVDDISENLRQGGGKLNFDELRQDLKGKGHTDAEIEAIFT
KYDQDGDQELTEHEHQQMRDDLEKEREDLDLDRSVLPRPMSGRSFPRSLDDSEEDDDEDS
GHSSRRRGSSSSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKLKRRDV
LGRLLDGVTEDERLGRDNEIHREQMEQLVREELERWESDDTVSRMSHCLGTPVGLNSQPR
SRNSRPSSSQSTEGIDRSGGGNGGSNIHV

>Xenopus tropicalis_PKD2(ENSXETP_61316)
AAPGAPSLQPQDMVELETITRQEPPAPPGGATPSPLSSCSRQAWSRDNPGFDAEEDGMEE
EEDGEEGMVVEMDVEWHPSAGPGRRSSSLVSSSSGGSTGLGGYHHHGQRGRKRRGDPGMG
AGRNGHSTEQPQELEGAGKLLHRVRGLWGTRYTEERITTREKYLKIVFRELITYIVFLVI
VCVLTYSMVTSNMFYYTKGMSQLFLDGPVSKDERTNFKTLLTMDDFWKFTEGPLMDGLYW
DMWYNNRTMAENHSFIYYENLLLGVPRLRQLRVKNGSCSVPEDLKDEIKDCYDSYSVRNE
DTTPFGLRNGTAWTYTKEKDLNGSSQWGVISVYSGAGYYIDLSRNREESAAQIAMLKNNL
WLDRGTRAVFIDFSVYNANLNLFCVVRLLVEFPATGGLITSWQFQTVKLIHYISSFEFFL
AACEIIFCIFILYYIIEEFLEIHVHHLHYFRSLWNWLDIVIIGLSLPAIGIHLYKMSSVE
GPLNKQLSDLNVFPNLESLAYWQIQFNSVAAVIVFFAWVKLFKFANFNRTMTQLSTTMSR
CAKDILGFAIMFFIIFLAYAQFAYLVFGTQIDDFSTFQHCIFTQFRIILGDFDFTEVEEA
NRILGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKTDMAQQKSEMELIDLIKKGCSKAM
VKLKLKKTTVDDISESIRQGGGKLNFDELRQDLKGNGIQSQKMHLILCGFGETQGLGIIS
YEYSEFSIQLNLASHKEDLEMDRGSLPRPMSGRSFPRSLDDSEEDDDEDSGHSSRRRGSS
SSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKLKRREVLGRLLDGVTE
DERLGRDNELHREQMERLVREELERWESDDTVSQMSHRLGTPSGNNGQARSRGSRPPSSQ
STEGIEGGIVTGSTGNSQI

>Danio rerio_PKD2(ENSDARP_27024)
MSSSRVRPQAPQSPAASASASPPPHEGIEMEKMHHEEVGLGVPDETPSSPPTSSSRQAWS
RDNPGFEPEEGMMEADWPPESQGRRSVSTTSSSSSGGVPGNFSGISARINRGLYPTPPAQ
EHRSCGKRILEKMRVLWDTRLLGESNSNREMYLKTVLREMITYILFLLTLCIITYGMVST
NMYYYTKVMSQLFLDTPLSSGEPTNFKSLSTMEDFWKFTEGPFLNGMYWELWYNNKSLPE
NQSLIYYENLLLGVPRLRQLRVRNESCSVHEDLRDEVYDCYNVYSPANEDKAPFGPKNGT
AWRFKDESSLGESSYWGQVSTYGGGGYYQDLSRTREKSANQLQELKNNLWLDRGTRAVFL
DFSIYNGNVNLFCIVRLLVEFPATGGAVPSWQFQTVRLLRYVSSWDYFVGMCEVSFCLFV
LYYLVEEALEIRLHRLRYFKSLWNCLDVLIVALSVPAIIMNICRTSAVSHRLHFLLENHS
TYPNFEPLARLQVHFNNLAAIIVFLSWVKLFKFINFNKTMNQLSTTMSRCAKDLMGFAIM
FFIVFLAYAQLAYLVFGTQVNDFSTFQACIFTQFRIILGDFDFSEIEEADSVLGPIYFTT
FVFFIFMILLNMFLAIINDTYSEVKADMAQQRSEMEITDLIKKSYNRAMVKLKLKKSSIN
DIPDSLQQAAGKLSFDELRQDLRGKGHSDAEIEAIFAKYDLDGDQELTEHEHQQMRDDLE
KEREDLDLEHSSLPRPASGRSFSRSQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLV
RRVDRMEHSIGSIVSKIDAVIVKLEAMERAKMKRRDVLGRILDGVMEDERMGRDPELQRE
QMDRLVRDELERWESDDTMSQVSHHHHQATPIISSAQLRPRSSRPPSSLSNEGPDAAASG
PAHL

>Takifugu rubripes_PKD2(ENSTRUP_29214)
MSSSRVRPQQSPAARMPHGLESGEGIEMENIRHQDLGLGGVIGTPSPPSRQAWSRDNPGF
EHEDGIMEADWPPASPGRRSASTASGSSCSSGLGSFTGGGGGGGTHAPRGGLYPTPTVDT
QQQESHQRRSCMKQILQKIRILWGTELMEDRDSSRERYLRNILREMITYIAFLVTICILT
YGMVSANMYYYTKVMSQLFLDTPLSPGDPATFRSLATMEEFWKFTEGPFLNGMYWEVWYN
NKSLPENQSLIYYENLLLGVPRLRQVKVRNESCSIHQDLKGEVLECYNLYTPSNEDTASF
GPKNGTAWVYASETEVNGSSYWGQVSKYGGGGYYQDLSRTKEESMTKLQLLREHLWLDRG
TRAVFLDFSVYNGNINLFCIVRLLVEFPATGGVLTSWQFQTVRLIRYMSSWDYFVGLCEV
AFSLFILYYIVEEVLEIRIHRLHYFRSLWNCLDVLIIVLSVIAIIMNITRTAMVGKLLKG
LLENHTAHPSFGSLAHLQVQFNNVAAIIVFFSWVKLFKFINLNKTMSQLTTTMSRCAKDL
VGFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQASIFTQFRIILGDFEFSEIEEANPVLG
PIYFTTFVFFIFFILMNMFLAIINDTYSEVKADMSQQRSEMEMTDFIKKGCNKALMKLRL
KKTAVDDITDSLRQAGGKLNLDELRQDLKGKGHTDAEIQAIFAKYDQEGDQELTEHEHQQ
MRDDLEKEREDLELERNSLTRPISGRSFPRTQEDSEEDDDEDSGHSSRRRGSSSGGVSYE
EFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKVKRRDVLGRLLDGVMEDERLGRD
TDAHREQMERLVREELERWECDDMGSQVSHPQPATPVGPRPRPSSSMSTDGLDTVTNGSS
HV

>Tetraodon nigroviridis_PKD2(ENSTNIP_13981)
GAIGTPSPPSRQAWSRDNPGFEPEDAILEADWPPASPGRRSASTASGSSCSSGLGSFTGV
GSSAQLPRGGLIPSPTVDPQQQESHQRRSCMKQILQKIRILWGTELMEDSDSSRERYLRN
ILREMITYIAFLVTVCILTYGMVSANMYYYTKVMSQLFLDMPLSPGDPTTFRTLATMEDF
WKFTEGPFLNGMYWEVWYNNQSLPENQSLIYYENLLLGVPRLRQVKVRNESCSVHQDLLG
EALECYNLYSPSNEDTASFGPKNGTAWVYATETEVNGSSHWGQVSKYGGGGYYQDLSPTR
EGSLVQLQLLKKCLWLDRGTRAVFLDFSVYNGNINLFCIVRLLVEFPATGGVLTSWRFQT
VRLIRYVSSWDYFVGVCEVAFSLFILYYIVEEVLEIRIHRLHYFRSLWNCLDVLIILLSV
VAVIMNITRTATVGNLLKGLLENHAAHPSFESLAHLQVQFNNVAAVIVFFSWVKLFKFIN
LNKTMSQLTTTMSRCAKDLVGFAIMFFIIFLAYAQLAYLVFGTQVGDFSTFQASIFTQFR
IILGDFEFSEIEEASPVLGPVYFTTFVFFVFFILMNMFLAIINDTYSEVKADMSQQRSEM
EMTDFIKKGCNKALMKLRLKKTAVDDITDSLRQAGGKLNFDERQDLKGKGHTDAEIQAIF
AKYDHDGDQELTEHERQQMRDDLEKEREDLELERSSLTRPISGRSFPRTQEDSEEDDDED
SGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKVKRRD
VLGRLLDGVLEDERLGRDADTHREQMERLVREELERWESDDMGSQVSHPSLTTPVGTRPR
PSSSMSTDGLD

>Gasterosteus aculeatus_PKD2(ENSGACP_22905)
TMSSSRVRPQQPPRSQTGRLPRSLDPADGIEMENIQHRDLGLGGVIGTPSPPSRQAWSRD
NPGFEPEEEIMEADWPPASPGRRSVSTASSGSGGGGSPGSFIGAGSSTQIPRGGLYPTPS
GDARQQDRLDHRSCMKQMLQRIRILWGTELMEDSDSSRERYLRNVLREMITYITFLITIC
ILTYGMVSANMYYYTKVMSELFLDTPLSAGDPSTFRSLSTMEDFWKFTEGPFLNGMYWEV
WYNNKSLPENQSLIYYENLLLGVPRLRQLKVRNESCSVHEDLRDEVLDCYNMYTPTNEER
ASFGPKIGTAWVYTAESDMDGGGYVGQISKYGGGGYYQDLSRTKEESAAQLQFLKDQLWL
DRGTRAVFLDFSVYNGNINLFCIARLLVEFPATGGVVTSWQFQTVRLIRYVSSWDYFVGL
CEVAFCLFIVYYMVEEVLEVRIHRLHYFKSLWNCLDVLIVVLSVVAIIMNITRTAMVSSR
LKGLLENHTAHPTFEPLANLQIQFNNMAAVIVFFSWVKLFKFINFNKTMSQLSGTMSRCA
KDLVGFAIMFFIIFLAYAQLAYLVFGTQVNDFSTFQASIFTQFRIILGDFEFSEIMEANP
VLGPIYYTTFAFFIFFILMNMFLAIINDTYSEVKADMSQQRSEMEMTDLLKKGCNKALMK
LRLKKTAVDDISDSLRQAGGKLNFNELRQDLKGKGHTDAEIQAIFAKYDHDGDQELTEND
HQQMRDDLEKEREDLDLERNSLTRPSSGRSFTRTQDDSEEDDDEDSGHSSRRRGSSSGGV
SYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLETMERAVLKRRDVLGRLLDGVMEDERL
GRDADAHSELLERLVREELERCESDDTVSQVSHPQPATPVGPRPRPSSSLSTDGMSTNGS
SHV

>Oryzias latipes_PKD2(ENSORLP_8801)
MSATRVRPQSQAGTDKPPRTLDSSEGIEMENIQHQDPGLGGVAGSPSPPSRQAWSRDNPV
FEPEEEIMQADWPQASPGRRSAFTASGGSSCSSGHGGYTRAGSSTQIPRGGLYPTQTLNG
QQQDRHEHPGCMKRIFQNIRILWGTELMEDGDSNRERYLWNVLRELLTYIAFLITICILT
YGMISTNMYYYTKAMSQLFLDAPLSSENPKTFRSLSTMEDFWKYTQGPFLGGMYWEVWYN
NQSLPGNQSFIYYENILLGVPRLRQVRVHNETCSIHEDLRDEVQGCYGVYTPSNEDNSPF
GPQNGTAWVHTTESKMNASTHWGQVSKYGGGGYYQDLSRTREESGLQLQFLKDHLWLDRG
TRAIFLDFSVYNGNVNLVCIARLLVEFPATGGVLTSWQFQTLRLIKYVSSWDYFVGVCEV
AFCLFVLYYVVEEVLEIHIHRLHYFKNLWNCLDVLIVTLSVVAIIMSITRAAMGGDLLKG
LENYTSHTSFDSLANLQVQFNNMAAVIVFFCWVKLFKFINFNKTMSQLSTTMSRCAKDLV
GFAIMFFIIFLAYAQLAYLVFGTQVNDFSTFQGSVFTQFRIILGDFDFFEIKEANPVLGP
IYFITFVLFIFFILMNMFLAIINDTYSEVKADMAQHRSEMEMTDFIKKGCTKALVKLRLK
KTTVDDISDSLRQAGGKLNYDELLQDLKEKGHTEAEIQAIFAKYDQDGDLELTEHDHQQM
RDDLEKEREDLDLERNSLTRPSSGRSFPRTQDDSEEDDDEDSGHSSRRRGSSSGGVSYEE
FQQRLVRRVDRMEHSIGSIVSKIDAVIVKLEGMERAKLKRRDVLVRLLDGVMEDERLGRD
ADTHREQMERLVKEELERWETDDVASQVSHPQPATPIGPRPRPPSSLSTDGLDTSANGGT
HV

>Homo sapiens_PKD1L1(ENSP_289672)
MAEEAAQNISDDQERCLQAACCLSFGGELSVSTDKSWGLHLCSCSPPGGGLWVEVYANHV
LLMSDGKCGCPWCALNGKAEDRESQSPSSSASRQKNIWKTTSEAALSVVNEKTQAVVNEK
TQAPLDCDNSADRIPHKPFIIIARAWSSGGPRFHHRRLCATGTADSTFSALLQLQGTTSA
AAPCSLKMEASCCVLRLLCCAEDVATGLLPGTVTMETPTKVARPTQTSSQRVPLWPISHF
PTSPRSSHGLPPGIPRTPSFTASQSGSEILYPPTQHPPVAILARNSDNFMNPVLNCSLEV
EARAPPNLGFRVHMASGEALCLMMDFGDSSGVEMRLHNMSEAMAVTAYHQYSKGIFFHLL
HFQLDMSTYKEAETQNTTLNVYLCQSENSCLEDSDPSNLGYELISAFVTKGVYMLKAVIY
NEFHGTEVELGPYYVEIGHEAVSAFMNSSSVHEDEVLVFADSQVNQKSTVVIHHFPSIPS
YNVSFISQTQVGDSQAWHSMTVWYKMQSVSVYTNGTVFATDTDITFTAVTKETIPLEFEW
YFGEDPPVRTTSRSIKKRLSIPQWYRVMVKASNRMSSVVSEPHVIRVQKKIVANRLTSPS
SALVNASVAFECWINFGTDVAYLWDFGDGTVSLGSSSSSHVYSREGEFTVEVLAFNNVSA
STLRQQLFIVCEPCQPPLVKNMGPGKVQIWRSQPVRLGVTFEAAVFCDISQGLSYTWNLM
DSEGLPVSLPAAVDTHRQTLILPSHTLEYGNYTALAKVQIEGSVVYSNYCVGLEVRAQAP
VSVISEGTHLFFSRTTSSPIVLRGTQSFDPDDPGATLRYHWECATAGSPAHPCFDSSTAH
QLDAAAPTVSFEAQWLSDSYDQFLVMLRVSSGGRNSSETRVFLSPYPDSAFRFVHISWVS
FKDTFVNWNDELSLQAMCEDCSEIPNLSYSWDLFLVNATEKNRIEVPFCRVVGLLGSLGL
GAISESSQLNLLPTEPGTADPDATTTPFSREPSPVTLGQPATSAPRGTPTEPMTGVYWIP
PAGDSAVLGEAPEEGSLDLEPGPQSKGSLMTGRSERSQPTHSPDPHLSDFEAYYSDIQEA
IPSGGRQPAKDTSFPGSGPSLSAEESPGDGDNLVDPSLSAGRAEPVLMIDWPKALLGRAV
FQGYSSSGITEQTVTIKPYSLSSGETYVLQVSVASKHGLLGKAQLYLTVNPAPRDMACQV
QPHHGLEAHTVFSVFCMSGKPDFHYEFSYQIGNTSKHTLYHGRDTQYYFVLPAGEHLDNY
KVMVSTEITDGKGSKVQPCTVVVTVLPRYHGNDCLGEDLYNSSLKNLSTLQLMGSYTEIR
NYITVITRILSRLSKEDKTASCNQWSRIQDALISSVCRLAFVDQEEMIGSVLMLRDLVSF
SNKLGFMSAVLILKYTRALLAQGQFSGPFVIDKGVRLELIGLISRVWEVSEQENSKEEVY
RHEEGITVISDLLLGCLSLNHVSTGQMEFRTLLHYNLQSSVQSLGSVQVHLPGDLAGHSP
AGAETQSPCYISQLILFKKNPYPGSQAPGQIGGVVGLNLYTCSSRRPINRQWLRKPVMVE
FGEEDGLDNRRNKTTFVLLRDKVNLHQFTELSENPQESLQIEIEFSKPVTRAFPVMLLVR
FSEKPTPSDFLVKQIYFWDESIVQIYIPAASQKDASVGYLSLLDADYDRKPPNRYLAKAV
NYTVHFQWIRCLFWDKREWKSERFSPQPGTSPEKVNCSYHRLAAFALLRRKLKASFEVSD
ISKLQSHPENLLPSIFIMGSVILYGFLVAKSRQVDHHEKKKAGYIFLQEASLPGHQLYAV
VIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQLGLLR
KIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVERELTCLQGGLG
FRKLFYCKFTEYLEDFHVWLSVYSRPSSSRYLHTPRLTVSFSLLCVYACLTALVAAGGQE
QPHLDVSPTLGSFRVGLLCTLLASPGAQLLSLLFRLSKEAPGSARVEPHSPLRGGAQTEA
PHGPNSWGRIPDAQEPRKQPASAILSGSGRAQRKAASDNGTACPAPKLQVHGADHSRTSL
MGKSHCCPPHTQAPSSGLEGLMPQWSRALQPWWSSAVWAICGTASLACSLGTGFLAYRFG
QEQCVQWLHLLSLSVVCCIFITQPLMVCLMALGFAWKRRADNHFFTESLCEATRDLDSEL
AERSWTRLPFSSSCSIPDCAGEVEKVLAARQQARHLRWAHPPSKAQLRGTRQRMRRESRT
RAALRDISMDILMLLLLLCVIYGRFSQDEYSLNQAIRKEFTRNARNCLGGLRNIADWWDW
SLTTLLDGLYPGGTPSARVPGAQPGALGGKCYLIGSSVIRQLKVFPRHLCKPPRPFSALI
EDSIPTCSPEVGGPENPYLIDPENQNVTLNGPGGCGTREDCVLSLGRTRTEAHTALSRLR
ASMWIDRSTRAVSVHFTLYNPPTQLFTSVSLRVEILPTGSLVPSSLVESFSIFRSDSALQ
YHLMLPQLVFLALSLIHLCVQLYRMMDKGVLSYWRKPRNWLELSVVGVSLTYYAVSGHLV
TLAGDVTNQFHRGLCRAFMDLTLMASWNQRARWLRGILLFLFTLKCVYLPGIQNTMASCS
SMMRHSLPSIFVAGLVGALMLAALSHLHRFLLSMWVLPPGTFTDAFPGLLFHFPRRSQKD
CLLGLSKSDQRAMACYFGILLIVSATLCFGMLRGFLMTLPQKRKSFQSKSFVRLKDVTAY
MWEKVLTFLRLETPKLEEAEMVENHNYYLDEFANLLDELLMKINGLSDSLQLPLLEKTSN
NTGEARTEESPLVDISSYQAAEPADIKDF

>Pan troglodytes_PKD1L1(ENSPTRP_32759)
MAEEAAQNISDDQERCLQAACCLSFGGELSVSTDKSWGLHLCSCSPPGGGLWVEVYANHV
LLMSDGKCGCPWCALNGKAEDRESQSPSSSASRQKNIWKTTSEAALSVVNEKTQAPLDCD
NSADRIPHKPFIIIARAWSSGGPRFYHRQLCATGTADSIFSGLLQLQGTTSAAAPCSLKM
EASCYVLRLLCCAEDVATGLLPGTVTMETPTKVARPTQTSSQRVPLWPISHFPTSPKSSH
GLPPGIPRTPSFTASQSGSEILYPPTQHPPVAILARNSDNSMNPVLDCSLEMEARAPPNL
GFRVHMASGEALCLMMDFGDSSGVEMRLHNMSEAMVVTAYHQYSKGNFFHLLHFQLDMST
YKEAETQNTTLNVYLCQSENSCLEDSDPSNLGYELISAFVTKGVYMLKAVIYNEFHGTEV
ELGPYYVEIGHEAVSAFMNSSSVHEDEVLVFADSQVHQKSTVVIHHFPSIPSYNVSFISQ
TQVGDSQAWHSMTVWYKMQSVSVYTNGTVFATDTDIIFTAVTKETIPLEFEWYFGEDPPV
RTTSRSIKKRLSIPQWYRVTVKASNRISSVVSEPHIIRVQKKIVANRLTSPSSALVNASV
AFECWINFGTDVAYLWDFGDGTISLGSSSSSHVYSREGEFTVEVLAFNNVSASTLRQQLF
IVCKPCQPPLVKNMGPGKVQIWRSQPVRLGVTFEAAVFCDISQGLSYTWNLMDSEGLPVS
LPAAVDTRRQTLILPSHTLEYGNYTALAKVQIEGSVVYSNYCVGLEVRAQAPVSVISEGT
HLFFSRTTSSRIVLRGTQSFDPDNPGATLRYHWECATAGSPAHPCFDSSTGHQVDAAAPT
VSFEAQWLSDSYDQFLVMLRVSSGGRNSSEARVFLSPYPDSAFRFVHISWVSFKDTFVNW
NDELSLQAMCEDCSEIPNLSYSWDLFLVNATEKNRIEVPFCRVVGLLGSLGLGAISESSQ
LNLLPTEPGTADPDATTTPFSQEPSPVTLGQPAPSAPRGTPTEPMTGVYWIPPAGDSAVL
GEAPEEGSLDLEPGPQSKGSLMTGPSERSQPTHSPDPHLSDFEAYYSDIQEAIPSGGRQP
AKDTSFPGSGPSLSAEESPGDGDNLLDPSLSAGRAEPVLMIDWPKALLGRAVFQGYSSSG
ITEQTVTIKPYSLSSGETYVLQVSVASKHGLLGKAQLYLTVNPAPRDMACQVQPHHGLEA
HTVFSVFCMSGKPDFHYEFSYQIGNTSKHTLYHGRDTQYYFVLPAGEHLDNYKVMVSTEI
TDGEGSKVQPCTVVVTVLPRYHGNDCLGEDLYNSSLKNLSTLQLMGSYTEIRNYITVITR
ILSRLSKEDKTASCNQWSRIQDALISSVCKLAFVDQEEMIGSVLMLRDLVSFSNKLGFMS
AVLILKYTRALLAQGQFSGPFVVDKGVRLELIGLISRVWEVSEQENSKEEVYLHEEGITV
ISDLLLGCLSLNHVSTGQMEFRTLLHYNLQSSVQSLGSVQVHLPGDLAGHNPAGAETQSP
CYISQLILFKKNPYPGSQAPGQIGGVVGLNLYTCSSRRPINRQWLRKPVMVEFGEEDGLD
NRRNKTTFVLLRDEVNLHQFTELSENPQESLRIEIEFSKPVTRAFPVMLLVRFSEKPTPS
DFLVKQIYFWDESIVQIYIPAASQKDASVGYLSLLDADYDRKPPKRYLAKAVNYTVHFQW
IRCLFWDKREWKSERFSPQPGTSPEKVNCSYHRLAAFALLRRKLKASFEVSDISKLQSHP
ENLLPSIFIMGSVILYGFLVAKSRQVDHHEKKKASYIFLQEASLPGHQLYAVVIDTGFRA
PARLTSKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQLGLLRKIRLWHDS
RGPSPGWFISHVMVKELHTGQAWFFPAQCWLSAGRHDGRVERELTCLQGGLGFRKLFYCK
FTEYLEDFHVWLSVYSRPSSSRYLHTPRLTVSFSLLCVYACLTALVAAGGQEQPQLDVSP
TLGSFRVGLLCTLLASPGAQLLSLLFRLSKEAPGSARVEPHSPLRGGAQTEAPHGPNSWG
RIPDTQEPCKQPASAILSGSGRAQRKAASDSGTACPAPKLQVHGADHSRTSLMGKSHCCP
PHTQAPSSGLEGLMSQWSRALQPWWSSAVWAICGTASLACSLGTGFLAYRFGQEQCVQWL
HLLSLSVVCCIFITQPLMVCLMALGFAWKRRADNQFFTESLCEATRDLDSELAERSWTRL
PFSSSCSTPDCAGEVEKVLAARQQARHLRWAHPPSKAQLRGTRQRMRRESRTRAALRDIS
MDILMLLLLLCVIYGRFSQDEYSLNQAIQKEFTRNARNSLGGLRNIADWWDWSLTTLLDG
LYPGGTPSARVPGAQPGALGGKCYLIGSSVIRQLKVFPRHLCKPPRPFAALIEDSIPTCS
PEVGGPEDPYLIDPENQNMTLNGPGGCGAREDCVLSLGRTRTEAHTALSRLRASMWIDRS
TRAVSVHFTLYNPPTQLFTSVSLRVEILPTGSLVPSSLVESFSIFRSDSALQYHLMLPQL
VFLALSLIHLCVQLYRMMDKGVLSYWRKPRNWLELSVVGVSLTYYAVSGHLVTLAGDVTD
QFHRGLCRAFMDLTLMASWNQRARWLRGILLFLFTLKCVYLPGIQNTMASCSSMMRHSLP
SIFVAGLVGALMLAALSHLYRFLLSMWVLPPGTFTDAFPGLLFHFPRRSQKDCLLGFSKS
DQRDMACYFGILLIVSATLCFGMLRGFLMTLPQKRKSFQSKSFVRLKDITAYMWENILTF
LRLETPKLEEAEMVENHNYYLDEFANLLDELLMKINGLSDSLQLPLLEKTSNNTGEARTE
ESPLVDISSYQAAEPADVKDF

>Gorilla gorilla_PKD1L1(ENSGGOP_9861)
MAEEAAQNISDDQERCLQAACCLSFGGELSVSTDKSWGLHLCSCSPPGGGLWVEVYANHV
LLMSDGKCGCPWCALNGKAEDRESQSPSSSASRQKNIWKTTSEAALSVVNEKTQAVVNEK
TQAPLDCDNSADRIPHKPFIIIARAWSSGGPRFHHRRLCATGTADSTFSGLLQLQGTTSA
AAPCSLKMEASCCVLRLLCCAEDVATGLLPGTVTMETPTKVARPTQTSSQRVPLWPISHF
PTSPRSSHGLPPGIPHTPSFTASQSGSEILYPPTQHPPVAILARNSDNSMNPVLNCSLEM
EARAPPNLGFRVHMASGEALCLMMDFGDSSGVEMRLHNMSEAMAVTAYHQYSKGKFFHCL
HFQLDIGLFHLPPFGITVLDVSLQWTWLCCVNHSDHSYLRYVSHSVFLTEGVYMLKAVIY
NGFHGTEVELGPYYVEIGHEAVSAFMNSSSVHEDEVLVFADSQVNQKSTVVIHHFPSIPS
YNVSFISQTQVGDSQAWHSMTVWYKMQSVSVYTNVTVFATDTDIIFTAVTKETIPLEFEW
YFGEDPPVRTTSRSIKKRLSIPQWYRVMVKASNRISSVVSEPHVIRVQKKIVANRLTSPS
SALVNASVAFECWINFGTDVAYLWDFGDGTVSLGSSSSSHVYSREGEFTVEVLAFNNVSA
STLRKQLFIVCEPCQPPLVKNMGPGKVQIWRSQPVRLGVTFEAAVFCDISQGLSYTWNLM
DSEGLPVSLPAAVDTRRQTLILPSHTLEYGNYTALAKVQIEGSVVYSNYCVGLEVRAQAP
VSVISEGTHLFFSRTTSSPIVLRGTQSFDPDNPGATLRYHWECATAGSPAHPCFDSSTAH
QLDAMAPTVSFEAQWLSDSYDQFLVMLRVSSGGRNSSEARVFLSPYADSAFRFVHISWVS
FKDTFVNWNDELSLQAMCEDCSEIPNLSYSWDLFLVNATEKNRIEVPFCRVVGLLGSLGL
GAISESSQLNLLPTEPGTADPDATTTPFSREPSPVTLGQPAPSAPRGIPTEPMTGVYWIP
PAGDSAVLGEAPEEGSLDLEPGPQSKGSLMTGPSERSQPTHSPDPHLSDFEAYYSDIQEA
IPSGGRQPAKDTSFPGSGPSLSAEESPGDGDNLVDPSLSAGRAEPVLMIDWPKALLGQAV
FQGYSSSGITEQTVTIKPYSLSSGETYVLQVSVASKHGLLGKAQLYLTVNPAPRDMACQV
QPHHGLEAHTVFSVFCMSGKPDFHYEFSYQIGNTSKHTLYHGRDTQYYFVLPAGEHLDNY
KVMVSTEITDGEGSKVQPCTVVVTVLPRYHGNDCLGEDLYNSSLKNLSTLQLMGSYTEIR
NYITVITRILSRLSKEDKTASCNQWSRIQDALISSVCKLAFVDQQRLHDMVSWLALLRDY
INSSEKLGFMSAVLILKYTRALLAQGQFSGPFVVDKGVRLELIGLISRVWEVSEQENSKE
EVYLHEEGITVISDLLLGCLSLNHVSTGQMEFRTLLHYNLQSSVQSLGSVQVHLPGDLAG
HNPAGAETQSLCYISQLILFKKNPYPGSQAPGQIGGVVGLNLYTCSSRRPINRQWLRKPV
MVEFGEEDGLDNRRNKTTFVLLRDKVNLHQFTELSENPQESLQIEIEFSKPVTRAFPVML
LVRFSEKPTPSDFLVKQIYFWDESIVQIYIPAASQKDASVGYLSLLDADYDRKPPNRYLA
KAVNYTVHFQWIRCLFWDKREWKSERFSPQPGTSPEKVNCSYHRLAAFALLRRKLKASFE
VSDISKLQSHPENLLPSIFIMGSVILYGFLVAKSRQVDHHEKKKAGYIFLQEAPLPGHQL
YAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQLG
LLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSASRHDGRVERELTCLQG
GLGFRKLFYCKFTEYLEDFHVWLSVYSRPSSSRYLHTPRLTVSFSLLCVYACLTALVAAG
RQEQHQLDVSPTLGSFRVGLLCTLLASPGAQLLSLLFRLSKEAPGSARVEPHSPLRGGAQ
TEAPHDPNSWRRVPDAQEPCKQPASAILSGSGRAQRKAASDNGTACPAPKLQVHGADHSR
TSLMGKSHCCPPHNQAPSSGLEGLMPQWSRALQPWWSSAVWAICGTASLACSLGTGFLAY
RFGQEQCVQWLHLMSLSVVCCVFITQPLMVCLMALGFAWKRRADNHFFTESLCEATRDLD
SELAERSWTRLPFSSSCSIPDCAGEVEKVLAARQQARHLRWANPPSKAQLRGTRQRMRRE
SRTRAALRNIAAEIMFVRSLRCTVFILWSSLDLVLDQAFNFLALRNARNSLGGLRNITDW
WDWSLTTLLDGLYLGGTPSARVPGAQPGALGGKCYLIGSSIIRQLKVFPSHLCKPPRPFS
ALIEDSIPTCSPEVGGPENPYLIDPENQNVTLNGPGGCGAREDCVLSLGRTRTEAHTALS
RLRASMWIDRSTRAVSVHFTLYNPPTQLFTSVSLRVEILPTGSLIPSSLVESFSIFRSDS
ALQYHLMLPQLVFLALSLIHLCVQLYRVMDKGVLSYWRKPRNWLEFSVVGVSLTYYAVSG
HLVTLAGDVTDQFHRGLCQAFMDLTLMASWNQRARWLRGILLFLFTLKCVYLPGIQNTMA
SCSSMTRHSLPSIFVAGLVGALMLAALSHLHRFLLSVWVLPPGTFTDAFPRLLFHFPRRS
QKDCLLGLSKSDQRAMACYFGILLIVSATLCFGMLRGFLMTLPQKRKSFQSKSFVRLKDV
TAYMWEKVLTFLRLETPKLEEAEMVENHNYYLDEFANLLDELLMKINGLSDSLQLPLLEK
TSNNTGEARTEESPLVDISSYQAAEPTELKLF

>Mus musculus_PKD1L1(ENSMUSP_120803)
XFSNPPPGISHTCNLSASWYHPESSSPLTQHPPRATLVTQPENVEHFAICCFPETDAQAL
PALGIRVHVASGTALCLLLDFGDNCGAQMRLCTLAGATTVTGYHQYRKEGVYELKAVVHD
FHRAEELGPYYVDISHGNVSVFMNSSSIHDSEALSFADSLPQQRGTVVVHCFSSISSYNV
SFISQTQVASGQAWCGVTVGYKMQSVSVYTNGTVFAANTNITFVAITEETIPLEFAWYFG
ENPPVMTTSRSIRRRLSVPQWYRVKVKATSRIGSVVSEPHLIRVQKRIMANRLVSTASAL
VNANVSFECRLNFGTDVAYLWNFGDDTIELGSSSSSHVYSREGEFTVEVLAFNNVSSTTL
RKQLFIVREPCQPPPVKNMGPAKVQIWRSQPLRLGVTFEAAILCNISQGLSYTWSFVSAE
MTTVTLPTAVNTRRQTIMLPSYTLECGNYTAIAKVQIKGSMVYSNYCVGVEVRARAPVSV
ISEGTHIFISTATSTFIILRGAQSYDPDNPGAALRYHWTCTAASSPRWPCFDNSTSYQVD
TQAPAISFPAKWLSECCDQFLVTLTVSSRGQNSSQALMFLSTRPDLAFRFVHISWVNFRD
ISVNWNEEVSLRAVCEDCGDVPDLTYSWDLFLVNATEKSAVEVPFCSTVGLLGALALGTS
LKSSKSDLPSNLRAPLTPHSPEPSPTPLGWTALSNLGSISAESTAGGHHVPASGAVAGSG
EPMEEYSSLSSLAEEALMTNSSEGSWPSPSSSTDFDDFEAYYSDIQEAVLSLGRQPGTST
NFQEAGPSLSAEESASYGDNLLGPFLHTGRAKPTLMIDWPKALVSQAAFHGYTTSGIMGP
AVTIKPFSLSSGKTYVLQASVASKHVLLGKAQLYLTVNQAPQDMSCQVRPHHGMEAYTIF
SVFCMSGKPDFHYEFRYRIGNTSSHTLYRGQDTQHYFLLPAGDSSDNYKVIVSTEITDGH
GSKVQPCTVAVTVLPRYHGNDCCDKELYNSTLESLSTLRLAGSYMETRNYITMITGILSR
LYVESRNTSSCGQWSQIQDVLISSACKVPYTDQEGMMDSIHILRDLISFPNKLSLTSAMC
IFKYTKMFLAQGQFSRRLLVDKKLRVEFVLLISGVWEAAKEDARDGDYLQEEGMKIISDM
LLIHVSTGQMEFQTLLHRSPQSSIQNLGFVQVHFPSDLASLHSTTQEATQSSCYISQLMF
FMKSPYLGGQVPGQVGGVMIPRLYSCESRRPILRGQLETPVTMEFGEEDYLHKRNPAMFV
LLRDEVNVHRFTGLSENSQESLQIHIKFSKPVTRPFPIILLVRFSEKATPSDFLVKRVYF
WDEQTVQMYVPAAPWKGANVGYLSLLDADYDRKPPNKYLAGAVNYTVHFQWIQCVFWDKT
EWRSEGPYPQPGSSPEKVNCSYHHLAPVSVLRRKLNATLEVSSISEFQSHPHNLLPGIFS
AFLLVLYGILVSKSRYVDCHEKKNPGFIFLEEDTLPGYQLYAVVIDTGFRSPVRFTSKVF
IVLCGENGCSETKELCCPEKPLFGRNSRHTFILSIPNQLGPLQKIRLWHDSSGSSPCWFI
SHVMVKELCSGQAWFFSAQCWLAVSKLGGHVLREFFCLSHGLGFWKLFYSKFTEYLEDFH
IWLSLYSQPPSRSYLHTQRLAVSFCLLCVYSCLTALVTVRDHQQRPLDVGPTAITLEPFC
MALLCTLLACPVAQLLSLLFRCSKEARGDMQASTQWPLRGVKTETPQGHDSSGRPDSRQP
SPHPTSDLLPWNDQAWRIAASSSAVVCSPFPMEACSHKHHDLREKSHYSPPSSQAPGSGF
EELGSQKSRVCLLWSSSVAWAISGSASLACGLGTGFLGYWFVPAQCMWWLYLLLLSLVCC
AFITQPLMICLAALVFAWKRKHDSKFFTESLQDATKGLDLELEEHSRTRVPLSPISYSPD
TAEEAERVLATRQRERHLRWAQTPSKAKLRVTGERLRRESIMQAALRDMTTHSIMLLLLL
FIAYGRFCPGEISLNHAIRKAFTRKANHSLGDLSSTEDWWDWTLSTLLDELYPERTSARA
WGAQPGALGGQCHLIGPPVVKLLKISAGTACTPPRPFSELVEDVLPMHSNDLDLENQNVS
PGGPETCGVKKESYMHSLGKTRHEAHAALTALRASKWIDHSTRAMSVHFTLYNPPTQLFT
SVILGTECLPSGGLVPSFLVESFRIFYSDSALKYLLMLSELLFLVLNVIHLCFQLWGMTT
KGILSYWRKPRHWLELSMVGVAIAYYAASGHLTTLAVNITDQFHKGLYQRLVDIGLMVSW
HQRARCLQGILLFLWMLKYVHLLSSLSTMTPFSAVTCFPLFRVLLVGALLLAAHYHSRWF
LLFTGTLSHGTSAEAFPGLLLQFPGRSKKDSWHNCLKSDHGVMRCYYGTLFLLLATLGFR
MLRATFLTVFQNRKSSHRKPLVTLKDIAVYTWHKVLTLLGLETTLEETEVATDHIYYLDE
FSSLLDELLMKIDGLSDSLELSILENQWKRALESRAGDSPPVGSSEYQATGVSGPLAAES
E

