>Homo sapiens_PDE5A(ENSP_347046)
MERAGPSFGQQRQQQQPQQQKQQQRDQDSVEAWLDDHWDFTFSYFVRKATREMVNAWFAE
RVHTIPVCKEGIRGHTESCSCPLQQSPRADNSAPGTPTRKISASEFDRPLRPIVVKDSEG
TVSFLSDSEKKEQMPLTPPRFDHDEGDQCSRLLELVKDISSHLDVTALCHKIFLHIHGLI
SADRYSLFLVCEDSSNDKFLISRLFDVAEGSTLEEVSNNCIRLEWNKGIVGHVAALGEPL
NIKDAYEDPRFNAEVDQITGYKTQSILCMPIKNHREEVVGVAQAINKKSGNGGTFTEKDE
KDFAAYLAFCGIVLHNAQLYETSLLENKRNQVLLDLASLIFEEQQSLEVILKKIAATIIS
FMQVQKCTIFIVDEDCSDSFSSVFHMECEELEKSSDTLTREHDANKINYMYAQYVKNTME
PLNIPDVSKDKRFPWTTENTGNVNQQCIRSLLCTPIKNGKKNKVIGVCQLVNKMEENTGK
VKPFNRNDEQFLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEETREL
QSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWIL
SVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGV
NNSYIQRSEHPLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAI
LATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAE
LVATEFFDQGDRERKELNIEPTDLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCF
PLLDGCRKNRQKWQALAEQQEKMLINGESGQAKRN
>Macaca mulatta_PDE5A(ENSMMUP_9576)
MERAGLSFGRQRQQQQPQQQKQQQRDQDSVEAWLDDHWDFTFSYFVRKATREMVNAWFAE
RVHTIPVCKEGIRGHTESCSCPLQQSPRADNSAPGTPTRKISASEFDRPLRPIVVKDSEG
TVSFLSDSEKKEQMPLTPPRFDHDEGDQCSRLLELVKDISSHLDVTALCHKIFLHIHGLI
SADRYSLFLVCEDSSNDKFLISRLFDVAEGSTLEEASNNCIRLEWNKGIVGHVAALGEPL
NIKDAYEDPRFNAEVDQITGYKTQSILCMPIKNHREEVVGVAQAINKKSGNGGTFTEKDE
KDFAAYLAFCGIVLHNAQLYETSLLENKRNQVLLDLASLIFEEQQSLEVILKKIAATIIS
FMQVQKCTIFIVDEDCSDSFSSVFHMECEELEKSSDMLTREHDTNKINYMYAQYVKNTME
PLNIPDVSKDKRFPWTTENTGNVSQQCIRSLLCTPIKNGKKNKVIGVCQLVNKMEENTGK
VKPFNRNDEQFLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEETREL
QSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWIL
SVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGV
NNSYIQRSEHPLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAI
LATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAE
LVASEFFDQGDRERKELNIEPTDLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCF
PLLDGCRKNRQKWQALAEQQEKMLINGESGQAKRN
>Mus musculus_PDE5A(ENSMUSP_69011)
MERAGPNSVRSQQQRDPDWVEAWLDDHRDFTFSYFIRKATRDMVNAWFSERVHNIPVCKE
GIRAHTESCSCSLQQSPHADNTTPGAPARKISASEFDRPLRPIVVKDSEGTVSFLSDSGK
KEQMPLTPPRFDSDEGDQCSRLLELVKDISSHLDVTALCHKIFLHIHGLISADRYSLFLV
CEDSSKDKFLISRLFDVAEGSTLEEASNNCIRLEWNKGIVGHVAAFGEPLNIKDAYEDPR
FNAEVDQITGYKTQSILCMPIKNHREEVVGVAQAINKKSGNGGTFTEKDEKDFAAYLAFC
GIVLHNAQLYETSLLENKRNQVLLDLASLIFEEQQSLEVILKKIAATIISFMQVQKCTIF
IVDEDCPDSFSRVFHMECEEVGKPSDPLTREQDANKINYMYAQYVKNTMEPLNIPDVTKD
KRFPWTNENMGHVNTPCIGSLLCTPIKNGKKNKVIGVCQLVNKMEENTGKIKAFNQNDEQ
FLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEETRELQALSAAVVPS
AQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNV
AYHNWRHAFNTAQCMFAALKAGKIQNKLTDLETLALLIAALSHDLDHRGVNNSYIQRSEH
PLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIDEYKTTLKIIKQAILATDLALYIK
RRGEFFELIRKNQFSFEDPLQKELFLAMLMTACDLSAITKPWPIQQRIAELVAAEFFDQG
DRERKELNMEPADLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCLPLLDGCRKNR
QKWQALAEQQEKMLLNGESSQGKRD
>Felis catus_PDE5A(ENSFCAP_9620)
MVNAWFAERVHTIPVCKEGIRSHTESCSCPSQQSPRADSSAPGTPTRKISASEFDRPLRP
IVVKDSEGTVSFLSDSEKKEQMPLTPPRFDNDEGDQCSRLLELVKDISSHLDVTALCHKI
FLHIHGLISADRYSLFLVCEDSSNDKFLISRLFDVAEGSTLEEASNNCIRLEWNKGIVGH
VAAFGEPLNIKDAYEDPRFNAEVDQITGYRTQSILCMPIKNHREEVVGVAQAINKRSGNG
GTFTEKDEKDFAAYLAFCGIVLHNAQLYETSLLENKRNQAKVLLDLASLIFEEQQSLEVI
LKKIAATIISFMQVQKCTIFIVDEDCSDSFSSVFHMECEELEKSSDTLTRERDANRINYM
YAQYVKNTMEPLNIPDVSKDKRFPWTNENTGSVSQQFIRSLLCTPIKNGKKNKVIGVCQL
VNKMEENTGKVKPFNRNDEQFLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHA
SAAEEETRELQSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQM
KHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLETLALLIAA
LSHDLDHRGVNNSYIQRSEHPLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYK
TTLKIIKQAILATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITK
PWPIQQRIAELVATEFFDQGDRERKELNIEPADLMNREKKNKIPSMQVGFIDAICLQLYE
ALTHVSEDCFPLLDGCRKNRQKWQALAEQQEKMLINGESSQAKRN
>Gallus gallus_PDE5A(ENSGALP_19524)
MERSCHPSPEQEAVEAWLDDHCDFTRSYFVRKATREMVNAWFAERVHTIPVCKEGTKSQS
ESCACQQLACSENTNSGTPARKISASEFDRPLRPIFVKDSVGAVSFLSGSEKKEQMPLQS
PRTGTSAGDRCSRLLELVKDISSHLDVTALCHKIFLHIHELIAADRYSLFLVCEDSSNEK
FLVSRLFDVAEGSTLEEASNNCIRLEWNKGIVGHVAAIGQPLNIKNAYEDPRFNAEVDQI
TGYKTQSILCMPIKNHREEVVGVAQAINKKSGTGGTFTEQDEKDFAAYLAFCGIVLHNAQ
LYETSLLENRRNQVLLDLASLIFEEQQSLEVILKKIAATIISFMQVQRCTIFIVDEDCTD
SFSSVFHMEAEELEDSAENQKRDCDTNKINYMYAQYVKNTMEPLNIPDVCKDRRFPWTTD
SAESVSQHIKSLLCTPIKNGKKNKVIGVCQLVNKMEENSGKIKAFNRNDEQFLEAFVIFC
GLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEESRELQVTAAAVVPSAQSLNLTDF
NFSDFELSDFETTLCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAF
NTAQCMFAALKSGKIQSKLTDLETLALLIATLSHDLDHRGVNNSYIQRSEHPLAQLYCHS
IMEHHHFDQCLMILNSPGNQILSSLSIEEYKATLKMIKQAILATDLALYIKRRGEFFELL
RKKQFNWEDPMQKELFLAMLMTACDLSAITKPWPVQQRIAELVATEFFDQGDKERKELNI
EPTDLMNREKKNKIPSMQVGFIDAVCLQLYEALTHVSEACYPLLDGCRKNRQKWQSLAEQ
QEKNLINGESNQAKRN
>Anolis carolinensis_PDE5A(ENSACAP_13103)
KAWILLFWDFLLNLLRERRGREMVNAWFSERVHTIPVCKEGTKTHSETCSCSTLQTTRSE
NTNSTPPARKISASEFDRPLRPIVVKDSIGTVSFLSDSEKKEQMPLQSRTLRTDAGDQCT
RLLELVKDISSHLDVTALCHKIFLHIHELIAADRYSLFLVCEDSSNEKFLVSRLFDVAEG
TTLEEASNNCIRLEWNKGIVGHVAALGQPLNIKDAYEDPRFNAEVDQITGYKTQSILCMP
IKNHREEVVGVAQAINKKSGGGGTFTEQDEKDFSAYLAFCGIVLHNAQLYETSLLENRRN
QVLLDLASLIFEEQQSLEVILKKIAATIISFMQVQQCTIFIVDEDCSDSYSSVFHMEFEE
LEDSNETHKRDYDTNQINYMYAQYVKNTMEPLNIPNIRQDKRFPWTPFNVNNVNAQKVCP
KQLLLTTEKELGEKNETPNDPGVCQLANKMEENSCKIKAFNRNDEQFLEAFVIFCGLGIQ
NTQMYEAVERAMAKQMVTLEVLSYHASAADEEARELQVTAAAVVPSAQSLGLTDFYFSDF
ELSDMETSLCTIRMFTDLNLVQNFQMKHEVLCRWILSVRKNYRKNVAYHNWRHAFNTAQC
MFAALKSGKIQNKLTDTEVLSLLIAALSHDLDHRGVNNSYIQRSEHPLAQLYCHSIMEHH
HFDQCLMILNTPGNQILSGLSVEEYKATVKMIKQAILATDLALYIKRRGEFFDLLRKKQF
NLEDPYQKELFLAMLMTACDLSAITKPWPVQQRKTQIAELVAAEFFDQGDKERQELNIEP
TDLMNREKKNKIPSMQVGFIDAICLQLYEALTHISEACYPLLEGCRKNRQKWQALAEQQE
NNLINGESNQPKRN
>Xenopus tropicalis_PDE5A(ENSXETP_8757)
QVVGVAQAINKKSGSNGTFTDQDEKDFAAYLAFCGIVLHNAQLYETSLLENRRNQVLLDL
ATLIFEEQQSLEVILKKIAATILSFMQAQRCTIFIVDEDSPDTFSSVFHMESDELEESAD
AVKREYDVSKMNYMYAQYVANTMEAINIPDICKDTRFPWTNGNEEKNFKHIQSLLCSPIK
NAKKNKVIGVCQLVNKVDENSGKIKAFNKNDEQFLEAFAIFCGLGIQNTQMFEVVERAMA
KQMVTLEILSYHASAAEEETMELQVTAGAIVPSAQSLKLTEFYFSDFELSDMETTLATSR
MFTDLNLVQTFQMKYEKTLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALRTGKIQG
KLNDLEILALMIATLSHDLDHRGVNNSFIQRSEHPLAQLYCHSIMENHHFDQCLMILNSQ
GNQILSGLSVQDYKTVLKMIKQAILATDLALYIKRRSDFFELVNKKKFKWDDPSQKELFL
AMLMTACDLSAITKPWPVQQRIAELVASEFYDQGDKERRELNIEPIDLMNREKKDKIPSM
QVGFIDAVCLELYEALTQISESCYPLLDGCQRNRQMWQILAEQQEKNLVNGAKSQPEVKC
NMD
>Danio rerio_PDE5A(ENSDARP_68115)
MEVYPSDSERMMEAWLDDNLEFAHSYFVRKASREMVNAWFAERVHSIQPSREPSKAVPEP
VTAVHSLGPTDVVPSSSPAPSTPTRKISASEFDRPLRPIVVKDAEGSFTFLSDTERVQMP
LPPSQRPGSDNGTDEGGGIRDRGNGDRCARLLELVRDVSSHLDLTALCHKIFLHTHELIA
ADRYSLFLVGEDSSNRKFLVSRLFDVAEGSTLEESSNSGIRLEWNKGIVGYVAATGQPLN
IKNAYEDSRFNAEVDQITGYKTQSILCLPIKNHRDEVVGVAQAINKKCGENSTFTEQDEK
DFSSYLAFSGIVLHNAQLYETSQLENRRNQVLLDLASLIFEEQQSLEVLLRKTVATILSF
MQAQECTVFISDRETANTFASVFHMEYEEIAGSTDFPNRECDVNKINYMYAQYVKNTMET
LNITDTTKDQLFSWTSEDPQSTNCQIKSLLCTPIRNGKKDKVIGVCQLVNKMDEASGEVK
AFNRNDEQFLEAFAVFCGLGIQNTQMYEAVERAMAKQEVTLEVLSYHASAAEEETRALQV
TAAATIPSAQSLRLMDYSFSDFDLTDAETTQATIRMFVDLKLVQNFQIKYKSLCQWILSV
KKNYRKNVVYHNWRHAFNTSQCMFAVLKSGRVQNNLSDLETLALMIATLSHDLDHRGVNN
SYIKRSDHPLAQLYCHSTMEHHHFDQCLMILNSPGNQILSGLSLDEYKATLKMIEKAILA
TDLAVYMKKRTEFFELAKNSQFEWEDDCHRDLLRSMLMTACDISAITKPWPVQKKIAELV
ATEFFEQGDKERRELNIEPIDLMNREKQDKIPSMQVSFIDAICTQLYEALTGISEFCSPL
LEGCRKNRQNWKILAEQGEEAALLNGEL
>Takifugu rubripes_PDE5A(ENSTRUP_25606)
ESERMEAWLDDHLEFTRSYFIRKASREMVNAWFAERVHSIHPSAPKENPPQHPRTQQSSA
DSAVTAPSPVPGTPTRKISASEFDRPLRPIVVKDAEGSLTFLSDADRETVPVRAAAMGEG
GGVHVGGCDEAGSWCGRDRCARLLELVKEVSSHLDVTALCHKIFLHINELIAADRYSLFL
VGEDSSNRKFLVSRLFDVAEGSTVEESSSSCIRLEWNKGIVGHVAATGQPLNIKNAYEDS
RFNAEVDLITGYKTHSILCLPIKNHRDEVVGVAQAINKKSGDDAAFTDQDEKDFSAYLAF
SGIVLHNAQLYETSQLENRRNQVLLDLASLIFEEQQCLKVLLRKFAGTILSFMQAQACTV
FIADEDSMNSFSSVFHMEYEELGEVLDVPKRDCDVSQINYMYAQYVKNTMQTLNIADVTK
DQRFPWTGENPDHTNDQIKSLLCTPIRNGKKDKVIGVCQLVNKMDEASDSVKAFNRNDEQ
FLEAFAIFCGLGIQNTQMYETVERAMAKQEVTLEVLSYHATASEEESRELQVTVVATVPS
AQSLRLLDFSFSDFELSDTETTLATIRMFVDLNLVQNFQMKYMNLCRWVLSVKKNYRKSV
AYHNWRHAFNTAQSMFALLKSGRLQNNLNDLEVLALMIATLSHDLDHRGVNNSYIQRSDH
PLAQLYCHSTMEHHHFDHCLMILNSPGNQILSSLSLDEYKSTLKMIERAILATDLALYMK
RRGEFFELTKNSQFVWEDEQHRDLLRSMLMTACDISAITKPWPVQQRIAELVATEFFEQG
DKERRELNIEPSDLMNREKKDKIPSMQVSFIDAICTQLYETLAGMSEYCSPLLEGCQKNR
QQWKHLAEECEKGLVNG
>Oryzias latipes_PDE5A(ENSORLP_25741)
SLCQWILSVKKNYRKSVAYHNWRHAFNTAQCMFALLKSGRLQNNLSDLEILALMIATLSH
DLDHRGVNNSYIQRSEHPLAQLYCHSTMEHHHFDQCLMILNTPGNQILSGLSLDEYKATL
KMIEKAILATDLALYMKKREDFFELTKNNQFVWVDEHHRDLLRSMLMTACDISAITKPWP
VQKRVAELVATEFFEQGDKERRELNIEPTDLMNREKRDKIPSMQVSFIDAICIQLYETLA
GLLEHCSPLLEGCQKNRQHWKRLAEDCEK
>Homo sapiens_PDE6B(ENSP_420295)
MSLSEEQARSFLDQNPDFARQYFGKKLSPENVAAACEDGCPPDCDSLRDLCQVEESTALL
ELVQDMQESINMERVVFKVLRRLCTLLQADRCSLFMYRQRNGVAELATRLFSVQPDSVLE
DCLVPPDSEIVFPLDIGVVGHVAQTKKMVNVEDVAECPHFSSFADELTDYKTKNMLATPI