>Rattus norvegicus_PKD1L1(ENSRNOP_6498)
FSDPPPGISQTRNLSASWYHPESSCPLTQHPLGAVLATQPENAGHFATCCFPETDAKAPP
ALGIRVHAASRTALCLLLDFGDNHGAEMKLSTVTGAATMTGYYQYRTEGVYKLKVVVSDC
HGADEELGPYYMDIGHGNVSVFMNSSSIHNNESLAFANSLPQQEGTVVVHCFSSVSSYNV
SFMSQTRVGSSQAWSGVTVGYTMQSVSVYTNGTVFAADTNITFVAVTEETVPLEFTWYFG
ENPPVTTTSRSIRRRLSIPQWYRVMVKATSRMGSVVSEPHLIRVQKRILANRLVSTASAL
VNANVSFECRLNFGTDVAYLWNFGDGSIELGSSSSGHVYDREGEFTVEVLAFNNISSATL
RKQIFIVQEPCQPPPVKNMGPAKVQIWRSQPLRLGVTFEAAIICNISQGLSYTWSFVGAE
ATAVTLPAAVNTHRQTIMLPSYTLECGNYTAVAKVQIKGSMVYSNYCVGVEVRARAPVSV
ISEGTHIFLSKATSTSIILSGSQSYDPDNPGAALRYHWTCTAASSPIWPCFDDSTSYQMD
TQAPAISFPAKWLSECCDQFLVTLTVSSSGRNSSQALTFLSTRPDLAFRFIHVSWVNFRD
ISVNWNEEVSLRAVCEDCGDVSDLTYSWDLFLVNATEKNAVEVPFCSTVGLLGASALGAS
LKSFESHQPSNVRASPTPHSLGPSPTPLGWTALSNLGSISAESPAGGHHIPAAGPVAGSG
EPMEDYGSLSPAPSSLAEEALMMSDPEGSWPFPSSSTAFDDFEAYYSDIQEAVPSLGRQP
GISANFQEAGSSLSAEESASYGDNLLGPFLHTGRAKPTLMIDWPKALVSRAVFHGYTTSG
IMGPDVTIKPFSLSSGEMYVLQASVASKHVLLGKAQLYLTVNQAPQDMSCQVRPHRGMEA
HTIFSIFCMSGKPDFHYEFRYRIGNASSHTLYRGQDTQYYFLLPAGDSSDSYKVIVSTEV
TDGQGSKVQPCTVEVTVLPRYHGNDCHDKDLYNSTLENLSTLQLVGSYTEIRNYIAMITG
ILSRLYVESRNTSSCGQWSQIQDVLIFSACKVPYTDQETMMDSIHILRDLISFPNKLSLM
SAELIYKYAQMFLAQGQVSRRLLVDEKLRVEFILLISGVWEAAKEDVRDGYYLQKEGMKI
VSDMLLIHISTGQMEFQTLVHRSPQSSIQNLGFIRVHLPNDVALHSPTQEETQSPCYISQ
LTFFMKSPYSGEQAPGQLGGVMSPWLYSCKSRRPILRGRLETPVTIEFGEEDHLHKKNPA
MFVLLRDEVNVHQFTGLSENSQESLQIHIEFSKPVIRAFPIILLVRFSEKATPSDFLMKQ
VYFWDEQTVQMYVPAAPWRGANVGYLSLLDADYDRKPPNKYLAGAVNYTVHFQWIQCVFW
DKTEWRSEGPCPQPGTSPEKVNCSYHRLAPFSVLRRKLNATFQVSSVSEFQSHPHNLLPS
IFSVFFLVLYGFLMSKSSCVDCHKKKDPGCIFLEEEALLGHQLYAVVIDTGFRSPARFTS
KVFIVLCGENGHSETKELCCPEKPLFGRNSRHTFILSTPHQLGPLQKIRLWHDSSGLSPS
WFISHVMVKELCSGQAWFFSAQCWLAVSKRGGQVLGEFFCLSHGLSFWKLFYSKFTEYLE
DFHIWFSLYSQPPSSNYLHTQRLAVSFCLLSVYSCLTALVTVGGHEQRPLGVGPTAITLD
SFSLALLCTILACPPAQLLSLLNLFASQEARGHLRTSRQWPLRGVKTEVPQGPDPGGKPD
SRQPSPHPISDLLPGTDQAWRMTASNSGIVHSSFPLEACRDKHLALRERSHCSPPSSQAP
SSGFEELRPQQSRVCLLWSSSVAWAISGTASLACGLGTGFLGYKFVPAQCVWWLHLLLLS
LVCCALITQPLMICLAASAFAWKRKHDSEFFTESLQDATKGLDLELEERSRTHIPLSPVS
YSPDSAEEAERVLAARQRERHLRWAQTPSGPKFRVMRERLRRERLMQAALRDVTMHSVML
LLLLFIAYGRFCPGEYSLNQAIRRAFTRNAHHSLGDLSSTEDWWDWTLSTLLDGLHPERM
PATAWGSQPGALGGQCHLIGPSVIKQLKVSAGTACVAPKPFSELVEDVLPMHSHALDLEN
RNVTPDDPKTCGVKKESYTHSLGRTRHEAHAALTALRASRWIDHSTRAVSVHFTLYNPPT
RLFTSVTLGAEFLSTRGLVSSSLIESFSIFYRDSALQCLLMLSELLFLVLNMIHLCFQLW
EMATKGILSYWRKPRQWLELSMVGVALAYCAASGHLTTLAENITDQFHKGLYQRFVDISL
MVSWNQRARCLQGILLFLWMLKCVHLFSSLSTMAPFSAVTCSLLFRVLMPTLVGALLLAA
HSHLRWFLLYTSTLSRGTSAEAFPGLLLQFPGRSQKDSQHNHLESDHRAVNCYYGTLFLL
LATLGFRMLRATSLTLFQDRKSFHRKSLVTLKDVAVSMWHRLLTFLRLETTTSGETEVTT
DHIYYLDEFSSLLDELLMKIDGLSDSLELSILEKQWRRTVESRTGDSPSVGILEYQAAGC
STPLFLRSE

>Canis familiaris_PKD1L1(ENSCAFP_40839)
PSVTITSFWNSSGPDPCRPRKCAVGPGSSVPCGLLQELQRSCPPAGPCRLRVRIPSCPSA
DDVPSDVLPGTDVASTAASPGVPVRPAVSAPTSSPTAHPPTLPRSCPASPHSSLGHGGSA
SWPRPPTRCHPGAVSMHSPPDALDAADHGFPDTDARAPLSLGFRVRASPKAALCLQVDFG
DSSGVQVTIYNVSRGIAVTAYHQFRKVMCFLHFFHWPRECARLHPLGPRAMSERGALCEQ
ELSDARDRGASQRCCTLPASCAWQGVYVLKALIYNDLCGPGRELGPYYVEMGPATMSVFM
NSSSIRRDELLVFAGSHADQKSTVVTHHFAAGPPCNVSFTCQSCAAGGQAWPSVTVQYRM
QPVSVYTNGTMFATDIDITFLAVMDERHPLPFSGVRGPLPTSDLSDLLLSPPGPVHGSHC
RYSVTVQAASRLGRVASEPRRIRTQRRIVANRLVSPLSALLNASVTFTCRLNFGTNVAFL
WDFGDGTVGPGGSSAHHTYQREGQFTVQVRAFNDVSAVSLAKQLFVVREPCQPPPVKNMG
PGKVQVWRSQPVTLGVTFESAILCDISQGLSYTWTIRTSEGWPVPLPPGVSTRRQTITVP
GYFLELGNYTALARVQVDGSVVHSNYSVGVEVRARAPVSVISEGTQLFISRAPSVTIILS
GSQSYDPDNPGATLRYHWTCTAAGAPGEPCFTASSPHSLRAGAPSLSFPASSLSNSYDQF
LVTLTVSSAGRNSSEAQVFLSPRPDTALRFVHISRGSFKDALVNWNEELSLRAECDACAA
GPRLSYSWDLFLVNATEGTRTDGPFCRAVGLLGAAGLGADSMQLPSSAPSTAASCPEPRG
TGVASSQKQSPQPRVQPGPSLPGTPSLGPVDTHPLPDAGDAAFPGLARRFAGSPGTWSPW
SPSPSPSAAWQMSPPQGPRASDFEADYGDIQEAVPPTGRQPAHWSGASLPGADPSSSPGG
GQGDGDNLLGPLRPAAGPALMVDWPKAPVGRALFRSYTASGITGHAVTIKPFSLSPGETY
VVQASVASTRGLLGRAQLYLTLHPAPRDVACQVQPHRGLEAHTVFSIFCMAMRPDFRYKF
SYRIGNASKHTLYHGRDTQYYFVLPAGEPSDNYKVMVSTEITDGVGSRTLPCAVAVTVLP
HFHGSLCLDEDTYNSSLKHLSTLQLMGSYTKIRNYITTITRVLSRWAAEDRSPSCGQWSR
IQDALISSACGLPVADQEDMTHSVLMLRGLLRFPRKLSFRSAALILKSARAPLAQSPLSG
RLAVDKGLMLELILLISEVLEASDWEKPRNSGFLQEEGTKIISDLLLDGLSASTEHQLHV
SAGQMEFRTRLHHDLQSSVQSLGSVQVHLPADLAAQSPVGAVQGPCYISQLMLFKKNLYP
WGQGPGQQIGQVVSASLFGCSSRRPVGGWRLRAPVAVEFGEEGGLDNGRTRTAFVLLRDR
VNVHEFTGAATPRESLHIRIEFFRPPSGAFPVMVLVRFSEKPTPAFLVKKVYVWDEQPVH
LHIPAGPLRDLSLGYLSLLDADYDRSPRNRYSAKAVNYTVRFHWLQCVVWEAGEWRPASS
SPQPGVSPGKVNCSHDRLAPVSISRRSPNATFSASDISKLQRHPENLLPGVLIVVFTILY
ALLVTKSRRVDCHERKKAGYIFLQEDAPPGHQLYAVVVDTGFRSPTRCSAKVYIVLCGEH
GLSGPRELYCPEQPLFERNSRHTFVLSVPALLGPLRRICLWHDSRGPAPAWYVSHIMVKE
LAAGPGHSWLFPAECWLAASGRDGHTAWELGSLRRGLGFWKLLYCKFTEYLEDFHVWTSV
YSRPSPSGFLPTARLTVAFALLCAYACLTALVTAAGQEQLAWALSAPDAASAGSLWTGLL
GTLLASPGAQLLSLLFRLSQDAGGPSRVNACQSRSPLVGAAPKAAPEGPWARVGRATHPP
AEGSLVSGSSGACRRAARGDGAGCPPPEREDLGADAAQRARREKGSPGAQAASSGFGGVA
ALRWPWALLPWSGSAAWVLCGTVSVACGLGTAFLGYRFNPTQCVRWLYLLAASVLCCVLV
TQPLLVSLLALGFAWRRRHDPHFFTEALHAATKDLGPELEARARPHPPHCASQKEEVLAA
RQRVRHLRRARPPSAAQLSAVRQKLRRQTRTRRALRDMCMFTLLLLLHLLILCRTGSRDA
HSLHHAIRTEFTRGASSASGGLGSVADWWSWTLTTLLDGLHGGGAPPARPPGTQPRALGG
TCYLLGSLVIRQLRWPSGSAGQLPSRAPALPEDPPPEVGGPDGAPVTEPATPGDSRGCGS
REPWELSLGSTRPAAHAALSGLRAGGWIDGGTSAVSVHFVLYNCPTRLLSSVALHAELLP
AGGLALAPLVESVAAFHSDSGLWHRLALPEQLAFLVLSLTQSCLQLHRAAQEGVHSYWGE
PGSWLELAIAGAGLARYAASCHLATVAGAVTDRLHRGHFRGSMDLSLAASWSQRVMWLQG
TLSFLLTLKCVHLVSIRGTTASCSFLMRRSLASAFAAALAGVLALAAHSHLRAVPPGTLT
DFSRGPRSRLSRSNLQAPAWCCGALFMVMSTAWLGMLRGSFTTLAQRRKSFQSQSVVRLA
DVTAYVRTEALAWLGLERPQQEEAEMVESHNYYLDDVSDLLDELLSKIHALSDSLQLPLP
EQQFCDMREARAK

>Felis catus_PKD1L1(ENSFCAP_9861)
FLSPHSSLSHDGSVSWPCPKQLCPLAQCLPGAISVQGPADAVDPAVRCFPEADTRAPPSL
GFRVQVASEASLCLLLDFGDGCGVQVRIRNVSEGTAVTAFHQFGKEGVYTLKAVIHSEFR
GTEKELGPYYVDIGPATVSVSMNSSSIHKDGLLVLTDSHTDQKGTVVTHRFPTGPSWNVS
FTSRTRAGGGRAWKPVTVRFQMQPVSVYTNGTVFATDTDITFLAVTKETVPLEFLWYFGE
GPPVRTTSRSVRKRLRIPQWYSVTVQASSRLGRVASEPHRIRAQRRIIANRLASPSSALL
NTSVTFECRLNFGSDVAFLWDFGDGAVGPGGSSASHSYSREGEFTVQVLAFNDVSTASLR
KQLFVVREPCQPPPVKNMGLGKVQVWRSQPVNLGVTFESAILCDISQGLSYTWTFWNSEG
ARVPLPPAISTHRQTLTIPGYFLQPGNYTALAKVQVEGSVVHSSYRVGVEVRARAPVSVI
SEGTHLFISRAPSFIIVLRGSQSYDPDSPGAVLRYHWKCTAASAPGHPCFSASSPHSLDA
GAPTLSFPADSLSDTYDQFLVTLTVSSSGRNSSEAQVFLSPRPNSALRFVHISWVNFRDI
FVNWNEELCLQAECEVCGQVSGLSYSWDLFLVNATEGTSVEVPFCRTVGLLGSAGLGAIS
RPPESSPPSTEPSWPECHTTGAPFSQEPPQTRGQPGLSAAGKPSSGPTVSRHWVPATGDA
AAPGVTPQDQGSPGPSSPGGSSPSQGLSPSPSVFSSRVDFEVYYGNIQEAELSRGRQPAD
WPNPSLPGSDPSSSADRARGDGDNLLGPLPPTAAAGPPLMVDWPKSPVGRTLFHSYTASG
ITGQTVTIKPFALSPGKTYVLQASVASKHNFLGRAQLYVTLRPAPWAMTCQVQPHRGLEA
HTIFSIFCMSGRPDFHYKFSYRIGNGSRHTLYRGTDTQYYFALPAGEPLDDYKVMLSTEI
TDGSGSRAQPCAVAVTVLPRLHGGLCLDEDIYNSSLKHLSTLQLMGSYAEIRNYITMIAR
ILSRWAAEDRSPPCGQWSRIQDALISSACRLPSADQEEMLDSVLLFRDLLRFPHKVSFTS
AALVLKSTQALLAQSLLSGRPAVAEGTMLELILLVSAIWEVSDQETPRNVGFLQEEGIKV
ISALLLVTKEHQLCISAGQMEFCTLLHHDRQGTMQSLGPVRVHLPGGLAGQRPAAAGMQS
PCYISQLMLFKKNPYPGRRAPGQIGPLVALSLFTCSGRRPISRQRLREPVVVEFGEEDGL
GERRNRMTFALLREAVNFHRFTGRSESPQESLQIRIEFSRPVSRAFPVMVLVRFSEKPTP
SDFLVKKVYVWDEPMVHVYVPAASLRDTSLGYLSLLDADYDRMPRNKYFAKAVNYTVRFQ
WLRCVFWETREWRSANSSPQPGASPGKVSCSYDRLAPVSVARRNLSASFSVEGVSKLQRH
PGNLLPSILIAVSVVLYALLVTNTRRVDRHEREKAGYISLQEDTPADHQLYAVVVDTGFR
APAHCSAKVYIVLCGENGVSEPRELYCSEKPLFERNSRHTFVLSTPALLGPLRRIRLWHD
SRGPCPAWYVSHLMVQELGTGPAQHWLFPAECWLAAGRGDGHVQRELGCLRRGPGFWKLL
YSKFTEYLEDFHVWTSVYSRPSPSGFLRTPRLTVAFTLLCAYACLAALVTASRQERLLWA
LGAPDTAAGSFQTGLLCTLLASPAAQLLSLLLRLSQEPSGPRRVKPRLPPRRAPMGAAQG
RDQPGRPDSRRSSNSPLLPLLFLNTHSENYKTETVVPACSRPLCRPRCSTRKCKSNNTVH
MCIPTSGSGRLAVLQWPRAPPPWSGFAAWATCWMVSVACGLGTAFLGYRFNPTQCAQWLH
LLTLSVLCCVFVTQPLLVGLVALGFAWRKRDDPHFFTESLREATKDLGSELEGRVRSPMA
HRASQMEEMVAARQRARRLRWARPPSAAQLSVTRERMRRETRTRVALRDVCMHTLMLLLH
WFVLCGKVSQDEYSLHQAIRNEFTRNARSSSGGLTSVGAWWDWSLTTLLDGLHGQGAHTA
GVPHAQPGALGGKCYLMGALVIKQLRASSDSECELPSPPSVLTEDSPPTRSPQVGATDTS
SVTDPAIQGVAASGPGDYGAREHWVLSLGSTRAAAHAALSGLRASRWIDRSTRAVSVHFT
LYNPPTRLLSSVSLRAELLPAGGLALSPLVESVAIFHSNSSQWYRLTLPELVFLALNLIG
LCLHLSGMAETGVRSYWHSPGLWLELTVVGAGLAYHAASSHLVTLTGEVADHFQKGLFHE
FLDLSLVTSWNQRVSWLQGTLSFVLTLKCICLVGVQTPVASCSFLTRRSFAGVFAAGVFS
PQLAGVLMLAAHSHLSTAPPGTFTDVSRGLLFRFPGRRQRDTFPGLSKSDPRAPAWCCGA
FFIVTSTVWLGTLRGSLMTLVRKRKSFQSKSLVSLEDVTACVWGQCLALLGLERPQGEEA
ETVESQHYYLDEVSDLLEELLLKINGLSDSLRLPRPEQQSCDETEARAEGGPLGSISA

>Monodelphis domestica_PKD1L1(ENSMODP_33311)
MGNFGEIRNYITMLTSILNDFYTEDQSSTLSLQSQMRNLLISSVCTLSFQDQEEMADSIL
MLNELISISKQVTFSSTVLIIKYVRKLIDHSNLSGQFVMNKELMSNVIFLVSRALEVKEK
EKSRNAKYFREGIRNIVFLLLNYVSSGKEFQFNISTGQMAFQTNLHYTFHNSVEHVGSVK
VHLPDDLDEYISKGMGLHGQCYISQLIYFKEYPYLEEIVPVQTGGVMVALSLYNCTSKRK
ISIKRLTSPVTVAFEKSDAQDDEQNKTIFSLFRDKVNLHYFSGLPETSQESLQIVVEFSK
TILRTFPIMLLVRFSEKPTISTFNVKQIHSWDEQVVQIYIPAVSLKDAASGYLSLLDADY
DQKPTNKYLADIVNYTVSFHWIRCLFWDEDREWKSDDSYPQQGTSPQTVNCSYNHFTTFT
VVRRKLKANFEINDVSLLRSIPQNLFPSILVLLSLLLFAFLAIASKRRDLHEQKKNGSIF
LQGNSQARDKQVYLVIIDTGFRAPAQLTAKVHIVFYGEYEFSETRELYCPEKPLFERNSR
HTFIVSIPNNLGPLWKIHLWHDNSGCSPRWYISHVIVKDLITGASWFFPAECWLAVNKWD
GKVDRELTPLKSGLGFRKLLYSKFTEYLEDFHMWISVYSCPSYSCFTHTERLTVCLFLVL
GYMSLNAALIAMQQEEYFPEVGLLDVSVVSLMNGMLSIFIISPVALLLSLLFRLSEKKEE
NSAAFVRYSRHFGDYSIDLDIPKGSHAHSKCPSGHIHSSGQLKICIHLPCRALKNQIVIC
CNDFPTQLSQRKMCLNQNHLSENNSNSKYDGLEEPTPRKLMVLPPWLSYVAWATCGLISI
ACGLMAGLLGYRFGPSKCIQWIHSVFFSIVGCIFVAQPLMIFFVALALAWRKRDHKGFFI
EALYDATKNLEYELHHLSKNHALYSSYCSTPNTAADFEKILVARQRARYLQWVHPPTLAQ
LKEARWRIRKEMLLQTAIRNFLTHILMLFLLIFIIFGKISHHEYYLNRAIQNEFTRNARN
PFIDIKNADDWWNWSLTTLLDGLYWDKENNDDIPRIQSGPLGGKCHLIGPSIIRQIKFTE
QFSIPVEASSLSHQPQNQDYENILQSESEKPKVIQTKRCLSCGQVENEEDEVSVVNLGRI
RAKAYSILINLRNSGWIDKRTREIATHFVLYNPPTNLFTSVSLLAEVLPTGDIITSSLVE
SFSIYHFHSALSYCILFSELVFLVLSLIHLCFQIFIMIQKGILSYWQNSRNWLEMCIIGM
SLSYFAHSIFHFILVVDVIDQFHRGFFQVFVDFDPILSWHQRNRYLQGSLLFLLLIKCLH
LLGIYKAIAPSLTMMRLSFSNIILPLLAGVLFTVVYSYLGRFLFSTHAFPFRSFADSFQM
LLLCFLGTNEKGTFFSLYKSNQYTTVYYYGTLFIAVIILWSGILKGVLIAFRQDAKRSCR
SQPLVRFKEVADHIWEKVLSSLGIQRPLLAVAEIIEDSNFYLDEFENVLDELLLRVNSLY
YSLHCSPLEKSPRDQEEVDQKDKTLAYYLSSPSVESNR

>Takifugu rubripes_PKD1L1(ENSTRUP_13465)
TVKIYTAKQVYPTNAAVTFLALSEDKPDSVEFLWDFGDSTLTRTTSGTITNKYRKPGRYD
VVLVVLRGGTQIATDVFPLVIQRPVRLNRLQHQVSVLLNHTVMMNCWVSAGTDLSFLWSF
GDGFSRPGHSTEKHIFQMTGEFRVTVTVFNLVSSVSLSSHIFVVTQPCQPPPVKNMGPSK
LQVRRYEVIRVGVTYEREFDCGSGGLHYSWILLDSAGWVFPLPAIDTHRQTLTLPGYLLD
YDIYTAVAKVQIIDSVVYSNYSVRVQVIPSSPVASIQGGTNIFVSRNTVVSLDGQKSYDP
DFPLNPVSFQWTCEPISSISSSCFHTDIPISSPVLKFPAGVLKQPFDQFRFVLTVFSSER
SSSSEIFITLTPNVIRKASVLCSQCQGDRVNWDQSFTFSALCDGCDVAPEHIQLTWSLYL
VNASSKPLLEDPLCHTVDLSTLSAEASQYSAASSDSAVVSGFEKVFKTRVKSLKMPNDSL
LSKNERKKSSLPPRSGEEPFLGGFDPQDHLFMPPGHDQSGILDSDQYEHSNISGFPVDPG
SSADWDFSFPVSESGQLDGQPALDIHLMSAEEGHAGISAGRPTGTTNEVSGEDRELLGPE
DLVPDPEEHEDEGSNLVDSRPSVVFREPILLDLSRELVEAEVFDSYTYTGTSSSLLSLRP
FSLNHGSRYMLEVTARSHDSVLGRTQLFFQTNPVPDGMMCQVQPAKGLELFTHFSIFCAS
GKEDLTYKYSIRVADPAPRTLYQGTDYQYYFSLPSGDPLDDYKVTIYTEIRSSTYGTVTT
PCPVSVQVLPHFSREASSSHLDPDLELSESGLRNLSALLPLGNSAEIRNYISLLTAILNR
LSLEDGSNTRAQRRARNVLICTTCQLESEEQESMEDNINILRNLLQVTNQVTLVSARRVT
GHIQAISRRFSKFGTSVQFSLDQQTLNTLVALLSHSLQATEPLSAQHVVQLVTDVLEVTA
DLMLKYILLHEVQEHRVNSHLIVLHGRRQNQTAPVISGNLAALYLPDSLLLHLHVHHRGE
TESRPSQPCVLAILIEFSLSPFTWARHHERLNGPVVDLNLYQCSTRRKIPDFSLIEPVTI
ELQEQPREKNVWNSSQTSEHQHILQHRQVDYHSFNITQEHLQHAIQLRVHFRPPPNKVFP
IMLLFRMFERPTTSMHHLSRTHRWEGNTVILTLPTSVLSTAGVGYLALLNADFAKSARRK
DVSKQVRYSFRVDSSVCLSWDAQQGFWTHSSCRTMQTDATASVNCSCNQLRPTTVVQQEI
HSSYDTSDVNLLFSMPSNLTVLCVLLLCVCPYVPGWVACKRADAISEENQRVHHLSDNCP
HDQYLYAVTIHTGPCSAACMSAKVYIVLYGEDAVSQTKELQVPECTLFKRNSQDTFILSA
ADSLGPVWGVHIWHDNSGSSPSWYLKQVEVCEVSPGPVNKWLFVAQCWLAVDKDDGQVER
TLRVCEQGITFAELLRLKLHDYLADYHIWMSVLSCPHPNPFTHKQRLCVSLLLLLGYAAV
NIAVILKMEDQFDVAMIDVSALSVKTGVVSALLVLPAVLSLSFLFRLREIKLTHLEIHQT
NDSSEGEILQHFPQGKHRFPSLPFFLTDVLSTIDGSSQQSALKVGNEEGIKASHEKQKVY
VQQQSGLRPVSHWCHCLAWALSVLLCILCLVYAAILGNRLSGSQVLLWIHSLFFSLTSCI
FLIQPAVIMTAAVIVSLWYKERADFHSFSTKGQFELSNCPTNLQSNFSANGSSDLAKLLR
ARQRLRYLRLVCPPTLVELRKSRRERRRDAVLLKTIRDLFFCGSMLFLMLCILQNNSLTD
QHHLGNVIRKKFTSRGHDNTFMSIHTHEDWWKWAQSNLDLLYKDASAAPQVGCRVNILVL
KCLIKGDSAVNLLLKRLWTSLKLSRKLDVPGSTLMCAKTCIHPDCHIGTNATVSLGYKKS
DALSILKALHSSGWLNRCLTVKLRFTLFSPASNRFTSVTMLAEQRLTGVMQPSAEVHTAR
VYHTPALWDYVVMVLQLLYILFSLLQLCDQVHTLGQQGIMGYWKAPCNWMEVGLLTVTLV
YHIFCIYGSVLILEFRKLLQRQEGHVDVSLLATCEQHIRSLRGVMLFFLMLKSLIVLRVF
RTMATSAKLLASSLAKLF

>Tetraodon nigroviridis_PKD1L1(ENSTNIP_1786)
LHSVKIHTEKRAYPTNAEVTFLAVSKDQLHPLDFLWDFGDSSSTRTTSGRITKKYTKPGR
YDVVLVASRGGSRVAADVLSLVVQSAVRLNRLQHQASVLLNHTVTVNCRVSAGTEVSFLW
DFGDGSSRPGQSTEQHVFQMTGEFRVTVTVFNLVSSASLSSHIFVVTRPCRPPAVKNMGP
SNIQVRRHEVVRVGVTYEQEVDCGSGGLGYSWTLWDSAGGVFPLPGIHTHRQTLTLPSFL
LDYDTYTAVARVQVADSVVYSNYSVRVQVIPSPPVASVQGGTNIFMSRNAVASLDGRESY
DPDFPTNPLRFRWTCEPVSSLSSSCFRTDVPMSSPVLVIPAGGLKPNFDQFRFVLTVHSS
NRSASSEVFITLTSNVIGKASVLCSQCRGDRINWDQPFTVSASCEGCDLGPGHVEYSWSL
YLVDASSKPAPEGPLCQTADLRSPSAVVQAPVTSTFHPPSQSAAARSGVSGLDNDLKTTG
GRVWSKKDRKKSSVSPGSGTGTHRPLQAVIVQPGPGEQAFLGEFDPRARPFTAPGHDQSG
ILDPAQLDPSDDTSGFPLDPESSADWEFSFPASESDGLDGGPGEDQEPLGPGEESQPDLE
EPVDEGSNLVDSRPAVLIREPLLLDLPRELVEARLFDSYTYTGLSSPQLSFRAFSLEQGS
RYMLEVIARSAGVLGRTQLFLKTNPAPTGVTCQVRPAQGFELVTHFSIFCTSGKKDLTYK
YSLRVGDGPPRTLYRGTDYQYYFSLPSGDPSDDYRVTVSTEVRSSLDRTVSKACSSSVRV
LPSFSSLESGLRNLSALLRLGNGAEVRNSISLLGGALNRLSWDDGGSTRAQRRARNALIC
TVCQLESGDQESAEDSVGILGNLLRVTNQVTLMSVRRVSTHVQTMSQWFRESASSGRFGL
DPKTLEALVALLSRSLQASLTGRHFEQRTSSGADADGEEGADSGGSIGNGSFPVTSCEDE
TYMLFHGVREHRVHSDLMVVHAMRRNHTPAVVGGDSAAFYLPDSLFSLLPVQAQSGPGER
TQLDGPVVDLDLYQCGMRRKIPSRSLVVPVTVQLRPPPQPTHVGNSFLFSNLQRQVGYHG
FNVTQQHLRRAIQVTVHFRRPPNKAFPITLLFRMFERPTPSMHHLSRTHRWEGDAVVLTL
PPSFLSTAGVAYVALLDAEFAKASGRRHVSAHVSYSLRVDSRACLSWDAQRASWTPSGCR
TLQTDATAAVNCSCDRLRPTTVAQQQMGCSYDSADLDLFLSVPSNPTVLCVLLLCVCLYI
PAWVACRRADAIAKENRKIHHLSDNSPHDRHLYAVSVRTGPRSALRMSAKVYIVLYGEDG
VSQTKELQVPGCTLFRRNSQDTFILSSAERLGPVWGVRVWHDNSGSSPSWYLNQVEVCEV
GPGPVQERSWLFVAQRWLAVDKDDGRVERTLRARTPGRSFSEMLRLKLSDYLADYHIWMS
LLSCPHPNPFTHTQRVCVSLLLLLTHAAVNAAIVSQTDDPALFRAGVMDGSALSVKIGAV
GALLALPAAAAVSFVFRGRQIELTGSDARRRRGSSGGVVSAVDGPPHHHHSWIQLWPHES
REKKHPLTPVLERSRGGEEGNDSGAQRAPGSALKAEEDEEKEPGVKQMRRIQGRRGLLPP
SLWRGYLAWTLCVSLSSCCLVYSAALGNKCLCWRMSSGQVLLWIHSLFFSLTSCFFLLQP
ALITAAAVAVSLFGKGNYQESSGLRRSSTKDQLDLSDSSRPEAWSCFPTDGSSYLDKLLR
ARQRLRYLRLLRPPTPAQLRKSREERRRDALLLKTIKDLFFCGSTLFLMVCINLNGSFTD
QHRLRNAITKQFIGRGRDDTFLSVQTHEDWWTWVQSSLHLLYKNASVPPEVGCRNGGVQL
LQSVIVLQLVCVILVDFQAPGVTAVLERIHSSLSGSRTWAVPGSTKSSAETCAGPDCDVG
PNATVSLGCTKSDALSRLKSLRSGGWLDRRLSAVKLQFTLFSPAPNLFTSVTLLAVQRPT
GVLQPSAKVHTVRVYRTPALWDYVAMVLQLLNIVCSLLQLRDQVHALGQQGIMGYWRAPR
NWMDVALLTATLVYHLYYLYRSVLILEVVELLQERRGHVDVSLLATCEQHVRSLCGVTLF
LLLLKSAAALRVFRPTLTPAALLTRSLPQLLWPTISGVILMVALSSMGNLLFS

>Homo sapiens_PKD1L2(Q7Z442)
MSAVGLVLLVLALRLRATTVKPEEGSFCSNSQVAFRDACYEFVPLGRTFRDAQSWCEGQG
GHLVFIQDEGTQWFLQKHISQDREWWIGLTWNLARNGTTEGPGTWLDTSNVTYSNWHGGQ
AAAAPDTCGHIGRGPSSEWVTSDCAQTFAFMCEFRVGQSLACEGLNATVHCGLGQVIQVQ
DAVYGRQNPHFCTQDAGRPSDLEQGCSWANVKEEVAGQCQELQSCQVAADETYFGNLCPT
QGSYLWVQYQCREALQLMVSSESFIFDNVTISLTWLLSPYIGNLSCIISTGDSHTFDPYN
PPSVSSNVTHQFTSPGEFTVFAECTTSEWHVTAQRQVTVRDKMETLSVTACSGLSQSGAG
PLCQAVFGDPLWIQVELDGGTGVTYTVLLGDITLAESTTQKGSLPYNLILDRETQKLMGP
GRHRLEIQATGNTTTSTISRNITVHLVELLSGLQASWASDHLELGQDLLITISLAQGTPE
ELTFEVAGLNATFSHEQVSFGEPFGICRLAVPVEGTFLVTMLVRNAFSNLSLEIGNITIT
APSGLQEPSGMNAEGKSKDKGDMEVYIQPGPYVDPFTTVTLGWPDNDKELRFQWSCGSCW
ALWSSCVERQLLRTDQRELVVPASCLPPPDSAVTLRLAVLRGQELENRAEQCLYVSAPWE
LRPRVSCERNCRPVNASKDILLRVTMGEDSPVAMFSWYLDNTPTEQAEPLLDACRLRGFW
PRSLTLLQSNTSTLLLNSSFLQSRGEVIRIRATALTRHAYGEDTYVISTVPPREVPACTI
APEEGTVLTSFAIFCNASTALGPLEFCFCLESGSCLHCGPEPALPSVYLPLGEENNDFVL
TVVISATNRAGDTQQTQAMAKVALGDTCVEDVAFQAAVSEKIPTALQGEGGPEQLLQLAK
AVSSMLNQEHESQGSGQSLSIDVRQKVREHVLGSLSAVTTGLEDVQRVQELAEVLREVTC
RSKELTPSAQWEASLALQHASEALLTVSAKARPEDQRRQAATRDLFQAVGSVLEASLSNR
PEEPAEASSSQIATVLRLLRVMEHVQTTLLLGKLPGGLPAMLATPSISVYTNRIQPWSWQ
GSSLRPDAADSATFMLPAASSLSSLEGGQEPVDIKIMSFPKSPFPARSHFDVSGTVGGLR
VTSPSGQLIPVKNLSENIEILLPRHSQRHSQPTVLNLTSPEALWVNVTSGEATLGIQLHW
RPDIALTLSLGYGYHPNKSSYDAQTHLVPMVAPDELPTWILSPQDLRFGEGVYYLTVVPE
SDLEPAPGRDLTVGITTFLSHCVFWDEVQETWDDSGCQVGPRTSPYQTHCLCNHLTFFGS
TFLVMSNAINIHQTAELFATFEDNPVVVTTVGCLCVVYVLVVIWARRKDAQDQAKVKVTV
LEDNDPFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDTPVFERGAVD
AFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNSWLSINVGDC
VLDKVFPVATEQDRKQFSHLFFMKTSAGFQDGHIWYSIFSRCARSSFTRVQRVSCCFSLL
LCTMLTSIMFWGVPKDPAEQKMDLGKIEFTWQEVMIGLESSILMFPINLLIVQIFQNTRP
RVAKEQNTGKWDRGSPNLTPSPQPMEDGLLTPEAVTKDVSRIVSSLFKALKVPSPALGWD
SVNLMDINSLLALVEDVIYPQNTSGQVFWEEAKKREDPVTLTLGSSEMKEKSQCPKPKAA
RSGPWKDSAYRQCLYLQLEHVEQELRLVGPRGFSQPHSHAQALRQLQTLKGGLGVQPGTW
APAHASALQVSKPPQGLPWWCILVGWLLVAATSGVAAFFTMLYGLHYGRASSLRWLISMA
VSFVESMFVTQPLKVLGFAAFFALVLKRVDDEEDTVAPLPGHLLGPDPYALFRARRNSSR
DVYQPPLTAAIEKMKTTHLKEQKAFALIREILAYLGFLWMLLLVAYGQRDPSAYHLNRHL
QHSFTRGFSGVLGFREFFKWANTTLVSNLYGHPPGFITDGNSKLVGSAQIRQVRVQESSC
PLAQQPQAYLNGCRAPYSLDAEDMADYGEGWNATTLSEWQYQSQDQRQGYPIWGKLTVYR
GGGYVVPLGTDRQKHVKILRYLFDNTWLDALTRAVFVESTVYNANVNLFCIVTLTLETSA
LGTFFTHAALQSLRLYPFTDGWHPFVVAAELIYFLFLLYYMVVQGKRMSKETWGYFCSKW
NLLELAIILASWSALAVFVKRAVLAERDLQRCRNHREEGISFSETAAADAALGYIIAFLV
LLSTVKLWHLLRLNPKMNMITAALRRAWGDISGFMIVILTMLLAYSIASNLIFGWKLRSY
KTLFDAAETMVSLQLGIFNYEEVLDYSPVLGSFLIGSCIVFMTFVVLNLFISVILVAFSE
EQKYYQLSEEGEIVDLLLMKILSFLGIKSKREEPGSSREQPGSLSQTRHSRPAQALPKD

>Callithrix jacchus_PKD1L2(ENSCJAP_30637)
MSAVSLVLLVLALRFRATTAEPEEGNFCSKSQVAFRDACYEFVPLGRTFHDAQSWCEGQG
GHLVFIHDEGTQQFLQKHISQDREWWIGLTWNLAQNGTTEGLRTWLDTSHVTYSNWRRGQ
ATAAPDTCGHIGRGPSSEWVASDCTQTFAFVCEFGVGQSLACEGLNATMHCGSGQVIQVQ
DAIYGRQNPHFCTQDAGRPSDLGQGCSWANIKDEVAGQCQGLQACQVAADETYFGDLCPT
QGSYLWVQYQCREGLQLMVSGESFIFDNVTISLTWLLSPYIGNLSCIISTGDGHTFDPYY
PPSVSSNVIHQFTSPGEFTVFAECTTSEWHVTAQKQVTVRDKMERLSVTACPGLSKSGAS
PLCQAVFGDPLWIQVELDGGTGVTYTVLSGDVTLAESTTQRGSLPYNLTLDRETQKLMGP
GKHHLEIQATSNTATSALSRSVTVYLVELLSGLQASWASDHVELGQDLLINVSVAQGTPE
ETTFELAGLNATFSHKQVSSGEPFGIYHLAVPVEGTFLVTVLVRNAFSNLSLDVGTITIT
APSSLQEPSGMKAEGKNKEEGYTKVYIQPGPYVDPFAAVTLDWPDNDKDLRFQWSCGRCW
VQWSHCVERQLLRTDQKELVVPASCLPPPDSAVTLRLAVLRGQELENRAEQCLYVSAPRD
LRPQVSCERNCRPVNASEDILLRVTMGEDSPVAVFSWYLDNTPAEKAETLPDVCRLRGFW
PSSLTLLQSNTSTLRLNGSFLQTRGEVIRIRATALTSHAYGEDTYVISTLPPPEVPACTI
APDEGTVLTSFAIFCNTSTALGPLEFCFCLESGSCLHCGPEPVLPSVYLPLGKENNDSVL
TVVISATNRAGDTKQTQAVVKVALGDTCVEDVAFQATVSEKIPTALQGEGGPEQLLQLAK
ALSSVLNQEHEKPGLRQSLQLLLSPPKVREHVLGSLSAVTASLEDLRGVQELAEVLKEMT
RQSEELTPSAQWEASWALQRASEALLTASAKARPEDHRCQAATRDLFQAVGSVLEASLTN
RPEEPAEASGSQTATVQRLLGVVEHMQTSLLLGKLPGGLPAVLATRSISVYTNRIQPWSW
QGFSLHTAAADSASFTLPAASLLGSLEDGQEPVDIKMMSFPKSPFPARSHFDVSGTVGGL
RVTSPSGQLISVKNLSENIEILLPRHPQGYSKPTVLNLTNPEALWVNVTSGKAALGIQLH
WRPDITLTLSLGYGYHPNKSSYDAQTHLIPTGAPDELPTWILNPQDLHFREGVYYMTVFP
ESDLEAAPGRNLTVGITTFLSHCVFWDEVQETWDNSGCHVGPRTSPYQTHCLCNHLTFFG
STFLVMPNAIDIHQTAELFATFENNPVVVTTVGCLCVVYVLVVMWARRKDAQDQAKVKVT
VLEDNDPLAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGESEPHHLSDPNTPVFERGAV
DAFLLSTLFPLGELQSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNSWLSIDVGD
CVLDKVFPVATEQDRKQFSHLFLMKTSAGFQDGHIWYSIFSRCARSSFTCVQRVSCCFSL
LLCTMLTSIMFWGVPKDPAEQKMDLGKIEFTWQEVMIGLESSILMFPINLLIVQIFQNTR
PRVAKEHSSEKRDRGSPNPTPSPQPMEDGLLTPEAVTKDVSRIVNSLFKALKVPSTASGW
DSVNLRDINSLLALVEDVICPQNTSGQVFWEEAQKREDLVTLTLGSSQMKAEPDPCLNDA
RARSRWQDSASTRYLTLSLGVLAFTARRTGHRGEYSEPALCREFPKQLPTLGSGGMVTLT
MSVHLCSTFRASKPPQGLPWWCILVGWLLVAVTSGMAAFFTMLYGLQYGRASSIRWLISM
AVSFMESVFITQPLKVLGFAAFFALVLKRVEEEEVTVAPLPRHLLGPDPYALFRARRNSS
RDVYQPPLTAAIEKMKTTHLKEQKAFALIREILAYLGFLWMLLLVAYGQRDPSAYHLNRH
LEHSFTRGFSGVLGFREFFEWANTTLLSNLYGHPPGFITDGNSKLVGNAQIRQVRVRESS
CPLAQQFQASLNGCRAPYSLDAEDLADYGEGWNASTLSNAWQYQSQSQRRGYPIWGKLTV
YRGGGYVVPFGADRQSTSRILRYLFDNTWLDALTRAVFVEFTVYNANVNLFCIITLTLET
SALGTFFVHAAFQSLRLYPFTDGWHPFVLAAEVIYFLFLLYYMVVQGKRMRKQTWAYFCS
KWNLLELAIILASWSALAVFVKRAVLAERDLQRCRNRREEGISFSETAAADAALGYIIAF
LVLLSTVKLWHLLRLNPKMNMITAALRRAWGDISGFIIVILTMLLAYSIASNLIFGWKLR
SYKTLFDAAETMISLQMGIFNYEEVLDYSPVLGSFLIGSCIVFMTFVVLNLFISVILVAF
SEEQKCYQLSEEGEIVDLLLMKILSFLGIKCKTEESGSSREQPGSLSQTRSSQPAQALPK
V

>Mus musculus_PKD1L2(ENSMUSP_104721)
MAGLVFLGLALSSGATVAKSEGGSLCSRSQVFFRDACYEFVPLEHTFPGAQGWCEGHGGH
LAFIPDEDTQQFLQRHITQDREWWIGLTGGSGHNGTVGGSGTWLDTSNVNYSNWQEGQAT
PAPGSCGYIGSGPSSQWAALEDCTQTFAFVCEFGVGRSLACEGHNATMHCDSGEVILVQD
AFYGHQTPYLCTRGIWPPSDLEGECGWVSVKDEVAGQCQGLQACQVAVDGTYFGDPCPTR
GSYLWVQYQCLEGLRLVVPNGSFIFDNVTISLMWLLSPYTGNLSCVLSMGDGYTFDPYNP
PSVSSNVTHQFSSPGEFTVFAECTTSEWHVTAQKQVILCEKVETPRITGCTGLAGAGVGL
LCQAVFGEPLWVQVDLDGGAGATYAVLSHNRTLAEFTAQRGSQLYNLTLDRDIQEMLGPG
RHHLKIQAVSNEGTGTASAPSGNFTVYFVEPLSGLRASWASDRVELGWDLVVNVSVARGT
LEELTFEVAGLNANFSQEEESVGQSSGNYHVAVPAEGTFLVTVHVRNAFSELSLDIGNIT
VTASSSLQELSGINAEAKSGHKQDMKVFTEPELYVDPFTEVTLGWPDDDPGLNFHWSCGR
CWAQWNACVGRQLLHTDQRLLVLHTFCLPPLNSAVTLHLAILRGQELEKETEQCLYVSAP
LNLGPQISCEKNCRPVKADQDVLLTVTVGDETSVAVFSWYLDDTVPEEAEPLPAACRLRG
FWPRSLTLLHSNSSVLLLNSSFLQTWGPVIPIRVTALTSHAYGEDTYMISMLPRPEVPAC
TIDPEEGSVLTSFTVSCSTPATLGPVEYCFCLPSGFCLHCGPEPALPAVYLPLGEEKDGF
VLPVVISVTNRAGDIEQTQVAVKVGHSYTGVEDVTFQEMVSERIATALHQESGREQLLLF
AKAVSSELNSEVQSPGSGQLGMDIKRKVRELMLRSLSVVTTGLQNMQRVQALAEVLREVT
QRAEELTPAAQWEASCALQRATEALLVASTKVRPEDQRRQEATRAMFEAVGSVLEASLSH
RSEEPMEANSSQVAYIVAQLLRVIDHFQSALLLGTLPGGLPAILVTPSISVYTDRIQPRS
WQGSSVHTAAADSVTFTLPAATFLCPMEDSQEPVDIRMMSFSQNPFPSRSQFDVSGTVGG
LRLTSSSGHPIPVKNLSQNIEILLPRISAHIEPKMLSLASREALSVNVTAGDTALGIQLH
WGPGVPLILSLGYGYHPNETSYDAQTHLPPVAATGDLPTWILHPEDLPFGEGVYYLRVVP
EADLESSSGRNLTVGITTFLAHCVFWDETQETWDDSGCQVGPRTTPSQTHCLCNHLTFFG
SSFLVMPNAIDVRQTAELFATFEDNPVVVTTVGCLCMLYVLVLIWARRKDIQDQAKVKVV
VLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTLTLYGSDGESEPHHLSDPDAAVFERGGV
DVFLLSTLFPLGELQSLRLWHDNSGDRPSWYVSRVLVYDSVVDRKWYFLCNSWLSVDVGD
CVLDKVFPVATEQDRKQFSHLFFTKTSTGFQDGHIWYSVFCSATRSSFTRVQRVSCCFSM
LLCTMLTSIMFWGVPKDPAEQKMDLGKIEFTWQEVMIGLESSILMFPINLLIVQIFRNTR
PRLPMGKDGRQKQGPPNLTPSAQPTEEGLLTPETGIQSLISSLFKALKVQPPASGWDSMN
PVDINYLLTLMEDIICPESTEGPGFWEEAKGREDPITSTRGSVKPKENTWHPKPELAVRG
LWKDSVYRRCLYLQLEHVERELQLLGPQGFLHHHSHAQALRQLHVLKGHLWGQPGTPALA
YPSTSRVSKSPRGLPWWCVLVGWLLVATTSGVAAFFTMLYGLHYGRVSSLKWLISMAVSF
VESVFITQPLKVLGFAAFFALVLKREDDEETLPLFPGHLSSPGPGVLFRSRRHSSERAYQ
PPPMAAIEKMKTTRLKEQKAFALIREILAYLAFLWMLLLVAYGQRDPNAYHFHRHLERSF
SQGFSPVLGFRGFFEWANTTLVKNLYGHHPGFVTDGNSKLVGSAHIRQVRVRESSCAVAQ
QLQDSLDGCHGPYSLGIEDLVDYGEGWNASAYNNSNGFPQAWRYQSQSQRRGYPMWGKLT
LYGGGGYVVPLGTDHQSASRILQYLFDNSWLDALTRAVFVEFTVYNANVNLFCTVTLTLE
TSGLGTFFSHVTLQSLRLYPFTDGWHPFVVAAELTYFLFLFYYMVVQGKLMRKQKWGYFC
SKWNLLEVAIILASWSALVVFVKRTILADRDLQRYREHRDEGISFSETAAADAALGYIIA
FLVLLSTVKLWHLLRLNPKMNMITSALRRAWGDISGFVAVILIMLLAYSFASNLVFGWKL
RSYKTLFDAAETMVSLQLGIFNYEEVLDYSPILGSLLIGSCIVFMTFVVLNLFISVILVA
FSEEQKSDQLWEEGEIADLLLVKILSFLGIRCKREETWSSSEQPELPPQALAPQPAQALS
RV

>Canis familiaris_PKD1L2(ENSCAFP_29653)
MSAASLVLLGLALRFRATISKPEEGSFCSKSQVAFRDSCYEFVPFTQTFYGAQSWCEEQG
GHLVFIHDEDTQQFLQKHISQDREWWIGLVGNSAQNGTIGGPGIWLDTSNVSYSHWHGKQ
ASPVLNTCGYIRRDASFGWAASDNCTQLFAFICEFGVGQSLACDGLNATMHCGSGEVIQI
QDAIYGRQTPHYCTQSAARPLEEECSWTSVKDEVAGQCQGLQVCQVAADGTYFGDLCPTQ
GSYLWVQYQCQEGLQLMVSNESFIFDNVTISLTWLLSPYIGNLSCIISTGDGHTFDPYYP
PSSSSSVIHKFTAPGEFTVFAECTTTEWHVMAQKHVTIRDKMERLSVTGCSSLSMSGASP
LCRTVFGDPLWVQVVLDGDIGTGVTYTVLLGNTTLAEFTTPRGLLPYNLTLDRAAQQRMG
PGIHHLEIRATSNTTTAAPSRNITVYFMEPLSGLQASLGSDHLELGQDLLVNVSVAHGIP
EGLTFEVAGLNATFFHEEASLEGPLGIYHVAVPFEGTFLVTVMVRNAFSNLSLEVGSITV
TAPSSLQGSFRTKAKEKNREKGDVQVYVEPGQYVDPFTTVTLGWPDSGKDLRFQWSCGRC
WAQWSYCVERQLLRTDQRELVLLPSCLPPPNSAITLRLATWRRRQLENQEEQCLYVSAPL
ELRPRVSCEKNCRPANTSEDIVLRVTLGDDSPVAMFNWYLEDTSLEKAEPLPAACRFQGF
WPSALILIESNTSTLRLNSSFLQTWGQAIRIKATAVTRHAYGEDTYVISSLPPPEVPRCT
ITPEEGTILTGFTIFCNTSSALGPLEYCFCLESGSCLHCGPEPALSSVYLPLGKVNNDFM
LAVVISVSNLAGDKQQAHAVVKVGLGDICVENVAFQAAVLENVTVTLQGERDPERLFQLA
TAVSSILDLESQGQGCRQLLNMDVRQKVREHVLGSLSAVTTILGDMQKVQRLAQVLREVT
HHSEELTPKAQGIQWEATWALQHASEALLALCSKAHPEDQRRQAATKDLFQAVGSVLEAS
LREGPEKHAEAKGSQMASVPQLLRVVEHVQAALLLGTLPGGLPATLATPSISVYTNRIQP
RSWRGSSVHTKAASSATFTLPAASSLGSMEDSWEPVDIRVMSFPKSPFPARSHFDVSGTI
GGFCLTSPSGHLIPMRNLSENIEILLPRLLEGHSEPTVLNLTSPEALWVNLTSDRAALGI
QLHWRPAIPLILSLGYGYHPNKTSYDAKAHIPPMAATDGLSTWILNPEDLHFGEGVYYLT
VVPESDLELIPGRDLTVGITTFLSHCVFWDEVQGTWDNSGCQVGPRTTLSQTHCLCNHLT
FFGSTFLVMPNTIDVRQTAELFATFEDNPVVVTTVGCLCVAYILVVIWAKRKDAQDQAKV
RVTVLEDNDPFAQYHYLLTVYTGHRRGAATSSKVTVTLYGLDGESEPHHLSDPDIPVFER
GGVDVFLLSTLFPLGELKSLRLWHDNSGDRPSWYVSRVLVHDLARDRKWHFLCNSWLSID
VGDCVLDKVFPVATEQDRKQFSHLFFMKTSTGFQDGHIWYSIFSCSARSNFTRVQRVSCC
FSLLLCTMLTSIMFWGVPKDPAEQKMDLGKIEFTWQEVMIGLESSLLMFPINLLIVQIFR
NTHPRVTKEQKTGKWDRGPLNLASSLQPMEDGLLTLEVVTKDMWRLVSNLFKALKVPPPA
SGWDSATLTDINQLLVLMEDVICLQNMEGQEFWEEAKQREDPLILPLGSLQMKERMQCLM
PEVVPSDSLKDNAYKQCLYLQLEYMEQELQLVGPHGFPQGQNHTRALSQLQMLKGRLRGQ
LGTPPPAYTGFRMASKPPRGLPWWCVLVGWLLVAATSGVAAFFTMLYGLHYGRAGSLKWL
ISVAISFVESVFITQPLKVLGFAAFFALVLKRVEDEEEPVASLPGRLSSPDPTALFRARR
CSRKDIYQPPLTTDIEKMKTTHLKEQKAFAFIREILAYLGFLWMLLLVAYGQRDPSTYHF
NRHLEHSFTQGFSAVLSFKEFFMWANTTLVSNLYSHYPGFITDGNSKLVGSAQIRQVRVR
ENSCPLVPHLQASLDRCHAPYSLDIEDLSDYGEGWNASILNNSRGFSQAWQYQNQRQRRG
YPIWGKLTVYRGGGYVVPLGTDRKSTSRILQYLFDNTWLDSLTRAVFVEFTVYNANVNLF
CIITLTLETSALGTFFPHANLQSLRLYPFTDGWHPFVVAAEAIYLLFLLYYMIVQGKLMR
KQKWCYFHSKWNLLELTIILASWSALAMFAKRAILAERDIQHYRSHGEEGISFSETAAAD
AALGYIIAFLVLLSTVKLWHLLRLNPKMNMITSALRRAWGDISGFIIVILIMLLAYSIAS
NLIFGWKLRSYKTLFDAAETMISLQLGIFNYKEVLDYSPVLGSFLIGSCIIFMTFVVLNL
FISVILVAFNEEQKNDQLSEEGEIVDLLLMKILGFLAIKRKREEPGSSSEQP

>Felis catus_PKD1L2(ENSFCAP_23777)
AVGLLLLGLALIFRAAIAKPEDGSFCSKSRVAFKDSCYEFVPLSHTFYGAQSWCEGQGGH
LVFIRDEDTQKFLQKHISQDREWWIGLVGNLARNGTTEGLGTWLDTSNVSYSHWRGGQAS
PAPDACGYIGRDASFGWVASDNCTQPSAFICEFGVGQSLACDGLNATMHCGSGEVIQIQD
AFYGRQTPHYCIQDAARPSDLEEGCGWLSVKDEVAGQCQGLQVCQVAADGTYFGDPCPTQ
GSYLWVQYECQEGLQLMVSNESFTFDNVTISLAWLLSPYIGNLSCIISTGDGHTFDPYYP
PSLSSNVTHQFTVPGEFIVFAECTTSEWHVMAQKHVTIRDKMERLIVTGCSGLSTLGASP
LCRTVFGEPLWIQVVLDGGRGVTYTVLSGSTTLAEFTTPSGLLPYNLTLDRAAQQRMGPG
MHHLEIRATSNTTSVPSRNITVSFTEPLSGLRASWASDHLELGQDLLVNVSVARGAPERL
TFEVAGLNATFSHEEESLQGPFGIYPVAVPLEGTFLVTVTVRNAFSNLSLEIGSITVSAP
SSVREPSGTNAKRKNREKGDRQVYVEPGQYVDPFTTVTLGWPDRDKDLRFQWSCGRCWAQ
WSYCVERQLLRVDQGELVLPPSCLPPPSSAVTLRLATWRGRELENQEEQCLYVSAPLELR
PRVSCEENCRPGHPREDTVLRVTMGHGSPGAVFNWYLDDTSLEKAEPLPPACRLQGFWPR
DLILLQSNTSTLRLNSSFLQTWGQALRIRATAVTGHAYGEDTYVIGSVSPPEVPTCTITP
EEGTVLTSFAIFCDTSSALGPLEYCFCLESGSCLHCGSEPALQSVYLPLGKVNNDFMLTV
VIFVSNRAGDKQQAHALVKVGLGDTHVENVAFQAAVVENITTALRGERDPERLFQLARAV
ASVLDQECQGRGCRRLLNVDVRQKVREHMLGSLSAVTATLGDMQKVQGLAQVLREVTHCS
EELTPTAQREATWVLQDASEALLAASSKAHPEDQRRQAATKDLFQAVGSVLAASLRDGPE
NPTGAHGSQMATVPQLLDVVERVQAALLLGTLPGGLPATLAAPSISVYTNRIQPWNWRGS
SVHTAATHSATFTLPAASSLGSMEASQEPVDIRMMSFPTSPFPARSHFDVSGTVGGLCLT
SPSGHLIPVKNLSENIEILLPRLSKGHSEPTVLNLTSPEALRVNLTTDGAALGIQLHWRP
DIPLTLSLGYGYHPNETSYDAKVHLPPTAAADGLSTWILNPEDLHFGEGIYYLTVVPESD
LELTPTRDLTVGITTFLSHCVFWDEVQGTWDNSGCQVGPRTTPSQTHCLCNHLTFFGSTF
LVMPNAIDVRQTTELFATFEDNPVVVTTVGCLCVAYVLVVIWARRKDAQDQAKVKVTVLE
DNDPFAQYHYLVTVYTGNRRGAATSSKVTVTLYGLDGESEPHHLSDPDIPVFERGGVDVF
LLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVHDLATNRKWYFLCNSWLSIDVGDCVL
DKEFPVATEQDRKQFSHLFLMKTSTGFQDGHIWYSVFGCSARSNFTRVQRVSCCFSMLLC
TMLTSIMFWGVPKDPAEQKMDLGKIEFTWQEVMIGLESSLLMFPINLLIVQIFRNTRPRV
TKEQNAGKWDRGSPSLAPSLQSMEDGLLTLEVDMWRLVSSLFKALKVPAPASGWESVTLM
DINQLLALVEDVICVQNMVGQESWEEAKQREDSSTRTLGSVQEEGKVKPDPFPNVRGRAQ
DDNAYRRCLYLQLEHMEQELQLVGPRGLSQGQSHARALSQLQTLKGLLAGRLGTPPQAHT
SSPMASKPPRGLPWWCVLGGWLLVAATSGVAAFFTMLYGLHYGRASSLKWLISVAVSFVE
SVFVTQPLKVLGFAAFFALVLKKVEDEDEPVVSLPGHPSGPDPSALLRARRCSRKDIYQP
PLATDIEKMKTTHLKEQKAFAFIREILAYLGFLWMLLLVAYGQRDPSTYHFNRHLEHSFT
QGFSAVLGFQEFFTWANTTLVSNLYSHYPGFVTDGNSRLVGSAQIRQVRVRESSCSRAPQ
LQASRHGCRAPYSLDVEDLSDYGEGWNASALNNSSGLSRAWQYESQSQRRGYPFWGKLTM
YRGGGYVAPLGTDRRSTSRILQYLFDNTWLDSLTRAVFVEFTVYNANVNLFCIITLTLET
GALGTFFAHANLQSLRLYPFTDGWHPFVVAAEVIYLLFLLYYMIVQGKLMRKQRWRYFHS
KWNLLELTIILASWSALAMFVKRAILAERDIQRYRNHGKEGISFSETAAADAALGYIIAF
LVLLSTVKLWHLLRLNPKMNMITSALRRAWGDISGFIIIILIMLLAYSIASNLIFGWKLR
SYKTLFDAAETMISLQLGIFNYEEVLDYSPVLGSFLIGSCIIFMTFVVLNLFISVILVAF
NEEQKYDQLSEEGEIADLLLAKILGFLGIKCKREDPGSGRKQPELLSEVRPPCTCVSCTQ
A

>Bos taurus_PKD1L2(ENSBTAP_53273)
MSTLAVVLLGLALEFGAITAKPDDGSFCSKNQVAFRDACYEFVSLSRTFYGAQSWCERQG
GHLVFIRDEATQKFLQKHLSRDREWWIGLTGSSARNGTAEGPRIWMDTSCVSYSHWRRGQ
DASAPKACSYIGRDPSFRWVASDNCTQEFAFICEFGVGQSLACEGLNATLHCGSGEVIQI
QDAFYGRRTPHYCIQGAGHPSDLEEECSWVSAKDEVAGQCQGLQACQVAADGTYFGDLCP
GRGSYLWVQYLCREGLQLMVSNESFIFDNITISLTWLLSPYIGNLSCIINMGDGHIFDPY
YPPSLSSRVTHQFTAPGDFTVFAECSTSEWHVMAQKQVTIQDNTERLRVTGCSGLTTSGA
SPLCWAVFGDPLWIQVELDGGTGVTYTVLLGNTTLAEFTTQRGPLPYNLTLDRGVQRRTG
PGMHHLEIRATNDSTNSAPSRNITVRFVEALSGLQASWASDHLELGQDLLVNVSVAHGIP
ESLTFEVAGLDTTFSYEKENLRGSFGTYHVAVPLEGTFLVTVLVRDAFSNLSLEIGSITV
TAPSSLQEPPRTKVQRKNRDKGKVELYVEPGQYLDPFTTVTLGWPDRDKDLRFQWACGRC
WAQWSDCVERQLLRTDQRELVVPPSCLPPSNSAVTLRLTVWRGPELENLGEQCLYVSAPL
ELRPRVSCEENCGPVDASRDVMLRVTMGDRSAAAMFSWYLDDTPLEKAEPLPEACRLGGF
WPRSSILLQSNTSTLLLNSSFLRICGQAARIRVTAVTGCAYGEDTYVVSSLPPLEVPTCT
IAPEEGTILTSFAIFCNVSTALGPLEYCFCLESGSCLYCGPEPALPSVYLPLGKENDDFM
LTVVISVSNHVGGRQQTQAVVKVAPGHTCVEEEAFQAVVWDNVTAILQGGRGPERLFQLA
RAVSSILDQGPGSRQLPRVDTRRKVRERILGSLSVVNATMGDMQRLRGLAEVLKEVTQRS
EELTPLAQREAGWALQHASEGLLAVSAEAHPEDRRRQTATRDLLQAVGNVLEASLRHRSE
EPAQANGSQMATVSRLLEAAEHVQAALLLGRLPGGLPAMVTTPSISVYTNRIQPWSWRGS
SVHVAAASSATFTLPTAPSLGSMEDYREPVDIRMMSFPKSPFPAGGHFNVSGTVGGLSLT
SPSGQLIPVKNLSEYIEILLPRLSETHGEPTVLNLSRPEALRVNLTSGSAALGIQLHWRP
DAPLTLSLGYGYHPNETSYDAQAHLPPTAASDELSMWILSPEDLHFGEGVYYLTIILKSD
LEPAPGRDLTVGITTFLSHCVFWDGVQGTWDNSGCQVGPRTTLSQTHCLCNHLTFFGSTL
LVMPNAVDVRQTAELFATFADNPVVVTTVSCLCVAYLLVLIWARRKDAQDQAKVKVTALE
DNDPLAQYHYLVTIYTGHRRGAATSSKVTVTLYGLDGESEPHHLLDPDIPVFERGGVDVF
LLSTLFPLGELRSLRLWHDNSGDQPSWYVSRVLVHDLAMDRKWYFLCNSWLSIDVGDCVL
DKVFPVATEEDRKQFSHLFFMKTSTGFQDGHIWYSIFSSSAWSNFTRVQRVSCCFSLLLC
TMLTSIMFWGVPKDPAEQKMDLGQIEFTWQEVMIGLESSLLMFPINLLIVQIFRNTRPWV
AKEQNAGKWDGRRLSLAPSPQPTEDGLLTPEAVTKDLWRLVSSLFKALKVPPPLLGWDST
NSMNINQLLALMEDVICRQIKAGQVFSEEVSQTGAPLTLTLGSVQVKENMQRSRPKVGPS
DAWKNSAFRQCLYLQLEHLEQELLLLEPRCSSQGQNHTRALGQLQTLKGCLVAQAGTLPP
AHSSSLQASKLPRGLPWWCVLVGWLLVVVTSGVAAFFTMLYGLHYGRTSSLKWLISMAVS
FVESVFVTQPLKVLGFAAFFALVLKRVEDEEEPVVPLPGCLSSPDPSALFRARRNSRRDT
YQPPLASDIEKMKTMHLKEQKAFALIREILAYLGFLWMLLLVARSYAKSRPGPRWGDGDE
WLNVVGHELLLADSTWVHWRSSTCFSSPGFVTDGNAKLVGSAQIRQVRVQESSCLLAPQL
QAFLDRCHAPYSLDVEDLSDYGEGWNASVLNNSNDFSQAWRYQSQSQRRGYPLWGKLTVY
RGGGYVVSLGTDRQSASRTLQYLFDNTWLDSLTRAVFVEFTVYNANVNLFCIVTLTLETS
ALGTFFAHAHLQSLRLYPFTDGWHPFVVAAEIAYFLFLLYYMAVQGELLRKQKWCYFHSK
WNVLELAIILASWSALAVFVKRTVLVERDLQRYRKHREEGISFSETAAADAALGYILAFL
VLLSTVKLWHLFRLNPKMNMITSALRRAWGDISGFIVVILIMLLAYSIASNLIFGWKLRS
YKTLFDAAETMISLQLGIFNYEEVLDYSPLLGSFLIGSCIIFVTFVVLNLFISVILVAFN
EEQKYYQLSEEGEIVDLLLMKILSFLGIKCKRQEPGSSSEQPVVIGEGQHIRPTLTSD

>Gallus gallus_PKD1L2(ENSGALP_8713)
LGITVLISLAVYLAMEEATDEEGIPCSKHQLAFNHSCYEFVRLQRTFTSAQRWCERGGGH
LVFIENEETQEFLQKHIAEDQEWWIGLISDSLLNETTDGSMIWLDTSNVSYSNWYKDQPS
PFSSTCGYILKNAKYQWGVTENCSQEFDFICEFENGQSIACDNYNATVQCGSGEVIQIGE
SFYGRKTPHYCVLETPPQNDTEEDCSWISIKDEVAGQCHGLQACQVAADGTFFGDPCPAS
GSYLFIQYYCKEGLQLVVTDTCFIFENITITLNWLLSPYSGNLSCIISTGDGHTVDPYYP
LTLLSNVTHRYTSPGEFAVFVECSTSEWHVTAQKQVMVQDKMDELSITGCYSHHESGNSS
QCRTLYGELLWIQAELNGGSGVTYVVLANNMTLIESSAKEGIAPHNLTLDSAAQELLGPG
MHQLEIRVSSNTTASEISESIAVHLIEPVSGLWAVLASHTLQLGENLEINVSMSHGAPAK
MRFEVVGLNETHSHQEDCPQGEPQTYIIPMHSEGTFLVKVMAMNAFSNVSLDIGFINVLA
NSSHKEKDTSKTNTQMTKGHQRKNKIHIKPSRHVDPFTTITLGWPDNNDNSSFLWSCGAC
WPEWDECVQHQMILTSQQEVQIPPSCLPPPKSAVTVRVTVRSHGNEERQDEQCLYVTATT
VLLPYRCEANCKPVNASEEVVLSVSGQKDSQDMYYNWYLDNTFQNKSAPLPPACSLTGFR
QNSLNLLQSNTSTLIMNSSFLQMHGEAFQIKVTALTQRGYGEQTYLVSTVPPPQVPSCAV
SPKQGSVLTTFTVSCSTPCSVDSCQSSHSTQLNYCFYLNSNSLLHCGPDPELFPVYLPLG
EEEDNFILHVTITVSNSFGDTVHTNASVKVIQADTIDGNLTLQTIVSEKANTILRDGNNS
MSLFQLFKSVTSVLNHETQEENSNISLQTDTRKELRGLMLTTLSAVNVTSVQTALKMSEV
LKDITYRTEELSVSAQVEASNTLKDVSASLLTVNTEDSRDDQKLMDAASYLFNAVSNVLQ
ASIQNRAMNTTVPEAEQSLVSHQLLNTVENLQSALLFGKEPDDEPMVLTAHSATMYINRL
QTENMDGTSINISSSSSASFTLPTASSLGISGVDDETVDIRMVSFAMNPFFSSDTSFDIS
GTLGGLSLTGLDGLIIPVSNLKENIEIILPRHSAPQEDRIQLNLGNFSIFQVNITSENTS
IVIQLECEHDIPLILYLGYGYRPNETNYDMKSHLFYKKTTGGETNTWVLSPEELIFGEGP
YYFMVSQDMGMDSTVYDGLAIAVTCFASRCVFWDEQQGNWNSYGCQVGPKTNSRSTQCLC
NHLTFFGSSFFVIPNAVDVSRTAQLFGTFVDNPVVVTTVGCIFLIYVLVVIWARRKDIQD
DAKAKITVLEDNDPFAQYRYLVTVFTGHRRGAATTSKVTLTLYGLEGESEPHHLTDPDTP
VFERGGVDVFLLCTLFPLGELQSIRLWHDNSGDNPSWYVNRVLVHDLAWDQKWYFLCNSW
LAVDIGECVLDKVFPVATEQDMKQFSNLFFMKTSKGFQDGHIWYSVFSRSPRSSFTRAQR
VSCCFSLLLCTMLTSIMFWGVPKDPAEQKMDLGKIEFTWQEVMIGFESSLLMFPINLLIV
QIFRNTRPRPAMQGTEKKPGKNGRVSPGLPPPPQVTPAISLTPEAVIKDIRRIANSLFKA
LKAPSLTSVSDLEKSTNINTLLALVEDIICQQNRAGQEFYDESKKKDDPVTVTLGPMDIQ
EKTRSPTPEKGMCERLKHSDYNRCLYMQLQRVEMELELLGPHKFQMPQSYTQAVRQVQHM
KNLLQNQICSSASISFSGDGKKSSSKGLPWWFVFIAWFLVAATSGVSGFFTMLYGLHYGK
ENSIKWLISMAISFFESLFITQPLKVLGFAAFFALVLKKVEHEDEENTAIDGPLPAPGNS
NPLFGARRDSRSNIYQPPPAADVEKMKISCMKEQKAFALIREILAYLGFLWMLLLVAYGQ
RDPNSYYLNKHIESSFTEGFHDVYSYEDFFTWAKTTLVKNLYGSYKGFITDGNSKLVGSA
RIRQVRVKGDSCPISPILQRVIQECHAPYSLQTEDTSDYGEHWNTSVFDISSDLSSAWHY
QSQSKLRGQPVWGKLAIYGGGGYVIHLGTDPQNASRILQYLFNSVWLDTFTRAVFVEFTV
YNANVNLFCIVSLMFETNALGAFFTSAELQSVRLYPYTNTLHIFVVAAEVIYFLFIVYYM
MVQGKLMKALKWRYFHSKWNLLEMAIILISWSALSVFVKRTILGSRDISYYQEHKEDSVS
FNETARADAVLGYLIAFLVLLSTVKLWHLLRLNPKLNMITSTLRRAWGDISGFITVIAIM
FLAYSIATNLIFGWKLCSYKTLSDSAETMVSLQLGIFNYEEILDYNPILGSLLIGSCIVF
MTFVVLNLFISVILVAFSEEQKHYQPSEEEEIVDLMLMKLFGFFGIKCKQEEKTGCNNQP
KQPPDGSEPRRADMAAPP