MNGKDVVAVIMAVNKLNGPFFTSEDEDVFLKYLNFATLYLKIYHLSYLHNCETRRGQVLL
WSANKVFEELTDIERQFHKAFYTVRAYLNCERYSVGLLDMTKEKEFFDVWSVLMGESQPY
SGPRTPDGREIVFYKVIDYVLHGKEEIKVIPTPSADHWALASGLPSYVAESGFICNIMNA
SADEMFKFQEGALDDSGWLIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDEQDEVLMES
LTQFLGWSVMNTDTYDKMNKLENRKDIAQDMVLYHVKCDRDEIQLILPTRARLGKEPADC
DEDELGEILKEELPGPTTFDIYEFHFSDLECTELDLVKCGIQMYYELGVVRKFQIPQEVL
VRFLFSISKGYRRITYHNWRHGFNVAQTMFTLLMTGKLKSYYTDLEAFAMVTAGLCHDID
HRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKFLLSEETLNIYQNLNRRQHEHVIHLM
DIAIIATDLALYFKKRAMFQKIVDESKNYQDKKSWVEYLSLETTRKEIVMAMMMTACDLS
AITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQPIPMMDRNKAAELPKLQVGFIDFVCT
FVYKEFSRFHEEILPMFDRLQNNRKEWKALADEYEAKVKALEEKEEEERVAAKKVGTEIC
NGGPAPKSSTCCIL
>Macaca mulatta_PDE6B(ENSMMUP_40713)
MSLSEEQARSFLDQNPDFARQYFGKKLSPENVAAACEDRCPPDCNSFRELCQVEESEALL
ELVQDMQENINMERVVFKVLRRLCTLLQADRCSLFMYRQRNGVAELATRLFSVQPDSVLE
DCLVPPDSEIVFPLDIGVVGHVAQTKKMVNVKDVAEQCPHFSSFADELTDYKTKNILATP
IMNGKDVVAVIMAVNKLNGPFFTSEDEDVFLKYLNFATLDLKIYHLSYLHNCETRRGQVL
LWSANKVFEELTDIERQFHKAFYTVRAYLNCERYSVGLLDMTKEKEFFDVWPVLMGESQP
YSGPRTPDGRELGHSPLHTHVQPGLVPLTPAHTTPPADHWALASGLPSYVAESGFVSPVL
SGAPTALPSLGEGALDDSGWLIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDEQDEVLM
ESLTQFLGWSVMNTDTHDKMNKLENRKDIAQDMVLYHVKCDRDEIQLILPTRARLGKEPA
DCDEDELGEILKEELPGPTTFDIYEFHFSDLECTELDLVKCGIQMYYELGVVRKFQIPQE
VLVRFLFSISKGYRRITYHNWRHGFNVAQTMFTLLMTGKLKSYYTDLEAFAMVTAGLCHD
IDHRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKFLLSEETLNIYQNLNRRQHEHVIH
LMDIAIIATDLALYFKKRAMFQKIVDESKNYEDKKSWVEYLSLETTRKEIVMAMMMTACD
LSAITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQPIPHVDQNKAAELPKLQVGFIDFV
CTFVYKEFSRFHEEILPMFDRLQNNRKEWKALADEYEAKVKGVGRGHTKQEGTNRAVGTE
ICNGGPAPKSSTCCIL
>Mus musculus_PDE6B(ENSMUSP_31456)
MSLSEEQVRSFLDGNPTFAHQYFGKKLSPENVAGACEDGWLADCGSLRELCQVEESAALF
ELVQDMQESVNMERVVFKILRRLCTILHADRCSLFMYRQRNGIAELATRLFSVQPDSLLE
DCLVPPDSEIVFPLDIGIVGHVAQTKKMINVQDVAECPHFSSFADELTDYVTKNILSTPI
MNGKDVVAVIMAVNKLDGPCFTSEDEDVFTKYLNFATLNLKIYHLSYLHNCETRRGQVLL
WSANKVFEELTDIERQFHKAFYTVRAYLNCERYSVGLLDMTKEKEFFDVWPVLMGEAQPY
SGPRTPDGREIVFYKVIDYILHGKEDIKVIPTPPADHWALASGLPTYVAESGFICNIMNA
SADEMFNFQEGPLDDSGWVIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDDQDEVLMES
LTQFLGWSVLNTDTYDKMNKLENRKDIAQDMVLYHVRCDKDEIQEILPTRDRLGKEPADC
EEDELGKILKEELPGPTKFDIYEFHFSDLECTELELVKCGIQMYYELGVVRKFQIPQEVL
VRFLFSVSKAYRRITYHNWRHGFNVAQTMFTLLMTGKLKSYYTDLEAFAMVTAGLCHDID
HRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKFLLAEESLNIYQNLNRRQHEHVIHLM
DIAIIATDLALYFKKRTMFQKIVDESKNYEDKKSWVEYLSLETTRKEIVMAMMMTACDLS
AITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQPIPMMDRNKAAELPKLQVGFIDFVCT
FVYKEFSRFHEEILPMFDRLQNNRKEWKALADEYEAKVKALEEEKKKEEDRVAAKKVGTE
VCNGGPAPKSSTCCIL
>Felis catus_PDE6B(ENSFCAP_7623)
MSLSGEQVQQFLDQNPSFADEYFGKKLSPENVAGAHEDGQPVDCASFRELCQVEESTALF
ELVQDMQESVNMERVVFKILRRLCTILHADRCSLFMYRQRNGVAELATRLFSVQPGSVLE
DCLVPPDSEIVFPLDIGVVGHVAQTKKMVNIKDVTECPHFSSFADELTDYVTKNILATPI
MNGKDVVAVIMAVNKLDGPCFTSEDEDVFLKYLNFGTLNLKIYHLSYLHNCETRRGQVLL
WSANKVFEELTDIERQFHKAFYTVRAYLNCDRYSVGLLDMTKEKEFFDVWPVLMGEAQPY
SGPRTPDGREIVFYKVIDYILHGKEDIKVIPTPPADHWALASGLPTYVAESGFICNIMNA
PADEMFKFQEGPLDDSGWTIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDEQDEVLMES
LTQFLGWSVLNTDTYDKMNKLENRKDIAQDMVLYHVRCDKDEIQLVLPTRERLGKEPADC
EEDELGTILKEVLPGPNKFDIYEFHFSDLECTELELVKCGIQMYYELGVVRKFQIPQEVL
VRFLFSVSKGYRRITYHNWRHGFNVAQTMFTLLMTGKLKSYYTDLEAFAMVTAGLCHDID
HRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKFLLSEETLNIYQNLNRRQHEHVIHLM
DIAIIATDLALYFKKRTMFQKIVDESKNYEDRKSWVEYLSLETTRKEIVMAMMMTACDLS
AITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQPIPMMDRNKAAELPKLQVGFIDFVCT
FVYKEFSRFHEEILPMFDRLQNNRKEWKALADEYEAKVKALEEEKQQQEERTTVKKGGTE
ICNGGPAPKSSTCCIL
>Gallus gallus_PDE6B(ENSGALP_32161)
MSISEDDVEKFLDGNPAFAKQYFEKKLKTESCDDNESEILFELIQDMQESINMEKVVFKT
LRRIRSLIHADRCSLFMYRQRNGTPELATRLFNIQEGSTLEECLVSPDCEIVYPLDLGIV
GYVAQTKKTMNIKDVSECPQFSSFVDELTDYTTKSILATPILNGKDLVAVILAINKLNGP
FFTNSDETLFLKYLNFASLNLKIYHLSYLHNCETRRGQVLLWSANKVFEELTDIERQFHK
AFYTVRAYLNCDRYSVGLLDMTKQKEFFDLWPVLLGEVPPYSGPRTPDGREIVFYKVIDY
ILHGKEDIKVIPNPTPDHWALVTGLPTYVAESGFICNIMNAAADEMFNFQEGPLDESGWT
IKNVLSMPIVNKKEEIVGVVTFFNRKDGKPFDEQDETLMESLTQFLGWSVLNTDTYDKMN
KLENRKDIAQDMVLYHVKCDKDEIQEILPTREKLGKEPSECEEEELASILKEQLPGPTKF
EIYEFRFSDFDCTELELVKCGIQMYYELGVVKKFQIPQEVLVRFVYSVSKGYRKITYHNW
RHGFNVAQTMFTLLMTGKLKRYYTDLEAFAMVTAALCHDIDHRGTNNLYQMKSQNPLAKL
HGSSILERHHLDFGKFLLSEESLNICQNLNRRQHEHMIHLMDIAIIATDLALYFKKRTMF
QKIVDESKTYDNTTAWTDYLSLETTKKEVVMAMMMTACDLSAITKPWEVQSKVALLVAAE
FWEQGDLEISVLQQQPIPMMDRRKAAELPKLQVGFIDFVCTFVYKEFSRFHEEIQPMLDG
LLNNRNEWKTRADEYDAKMKALEEEKKKEEEKMAAQKDGITCNGGTAPTSKTCSIL
>Anolis carolinensis_PDE6B(ENSACAP_1148)
MSVNKDEVETFLDNNLDFAKQYFERKLGDKTLCATASFHQCSEDGVDFGGLGQNETETLF
ELIQDMQESINMEKVVFKTLKRISVLIQADCCSLFMYRQRNGTPELATRLFNIRKDSTME
ESLVAPDCEIVFPLDMGIVGYVAQNKKTVNIQNVDECDYFSTFVDELTGYTTRNVLATPI
MNGKEVVAVIMAVNKSGAQFFSSADENLFLKYLNFAALNLKIYHLSYLHNCETRRGQVLL
WSANKVFEELTDIERQFHKAFYTVRAYLNCDRYSVGLLDMSKQKEFFDLWPVLMGEVPPY
SGPRTPDGREIAFYKVIDYILHGKEDIKVIPNPKPEHWALVSGLPTYVAETGFICNIMNA
ASDEMFAFQEGPVDESGWVIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDEQDEILMES
LTQFLGWSVLNTDTYDKMNKLEYRKDIAQDMVLYHIKCDKNEIQAILPTREKLGKEVSEC
DEEELAAILKEQLPDPEEYEIYHFHFSDLEWTEFDLVKCGIQMYYELGVVKKFQIPQEVL
VRFIFSVSKGYRKITYHNWRHGFNVAQTMFTLLMTGKLKQYYTDLEALAMVTAALCHDID
HRGTNNLYQMKSQHPLAKLHGSSILERHHLEFGKFLLSEESLNIYQNLNRRQFEHVNNLM
DIAIIATDLALYFKKRTMFQKIVDESKTYDNEKEWAEYLSLEATKKEIIMAMMMTACDLS
GIAKPWEVQSKVALLVAAEFWEQGDLEISVLQQQPIPMMDRRKAAELPKLQVGFIDFVCT
FVYKEFSRFHPQIQPMYERLLNNRKEWKALADDYDANMKALEEKRKEEEAKTVNSKGAIL
TCNGESVPPSSTCCII
>Danio rerio_PDE6Ba(ENSDARP_123023)
MSVKKEDVEKFLDGNPDFTKTYFDKKLKPGAVASIMRVPESKVDMDSFKEIVSVEEGAIF
YDLITDMQENVNMEKVIFKILKRISALIHADRCSLFMYRQRNGIAELATRLFNVNKDSEL
DDCVVAPDSEIVFPLDIGIVGHVAQTKKQVNVKDVTQDSHFSTFVDELTEYTTHNLLAAP
IMNGKDVVAVIMAVNKTTGPHFTDEDMDLFLKYLKVGSLNLKIFHLSYLHNCETRKGQLL
LWSANKVFEELTDIERQFHKALYTVRAYLNCDRYSVGLLDMTKEKEFFDIWPVLMGEQPP
YSGPVTPDGREIIFYKVIDYILHGKEDIKVIPNPTADHWALASGLPTYVAESGFICNIMN
AASEEMFKFQTEALDDSGWTIKNVLSLPIVNKKEEIVGVATFYNRKDGKPFDEHDEQLME
ALTQFLGWSALNTDTYDKMNKLENRKDIAQDMVLYHVKCRDDEIQDILKTREYFDREPRD
CEEEELLEILKKELPGPKKFEIYAFHFSDFDCTELQLVMCGIQMYYEVGVVKKFQVPQEV
LVRFMYSVSKGYRRITYHNWRHGFNVGQTMFTLLTTGKLKQYYTDLEVMAMITAGFLHDI
DHRGTNNLYQVKSQNPLAKLHGSSILERHHLEFGKFLLGEESLNIFQNLNRRQTEHVFHL
IDIAIIATDLALYFKKRTMFQKIVDLSETYEERKKWIDFMSLETTRKEIVMAMMMTACDL
SAITKPWEVQSKVALSVAAEFWEQGDLERTVLEQQPIPMMDRNKAAELPKLQCGFIDFVC
TFVYKEFSRFHPEIKPMFDGILNNRMHWKERQEEYEAKLKAMEEAVKARQEAAAKNAANS
NSTGGSGSKTCSIC
>Danio rerio_PDE6Bb(ENSDARP_392)
MAAVDKDVAEKFLDSNPMFAKQYYDSRFRAKVVSDLLSTTKQTAVDISSHHELSSMEECE
IIFDMVRDMQENLHMERAVFNLMRHLSFMIRADRMSLFMYRQRNGIAELATRIFNVHKDA
TLEECLVPPDSEIVYPLDTGIVGHVATAKKTVNVPDVTKDSHFSDFVDNLTEYETKNVLA
TPIMNGKDMVAVMMAVNKIGAPHFTAQDEETLKKYLNFANLVLRVFHLSYLHNCETRRGQ
VLLWSASKVFEELTDIERQFHKALYTVRAFLNCDRYSVGLLDMTKTKEFFDLWPVLMGEV
PPYSGPKTPDGREVIFYKVIDYILHGKEDIKVIPNPPADHWALVSGLPTYVAENGLICNI
MNAAQDEFFEFQKEPLDESGWMIKNVLSLPIVNKKEEIVGVATFYNRKDGKPFDEMDETL
MESLTQFLGWSVLNTDTYDKMNKLENRKDIFQDMVMYHVKCRKDEIQNILNTREMYDKEP
DECEEDELEDILNEVLPDSEESEIFEFHFCDFEFSELDLVKCGIKMYYELGVVDKFHIPR
ETLVRFVYSVSKGYRKITYHNWRHGFNVGQTMFTLLMTGDLKRYYTDLEAMAMVTAGLCH
DIDHRGTNNLYQMKSGNPLAKLHGSSILERHHLEFGKTLLRDEALNIYQNLNRRQHETVI
HLMDIAIIATDLALYFKKRTMFQKIVDQSKTYDSWDSWTKYMMLETTRKEIVMAMMMTAC
DLSAIAKPWEIQSKVALSVAAEFWEQGDLERTVLEQQPIPMMDRNKAEELPKLQCGFIDF
VCSFVYKEFSRFHVEITPMLERLLNNRKEWNALKEIHEAKVAKLDEAKKAKEEAHANSDH
KQGNSVQPAAQSKTCVIS
>Gasterosteusaculeatus_PDE6B(ENSGACP_22195)
MVDAAAAEQFLDANPQFAKQYYDANFRPKVVSDLLDGNRKAAMDISAFHDLTAVEESEVL
FDLMRDIQDNLQMEKSVFNLMKHLSFMMRADRMSLFMYRQRNGVAELATRLFNVNKDSQF
DDCLVPPDSEIVYPLDMGIVGHVASTKKMVNIADVSESAHYSEFVDELTEYKTKSVLAIP
IMNGKDMVAVMMALNKLDGPRFTAKDEETLNKYLNFGNLILRVFHLSYLHNCETRKGQVL
LWSASKVFEELTDIERQFHKALYTVRAFLNCDRYSVGLLDMTKTKEFFDLWPVLMGEVPP
YDGPKTPDGREIIFYKLIDYILHGKEDIKVIPNPPADHWVLVSGLPTYVAETGLICNIMN
AGQDDFFKFQKIPLDDSGWTIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDEMDETLME
SLTQFLGWSVLNTDTYDKMNKLENRKDIFQDMVMYHVKCRKDEIQHVLNTRERWGKEPDE
CEEEALQEILSEVLPDSKKCELFEFHFYDFHHTELELVKCGIKMYYELKVVDKFHIPRET
LVRFIYSLSKGYRRITYHNWRHGFNVGQTMFTLLMTGDLKRYFTDLECMAMVTAGLCHDI
DHRGTNNLYQMKSGNPLAKLHGSSILERHHLEFGKTLLRDEALNIYQNLNRRQHDTVIHL
MDIAIIATDLALYFKKRTMFQKIVDQSKTYENWNEWTKYMMLETTRKEIVMAMMMTACDL
SAIAKPWEIQSKVALSVAAEFWEQGDLERTVLEQVPIPMMDRTKADELPKMQCGFIDFVC
AFVYKEFSRFHVEITPMLDRLMNNRKEWNALKEVHEAKMAAIEEAKKAKEEVAAGARQGR
YMFPNPPPGAAPRSSSCSTP
>Oryzias latipes_PDE6B(ENSORLP_12384)
MGVGKEDVEKFLLENPAFAKTYFAKKLSPSSISKVSGLPEKQIDFSQFQELSQIEESRLM
YDVIKDMQENVNMEKVVFKILKRISSLIHADRCSLFMYRQRNGIGELATRLFNVSMDSVL
EDCVVQPDSEIVYPLDLGIVGNVALTKKNVNVKNVKESQHFSSFVDELTDYETRNVLAAP
ILNGKDMVAVIMALNKTTGPHFTAEDEDLFLKYLKIASLNLKIFHLSYLHNCETRKGQLL
LWSANKVFEELTDIERQFHKALYTVRAYLNCDRYSVGLLDMTKEKEFFDIWPVLMGEQAP
YAGPVTPDGREVIFYKVIDYILHGKEDIKVIPNPTPDHWALQSGLPTYVAESGFICNIMN
AGADETFKFQTEALDDSGWTIKNVLSLPIVNKKEEIVGVATFYNRKDGKPFDDHDEQLME
ALTQFLGWSALNTDTYDKMNKLENRKDIAQDMVLYHVKCRNDEIQNVLNTREVYGCEPAE
CEEEDLLDILKKELPPLIKKFEIYEFRFSDFNCTELDLVKCGIQMYYEVGVVKKFQIPQE
VLVRFMYSVSKGYRKITYHNWRHGFNVGQTMFTLLTTGALKRYYTDLEVMAMITAGFLHD
IDHRGTNNLYQVKSGNPLAKLHGSSILERHHLEFGKFLLSDESLNIYQNLNRRQVDHVIH
LTDIAIIATDLALYFKKRTMFQKIVDLSKTYEEEKKWVDFMSLETTRKEIVMAMMMTACD
LSAITKPWEVQSKVALSVAAEFWEQGDLERTVLEQQPIPMMDRNKAAELPKLQCGFIDFV
CTFVYKEFSRFHPQIQPMLDGILNNRKEWNARKEEYEAKLKAIEEEMAAKEAAKAAKAAQ
NNSSGGGSKTCSVC
>Homo sapiens_PDE6A(ENSP_255266)
MGEVTAEEVEKFLDSNIGFAKQYYNLHYRAKLISDLLGAKEAAVDFSNYHSPSSMEESEI
IFDLLRDFQENLQTEKCIFNVMKKLCFLLQADRMSLFMYRTRNGIAELATRLFNVHKDAV
LEDCLVMPDQEIVFPLDMGIVGHVAHSKKIANVPNTEEDEHFCDFVDILTEYKTKNILAS
PIMNGKDVVAIIMAVNKVDGSHFTKRDEEILLKYLNFANLIMKVYHLSYLHNCETRRGQI
LLWSGSKVFEELTDIERQFHKALYTVRAFLNCDRYSVGLLDMTKQKEFFDVWPVLMGEVP
PYSGPRTPDGREINFYKVIDYILHGKEDIKVIPNPPPDHWALVSGLPAYVAQNGLICNIM
NAPAEDFFAFQKEPLDESGWMIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDEMDETLM
ESLTQFLGWSVLNPDTYESMNKLENRKDIFQDIVKYHVKCDNEEIQKILKTREVYGKEPW
ECEEEELAEILQAELPDADKYEINKFHFSDLPLTELELVKCGIQMYYELKVVDKFHIPQE
ALVRFMYSLSKGYRKITYHNWRHGFNVGQTMFSLLVTGKLKRYFTDLEALAMVTAAFCHD
IDHRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKTLLRDESLNIFQNLNRRQHEHAIH
MMDIAIIATDLALYFKKRTMFQKIVDQSKTYESEQEWTQYMMLEQTRKEIVMAMMMTACD
LSAITKPWEVQSQVALLVAAEFWEQGDLERTVLQQNPIPMMDRNKADELPKLQVGFIDFV
CTFVYKEFSRFHEEITPMLDGITNNRKEWKALADEYDAKMKVQEEKKQKQQSAKSAAAGN
QPGGNPSPGGATTSKSCCIQ
>Macaca mulatta_PDE6A(ENSMMUP_6320)
MGEVTAEEVEKFLDSNIGFAKQYYNLHYRAKVISDLLGAKEAAVDFSNYHSPSSVEESEI
IFDLLRDFQENLQTEKCIFNVMKKLCFLLQADRMSLFMYRTRNGIAELATRLFNVHKDAV
LEDCLVMPDQEIVFPLDMGVVGHVAHSKKIANVPNTEEDEHFCDFVDILTEYKTKNILAS
PIMNGKDVVAIIMAVNKVDGSHFTKRDEEILLKYLNFANLIMKVYHLSYLHNCETRRGQI
LLWSGSKVFEELTDIERQFHKALYTVRAFLNCDRYSVGLLDMTKQKEFFDVWPVLMGEVP
PYSGPRTPDGREINFYKVIDYILHGKEDIKVIPNPPPDHWALVSGLPTYVAQNGLICNIM
NAPAEDFFAFQKEPLDESGWMIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDEMDETLM
ESLAQFLGWSVLNPDTYESMNKLENRKDIFQDIVKYHVKCDNEEIQKILKTREVYGKEPW
ECEEEELAEILQAELPDAEKYEINKFHFSDLPLTELELVKCGIQMYYELKVVDKFHIPQE
ALVRFMYSLSKGYRKITYHNWRHGFNVGQTMFSLLVTGKLKRYFTDLEALAMVTAAFCHD
IDHRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKTLLRDESLNIFQNLNRRQHEHAIH
MMDIAIIATDLALYFKKRTMFQKIVDQSKTYESEQEWTQYMMLEQTRKEIVMAMMMTACD
LSAITKPWEVQSQVALLVAAEFWEQGDLERTVLQQNPIPMMDRNKADELPKLQVGFIDFV
CTFVYKEFSRFHKEITPMLDGITNNRKEWKALADEYDAKMKVQEEEKQKQQSAKPAAAGN
QLGGNPSPGGATTSKSCCIQ
>Mus musculus_PDE6A(ENSMUSP_25468)
MGEVTAEEVEKFLDSNIGFAKQYYNFHYRGKVISDLLGAKEAAVDFSNYHDVNSVEESEI
IFDLLRDVQENLQAEKCTFNVMKKLCFLLRADRMSLFMYRTRNGIAELATRLFNVHKDAV
LEDCLVMPDSEIVFPLDMGVVGHVAHSKKIANVPNTEEDEHFCDFVDNLTEYQTKNILAS
PIMNGKDVVAIIMAVNKIDEPHFTKRDEEILLKYLNFVNLIMKVFHLSYLHNCETRRGQI
LLWSGSKVFEELTDIERQFHKALYTVRAFLNCDRYSVGLLDMTKQKEFFDVWPVLMGEAP
AYSGPRTPDGREINFYKVIDYILHGKEDIKVIPNPPADHWALVSGLPTYVAQNGLICNIM
NAPAEDFFEFQKEPLDESGWMIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDDMDETLM
ESLTQFLGWSVLNPDTYESMNKLENRKDIFQDIVKYHVKCDNEEIQKILKTREVYGKEPW
ECEEEELAEILQGELPDAESYEINKFHFSDLPLTELELVKCGIQMYYELRVVDKFHIPQE
ALVRFMYSLSKGYRRITYHNWRHGFNVGQTMFSLLVTGKLKRYFTDLEALAMVTAAFCHD
IDHRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKTLLRDESLNIFQNLNRRQHEHAIH
MMDIAIIATDLALYFKKRTMFQKIVDQSKTYESTQEWTQYMMLEQTRKEIVMAMMMTACD
LSAITKPWEVQSKVALLVAAEFWEQGDLERTVLQQNPIPMMDRNKADELPKLQVGFIDFV
CTFVYKEFSRFHEEITPMLDGITNNRKEWKALADEYEAKMKALEEEKQKQQAAKQAASGN
QPGGNPTPGGAPASKSCCIQ
>Felis catus_PDE6A(ENSFCAP_3345)
MGEVTAEEVEKFLDSNVSFAKQYYNLRYRAKVISDMLGAKEAAVDFSNYHSLNSVEESEI
IFDLLRDFQENLQTEKCIFNVMKKLCFLLQADRMSLFMYRVRNGIGELATRLFNVHKDAV
LDECLVVPDSEIVFPLDMGVVGHVAHSKKLANVLNTEEDEHFCDFVDILTEYQTKNILAS
PIMNGKDVVAVLMAVNKLNEPHFTKRDEEILLKYLNFANLIMKVYHLSYLHNCETRRGQI
LLWSGSKVFEELTDIERQFHKALYTVRAFLNCDRYSVGLLDMTKQKEFFDVWPVLMGEAP
PYSGPRTPDGREINFYKVIDYILHGKEDIKVIPNPPPDHWALVSGLPTYVAQNGLICNIM
NAPAEDFFEFQKEPLDESGWMIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDEMDETLM
ESLAQFLGWSVLNPDTYESMNKLENRKDIFQDMVKYHVRCDNEEIQTILKTREVYGKEPW
ECEEEELAEILQGELPDAEKYEINKFHFSDLPLTELELVKCGIQMYYELKVVDKFHIPQE
ALVRFMYSLSKGYRRITYHNWRHGFNGQTMFSLLVTGKLKRYFTDLEALAMVTAAFCHDI
DHRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKTLLRDESLNIFQNLNRRQHEHAIHM
MDIAIIATDLALYFKKRTMFQKIVDQSKTYETEQEWTQYMMLEQTRKEIVMAMMMTACDL
SAITKPWEVQSKVALLVAAEFWEQGDLERTVLQQNPIPMMDRNKADELPKLQVGFIDFVC
TFVYKEFSRFHEEITPMLDGITNNRKEWKALADEYDAKMKALEEEKQKQQAGVQAAAGNQ
PGGNPGSAGGAPASKSCCIQ
>Homo sapiens_PDE6C(ENSP_360502)
MGEINQVAVEKYLEENPQFAKEYFDRKLRVEVLGEIFKNSQVPVQSSMSFSELTQVEESA
LCLELLWTVQEEGGTPEQGVHRALQRLAHLLQADRCSMFLCRSRNGIPEVASRLLDVTPT
SKFEDNLVGPDKEVVFPLDIGIVGWAAHTKKTHNVPDVKKNSHFSDFMDKQTGYVTKNLL
ATPIVVGKEVLAVIMAVNKVNASEFSKQDEEVFSKYLNFVSIILRLHHTSYMYNIESRRS
QILMWSANKVFEELTDVERQFHKALYTVRSYLNCERYSIGLLDMTKEKEFYDEWPIKLGE
VEPYKGPKTPDGREVNFYKIIDYILHGKEEIKVIPTPPADHWTLISGLPTYVAENGFICN
MMNAPADEYFTFQKGPVDETGWVIKNVLSLPIVNKKEDIVGVATFYNRKDGKPFDEHDEY
ITETLTQFLGWSLLNTDTYDKMNKLENRKDIAQEMLMNQTKATPEEIKSILKFQEKLNVD
VIDDCEEKQLVAILKEDLPDPRSAELYEFRFSDFPLTEHGLIKCGIRLFFEINVVEKFKV
PVEVLTRWMYTVRKGYRAVTYHNWRHGFNVGQTMFTLLMTGRLKKYYTDLEAFAMLAAAF
CHDIDHRGTNNLYQMKSTSPLARLHGSSILERHHLEYSKTLLQDESLNIFQNLNKRQFET
VIHLFEVAIIATDLALYFKKRTMFQKIVDACEQMQTEEEAIKYVTVDPTKKEIIMAMMMT
ACDLSAITKPWEVQSQVALMVANEFWEQGDLERTVLQQQPIPMMDRNKRDELPKLQVGFI
DFVCTFVYKEFSRFHKEITPMLSGLQNNRVEWKSLADEYDAKMKVIEEEAKKQEGGAEKA
AEDSGGGDDKKSKTCLML
>Macaca mulatta_PDE6C(ENSMMUP_19304)
MGEINQDAVEKYLEENPQFAKEYFDRKLRVEVLGEIFKNSQVPVQSSMSFSELTQVEESA
LCLELLWTVQEEGGTPEQGVHRALQRLAHLLQADRCSMFLCRSRNGIPEVASRLLDVTPT
SNFDDNLVGPDKEVVFPLDIGIVGWAAHTKKTHNVPDVKKNSHFSDFMDKQTGYVTKNLL
ATPIVMGKEVLAVIMAVNKVNASEFSKQDEEVFSKYLNFVSVILKLHHTSYMYNIESRRS
QILMWSANKVFEELTDVERQFHKALYTVRTYLNCERYSIGLLDMTKEKEFYDEWPIKLGE
VEPYKGPKTPDGREINFYKIIDYILHGKEEIKVIPTPPADHWTLISGLPTYVAENGFICN
MMNAPADEYFTFQKGPVDETGWVIKNVLSLPIVNKKEDIVGVATFYNRKDGKPFDEHDEY
ITETLTQFLGWSLLNTDTYDKMNKLENRKDIAQEMLMNQTKATPEEIKSILKFQEKLNVD
VIDDCEEKQLVAILKEDLPDPRSAELYEFRFSDFPITEHGLIQCGIRLFFEINVVEKFKV
PVEVLTRWMYTVRKGYRAVTYHNWRHGFNVGQTMFTLLMTGRLKKYYTDLEAFAMLAAAF
CHDIDHRGTNNLYQMKSTSPLARLHGSSILERHHLEYSKTLLQDESLNIFQNLNKRQFET
VIHLFEVAIIATDLALYFKKRTMFQKIVDACEQMQTEEEAIKYVTVDPTKKEIIMAMMMT
ACDLSAITKPWEVQSQVALMVANEFWEQGDLERTVLQQQPIPMMDRNKRDELPKLQVGFI
DFVCTFVYKEFSRFHKEITPMLSGLQNNRVEWKSLADEYDAKMKVIEEEAKKQEEGAEKA
AEDSGGGDDKKSKTCLML
>Mus musculus_PDE6C(ENSMUSP_25956)
MGEISQEAVERYLEKNPCFAKEYFDKKLRVEALGVIFKNSHAGVQTGLSLPEMTQVEESA
VCLELLQCMQDEAGSAEQMAHRALQRLAQLLQADCCSMFSCRARNGIPEVASRLLNVTPT
SKFEDNLVAPDREVVFPLDIGIVGWVAHVKKALNVSDVKKNSHFSDFMDKQTGYVTRNLL
AVPIVAGKEVLAVVMAVNKISAPEFSKQDEEVFSKYLSFVAVALRLQHTSYLYSVESRRS
QILMWSANKVFEELTDVERQFHKALYTIRTYLNCDRYSIGLLDMTKEKEFYDEWPIKLGE
VEPYKGPKTPDGREIIFYKIIDYILHGKEEINVIPSPPADHWTLVSGLPTYVAENGFICN
MLNAPADEYFTFQKGPVDETGWVIKNVLSLPIVNKKEDIVGVATFYNRKDGKPFDEHDEH
ITETLTQFLGWSLLNTDTYERVNKLESRKDIAQEMVMNLTKATPDEISSILKFKEKLNVE
VIEECEERQLLAILKEDLPDPRTADLYEFCFSDFPITEHELVKCGLRLFLEINVVEKFKV
PVEVLTRWMYTVRKGYRPVTYHNWRHGFNVGQTMFTLLMTGRLKKYYTDLEAFAMLAAAF
CHDIDHRGTNNLYQMKSTSPLARLHGTSILERHHLEYSKTLLQDESLNIFQNLNKRQFET
VIHLFEVAIIATDLALYFKKRTMFQKIVDTCEQMQSEEETIKYVTSDPTKKEVIMAMMMT
ACDLSAITKPWEVQSQVALLVANEFWEQGDLERTVLQQQPIPMMDRSKKDELPKLQVGFI
DFVCTFVYKEFSRFHGEITPMLNGLQNNRVEWKSLAEEYEAKVKVTEEEAGKQEEEASDG
KAATDLGGSAEDKKSKTCLML
>Felis catus_PDE6C(ENSFCAP_21685)
MGEISQEAVEKYLEDNPQFAKEYFAKRLAEAPGPCGALSPADEWALCAELLRAVQEEARG
AEPAVHGALQKLAQLLQADRCSLFACRARNGTPEVASRLFDVTPTSRFEDNLVGPDREVV
FPLEIGIVGWVAHTKKAVNVPDVHKNSHFSDFMDKQTGYVTKNLLATPIMIGKEVLAVVM
AVNKVNASEFSKEDEEVFSKYLSFVSVILKLHHTQYLYSVESRRSQILMWSANKVFEELT
DVERQFHKALYTIRTYLNCERYSIGLLDMTKEKEFYDEWPIKLGEVEPYKGPKTPDGREV
IFYKIIDYILHGKEEIKVIPTPPADHWTLVSGLPTYVAENGFICNMLNAPADEYFTFQKG
PVDETGWVIKNVLSLPIVNKKEDIVGVATFYNRKDGKPFDEYDEHITETLTQFLGWSLLN
TDTYDKMNKLENRKDIAQEMLMSQTKATPDEVKSILKIKEKLNIDVIEDCEEKQLVTILK
EDLPDPQTVDLYEFRFSDFPITEHELIRCGLRLFFEINVVEKFKVPVEVLTRWMYTVRKG
YRSITYHNWRHGFNVGQTMFTLLMTGRLKKYYTDLEAFAMLAAAFCHDIDHRGTNNLYQM
KSTSPLAKLHGSSILERHHLEYSKTLLQDESLNIFQNLNKRQFETVIHLFEVAIIATDLA
LYFKKRTMFQKIVDACEKMETEEEAVKYVTIDPTKKEVIMAMMMTACDLSAITKPWEVQS
QVALLVANEFWEQGDLERTVLQQQPIPMMDRNKKDELPKLQVGFIDFVCTFVYKEFSRFH
KEITPMLTGLQNNRVEWKSLADEYDAKMKVIEEETKKQEEGNMAAKEDSGGGSDDKKSKT
CLML
>Gallus gallus_PDE6C(ENSGALP_10688)
MGEVNKDAVEKYLENNPQFAKEYFDRKMRAEVLGSIFQVSPGDVKEGVSFKDMSRLEECN
ILFELLTEIQDEAGSMEKIVHKTLQRLSQLLAADRCSMFICRSRNGIPEVATRLLNVTPT
SKFEENLVNPDKETVFPLDIGIAGWVAHTKKFFNIPDVKKNNHFSDYLDKKTGYTTVNMM
AIPITQGKEVLAVVMALNKLNASEFSKEDEEVFKKYLNFISLVLRNHHTSYLYNIESRRS
QMLLWSANKVFEELTDIERQFHKALYTIRMYLNCERYSVGLLDMTKEKEFYDEWPIRLGE
AEPYKGPKTPDGREVNFYKIIDYILHGKEEIKVIPTPPADHWCLISGLPTYVAENGFICN
MMNAPADEYFTFQKGPVDETGWVIKNVLSLPIVNKKEEIVGVATFYNRKDGKPFDEYDEQ
IIETLTQFLGWSVLNTDTYDKMNKLENRKDIAQEMLMYQTKATPTEVESILKYKEKLNVK
SIEECDEKDLIRILKEELPDPKDLELYEFRFSDFPVTEHGLITCGIRLFFEINVVEKFKV
PAEVLTRWMYTVRKGYRDITYHNWRHGFNVGQTMFTLLMTGRIKKYYTDLEAFAMVAAAF
CHDIDHRGTNNLYQMKSAAPLAKLHGSSILERHHLEYSKTLLQDESLNIFQNLNKRQFET
VLHLFEVAIIATDLALYFKKRTMFQKIVDAIEKMETEEEAIKYISIDPTKKEVIMAMMMT