>Taeniopygia guttata_PKD1L2(ENSTGUP_4686)
ADGGIPCSKYQQAFNYSCYEFVRLQQTFTGAQSWCERGGGHLVFIHNEETQEFLQKHIAE
DQEWWIGLISNSLLNETTDGSITWLDTSNIIYSNWYKDQPSPFSSTCGYILKNAQYQWGV
TENCSQEFDFICEFESGQSIACDNYNATVQCGSGEVIQIEESFYGRKTPHYCVSETPLQF
ERDEGCSWISVKDEVAGQCRGLQACQVAADGTFFGDPCPALGSYLSIQYHCKEGLQLVMT
DTCFVFENITVTLTWLLSPYSGNLSCTISTGDGHTIDPYYPLTLVSNLTYRYSSPGEFTV
FVECTTSEWHVLAQRQVTVQDQVDQLSITGCYSQYETGNSSRCRTLYGEVLWIQVQLSGG
NEVTYSMLAGNMTLSESSAKEGLVSHNLTLSSASQELIGPGMHQLEIRASRTTMASEISG
TIAVHLIEPVSGIQAAVASHTLQLGEDLEVNVSVSHGAPEKLMFEVIGSNQTQWHKADGP
RGEPRTYGVPLPREGTFLVKVVAMNDFSNMSLDLGFITVLANSSHIKGNCINLTVLKQHM
YDHKIYIKPSRHVDPFTTVTLGWPDNNNNSSFLWTCGACWPAWNECVKQQIILINQSEVQ
IPPSCLPPPKSAVTVRITIQNHGSEERRDEQCLYVTAKQELQLEIRCEANCKPVNVSDEV
VLSVSEQEDSQAIYYNWYLDNTFQNKSAALPLACGLTGFQQNSLNLLQSNSSVLRMSSSF
LQTQGDAFQIKVTGTTQRRYGERGFLVSTVPPPEAPDCAVSPGRGSALTAFRLSCSAPGG
PGGQLTYCFYVAPDSLLDCSPDPELFPVYLPLGEEENNFILHVTVIVSNNVGDTVQTNTS
VKVGPADMMDGNLTLQAVVSEKANSILKDGNNSMSLFQLYKSVTSVLNQQIQEESFNMSL
PTNTRKELRGLMLTTLSVVNVTSMQTALKMSEVLKEITYRSEELSVSAQVEASSTLKHVS
ASLLAVNTEHSRDGQELKEAASYLFNAVSSVLKASSWEHFSARDKTGNLDLVHSVSHQLL
STVENLQSALLFGKAPGDEPTVLTSPSATMYMHRLQTENMDSTSINISNSSSASFTLPPA
SSLNVSGVDGETMDIRATHFAMNPFFSSDSSFDISGTVGGLSLTGVDGLIIPVSNLKENI
EIMLPRLSAIQEDKILLNLGNYSTFQVNDTSENTSIVIHLESEHDIPLILYLGYGYHPNE
TNYDMKNRLFYKKTSGGEMNSWVLSPEELIFGEGTYYLMVLQDMGMDSTVYEGLTINATC
FASRCVFWDEQQGGWNSYGCHVGPKTNPSSTQCLCNHLTFFGSSFFVIPNAIDVSKTAQL
FGTFVENPVVVTTVGCIFLIYVLVVIWARRKDIQDDAKVKITVLEDNDPFAQYRYLVTVF
TGHRRGAATTSKVTLTLYGLDGESEPHHLNDPDTPVFERGGVDVFLLCTFFPLGELQSIR
LWHDNSGDSPSWYVNRVLVHDLAWDQKWYFLCNSWLAIDIGECVLDKVFPVATEKDMKQF
SNLFFMETSKGFQDGHIWYSVFSRSPRSSFTRAQRVSCCFSLLLCTMLTSIMFWGVPKDP
AEQKMDLGKIEFTWQEVMIGFESSLLMFPINLLIVQIFRNVRPRPAQQGREKKPGKNGRV
SPSLLPTPGATQAASLTPEADIRRIANSLFKALKTPSLTSALDLEKSANINTLLSLVEDV
ICQQNRAGQGFYDEIKKDGPTIVTLGAMDIQEKTRNLTPEKRICDQLKYNDYHRCLYLQL
QHVEMELELLGPHKFQMPQSYTQAVCQVQHMKNLLENQICSSASITDKNSSKSSSPRGLP
WWFVFIAWFLVAATSSVSGFFTMLYGLHYGKENSIKWLISMVISFLESLFITQPLKVLGF
AAFFALVLKKVEHEDEENTAIDGPLSAAGDSHPLFGVRRDSRSNIYRPPPAADVEKMKIS
YMKEQKAFALIREILAYLGFLWMLLLVAYGQRDPNSYYLNKHIEDSFTDGFHDVYSYQDF
FTWANTTLLKNLYGSYKGFITDGNSKLVGSARIRQVRVKGDTCPISPRLHHIVEECHAPY
SLQTEDTSVYGEHWNTSALDNSSDLSSAWQYQSQSKLRGHPSWGKLAIYSGGGYVVHLGT
DPKNASRILQYLFNNVWLDTFTRAVFVEFTVYNANVNLFCIISLMFESNALGAFFTSAEL
QSVRLYPYTNSLHIFVVAAEVIYFLFIVYYMIVQGKLLKSLRWRYFHSKWNLLEMAIILI
SWSALSVFVKRTVLGTRDISYYQEHKENSISFSETARADAVLGYLIAFLVLLSTVKLWHL
LRLNPKLNMITSTLRRAWGDISGFIIVIAIMFLAYSIAANLIFGWKLYSYKTLLDSAETM
VSLQLGIFNYEEVLDYNPILGSFLIGSCIIFMTFVVLNLFISVILVAFSEEQKHYQASEE
EEIVDLMLMKLFSFFGIKCKKEE

>Xenopus tropicalis_PKD1L2(ENSXETP_61158)
CSLIRMWLWVAALCFLAPYSHADPSPCSKYQVLFNSSCYEFVRLERNFHSAQKWCERGGG
HLTFIDNQETQEFLGTYLSEDREWWIGLIYTPVNDSGQGFMTWLDASNLTFSYWHNGDPP
ETEKKCGYLRRQSGYHWSTTDNCRQELFFICQFEFGHTISCENQNATLQCGSGEVVQISD
SYYGRRSPHFCTQEEHSQITSGCSWTNVKDLVAAQCQGLQACQITTDSSLFGTPCPTSGS
YLSIDYNCIEGLQIELPDKCLVGENMTLTVNWLLSPYTGNLSCIISIEDGYSIDPYQPIN
VSSTVTHSFTLPGEFAVFVECSTSEWHVTAQKTITVEEHRAVLNITGCYSKFGSKNGVCS
TYYGETLWIQVEISTGGEVNYTLLSNNIILSQFRAKTEDLTYNLTLDRVAQNLMGPGLHR
LMIMASSNEIPFITPGNITVHLIEPVSGLLAELCNFVLEVGTELKINLSIAYGAPVNLMF
NIIDVNKTFSYTRENSSGEQQIYTIPVEAEGTYMVTVVAFNSFSNFSKNLGNITVLNIYD
TGLQDTEGKNENVTVIVKRTQAFRIEPSRYVNPFTSIVLHWPDSVGSNISWTCGSCWPGW
FECVEQNLIDPLSENILIPANCLPPPNTAFTVLATDRASEKEILQDEQCLYVTAKSTLPI
KISCKANCKEISLDEDMVFSATCDNKATFSWYLDTNFPKMTLSPPDACQHRDFRQSSLVL
LQKNTSTLVLNSTFLKTQTNTAFRIKLIAMNSQEYGEDTLVVSTVPPPEVPRCTIHPEEG
SVLSTFQISCRAPCASHLCDCCFWWISDSQLYCGPDSELPSIFLPMGEKENDFILNLTVT
VSNMYGTSVNTTLKVKVRQDEINTNSQTLVSLVSEKSANILKGDGVGSSLIQLYKSVSSV
LNQKIPEDSDSNPLQTEEKKELREVMLTALSAVNITSLHTALEMSEVLNDLTTRNEELSA
SAQVEASSALKGISESLLTVRSEPEETRKEAVQHLFNAVSNVLEATALDSSRMAPDMAAQ
SAVSLHLLGAVENLQSALLMGKLPDNEPTILTAPSASMYINRMKPGHLQGTSVNIKDPST
AAFTLPSLSSLSIPIGNEDAVDLRMVSFLVNPFSSSNTFDISGSVGGLSLTSPDGSVIPV
KDLTEHIEIILPRFSELEDEKSILSLVNFTSLLINVTSSVNSLVVHLEPSEEIPLVLYLG
YEYQPNETNYDITTHLPSKMYNRENIYSWVIGPEELLFGEGTYYLIVRSELEDLTPNDNL
TIVVTCFSTQCMFWDEANQDWNSTGCHVGPKTTPSSTQCLCNHLTFFGSSFIVMPNAVDV
SRTVELFATFVDNPVVVTTVGCIALVYVLVMIWARRKDIQDNAKVKIIALEDNDPFAQYR
YLVTVFTGHRRGAATTSKVTITLYGSDGESDPHHLSDPEGPVFERGGEDIFLLTTLFPLG
DVQTIRLWHDNSGDKPSWYVNRVLVHDMELDQKWYFLCNSWLSIEVGDCVLDKVFSVATE
EDMKQFSNLFFMKTSKGFRDGHIWYSVFSRSPRSSFTRVQRVSCCFSLLLCTMLTSIMFW
GVPTDPAEQKMDMGKIEFTWQEVMIGFESSLLMFPINLLIVQIFRNIRPKPAKKPAEKKE
RTFMSETIKKSPSSQEITSASLTPEAVMKDIRRIASSLSKTQKIPLPDVDLRKSTDINKL
LSLVEDIIRQQNRAGQEFYDESKKERSLILSLGSVDWQEELRSPTPEKSLREKPRFSDQN
RYLYLQLQHVEKKLEFLGPYQFQNPQCYSRAVSQVQHMKGILENQDGQATPTESSHKDGK
KNTRGLPWWFVFIGWLLVAATSGVSAFFTMLYGLHYGKDSSIKWLISMAISFFESLFITQ
PLKVLGFAAFFALVLKKVEPEDEEETTINGNLSTPGDPNPLLGSRRDSNIYQPPPPTDIT
KMKNNYMKEQKVFALIREILAYLGFLWMLLLVAYGQRDPNSYYLNKHIESSFTDGFEDLC
SYQEFFTWANTTLINNLYGSHPGFITDGNSKLVGGARMRQIRIKKDSCPVASVLQSTIDN
CRAPYSLDAEEMGHYDGSWNFSAITNATDVNSPWYYQNHSKLRGHPTWGKLATYRGGGYV
ADLGNERKYAHRVLQDLFSNIWLDSYTRAVFVEFTVYNANVNLFCIVKLMFETNALGTFF
TRANLQSVRLYPFTDGLHIFVVAAEVIYFLFVIYYMVVQGKRMKAEKWGYFRSKWNLLEL
ALIIISWSALSVYVKRTILGTRDLRYYQEHKNEFVSFNETAAADAALGYLIAFLVLLSTI
KLWHLLRLNPKLNMITATLRRAWGDISGFITVIVIMFLAYSIACNLIFGWKLNSYKTVFD
SAKTMVSLQLGIFNYEEVLDYNPVLGSFLVGSCIIFMTFVVLNLFISVILVAFSEEQKHH
QASDEEEIVELLLWKICSFLGLRHKKEE

>Danio rerio_PKD1L2(ENSDARP_104693)
MAFSKQLLIYCWISFVLMPLTTCTDESEDNEHQKYDYGRKVQQIRGGKMYKFVQESMSWI
EAQQSCEKHRGYLLRDLNDEIKELVLAQSTQTGPWWVSQTLMYKNSITGFELASFYPYKK
DGSAENHLACAYLVKDPFQLLTTPNCSMSFSSICTQDLNAHQKSSEETRRKRRGVTDILS
ALHGNVGTDQLLTDAKTMLKDLETTPIELTMDDRVSYLQAIYKNLKASTPNDNQLSEIVN
CTAAMLLYSQECEPDNMEEFEQLITLAGKIYAMAVVGNGNIVKDLPTGTIYVSRQNSSTL
GRKNIGSTDGGYCQLPSFSAMKSQLPSGNVNVQLFQFKVNPLEMKSDENITGTVCSFSLQ
SSNSSVKFKDLPENIEIYLPQPEAAQPEVVDVTWKNGFAVTSTFNITDANVTVVVTAVPN
RNISLSFTLHPPNGTNISSWNQSTTVTYKDGYRWLINPDMRKELDGTWKVSVLPTSYTSS
DVLTFKMSVFVTKCLFWDTDNGQWSREGCMVGPNTMPNLTHCLCNHTTFFGSSFFVMPNQ
VDLSKTAALFATVNENYIVVVVLSCFFALYLILVMWAWYADRKALRTRKMTLLEDNHPCA
QYNYLVNVQTGHRRKAGTTAKIKVMLQFAEGQSDSYSLSDSEKPVFERGGVDVFLLSMPF
SLGELQSIDISHDNSGGSPDWYLDKVMIQDLQTQDVSHFLCSTWLRGETCKRTFNSAKKN
EIASFGNIFQTRTSSGFRDEHIWVSIVDPPRRSPFTRVQRVSCCMSLLLCTMAINIMFWN
LPTDAESPVILKIGSFQLTWQQFMVAVESGLFMFPINILIITIFRHIKPRILLNKGKTDS
SKKTTPAASVSMNTIIQETVGLLNYLSKSPKNNLPAKEIQPETSGDLFWALDKVNHVLEI
MQAESIGDPHWFYCSHFVLYSLSHINNLLEHVGEKGCFLNEELRQARGIVNALLKKAEIV
SQKHTSQSQPVVQVQKKKQGWWLPWWFLFIGWFLLFVMSGISTFFTLLYGFQYGRESSIQ
WVVTLSLSLVQSIFIMQPLKVIFVAIFFAMILRPVAVENNEEVELLLQEQKEKCEEYSGK
SLC

>Takifugu rubripes_PKD1L2(ENSTRUP_44908)
LFVVGFILTYLNTYLGACHADDDAHAFSCPEHQEGFDASCYEFVSKQQSFLNAQGWCERG
GGHLAFILNDEIQQFLLKHLEPGLDWWLGLAPAAPNLTLDTTATDGSLAWLDGSDISYSN
WVNPPDTEAACGHILKHSGFQWEATANCSQELNFICQFESERSLACNDHNATLQCGSGQV
IEIDDSFYGRKTIHYCRSELTTSPASSQEECSWIDVTESITARCHGQQSCQASVNLSSLG
QPCPMLGSYLSIEYHCKNGLQLLLTKLAAVFDNVTITVRWLLQPFEGNLTCTLNAGDGHT
IDPYSPVKMESTMMHKFSHPGVFTVSVECTTSDWRVTAEKTITVQEPVRQFGVIRCYSRN
MSTDGNKCNVFHDGPVHVQVQVEQGTNISYGILLDDQLLANSSVDRGTTPYNITLSVNVM
EKLGLGCHNLTLTASNRITGHSVSSGLELCVQEPVKGLQASIVTDGDDCPDSTDLVISVS
LEKGAPVELLFSLTGATDALSEPRDMFNSSSKIYTFSSPLEDKGLLKVNVRAMNALSAFD
VDVDLSKILHACQNYSDHSLDESGNSTIGNMSINNVKIIAAPDTLMDNSQSVSLNVTGPD
LSPENGLTFEWKCRGNCKCGHKTKGDTHTIEKDCLPDPFDMIKYVVAVRRATWFRKPLKL
GSSSKCISVVPKKFTDVTISCEDCASISVNDHVKLKLNCVSTCPDVVWSIEDLKLDGLQK
CYLKAGRKPLVDKQEGNTEYVVRSQQLKLSKETFRNISVVVYAIPDAEPTKPSATGAPAD
PSPPSCSISPSSGTVLDAFDITCSASAFCSTGCSYCFKTDTGNHLRCSTAAEVRSVYLPL
GDMNNNYSLTVVVTVKNERGTTTSTVPTQVLMKVWKSSSSVEALQTTLEDTVSQLEQQGL
LTGEALGQIFTSVSDMLNTEANQDQLDARMELREQMLTKISTVLLDSPSNTTNQVEVTAR
AVAGLTQRPDELSLAAQEEAGSLLVDLSSALNTLTINQDDGGEVVHAATPIVEAASNILN
VSSSVSSSGKSRRCNILPQKKVSDFLLTGIDNVQSALLINKELNGEPAIIDSGQISVYVN
RLSPENMQMQTINVQKNTSSKFSFPPLPTHIVSPEEPVDVRMMSFETNPYSWKEGNITGT
VGSVSLTRMNGTTIPVRNLPEEIEILLPRLDIGRENNTVLDLANFSTVIIEVPSPDVTLV
LKLEPSDEISFMLFLGYKDYPSDENYVAKTRIPLKNSTAEEKYTWVLSPNDRTEDVGLHY
LVVKPIVEPGTKSVNATVTVISIAAQCKYWNETQSSWSEDGCRQVGPLTTPLVTQCLCNH
LTVFGSSFFVMPNLVDVSRTAELFATFTNNPVVVCFVGAIFAIYLLVVVWARRKDIQDSA
KVKITLLEDNDPLAEYRYLLVFNTGHRRGAATSSQVTITLLGSEGESEPHHLTDPEKPVF
ERGGVDMFVLTTHFSLGELQSIRLWHDNSGEHPAWYVNKVIVQDLESDRKWHFLCNSWLA
VDVGECSIDKVFPVATETDLKRFSNLFFMKTAKDFQDGHIWFSVINRPPCSTFTRVQRVS
CCFSLLLCTMLTSIMFWGIPTDPSEQTMDLGHIEFTWQQVMIGVQSSIIMFPINLLIVSI
FRNTRPREKASKTDASNQGKKGRVSPSKPSPKKESKDITPDTVMKDIKRIAQSLLKAMKS
PVPDMELRPGQQVDINTLLSLLEDIIRLQKWAAGDFYTDEIKKDHSKTLSLHSVNLQDNS
LYGSPEKTSEENPKRSGNSRYLYRQLHRVEKELGLLGPSGFPYPDRYNRAVQQVQGIKGL
LEYDLASSSLETAKKCCQRGLPWWFVFVGWTLVIATSGVSGYFTMMYGLTYGKDRSISWL
ISMLVSFFESLFITQPLKVLGFAAFFALVLKKVDQEEFGEPQINESLRYADPDMMCAVRR
DSTCSFYQPPPPTDIERMRNNMIKEQKVFALIREILAYAGFMWMLLLVAYGQRDPNAFFL
TQHIRQSFSKDISDSMSIQDVFNWANATLLSNLFGEYPGFITDGNSKLVGNARLRQVRVN
KDSCHTASSMQQPGRDCHAQYSWDLENMGSYSPGWSSVVVDNTSQNLDSPWVYQSQGRLR
AYPIWGNMMLYRGGGFVVDLGPDSQNSSRVLQYLYDNTWIDVYTQAVFVEFTVYNANVNL
FCIVTLMFETTATGAFQFRTELQNVRLYQSTGGLHIFVMASEAIYFLFIFYYMVVQGKLM
RQQRWAYFRSKWNLLELAIIILSWSALSVFIKRTLLGKRDIEYYQSNKDQYASFHETAKA
DAVLGYLIAFLVLLATIKFWHLLRLNPKLHMITATLQRAWADISGFLVVMAIMFLAYSIA
SNLMYGWKLYSYRTLLDAAQTMISLQLGIFNYEEVLDYNPVLGAFLIGSCIVFMTFVVLN
LFISVVLVAFSQEQIYHKPSEDEEIVDLMLMKLGSLFGLKCKKQGGEDQTRNATSSNNEP
ST

>Tetraodon nigroviridis_PKD1L2a(ENSTNIP_6576)
SCYEVVGLRYTFSGARAWCEQRGGHLACIPDKETQLFLQRHFDPNEDFWFGARAAPQKLH
KILQGGLSWLDGSPVTSSARARIPQPGSSCGRILGGQEFQWEATSDCTKKLPFICQFGLW
RSTVCGYGSTTLQCCSEQALAVNGGFHGQKNSYYCWSRQPALTTPPHVQCGWVDVTKPQT
VQGLEICAHQMLCDGNQFERACPAKTLISQIYYMNTAGIILSAGSAAAVYDDVAIKVQWL
LQPSGGNFSCKLSTGDGHVINLERPEALEIRVVHRYVHPGTFTVAAQCSSADTDVTACKL
IAVHWPVRAFTSFACYAGNLSLNASNCKALHGEQLQIQMGVNAGSKVTYRILIDNITLPG
FCSWRGNVPVNVTMAPDIIDQLGIGCHHLRIYASNAVTFPDVSTRPNFVICVLEKIHGLQ
ASVLADEEANVDLESITVGVSLERGLPALLLFTLLQNNNSISKSAETNVLKSWLFHAAEL
LYFMSFYVMSFFPFFTAGCMKIKLRAWNTFSSVEVDVDTFATCSKDKDIKTVKYILLHFW
NFTVFRKKNMQELPGLTSHWLSKQYLTQFNECVNIVVITEGLSFVVRKDCLPHPFQFFTY
RFSVINVADNNVDKSQFICITVTPQKALGNTGVRVACKQGCDPATMSKDAIIIWTAKIKY
SHTLFLSLLSLLPDATTTVYTKYTINPRSLQPTATTVPNPHVNVDSFTRPITLGPTSMLP
GNNNGLLTASVGADSLTHLTTPRPTGIIPDCTIAPLSGTMFDAFNITCNTDFICSNCQYC
FRTLQGNPLQCSNNKEVVSIFLPPGNKNLNYDLSIIATAQDGSFVARAIITARVCKRPVG
QNSSSSDDDLVEDIVAKLKKQESVGQIIKVMSDGINSQSSNAEQQKVCLSKLRYLLLRVM
TTTVKTVPITTPAAIQKAARALTDVVRSGSELGSSAAEEASVILANLSAALLQMEVDNSG
EIVMVAKTIVEGVGNILEYASIVGIGSCVIKDCTFISQRNVSDAILMALKNTQRALLKDK
KVNQGPVVIKDDNINMLVDRVTPDRLHRNSIKIPDCFCLAFSLPKLPSTLIPPGEPVDVQ
MLTLDKNPFAWNEGGNISGVVGALSLATQDGSLITVENLSEDIEILIPRPPGAPVVSSVL
DLGNYSTIVIDLPTADSTVLLKLKMVPSVDPLPFKVFLGYYKYPTYTDFVAMAEMPLQGA
ITEEKYTWILRPKDFKGCRGEHYLVVRPVVGAGIKSINASLTITAITAECKFWNESYLDW
SADGCRVGVQTTHLVTQCLCNHLTFFGSSFFVTPNLVDPSRSAELFGTFAENPVVVCFVG
ALFVVYFLVLVWARQKDIQDTTKVKITVLQDNDPLDEYSYLLSVSTVHRRGASTSSQVME
SSVWVKGLATPHKGLAPCHITFKNIDLLRFCHLICRFVGTVMVQDLQTGQKWHFLCNTWL
AIDMGDCSLDKVFPVSTELDLMRFSNLFFMKASKDFSDGHLWYSVISRPPSSTFTRVQRV
SCCFSLLLCTMLTSIMFYGIPSDPSEQTMDLGHFEFTWQQFMIGVQSSLIMFPINILIVS
IFRHTRPREPCCCKRKRDALDMPGRTCFSPTDTQAINDHVTLETVMKDITRITHSLSKSV
KSNIPCTKVELEQQTDINAVLSVMEGFIKQTFKTKPRLPDFQHTLNLKQPIINGLFSEGR
LAAEEFPKKSRMNRIQYLHQQLSHIEKGLRLVGPSGFHSPHSYGQAMQQVKDMRNFLEDH
IFNFSHVDLAEPTHNQTNCCRGGFPWWFIFFGWLLVIATSVVAGYFTMIYGLKFGKERSI
SWLISMIVSFFQSILIIQPLKVVFLAIFFALVIKKVDEEDYQHMAVAENDSHPGELKDPQ
TVRQGSSLYQPPAPADIERMRKNRILEQKAVAGRRECRIHIGFMWMLLLVAYGQRDPNAY
FLQKHIKESFSRNISDSMSLGDVFSWADTVLLRNLFGEHSGFITDGNSKLVGNARVRQLR
VRRNSCQVAGSMQRLVARCHAPYSWEVEDRSSYGPGWNHSSRNQTTGMPNPWTYQTQAEL
RASQAWGRMLLYGGGGFAAELGPDLQNASRTLEYLFSNKWLDGYTRTIFVEFTVYNANVN
LFCIVTLLLETAAVGAFQFTSDLQTVRLYQSTDGLHVFVMAAEIIYMIFILYYMFVQVKL
LKKLRWLYFSCKGNIFELTLIVLSWSAVAVFIKRTLTGNRDMTYYQNNRTQFASFYETAM
ADSTLRYLIAFLVLLSTLKLWRLLRLNPKMNIFTATLQQAWSDITGFLLIIAIMFTAYSI
VSNVMFGWQLSSYRTLARCLVTIISLQIGIFNYDEVLNSQPLLGGFLFGSCIAFMSFMAL
NLLISVILVAFSNEQKHHKPSDDEKIFSLMLGKICSLFGIK

>Tetraodon nigroviridis_PKD1L2b(ENSTNIP_8467)
MLQQTAGAWSIHTRLFNSEWKPGLTLNISSFMTKCVYWHTEREVWSTDGCQAQKSTATQA
QCLCNHLTLYGSSFFVMPNDVDISRTAELFATVSQNYVVLALLCAFFGLYLITLLWACYA
DRRSRSKWKMTLLEDNHAGALYNYLISVQTSRRKNAGTTANVTLKLSGSEGESDIHTLTD
PDKPVFERGAVDLFLLATPFPLGEVRNIRLQHDNTGGYPSWYVNKVTVQDLQTRQVWHFL
CDCWLSADRGDGMTKKTFNAAKNNEIASFRNIFQSRTSTGFRDEHIWVSVVDPPSRSPFT
RAQRVSCCMSLLLCTMAINIAFWNLPVDEKSPITWQEIMVGVESGLLMFPINIFIITIFR
SIRPRVVSKNKANSERNVRPFAVTVPSILKVCTLHLL

>Gasterosteus aculeatus_PKD1L2a(ENSGACP_2802)
CSISPQSGTILDVFTIMCNTPCSNCRYCFKTDMGHLLRCSNNNEIKSVFLPLGDSSFDYI
LTVTATAKNGNYVWSTTITAKVCQVMDPCSPVDDIKASLENAVAQLKKQGLLSAETVGQL
INSVSNKLNSQSDQANSADRQKSKLREKMLDILMNTVKEAPTLTPEEVQVIARALAAVIQ
MGTELSRCAQEKASLLFENLSSDLLCMKVIESEDTVIEIHAAVSAILEGVCRILDFSCNV
SVSPSSSSPPKIACDAALLTLSNTQSALLAFKDVDKAPTIIRERHLCVFVNRVTVGNLHK
EIINTPNCSSMTFSLPALSKIGPSYEPVDVRMLTLEQNPFCWNKRGSISGKIGAVSLTRE
DGSIIPVENLSENIKILIPRPEGEKVKTSVLDLRDYSTTVIDIPSDDSTLVLKVQMVPSY
DPLPLKLFLGYMDYPTKTNHVAMTEMPHQGETQEERYTWLLDAKDLKGNRGKHYLVVRPI
VGPGIKSINASLSITSFTTACKFWNESTLEWSTFGCRVGVQTTPLVIQCLCNHLTFFGSS
FFVTPNLVDPSRTAELFGTFGENPVVVCFVGALFLVYLLAIVLARRKDIKDIVKVKVTVL
ADNNPMDENGYLLSVSTGYRRGASTSSQVTITLLGAEGTSEPHHLTDQKKCVFERGAVDV
FLLTTPFSLGDLQGIRLWHNNSGSHPAWFVGNVAVHDIQTDQTWHFQCNSWLAIDIGDGT
VDKVVPVSTEMDMKRFSNLFYMKTTKDFSDGHLWYSVISRPPGSNFTCVQRVSCCFTLLL
CTMLTSIMFYGIPTDPSEQTMDLGPFEFSWQQFIVGVQSSLIMFPVNILIVSIFRNTRRR
ETSCCKRKTKKPRARGGPGMDPGPQGRRSGTLAVAKDDITRIACSLSNNMKSKIQNMESG
QGVDINAVLSMVEDFIKPQPPGIYRVFFIEQDKHRTLAYVLQCREHSLCQFCTFPEGSPG
STMEGIQKKSSKTQYLYRQLCHIDKRLSLLGPSGFPTPHSHSRALQQIQGIKECLEDQLS
TVRCVNPDETTQNKYIGGLPWWFVFVGWLLVIACSFVSGFFTMLYGLKFGKDRSVSWLVS
MCVSFFQSVLVIQPLKVLCLAVFFALIIKKVEDEDFRNVEFEGNLEQMNTFLPSGDVKDQ
QMNKRDPSLYEPPPAADIEKMKRNTVMQQKAFALLKEILTYVGFMWMLLLLAHGQKDPNV
FFLHRHIRDSFSSQTSDSMSLTDVFTWANTLLLSNLFGVYPGFITDGNSKLVGNARLRQL
RVQSNSCQIAAPMLHFAPDCNAPYSWEAEDMGSYGTGWNRCTSGPWTYQTQSELRSYPIW
GQMVLYRGGGYVAELGPDSQNATSTLDYLFKNRWLDVYTRAIFVEFTVYNANVNLFCIVT
LLLETSAVGAFQFHSELHSVRLYQSTDNLHIFVVAAEIIYLLFILYYMFLQGKLMKQQRW
TYFRCKWNLLELTIILLSWSAVAVFVKRTLLGNRDMTYYENHKHQFASFYETATADSALQ
YLVAFLVLLATFKLWHLLRLNPKMNVITAALQRAWNDICSFLVVILIMFVAYSVSSNLIY
GWKISSYKTFTDALLTIIGLQIGIFNYDEVLGDSPLLGGFLFGSCIVLMTFVVLNLLLSV
ILVAFKQEQLHHKPSDEEEIVDLMLKNICSLFGIR

>Gasterosteus aculeatus_PKD1L2b(ENSGACP_20781)
MERTMFHTLTAMVLFLTCSAQEDAEALPCPEYQESFDGSCYEFVSLQRPFLGAQGWCEQG
GGHLAFILNDETQQFLQKHLDPEKDWWLGLAPAAPNLTLDSADTEGSLAWLEGSDVSYSN
WANMPDALAACGHILRGSGFQWEAADDCNQELNFICQFDSGRSIACGGQNATLQCGSGQV
IIIDDSFYGRKTIHYCRAELAASPTSSQEECSWIDVMESVTAHCHSRQTCQAPVDLSSFG
EPCPVLGSYLSVEYTCKHGLHLLMSKLAAIFDNVTITVKWLLNPFQGNLTCTLNAGDGHI
INPYNPEETESNVMHKFTRPGVFVVGVECTTSDWHVTAQEAITIQEPVGEFGVIKCYSRN
MSTGGTECNVHSGTPVQIQVMVRAGTNVSYTIQHGGYVVANLSVENGITPHNMTLSLSTV
EKLGHGCHNLTLSASNKVTGQAVSADLKLCLLEPIEGLQASVTAEEDVCPDSTDLIIGVS
LERGAPVELLFTLTGGGGTISEARDMLNGGSQAYTFSRPLQGTLKVTLRAVNAFSASDVD
VDLEDILRSCQNQSDFSADTASLSIDNLKITAIPDTLVDNTQSVTLRVSGTESMASKGLV
FEWKCEGNCKCRNKTKGETHVIAKNCLPDPFDIFEYILTVRRATWFRKWVDSASASKCIT
VTPKEFTDVTIRVGGSCDDCSSINVNNAVKLRLSCVKTCQEVVWYIEDPKPLADDLKKCH
SKEGRRPIIERQDGNTEYVVRSQHLKISRDSSHNISVIAYGKNMPGFAKYTLPIPGPEPT
EADNLPPSCNISPPSGTVLEPFDITCKSSSFCSTGCFYCFKTDTGEHLRCSKANEVRSVF
LPLGDKNNNYTLLVVVTVKNKYEKTSTTVSTQVRTSSTSTSVEALTSAVEDSVGQLEQQG
LLSCEALGQIFSSVSDLLNTEDGQDQRDARTKLRKQMLSKMTRVLLDSPSNTTQEVQVTA
RALAGLTQRPDELSAAAQEEAGSLLVDLSSSLNTITGNQDDGEDGEVVRAATPILEAASN
ILNVSSNIYSIMYHIMYSPQKKVSDSLLTGISNVQSALLNNKKLNGDPAIIDSGQISVYV
NRVSPENMQDINVQKSSTSRFFFPALPAHILSPEEPVDVRMMSFEKNPYSWKEENITGTV
GSVSLTRTNGSVISVQNLPEEIEIFLPRPDVGQENSTVLDLANFSTLIINVPSPDVTLVL
KMEPSEQLTFMLFLGSKDYPNDENYLAKTQMPLQNAKGEGKYTWVLSPKDRTGEVGEHYL
VMKPIVEPGIKAVNATVTVISIAAQCKYWNENESSWSEDGCRVGPLTTPLVTHCLCNHLT
FFGSSFFVMPNLVDVSRTAELFATFTNNPVVVCFVGAIFAAYLLVVVWARRKDIQDSAKV
KITVLEDNDPLAEYHYMLNVSTGHRHGASTSSRVTITLLGTEGESEPHHLTDTEKPVFER
GGVDMFLLTTHFSLGDLQSIRLWHDNSGAHPAWYVNKVMVQDLESGQKWHFLCNSWLAVD
VGECALDKVFPVATEMDLKRFSNLFFMKTAKDFRDGHIWFSVISRPPCSTFTRVQRVSCC
FSLLLCTMLTSIMFWGIPTDPSEQTMDLGHIEFTWQQVVIGVQSSIIMFPINLLIVSIFR
NARPREKGSKRETSKQGKTGRVSPSQTSSPQKALKDITPDTVIKDIKRIAQSLSKAMKSP
LPQLELRPGQQSDINTLLSLVENIIRQQNRAAGDFYTDASKRDTSMILSLQAVNLEQAEN
CGVGSPEKTSDEVQKKSSNSRYLYKQLRHVEKELGLLGLSRFPNPDSYNRAMQQVKGMKG
LLECRLHPPSLEGDELDRSPSPGGLPWWSVFIGWILVIATSGVSGYFTMMYGLTYGKERS
INWLISMMISFFESLFVTQPLKVLGFAAFFALVLKKVDQEEYGEPPIDESLRNTGDPDTV
RAARRDSTCSFYQPPPPTDIEKIRSNMIKEQKVFALIREILAYMGFMWMLLLVAYGQRDP
NAYFLTQHIRQSFSRGISDSMSIEEMFNWANTTLLSNLFGEHPGFITDGNSKLVGNARLR
QVRVHQNSCHVAPSMQRSERDCHAPYSWELEDMGSYGPGWSHSEGDNTSLNLRSLWKYQS
QHQLRAIPVWGSVQLYRGGGFVVDLGPDLINSRRSLQYLYDNTWFDVYTQAVFVEFTVYN
ANVNLFCIVTLMLETTAIGAFQFRSELQSVRLYQSTGGLHVFVMASEVIYFLFIIYYMFV
QGKLLKQQRWAYFRSKVNLLELAIILLSWSALSVFIKRTVLGKRDMEYYQDNKDQYASFH
ETAKADAVLGYLIAFLVLLATIKLWHLLRLNPKLHMITATLQRAWADISGFLVVMTIMFL
AYSIASNLMYGWKLYSYRTLLNAAQTMVSLQLGIFNYEEVLNYNPVLGAFLIGSCIVFMT
FVVLNLFISVILVAFSQEQIHHKPSEEDEIVDLMLMKLFSLFGVKCKKPAGDCTTERP

>Oryzias latipes_PKD1L2a(ENSORLP_9492
ATRITFTLMLLFHSSMCSAEEDEEGLFCPEDQRGFDDACYEFVGFQLSSQKAQAWCERGG
GHLAFILSDEIQQFFQTHLHPDKDWWIGLAPVAANLTLDFSSTEGSLAWLDGSDVSYDNW
ANAPDAGATCGHILRHSGFQWEASQNCGQEFNFICQFDTGKTIACENQNATLKCGSGQMI
EIEDAFYGRKTVHYCQSKQNSTPSLSQQECSWINVVDSVTAHCHGQQACQVPVDLNLFSE
PCAVLGSYLSIEYHCKQGLHLLISKLASISDDVTITVKWLLHPFQGNLTCAVNAGDGYII
DPYIPEEMESTVIHKFQHPGVFTVEVECSTSDWHVSAEKSITIQEPVGGLSVTRCYSRDV
ATDGTKCNALLSMPVYIQLQVEAGTNVSYTVHHEAHVIANLSVDNGIAPTNATLNASVVQ
RLGQGCHNLSVTASNRVTSRTASSGLVLCLLEPVEGLQASLITEEELCPDSTDLIISVSL
EQGTPVELLFNFSGTADTLTEMRHMFNKSGQMYTFSNPLEGTGLSKVMIRATNAFSSSDV
EVDLVEVLRPVKVNPGSFFLQQRSNESISDLKITTSPDTLVDYSQNLILMERGTESLPSK
SLAYEWKCKENCMCRNITKEKTHVIEKDCLPKPFEIVEYTLTVRKRTWFRKWVSLASASK
CITVTPSKVLAGVTISCENCASINVNDQAKLRLRCVTVCPDVVWFIEDPKPLSVKCYFKA
GRRPPIESQDSHTEYVVPSRYLEASRRMLHNITVIVYVPGFHPEVTFDPPAVPSCSISPP
SGTVLQTFDITCEAKSFCEAGCLYCFKTSTGFKGKDLWCTSANKVKSIFLPSGDETNNDT
LTLMVTVKNKYTTINTTVAAQVRKGNSSTTVTVLGYAVEKSVSQLEEQGLLSSEALGQIF
TSVSDILNSEWGQEQKDNRSKLRERMLTKMTGVLLKSPSNTTQEVQVMARAVAGLTQSSD
ELSDVAQEKATSLLVDLSSSLNVITVNQLGGDDEVLQAATPIIESASNVLNVSLSSVRTE
PSLIFSNAILQSSDSLLTGIKNIQSALLNNRKMNGQPAIIDSGQISVYVNRISPDSIQMQ
NINGVRNSSSRFSFPSLPADILSVEDPVDVRMISFEKNPYSWMEENITGTVGSLSLTRAN
GTVIPVENLPEEIEIFLPRTDMGQENSTVLDLAYFSTLMIDVPSPDVTLVLKLQPSEDLS
FILLLGYKGYPNYTNYVAKTQFPLENINEEEKFTWVLRPKDRTRDVGVHYLVIKPIVEPG
VKSINATVTVISVAAQCKYWNESTSSWSEDGCRVGPLTTPLVTQCLCNHLTFFGSSFFVM
PNLVDVSRTAELFATFANNPVVVCFVATIFAAYVLVVLWARRKDIQDSAKVKITDLGDND
PLAEYRYMLTISTGHRRGASTSSQVTITLQGTEGESEPHHLTDPEKPVFERGGMDMFLLT
THFSLGELQSIRLWHDNSGDHPAWYVNNVMVQDLELGHKWHFLCNSWLAVDVAECTLDKV
FPVATETDMKRFSNLFFMKTAKDFRDGHIWFSVISRPPCSTFTRVQRVSCCFSLLLCTML
TSIMFWGIPTDPSEQTMDLGHIEFTWQQVIIGIQSSIIMFPINLLIVSIFRNSRPREKVT
KTDVSKQGNTVRVSPSETSSSQMEMKNITPDTVIKDIKRMAKSLSKAMKNPFPHLELGPD
QHADINTLLTVLENIIRQQNEATESFYSDTSKTDNAMILTLGSVNLQGTENSVWSSPVKT
PKDFQKISNNSKYLYRQLHHVEKELGLLGPSRFPNPNNYNRAMQQVQGLKSHLESSLDGD
KPSPEGSINGSTKKKQIQRGLPWWFVFVGWILVIATSGVSGYFTMMYGLTYGKDRSISWL
ISMVVSFFESLFITQPLKVLGFAAFFALVLKQVDLDEFGEPQIEENFKRTDDPEVVPADR
RDSTCSFYQPPPPTDIEKMRNSMIKEQKVFSLIKEILGYMGFMWVLLLVAYGQRDPNAYF
LTRHIRQSFSKGISDTMSIQDVFTWANTTLLNNLFGEYPGFITDGNSKLVGNARLRQVRM
QKGSCLVALPMQISVPDCHALYSWELEDTGSYSPGWSPLSGNNATLNPHNPWIYKSQHKL
RAYPICGNVKLYRGGGFATDLLPDLKNSSRVLQYLYDNIWLDVYTQALFVEFTVYNANVN
LFCIVTLILETTATGAFQFRSELQSVRLYQSTGGLHIFVMASEVVYFLFIIYYMFVQGKL
MKRQRLAYFQSKWNLLELAIIFLSWSALSVFIKRTLLGQRDVSQYENNKDQFVSFHETAQ
ADAVLGYLIAFLVLLATVKLWHLLRLNPKLHMITATLQRAWTDISGFLVVIAIMFLAYSV
ASNLMYGWKLYSYRTLLEAAQTIVSLQLGIFNYEEVLNYNPLLGAFLIGSCIVFMTFVIL
NLFISVILVAFTQEQIHHKPSEEEEIVDLMLMKLCSLFGLKSKKKDDALTEEAPISSALE
TKQLTISTTD

>Oryzias latipes_PKD1L2b(ENSORLP_22696)
ILHLLILWTSISQASSENEVKVAPFCPSDQKAFGRSCFAFVNQQQSFPAAQDWCEKSGGH
LAFIPDKNTQNFFEKHLDPDKDAWLGMAPSTSTRNRQHMEAVSSSGALSWLDGSPLTYSK
WLRTPQPGAACGHILRSSSFQWEATSDCYQEMNFICQYESGRKIVCAGHDTSLECSSKEV
LMIDSSFYGRESIHYCRSGVSAPASLQKECGWVDVKATITARCHGQRICNITKVMNSLDE
LCPRRRSYLSVKYHCSDAGLSLSVKNVAAVLEDVVIEVKLLANVQDLLCRLQTGDGQTIS
FRPPQGLRSSVMHKYTHPRTFVVKCECSSSSGQMHFTAHKTVTIQEPVREIGAIRCYTRK
KSFSETKCTALRGEAFQIQMGVKAGTNVAYRIQIGEQFLAGLSVFQGNVPKNISVMADTV
KQLGSGCHRLTIYASNMVTTPEVSSDLQVCVLEKISGLQASILKDTVDPFGAHRVAVGVS
LTRGAPVFLSFLMKGEHSSLVETRKMDVKRGTFVIQCPAKECVQIKIRARNAFSSQKVDS
LTGFKKKQVRECLHQYVQEKRLVRDSRSVVEISASPASVTSTSDSIVLSLSDETILRGVS
RFEWNCRQRWIKTKACFKLGSSSSFCVTHTMMFVILEDKSGLNLKNILGTHIKKNNSSCA
YQIAGKLLLPRVTCKDGCTVQGKIEDANIELSCDSSCPTVDWYIQETDDEIEKESRKTSY
KVKKQRISDAGKRNQNVTVVIIFVSLFRPTCSTVLRIYFKYKNQTTEGTPTNVELLSCVA
TPSTGTILDAFNLTCTTQQPCVGCQFCFTADFSDKQLRCRESKEVQTVFLPLGNISSNYS
LLITVTVANGSESLNTTFTVQVLDFTPTPNSTDDLHAAVVNTLEKLQTNGQLSGETVGQI
FSSVAESLNNKPDASKIGGHKQRKLREEMVDTMVNIINEAPPSTPKDAQALAEGLTALAW
ERAELRVSAQISASSLFETLSLSLMNMNVSRTEDGRNQVLAAASTIVVGIDTMLNYSFME
GIEKCSSFWKNVSDALLSALSNIQSALLKLKEPNEGPTLLKTVLIRVLVNRVTPDSLLAQ
NLSFVESSLPNFTLPKLPTNLLPSDGPVDIRMLSLAKNPFSWNEKGNISGLIGSLSLSTK
DGSGIPVENLSEDIEILLPRPAGEQVNTTVLDLVNYSTTIIDVPSADTSLLIKMVPSLDP
LPFKVYLGFIDYPTETNHVAMTQMPLQGTTEEEKYTWIVRPEQLKGNTGAHYLVVRPIVG
PGIKSVNASLSVTTIASSCRFWDESILQWSTTGCKVGVKTTSMVTQCLCNHLTFFGSSFF
VTPNLVDPSQTAQLFATFTENPVVVCFVGALFVTYLLVVVWARRKDIQDTAKVKVTVLHD
NNPKDEYRYLLCVRTGHRIGASTSSQVIVTLLGVEGNSEPHHLTDQRKPLFERGAVDMFL
ITTPSFLGELQGIRLWHDNSGSHPAWYVANIMVQDLQTEQKWNFLCNSWLALDVGDCCID
RIFFVSTEEELKRFSNLFFMKTTRDFCDGHLWYSVVSRPAGSNFTCVQRVSCCFSLLLCT
MLTSIMFYGIPTDPSEQVMDLGHFEFTWQQFMIGVQSSLIMFPINVLIVSIFRNTRPRES
SCCGGRKKKPKSIPKDGTLETVSSQDVTRLADLLCKRTKSRFGPEEETEINTILFKMEDV
IQERRKTGDKGLFHLPVTKQSPNINTKRELKTQKSSAHLNPPSVVEATKKKSNKMQHLYR
KLCDIDKELSLLDPSSFQKPNSYSQALQQVQSMKGLMFRPADGAAMNGGGKKSLCCRGML
PWWFVFVGWLLVIATSVVSGYFTMLYGLKFGKLLSKIRLGVTGTFIDSANFINTPLKLRS
HRMVFTHNLTREKLTYPLQHKHSGFGVEASTGEKKDHDASGWKSLLYEPPPPAAIERMKR
NKIMQQKANALLKEILIYIGFLWMLLLVAYGQRDPNAFYLNQHIRNSFTGEASDSMSLQD
VFTWANTTLLKNLFGEYPGFITDGNSKLVGDARVRQVRVKEDSCQIAGLMLPLVPECNAP
YSWDLEEMGSYETGWNRTGRENFSASTPSPWKYQTQTQLRGRPFWGKTALYRGGGFVVEL
GPDLSNASRYCTLEYLFENKWLDLYTRAIFVEFTVYNANVNLFCIITLLMETTAVGVFQF
YSELQSIRLYQSTGGLYVFVMAAEIIYLLFILYYMFLQAKLMRLQRWDYFKNKFYLLELS
IILLSMSAVAIFIRRTLLGNRDVAFYQTHRDQFASFYDTATADLQLQYLIAFLVLLATVK
CWHLLRLNPKMNLITAALQRAWNDISGFLLIFGVLFVAYSITSNLIYGWKLSSYKTFTDS
LLTVISLQAGIFNYDEVLNDDPVLGGLLVGSCIVFMTFVLLNLLISLVLVALKTEQLNHK
PSEEEEVVDLLLSNIFSLFGIRYKDTATDSS

>Homo sapiens_PKD2L1(ENSP_325296)
MNAVGSPEGQELQKLGSGAWDNPAYSGPPSPHGTLRVCTISSTGPLQPQPKKPEDEPQET
AYRTQVSSCCLHICQGIRGLWGTTLTENTAENRELYIKTTLRELLVYIVFLVDICLLTYG
MTSSSAYYYTKVMSELFLHTPSDTGVSFQAISSMADFWDFAQGPLLDSLYWTKWYNNQSL
GHGSHSFIYYENMLLGVPRLRQLKVRNDSCVVHEDFREDILSCYDVYSPDKEEQLPFGPF
NGTAWTYHSQDELGGFSHWGRLTSYSGGGYYLDLPGSRQGSAEALRALQEGLWLDRGTRV
VFIDFSVYNANINLFCVLRLVVEFPATGGAIPSWQIRTVKLIRYVSNWDFFIVGCEVIFC
VFIFYYVVEEILELHIHRLRYLSSIWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQ
QPNTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGF
AVMFFIVFFAYAQLGYLLFGTQVENFSTFIKCIFTQFRIILGDFDYNAIDNANRILGPAY
FVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDELQLSDLLKQGYNKTLLRLRLRKE
RVSDVQKVLQGGEQEIQFEDFTNTLRELGHAEHEITELTATFTKFDRDGNRILDEKEQEK
MRQDLEEERVALNTEIEKLGRSIVSSPQGKSGPEAARAGGWVSGEEFYMLTRRVLQLETV
LEGVVSQIDAVGSKLKMLERKGWLAPSPGVKEQAIWKHPQPAPAVTPDPWGVQGGQESEV
PYKREEEALEERRLSRGEIPTLQRS

>Pan troglodytes_PKD2L1(ENSPTRP_5000)
MNAVGSPEGQELQNLGSGAWDNPAYSGPPSPHGTLRVCTISSTGPLQPQPKKPEDEPQET
AYRTRVSSCCLHICQGIRGLWGTTLTENTAENRELYIKTTLRELLVYIVFLVDICLLTYG
MTSSSAYYYTKVMSELFLHTPSDTGVSFQAISSMADFWDFAQGPLLDSLYWTKWYNNQSL
GHGSHSFIYYENMLLGVPRLRQLKVRNDSCVVHEDFREDILSCYDVYSPDKEEQLPFGPF
NGTAWTYHSQDELGGSSHWGRLTSYSGGGYYLDLPGSRQGSAEALRALQEGLWLDRGTRV
VFIDFSVYNANINLFCVLRLVVEFPATGGAIPSWQIRTVKLIRYVSNWDFFIVGCEVIFC
VFIFYYVVEEILELHIHRLRYLSSIWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQ
QPNTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGF
AVMFFIVFFAYAQLGYLLFGTQVENFSTFIKCIFTQFRIILGDFDYNAIDNANRILGPAY
FVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDELQLSDLLKQGYNKTLLRLRLRKE
RVSDVQKVLQGGEQEIQFEDFTNTLRELGHAEHKITELTATFTKFDRDGNRILDEKEQEK
MRQDLEEERVALNTEIEKLGRSIVSSPQGKSGPEAARAGGWVSGEEFYMLTRRVLQLETV
LEGVVSQIDAVGSKLKMLERKGWLAPSPGVKEQAIWKHPQPAPAVTPDPWGVQGGQESEV
PYKREEEALEERRLSRGEIPMLQRS

>Mus musculus_PKD2L1(ENSMUSP_45675)
MNSMESPKNQELQTLGNRAWDNPAYSDPPSPNRTLRICTVSSVALPETQPKKPEVRCQEK
TQRTLVSSCCLHICRSIRGLWGTTLTENTAENRELYVKTTLRELVVYIVFLVDICLLTYG
MTSSSAYYYTKVMSELFLHTPSDSGVSFQTISSMSDFWDFAQGPLLDSLYWTKWYNNQSL
GRGSHSFIYYENLLLGAPRLRQLRVRNDSCVVHEDFREDILNCYDVYSPDKEDQLPFGPQ
NGTAWTYHSQNELGGSSHWGRLTSYSGGGYYLDLPGSRQASAEALQGLQEGLWLDRGTRV
VFIDFSVYNANINLFCILRLVVEFPATGGTIPSWQIRTVKLIRYVNNWDFFIVGCEVVFC
VFIFYYVVEEILEIHLHRLRYLSSVWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQ
QPDTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGF
AIMFFIVFFAYAQLGYLLFGTQVENFSTFVKCIFTQFRIILGDFDYNAIDNANRILGPVY
FVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDQLQLSDFLKQSYNKTLLRLRLRKE
RVSDVQKVLKGGEPEIQFEDFTSTLRELGHEEHEITAAFTRFDQDGDHILDEEEQEQMRQ
GLEEERVTLNAEIENLGRSVGHSPPGELGAEAARGQSWVSGEEFDMLTRRVLQLQCVLEG
VVSQIDAVGSKLKMLERKGELAPSPGMGEPAVWENLYNPS

>Rattus norvegicus_PKD2L1(ENSRNOP_62794)
MNIMENSKEQELQTLGSRVWDNPAYSSPPSPNGTPRICTVSSVALPETQPKKPEVRRQEK
TPRVPVSGCCLLICRGIRGLWGTTLTENTAENRELYVKTTLRELVVYIVFLVDVCLLTYG
MTSSSAYYYTKVMSELFLHTPSESAVSFQTISSMSDFWDGPLLDSLYWTKWYNNQSLGSS
SHSFIYYENLLLGVPRLRQLRVRNDSCVVHEDFREDILNCYDVYSPDKEDQLPFGPLNGT
AWTYHSQNELGGSSHWGRLTSYSGGGYYLDLPGSRQASAEALQGLQEGLWLDRGTRVVFI
DFSVYNANINLFCILRLVVEFPATGGAIPSWQIRTVKLIRYVNNWDFFIVGCEVIFCIFI
FYYVVEEILEIRVHRFRYLSSVWNILDLVVILLSIVAVGFHVFRTLEVNRLMGELLQQPD
TYPDFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAIM
FFIVFFAYAQLGYLLFGTQVESFSTFVKCIFTQFRIILGDFDYNAIDNANRILGPVYFIT
YVFFVFFVLLNMFLAIINDTYSEVKEELAGQRDQLQLSDLLKQSYSKTLQRLRLRKERVS
DVQKVLKGGEPEIQFEDFTNTLRELTRRVLQLQRVLEGVVSQVDALSSKLKMLERKGELA
PSPGMARGASCLGEPL

>Canis familiaris_PKD2L1(ENSCAFP_14182)
MNAVESPEGQELQKMGSGAWDNPAYSGPPSPRGTLKICTISSAMPPQPQIQKPEDGPQEK
AYRTLVSSCCFQICRGIRGLWGTTLTENTAENRELYVKTTLRELLVYIVFLVDICLLTYG
MTSSSAYYYTKVMSELFLHTPSDTGVSFQAISSMADFWDFAQGPLLDSLYWTKWYNNQSL
GHGSHSFIYYENLLLGVPRLRQLRVRNDSCVVHEDFREDILSCYDVYSPDKEEQLPFGPL
NGTAWTYHSQDELGGSSHWGRLTSYSGGGYYLDLPGSRQASAEALQDLQEGLWLDRGTRV
VFIDFSVYNANINLFCVLRLVVEFPATGGAIPSWQIRTVKLIRYVSNWDFFIIGCEIIFC
IFIVYYMVEEILELHIHRLHYLSSIWNILDLVVIMLSIVAVGFHIFRTLEVNRLMGKLLQ
QPNMYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGF
AVMFFIVFFAYAQLGYLLFGTQVENFSTFIKCIFTQFRIILGDFDYNAIDNANRILGPAY
FVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDELQLSDLLKQGYNKTLLRLRLRKE
RVSDVQKVLQGGEQEIQFEDFTNTLRELGHAEHEITELTAAFTRFDQDGNHILDKKEQEQ
MQQDLEEKRVVLNAEIENLGQSIVSSSPGESGPEATRADGWVSGEEFYTLTRRVLQLETV
LEGVMSQVDAVGSKLEMLERKEQLASSPGMGDQGIWEHLQPTSPVTPDPWGVQGGQESEF
PGGREGEALEEMRLSHIGDYSVAEEL

>Felis catus_PKD2L1(ENSFCAP_5991)
MNAMGSPKGQELQNMGRGAWDNPAYSGPQSPHGTLRICTISSVMPPESQPKKPEDGPQKK
AYRTLVSSCCFQICRGIRGLWGTTLTENTAENRELYVKTTLRELLVYIVFLVDICLLTYG
MTSSSAYYYTKVMSELFLHTPSDTGVSFQAISSMADFWDFAQGPLLDSLYWTKWYNNQSL
GHGSHSFIYYENLLLGVPRLRQLRVRNDSCVVHEDFREDILSCYDVYSPDKEEQLPFGPL
NGTAWTYHSQDELGGSSHWGRLTSYSGGGYYLDLPGSRQASAEALQDLQEGLWLDRGTRV
VFIDFSVYNANINLFCVLRLVVEFPATGGAIPSWQIRTVKLIRYVSNWDFFIIVCEIIFC
VFIFYYVVEEILELHIHQFRYLRSIWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQ
QPNTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGF
AVMFFIVFFAYAQLGYLLFGTQVENFSTFIKCIFTQFRIILGDFDYNAIDNANRILGPAY
FVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDELQLSDLLKQGYNKTLLRLRLRKE
RVSDVQKVLQGGEQEIQFEDFTNTLRELGHAEHEITELTAAFTRFDQDGNHILDKKEQEQ
MQQDLEEKRVALNAEIENLGRSIVSSPPGELCPEATRAGGWVSGEEFYTLTRRVLHLETV
LEGVMSQVDAVGSKLKMLERKGQLALSPGMGDQGAWEHLQPAPAMTPAPGDQGGQESEFP
GEREGEAVEERRLSQ

>Bos taurus_PKD2L1(ENSBTAP_14222)
MNAVGSPEEQELQELGSGAWDNPTYSGPPSPRGTLKIYTISSAVLSQPQPKQPEDGPQEK
AHRTLVSSCCLRICHGIRGLWGTTLTENTAENRELYVKTTLRELLVYVVFLVDICLLTYG
MTSSSAYYYTKVMSELFLHTPSDTGISFQAISSMEDFWDFAQGPLLDSLYWTKWYNNQSL
GHGSHSFIYYENLLLGVPRLRQLRVRNDSCMVHEDFREDILSCYDVYSPDEEEQLPFGPL
NGTAWTYHSQDELGGSSHWGQLTSYSGGGYYLDLPGSRRACEEALKDLKEGLWLDRGTRV
VFIDFSVYNANINLFCVLRLVVEFPATGGAIPSWQIRTVKLIRYVSNWDFFIVGCEIAFC
IFIFYYIVEEILELRIHRLRYLSSIWNILDLVVILLSIMAVGFHIFRTLEVNRLMGKLLQ
QPNMYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGF
AVMFFLVFFAYAQLGYLLFGTQVENFSTFVKCIFTQFRIILGDFDYNAIDNANRILGPVY
FVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDELQLSDLLRQGYNKTLRRLHLRKE
QVSDVQKVLQAGEQEIQFEDFTNTLRELEHTEHETTKLTAAFTRFDQDGNGVLDEKEQKE
TQQKLEGERVAVHAEIENLGWSIVRSPPGESSPKQAAKTGGWVSGEEFYTLTRRVLQLET
VLEGVMTQVDAMRSKLTMVERKGWLAPLPGAGEQGIWEHLQAAPAVTPAPWGL

>Gallus gallus_PKD2L1(ENSGALP_9247)
ESHFRSPEEHELEAVGKKVWDNPVYNGSPSTSLKIRTIYNPKSILENPYEGFEEVRDPVP
YQEEQNKTMEGKCCFYIFRGIRGPKGLWGTTLTENTAENRELYVKTTLRELLVYIVFLVD
ICLLTYGMTSSSAYYYTKVMSELFLQTSSDSRVSFQSIGSMADFWVYAQGPLLDNLYWTK
WYNNESLAAHNTQSYIYYENLLLGVPRMRQLKVKNNSCVVHDDFKEEISGCYDVYSEDKE
EKVSFGLINGTAWRYHSEEELGGSSHWGRLTSYSGGGYYIDLKLTREESAEALQILKEKL
WLDRGTRVVFIDFSVYNANINLFCVLRLVVEFPATGGAIPSWQIRTVKLIRYVSAWDFFI
VACEIVFCVFIFYYVVEEILELRIHRLQYFTSIWNILDVVVILLSIVAIGFHIFRTIEVN
RLLGELLKHPETYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLAR
CAKDILGFAIMFFIVFFAYAQLGYLLFGTQVENFSTFVKCIFTQFRIILGDFDYNSIDNA
NRVLGPVYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELSSQKDELQLSDILKQSYNRTL
MRLKLKKEQISDVQKALQNGTKELGFEDFKNSLKELGHADHEITAAFSRFDKDGNYVLDE
EEQQQMKHDLEAKRVALNTEIENLGKSYGGNNLDENLSYVEAKNNYANKASWVSKEEFQV
LLQRVLLLEQSIHSIGSKIDAVVSKLEVLERNKLETKDLMGKP

>Taeniopygia guttata_PKD2L1(ENSTGUP_7962)
GLWGTTLTENTAENRELYVKTTLRELLVYVMFLVDICLLTYGMTSSNAYYYTKVMSELFL
QTSADGRISFQSIGSMADFWVYAQGPLLDNLYWTKWYNNESLAAHSTQSYIYYENLLLGV
PRMRQLKVKNNSCVVHDDFKEEISGCYDVYSEDKEERISFGLINGTAWRYHSEEELGGSS
HWGRLTSYSGGGYYIDLKMTREESAEALQVLKEKLWLDRGTRVVFIDFSVYNANINLFCV
LRLVVEFPATGGAVPSWQIRTVKLIRYVTAWDFFIVACEIVFCVFIFYYVVEEALELRIH
KFQYFTSIWNILDVVVILLSIVAIGFHIFRTTEVNRLLGELLEHPNTYADFEFLAFWQTQ
YNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAIMFFIVFFAYAQLGYL
LFGTQVENFSTFVKCIFTQFRIILGDFDYNSIDNANRVLGPIYFVTYVFFVFFVLLNMFL
AIINDTYSEVKDELSSQKDELQLSDILKQSYNRTLMRLKLKKERISDVQKALQNGTKQLD
FEDFKNSLKELGHADHEITAAFSRFDKDGNHILDEEEQQQMKSDLEAKRQAIKYSSNSTC
MQLSIENLGKSYGDNNLDENLTYMEARNNHTNKATWVSKEEFQVLLHRVLQLEQSINSIG
SKIDAVVNKLDVPERKELRRKDLLGKPL

>Danio rerio_PKD2L1(ENSDARP_119061)
MESFGHGGWVNQAFSGSPAAVRRPVSTIYSPQPGFHSPLENPYLNQDKARTMPNEDKKSG
CCSFFFRAIKGLWGTALRKDTKENPELNVKANLKELLIYIVFLVDLCLLTYGMTSSATYY
YTKAMTDLFVNLPGSNGMSFSSIGCMNDVWTYMEGPLLDNLYWTKWYNDEPLENGNQSFI
YYENLLLGVPRVRQLKVKQNSCKVPTDFKKEISDCFDVYNIKKEDDGAFGLINGTAWQYH
SEKEIKGSSHWGLLTTYSGAGFYQDLTTTRDESAALLEDLRENLWLDRGTRVLFIDFTAY
NANINLFCVIRLVVEFPATGGAIPSYQIRTVKLIRYVTTWDYFIIGCEIVFCVFILYYIV
EEILEFRIHKLSHFTSIWNILDIVVILLAVVAIVFSAFRTIKVDGLLGNLLKQPDIYADF
EFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLTSTLARCALDIFGFAIMFFIVF
FAYAQLGYLLFGTEVETFSTFNKCIFTQFRIILGDFDYDAIDRANRVLGPIYFFSYVFFV
FFVLLNMFLAIINDTYSEVKSELASQKDEFQIADLIKQSYAKTFMKLKLKKEKISDVQKA
LDSGASELEFKDFRNALKEMGHSDREISAAFSKFDQDGNQTLDKQEQENMKQELEEKRDA
LSAELRDLENSVEPAEEHRNTVPPEDYQRLVHKVSQLENSVSAIMSKLDFVMEKMRLQTF
NTESRDMDKQTNRDDESRPASGGNIHVNLERVLAQGPSWSLTGPMGSARNRLYPDVGWPV
VTENNTSARH

>Takifugu rubripes_PKD2L1(ENSTRUP_46000)
SHLTGRVECEMEGVGNGAWVNCGFCDTPPPVPRVVSTIYNTQPHFQGSGDGMYKLDPLPT
FPEEPASAEQSLVKKRRGCCSFIKVVSSGLWGTTLTEDTSGNRELFVRTTLRELVVYLVF
LVDICLLTYGMTSSSTYYYTKAMTDLFVNAAGESGVKFQSISSMTDFWTYAQGPLLDGLY
WTKWYNNRSMNTGDQSFIYYENMLLGVPRMRQIKILNNSCNVHSDFRDEIAGCFDVYNEK
KEDYFNFGLINGTAWSYHTEKQIKGSSHWGLLTTYSGAGYYQDLRRTKEESAAILKDLLD
NLWLDRGTRVTFIDFSTYNANINMFCIIRLVVEFPATGGAIPSYQIRTVKLIRYISVWDY
FILGCETLFCLFILYYVVEEILELRIHKFSYFKSIWNILDIIVILLAIVAIIFNIFRTVK
VDNLLTKLLEQPDVYADFEFLAFWQTQYNNMNAVNLFFAWIKVFKYISINKTMTQLSSTL
GRCAKDILGFAIMFFIVFFAYAQLGYLLFGTEVESFSTFAKCIFTQFRIILGDFDYDAID
RANRVLGPIYFVTYVFFVFFVLLNMFLAIINDTYTEVKEELSSQKDELQITDIIKQSYMK
TIIKLKLKKEKISDVQKVLRSESGDIEFKDFRQTLKEMGHAEREISEAFSQFDRDGNQIL
DEEEQKRMKSELEEKRDALSAEINNLGVNYGKDSSVGATEQRNTWSQTFVDREQFLRLSR
QVFHLEHALEGVASRLELITEKLGLHE

>Tetraodon nigroviridis_PKD2L1(ENSTNIP_16073)
GLWSTTLTENTSNNRELFVRTTLRELVVYVFFLVDICLLTYGMTSSSTYYYTKAMTDLFV
NTADQSGLTFQSISTMADFWTYAQGPLLDGLYWTKWYNDQPLTTEDKSFIYYENMLLGVP
RMRQIKILNNSCKVHSDFKDEITGCFDVYNDKKEDYFNFGLINGTAWSYHTEKEIKGSSH
WGLLTTYSGAGYYQDLRRTKEESAAILKDLLDNLWLDRGTRVIFVDFSTYNANINMFCII
RLVVEFPATGGAIPSYQIRTVKLIRYISVWDYFILGCEVVFCLFIFYYIVEEILELRIHK
FSYFRSIWNILDIVVILLAVVAIIFNVFRTIKVDNLLGKLLEQPDIYADFEFLAFWQTQY
NNMNAVNLFFAWIKVFKYISFNKTMTQLSSTLGRCAKDIVGFAVMFFIVFFAYAQLGYLL
FGMEVESFSTFAKCIFTQFRIILGDFDYNAIDRANRVLGPIYFVTYVFFVFFVLLNMFLA
IINDTYTEVKEELSSQKDELQITDIIKQSYVKTIAKLKSKKEKISDVQKVLRSGSGDIEF
KDFKQTLKEMGHADHEISEAFSRFDRDGNQILDEEEQKRMKSDLEEKKDALSAEINNLGG
NYGNHSPVSGNEQRKNWSQTFVDREQFLRLARQVLHLERTLEGTTSRLDLIMEKLGLHE

>Gasterosteus aculeatus_PKD2L1(ENSGACP_4427)
ADSHLAPQVESDSMGNGAWVNHGYSGSPVPSPQGISTIYSSQPLFQGAVDSMYKLDTADP
FPEEPPSADPSPMKKKRGCCSFIKGFWGTTMTENTSNNRELFVRTTLRELVVYLVFLVDI
CLLTYGMTSSSTYYYTKAMTDLFVNTGGESGVSFQSIGTMADFWTYAQGPLLDGLYWTKW
YNNQSLNRGEQSFIYYENMLLGVPRMRQIKIMNNSCNVHKDFKDEITGCFDVYNDKKEDG
LSFGLINGTAWTYHTEKEVKGSSHWGLLTTYSGAGYYQDLSRTKDESAIILGELVDNLWL
DRGTRAAFLDFSAYNANINMFCVIRLVVEFPATGGAIPSYQIRTVKLIRYINYWDYFVLG
CEVVFCIFILYYVVEEILELRIHKLSYFNSIWNILDIVVIMLAIVAIIFNIFRTVKVDNL
LGKLLEQPGIYADFEFLAFWQTQYNNMNAVNLFFAWIKVFKYISFNKTMTQLSSTLGRCA
KDILGFAIMFFIVFFAYAQLGYLLFGTEVESFSTFVKCIFTQFRIILGDFDYDAIDRANR
VLGPIYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELSCQKDELQITDIIKQSYMKTFTK
LKLRREKISDVQKALQSGSGEIEFKDFRETLKEMGHADHEISAAFSRFDHDGNQILDKGE
QERMNIELEEKRDALCAELNHLGSHYGKDLMEKPAVTSNEQKHSSHMFVDQEQFQRLARQ
VLQLDSSVVGIQSNIELIMEKLRLQEERKG

>Oryzias latipes_PKD2L1(ENSORLP_17220)
SHLSGQVGSEPGAVGTGGWVNHGYCESPEPPGVSTIYGPRPAPQGPVDSPYSLDAAGKFP
EASVQRVKKKSGCCSFIKGRGLWGTALTENVSNNREKYIRTTLRELLVYLLFLLDICLLT
YGMTSSSTYYFTKAMTDLFVNSGGDAGVAFQSIGTMADFWSFAQGPLLDGLYWTKWYNQQ
SLNNGNQSFIYYENMLLGVPRMRQIKMKNNSCKVHQDFKDEIFGCYDVYDEKKEDDLNFG
LINGTAWTYHTEKEMRGSSHWGLLSTYSGAGYYQDLDRTRERSAEILSTLMDNCWLGRGT
RVVFIDFSAYNANINMFCVISLMVEFPATGGAVPSYQIRTVKLLRYVTRWDYFILGCEAV
FCVFILYYMVEEVLELRIHRFSYLKSVWNILDIVVILLALVAIAFNVFRTIKVDNLLGKL
LENPNIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSTTLGRCAKDIL
GFAVMFFIVFFAYAQLGYLLFGTEVDTFSTFVKCIFTQFRIILGDFNFDAIDQANRVLGP
IYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELTSQKDELQITDIIKQSYMKTFTRLKLK
KDKITDVQKALQAGSGEIQFKDFKQTLIEMGHTDGEISAAFSKFDRDGNQVLDAEEQERM
KRELQEKRDALSTELNHLGKNYEKEP