GCDLSAITKPWEVQSKVALMVANEFWEQGDLERTVLQQQPIPMMDRNKGDELPKLQVGFI
DFVCTFVYKEFSRFHKEITPMFDGLQNNRVEWKTRADEYEEKMKVIEEQKKKEEEAAAKK
AENAAGGGGGGEDGKSKTCIVL
>Anolis carolinensis_PDE6C(ENSACAP_7118)
MGGISKDDVEKYLENNPQFAKEYYDRKLRLEAVGSVFKVNPGDVKDGISFKEMTKLEESQ
MLFELLLQIQEQDMEQDMEKIVHKVLQRLCQLLAADRCSMFVGRSRNGIPEMAARLLDVT
PTSKYEDNLIPPEKEIVFTLDIGIVGWVAHTKKLFNIPDVKKNNHFSDSVDKQTGYTTIN
MLATPIIHNKEVLAVIMVLNKKTEPEFSKEDEEVFKKYINFITIAIKHNHISNMYNLEMR
KSQMLLWCGNKVFEELTDIERQFHKALYTIRIYLNCERYSVGLLDMTKEKEFYDEWPIKL
GEAEPYKGPKTPDGREVNFYKIIDYILHGKEEIKVIPSPPADHWCLASGLPTYVAENGFI
CNMMNAPSDEYFNFQKEAFDETGWIVKNVLSLPIVNKKEEIVGVATFYNRKDGRPFDEYD
EQITEMLTQFLGWSVLNTDTYDKMNKLENRKDIAQEMLMYQTKATPEEIQSILKWKEKLK
VDSIEDCDEKQLLKILKEELPDPSNVELYEFRFSDFPVTEHELIKCGIRLFFEINVVEKF
KVPAEVLTRWMYTVRKGYRDITYHNWRHGFNVGQTMFTLLMTGKIKKYYTDLEAFAMVSA
AFCHDIDHRGTNNLYQMKSAAPLARLHGSSILERHHLEYSKTLLQDESLNIFQNLNKRQF
ETVLHLFEVAIIATDLALYFKKRTMFQKIVDAIEKMEKEEEAIRYISTDPTKKEVIMAMM
MTGCDLSAITKPWEVQSKVAIMVANEFWEQGDLERNVLQQQPIPMMDRNKSEELPKLQVG
FIDFVCTFVYKEFSRFHKEITPMFDGLNNNRVEWKSRADIYEEKMKAIEEEKKKQEEAEA
KKGGAHYWGGGLPTGSPSTSFIIIR
>Xenopus tropicalis_PDE6C(ENSXETP_8075)
EMKKEDIEKYLENNPQFAKEYFDKKLRSETVGALFNSKELVLKDGVSFREMTKIEEADIL
LELIKEIQDDCNMEKTVHKVLQRMAYLLQADCCSMFGFRSRNGIPELATRLFNVTKSSKF
EDNLVAPESEIVFPLDIGIVGWVAHTKKSFNVPDVKKNTHFSDFADKQTGYTTKNLLAAP
ILQGKEVLAVMMAVNKQNAAEFSKEDEEVFHKYLNFISVVLKYNHINYLHNIETRKSQVL
LWTANKVFEELTDIERQFHKALYTVRVYLNCERYSVGLLDMTKEKEFYEEWPIKLGEVPP
YKGPKTPDGREVIFYKIIDYILHGKEEIKVIPTPPEDHWSLVSGLPTYVAENGFICNMMN
APADEFFKFQKEAVDETGWTIKNVLSLPIVNKKEEIVGVATFYNRKDAKPFDEYDEQITE
ALTQILGWSVLNTDTYDKMNKLENRKDIAQEMLMYQLKCTPKELQSILKTKEKLNKEVEE
CEETELLKILKEELPDPITAELYEFHFSDLPVSEHDLIKSGIRLFFEINAVDKFKVPVEV
LTKWMYTVRKGYRDITYHNWRHGFNVGQTMFTLLMTGKLKKYYSDLEAFAMVAAAFCHDI
DHRGTNNLYQMKSQAPLAKLHGSSILERHHLEFSKTLLQDESINIFQTLNKRQFENVIHL
FEVAIIATDLALYFKKRTMFQKIVDTTEQMQSEDERIKYIICDPTKKEIIMAMMMTGCDL
SAITKPWEVQSKVALMVANEFWEQGDLERTVLQQQPIPMMDRNKSDELPKLQVGFIDFVC
TFVYKEFSRFHKEILPMYDGLQNNRVQWKSQADVYEEKMKILDEQKKKEEPNGGNPGQGG
ELVKSKTCTLL
>Danio rerio_PDE6C(ENSDARP_97279)
MADKDSVEKYLENNPQFAKEYFDKKVRCEVIAAAFEEKLDIKDPASFKDVTQVQEAAILF
DMIQDMHSQPVMEKAMHKVLQRICLLVNADRCSYFISRARNGIPELATCLFDVTPTSKYE
ANLVNPQSEIVFPTDTGIVGQIVTTKKPANVPDVKQNPRFSDFVDKQTGYTTKNMMAAPL
MQGKDPLGVVMAINKVGANEFSKEDEDVFSKYIIFATVIALQHYTNYMYNVESRRSQVLL
WSASKVFEELTDIERQFHKALYTVRTYLQCERYSCGLLDMTKEKEFYDEWPIKLGDVEPY
KGPKTPDGREIIFYKIIDYLLEGKEEIKVIPNPPADHWALVSGLPSYVAENGFICNMMNV
AADEYFTFQKEAVDETGFVIKNVLSLPIVNKKEEIVGVATFFNRKDGKPFEEQDEQITEA
LTQFLGWSVLNCDTYDKLNRMEWRKEIAEEMVMYQTKATPAEVQQILNTKEKFDQNPEDC
DQKEMYKLLRANIPEAKDVDLLEFSFSDFPLTETDLIKCGIRCFFELGVVEKFKVPAEVL
TRWMYTVRKGYRDITYHNWRHGFNVGQTMFCLLQTGKLRRYYTDLDAFAMVAAAFCHDID
HRGTNNLYQTKSASPLAKLHGSSILERHHLQYSKNLMAEENVNIFQSLQKRQFETVQHLH
DVCIIATDLALYFKKRTMFQKIVDATEPMTKEEEMVAHVANNPIRKEIIMAMMMTGCDLS
AITKPWEVQSKVALMVAAEFWEQGDLERTVLDQQPIPMMDRNKSDELPKMQCGFIDFVCS
FVYKEFSRFHKEITPMFDGLNNNRVHWKELADIYQAKIDAIANEKKRLEEEQAKKGGEEG
GEGGKSKTCTIF
>Takifugu rubripes_PDE6C(ENSTRUP_28323)
FNMADKDTVEKFLDNNPEFAKVYYEKKVKADVITAAFNNQVQVKDPASYKDLSTIQEAEF
IFELIKEIQSSNPLEKILHKILQRIALLIQADRCSYFGCRARNGTPELSTILFDVTHNSP
LEKNIVNPNVEIVFPTDMGVVGWTAHSKKPQNIPDVKKDSHFSDFVDKQTKYTTKCVITA
PVMSGKEPIGVIMALNKQGAEDFSKSDQELFNKYVNFAAVVVMQAHTSYMWDVESRKSQV
LLWAASKVFEELTDIERQFHKALYTVRTYIKCERYSVGLLDMTKDKEFFDEWAIKLGDQE
PYKGPKTPDGREISFYKIIDYLLEDKEEIKVIPGPPADHWALVSGLPSYVAENGMICNMM
NAAADDYFTFQKEAVDESGWKIKNVLALPIVNKKEEIVGVATFFNRKDGKPFDENDEQII
ESLTQFLGWATLNSDTYDKLNRTEWRKEVAQEMLMYQTKASLSDVQTILNTQEKFGSDPE
DCDQKEMYKLLKSNIPDAKTVDLHEFHFSDFPLSEFELIKCGIRCFFELGVVEKFKVQAE
TLTRWMYTVRKGYRDITYHNWRHGFNVGQTMFTLLLTGKLKKYYSDLDAFAMVAAGFCHD
IDHRGTNNLYQTKSLSPLAKLHSSSVMERHHLEYSKTLMEDENLNIFQNLQKRQFETVQH
LFEVCIIATDLALYFKKRTMFQKLVESMQAMPEEKERISYVSNNPTRKEIIMAMMMTACD
LSAITKPWEVQSKVALMVAAEFWEQGDLERTVLEQQPIPMMDRNHADELPKMQCGFIDFV
CSFVYKEFAHFHSEIQPMFDGLNNNRCEWKALADVHEAKIKAIEDGKKKPEEPDQSKPSA
TDVTSLITVVNIPSLLFL
>Oryzias latipes_PDE6C(ENSORLP_6480)
VKMADKDSVEKYLDNNPQVAKDYFDKKIRAEALTAAFSQTVDVKDTASFKDVNAIQESAI
IFELVKELQKVENMEKSLHKVLQRVALILQADRVGFFQCRSRNGIPELSSSLFDVTPTSK
FESNLVNPQAEIVFPLDMGIVGHTANSKKPQNVPDVTKNPKFSDFVDKQTGYKTKCMLTF
PLMAEKECLGVVMMLNKIGADAFTAEDEKLFHKYMTFAQVITLQHYTTYMFNVESRRSQV
LLWSASKVFEELTDIERQFHKALYTVRTYLQCERYSVGLLDMTKEKEFYDEWPVKLGDVE
PYKGPKTPDGREIIFYKIIDYLLEAKEEIKVIPGPPADHWALISGLPTYVAENGFICNMM
NVAADDYFTFQKEAVDETGFVIKNVLSLPIVNKKEEIVGIATFFNRKDGKPFDEHDEQIT
EALTQFLGWSVLNCDTYDRLNRMEYRKDIAQEMLMYQSKCTPAELQSILNTKEKFDAEPE
DCDQKEMYKLLKSNIPPADNVDGESLYSFAFSDFPVSEFGLIKAGIRMFFELGVVEKFKV
PAETLVRWMYTVRKGYRAITYHNWRHGFNVGHTMFCLLQTGKLRKYYSDLDAFAMVAAAF
CHDIDHRGTNNLYQTKSASPLAKLHGSSIMERHHLEYSKTLMGEECLNIFCNLQKRQFEN
VQHLFDVCIIATDLALYFKKRTMFQNIVNATEPMTDEKEATAYISNNSIRKEIVMAMMMT
GCDLSAITKPWEVQSKVALMVAAEFWEQGDLERSVLDQQPIPMMDRNCAEQLPKMQCGFI
DFVCSFVYKEFSRFHKEIQPMFDGLNNNRAHWNELAEVYNAKMKAIEDEKKRLEEEEAKK
GKEQKHGAGGGEVGKSKTCTIS
>Homo sapiens_PDE11A(ENSP_286063)
MAASRLDFGEVETFLDRHPELFEDYLMRKGKQEMVEKWLQRHSQGQGALGPRPSLAGTSS
LAHSTCRGGSSVGGGTGPNGSAHSQPLPGGGDCGGVPLSPSWAGGSRGDGNLQRRASQKE
LRKSFARSKAIHVNRTYDEQVTSRAQEPLSSVRRRALLRKASSLPPTTAHILSALLESRV
NLPRYPPTAIDYKCHLKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSL
FLVEGAAAGKKTLVSKFFDVHAGTPLLPCSSTENSNEVQVPWGKGIIGYVGEHGETVNIP
DAYQDRRFNDEIDKLTGYKTKSLLCMPIRSSDGEIIGVAQAINKIPEGAPFTEDDEKVMQ
MYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKC
ERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESMEKSSYSDWLINNSIAELVA
STGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFD
DADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANI
PLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRM
VLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSG
SALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLY
FERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFE
QGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVAT
NRSKWEELHQKRLLASTASSSPASVMVAKEDRN
>Macaca mulatta_PDE11A(ENSMMUP_2693)
MAASRLDFGEVETFLDRHPELFEDYLMRKGKQEMVEKWLQRHSQGQGALGPRPSLAGTSS
LAHSTCKGGSSIGGGIGPNGSAHSQPLPGGGDCGGVPLSPSWASGSRGDGNLQRRASQKE
LRKSFARSKAIHVNRTYDEQATSRAQEPLSSVRRRALLRKASSLPPTTAHILSALLESRV
NLPQYPPTAIDYKCHLKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSL
FLVERAAAGKKSLVSKFFDVHAGTPLLPCSSTENSNEVQVPWGKGIIGYVGEHGETVNIP
DAYQDRRFNDEIDKLTGYKTKSLLCMPIRSSDGEIIGVAQAINKIPEGAPFTEDDEKVMQ
MYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKC
ERCSVLLLEDIESPVVKFTKSFELLSPKCSADAENSFKESMEKSSYSDWLINNSIAELVA
STGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFD
DADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANI
PLVSELAINDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRM
VLYHNWRHAFNVCQLMFAMLTTAGFQEILTEMEILAVIVGCLCHDLDHRGTNNAFQAKSG
SALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLY
FERRTEFFELVSKGEYDWNIKNHRDVFRSMLMTACDLGAVTKPWEISRQASELVTSEFFE
QGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVAA
NRSKWEELHQKRLLASTASSSPASVMVATEDRN
>Mus musculus_PDE11A(ENSMUSP_97572)
MAASRLDFGEVETFLDRHPELFEDYLMRKGKQELVDKWLQRHTSGQGASSLRPALAGASS
LAQSNAKGSPGIGGGAGPQGSAHSHPTPGGGESAGVPLSPSWASGSRGDGSLQRRASQKE
LRKSFARSKAIHVNRTYDEQVTSRAQEPLSSVRRRALLRKASSLPPTTAHILSALLESRV
NLPQYPPTAIDYKCHLKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSL
FLVEGAAAGKKTLVSKFFDVHAGTPLLPCSSTENSNEVQVPWGKGIIGYVGEHGETVNIP
DAYQDRRFNDEIDKLTGYKTKSLLCMPIRNSDGEIIGVAQAINKVPEGAPFTEDDEKVMQ
MYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKC
ERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESVEKSSYSDWLINNSIAELVA
STGLPVNVSDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFD
DADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANI
PLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRM
VLYHNWRHAFNVCQLMFAMLTTAGFQEILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSD
SALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLY
FERRTEFFELVRKGDYDWSITSHRDVFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFE
QGDRERSELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNAKLKPMLDSVAA
NRRKWEELHQKRLQVSAASPDPASPMVAGEDRL
>Felis catus_PDE11A(ENSFCAP_17362)
MTASHLDFGEVETFLDRHPELFEDYLMRKGKQEMVEKWLQRHSESQGAVGPRPAVASTNS
LAHSGGRRSGSVGGGPGPNSSANSQPTLGGGDCGGVPLSPSWASGSGGDGSLQRRASQKE
LRKSFARSKAIHVNRTYDEQVTSRAQEPLSSVRRRALLRKASSLPPTTAHILSALLESRV
NLPQYPPTAMDYKCHLKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSL
FLVEGAAAGKKSLVSKFFDVHAGTPLLPCSSTENSNEVQVPWGKGIIGYVGEHGETVNIP
DAYQDRRFNDEIDKLTGYKTKSLLCMPIRSSDGEIIGVAQAINKIPEGAPFTEDDEKVMQ
MYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKC
ERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESMEKSSYSDWLINNSVAELVA
STGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKAFD
DADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDNQVLSYHATCSKAEVDKFKAA
NIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNY
RMVLYHNWRHAFNVCQLMFAMLTTAGFQEILTEVEILAVIVGCLCHDLDHRGTNNAFQAK
SGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLT
LYFERRTEFFELVSKGEYDWNIKNHRDVFRSMLMTACDLGAVTKPWEISRQVAELVTSEF
FEQGDRERSELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSV
AANRSKWEELHQKRLLVPAASPSSASVVAAGEDRN
>Gallus gallus_PDE11A(ENSGALP_14983)
MAADGGLDVAAVESFLDRHPELVERWLKRRNSLPKAPAGGPSEERRVGGGWGGAGGPGAG
GLQRRASQKELRKSFARSKAIHVNLTYDEHVHARAQEPLSSVRRRALLRKASSLPPTTAH
ILSALLESRVSLPQYPPPALDYKRYLKEHNERQFFLELVKDISNDLDLTSLSYKILIFVC
LMVDADRGSLFLVEGAAAGKKSLVSKFFDVHAGTPLLPCGSTENSSEVQVPWGKGIIGYV
AEHGETVNIPDAYQDRRFNDEIDKLTGYKTNHFCVCPKNSDGEIIGVAQAINKTPGGAPF
LMTMKKKVMQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVNDLFEEQTDLEKIVKKI
MHRAQTLLKCERCSVLLLEDIESPVVKFTKSFELLSPKCSADTENSFKEGVEKSPSYSDW
LINNSIAELVASTGLPVNISDAYQDPRFDAEADQIFGFHIRSVLCVPIWNSSHQIIGVAQ
VLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSK
AEVDKFKAANIPLVSELGIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCR
WLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQEILTEIEILALIVGCLCHDLDHR
GTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKDYSDLMQLLK
QSILATDLTLYFERRTEFFELVGKGGYDWNVKNHREIFRSMLMTACDLGAVTKPWEISRQ
AAELVTSEFFEQGDRERSELKLIPSAIFDRNRKDELPRLQLEWIDSICMPLYECLVKLNV
KLKPMLDSVAKNRGKWEELHHQRLPSQAASSSSFPSTFTMSLKDIN
>Anolis carolinensis_PDE11A(ENSACAP_11888)
GSSGAVPLAWAEESGALHRRASQKELRRSFARSKAIPVNRTYEEPGRARAQEPSLRSARR
RALLRKASSLPPTTAHILSALLESRVNPPACPPTALDYKRQLKQHNERQFFLELVKDISN
ELDLRALSYKILIFVCLMVDADRGSLFLVEAGAAGKKSLVSKVFDVHAGTPLLPCCCCGG
AAEDANEAQVPWGKGIIGYVAEHGQTVNLPDAYQDRRFNDEIDKLTGYKTKSLLCMPIRS
SDGEIIGVAQAINKTPGGAPFTDDDEKVMEMYLPFCGIAISNAQLFAASRKEYDRSRALL
EVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFTKSFELMSPKCS
ADTENSFKDSLEKTSSSYSDWLVNNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFH
IRSVLCVPIWNSSHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVK
KSWAKQSVALDVLSYHATCSKAEVDKFKAANLPLVTELGIDDIHFDDFSLDMDAMITAAL
RMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQEI
LTEIEILALIVGCLCHDLDHRGTNNAFQAKIGSALAQLYGTSATLEHHHFNHAVMIIQSE
GHNIFANLSSKDYSDLMQLLKKSILATDLTLYFEKRAEFFELVNKGDYNWNIKSQREIFR
SMLMTACDLGAATKPWEISRQVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPRL
QLEWIDSICMPLYQVLVKVNGKLKPMLDSVVVNRRNWEELHQQRLLSKAAATEPTKSSSS
SSSSSQSAKCPKDIN
>Xenopus tropicalis_PDE11A(ENSXETP_18528)
MSEPALDFSKVERYLDNHPELFEDYLIRKGKHQMVERWMKRNQLAKTPSSSSADDKSKDC
WSNRGDGLQRRASQKELRKSFARSKAINVNRTYDEHVNSRAQEPLTSMRRRALLRKASSL
PPTTAHILSALLESRVNIPQYPSTAIDYIYYLKEHNERAFFLELVKDISNELNLTSLCYK
ILIFVCIMVDADRCSLFLVEGTANKKSLVSKFFDVHAGTTLLPSCSTENSNEVQVPWGKG
IIGYVAEHGETVNIPDAYQDRRFSDEIDKLTGYKTKSLLCMPIRSSDGEIIGVAQAINKT
PGGAPFIEDDEKVMQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVNDLFEEQTDLEK
VVKKIMHRAQNLLKCERCSVLLLEDIESPVVKFTKSFELLSPKCSADTENSFKDSVEKSS
YSDWLVNNSIAELVASTGLPVNISDAYQDPRFDVEADQFSGFHIRSVLCVPIWNSSHQII
EGVAQVLNRIDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYH
ATCSKAEVDKFKAANIPLVSELSIADIHFDDFCLDVDAMISAALRMFMELGMVQKFKIDY
ETLCRWLLTIRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQEVLSDTETLALIVGCLCH
DLDHRGTNNAFQAKSGSALSQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSQEYSDL
MQLLKQSILATDITLHFERRNEFFELVNKGDYNWNVKSHRVIFRSMLMTACDLGAATKPW
EISRQVAELVTSEFFEQGDRERLELKMTPSAIFDRNRKDELPRLQLEWIDNICFPLYESL
VKINGKLKPMLDSVTTNRGKWEELHRKQGNSSSTSYPTPASSPQPAIECLLKT
>Danio rerio_PDE11A(ENSDARP_87859)
MAGANMVFSDVETFLDEHPELLEDYLNRKGKASMVEKWMKSHPKTPEKAASACAKDSWAS
RGDGLQRRASQKELRKTFARSKAINANRTYDEHVNSRAQEPLTSMRRRALLRKASSLPPT
TAHILSALLESRVNIPQYPSTAVDYKYYLKEHNEREFFLELVKDISNDLDLTSLSYKILV
FVCIMVDADRCSLFLVEGPTNKKTLVSKFFDVHAGTTVLPSLSNSDEVQVPWGKGIIGYV
AEHGETVNIPDAYQDHRFSDEIDKLTGYKTKSLLCMPIHNSDGEVIGVAQAINKSPNGAL
FTQDDEKVLLAQCFMPFCGIAISNAQLFAASRKEYDRIKSTLHLCTKAGRLHNVFLEIWS
DFMHRAQTLLSCWCYLLQVVKFTKSFELLSPKCSADMENSFKDSMDKSSYSDWLINNSIA
ELVASTGLPVNISDAYQDPRFDAEADQFSGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDG
KPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKTEVDKFK
AANIPLVCELGIDKLSFDDFSLDVDAMVTAALRMFMELGMVQKFKIDYETLCRWLLTVRK
NYRMVLYHNWRHAFNVCQCMFSMLTTAGFQETLTEMETLALIVGCICHDLDHRGTNNAFQ
AKTGSALSLLYGTSATLEHHHFNHAVMILQSEGHNIFSNLSSHEYGELMQLLKQSILATD
LTLYFQNRNSFFELVNKGEYNWNVKEHREMCRSMLMTACDLGAVTKPWEISHKVAELVTS
EFFEQGDRERSELKLTPSTQTKTNRKTGKGRLFSKFKWICAPLYETFAKLNPKLQPMMDL
IKANRAKWEELHHRHQRISQEASIPASPDHAEVSSSCS
>Takifugu rubripes_PDE11Aa(ENSTRUP_44767)
MAVPKMVFSDVESFLDSHPELFEDYLNRKGSSSMVEKWLKNHQAGKSEAEPKEEKSSVCK
DSWASKCDGLQRRASQKELRKTFARSKAINVNRTYDEHVNSRAQEPLTSMRRRALLRKAS
SLPPTTAHILSALLESRVNIPQYPSTAVDFKYYLKEHNEREFFLELVKDISNDLDLTSLS
YKILVFVCIMVDADRCSLFLVEGTGNKKTLVSKFFDVHAGTTVLPSMNSGEVQVPWGKGI
IGYVAEHGETVNIPDAYQDRRFSDEIDKLTGYKTKSLLCMPIQNSDGEIIGVAQAINKSS
SGELFTEDDEKVLQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVNDLFEEQTDLEKI
VRKIMHRAQTLLKCERCSVQLLEDIESPVVKFTKSFELLSPKCSADAESSFKDSMEKSSY
SDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQFSDFHIRSVLCVPIWNSNHQIIG
VAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHAT
CSKTEVDKFKAANIPLVCELGIDKLSFDDFSLDVDAMITAALRMFIELGMVQKFKIDYET
LCRWLLTVRKNYRMVLYHNWRHAFNVCQCMFAMLTTQTAGFQETLTDVEILALIVGCVCH
DLDHRGTNNAFQAKTGSALSLLYGTSATLEHHHFNHAVMILQSEGHNIFCNLSSTEYSDL
MQLLKQSILATDLTLYFENRNSFFELVSIGEYNWNVKTHRDMCRSMMMTACDLGAVTKPW
DISRKVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPGLQLEWIDGICAPLYETL
VKLNPKLQPMVDMINANRVKWEELDKKRQHDHGASVPASPCSAAEGSETGGVPCCSNNTP
PTHVS
>Takifugu rubripes_PDE11Ab(ENSTRUP_38601)
FTMTTFDFSDVEAFLDCHPDLFEEYLVRKAKCDQVGRWLKEHQPSKVSAAEERRGAPRDQ
TWSTNPEALRRRSSHMELRRNFARSKATTAHRTYDEHVNLSEYEYESSMRRRALLRKASS
LPPTTAHILSALLESRVNVPQYASSAIDYKYRLKETNEREFFLELVKDISNDLDLTNLSY
KILINVCILVDADRCSLFLVEGPAHKRTLVSKFFDVHSGTTVRPSSSTLNSNEVQVPWGK
GIIGYVAEHGETVNIPNAYEDHRFSDEIDKLTGYKTQSILCLAICNSDGEVIGVVQAINK
NPMGTPFTEDDEKVLQMYLPFCGISISNAKLFSESRKEYERSRALLEVVNDLFEEQTDLE
KIVRKIMQRALTLLQCERCSVLLLEDIDSPVVKFSKTFELMSPLCTMDHDISFLGRISME
KLSCSDWLINNSIAELVASTGLPVNISDVCQDPRFDAEADQASGFHIRSVLCVPIWNRTH
QIIGVAQILNRLDRKTFNDADQRLFEAFVIFCGLGINNTMMYNQVKKTWAKQSVALDMLS
YHATCSKVEVDRLKAAKIPLSSELGIDEFHFNDFSLDNDAMITASLRMFLELGVVQKFKI
DYEVLCRWLLTVRKNYRTVAYHNWRHAFNVSQCMFIMITTASFQDLLSDAEILALMVGCL
CHDLDHRGTNNAFQAKTGSALALLYGTSATLEHHHFNHAVMILQSEGHNIFANLCSKEYS
NMMQLLKQAILSTDLTLHFERRTKFFESVLSGEFKWTDEGHREVFRSMLMTACDLGAVTR
PWKISKQVAELVTSEFFEQGDRERAELKLTPAPIFDRNRKDELPDLQLEWIDGICKPLYK
TLLKLNRKLQPMVDEMDANRNKWQDLCLSETRRASLTNQSADLSQNPESCENRE
>Homo sapiens_PDE10A(ENSP_438284)
MEDGPSNNASCFRRLTECFLSPSLTDEKVKAYLSLHPQVLDEFVSESVSAETVEKWLKRK
NNKSEDESAPKEVSRYQDTNMQGVVYELNSYIEQRLDTGGDNQLLLYELSSIIKIATKAD
GFALYFLGECNNSLCIFTPPGIKEGKPRLIPAGPITQGTTVSAYVAKSRKTLLVEDILGD
ERFPRGTGLESGTRIQSVLCLPIVTAIGDLIGILELYRHWGKEAFCLSHQEVATANLAWA
SVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALF
QVDHKNKELYSDLFDIGEEKEGKPVFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADP
RFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCAL
ALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLMQFTLPVRLCKEIELFHFDIG
PFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAI
LQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTV
SILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQS
HRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKD
EVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEETATWISSPSV
AQKAAASED
>Macaca mulatta_PDE10A(ENSMMUP_31087)
AAAAALLFGSDMEDGPSNNASCFRRLTECFLSPSLTDEKVKAYLSLHPQVLDEFVSESVS
AETVEKWLKRKNNKSEDESAPKEVSRYQDTNMQGVVYELNSYIEQRLDTGGDNQLLLYEL
SSIIKIATKADGFALYFLGECNNSLCIFTPPGIKEGKPRLIPAGPITQGTTISAYVAKSR
KTLLVEDILGDERFPRGTGLESGTRIQSVLCLPIVTAIGDLIGILELYRHWGKEAFCLSH
QEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAK
NLVNADRCALFQVDHKNKELYSDLFDIGEEKEGKPVFKKTKEIRFSIEKGIAGQVARTGE
VLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDEN
NFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTAEEWQGLMRFTLPVRLC
KEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKH
AVTVAHCMYAILQNNHALFTDLERKGLLIACLCHDLDHRGFSNTYLQKFDHPLAALYSTS
TMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMY
QTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQ
PIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLNQWEKVIRGE
ETATWISSPSVAQKTAASED
>Mus musculus_PDE10A(ENSMUSP_86485)
MEDGPSNNASCFRRLTECFLSPSLTDEKVKAYLSLHPQVLDEFVSESVSAETVEKWLKRK
TNKAKDEPSPKEVSRYQDTNMQGVVYELNSYIEQRLDTGGDNHLLLYELSSIIRIATKAD
GFALYFLGECNNSLCVFIPPGMKEGQPRLIPAGPITQGTTISAYVAKSRKTLLVEDILGD
ERFPRGTGLESGTRIQSVLCLPIVTAIGDLIGILELYRHWGKEAFCLSHQEVATANLAWA
SVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALF
QVDHKNKELYSDLFDIGEEKEGKPIFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADP
RFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCAL
ALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLMRFNLPARICRDIELFHFDIG
PFENMWPGIFVYMIHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAI
LQNNNGLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTV
SILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLHNQS
HRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKRD
EVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLNQWEKVIRGEETAMWISGPGP
APSKSTPEKLNVKVED
>Felis catus_PDE10A(ENSFCAP_11932)
MATLYGLTDEKVKAYLSLHPQVLDEFVSESVSAETVEKWLKRKNNKPEDESAPKEVSRYQ
DTNMQGVVYELNSYIEQRLDTGGDNQLLLYELSSIIKIATKADGFALYFLGECNNSLCVF
TPPGIKEGKPRLIPAGPIAQGTTISAYVAKSRKTLLVEDILGDERFPRGTGLESGTRIQS
VLCLPIVTAIGDLIGILELYRHWGKEAFCMSHQEVATANLAWASVAIHQVQVCRGLAKQT
ELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIG
EEKEGKPVFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNI
LCMPIVSRGSVIGVVQMVNKLSGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECI
YRVTMEKLSYHSICTAEEWQGLMHFNLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRS
CGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHGLFTDLERKGLL
IACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSS
EYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCS
VTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPC
YTTLTQIFPPTEPLLQACRNNLSQWEKVIRGEESAVWVSSQPGAHEPSEKLPVKMGD
>Gallus gallus_PDE10A(ENSGALP_18787)
MEDGSNSASCFRRFTDCFLNTRRRGSWMQQTTRSYVEGLTDEKVKAYLSLHPQVLDEFVS
ESVSAETVEKWLKRKNNRQEDESTPKEVSRYQDTNMQGVVYELNSYIEQRLDTGGDNQLL
LYELSSIIKIATKADGFALYFLGECNNSLCVFTPPGAKEGQPRLIPAGPIAHGTTVSAYV
ARSRKTLLVEDILGDERFPKGTGLESGTRIQSVLCLPIVTAIGDLIGILELYRHWGKEAF
HLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIM
IYAKNLVNADRCALFQVDHKNKELYSDLFDIGEENDGKPVFKKTKEIRFSIEKGIAGQVA
RTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSK
TDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSVCTAEEWQNLMHCTLP
PHIYKEIELYHFDISPHEDVWPAIFVYMVHQSCGTACFELEKLCRFTMSVKKNYRRVPYH
NWKHAVTVAHCMYAILQNNQGLFTDLERKGLLVACLCHDLDHRGYSNSYLQKFDHPLAAL
YSTSTMEQHHFSQTVSILQLEGHNVFSNLSSSEYEQVLEIIRKAIIATDLALYFGNRKQL
EELHQAGALNLKNQAHRDRVIGLMMTACDLCSVTKLWPVTRLTANDIYAEFWAEGDEMKK
TGIQPIPMMDRDKKDEVPQGQIGFYNAVAIPCYTTLAQIFPPTGPLLRACRDNLNQWEKV
TRGEEASIWITSQSVAPGTSDSLPVKTDD
>Anolis carolinensis_PDE10A(ENSACAP_3347)
MNCSQKIFFHWGKSGIRNKLEGLTDEKVKAYLSLHPQVLDEFVSESVSSETVEKWLRRKN
HIDEDVSTPKHVNRYQNSDMQGVVYELNSYIEQRLDIGVNNQLLLYELSGVIRMAINADG
FALYFLADCNNSLCVFTPPGIKDGQPQLIPVGPIQQGTTVSAYVAKSRETLLVEDILGDE
RFPKGTGLESGTRIKSVLCLPIVNAIGDLIGILELYRYWGNETFHLSHQEVATANLAWAS
VAIHQVEVSRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQ
VDEKNNELYSDLFDIGEEQEGKPVFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPR
FNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKLSGSAFSKTDENNFKMFAVFCALA
LHCANMYHRIRHSECIYRVTMEKLSYHSVCTEEEWQNLMDCKLPPHLCKEIELYHFDISP
YEDFWPAIFIHMIHQCCGIGWRISREDTQDKEECSAMLSALSLYVESDVVEEGFDLEKLC
RFTMSVKKNYRRVPYHNWKHAITVVHCMYAILQNNHTVFTDLERRGLLVACLCHDLDHRG
YSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSNLSSSDYEQVLEIIRKA
IIATDLALYFGNRKQLEELHQGRTLNFKNQAHRDRVIGLMMTACDLCSVTKLWHVTRLTA
SDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQIGFYNAVALPCYTTLAQILPPTA
PLLRACKENLKQWEKVIRGEEAYGWIPTQSNSTGSDSLPVKIDD
>Danio rerio_PDE10A(ENSDARP_27138)
MEDGPPSTSCFRRFTDCFLGSSLTDEKVKAYLSLHPQMLDEFVLESVSSETVDRWLKRKS
STQPADDSSAKEVSRYQDTNMQSVVYELNSYMEQRLDTGGDNKLLLYELCNIIKTATKAD
GFALYFLGECNNSLCLFTPTGAKEGLPGLIPSGPITFGTTIAAHVAKTRKTLLVEDIMGD
ERFPHGTGQDSGIRVHSVLCLPILTAIGDLIAILELHRHLGREPFNLSHQEVATANLAWA
SVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALF
QVDHNNKELYSDLFDIGEENEGKPVFRKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADP
RFNREVDLYTGYTTRNILCMPIVSRGTVIGVVQMVNKLGGSAFTKTDENNFKMFAVFCAL
ALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWKTLTQLTLPSAIYKEIELFHFDIA
PFEELWPAIFVYMVHNSCGKTSFELEKLCRFTMSVRKNYRRVPYHNWKHAVTVAHCMYAI
LQKTTGIFTELERKGLLIACLCHDLDHRGYSNSYLQKFDHPLAALYSTSTMEQHHFSQTV
SILQEGHNIFSNLTSGEYEQVLEIIRKAIIATDLALYFGNRKQLAELLSTGALDLNNRAH
RDRVIGLMMTACDLCSVTKLWPVTRLTANDIYAEFWAEGDEMKKIGMQPISMMDRDKKDE
VPQGQVGFYNAVAIPCYTTLSELFPPSVPLLEACRENLSQWERIVQGEDVSAWSSTEEAE
VSETSDSDQLKWTTESVAPFPQHHPQPARDTGLPVDSPTSCRDGRKCRGQADEDTFRKKI
NKT
>Takifugu rubripes_PDE10A(ENSTRUP_29340)
MEDGPSSTSCFRRLTDCFLGASLTDEKVKAYLSLHPQMLDDFVLESVSTETLDRWLKKKT
SSGPADDASAKEVSRQYQDTNMQGVVYELNSYMEQRLDTGGDNKLLLYELCNIIKTATKA
DGFALYFLGESNNSLCLFTPTGAKDGPPSLIPSGPIAFGTTIAAHVAKTRRTLLVEDIAG
DERFPDGTGQDSGIHVHSVLCLPILTAIGDIIAVLELHRHRGKEPFNLSHQEVATANLAW
ASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCAL
FQVDHNNKELYSDLFDIGEENEGRPVFRKTKEIRFSIEKGIAGQVARTGEVLNIPDAYAD
PRFNREVDLKTGYTTRNILCMPIVSRGTVIGVVQMVNKLSGCAFTKTDENNFKMFAVFCA
LALHCANMYHRIRQSECIYRVTMEKLSYHSICTSEEWKTLTQLNLPAPIYKEIEMFHFDI
NPFEEIWPAVFIYMVHNSCGKSSFELEKLCRFTMSVRKNYRRVPYHNWKHAVTVAHCMYA
ILQKTSGMFTELEKKGLLIACLCHDLDHRGYSNTYLQKFDHPLAALYSTSTMEQHHFSQT
VSILQLEGHNIFSNLNSSEYEQVLEIIRKAIIATDLALYFNNHQQLTELLSSEALDLNNY
SHRDRVIGLMMTACDLCSVTKKWQITRLTANDIYAEFWAEGDEMKKIGLQPIPMMDRDKK
DEVPQGQVGFYNSVAIPCYTTLSKLFPPSNPLLKACKENLSMWEKIACGEVEDVVTSPPY
DSGPVKGVEPTSRVAG
>Homo sapiens_PDE2A(ENSP_334910)
MGQACGHSILCRSQQYPAARPAEPRGQQVFLKPDEPPPPPQPCADSLQDALLSLGSVIDI
SGLQRAVKEALSAVLPRVETVYTYLLDGESQLVCEDPPHELPQEGKVREAIISQKRLGCN
GLGFSDLPGKPLARLVAPLAPDTQVLVMPLADKEAGAVAAVILVHCGQLSDNEEWSLQAV
EKHTLVALRRVQVLQQRGPREAPRAVQNPPEGTAEDQKGGAAYTDRDRKILQLCGELYDL
DASSLQLKVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTGCLGQVV
EDKKSIQLKDLTSEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKLEGDLFTD
EDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITE
ARNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPD
AYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAF
SIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNF
ASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMH
AFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYS
SEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDL
QKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAM
GNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSH
KFTIRGLPSNNSLDFLDEEYEVPDLDGTRAPINGCCSLDAE
>Macaca mulatta_PDE2A(ENSMMUP_19727)
QDALLSLGSVIDISGLQRAVKEALSAVLPRVETVYTYLLDGESRLVCEDPPHELPQEGKV
WFTDQDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQPPRPIQKGNAHVFLDCLMTWRP
AVAQDPRHCPQALYCSIWALQQHQLELVFDGGVVDDESYEIRIPADQGIAGHVATTGQIL
NIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDL
ATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDESTKLLHDGIQPVAAI
DSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYH
NWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLA
ALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRI
FKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDL
EKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPEAAELYERVASNREHWT
KVSHKFTIRGLPSNNSLDFLDEEYEVPDLDGTGAPINGCCSLDAE
>Mus musculus_PDE2A(ENSMUSP_127521)
MGQACGHSILCRSQQYPAARPAEPRGQQVFLKPDEPPPQPCADSLQDALLSLGAVIDIAG
LRQAARDALSAVLPKVETVYTYLLDGESRLVCEDPPHELPQEGKIREAVISQKRLSCNGL
GPSDLLGKPLARLVAPLAPDMQVLVIPLLDKETGSVAAVILVHCGQLSDSEEQSLQVVEK
HALVALRRVQALQQRRPEAVQNTSVDASEDQKDEKGYTDHDRKILQLCGELFDLDATSLQ
LKVLQYLQQETQATHCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTMGRLGQVVEDKQC
IQLKDLTSDDVQQLQNMLGCELQAMLCVPVISRATDQVVALACAFNKLGGDFFTDEDEHV
IQHCFHYTGTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLS
NAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHP
LFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCG
ISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFANFTY
TPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVS
HFCYLLYKNLELSNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSV
MERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAE
VGYDRNNRQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPM
EMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIR
GLPSNNSLDFLDEEYEVPDLDGTRAPVNGCCSLE
>Felis catus_PDE2A(ENSFCAP_12233)
MGQACGHSILCRSQQYPAARPAEPVLSRGWGLXXPPPPPQPCADSLQDALLSLGSVIHIA
GFQRAVKEALSAVLPKVETVYTYLLDGESRLVCEDPPHELPQEGKVREAVISRKRLGCNG
LGPSDLPGKPLARLMAPLAPDTQVLVMPLVDKEAGAVAAVILVHCGQLSDSEEWSLQAVE
KHALVALRRVQALQPRGPGAASAAVRNPPAGVAGDQKGGVAHTDQDQKILQLCGELYDLD
ASSLQLKVLQYLQQETQASRCCLLLVSEDNLQLSCKVIGDKVLEEETSFPLTTGRLGQVV
EDKKSIQLKDLTSEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKLGGDLFTD
QDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITE
ARNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPD
AYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAF
SIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNF
ASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMH
AFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYS
SEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDL
QKMAEVGYDRTNKQHHSLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAM
GNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSH
KFTIRGLPSNNSLDFLDEEYEVPQLDGTGAPVNGCFSLDAE
>Anolis carolinensis_PDE2A(ENSACAP_2806)
FQVSDDEYTKLLNENILPVSNIDTDFAKFTYTPRSLPDDDTSMAILSMLQDMNFISSYKI
DRQTLVRFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELVNYLEDIEIFALFISCM
CHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTQGCNIFDHFSRKDY
QRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDPKNKQHHSLLICLLMTSCDLSDQTK
GWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLL
QDLFPRSAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEYDLQTMGEDSEDSIR
MNGCLEDGHLEEGEELE
>Takifugu rubripes_PDE2A(ENSTRUP_23076)