>Homo sapiens_PKD2L2(ENSP_424725)
MAEASRWHRGGASKHKLHYRKEVEITTTLQELLLYFIFLINLCILTFGMVNPHMYYLNKV
MSSLFLDTSVPGEERTNFKSIRSITDFWKFMEGPLLEGLYWDSWYNNQQLYNLKNSSRIY
YENILLGVPRVRQLKVRNNTCKVYSSFQSLMSECYGKYTSANEDLSNFGLQINTEWRYST
SNTNSPWHWGFLGVYRNGGYIFTLSKSKSETKNKFIDLRLNSWITRGTRVIFIDFSLYNA
NVNLFCIIRLVAEFPATGGILTSWQFYSVKLLRYVSYYDYFIASCEITFCIFLFVFTTQE
VKKIKEFKSAYFKSIWNWLELLLLLLCFVAVSFNTYYNVQIFLLLGQLLKSTEKYSDFYF
LACWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFFIIFFA
YAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANPILGPIYFITFIFFVFF
VLLNMFLAIINDTYSEVKADYSIGRRLDFELGKMIKQSYKNVLEKFRLKKAQKDEDKKTK
GSGDLAEQARREGFDENEIQNAEQMKKWKERLEKKYYSMEIQDDYQPVTQEEFRELFLYA
VELEKELHYINLKLNQVVRKVSAL

>Pan troglodytes_PKD2L2(ENSPTRP_48012)
MAEASRWHRGGASKHKLHYRKEVEITTTLQELLLYFIFLINLCILTFGMVNPHMYYLNKV
MSSLFLDTSVPGEERTNFKSIRSVTDFWKFMEGPLLEGLYWDSWYNNQQLYNLKNSSRIY
YENILLGVPRVRQLKVRNNTCKVYSSFQSLMSECYGKYTSANEDLSNFGLQINTEWRYST
SNTNSPWHWGFLGVYRNGGYIFTLSKSKSETKNKFIDLRLNSWITRGTRVIFIDFSLYNA
NVNLFCIIRLVAEFPATGGILTSWQFYSVKLLRYVSYYDYFIASCEITFCIFLFVFTTQE
VKKIKEFKSAYFKSIWNWLELLLLLLCFVAVSFNTYYNVQIFLLLGQLLKSTEKYSDFYF
LACWHIYYNNMIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCIKDIVGFAIMFFIIFFA
YAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANPILGPIYFITFIFFVFF
VLLNMFLAIINDTYSEVKADYSIGRRPDFELGKMIKQSYKNVLEKFRLKKAQKDEDKKTK
GSGDLAEQAGREGFDENEIQKAEQMKKWKERLEKKYYSMEIQDDYQPVTQGEFRDGTTTK
YKMRFSECLTK

>Gorilla gorilla_PKD2L2(ENSGGOP_10130)
MAEASRWHRGGASKHKLHYRKEVEITTTLQELLLYFIFLINLCILTFGMVNPHMYYLNKV
MSSLFLDTSVPGEERTNFKSIRSITDFWKFMEGPLLEGLYWDSWYNNHQLYNLKNSSRIY
YENILLGVPRVRQLKVRNNTCKVYSSFQSLMSECYGKYTSANEDLSNFGLQINTEWRYST
SNTNSPWHWGFLGVYRNGGYIFTLSKSKSETKNKFIDLRLNSWITRGTRVIFIDFSLYNA
NVNLFCIIRLVAEFPATGGILTSWQFYSVKLLRYVSYYDYFIASCEITFCIFLFVFTTQE
VKKIKEFKSAYFKSIWNWLELLLLLLCFVAVSFNTYYNVQIFLLLGQLLKSTETYSDFYF
LACWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLTRCIKDIVGFAIMFFIIFFA
YAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANPILGPIYFITFIFFVFF
VLLNMFLAIINDTYSEVKADYSIGRRPDFELGKMIKQSYKNVLEKFRLKKAQKDEDKKTK
GSGDLAEQARREGFDENEIQKAEQMKKWKERLEKKYYSMEIQDDYQPVTQEEFRELFLYA
VELEKELHYINLKLNQVVRKVSAL

>Mus musculus_PKD2L2(ENSMUSP_127257)
MSEATWWYRGGTSKHDLHYRREAEVNTTLEELLLYFIFLINLCILTFGMVNPHMYYLNKV
MSSLFVDTSLPDDERSSFRSIRSITEFWKFMEGPLIDGLYWDSWYGNKQLYSVKNSSRIY
YENVLLGIPRVRQLRVRNNTCKVYPAFQSLVSDCYSKYTVENEDFSDFGLKRNPEWTHTP
SSRTAPWHWGFVGVYRDGGYIVTLSKSKSETKAKFVDLRLNNWISRGTRAVFIDFSLYNA
NVNLFCIIRLLAEFPATGGLLTSWQFYSVKLLRYVSYYDYFIASCEVIFCIFLFVFIIQE
LRKVNEFKSAYFRSVWNWLEMLLLLLCFLAVSFYAYCNMQSFLLLGQLLKNTDSYPDFYF
LAYWHIYYNNVIAITIFFAWIKIFKFISFNETMSQLSSTLSRCMKDIVGFAIMFFIIFSA
YAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANWILGPIYFITFIFFVFF
VLLNMFLAIINDTYSEVKADYSIGRRPDFELGKIIQKSCFNVLEKLRLKKAQAKEEKKMQ
TTDLAQRARRDGFDESEIQEAEQMKRWKERLEKKYYSTEIQDDYQPVTQQEFRELFLYAV
ELEKELHYVSLKLNQLMRKLH

>Rattus norvegicus_PKD2L2(ENSRNOP_30483)
MSEATWWHRGGTSKHDLHYRREAEVNTTLEELLLYFIFLINLCILTFGTVNPHMYYLNKV
MSSLFVDTSLPDDERSSFRSIRSITEFWKFMEGPLVEGLYWDSWYGNTQLDSVKNSSLIY
YENILLGVPRVRQLRVRNSTCQVYPAFQSLASDCYNKYTAENEDFSDFGLKHDPEWRHSA
PSSTAPWHWGFVGVYRDGGYMVTLSKSKSETKAKLADLRQNNWIGRGTRAVFIDFSLYNA
NVNLFCIIRLLAEFPATGGILTSWQFYSVKLIRYVSYYDHFIASCEIIFCIFLLVFITQE
LRKLNEFKSAYFRSVWNWIELLLLVLCFLAVSFYAYCNVQCFLLLGQLLRSTESYPDFYF
LAYWHIYYNNIIAITIFFAWIKIFKFISFNETMSQLSSTLSRCMKDIVGFAIMFFIIFFA
YAQLAFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANWILGPIYFITFIFFVFF
VLLNMFLAIINDTYSEVKADYSIGRRPDFELGSIIKKSCFNILEKLRLRKAQNNEDKKMK
TSVDLAQARKEGFDESEIQEARQMKRWKERLEKKYYSTEIQDDYQPVTQQEFRELFLYAV
ELEKELHYLSLKLNQVMRKLH

>Canis familiaris_PKD2L2(ENSCAFP_1620)
MAEASRWHRGGTPKPKLHYRKEVEIRTTLQELALYFIFLINLCILTFGMVNPHMYYLNKV
MSSLFLDTSVPGDERTNFKSIRSITDFWKFMEGPLLEGLYWDSWYTNKTLYDLKNSSRIY
YENILLGVPRVRQLKVRNNTCKVYSSFQSLMNECYDKYTSKSEDMDEFGLKQETEWKYAA
PTSSSPWHWGFVGVYQNGGFIFTLSKSKSETKNKFVDLKLNSWITRGTRVIFIDFSLYNA
NVNLFCIIRLAAEFPATGGIITSWQFYSVKLLRYVSYYDYIIASCEITFCIFLIVFTTQE
AQKIREFKSAYFKSVWNWLELLLLVLCFVTVTFNIYCNVQIFLLLGDLLKNTEKYSDFYF
LAYWHTYYNNVIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCLKDIVGFAIMFFIIFFA
YAQLGFLVFGSQVDDFSTFQNAIFAQFRIVLGDFNFAGIQQANRILGPIYFITFIFFVFF
VLLNMFLAIINDTYSEVKADYSIGRRPDFELGKMIKKSYNNALEKLRLKKPEQDEDISMK
GDLAEQARREGFDENEIQSAEQMKKWKDRLEKKYYSTEIQDDYQPVTQQEFRELFLYAVE
LEKELHYVSLKLNRVMRKLS

>Felis catus_PKD2L2(ENSFCAP_14420)
MAEASRWHRGGAPKPKLHYRKEVEIRTTLQELSLYFIFLINLCILTFGMVNPHMYYLNKV
MSSLFLDTSVPGDERTNFKSIRSITDFWKFMEGPLLEGLYWDAWYTNKTLYNLKNSSRIY
YENILLGVPRVRQLRVRNNTCKVYSSFQSLMSECYDKYTSSNEDTSDFGLKQETEWKYST
PNSSSPWHWGFVGVYRNGGFIFTLSKSKSDTKKFINLQLDSWITRGTRVIFIDFSLYNAN
VNLFCIIRLVAEFPATGGIITSWQFYSVKLLRYVSHYDYIIASCEITFCIFLIVFTTQEA
QKIREFKSAYFKSVWNWLELLLLVLCFVAVSFNIYCNIQIFLLLEDLLKNTEKYSDFYFL
AYWYIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSTTLSRCLKDIVGFAIMFFIIFFAY
AQLGFLVFGSQVDDFSTFQNAIFAQFRIVLGDFNFAGIQQANRILGPIYFITFIFFVFFV
LLNMFLAIINDTYSEVKADYSIGRRPDFELGEMIKKSYNNALEKLRLKKPQKDEDDKGIK
GDLAEQARREGFDENEIQSAEQMKKWKERLEKKYYSSEIQDDYQPVTQQEFRELFLYAVE
LEKELHYISLKLNRVMRRISALQN

>Bos taurus_PKD2L2(ENSBTAP_10236)
MAEASRWHLGGTPKHKLHYREDVEIRTTLQELLLYSIFLINLCISGEERTNFKSIRSITD
FWKFMEGPLLDGLYWDSWYNNENLYDLKNSSRIYYENILLGLPRVRQLKVRNGTCKVHSF
FRSLMDECYDKYTSKNEDTADFGLKQHTEWKYSSPRTNSPWHWGFVGVYQNGGYIFTLSK
SKSETLNKFINLRMNSWITRGTRVIFIDFSVYNANVNLFCIIRLVAEFPATGGILTSWQF
YSVKLLRYVSFYDYFIASCEIIFCIFIIVFTIQEIKKLKEFKFAYFKSIWNWLELLLLVL
CFSTVFFSLYSNMQIYRMIGRLLRNTEKYSDFYFLAYWHIYYNNIIAITIFFAWIKIFKF
ISFNKTMSQLSSTLSRCIKDIIGFAIMFFIIFFAYAQLGFLVFGSQVDDFSTFQNAIFTQ
FRIVLGDFNFAGIQQANRILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRR
PDFQLGKMIKKSYNNALEKLKLKKPETDEDKKRMENKDLAEKARREGFDEKEIQSAEQMK
KWKERLEKKYYSTEIQDDYQTVTQQEFRDLFLYAVELEKELHYVSLKLNRVMRKVSALQY

>Monodelphis domestica_PKD2L2(ENSMODP_15351)
MGIGLSHRERTQARGLALGWVWLEAEELLRGGEGRVRARQFKRHQKHPPPSRPHELKPVM
AKVRSLRSKKRHMKDIVALKTEKISKKAEIKTNLQELIIYFIFLTDLCILTFGMVSTNIY
YLNKIMSTLFLETSVPGEDRTNFKSISTTEEFWKFMEGPLLDGLFFDYGYNTETLDQMKS
SRIYHENILLGVPQIRQLKVRNNTCIVYSKFKSLMDECFDRYTIGNEDQSDFGRGEVPEW
TYSRATSKSFQHRGLVGVYNDGGYRFTLPLSKTDAKSKFSFLQANNWITRGTRAVFIDFS
VYNANVNLFCIIRLVAEFPATGGVLTSWTFNSVKLLRYVSYFDYFIASCEIIFCIFIITF
IIQEIKKIKEHKYAYFKSIWNLLELLLLVLSFLAISVNILRTSKATLLLGHLLGKNKEYA
DFYFLAFWQILYNDIIAINIFFAWIKIFKFISFNETMSQLSTTLSRCIKDIIAFAIMFFI
IFFAYAQLGYLVFGSQVDDFSTFQNSVFTQFRIVLGDFNFANIEKANWVLGPAYFITFIF
FVFFVLLNMFLAIINDAYSEVKADYSIGRMPRSALADQIKAGYTKTVEKLKLKKTPKKPK
SEVKKKAEAVQTRRGFDQDTLLIFTGTREGIALCQYKIKQSDEKDNCNTNMRCASKGL

>Anolis carolinensis_PKD2L2(ENSACAP_16802)
LLMFLEIPHTGSIRPRLTHSRELEMKTSLQELLIYIIFLTDLCILTFGMVSTDMYYLNKV
MSNLFLETPLSDTDKTDFTTMGSISDYWEFLEGPLLDGLFWNTWYNTNSTSIHRNSSHIY
YENLLLGVPQIRQLKIRNNTCSIYPSFRAFMKVCYGQYRYLYEDRESFGLKNDTEWFYSS
SQTLTPWHWGLIGLYGSGGFMFTLPKSKEKSLEKLIYLKENSWITRGTRAVFIDFSMYNA
NVNLFCIVRRIYGEFPATGGAIPSWQFHSVKLLRYVSYYDYFLASCEVIFCLFIVAFIIQ
EITKMKKLKKEYFRDAWNWLDMLLILLSVFAIAFNVYRTVEVSELMEKLLSNSESYPDFY
FLGFWQTRYNNMISVNVFFAWIKIFKFISFNKTMTQLSSTLSRCAKDIIGFAIMFFIIFF
AYAQLGYLVFGSQVDEFSTFQNCIFTQFRIVLGDFNFASIEHANRILGPIYFITFVFFVF
FVLLNMFLAIINDTYSEVKADFSVIPSREFEISDLIRQSYNKALVKLRLKRQTSQTEDVY
SIKSGPLGFSLTQYGLNSLSATLLCNHNNYIATLYKLYNVLRVPDPVSHKEFQKLSKYIA
DLEKQLKDVTLKLNEVTKSIPKASPERLKQRS

>Pelodiscus sinensis_PKD2L2(ENSPSIP_15795)
YSRELEMKTTLQELLIYIIFLTDLCILTFGMVNTDMYYLNKVMSNLFLDTSVSETDRISF
KTIGSMVDFWKFAEGPLLDGLYWDTWYNNKTLTSHKNSSHVYYENLLLGLAQIRQLKVRN
NTCSIYPYKCYHEYRYGAEDRSDFGLKNGSVWSYSSASSLAPWHWGAIGLYSGGGFMFTL
PKSKSESIRKLAFLRRNGWITRGTRVIFIDFSVYNANINLFCVVRLVVEFPATGGALPSS
QFYSVKLLRYVTYYDYFLASCEVIFCLFIFAFIIQEIMKVRKLKTEYFKSAWNWLDMLLV
SLSIFAIAFNMYRTVEVSMLMESLLSNAYAYPDFYFLAYWQTRYNNMIAINVFFAWIKIF
KYISFNKTMTQLSSTLSRCAKDIIGFAIMFFIIFFAYAQLGYLVFGSQVDEFSTFQNCIF
TQFRIVLGDFNFASIEQANRILGPIYFITFVFFVFFVLLNMFLAIINDTYSEVKADFAVI
PSKEFEISDLIRQSYNKALVKLKLKKSKMEDLYPAGGSLQTLSSAGQGYLKSPQLQKWKE
KLHQKYHSAEDKESAAAPQDHVSPQEFQQLFRYATDLETRLNEVNAKLSRVLRNM

>Homo sapiens_PKDREJ(ENSP_253255)
MRPGPALLLLGVGLSLSVGRLPLPPVPRGAQAAVSGAPGGLLRGAPGLGVRGGRALLSLR
PSAVRAGGAVLSGRGSLCFPHGGTGRRWYCLDLRVLLSAQRLPWPAAPALALVDLQLSAR
GGRLSLTWSVRLPRSPGRLAWAFRLRLLGPGAARPASPAARVSPRSAAPGPRPQQGFVAR
TECPTDGPARVMLQAVNSSSHRAVESSVSCQINACVIQRVRINTDQKGAPVRLSMQAEAT
INASVQLDCPAARAIAQYWQVFSVPAVGQAPDWTQPLDLPQLEIRNSPLFIHIPNNSLQW
GVYVFNFTVSITTGNPKMPEVKDSDAVYVWIVRSSLQAVMLGDANITANFTEQLILDGST
SSDPDADSPLQGLQFFWYCTTDPRNYGGDRIILGSKEVCHPEQANLKWPWASGPVLTLLP
ETLKGDHVYFFRMVIRKDSRTAFSDKRVHVLQGPKAIAHITCIENCERNFIVSDRFSLFL
NCTNCASRDFYKWSILSSSGGEMLFDWMGETVTGRNGAYLSIKAFAFRHFLEAEFSISLY
LACWSGVTSVFRHSFIINHGPQIGECKINPAKGIALITKFVVQCSNFRDKHVPLTYKIIV
SDLHSVGEISSVKENTLGTILYLGPQSTVPPSFLPVGMLASQYGLKIYAQVYDSLGAFSQ
VTLHATAQAPTDKNSSKTVLNQLLSFTVGPSSLLSTLIQKKDFLPAGYLLYIVASVLNNM
KTELPLRDDRVNLRKHLIDQSFLLPVSTLVEIGQVVMTITKLTQKPSEFTWDAQKRATMR
VWQANQALQEYQQKDKRFRSEQIEIVSTGILMSLSNILKMTSPHQVVKDPFYVIESLSDT
ILANKVPGNKTTSMRTPNFNMYVKKVEKWGINQLFRNEKHCRNCFYPTLNVSSVPGLSAN
GPISTMFCDFTNDLFPWLNDQENTSVEVSGFRMTGVADNGSVLEITPDVAEVYLVRKNLT
FAAFNLTVGPNSEVDGSLKKTTGGFSFQVDSTVLREVLVHIVTEVMVLFTVLVYTGSQIT
PTALVATFLVPHDIPPFASQSALFDPACTVKKARVVCLPVSLLQLIAQHSHSPHCTVSIV
LQAPRFVMKLNDKLVRISIFSVQCLDMYGIQSEWREGYCILGEKTSWYEVHCICKNVVRA
RRQLGTIGLTGIHLHTHYVMAKVIVIPNPVDLRLNIIKSLHQNPVTLFTVLFIILLYVGL
AFWALYRDEMDQHLRGHVIVLPDNDPYDNLCYLVTIFTGSRWGSGTRANVFVQLRGTVST
SDVHCLSHPHFTTLYRGSINTFLLTTKSDLGDIHSIRVWHNNEGRSPSWYLSRIKVENLF
SRHIWLFICQKWLSVDTTLDRTFHVTHPDERLTRKDFFFIDVSSNLRKNHMWFSIFASVV
AKTFNRLQRLSCCLAMLLSSLLCNIMFFNLNRQEQTESRERKYMRSMMIGIESVLITIPV
QLLITFLFTCSQRKPQADLKEVSPQKHPLMSEASEHWEEYLRKWHAYETAKVHPREVAKP
ASKGKPRLPKASPKATSKPKHRHRKAQIKTPETLGPNTNSNNNIEDDQDVHSEQHPSQKD
LQQLKKKPRIVLPWWCVYVAWFLVFATSSISSFFIVFYGLTYGYDKSIEWLFASFCSFCQ
SVLLVQPSKIILLSGFRTNKPKYCKNLSWSTKYKYTEIRLDGMRMHPEEMQRIHDQIVRI
RGTRMYQPLTEDEIRIFKRKKRIKRRALLFLSYILTHFIFLALLLILIVLLRHTDCFYYN
QFIRDRFSMDLATVTKLEDIYRWLNSVLLPLLHNDLNPTFLPESSSKILGLPLMRQVRAK
SSEKMCLPAEKFVQNSIRREIHCHPKYGIDPEDTKNYSGFWNEVDKQAIDESTNGFTYKP
QGTQWLYYSYGLLHTYGSGGYALYFFPEQQRFNSTLRLKELQESNWLDEKTWAVVLELTT
FNPDINLFCSISVIFEVSQLGVVNTSISLHSFSLADFDRKASAEIYLYVAILIFFLAYVV
DEGCIIMQERASYVRSVYNLLNFALKCIFTVLIVLFLRKHFLATGIIRFYLSNPEDFIPF
HAVSQVDHIMRIILGFLLFLTILKTLRYSRFFYDVRLAQRAIQAALPGICHMAFVVSVYF
FVYMAFGYLVFGQHEWNYSNLIHSTQTVFSYCVSAFQNTEFSNNRILGVLFLSSFMLVMI
CVLINLFQAVILSAYEEMKQPVYEEPSDEVEAMTYLCRKLRTMFSFLTSQSKAKDEPEFF
IDMLYGQPEKNSHRYLGLKTRNINGKKMVYLVV

>Pan troglodytes_PKDREJ(ENSPTRP_25004)
MSPGPALLLLGVGLSLSVGRLPLPPAPRGAQAAVSGAPGGLLRGAPGLGVHSSRVRLPRS
PGRLAWAFRLRLLGPGAARPASPAARVSPRSAAPGPRPQQGFVARTECPTDGPARVMLQA
VNSSSHRAVESSVSCQINACVIQRVRINTDQKGAPVRLSMKAEATINASVQLDCPAARAI
AQYWQVFSVPAVGQAPDWTQPLDLPQLEIRNSPLFIHIPSNSLQWGVYVFNFTVSITTGN
PKMPEVKDSDAVYVWIVRSSLQAVMLGDANITANFTEQLILDGSTSSDPDADSPLQGLQF
FWYCTTDPRNYRGDRINLGSKEVCHPEQANLKWPWASGPVLTLLPETLKGDHVYFFRMVI
RKDSRTAFSDKRVHVLQGPKAIAHITCIENCERNFIVSDRFSLFLNCTNCASRDFYKWSI
LSSSGGEMLFDWMGETVTGRNGAYLSIKAFAFRHFLEAEFSISLYLACWSGVTSVFRHSF
IINHGPQIGECKINPAKGIALITKFVVQCSNFRDKHVPLTYKIIVSDLHSVGEISSVKEN
TLGTILYLGPQSTAPPSFLPVGTLASQYGLKIYAQVYDSLGAFSQVTLHATAQAPTDKNS
SKTVLNQLLSFTVGPSSLLSTLIQKQDFLPAGYLLYIVASVLNNMKTELPLQDDRVNLRK
HLIDQSFLLPVSTLVEIGQVVMTITKLTQKPSEFTWDAKRATMRVWQAQALQEYQQDNRF
RSEQEVSTGILMSLSNILKMTSPHQVVKDPFYVIESLSDTILANKVPGNKTTSMRTPNFN
MYVKKVEKWGINQLFRNEKHCRNCFYPTLNVSSVPGLSANGPVSTMFCDFTNDPFPWLND
QENTSVEVSGFRMTGVADNGSVLEITPDVVEVYLVRKNLTFAAFNLTVGPNSEVDGSLKK
TTGGFSFQVDSTVLREVLVHIVTEVMVLFTVLVYTGSQITPTALVATFLVPHDIPPVASQ
SALFDPACTVKKARVVCLPVSLLQLIAQHSHSPHCTVSVVLQAPRFVMKLNDKLVRISIF
SVQCLDMYGIQSEWREGYCILGEKTSWHEVHCICKKVVRARRQLGTIGLTGIHLHTHYVM
AKVIVIPNPVDLRLNIIKSLHQNPVTLFTVLFIILLYVGLAFWALYRDEMDQHLRGHVIV
LPDNDPYDNLCYLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHFTTLYRGSIN
TFLLTTKSDLGDIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQKWLSVDTTLD
RTFHVTHPDEPLTRKDFFFIDVSSNLRKNHMWFSIFASVVAKTFNRLQRLSCCLAMLLSS
LLCNIMFFNLNRQEQTESRERKYMRSMMIGIESVLITIPVQLLITFLFTCSQRKPQADLN
EVSPQKHPLMSEASEHWEEYLRKWHAYETAKVHPREVAKPASKGKPRLPKASPKATSKPK
HRHRKAQIKTPETLGPNTNSNNNIEDDQDVHSEQHPSQKDLQQLKKKPRIVLPWWCVYVA
WFLVFATSSISSFFIVFYGLTYGYDKSIEWLFASFCSFCQSVLLVQPSKIILLSGFRTNK
PKYCKNLSWSTEYKYTIVLLRHTDCFYYNQFIRDRFSMDLATVTKLEDIYRWLNSVLLPL
LHNDLNPTFLPESSSKILGLPLMRQVRAKSSEKMCLPAEKFVQNSIRREIHCHPKYGIDP
EDTKNYSGFWNEVDKQAIDESTNGFTYKPQGTQWLYYSYGLLHTYGSGGYALYFFPEQQR
FNSTRRLKELQESNWLDEKTWAVVLELTTFNPDINLFCSISVIFEVSQLGVVNTSVSLHS
FSLADFDRKASAEIYLYVAILIFFLAYVVDEGCIIMQERASYVRSVYNLLNFALKCIFTV
LIVLFLRKHFLATGIIRFYLSNPEDFIPFHAVSQVDHIMRIILGFLLFLTILKTLRYSRF
FYDVRLAQRAIQAALPGICHMAFVVSVYFFVYIAFGYLVFGQHEWNYSNLIHSTQTVFSY
CVSAFQNTEFSNNRILGVLFLSSFMLVMICVLINLFQAVILSAHEGMKQPVYEEPSDEVE
AMTYLCRKLRTMFSFLTSQSKAKDEPEFFIDMLYGQPEKNSHRYLGLKTRNINGKKMVYL
VV

>Gorilla gorilla_PKDREJ(ENSGGOP_26952)
MRPGPALLLLGLGLSLSVGRLPLPPAPRGAQAAVSGAPGGLLRGAPGLGVRGGLLGPGAA
RPASPAARVSPRSAAPGPRPQQGFVARTECPTDGPARVMLQAVNSSSHRAVESSVSCQIN
ACVIQRVRINTDQKGAPVRLSMKAEATINASVQLDCPAARAIAQYWQVFSVPAVGQAPDW
TQPLDLPQLEIRNSPLFIHIPSNSLQWGVYVFNFTVSITTGNPKMPEVKDSDAVYVWIVR
SSLQAVMLGDANITANFTEQLILDGSTSSDPDADSPLQGLQFFWYCTTDPRNYRGDRIIL
GSKEVCHPEQANLKWPWASGPVLTLLPETLKGDHVYFFRMVIRKDSRTAFSDKRVHVLQG
PKATAHITCIENCERNFIVSDRFSLFLNCTNCASRDFYKWSILSSSGGEMLFDWMAETVT
GRNGAYLSIKAFAFRHFLEAEFSISLYLACWSGVTSVFRHSFIINHGPQIGECKINPAKG
IALITKFVVQCSNFRDKHVPLTYKIIVSDLHSVGEISSVKENTLGTILYLGPQSTVPPSF
LPVGTLASQYGLKIYAQVYDSLGAFSQVTLHATAQAPTDKNSSKTVLNQLLSFTVGPSSL
LSTLIQKQDFLPAGYLLYIVASVLNNMKTELPLQDDRVNLRKHLIDQSFLLPVSTLVEIG
QVVMTITKLTQKPSEFTWDAQKRATMRVWQANQALQEYQQKDKHFRSEQIEIVSTGILMS
LSNILKMTSPHQVVKDPFYVIESLSDTILANKVPGNKTTSMRTPNFNMYVKKVEKWGINQ
LFRNEKHCRNCFYPTLNVSSVPGLSANGPISTMFCDFTNDTFPWLNDQENTSVEVSGFRM
TGVADNGSVLEITPDVAEVYLVRKNLTFAAFNLTVGPSREVDGSLKKTTGGFSFQVDSTV
LREVLVHIVTEVMVLFTVLVYTGSQITPTALVATFLVPHDIPPVASQSALFDPACTVKKA
RVVCLPVSLLQLIAQHSHSPHCTVSIVLQAPRFVMKLNDKLVRISIFSVQCLDMYGIQSE
WREGYCILGEKTSWHEVHCICKKVVRARRQLGTIGLTGIHLHTHYVMAKVIVIPNPVDLR
LNIIKSLHQNPVTLFTVLFIILLYVGLAFWALYRDEMDQHLRGHVIVLPDNDPYDNLCYL
VTIFTGSRWGSGTRANVFVQLRGTVSASDVHCLSHPHFTTLYRGSINTFLLTTKSDLGDI
HSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQKWLSVDTTLDRTFHVTHPDEPLT
RKAFFFIDVSSNLQKNHMWFSIFASVVAKTFNRLQRLSCCLAMLLSSLLCNIMFFNLNRQ
EETESRERKYMRSMMIGIESVLITIPVQLLITFLFTCSQRKPQADLKEVSPQKHPLMSEA
SEHWEEYLRKWHAYETAKVHPREAAKPASKGKPRLPKASPKATSKPKHRHRKAQIKTPET
LGPNTNSNNNIEDDQDVHSEQHPSQKDLQQLKKKPRIVLPWWCVYVAWFLVFATSSISSF
FIVFYGLTYGYDKSIEWLFASFCSFCQSVLLVQPSKIILLSGFRTNKPKYCKNLSWSTKY
KYTEIRLDEMRMHPEEMQRIHDQIVRIRGTRMYQPLTEDEIRIFKRKKRIKRRALLFLSY
FLTHFIFLVLLLILIVLLRHTDCFYYNQFIRDRFSMDLATVTKLEDIYRWLNSVLLPLLH
NDLNPTFLPESSSKILGLPLMRQVRAKSSDKMCLPAEKFVQNSIRREIHCHPKYGIDPED
TKNYSGFWNEFDKQAIDESTNGFTYKPQGKQWLYYSYGLLHTYGSGGYALYFFPEQQRFN
STLRLKELQESNWLDEKTWAVVLELTTFNPDINLFCSISVIFEVSQLGVVNTSISLHSFS
LADFDRKASAEIYLYVAILIFFLAYIVDEGCIIMQERASYVRSVYNLLNFALKCIFTVLI
VLFLRKHFLATGIIRFYLSNPEDFIPFHAVSQVDHIMRIILGFLLFLTILKTLRYSRFFY
DVRLAQRAIQAALPGICHVAFVVSVYFFVYMAFGYLVFGQHEWNYSNLIHSTQTVFSYCV
SAFQNTEFSNNRILGVLFLSSFMLVMICVLINLFQAVILSAYEEMKQPVYEEPSDEVEAM
TYLCRKLRTMFSFLTLQSKAKDEPEFFIDMLYGQPEKNSHRYLGLKTRNINGKKTVYLVV

>Callithrix jacchus_PKDREJ(ENSCJAP_294)
VRASGVVLSGGGRSLPSPAEGAGRRWYCCLDLRVLLSTQRPPQPAAPTPVDLQLSARRGR
LSLTWSAPLPRPPGSPAWTFLMRLLGPVVARTECPTDGPARVVWQAVNSSRHRAVESSVS
CQIDACVIQSVRINTDRRGAPVRLSRTAETTLNAKQLDCPGALAISQYWQVFSVPAVGHA
PDWTQPLDLPQLEIRRSPLFIHIPSHSLYWGVYVFNFTVSIVTGNPKMSEVKDSDAVYVW
ITRSPLQAVMLGEAHITANFPERLILDGSTSSDPDADSPLQGLQFLWYCTTDPRNYRGDQ
IILGSKDVCHPEQANLKWPWASGPVLTLPPETLKGDQVYFFRMVIRKDSRTAFSDKRVHV
LQGPEAIAHLTCMENCERTLAVSDRFALFLNCTNCASRDVYRWSLLSSSGGEMLFDWSGE
TVTGRHGAYLSVKAFAFRYFLEAEFWISLHLASWTGTTSVFRHSFIINHGPQIGECKINP
AKGIALMTKFVVQCSNFRDKHMPLTYKIIVSDVHGAGEISSVKENTLGTILYWGLSPQTP
SFLPVGMLANQYASKIYAQVYDALGAFSQVTLYATAQAPTNKNSSKTVLNQLLSFTMGPS
SLLSTLIQKQDFLPAGYLMYVVASVLNNMRTEFSLQDDRVSLREHLVEQSFLLPASTLVE
IGQVVMAVTKLTQKPSEFTWDAQKRVTMRTWQANHALQEYQQKDQHFRSEQIEIVSTGIL
MTMSNILNLTSSNQAMKDPFCVLESLSDTILANKVPGNETTSMRTPNFNMYVKKVEKWDV
TQVFRDEKHCRNCFYPTLNASSVPGLSANAPISTMFCDFTNDPFPWLNDQENTSFVISGF
RMTGVADNGSVLEITPDVAEVFLVRKNVAFAAFDLTVGPDREVDGSSKTTGGFSFQVDSR
VPREVLVHIVTEVTVPFTVLVYTGSQITPTALVATFLVPHDIPPVASQSALFDPACKVKK
ARVVCLPLSLLQLIAQHSHSPFCAVSIVLQAPRFVMKPSDKLVRISLFSVQCLDMYGIQS
EWREGYCILGEKTSWHEVHCVCKNLVRARRQLGTLGLASIHLHTHYVMAKVLVIPNPVDL
RLNIIETLYQNPVTLLTVLFVILLYMILAFWTLYRDEMDQFLRGHVIVLPDNDPYDNLCY
LVTVFTGSRGGSGTRANVFVQLRGTVSTSDVHCLSHPHFTALHRGSISTFLLTTKGDLGD
IHSFSRHVWLFICQKWLSIDTTLDRFQVTHPDEPLTRKDFFFIDVSSKLQKNHMWFSVFA
GGVAKTFSRLQRLSCCLATLLSSLLCNIMFFNLNKQQTESRERKYIRSMMIGIESVFITI
PVQLLITFLFTCSQRKPHADLKEASPQKLPLMAEGSGHWEESLRTWHANETAKELPREAA
KGTPEPRLLKAAPKATPEPKHRHRKAQIKTPETRRPNTNSNNNEDDLNVPSEEHSSQQEL
WQLKKKAQIVLPWWCVYVAWFLAFATSSISSFFIVFYGLTYGYDKSMEWLFASFCSFCQS
VFLVQPCKIILLSGFRTNKPKYCKNLSWSTMYQYTEIRLGGMSKHPDERQRIHDQIVRIR
GTNMYRPLTEDEIRIFKRKKRISRRALLLLSSILTHFIFLALLLVLVMLLYHTDTFYYNQ
FIRDRFSVDLATVTNLEDIYRWLHSVLLPLLHNDLNPTFLPESSSKILGLPLMRQVRAKS
SGKMCLPAEKFVQSSIRREIHCHPTYGIDPEDTKNYSGFWNGVDQQAVDESISGFTYKPQ
GKQWLYYSYGLLHTYGSGGYAFYFFPEQQRFNSTLRLRGLQESNWLDEKTWAVLLELTTF
NPDVNLLCSISVMFEVSQLGVVNTSVSLHSFSLADFDRNSAQIYLYLAFSFLSFFHFPMR
LYYSSTCEYLLNLPLNCLFTELLPLLRKLFLXHVMRIILGFLLFLTILTLRYSRFFYDVR
LAQRAIQAALPGICHMAFAVSVYFFAYTAFGYLVFGQHEWNYSNLIHSTQTVFSYCVSAF
QNTDFSNNRILGVLFLWSFVLVMICILINLFQAVILSAYEEMKQPVYEEPSEEVEAMTYL
CRKLRTIFSFLTSRSKAKDEPEFFTDMMYGQPEKNSRRFLGLKTRNINGKKMVYLVV

>Mus musculus_PKDREJ(ENSMUSP_86352)
MWPGPALLLLGLGLGLGSQPPPTGPRGLPGVLRGAPGLGQGAESSVRGGDTGGLSPRAAP
RHASPTPPRRCPSGAAARVLLKVNSSDPAAAKANVSCQTAPCIMQPVKINRKDQNAPLIL
SRDEEATLNITVRWYCPDALVIRKSWVYFSVASVNDTPDWNRPVLLPQVAVSKGFSLHIP
KYALPYGVYVFNFTLSIFRWDLAWPTVTGSDIIYIWVRKRPLKAVLLGAPRVTVKFSDEL
ILNGSMSYDPEADIPTWGLQFFWYCTTNPRYYSGNYVLVINQAVCHPEQDSLNWPWAVGS
VLTIPPKTLRGNGVYYFRMVVQKQNRTAFSDKTVHVLQGLQPKAHISCIENCGPTLGVSD
RFSLFLNCPSCGRQDLYSWSILSLTGHEVMFDWAGQAITRRNGPYLSIKAFAFRNFLENR
VWVSLILKSWSGMTTTLRHPVVINHGPRVGKCKINPASGISMVTKFAVECSDFKDENLPL
KYKIIVSELDSIGAISSVEENTLGSVVYSGAEPITPAFFLPVGTVTDEYNVRLYVQVYDS
LGTFSQVTLQATVTAPTVRDSSKDVLQQLLNVTMKPTSLLSTLLQKQDWLQAGYLTYVVI
SVLNNIKGEQELQDDRARLLEHLVKQSLTFAMNTADEIGQSVMVITKLTQKASDLSQADL
EATSFRLRQASQDLQEYQHRHKHLQQVEVVGTGILTSLSNLLKLINPYYTLQDPLFVVES
LSDTILANKVPGSKTTALRTSNFNMYVEKVENWNVFKAFRNDSLCPNCLRATLNASTVPR
LPAKAPISMMFCEFADDPFPWLTYPENISVDVVGFRMTGVADNNKVIEITPDIAEVYLVR
KDLTPSSFNLTVGPGIKSDGFSKVTTGGISFEVDSRWTGELLIHIVTNVTVLFEALVYEG
CQLTPTNLMATFLVPNDIPPIVKWSGLFDPTCSVKEARVVCLSSSLLRSIAQRRFSFKYN
ISMVLQASRFVLKPTNKLVRIALFMVHCLDMYGIQSDWQQSTCVLGEKTTWKTVHCVCRN
GRRSRRQLTSVKLTYHHLHTHFVTAKVIVVPNPVDLRLAIISNLTQNPATFLAVLFIMIL
YAILAFWALHRDVIDLYFRDNVVILTDNDPFDTLCYLVTIFTGSRWGSGTRANVFIQLMG
TEGTSDVHCLSHPYFKTLYRGSINTFLLTTKNDLGDIHSIRVWHDNSGEAPSWYLSRIKV
ENLFNKRIWLFVCRRWLSVDTTLDATFSVTNPDEPLKRTDFFMIDVRDKLRKNHMWISIF
TEIVPKPFNRLQRLSCCLAMLLSSLVCNIMFFNLNQKEKIESRHMHIIRSMLIGIESVVI
TIPVQLLITFFFTYSQKNLKMNLDKVAPQKHPLMSEEGLSWKERLHKWHEYEMKALPRRA
AVSTSAPEEKEAFETSQKHEKADTQMSNKNSSNNNQEASEGVPPKAFSSQPHTTESVQKK
TQIILPRWCVYIAWFLVFATSGISSFFIVFYGVTYGYAKSIEWLFASFCSFCQSVFLVQP
CNILLRSGTRSYKPKYCKNLSWSSKYHYSEIRLQGLTMTQEEMEQLHEDIAYVRSLSMYQ
PITEDKIQILRRENRIRRRSFLFLSYLVTHFIFLTLLLLLIFSLRHNDSFYYNQFIRHRF
SVDLATVMKLGDIYTWLHGVFLPLLHNDPNPTFLPDSSSKILGLPLVRQVRARPSNKTCL
LAKKFVQSSVAGEIHCHPQYGIDPEDTQHYSSVWSKAGKQSTDKASHGFTYKPPGKRWVY
HSYGVLNTYGSGGYVFYFFPGQQMFNSTVRLKELEGKNWLDELTWAVIVELTTLNPDTSL
MCSISVVFEVSPLGVVNSSLSVYSFSLADFNRKTSSEIYLYAAILIFFCAYVVDEGYIIR
QERASYIRSVYNLLNFSLKCMFALLIVLFFWKYFLATKMVQLYLADPEAFIPFHAVSRVD
HFMRIILAFLLFLTILKTLRYSRFFYNVRLAQKAIQAALPGICHTALVVSIYSFMYVAFG
YLVFGQHEWNYSNMIHATQTIFSYCVSAFQNTEFSGNKVLGVLFLSSFMLVMICIFINLF
QAVILSAYDEMKQPVYEEPSDEAEAVTYLCNRLKSGFDFLTTRSRDKDQSNFFVDMLYGQ
PEKNTRRFLGLKARNINGKKMIYLVV

>Rattus norvegicus_PKDREJ(ENSRNOP_48039)
MWPGPALLLLGLGLGLGSQPPPPGPRGLPGVLRGAPGLGQGAESSVRGGGTGGLSPRSVP
RRASPTLPRRCPSGAAARVLLKVNSFDPAAAKATVSCQTANCIIQPVKIINRKDQNAPLI
LSRDQEVTLNVTIRWHCPDALVVRKTWLYFSVASVNDTPDWNRPVQLPHVQVTKVSFLHI
PKYALPYGVYVFNFTLSLVRWDPVLPTVTDSDIIYIWVKKRPLKAVLPGASRVTVRFSDA
LILNGSMSYDPEADIPTEGLIFFWYCTTNPRYYSDNYMLVTNRDVCHPKQDSLDWPWAVG
PVLTIPAETLRGNGVYYFRMVVQKQNRTAFSDKTVHVLQGLQPKAHISCIENCGHTLAVS
DRFSLFLNCSSCGSRDFYSWSILSRMGKEVMFDWAGQAVTRRDGAYLSMKAFAFRDFLEN
RFWVSLILKSWSGVIMTLRHPVVINQGPQVGKCNIDPASGISMVTKFAVACSGFKDKNLP
LTYKVIVSELDSIGDISSVDENTLGTIMYLGTQPTTPAFFLPVGMATNHYNLRLYAQVYD
SLGTFSQVTLQATVKAPTVRDSSKNVVQQLLNVTQLNSSLSTLLQKQDWLPAGYLVYVVT
SVFNNIKWELELQGDRTRVLEYLVNQSFMLAMRTMDEICQSVMVITKLTQKALDLSQPTS
EATTLLLRQANQALQAYQQENKHLHSQQIEILCTGILTSLSNLLKLAKTYHTSETLLFIM
QSLSDMILANMVPGSKTVLRTSNFNMYVEKVENWNVHQAFRNESRCSNCLRATLNTSTVP
GLPAKAPVSVMFCKFVDDPFPWLTYPENISTDVVGFRMTGAADNGNAIEIAPDTAEVYLV
RKDLTSSSFNLTVGPGIKSAGFSKMTTGGISFEVDGRGFGEVLIHIVTNVTVLFEALVYE
GIQLIPTNLMAIFLVPHDIPPIAKWSGLFDPNCSVKEARVVCLSSTLLRTIAQRRHSFKY
NISVVLQASRFVFKPTNKLVRIALFMVHCLDMYGIQSDWGQSTCVLGERTTWKTIHCICR
KARRSRRQLTYSYMHIHFVTAKVIVVPNPVDLRLQVISNVTQNPVTLLAVLCIMIVYVIL
ASWALHRDVIDQYLHDNVVILTDNDPFDTICYLVTIFTGSRWGSGTKANVFIQLMGTEGT
SDAHCLTHPYFQTLYRGSRNTFLLTTKNDLGDIHSIHVWHDNSGKAPSWYLSRVKVENLF
SKRIWLFVCRRWLSVDTTLEETFPVTHPDESLKKTDFFMIDLNDKLGKNHMWFSIFTDIV
PKPFNRLQRLSCCLAMLLSSLVCNIMFFNLNITKQPESRQGHIIRSMVIGVESALITFPV
QLLITFFFTYSQKKPKVDTDKVAPQKHPLMSEEGLSWKDRLKKWHEYEMKTLTSKAANPA
SAPEEKDANKASKTSQAPDTQTSNKNFSNNNLEDSKDVPPKASSTQLHATRSVKKTQIIL
PRRCVYIAWFLVFATSGVSSFFIVFYGLTYGYDKSVEWLFASFCSFCQSVFLVQPCHILL
RSGTRMHRPKYCKNLSWSSKYHYTEIRLQELKMTPEETEQLHEDMAYIRSLSIYQPITED
KIQIFRRKNRIRKRSFLFLSYLVTHFIFLTLLLLLIFPLRHNDSFYYNQFVRHRFSMDLA
TVVKLGDIYAWLNGVFLPLLHNDKSPTFLPDSSSKILGLPLMRQVRAKPSNKTCLLAKKF
AQSRIAGELHCHPQYGIDPEDTRHYPGVWNKAGKRSIDKTSNGFTYKPPGRKWVYYSYGV
LNTYGSGGYEFYFFPEQQMFNSTLRLKELEGKNWLDELTWAVIVELTTLNPDTSLMCSIS
VVFEVSPLGVVNSSLSVYSFPLADFNSRSSAEIYLYVAILIFFCAYVVDEGYIIMQERAS
YIRSMYNLLNFSLKCMFALLIVLFFQKHLLATKLVRLYNTDPEAFIPFHAVSRVDHFMRI
ILAFLLFLTILKTLRYSRFFYNVRLAQKTIQAAFPGICHTALVVSIYSFMYVAFGYLVFG
QHEWNYSNMIHATQTIFSYCVSAFQNTEFSGNKILGVLFLSSFMLVMICIFINLFQVVIL
SAYDEMKQPVYEEPSDEAEAVTYLCDSLKSGFDFLTSGPQDKDQSDFFEDMLYGQPEKNT
RRFLGLKARNINGKKMIYLVV

>Canis familiaris_PKDREJ(ENSCAFP_43086)
RAAPEPATDGPRPYPSLVAKTRCPTDGPTTPVALEAVNLAGPAAGESSVPCKLLAQEPCI
VPEVKITRNQEGVPMLVKRNKEGILNVTFKYYCPATSYILPQWQVFSVSSASEVPDWSNP
LDVPELQSGINPVYLYIPPKSLAWGMYVFNFSLIFYVERNRTIAAVGSDIIYVNITKSDL
QAVIAENPNITINFTDTLLLNGSGSSDPDSDNPLEGLIFSWYCTTEPKQYRGDKITVMSN
KVCFPHYTNLRWPRASGPVLTIPPGTLKGGGVYFFRLVIRKGGRKGFVDRTVHVLKGPAP
VASISCIENCDAVLVISDRFSLFLNCTNCSSSLDLYEWSLLSSNGSQVPFDWVRHTTTGK
TSAYLTLKAFVFRNFSEAQFWISGHIASWSGHDLHFRHSFIINRVPQIGHCTIDPPKGVS
FITKFVIQCQNFKDNNIPLTYKIIVSDLHGFGQISSVKENSLGAILYLGNQSTAPPSFLP
VGMLANHYAMKIHVQVYDSLGAFSQVTLYSTVHSPTDEFSAKDVLDQLFNFTMGTNSSLS
ALLRNREFLPAGYLIFIAASVLNSLKPELTLQADKARLQEYLVNQTFVLPNSTLVEISQV
VMSIAKLTQTTSGCTLMTQKLATVRIWQANQALQQSRQRDAHRHSEQIEIMSTGILTTLS
NIIKMIVNYEVVDEPFYEMELLADTILDSKVPGNETTALTASSLNMYLRKTEKWDVTNAF
GNKLTSRNYFNPTLNVSSVPSLPANAPISIMFCEFVDDPFPWLKYQENYSVEVVGFRMTG
TTPSGSVTEIVPDIAEVYITRKNLSFAAFNLTMGPSNEPGKVEESLKRTTGEFSFEVDSS
VVKEVLVHIVTEVTVIFTVLVYAGSQITPSALVATFFVPYDIPPVANQSDLFDSACTVKE
ARVVCIPPSLLQVIAQRSGSTECAMIIVLQAPRFVMVPSVKLVRIALFGAYCLDMYGIQS
DWREDTCVLGEKTTWRRVHCICKHSGRARRQLDAIRKAGKHLQTHFLTAKVIVIPNAVDL
RLEVIKNVTQNPVTLFTVLFIMLMYLILAFWALHRDGMDRFLRHQVIIILDNDPYDKVCY
LITIFTGSRCRSGTRANVFIQLKGTEGDSDVHCLSHPYFTTLRRGNINSFLLTTKSDLGD
IHSIRVWHNNEGRAPSWYLSRIKVENVFSRQIWLFMCRRWFSIDTSLDRTFPVTHPDQPL
NKMDFFLIDSIYKLGRNHTWFSIFSSVVARPFNRLQRLSCCLAMLMASLLCNIMFFNLNP
EDETEPEERRYIRSMMIGLESVLITIPVQLLVDFLFTYSQREPRVALEESAPRKNSLVPT
SEHWEEYLEKWHALEMVDAQTKVALKLPPGKSARPQEASAKDPPVALHPHKKGQSKVSGP
QKKKTKASNQNAKDNKNQNAQPVTMTEPSLIVSHHLEIDKKCRVNLPWYCVYLAWVLIFI
TSSIASFFIVFYGLTYGYDKSIEWLFASFCSFCLSVFLVQPSKIVFLSALRGNWRKYCKN
LSWTSGYCYTEIKLHSRSFSPEELEKRHEQILQLRNSRMYQPLTEDEIRIFQRKKRIKRR
AFLFLSYILTHFIFLALLLSLLALLRHTDSFYYNQFIRDQFSVDLSSVTKLADIYRWLNS
VLVPLFHNEQDPTYLPDSSSKILGLPLLRQVRAKPGDKLCPPAKSFAHTGMEQEIRCHPS
YGTDLEDTRNYTDLWNTVTKRAVDKNTNGFTYKPPEKVWAYFSHGLLHTYGSGGYAFYFF
PKQQQFNSTVRLRNLQSSNWLDEKTWAVLLELTTFNPDISLFCSISVIFEVSQLGVVNTS
ISVHSFSLADFNRETSAEIYLYVAILIFFLAYVFDEVYVILQERASYVRSVYNLLNFALK
CIFTVLIVLFFQKNFLATGIIRSYLSNPDDFIPFHSVSQVDHVMRIILGFLLFLTILKTL
RYSRFFYDVRLAQRAIQTALPGICHMALVVSVYCFVYMAFGYLVFGQHEWNYSNLVHATQ
TIFSYCVSAFQNTEFSNNRVLGVLFLSSFMLVMICILINLFQAVILSAYEEMKQPVYEEP
SDEAEAMTYLCRKLRAIFRFLTFQPKDEDEPEFFVDMLYGQPEKNSRRYLGLKTRNINGK
KMVYLVV

>Felis catus_PKDREJ(ENSFCAP_6068)
CLEATLFNPSWQVFSVPSVSDVPDWNQPLDVPQLSLGRTPAYMEIPPNSLSWGVYVFNFT
LTIYTRKSNTPRATGSDIVYVTVLRSPLQAVVIPARPNITMNFTDSLVLDGSRSSDPDSG
NSSEGLLFSWYCTKDKNNYQGETIIVVSRKVCLTAKQTDLRWKEASGPILSFLPRTLRGK
DAYYFRMVIRKGSRTAYADRRVHVLPGPRPAAHISCIENCNRNLIISDRFSLFLNCTGCA
GDRDYYKWSILSSSGKEIIFDWARQTTTGRARAYLTIKAFAFRDFSEAEFLVSVYSITWS
GAGLTLRYSFAINYAPQPGQCNINPAKGLSLLTKFVIRCTNFTDKNIPLAYKIVVSDLYG
FGQISSVKENTLGAILYWGHESTSPPSFLPVGGLANHYVMKIIVQVYDSLGAFTPVTLHA
TVRAPTDKISSKNVLDRLFNFTMGPTSSLSTLLDQREFLPAGYLIYIAASVVNSMKADLT
LQADKTRLREHLVNQTFVLPNSTLEEISQVVVCMAKVTQTTSGFTRMAQKLATARVWQAN
HALRQSHQKHKSFSSERIEIVSTGILTSLSNILKLSVPYEVVDEPFYGLEFLADTILAGM
VPGNETTAMTASSFNMYLKKTEKRDINEAFTNKKLGRNYFRPVLNASSVPLLPENAPIST
MFCEFADDPFPWLSQQESYPAEVVGFKMTGIPAKGNVLEITPDVVEVHIVRRNLSFAAFN
LTVGPDNAPHKVNEPFKRTTGEFSFEVDSSAVNEVLVHIMTEVTLVFTVLVYAGSEITPA
ALVATFFVPYDIPPIANQSDLFDQACVVKKARVVCLPPSLLQVIAQRGSSSECTVTMALQ
APRFVMAPSNKLVRIALFSVQCLDMYGIQSDWREDNCVLGEETTWDRMHCICKNPRRARR
QLATIKKASLHLQTHFLTANVIVVPNPVDLRLEVIRNVTQNPVTLFAVLFIVLVYVFLAF
WVLHKDAMDQLLRQYVIILPDNDPYDKVCYLLTIFTGMRCGAGTRANVFIQLKGTEGDGN
VHCLSHPYFTTLSRGSINTFLLTTERDLGDIHSIRVWHNNEGRAPSWYLSRIKVENLLSR
HIWLFLCRKWLSVDTSLDRTFHVTPPDQPLEKKDYFLIDSIYKLEKNHMWFSVFSGVSAR
PFNRLQRLSCCLAMLLSSLLCNIMFFNLNRKEDTDPKETKYIRSMMIGLESVLITIPVQL
LIAFLFTYSQEEPRVTVEEVSPQKTPLMRVPSEYWEEHLKKWHAQETDGAPARAASKLPP
RKSPKAPKAPEQHRGKKAEGKVSRPRDVNMNASNRNAEDDQEAAPAQPPSQANPPELQEK
HRIVLPGCCVYVAWFLVFATCSISAFFIVFYGLTYGYEKSIEWLFASFCAFCLSIFLVQP
SKIILLSGVRTSRPKYCKNLSWASKYHYTEIKLFHAKMGPEEMKRRHEQITQLRSSRMYQ
PLTEDEIRIFQRKKRTKRRALLFLSYILTHFLFLALLLRLVALLRHTDSFYYNQFIRDQF
SVDLGTVTKLEDIYRWLDHVLLPLLHNDPNPTFLPDSSSKILGLPLLRQVRAKPGEKLCP
PAQDFVQNSTDRDIHCHPEYGTDPEDTRSYSNVWDKVGKRAVDKNTDGFTYKPQEKTWAY
FSYGLLHTYRSGGYVFYFFPEQQQFNSSMRLGELQSNNWLDEKTWAVILELTTFNPDVSL
FCSISVIFEVSQPGVVNTSMSVHSFSLADFDRRTSAEIYLYAAVLIFFVAYVVDEGYIIL
QERASYVTSVYNLLNFALKCIFTVLIVLFLRKHFLAAGIIQFYLSNPVEFVPFHAVSQVD
HIMRIILGFLLFLTILKTLRYSRFFYDVRLAQRAIQTALPGICHMALVVSVYFFVYMAFG
YLVFGQHEWNYNNLIHATQTIFSYCVSAFQNTEFSSNRVLGVLFLSSFMLVMICILINLF
QAVILSAYEEMKQPVYEEPSDEAEAMTYLCCKLRTVCRCVFFQPKARDKPEFFEDMLYGQ
PEKKSRRYLGLKTRNINGKKMVYLVV

>Bos taurus_PKDREJ(ENSBTAP_54940)
MGPGPALLLLGLGLGLGCGPGRPPPPPAPAQAPASRDPGERGAGFGGLGAGRARVSLRAR
AAPGGGIFLSGRRGLCLPAGRPPSLVPRCVRAHVQLRARRAPAAAAPAPVDLQLSAPGGR
LSLRWLSRLPRSLGPLEWTFRLGLLGPAAAESRALPRRALQRGRRSYPGFVARTECPTDR
PTPVVLEAVSPNSSEPTESSVSYQVFRPWPCKLDPVRINRNDDRPVRLTRDMEDTFNATV
ILFCPIQEYYYRGWYIYSVPYVGAVPDWTKPLEKPPVKFSRGFFEVTIPPYSLPWGVYLF
NFSVVVRTRDPQVPGKNDSDRIYVVIFRRPLNAVISGPSNITINFTDGVTLNGNMSSDPE
ETDPLEKERLKFLWYCTTNSRNYDGENITVISKEVCLPEQVDLKWTWASGPILTLSPETL
QGGRVYFFRLVIQKTSRSAFADATVHVLQGEPVASTSCIENCDQVLVLSERFSLSLDCTG
CTAGRDVYRWSILTSSGQEVPLDWTGQTSTGRNGAYVSIKAFAFWNFREDKFWISLNAAT
WSGVTLVLRYPFVIHHVRITTDCKIVPEKGISFITQFVVICTHFKHKNIVLTYKIIVPDV
HGFGEISSLKENNFGSILYLGKNSTSPPSFLPVGVLDSHYALKIIAQAYNTSLGAFSQVN
LYATVRPPTDVKSSPTVLEELSNFTMGPNSSLSTLLQQQDFLNASYLIYVVASVLNSMKS
DLSLQADKIKIREHLFNQTLILPINTLVNISQVVMAVTKLTEKTSEISAFSQKLATVRSW
QASQALQDSHQRDKSISSEQIESVCIGILITLSNILKLLVHYEVFEEPFHVLESLADTVL
AVKVPENETTALRTSNFKMYVKKTEKWNVTKFFSTQKHCQNCFYPSLNVNSVPSLPASAP
ISTMFCEFADDPFPWLNYGENILTQVVGFRMTGVEATGDVIEIPPDAVEVHLIRKNLSFG
SFNLTVGPSSEPYAVDESATKTTGAFSFVVDGTAGRDVLIHIMTDVSVLFTVSVYAGREI
TPNSFMTSYLVPHKIPPIANESDLFDPECAVKEARVVCLPAALVQVIAQRTDSSECTIAV
VLQAPRFVLKPNNKLVRISVFSSECLDMFGIQSDWREDTCAVGEKTTWQRVHCICKNPRR
AKRQLDIIKQANLRLRTHYLTAKVIVVPNPVDLRVETVKNVTQNPVTLFTVLLIMLLYLI
LAFWALHRDETDQYLREHVIVLLDNDPYDNVCYLVTVFTGSRCGSGTRANVFIQLHGTKG
SSDVHCLSHPQFTTLYRGSICTFLLATKKDLGDIHSLRVWHNNEGRSPEWYLSRIKVENL
FSRHIWLFMCRKWLSIGSSLDRTFQVMPPDKPLKKMDFFLIDLSYKLGRSHLWFSVFSGV
ISTPFNRLQRLSCCLAMLLSTLLCNIMFFSLEKEIEAEPQEQRYIRSMVIGLESAFITLP
VQLVIKSLFMYSQRRPQVTLHEVTPRKHPLKAPARQHWEERLGNWHAYEIDKASSQEPVS
NRHHAKPKGSVNVTSKRQPPAKNQSNVTQAQSKFSNIQGRNINTNNPNIEDNTNVSDEQP
PQPGSTALKEKTRMVLPQWCVCVAWLLVFLTCAVSSFFIIFYGLTYGLEKSTAWLFASFC
AFTQSVFLVQPSKIMLVSGYRTRKAKYCKNVSWIGNSRFSEIKLHNIRKDPEEMDRRHRY
VMELRNSRMYQPLTQDEITIFQRKKRIKRRAFLFLSYILTHFIFLALLLSLVTILHPTDS
FYYNQFTRDQFSVDLAGVTRLEDIYQWLNRVLLPLFHNDPNPTFFPDSSSKILGLPLMRQ
VRAQPGDIMCLPAKKFVEGSLKGEIRCHPEYGIDPEDTKNYSGSWNRVSKRDTDKTTRGF
TYRPPEKRWAYSSYGLLHTYGSGGYAFYFFPAEQQFNSTLRLSELQKSHWLDEKTWSVIV
ELTTFNPDISLLCSISVIFEVSQLGVVNTSLNAHSFLLADFNRKNSADSAENYLYLAIFI
FFLAYTVDEVYVITQERTAYVQSVYNLLNFALKCIFTLWIVLFFRKHFLAISIVQAYRSN
PEDFIPFHAVAQVDHTMRVILGFLVFLTILKTLRYSRVFYDVRLAQRAIQIALPGICHMA
LVVSVYFFVFMAFGYLVFGQHEWNYSDMIHATQTIFSYCVSAFENTEFFNNRVLGVLFLS
SFMLVMICILINLFQAVILSAYEEMKQPVYEEPSEEAEAMTYLCRRLRSAFCCLCFKPRA
EDEPKFFINMVYGQPEKNSRHYLGLKTRNINGKKMVYLVV

>Gallus gallus_PKDREJ(ENSGALP_22989)
PASAAAAPPPRARSPAPRPGKHRGFVAKVNSAQSGLTPALPRVSASTEPALLHQEAACKL
NSVTIQKPPLHTSVIHQKKGTTFYLRARVLVDCSLRVSIKPKWIFYAVKDMKTNPDWDRP
LDISSLHGVHTVQLMVPSWTLDYGMYQVYFTASVYVLGTKRSFSKTDRIFLEIERTNLVA
SIAGGVFRTVSFFDNWTLDGSVSYDPDSAERLKGITFTWYCTKKLSDYESMRIGAGNKCH
PAQRDLRWLTPSGAVQVVAPESLPGNAVYHFRLVIQKDRRKSYADQSVSVQSGFSPLLDV
ACLENCGSTVIPTERFTLSGKCLNCRTSSQPVYHWSLWLENSTEISFDWSSRTSTGRSGA
YLSIHALTFTSTADQSYILLLKVTTWGGRSSLYRYAFKVNSPPRAGKCSISPHRGTAFLT
KFVVQCSGFSDSNLPLTYKVIVASDVSKTAKINSVEDNTFGTILYFGYQPRMPPSLLPVG
VPSRRYTLTLYVQVCDSLGAFTQLSLHVRAQNPVKSRPLAVVFHDLLASVSGSSAPMTAY
LQTGDYFNAGYLAYLAASVLNYIEAAPTLQISKAQLRESLAKTALNISVESTMEINQVVA
SLFQVTEQPEEVNVRSQEIAITKLTEVTGVLKTQRNESHWSEQTEIQTSGILRCLSNILR
AALLRRSNKGPMYSMENLTEIVFQGKVPGEEDTVMETKNWRITLMKDENWDVENAFSPTK
ACKNCFYPTLKNGNYSRLSYDAVISTALFEFDENPFPWLAYTSEIATAILGFKMAETKAN
GDLLGILPDEANILIARKDTESSTFQLAMGPDKTQTYTTGGFSLEVNRDTKIIYIQILTK
LEVAFQVLVFSGTNVTQNFPIASFDAFHNTTTVASKTKTVDEECNIKTPYIICLPESVLK
GAAQGSGAQSRNISIVLLTPYITRYPNMRLVSIHTFSDHCLFLGGVQNQWREDMCRLGSL
TNWQRVHCVCNMKRSHRSRSVLTATNTSTFDIKFLAAKVIVSPNTVDLKRNLIADIPKNP
VTLLTVLFIFSAYFLLSLWAMRKDRAEMVSKDKIIVLPDNDPFDKVSFLVTLYTGSRWGA
GTSADVFLQLIGQNGTSDIHCLRHPELPAFRQGSTDCFLLTAKEDLGDIRAFRVWHNNRG
PSPSWFLSRAKVEHVSTQKTWFFMCRKWLALDKGDRLLERTFCVTNPKAPLSRKDYFFID
LANGLKEGHLWLSVFAQVLTGTYSRLQRLSSCLTILLLNLFVNIMFFNADKNEESPMHLR
YLRSIAIGIECALITIPVEMIIMALFKYSQKNPKRSLPLLSGNLKNWRGRLQKWKPSETS
AQSGSISSPQNVPGDSNSQGLTHYRKMRSQVKAWQRGLPSNSNFSNNYAKEAGRKQATQR
YLCAFSQETTHSFCWWCIYLSWVLVIVVSGVSSFFIVLYGLSYGYQTSLEWLLASATSFI
QNVFFVSIIKIICYSALNSVRPKYCEHITWFTQDLSSEIKLDKEAMNEEEMQEKHFRLAQ
VRDTKLYKPLEDGEIAKMETAKIKVKAFIFIKDVIGHLVVLVLVLYFAYSTENTNSFHYN
QFIRNQFSPRLSAVVKLEDIYMWVNDTFLPLIHNDVQRTFLTDSSSKIIGLPRMRQVRAK
DTEKKCFHPHSFVNKFVISKSHCLHKYGRDIEESGDYAGTWTKVANCSLSKDTSSCHGFT
YEPNRTPWTYFSYGDLHTYGPGGYTFYFFPEEGRHNSTTRLNLLQERGWLDEKTWAVIME
LTTFNSDGHLFCSISVIFELSYFGIIKPTLSVHSYALPIFYQQTKGQQLFFLSAVAFLLM
YTADGLYSLVQGKKCTNKVSRTISFILKSAFFLFVPLQIIKFKMGADIVHFFLLYPNDFI
PFHAVSHLDQNLRNTLGFLAFLAVLKTLKYSQLFYEVRLAQRSILAALPGISSMAFVVVV
YFFIFMAFGYLMFGQHEWNYNTMIRSAQTIFSYCVSAFRDTEFSSSRLLGGFFLASFLLV
MTCVLINLFQAVIMSAYGDRKQLVCEEPSDEARVAAFVLQRMKKMLCFLICRTAKRGDPN
LCHIVHNGQAERRLQRRTVNGEKMVYLVT

>Anolis carolinensis_PKDREJ(ENSACAP_15021)
ATQFIPDSVLPFNPALYTGFVAKMKCISSKFVLMVLKATFNLYGSKVIESRLACHQNACS
IAKINIQRSETSKFILHYAPGTEFTLATDTQINCPGPKQTDVIWNIYKVENRASTPDWSK
PFNPPGIRKRNDMTLNIPSSSLDDGLYVFNFSMKLKSLDTWDITKSSDSVLVEIGPDNLM
AAIVGGNFRTVSFSDQWILNGSIFSNGEMIQSFQKGLSFIWYCTKHKSDYASMTLSRNGK
CHPDQADLKWITSSGPVQTVRPKTLQGNNTYYFLLMVQYGSRTARAKQAVYVRIHSPLIL
NVACIENCDKALVPTERFCLSGKCLNCRPNQPSYYWSLYSIQYNEIDFDWFSKTTTGRSS
PYLRINAFAFETMTEHSYILTLKVSTTEGQTAIYKYSFYVNGPPRLGKCVLNPNIGIAFL
TKFIIQCSGFEDKNEPLTYKVIAAYNQIETSTISSIENNTLGIIIYSGHDYKTPRSFLPN
GVPSQNSALVIYIQVYDALGASSQVTLQATVHDEKKSKSLDIIHHKLHSLINGQSAPMTT
FRITKDYFDIGYFVYMVASVLNNVETSFARQDSTSDLRQILLNMSAEIPANTAEEINQVI
LSICQVTHKTMEINEESQLIAIKKLKEASKALIRLRDKDFSSKETDILSSGILIGLSNVL
KASLSDYKKVNINVIKETISVMEILADLVLQDKVPGENETIMKTENWRIHLQKYMKGDLS
GNVSNRKYCRNCFYPKLKEGRHAELNVDAVVTTVFYVFEINPFPWLLFTEDIGTIVTGFK
MTGTQTNGDVISITPDLVEIIMARKDEVIFDLTIGPDKMLSKTTGGFSFETKRSTKDIFI
QIVSKRNITFQVFIYPGHNISRPPLATFTVSHHSPPTPIENDTTIPECAVVAPYILCLPQ
SLLWSPVYSNRGDKVSISIVLQSHPFVREQTTKIVRIAVFAAECLDLDGIEKQWKEGTCS
LGPETSWSKIHCICKAKELSTITGSPSHSPTFLAGKIKYSNPVNVGKSQSTQIHQNLVIL
LTLLFIFLLFIVLAIWAMRKDRADINSVEHVIVLPDNDPFDKVCYLVTVYTGSRLGAGTT
ADVFIQLTGERAVSDVHCLRHPEHFTFFRGAVNTFLVTSKIDLGEIYCFRVWHNNEGSSP
NWFLSRIKVENIYTKKSWMFICRKWFALDKDDGLIDRSFIVAHPKAPLHKLDFFMIDFAN
TVADNHLWLSIFAHVCTGSLNRLHRLFACLTILLCILFVNIMFFSADEERQMFSEHIQYL
RPILIGVQGAFISIPLQMIVTAFFKYSQEEPSVQSTTHALPAQYSTFMFGNLSNWKECLQ
KWYLIETASKDLGDHLQEFPPKALDSPKQEQSKTITWRHTSKNWTNCTIPEGAKTNNNVN
NNYLEKHKSYLQTRSPNIANMVFCLRPQIKVSWWNRYVLWIFVLVTSTLSSFFILLHGLT
FDYEASVEWLVASVISLWVNVFLLQIMNIAIFSSLKTLYPKNCKSLQWSSKAAYLEIKLS
DINMDADDMRELHYDLVRMRGTKQYHSLEEDEITIFKKRQKIQRQAFVFIKDVVCHFVFL
ILILNIAYSMENTTSFYYNQDIHNKFSNGLSRVNKVEDIYTWLRKVFLPLIHNDDKPTYL
SETRTKILGVPRMRQVRANITKKACFYQQSFVHKFVISKSHCLHKYGIDEENQRDHLGSW
TLPADKPVFELHVSIGTGRWKYSSYGELNTYGAGGYTFNFYSEENLRNSTKRIDFLEESS
WLDENTWALIVEMTTFNSDVDLFCSISVIFELSYLGPINTTLWIHSYKLPVFKELSKTEK
FVYVAVGYMLVFYIIDECYVVERQRLKYIKTVSNLINLGIKGVCLFFLLQLGFKFELASD
LSELHLLQPDEFIPFHRVSHVDRTLRITLGFLAFLIVLKTLRYSRFFYDVRLAQRSILAA
LPGICSMALVVAVYFFVYMTFGYLVFGQYEWNYNTMTHSAQTVFSYCVSAFKDTAFESNR
VLGGLFLATFMMVMICVLINLFQAVIMSAYEDMKQPVYEEPSDEAEVVNYLFNKVRRICF
FITCKKASTADTELFNRVLFGHPERRNKHHLGLKARKVNGRKIVYLVI

>Pelodiscus sinensis_PKDREJ(ENSPSIP_20635)
AAHFVRRSVLPFNPDLYTGFVAKVNCTRSGLTPAVLKVTVNTYASKVMESLVSCQKKPCF
IERLRIQKPDLVYPIIHTKKGTQLYLYAKMQVNCTDLVRTEQIWKIYSVQNFTTIPDWTK
PLNPPLIWRRHMLILQIPSFSLDYGLYLFQFSVKITTTEDVVEGSDTVFVRVEKSDLVAV
FAGGTFRTVGFSDKWTLDGSMSSDPDSADRLEGLTFTWYCTKHVSDYTNMIVSTNGTCHP
NQVDLKWIHFSGPTQTVVPETLRGNAIYHFRLVIQKDNRKSYADQTVSVRPGSPPLLNVI
CIENCGKIVIPTDRFTLSGKCLNCRMTSRPVYHWSLFSGSFTEIQFDWASKTSTGKSSAY
LSIHALTFIKIADRSYTLLLKISTWGGRSSTFRYSFYVNSPPKIGKCAINPSSGVAFQTK
FVVQCSGFSDNNLPLMYKVIAASDLSKRSRITSLEENTSGTIVYFGYLPKSPPSFLPIGI
PSKKYTLIIYVQVYDSLGAFSQVALYPTVQDPVKSRPPSIMLNELLTLTTGSNAAMTSLL
QIGDYLNVGYLVYMVATILNDIKTVPSIQVSKTEFRESLLNQSLHIPTTNIMEVNQIVAC
VSELTQESTEVNRKSQELAIRKLKDVSEALKTFRNKSLGSEQTELLSTGILTGLSNVLKA
SLLDLRNVNVNAVKQSFAVMETLTETVLQGKVPGENETVMEAQTWNINLNKDEKWDVTNT
FSAKKDCKNCFYPTLNQGDHSELPVDAVIATVFYEFEENPFPWLAYRSDIVTTVTGFKMT
GTKVNGDVIGIMPAVAEVILARKDKESAAFKLTLGPDKTLPKTTGGFSFEVDRNSKDIFV
QILTKLKVSFHVFIYLGVNVTHTSPIASFFASHNEPAVSSGNKSNNTDCAIKAPYVICLP
QSLLRATAPGSGTDKWNISIILQSPPIVRSRNRRLVSISLFNAACLDLDGVQSQWKEGTC
ILGPHTSWQRIHCICKTKQQTKRTASRPGLGSSKFNIKFLASKVFVVPNPVDLEKSLLAK
IHKNTVTLLTVLFIFLVYFLLALWALRKDRIDKASRDKVIVLPDNDPFDKVCFLVTLYTG
SRLGAGTTADVFLQIIGQNGTSDVHCLRHPNYHSFFRGGTDTFLLTTKNDLGDIYSLRVW
HNNGGSSPSWFLSRVKVENMYTKEFWLFICRKWLALDKDDCLLERTFVVTHPTVPLAKMD
YFLINVANNLVDSHIWLSIFAQVVTGSFNRLQRLSCCLAVLLCTLLINIMFFNIDKNKDV
ISIHLRYFRSIIIGIESALVTIPVQMIITALFKYSQKEPFPHCAAQNHPKENSPFMSGNL
RNWKERLQKWYLAEAPTQSKMNQRTPKLWSNCTISEGAANTIAAEEENASGTSTAEAKAK
QTQSPNSNFSNNYAEEKNANIQEERKPLNIPFMLFRKRPQITFCWWCIYVSWILVIAVAG
VSSFFIVLYGLSYGYKTSIEWLLASITSFFESVLLLQTLKIIIFSALSSVYPKYCENIPW
STRDNYLEIGLDEVTMDADEMREMHYEIIRLRGSKQYQPLQEDEVTIMRKREKIKIKAFI
FLKDVVSHFVFLTLILNIAYSTESTNSFYYNQVIHKQFSLKLSSVDKIEHIYLWVNNVFL
PLIHNSQQPTFISDSWSKILGLPRMRQVRAKITEKKCFQPHSFVNKFVISKSHCLHKYGS
DPEERGDYIGSWTKGPNTSVPHDISSYAGFTYQSNRNHWVYYSYGELHTYGPGGYTFYFF
PAEQRPNSTKRLDVLQHSNWLDEETWAVIIELTTFNPDVHLFCSISVIFEISYFGLINTS
LSVHSFTLPIFQQQSRTQIFVFVTVLAFLLIYITDEIHIIRQEQTMYVKNISNLINFGLK
SVFFFFVFLQVIKFKMGADIVKFYLLNPDDFIPFHTVSHVDQTLRIIMGFLAFLIVLKTL
RYSRFFYDVRLAQRSILAALPGICSMALVVAVYFFVYMAFGYLVFGQHEWNYNNMIHSAQ
TVFSYCVSAFKDTAFTSNRLLGGLFLASFMLVMICVLINLFQAVIMSAYEDMKQPVYEEP
SDEAEVITFLVHKIRRLWYFITCRTPSASDPDLFNSVLYGQAERYSHQHLGLKTKKINGK
KMVYLVI

>Ciona intestinalis_(ENSCINP_8806)
MTSDVYVASGDNQGDSNLNIRTTTLEGSGIWFKVKKGLRGLWGTRQTEDTQTDRELYIRT
TIRELVIYVFFIATLCILTFGMTSSTHYYYTKVMQELFVDAQFPDTKNTFKGMTTMQDFW
RFSEGPLMDGLYWETWYNQKNVSEEDLGYIYYENKLLGVPRIRQLKVRNGSCEVHPDFQE
EITACYDSYAKAKEDTSPFGSENGTAWVYHTEDELDGSSHWGLLDYTYSGGGYYQDLLDT
KTKSLAIIKNLKENLWLDRGTRVVLVDFTVYNANINLFCVVRLVVEFPATGGAVPSYQFR
TVKLLRYVTTYDYFLMGCEVLYMLFILYYIVEEVLEIRKNKCSYFKSVWNCLDVLVILLS
IVAFSFNIYRTITVDSLLGKLLDQPLTYPDFEFLGFWQMQYNNMVAIVVFFAWIKIFKYI
SFNRTMTQLQSTLSRCSKDIAGFAVMFFIIFLAYAQLGYLVFGTQVKDFSTFQESIFTQF
RIILGDFDFHALEAANRVLGPIFFLTYVFFVFFVLLNMFLAIINDTYSEVKAEISMQKSE
FEISDYIKRGYNKVLEKLSLKKDRIRDIQDAIQTADLNQDRHLDWEEWRLDLKMRGIPDA
EIEAVFAKYDQDGDMILNENEQKKLKADLERQKVIFNYLFIQHCSKPRSKGAVSHVSCND
SANESDDDDEDRPISSKNFVSRDDFQILARRVDRMEHSIGSIVSKIDAVIVKLEAMERAK
LKRRETMGKLLDNITEDERNGRSDDELRREQMERLVREELERWDSDASIASTGRRGNRPQ
SGRSTASSSASSNRVRVPGSHGNTSSA

>Ciona savignyi_(ENSCSAVP_1730)
GLWGTRQTEDTQTDRELYIRTTIRELVIYVFFIATLCILTFGMTSSTHYYYTKVMQELFV
DAQFPDTKNTFKGMTTMQDYWRFSEGPLMDGLYWETWYNQQNVSEDDLGYIYYENKLLGV
PRIRQLKVRNGSCEVHPDFQEEITACYDSYSQAKDVSPFGPENGTAWVYHTEEELAGSSH
WGLLDYTYSGGGYYEDLSDTKAKSLAQIKHLKENLWLDRGTRVVLVDFTVYNANINLFCV
IRLVVEFPATGGAVPSYQFRTVKLLRYVTTYDYFLMACEVLYMLFILYYIVEEVLEIRKN
KCSYFKSVWNCLDVLVILLSIVAFSFNIYRTITVDNLLTSLLDQPLTYPDFEFLGFWQMQ
YNNMVAIVVFFAWIKIFKYIRLGRFNRTMTQLQSTLSRCSKDIAGFAVMFFIIFLAYAQL
GYLVFGTQVKDFSTFQESIFTQFRIILGDFDFHALEAANRVLGPIFFLTYVFFVFFVLLN
MFLAIINDTYSEVKAEISMQKSEFEISDYIKRGYNKVLEKLSLKKDRIRDIQDAIHSADL
NHDRHLDWEEWRLDLKMRGIPDAEIEAVFAKYDQDGDMILNENEQKKLQADLERQRMERD
KSGAATPGGRPASARSKGAVSHVSYNDSANESDDDDDDRPISSKNFVSRDDFQLLSRRVD
RMEHSIGAIVSKIDAVIVKLEAMERAKLKRRETMGKLLDNITEDERNGRSDDELRREQME
RLVREELERWDSDASIASTARR

>Branchiostoma floridae_(XP_002595676)
MQPDVLVTGKHGVLRPRLYWIYLLCGLLACVGPWPALGHTTEAPTTEGPTKTNCETPCPDKCLCSAVPKA
CTVDCTGQGLRQVPSPTGLPIPTKKLILSENNVSTIAEDAFKSLQNLEELIMDRNNISSLPNRVFNNLSS
LKILDLSSNELDNLTYGVFDDLVASNSSLTSLSLGSNPYQCTCDLFWLPLWLTVATGANITLPDQPNITC
VDPQTNTVKHVDQVDFSPLNCKPCKLSAGLLAILRKHRHSKVHWHEKHSLSRHRSSRGRRNAQSYGACYT
DTDTGEESLVFFQYEQSGSHDTASCNAICYAQGYSYGGLPDAQDTCYCGELAESFPFYTGCKLLWCEWDH
TISISIQQSVCQGHLGIPSSFKTFPTFHISNTRTYYSINEDIDFTLAGILTDSTKSYVWDLGDGSPQVNK
TGLSINHKYSVDGTYTLLVEGLYNGTVVTTWMSVVIVTPITGVTLTCPPSHYTGSDAFSVTLEAQTGYNI
SVQWLVSDYHVEGFITDEPDADYRQYYMVGSVVFDSMDIPAVNMTAQAGVASANTKRLLLFPGMWFQHTG
CQSLPSPYATCVSGQLCNATDSCPAGQQYCYLSSSCQAITEPCSEYAMMNQALPPRYINAQPNYTLAGET
NLHISVTERTLVRVDISQQPITVYQDDIIGVQFDSKDALQYYNSSTSEWVQSALYMEQDDWVQMWTQPEE
YSDTWFDDALFEIRAMYTVSETFSYSPSNADIIKARPVGTVTFAAIVENPVTQRTARNCTITFEDAIEGA
ELIYPIPGDDGIIRLETGKEYNFVVMITKGTDVSATFIFWSEVHAGIPVQDTCPDDMEDVPQECTPTSNT
TSYAFYSKQYDSSTNQFHLSVQLTNLVTQVTATSTVQVDEVISGVTISSSSPRTAEGIEQTFTVSYATGT
SVNSYEWYIDDSVVLNADSSSFFHTFSEASTHTIYVVIENPHGAANATLDITIDQMEAMQDLTFVNAPAL
EAAGDAVTFTATAAVDSYYDYTWQWDYGDGHSDTISSSAPYTGDTPIANTYLVQHGESINHTFANPGIYT
VNVLVFNNYGNISAQHTVEIRPKLTGVSVTAEPVAVERGEPVTLTATPHGATEDVTYKWNYDDSSTDEGS
SNVSIHTYTVAATYNVSVTADNGVSKAASFVLVKAQVKVTGLELSTDPEVTEMNEVTTLTATVQTGTDLL
YNSDMGDGFVLYNLTSPFVHTYTYPGNYTANVTAFNDISSEWETITVMVISSFTIDNVTSGSCTELGKMT
TFEASITTDNIDILQFTWYFGDGNATTVLGSPIITHRYGTTGNFTVRLKVENTQKVLWETIYGCVQEPIS
GVYVTASGPTALGHETTVNVVLGTGSHYVYRVDFGDGVLETYDGGSDVKHVYGSAGSYNVTVTVENEVTT
TTVTTTARVVEEISGISITHNGTNQDFVRSQSLYTYQANVARGTEVDYTWNFGYDQEIVSGEIQTYQYDA
SGIYIVTVNASNDVSSSSNSEIITVQDTVHGLHLSSNATEILVGSSIFFDADITAGTDPKYTWKLCSTCS
SFVGSDSITRDFDAVGTFEVSVNVANEVSSEEVSTSVTVIYPVKGAQINGDLTAGSLHAAGQAYTFSASV
SEGSADHYQWEVSKYGSHIGTFTGYEVHITFPDYGQYDVSVVVSNSVSDSEASMTVDVIELVTDVDLTAS
KTMASNEDEVTFTAASTGTNLTFVWSLGDGSPNIETTEPQVQHQYNLAGTFLVTVNVSNDLSSLKSTSLP
VEILEKISGLDLETTTTDTNYYAGQNEFTNFVATLTSGSNVTYSWRFTDGGRETSFNGLDLDEAKMVYNM
LGNQTASLSADNDVSHQNITRTIVVQKRPTVVTLWPNASYVETLDVISITQQVEGTDLEYELDFGDGQQM
IGDSLPSTILHSYSKTGTYALSLTVRNFVGQEEYVVSITVLQRIEGLAINTNCIMPYCTNGFLSLGEELE
YAAKWVQGNNITFTWVVTQADGSAIGSTGETMTFAPTQLGSQSVTLRAENWLNSVSVAETFTVQEEIVSA
TLTTSNIINLYENATVSFHMGISSGSDVYYEWDFNDGFSIFETSVSDQNRTFPTAGDYLVRVKAFNNISL
VVKEIAITIRELMCQEPTVDRVGLFSKEVLRSSEAFLEVDVNTFDCTKYRVIHQWTVYQGSQCGVNNITL
PSSVNRASTRLILPKQTLGYDLYCIEYQIVYQDTPVLSVVRFSLRVKASPLTPLIKGGTERTQSSTQELL
LDGTSSFDPDTPDKTGLTFQWNCQAYTTQNGPNDPTAACNVIDWATLQHKSLVSIPANTLPEGTTFLLNL
TVGKQDRVPQSAQQTIVVNVQNVPSVFITCVSCISLNTMTISWNQHVTVTGECQNCNPDAVYKWDVRADD
NSVFELNEYTTTTGDSSRNLVLRPGALASGHGYTFTLTVTDGSQHGYATLHLDHNDPPSGGLCTVSASEA
KIIASYTTVTFDCSGWNDNNNIYADLLINIIVMRQTGQHTFESFLLYRGTQTTYQSTLPVGLEDWNRNVR
VVILVEDRLGAQAEAFNSTMTVEYPEKTDLNGFDTVVQWLSNRTSTDLQNAEQNGNTQLILGLALISATI
LNVRSEEAWASNANDGEFSDRENLRSDIINTVTSLSGSISTKEDSKQVSAVLSLCTMFPPEMISETSHHG
ITSALEDLVQIQEEEAEEGQVVDMDTATNIMNIISNLMDAANLNIYEPTTDISVSFSESHRREVVTNTYS
LASRYNYALLKSKVEGEEDIVINAPSISSRAKLTQASVVSTAQNISGSQFVVPRSVLGASSEVVSQVEMV
FDTNPFTWGHQHHISSQMMSLQFARSDQTEVSVDNLPEESQIKAFMVEGGLRNTIIGGSLVGSPGYDPSE
GLDTTDGTIKGGGAINVIVNITDCRSALHIQVRYNETVAGSTEEDQSVTAVYVGTNNRTLVLTQALMTGD
HRDYTMFFPPSEHAGMSQVNLTITNNYQKQDVQVSVGLYCSSCLYYNQDTGEWDDAGLTASAESTATVSV
CYTSHLTSFGAVVLLPPNAITLEDFPTLEDIAQNPVALITCMCWLAVFLVAGFVVRKLDLRDIRKVAVVP
LCGRDGPYKYEISVMTGMTRNSGTTAHVGVNIFGSNGKKSGRRVLLKPNAFLRNSTDVFQIAVDGSLGDI
IKIKIWHDNTGLDPSWNLKSLVVHDIQTDKRYHFLANSWFSLEEPDGFVEKDVYVASPDALKKFSTVFKN
ETARGLSEQHLWLSVLERPARNRFTRVQRVTCLATLVYSFMCVNAMWYGLIKTNTEDVEIWYFAFSWEEL
AVGIISNLMVFPINLLIVTLFRKIKSKVKATDYYEPVAQRAQTAQTIEMDVMCATSQNGESLITMSGQSD
PFALSFDPRTGSMKHSQSFRHGGLLDDDDDSDDEAEYRPRGGKMSMVDSWEDLRKDKRSLENRNKLWSYE
SIMNWSDTEQAPSKTKKSQLKRKKTGRYGNGKDIPGIHVDAVLSDDDDDDSWGKTAPTPKIKKSGNFLST
KTQADGKMSRTHSVDDLLTSDEFWSSIMDETSDQKDSSRTLQSSGSFTPRSDADLDSGIGDPIHKTLEPS
IHSESDQSQQTQTFLLESDTTSLDSSVPPQRRRTGRPASSSSVESLDEEKGKWLLPYWFVYIAYLLCAII
IAGCMVVIIMYGQAFGRDQATKWVLSMFLSLIQSMFLMEPIRVILIALFLASISKPTNHDDEDDLVDRPV
VENQDDRTKSKAIRAPYGYGLLQAREEARKVRVMYTIIHQCIFYLLFILTILIIAFNDNDLNTYRMTHSI
EDSLVKPEFGTSNRSFLTITQSEDWWEYMDSVLLPTLLDTSQGPIRDSSLEGVVLGGVRLRQIRNTPETC
MLQGLNRYPNLWTSDWECYYNVRLSTEDSSSYGETWTASQANQANWTYSETNSYNGLMYYGRDGSYSDNG
YILDLPRSYNASITALAALNSSDWIDRGTRAVFVEFSLYNPNVNLFSVVTLLLELPVTGVGRASRDIKSG
RFVVYGYGVDLLMIMQGLFALFLLYYIVVECCQLKRHGFKSYLKRFQTYYEWTIIIISTSSLAVYIHRLM
YTTGLWREHLADKTKFISFFHSAYLGQVTAYLNGLVIFLLMIKVARQMRFRRQFSIFGKALRLVTWELAG
CFLIFFILILTYAQLGYLLFSNHSPYFTNMWMSITAMVAMFRGQVDLDPCREAQPFLAFLFFTSYILVVF
CIVGRLFGAILIHGFTAVRKEMHRPAVERQDYEMVEFMIKRFKMWTGLAKPKAWRHNVKFLGMDRLSTRS
SRSTVTTPGGLSHISTPNSPISLESSGSVGLGHIPEVGQMDPNHLEYLLDRLTPTVDAVLSTFDRLRHYV
DDDNTFDEEPIQPAQRSHQRTNISNETQQKRNINISRKDAQSAPAKSGRSSNRVLKASSSWTQGIPGQEK
ALPTQRENSWTKGSSTSGPPSRRDQSSAWRQNKEVSWADRYKDNAWGSSNWTRKGASDPWGDRRREDSWE
QSHPRSTTNSPARKKEHSWSSDYGSSRRQGSRGSVPQRPTPKKPAW

>Drosophila melanogaster_(FBpp0088744)
MTTNRSTRLLVLLVLTALVASHQAHAAAVGLKCGGKSAVCVGPLSYQQCVDDLTTGPVVP
CALNTRCVTDGLEICVPVKSAAEAPTAAVAKMVTITDSPVVSESAPLVDSTNSGSGVEIS
TEGAPASAVPTKPSIPVETTQAPVETTQIPLETTQVAVETTQIPLETTQASGETTTAAIE
ETTTGSEAPLEPESTVPSDTTPVDSTLAPGWEGTYPTIEPNTPAEDPNAPAGTTLAPGEV
DPNSPIDPNSPLDPNAPEESTNEPGLVDPTLPADTTTAPDSPVEGSSAAPGTPADVTTAA
PGAPADGSSAAPGSPADGSSAAPGSPADVTTAAPGAPADGSSAAPGAPADGSSAAPGSPA
DVTTAAPGAPADGSSAAPGSPAEGSSAAPGAPADVTTAAPGAPADGSSAAPGAPADGSSA
APGSPADVTTAAPGAPADGSSAAPGSPAEGSSAAPGAPADVTTAAPADGSSAAPGSPADV
TTAAPGAPADGSSAAPGAPADGSSAAPGSPADVTTAAPGAPADGSSAAPGSPADVTTAAP
GAPADGSSAAPADGSSAAPGSPADVTTAAPGAPADGSSAAPGSPAEGSPPAGGSPAGSNV
PAGGDPADSNVPAGGAPADSNVPAGGAPADSNVPAGGAPADSNVPAGGAPADANVPAGGA
PADSNVPGGGAPADANVPAGGAPADSNVPAGGAPAGSNVPAGGAPADSNVPAGGAPADSN
VPAGGAPAGSNVPAGSSPGSSVLGPNPPAGSVVPSIPVLPGGAGSWPWHPRPNIPIVPPT
WRPLLPGQNGSGAPGSGLINGIVNPPQRPHPFWPNWQSWVNSWRPTKPVPSTEAPVQPQN
PQQPQNPQQPGNSNPETAESVEQAAPVPPANVPASNENASVEDSNKASSEKSKDKPKSGE
DQSKEQEQKKPSSEEKEKDSKEKNDKDSKEKKDNDSKDKKDKSKEEKDNESQKDNDGDDE
PSSKEKKQYVKDLIKKLKKGDECDEDDVYPDVRDCRKYYRCEVKKSGKHKFAHLRCDKKE
RFDWLTQSCVPKDEARCLEK

>Nematostella vectensis_(XP_001636807)
MLNGSGAMNYTFGAYSSCCYFWDEAGGMWSSQGCEVGRNTSRQVTHCKCSHLTWFGAKLFIPPNAIDLSS
AIKNFANFDESPALLATFCAILGMYLVALIWARRRDLKDTSKVGLVAVPDSDISDLYRYEVTVYTGRGKA
AATTSNVTLIMCGELGESQAVTLTDDNSEVFQAGGIDSFFVTTPNPLGALCYIRIWHDNTGSNPSWYLNQ
VAVRNIDSNERFYFLCYRWFACDEGDGEVDRVLPVAGKEELAQFMYLFRSKATRDFSDAHLWFSIALRPC
RSLFTRTQRVTCCLSLLLCTMLANVLWYQVPQSQKEDVIFESGFIRITWHELLIGIQSSLLVFPINLLII
QIFRNTKPRPLHKDDSCEVKSICSRSVTTPAIALQDITTVTRETPDVVKSWTHSERRLDSPYKQRRGEEK
KNLDTIERPTEQPSPVSIESFDYVDGAKPLFKSPAEANARKSKKAKEHVGKVLLPWWFVYVGWALCLLTA
CTAAFFTMLYGLTFDKPKQHAWLISMFFSLVQDIFISQPLKVLGFALVFALVLKKPQGENDEKLNSELAK
DRQWLEEHVGQRDKRRNAISNDKPKYLPPDPSALQRARLQRFKERKMFEVIQEILFYALFVWVVLVVAYG
HRDPNAHVMNQGLEDVFSGRAKHDHSVPDGHSLLFQVSDITSFWNWTEAVLIPGLYSESWYNGRSDKPGF
LADHTSWMLGTARMRQLRVKAGDCKVHDVYSGYLAQCNGPYSWDTEDTTPVFRPGWRPAPSNYSTAQNAW
KYRDSSELRSLPYLGKLALYSGGGYAFDLGKKEKAMAMLAQLKRDKWVDRSTRAIFVEFTVYSPYTNLHC
VGYLLLEVLPSGGTSPFSELLVTRIDRYAGNFMIFVLLCEILFVLFTVYFTYKQGKEIAREGVAYHFHEY
WSWVELVLSGCSWTSIVLYFVRFGINKSTVLTYHKDTSVFVNFHALAASDQVFGYVYAFVAFFVSLKFLR
LFRFNKRMSLLATTLKCSAKELAHFSIVFGLVFMAFVHFCYLIFSTELYIFHTVLSTVETLISVMLGKFS
YERLLQTNRLLAPFMFFFYSIVVVFILINMFISIIIENFQRVKSQNDLQSNEYEIVDFMTEQFRDWLG

>Amphimedon queenslandica_(XP_003389786)
MSSQVICVSCKYPLIPHDAKFCGKCGAPQSLTKACIHCKAQLSLDAVYCVVCGEPQKQNVTVKRCIHCGA
HLPSIAVYCSKCRQPQASSSQESLKTQCIFCGRALLSPGKDCIFCTAPQDYEELNKRPFKKCQACGRHIF
YESRVCVDKYCSAIQKSPPTSAIHHTIPFTTESQAPSYDVQPQNYSPQLASYATAGPPPAIPHPAGPLAG
LPPSTDPPPADLPPSSDPPPPPPPDLPPSFDPPPPPSADPPLADLPSSSDPSPPADSPPSADLSPLADLP
PPSGLPPPSGLPPSSDPPRPPPPSADPPLANLPSSSDPSPPADSPPSADLSPLADLPPPPTDRPFLSQEQ
IMKKFKQNQSITSDLSAAQTPLDQGNNSASRQKQNSVTTTVVGNTDRVTAMVGGAVTCEKVDDTFGIIGE
PVTVIDITQKSEEEWTILDGDKKNGENNQQSETENLGRENEGTSDNRSNDTEDKLNNINRSNDVMGGSKN
GAIRNTKNGSGNGSNDSRDGDSETDRKQKGKDAKEGENDGAVSERVESAKDEANKKGHKEGIKESGKSGE
NIKGGISGKGVGSSGTVGGNENKPRSEKKDELRVCPNLPTTKLHVLQPTQNRAMRLQFNAVIQKEIWKWE
EGSSEVYMRFGHKSLGDWKFDIGPCILLRDAGGGFHSVRYDMTINTDFIVSLKNGLPYKYVVYSPLIKVT
HQFEYLHGAPPYQGVNTNRLLKVPKEKLVPGGFYRQFDTIILPETKVKTAKGTLKKVWDIISRAEPDDPT
AITVPTPTVMRCQCMEIHLQPTREILLSGKFKVKLDVAINGCVSLIRCAFLQWVEHRGGENRWEVPDIGS
FLIDWIEAVLVNLNKQRDYAYNSVTSAVLLACCLYKLNQSVNVPFSNEFRVALLQAMSLSITNGEKELKF
LRSMIGESPEAKNIVVVALVHYLRTVIALQKHENAIVIVKALPLYHFLCDLSVPNQKSCVPLNQITWGDP
SVMIGKLQSTLQFKSGFVQKHEKDIQQLFQFDSKLLYIIPYICPQEDTVILCDMLPIELAIVWLIERLNL
HSDTHNLRLSSVTENKMNHCFRIPLANILKRIYEKDITTFAVLVWYSDAAGFLLESFRDKLNFSKNAKIL
VKSMISLYLHILFKAKLFQDQANNQDTLCQSLTVNVRELLKDWVAHKDVIGGSFFGASLKFAGTTFQELK
KENEELEFWKSILSLKFSADVMENDLEAIVLELVSDRVSEIPSPELKINLFINVEHRKEIADSFRNIFLT
KAIEALDSMFSKRSMTQSIQRWDTLLDLKSERVFKLISKIIEKRYPEFRRTQEIPFNDLLDWEMWPGILK
ISYAQVGKDTRESGEWRLIVTCAVSKLEAVCANINSGGITITELNSIRAKQIQMNKLCEVIDESRIIDLQ
KSIEKRLKEFEHFEEYMMKLKYFLSHIRKILAGQYNLMDELQKNYEDEKINKLCITASDGSCEVVSFSDA
RPLDPCLNGFFIISSKYSSDIFNRLWHKNMSEQPATVDSSKIYSILWQPTLQSCTLLLKKLQSGDMTLLE
VDDQFKNVYFKKLDKLQKDLINLQHAADAINHIVTDDINWIKNAVVHIGQYWDLCGYRETAESFLKIRDT
LNLTGDFVIVERVASKVSSNHATLSTIDHSVVDAGRFLQEYAMDTAKRECLEAFADCQKIVEWIRNETKD
VTNLVNFVTVALATAAGGEGDMTTDKLSFLRTVGSGFGPLIYRLTKDASYQKLQELCKTLWVTLETAPNL
PEMMRTCEREIDWYQSVKETQGSVEVTSFGQMNNINSYGIYEIGSSKKGILVSRSEGIHLRMRQSKRKRI
HKLHYNLDELRDLESKLVLITGRETKERKQVDLFLDVFHSVCRITDVLIELQQHGNDKYIGWTLTFSCAL
DDIVNCLQVRASALEEDLQTWKCQLAQQRDNFYELNYFTTPQLLSLREELGQFKGSAVPTRPVKQEVLTL
LQSISRELSSNAIKNEVQTVNGILAEQQFLQDQLFTHSKSSQSYLSGYVDPPSRLLSDNALPIQNDHNSF
IPAAELHANRESIGNRDSVPLTKPIVEAVLKTVTPSGPQPKLTDEDLTDNQKAMVYDLKEEFGFSRKLIF
LAFERCEKPKVQEAVMEWCNENIENFDFTDSDAESETATEIYPEDEEELPSEEEDMEIDVEEAITLHEPP
YLPGSYSALEESFDRPVEAWTEVPPLASHTVSHSSHPPASRPARLKVVDRVPISEDHPVVRGLIDSGFTV
EESLAAAEQHPDNIERAMASLMEGPPESGELFAPVPYDSVFERHDSIGEYDRQISADSDELQNLVITSSE
KTSAENYLTILALGMTLQQLSQSNKPTVGLQRKFPEGLKCGEPNLLVTPPGTQNKVFKTVLSLYMETKDL
PMPTYEEVLICNENTTEEERMKEELKSKCYGVSSDVIIPVHGPKVTSDSIVQLLKSSVGSKDTNQAIIFH
LDISPNVLRQVDSVLFSLLILQAVSDSQGKIWRSYISHLYAIEVSVLKNDIKFAKPTVELLKLLPTVQCL
SPRSVCNVLEEGRGDASARLMDEKEFRSSHFQRVYQYLRRHIGSSPLDRFSYNPGLVEGKHVECLQVLLK
QCGVKDPSWSELKHFVEFLNTQLRSCENSIFCNEDIVGDVMSGLKTFVVKFMIRMSKDFATSSLKGEVAA
ENQEEIPVEETLQEYQIDERKQWEQSYHPYLFFNEDGMSITFVGFNVTRTGDLMDPVKGLMIEAGVMKPQ
LHTGLQHNQVNLSENYQSWQKDTMIEKIGMVMGLEWSYDPDPTYVLTVDNVIKIMAIHMRFRCNIPVVIM
GETGCGKTRLIRYMCDLAARGCKDGGSHVQNMLIMKVHGGTLESDVIKKVEEAEKIAAKNRNDHEIDTIL
FFDEANTSDAIGLIKEVMCDRRINGRLIEADVKFIAACNPYRKCQDVLLDNMKLGPNIARNAALRENVFM
MAICIELRIPLFLVGKPGSSKSLAKSIVAASMLGRSSEKQLMKEFKEVHMFSYQCSQLSTPESVIEVFNT
AKSFQKKQDVTNYVSVVVLDEVGLAEDSPNLPLKALHPLLEDGTEGADDSEQQRVAFIGISNWALDPAKM
NRGVMVTRGDPDEKELELSARGICSNRVDDPVKERLDAYFQPLSAAYKKICDEQAKVNKAFFGLRDFYSL
IKMLYWMCEKSGRPPTGPQLQHAIKRNFGGLEDFKTYEIFKNLLPNIDKVPEPSSVQQDNELLNPDCTPL
GLIRKSLQTKETSWHGENRYLLFLTENYAALQVINEHRIEPFVLFGSSFPKDREYTQVCRNINQIKICME
TGRTVILLNLENLYESLYDLLNQYYIILAGGQRYVDLGLQTHRVKCRVHNNFKLILIAEKSTVYEKFPTP
LINRLEKHFVLTETVLQEEWQKEVHMRLNYWVEQFSKINHTNKKFTKQDAFVGYHDDTPSSVIFQATEQL
HSIQSWKKNFDWNEHHKTDEWKRDVLIFSKKVLLQMASPDALIRLHNTSLSDQQKKLKNIYFNEQCHGSI
VQFLQYHLHGGQAHQSGLLIQVTTHSHLLSSLEVKDLCFKIELEYDCVSCFLLQEFDTEMDFSNKISPTF
TRDSHGTDKDYLLIIQCDSGHLYGDLLACARYRIDDERAKLKWREGQGSTHVLFVIHLPRQAETQKSSFV
GFQGGSWISAHIDDIRAPTESALTLDDALSSPISQLFYSRRFESEPEPSASIEEPMETYEEERMGLEDEE
ELMENEADHDVLDDLPFVKPSYQAPQSKGDHTQCCRLRTSVQATVAKLVESDETRRQWGAHRLKLLLELI
PQRPIFPLSSDTFYGALVKHIKNLLEEREKNSLYKEWVLNEALSTEKLQSGGTFQNVLTRRLDEVIVPLF
ADILLFVDHYSNLNLLKEARDYVEQLWLAIFSNEELVLFSYQSYAMGKGIHELQPTTTGVIGGRVLAADE
EFVCCFPFFWLIKEAIEAKLDTVRTSSSGSRQDIHIQLCEVLSETQLAIILKRVPEENWNEMYWYYLGDI
LRSIHHVPHHRASDEYEIITKALDAIITGPEFTHQSLMSYLAAVHVVYHDYQQEMMWFGQLTTHIPGILV
HLKNAIEVHNLQYMDLPLHAVSVAIKHELSLPLKPEDREYIPQRLVKLQLCQNAINSIISLGLNAPNEQS
KELCIGIKCKWQHVRAIQMFVEHIVTKFSTDDKKFENLVKYGTRIELFLKNCQEFTRVQAIQKVQTVLRT
LDSDAVKKFKFSADLQKRIRGYCKAFFMEVVSSLCFGQTTPPEPQLIEELLKVVFTEKDKTKELTYSDKE
ETDAVPVIRSFLLQLLLEHNIDAVREHLEVYFSRSRQLIKDDRNLCLLCIQCFEDSVHKRYIEASLQERV
ATAYELLKDGGTVVLSAPAPSLEGGITLPYLEGIAKIRYSLSIVAELLHCQNSGERQCLHTNYSRLLLEM
AKRCCEDVKLNYNETDKDSGPGVFLVKQLARQYGVTFLTNVTSEEEMKWIIPINLRQEETGHNDPFVIYQ
DYKKIRACLSDAVYGENLEELTLAIQNLSDAEVIPLLVGVYEIVTGSNTFTTEAKRISGETKEGILAAVR
QCKRLKRELMWAAQHLINDSYCGTLEPMTLRPGINPQNRLLTDLVVHAAIIIQSSNKKLVTPFVQMINSP
AELKRVYMPTMPEDILPLVKGAVGGGQFYECPRGHRYFISECGRAWTESTCPECHAPIGGKLHVLIADNK
LSNNTDNTETGYALGNPTQREAVPSTERALSPSSCAILRAIMHCSLLWSSCTNEHATEGLLDLTKEQVRP
ADMPTFFWEHLMHDIHMLSTAIGKSRDDSCLLMHLILRNIASQNTAIPIAPGLDSREYRAEWERCFSDTF
IKPVLMNLDAELQQATRLLLSDKKEECDHLFYVIHERVRLSPKAITPHLWSYRSRITLEHLLQVLQTRKE
RYSILYEFVIQEPLLRATQYLPAIVKLQQEMYRLSHRRLDKNEVAKITIGNYVDSLKEYRGIHNENKKNQ
FQEKLNCVRKAWALVKERLKDHSRVPVDLEFVRTLTWDDSTPLSYLIPTLTGHGVCTVALVDLLVAVHND
FVEKCHSQLKKKQKKEILWKKHKVPASQIQSCHLLDYEHQILSIVLSHCHYSLEHGKGQNVSYDLQALEK
NIVDRFIHGKPLVLLEIPQVVYRKDVYTAKAFASIRKNIKPQVKLNTKQQTEIVTELGSMQRLRECLDVV
EIVISFLSSEKRGGTANIELKGYVKKVLRMEKKFTSKKAMEYCTLGHILSLWETISVRMAKTLTLRKQEP
FDSLDQEFYEKLQEEQERELKSFLRGVDIPPFLNLFFEFIETNVRHREAHERNWPLRDTMYAHLESYELE
KELPNGFEDNFPDTITLKQSVATWEIIVFHQERHEQEINEQ