QDALLRLAAVVDVHSLRAAFRDSVQDLLPHTECVCVYMLDGESRLICDEPPHELPKEGKI
RSIVNQLNRRQCNGLPLSELPEKYRACLAAPLPAHRRAIIIPILDQKQSEAIAVLLVGCN
SLSDQDEVHLNTLEKHTLVAHKRMNKITLPASSLPPQASSQPFFRTVHDALLHLDISGHD
YSQLDRDILQLCGELFDLDAASLQLKVINYLQQQTQSECCCLLLVSEDNHQLFCQVVGDK
VLEEEISFPLTFGHFGQVVQKKQSITLQDITAEECRQMSTMLGCKIMSMLCVPVASRATG
QVVALACAFNKQGGQRHTEADEHAIQHCFCYTSTVLTSTLAFQKEQKLKVECQALLQVAK
NLFTHLDDVSVLLQEIIVEARNLSGAEICSVFLLDRLSHELVAKVFDGGVVSDEEKEFRI
PADQGIAGHVATTGQILNIKDAYSHPLFYRGVDDSTGFRTRNILCFPIKDETNEVIGVAE
LVNKMNGPWFNRFDEDLATAFSIYCGISIAHSLLYKRVHEAQFRSHLANEMMMYHMKVSG
EEVSKLLVSGIEPIKEIDPCFAEFTYTPRSLSDDSTPMCVLSMFEDMGFINTYKIDLHTL
ARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLGLSRYLQDIEILALFVSCMCHDLD
HRGTNNSFQVASQSVLAALYSSEGSVMERHHFAQAIAILNTVGCNIFEKFSRKDYQRMLD
LIRDIILATDLAHHLRIFKDLQKMADDGYNPKSQTHRSMLLCLLMTSCDLSDQTKGWKTT
RKIAELIYKEFFSQGDLEKAMGNRPSEMMDREKAYIPELQISFMEHIAMPIYKLLSELFP
GAAELYERVAANREQWTKVSHKFTIRGLPSNNSLDFLDQEYELLQSEGALTSDDQCLNGC
LDDAE
>Homo sapiens_PDE3B(ENSP_282096)
MRRDERDAKAMRSLQPPDGAGSPPESLRNGYVKSCVSPLRQDPPRGFFFHLCRFCNVELR
PPPASPQQPRRCSPFCRARLSLGALAAFVLALLLGAEPESWAAGAAWLRTLLSVCSHSLS
PLFSIACAFFFLTCFLTRTKRGPGPGRSCGSWWLLALPACCYLGDFLVWQWWSWPWGDGD
AGSAAPHTPPEAAAGRLLLVLSCVGLLLTLAHPLRLRHCVLVLLLASFVWWVSFTSLGSL
PSALRPLLSGLVGGAGCLLALGLDHFFQIREAPLHPRLSSAAEEKVPVIRPRRRSSCVSL
GETAASYYGSCKIFRRPSLPCISREQMILWDWDLKQWYKPHYQNSGGGNGVDLSVLNEAR
NMVSDLLTDPSLPPQVISSLRSISSLMGAFSGSCRPKINPLTPFPGFYPCSEIEDPAEKG
DRKLNKGLNRNSLPTPQLRRSSGTSGLLPVEQSSRWDRNNGKRPHQEFGISSQGCYLNGP
FNSNLLTIPKQRSSSVSLTHHVGLRRAGVLSSLSPVNSSNHGPVSTGSLTNRSPIEFPDT
ADFLNKPSVILQRSLGNAPNTPDFYQQLRNSDSNLCNSCGHQMLKYVSTSESDGTDCCSG
KSGEEENIFSKESFKLMETQQEEETEKKDSRKLFQEGDKWLTEEAQSEQQTNIEQEVSLD
LILVEEYDSLIEKMSNWNFPIFELVEKMGEKSGRILSQVMYTLFQDTGLLEIFKIPTQQF
MNYFRALENGYRDIPYHNRIHATDVLHAVWYLTTRPVPGLQQIHNGCGTGNETDSDGRIN
HGRIAYISSKSCSNPDESYGCLSSNIPALELMALYVAAAMHDYDHPGRTNAFLVATNAPQ
AVLYNDRSVLENHHAASAWNLYLSRPEYNFLLHLDHVEFKRFRFLVIEAILATDLKKHFD
FLAEFNAKANDVNSNGIEWSNENDRLLVCQVCIKLADINGPAKVRDLHLKWTEGIVNEFY
EQGDEEANLGLPISPFMDRSSPQLAKLQESFITHIVGPLCNSYDAAGLLPGQWLEAEEDN
DTESGDDEDGEELDTEDEEMENNLNPKPPRRKSRRRIFCQLMHHLTENHKIWKEIVEEEE
KCKADGNKLQVENSSLPQADEIQVIEEADEEE
>Macaca mulatta_PDE3B(ENSMMUP_1027)
MRRDERDAKAMRSLQQPDGAGSPPESLRNGYVKSCVSPLRQDPPRGFFFHLCRFCNVELR
PPPASPQQPRRGSPFCRARLSLGALAAFVLALLLGAEPESWAAGAAWLRTLLSVCSHSLS
PLFSIACAFFFLTCFLTRTKRGPGPGRSGGSWWLLALPACCYLGDFLVWQWWSWPWGDGD
AGSPATHTPPEAAAGRLLLVLSCVGLLLTLAHPLRLRHCLLVLLLASFVWWVSFTSLGSL
PSALRPLLSGLVGGAGCLLALALDHFFQIREAPLHPRLSSAAEEKVPVIRPRRRSSCVSL
GETAASYYGSCKIFRRPSLPCISREQMILWDWDLKQWYKPHYQNSGGGNGVDLAVLNEAR
NMVSDLLIDPSLPPQVISSLRSISSLMGAFSGSCRPKINPLTPFPGFYPCSEIEDPAEKG
DRKLNKGLNRNSSPTPQLRRSSGTSGLLPVEQSSRWERNNGKRPHQEFGISSQGCYLNGP
FNSNLLTIPKQRSSSVSLTHHVGLRRAGVLSSLSPVNSPNYGPMAAGSLTNRSPIEFPDT
ADFLNKPSIILQRSLGNAPNTPDFYQHLRNSDSNLCNNCGHQILKYVSTSESDSTDCCSG
KSGEEENIFSKESFKLMETQQEEKTEKKDSRKLFQEGDNWLTEESQNEQQTNIEQEVSLD
LILVEEYDSLIEKMSNWNFPIFELVEKMGEKSGRILSQVMYTLFQDTGLLEIFKIPTQQF
MNYFRALENGYRDIPYHNRIHATDVLHAVWYLTTRPVPGLQQIHNGCGTGNETDSDGRIN
RGRIAYISSKSCSIPDESYGCLSSNIPALELMALYVAAAMHDYDHPGRTNAFLVATNAPQ
AVLYNDRSVLENHHAASAWNLYLSRPEYNFLLHLDHVEFKRFRFLVIEAILATDLKKHFD
FLAEFNAKANDVNSNGIEWSNENDRLLVCQVCIKLADINGPAKVRDLHLKWTEGIVNEFY
EQGDEEANLGLPISPFMDRSSPQLAKLQESFITHIVGPLCNSYDAAGLLPGQWIEAEEDN
DTESGDDEDGEELDTDDEEMENNLNPKPPRRKSRRQIFCQLMHHLTENHKIWKEIIEEEE
KCKADGNKLQVENSSLPQADEIQVIEEADEEEERQFE
>Mus musculus_PDE3B(ENSMUSP_32909)
MRKDERERDAPAMRSPPPPPASAASPPESLRNGYVKSCVSPLRQDPPRSFFFHLCRFCNV
EPPAASLRAGARLSLGVLAAFVLAALLGARPERWAAAAAGLRTLLSACSLSLSPLFSIAC
AFFFLTCFLTRAQRGPGRGAGSWWLLALPACCYLGDFAAWQWWSWLRGEPAAAGRLCLVL
SCVGLLTLAPRVRLRHGVLVLLFAGLVWWVSFSGLGALPPALRPLLSCLVGGAGCLLALG
LDHFFHVRGASPPPRSASTAEEKVPVIRPRRRSSCVSLGESAAGYYGSGKMFRRPSLPCI
SREQMILWDWDLKQWCKPHYQNSGGGNGVDLSVLNEARNMVSDLLIDPSLPPQVISSLRS
ISSLMGAFSGSCRPKINSFTPFPGFYPCSEVEDPVEKGDRKLHKGLSGRTSFPTPQLRRS
SGASSLLTNEHCSRWDRSSGKRSYQELSVSSHGCHLNGPFSSNLFTIPKQRSSSVSLTHH
AGLRRAGALPSHSLLNSSSHVPVSAGSLTNRSPIGFPDTTDFLTKPNIILHRSLGSVSSA
ADFHQYLRNSDSNLCSSCGHQILKYVSTCEPDGTDHPSEKSGEEDSSVFSKEPLNIVETQ
EEETMKKACRELFLEGDSHLMEEAQQPNIDQEVSLDPMLVEDYDSLIEKMNNWNFQIFEL
VEKMGEKSGRILSQVMYTLFQDTGLLETFKIPTQEFMNYFRALENGYRDIPYHNRVHATD
VLHAVWYLTTRPIPGLPQIHNNHETETKADSDGRLGSGQIAYISSKSCCIPDMSYGCLSS
NIPALELMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYNDRSVLENHHAASAWNLYLS
RPEYNFLLNLDHMEFKRFRFLVIEAILATDLKKHFDFLAEFNAKANDVNSNGIEWSSEND
RLLVCQVCIKLADINGPAKDRDLHLRWTEGIVNEFYEQGDEEATLGLPISPFMDRSSPQL
AKLQESFITHIVGPLCNSYDAAGLLPGQWIETEEGDDTESDDDDDDDDGGGEELDSDDEE
TEDNLNPKPQRRKGRRRIFCQLMHHLTENHKIWKEIIEEEEEKCKAEGNKLQVDNASLPQ
ADEIQVIEEADEEEEQMFE
>Felis catus_PDE3B(ENSFCAP_19173)
MILWDWDLKQWYKPHYQNSGGGSGVDLSVLNEARNMVSDLLIDPTLPPQVISSLRSISSL
MGAFSGSCRPRINPLTPFPGFYPCSEVEDPAEKGDRKLHKGLHSRNSLPTPQLRRSPGTS
GLPPIEQSSSRWERSNGKRPHQEFGISSQGSYLNGPLSSNLLTMPKQRSSSVSLTHHIGL
RRAGAFPSLSPVNSPSHGPVSAGSLMNRSPVEFPATASSLTKPSVILHRSLGSAPNSPDF
YQHVRNSDSSLCNSCGHQILKYVSTSESESGIDCHSGKSGDEDNTVSSKQSFSLTEVQHE
VETENTDCRKLFLEGDTHLTEEAQNEQQPNIEQEASLDLILIEDYDSLIEKMSNWNFQIF
EVVEKMGEKSGRILSQVMYTLFQDTGLLEIFKIPTLQFMNYFRALENGYRDIPYHNRIHA
TDVLHAVWYLTTRPIPGLQQIHNDHATGNETDSDGRMNPGQMAYISSRSCSIPDESYGCL
SANIPALELMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYNDRSVLENHHAASAWNLY
LSRPEYNFLLNLDHVEFKRFRFLVIEAILATDLKKHFDFLAEFNAKANDVNSNGIEWSNE
NDRLLVCQVCIKLADINGPAKVRDLHLKWTEGIVNEFYEQGDEEANLGLPISPFMDRSSP
QLAKLQESFITHIVGPLCNSYDAAGLLPGEWIEAEEDEDAESCYDEEEGEELDTDDEEIE
DNLNPKPRRRKGRRRIFCQLMHHLTENHKIWKEIIEEEEKCKADGNKLQVENSSLPQADD
IQVIEEADEEEERQFE
>Gallus gallus_PDE3B(ENSGALP_3882)
MILWDWDLKQWYKPYYQNAGSGTGVDLSVLNEARSMLTDLLTDPSLPPQVISSLRSINSL
IGAFSGTCRPKANPFTPFPGFFPCPEVDDPAEKGDRKPLKGLISRNSLPTPQLRRSSGVS
GIPPIESPSSKWERSNSKRPHQDYNVSSQGSHSNGSFGANLLAIPKQRSSSLTLAHHMGS
RRAGASPGLSPVGSPTHGSVSSGSWSPVEFPDTADFLTKPSININKPPAHTFSSPDYQQQ
VKTPVGYVCSSCGRQILKPIPSLEEEFVEYKDKKSGEVGSSSLSKEPFHQAEETKDEKKE
IITQTQNNSLVVQSPKLETMITEHESLMEKMNNWNFQIFDLVQEMGDQSGRILSRVTYTL
FEDTGLFEIFKIPIKEFMNYFCALEDGYRDIPYHNRIHATDVLHAVWYLTTRPIPGFQQI
HNEHVLATDMDEAGGGVHDQVSYISSKSCSITDDSYGCLASNIPALELMALYVAAAMHDY
DHPGRTNAFLVATNAPQAVLYNDRSVLENHHAASAWNLFLSRPEYNFLSNLDHVEFKRFR
FLVIEAILATDLKKHFDFLAEFNSKANDIDSHGIEWSNENDRLLVCQICIKLADINGPAK
VRELHLKWTEGIVNEFYEQGDEEASLGLPISPFMDRSSPQLAKLQESFITHIVGPLCNSY
NAAGLLPGQWVDEEEGAESNEDDDGAQLESDDEEIEDDLILKAQRRKGRRIFCQLIHHLS
ENHKIWKKAIEEEEKAEGAKLLTEISSLPQADEIQVIEEADEEDERQLGEEKTC
>Anolis carolinensis_PDE3B(ENSACAP_12439)
MNSRNSLPTPQLRRSSGATGLLPIEPSSRWDRSTGKRVHLEYNSSSQGSYPNGPLNTNLL
TIPKQRSSSVTLAHSIGSKRAGTSQNPIPMTSPSSGFIFGGYHRSPVEFPDTADFLTKPS
INMNKSLGCTFSSSEFQQQIRTSSHYTCSSCGRQLFKSVAASLSESVAEYQNHKTGEDGN
TDVSKDSAHFIEKQQSETGEIKNHNNWMDQTKKLMALEDHDSLIEKMNTWNFQIFDLVKR
MGDKSRRILSQVAFTLFQDTGLFESFKIPTRQFMNYFQALENGYRDIPYHNRIHATDVLH
AVWYLTTRPIPGFQQIHSVSVTGADSDTENGILAGHVSYVSSKSCTILDENYGCLASNIP
ALELMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYNDRSVLENHHAASAWSLFLSQPE
YNFLPNLDHVQFKRFRFLVIEAILATDLKKHFDFLAEFNAKVNDINGHSIEWSSESDRLL
VCQICIKLADINGPAKVRDLHLKWTEGIVNEFYEQGDEEASLGLPISPFMDRHSPQLAKL
QESFITHIVGPLCNSYDAARLLPGQWVDEKDNESSDEYDAGELDSEEDEIDDFGTKLQRR
KRQQIFCQLIHHLNENHKIWKKITEEEELNKSEESKQAENTSLGQSDEIQVIEEADEEEE
HHQGEEKTF
>Danio rerio_PDE3B(ENSDARP_84073)
MAVREEGEVLHSKIRQQQHDGVVGNANSAESFRNGYVKSCVTPLKQDHPRGFLFNVCRFC
NEDILKSKLFRGSAIYVGALAVLALSCFVSRSFQSEHGVLELRTFLLDFSQSVSPLFSIG
CAYFFLTLYLRRTKRESSRCWLLSLPASCYLGDLMVVRLLQWGEEHHQMQMMGRLLFVLG
CVGLLTLVPTLKLKHSVLILVFASLVWLLSFTSLGCLSPSLRPVLSCVAGVSGSLLALCF
DHYYPPRESAGRVPNAEEKVPVIRPRRRSSCVSLGETSTSYYGSCKMPRRPSLPCISREQ
MILWDWDLKQWYKPQYQGAVSGNGVDLSVINEARNLVSELLMDPSLSPHALSSLRSVSSL
MGAFSGSCRPRVNPFTPFPGFYPCAEMDDPSERGERKPVKGLSSRNSLPTPQLRRSSASS
SLPPLDPASSRWERTNGKRSHSELSSFVSNGPNSNLLTIPKQRSSSVTLSYGHTLSRRPG
ASPSLSPVTSPSHSPPAGPGSSLVTRSPVEFPDTADFLTKPSVNLHKPLGYTMSSPDFQQ
QYRTSASTPLCTSCGRQMLKGVPSVEVVEGHHTTANEMQRTRSADGAEYGGENLIREESL
EAESQEERTSDTAGEKVNSQPEEEEQTSSTEQSSLDPEGDEEFRLDLMLVEHEELMEKIN
TWNFQIFELMDLTGGKTGRILSYVAYTLFQDTGLFEIFKIPVREFMTYFCALENGYRDIP
YHNRVHATDVLHAVWYLTTQPIPGFQQIHNEHVTGSDTDSDSGISPGRVAYATSKSSSFQ
DDSYGCLAWNVPALELMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYNDRSVLENHHA
ASAWSLFLSRPEFNFLCNLDHVEFKRFRFLVIEAILATDLKKHFDFLAEFNSKVNDVNSP
GIDWTNENDRLLVCQVCIKLADINGPAKDRSLHLKWTEGIVNEFYEQGDEEGTLGLPISP
FMDRSAPQLAKLQESFITHIVGPLCNSYDAAGLLPGYWIDEEGSDDEEETEDNETEDEEL
DEDLEPKRRKRRRRLFCNIMQHLTENHKVWKKTIEEEEKAKELETQQKQQQQQQSEGPSL
PPSTSSSDDIQVIQEEAEEEERQ
>Takifugu rubripes_PDE3B(ENSTRUP_44336)
RPVVPTVASADMILWDWDLKHWYKPQYQGASTGNGVDLSVINEARNLVSDLLMDSSLPPQ
SVSTLRSISSLMGTFSGSCRPRVNPFTPFPGFYPCDEVEDSAERSERKSIKGLSSRNSLP
TPQPRRSSTSSSCSTLPSLDSASARWERNTGKRSHPDLNLSSPGLSNGPNANLLTIPKQR
SSSVTLTYHAGPRRSGASPSLSPVASPAHSPVAMGMGSTSSLIRPPVEFPDTADFLTKPS
VSLNLHKPLASTLSSPDFQQAFRGAAFPVCTSCGRQIAKGGDTSRLPFSNEAQRRREESV
EMEASADGRQDAAGKLVQTEEEEEEEAAEESSSTEQPTQEAEVEQEFILDPVLEEHETFM
EKMNTWNFQIFELVDKTGGKTGRILSYVTYTLFQDACLFEIFKIPVREFMTYFSALESGY
RDIPYHNRVHAADVLHAVWYLTTRPIPGFQQIHSEHVTGSDTGGMISYASSKSCSISDDS
YGCLAWNIPALELMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYNDRSVLENHHAAAA
WSLYLSQPEFNFLVNLDHVEFKRFRFLVIEAILATDLKKHFDFLAEFNSKVNDVNSPGID
WTNENDRLLVCQVCIKLADINGPAKIRDLHLKWTEGIVNEFYEQGDEEAKLGLPVSPFMD
RSSPQLAKLQESFITHIVGPLCNSYDAAGLLPGYWINQEGSDEDDEEGQVETDTDEEEDD
EMEDELEPTAERRKSRRRLFCSIMQHLAENHKVWKKTIEEEEKSKELGKPQQQPDSLPSS
LPTSPSDDIQVIQEEEEGEECDERMSGEEGSA
>Homo sapiens_PDE3A(ENSP_351957)
MAVPGDAARVRDKPVHSGVSQAPTAGRDCHHRADPASPRDSGCRGCWGDLVLQPLRSSRK
LSSALCAGSLSFLLALLVRLVRGEVGCDLEQCKEAAAAEEEEAAPGAEGGVFPGPRGGAP
GGGARLSPWLQPSALLFSLLCAFFWMGLYLLRAGVRLPLAVALLAACCGGEALVQIGLGV
GEDHLLSLPAAGVVLSCLAAATWLVLRLRLGVLMIALTSAVRTVSLISLERFKVAWRPYL
AYLAGVLGILLARYVEQILPQSAEAAPREHLGSQLIAGTKEDIPVFKRRRRSSSVVSAEM
SGCSSKSHRRTSLPCIPREQLMGHSEWDHKRGPRGSQSSGTSITVDIAVMGEAHGLITDL
LADPSLPPNVCTSLRAVSNLLSTQLTFQAIHKPRVNPVTSLSENYTCSDSEESSEKDKLA
IPKRLRRSLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSTSIKLQEAPSSSPDSWN
NPVMMTLTKSRSFTSSYAISAANHVKAKKQSRPGALAKISPLSSPCSSPLQGTPASSLVS
KISAVQFPESADTTAKQSLGSHRALTYTQSAPDLSPQILTPPVICSSCGRPYSQGNPADE
PLERSGVATRTPSRTDDTAQVTSDYETNNNSDSSDIVQNEDETECLREPLRKASACSTYA
PETMMFLDKPILAPEPLVMDNLDSIMEQLNTWNFPIFDLVENIGRKCGRILSQVSYRLFE
DMGLFEAFKIPIREFMNYFHALEIGYRDIPYHNRIHATDVLHAVWYLTTQPIPGLSTVIN
DHGSTSDSDSDSGFTHGHMGYVFSKTYNVTDDKYGCLSGNIPALELMALYVAAAMHDYDH
PGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLINLDHVEFKHFRFL
VIEAILATDLKKHFDFVAKFNGKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKCKEL
HLQWTDGIVNEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCNSYDSAG
LMPGKWVEDSDESGDTDDPEEEEEEAPAPNEEETCENNESPKKKTFKRRKIYCQITQHLL
QNHKMWKKVIEEEQRLAGIENQSLDQTPQSHSSEQIQAIKEEEEEKGKPRGEEIPTQKPD
Q
>Macaca mulatta_PDE3A(ENSMMUP_10834)
MAVPGDAARVRDKPVHSGVSQAPTAGRDCHHRAEPASPRDSGCRGCLGDLVLQPLRRSRK
LSSALCAGSLSFLLALLVRLVRGEVGCDLEQCKEAAAEEEEEAAPGAEGGVFPGPRGGAP
GGGARLSPWLQPSALLFSLLCAFFWMGLYLLRAGVRLPLAVALLAACCGGEALVQIGLGV
GEDHLLSLPAAGVVLSCLAAATWLVLRLRLGVLMIALTSAVRTVSLISLERFKVAWRPYL
AYLAGVLGILLARYVEQILPQSAEAAPREHLGSQLIAGTKEDIPVFKRRRRSSSVVSAEM
SGCSSKSHRRTSLPCIPREQLMGHSEWDHKRGSRGSQSSGTSITVDIAVMGEAHGLITDL
LADPSLPPNVCTSLRAVSNLLSTQLTFQAIHKPRVNPVTSLSENYTCSDSEESSEKDKLA
IPKRLRRSLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSTSIKLQEAPSSRWHTAP
AGRLTHYIWLEVSFEYGKANHVKAKKQSRPGALAKISPLSSPCSSPLQGTPASSLVSKIS
AVQFPESADTTVKQSLGSHRALTYTQSAPDLSPQILTPPVICSSCGRPYSQGNPADEPLE
RSGVATRTPSRTDDTAQVTSDYETNNNSDSSDIVQNEDETECLREPLRKASACSTYAPET
MMFLDKPILAPEPLVMDNLDSIMEQLNTWNFPIFDLVENIGRKCGRILSQVSYRLFEDMG
LFEAFKIPIREFMNYFHALEIGYRDIPYHNRIHATDVLHAVWYLTTQPIPGLSTVISDHG
STSDSDSDSGFTHGHMGYVFSKTYNVTDDKYGCLSGNIPALELMALYVAAAMHDYDHPGR
TNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLVNLDHVEFKHFRFLVIE
AILATDLKKHFDFVAKFNGKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKCKELHLQ
WTDGIVNEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCNSYDSAGLMP
GKWVEDSDESGDTDDPEEEEEEAAAPNEEETCENNESPKKKTFKRRKIYCQITQHLLQNH
KMWKKVIEEEQRLAGVENQSLDPTPQSHSSEQIQAIKEEEEEKGKPRGEKIPTPKPDQ
>Mus musculus_PDE3A(ENSMUSP_38749)
MAVRGEAAQDLAKPGLGGASPARVARGNHRHRGESSPSPRGSGCCWRALALQPLRRSPQL
SSALCAGSLSVLLALLVRLVGGEVGGELEKSQEAAAEEEEEEGARGGVFPGPRGGAPGGG
AQLSPWLQPAALLFSLLCAFFWMGLCLLRAGVRLPLAVALLAACCAGEALVQLSLGVGDG
RLLSLPAAGVLLSCLGGATWLVLRLRLGVLMVAWTSVLRTVALVSLERFKVAWRPYLAYL
AAVLGLLLARYAEQILPQCSGPAPPRERFGSQLSARTKEEIPGWKRRRRSSSVVAGEMSG
CSGKSHRRTSLPCIPREQLMGHSEWDHKRGPRGSQSGTSITVDIAVMGEAHGLITDLLAD
PSLPPNVCTSLRAVSNLLSTQLTFQAIHKPRVNPTVTFSENYTCSDSEEGLEKDKQAISK
RLRRSLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSASIKPHEAPSPSAVNPDSWN
APGLTTLTKSRSFTSSYAVSAANHVKAKKQNRPGGLAKISPVPSPSSSPPQGSPASSPVS
NSASQQFPESPEVTIKRGPGSHRALTYTQSAPDLSPQIPPPSVICSSCGRPYSQGNPADG
PSERSGPAMLKPNRTDDTSQVTSDYETNNNSDSSDILQNEEEAECQREPQRKASACGTYT
SQTMIFLDKPILAPEPLVMDNLDSIMDQLNTWNFPIFDLMENIGRKCGRILSQVSYRLFE
DMGLFEAFKIPVREFMNYFHALEIGYRDIPYHNRIHATDVLHAVWYLTTQPIPGLPSVIG
DHGSASDSDSDSGFTHGHMGYVFSKMYHVPDDKYGCLSGNIPALELMALYVAAAMHDYDH
PGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLVNLDHVEFKHFRFL
VIEAILATDLKKHFDFVAKFNAKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKCKEL
HLRWTEGIASEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCHSYDSAG
LMPGKWVDDSDDSGDTDDPEEEEEEAETPHEDEACESSIAPRKKSFKRRRIYCQITQHLL
QNHMMWKKVIEEEQCLSGTENQSLDQVPLQHPSEQIQAIKEEEEEKGKPRAEETLAPQPD
L
>Felis catus_PDE3A(ENSFCAP_905)
MGHSEWDHKRGPRGSQSSGTSITVDIAVMGEAHGLITDLLADPSLPPNVCTSLRAVSNLL
STQLTFQAIHKPRVNPVISFSENYTCSDSEENSEKDKLAIPKRLRRSLPPGLLRRVSSTW
TTTTSATGLPTLEPAPVRRDRSASIKLHEAPSSSAVCPDSWNNPVMMTLTKSRSFTSSYA
VSAANHVNSKKPNRPGALAKISPLSSPCSSPPQGTPASSPVSKISAVQFPESANTAAKQG
LSSHRALTYTQSAPDLSPQILPPPVICSSCGRPYPQGTPAAVPLERSSAAIRTPSRTDDT
TQVTSDYETNNNSDSSDIVQNEDETECPREPLRKASACGTYTSETMIFLDKPVLAPEPLV
MDNLDSIMEQLNTWNFPIFDLVEKIGRKCGRILSQVSYRLFEDMGLFEAFKIPVREFMNY
FHALEIGYREIPYHNRIHATDVLHAVWYLTTQPIPGHSTVINDHGSASDSDSDSGFTHGH
MGYVFSKMYNVPDDKYGCLSGNIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVL
YNDRSVLENHHAAAAWNLFMSRPEYNFLVNLDHVEFKHFRFLVIEAILATDLKKHFDFVA
KFNAKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKCKELHLQWTEGIVNEFYEQGDE
EASLGLPISPFMDRSAPQLANLQESFISHIVGPLCNSYDSAGLMPGKWVEDSDESGDTDD
PEEEEEEEEAPNEEETCENNEAPNFYRNNSFSLNRRVQCIYXQHLLQNHKMWKKVIEEEQ
RLAGIESQSLDQSPQQHSSEQIQAIREEEEEKGKPRGEEIPTL
>Gallus gallus_PDE3A(ENSGALP_36646)
MGHSEWDHKRGPRGSQSSGTSITVDIAVMGEAHGLITDLLADPSLPPNVCTSLRTVSNLL
NTQLTFQAIHKPRVNPLVSFSENYTCSDSEECPEKGEKLAIPKRLRRSLPPGLLRRVSST
WTTTTSATGLPTLEPAPVRRDRSASIKPHESSSSSKVNSTDSWNSSLLMTITKSRSFSTS
YAMSPTNHLNAKRQSRQGIPPNISPLTSPCHSPLQGTPATSPTGKTSSVSFPDSTDTDTK
QGLKPHKVLTATQSAPSLSEPNISPSVICSSCGRPYNQIEAGDGTLDRSDGTTHTLNRTD
DPAQATSDYETNNSDSSDIVQNDDETDCSKEKARKGSVCRTYAPETIILQDKPVLAPEPL
VMDNLDPLMEQLNSWNFPIFDLVEKIGKKCGRILSQVSYRLFEDMGLFETFKIPVREFMN
YFHALECGYREIPYHNRIHATDVLHAVWYLTTQPIPGLPTVINDHGSASDSDSDSGITHG
HMGYVFSKTYTPTDDSYGCLAGNIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAV
LYNDRSVLENHHAAAAWNLFMSRPEYNFLVNLDHVEFKHFRFLVIEAILATDLKKHFDFV
AKFNAKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKCKDLHLQWTEGIVNEFYEQGD
EEASLGLPISPFMDRSAPQLAHLQESFITHIVGPLCNSYDSAGLMPGKWIEDSDESGDTD
EHEEEETAEMETCENAESRKKKFKRRKIYCQITQHLLQNHKMWKKVIEDEERLAGTEKQG
AEQSTLHPSSEQIQAIREEDEEKGKPKRDEEENTTVEPNQ
>Anolis carolinensis_PDE3A(ENSACAP_17252)
MGHSEWDHKRGPRGSQSSGTSITVDIAVMGEAHGLITDLLADPSLPPNVCTSLRAVSNLL
NTQLTFQAIHKPRVNPLASFSENYSCSDSEECSEKGEKLKRIRKNLPPGLLRRVSSTWTT
TTSATGLPTLEPAPVRRDRSASIKLHDTSSSSSDSWNNPLLMSITKSRSFSASYAMSAAN
HLNSKRPSRQGIPPNISPLTSPSHSPIHGTPAHSPTSKTSNEQFPESTVTASKQTLKPHK
VLGCTQSAPAIAEPVLPSPVICSSCGRPYNQIEPGEGTLDRSDGTAHTLNRTDDPAQATS
DYETNNSDSSDIVQNDDETDCSKEQAQMDSNCRTYTPETIILHPLLPSEEKPILAPEPLI
MDNLDPLMDQLNNWNFPIFDLVDKIGKKCGRILSQVSYRLFEDMGLFETFKIPVKEFMNY
FHALECGYREIPYHNRIHATDVLHAVWYLSTQCIPGLPTVINDHGSASDSDSDSGITHGH
MGYVLSKTYAPADDTYGCLAGNIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVL
YNDRSVLENHHAAAAWNLFMSRSEYNFLVNLDHVEFKHFRFLVIEAILATDLKKHFDFVA
KLNAKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKHKDLHLRWTEGIVNEFYEQGDE
EASLGLPISPFMDRSAPQLANLQESFITHIVGPLCNSYDSAGLMPGKWVEDNDDLGDTDD
PDEEDSTDMDTCENPESRKKRRKIFCQITQHLVENHQMWKKVIEEEERKAGIEKQALEQP
ATLHPSSEQIEAIKEEEEEKGKPKPEEDSTIPETNQ
>Danio rerio_PDE3A(ENSDARP_119110)
MALESVRNGYVRTCVTPVEQDCWHSCLRSRRSLSSAVCVASLSVLLALLWDAERTHAHSG
SHLVTLVELVWQLLSPVLTLVCAFFWVGVYLLRCGVLIRTAVFLLTVCHLGEAAAQSLLD
AQQLYSFTATALVLLACLASGALMVVRLGQGISVLLFISIIRTVSLLSLQKVRASWRPYL
AYLLGLLGVLLARYADRLLPEQGASHREGSRGDIPVFKRRRRSSSVVSSDMAQHGQSRSK
SHRRTSLPCLQREQMLPQQEWDNKRGARGSQSSGTSVTVDIAVMGEAHGLISDLLADQSL
APNICSTLRAVSNLLNTQLTFQPLHHRPRLGPLLAFSDGHTCSDSEEAPEKGERLAIPKR
LRRSLHPGLLRRISSTWTTTTSATGLPTLEPGPVRRDRSASIKAPHDGPSSSLVNSDSWN
NSNMLSISKSRSMSASYAASSNTTNHIYSKSRRGCSSSTISPLASPCHSPPVQSSPLTSP
TNKTPSVELPDPELPPPRSPHKALTHSQSAPSSSAALWPPPTPLCSSCGRPYSKQRHSDG
STEPAERTQQSDEPAMMSSDYDSTYETNHSDSSDFAQTDEDREARRTLTLATLIPAEEKP
ILAPEPLLMEGLEPLLCQINNWNFPIFSLVEKTNGRCGCILSQMSYRLFVDTGLFETFKI
>Takifugu rubripes_PDE3A(ENSTRUP_43548)
LFTLLCAFFWVGVYLIRCGVLIRTTLSLLTLCHLGAAAAWSLLDGTDEQLFSFTTAAVVV
LVCVATGALMVARLNQGISVILYISIVRTVSLFSLHKVRANWRPYVAYLVGVLGILLARY
ADELLPNQGRHKEGCTPVTGAREEIPVFKRRRRSSSVIASDMAHSQSSSKSHRRTSLPCI
QRDQMLSRSEWDHKRGSRGSQSSGTTVMVDIAVMGEAHGLITDLLADPSLPANTSTSLRA
VSKLLSTQLTFQPLHRPRPVPLLSPSDAYTLSDSEDGPEKGEKTSIHKRLRRSLHPGLLR
RISSTWTTTTSATGLPTIEPGPVRRDRSASIKQYHETLTCSEGRAANASSFQWDLAKTAP
RFRGAGEELFNDSCSVNPCSSANGPRLQGPIQLSAPSQKTEKRIGGASASSSTFIKSISC
PEKAGFTTFRGCRYYSLPRRQSVAFLCALKIPSLLVHICGRSYIKLSHGEGSLDKGDRLP
RSAEDHVVVSSDYDSTHEANHSDSSDVAHTEEDTEEGKSSAQNVILHQLIPPEDKPILAP
EPLLMEDLDPWMSQLNNWNFPIFTLMEKTNGKCGQVLSQVAYRLFEDTGLFETFKIPVKE
FMNYFHALENGYRDIPYHNRIHATDVLHAVWYLTTQAVPGLPSLVADHGSASDSDSDSGI
THSHMGFLVSKTYTVSEDGYGCLSGLIPALELMALYVAAAMHDYDHPGRTNAFLVATSAP
QAVLYNDRSVLENHHAAAAWNLFMSHPEYNFLVNLDHVEFKRFRFLVIEAILATDLKKHF
DFLAEFNAKVGDDPSTGIDWSNENDRLLVCQMCIKLADVNGPLKCKDLHLQWTEGIVNEF
YQQGDEESSMGLPISPFMDRAAPQLAKLQESFITHIVGPLCNSYDSASLIPGRWVEPNPE
ADEPESTENEEDEEDTAEEDISTSSETSQKAAPKKRRKVFCHITQHLLENHEMWKKVIAE
DAQKQAQGGESVLLNNVAEPILAIHEEEEEPGSREELAEGEEPEE
>Gasterosteusaculeatus_PDE3Aa(ENSGACP_13254)
WVRLMFSKIRSSHRIRSVVCVGSLSLLLALLVKCADWRAETSSSADNRLSHTSSLFHLVS
GCAAELLQTCWSVVPPPLTLACAFFWVGVYLIRCGVLIRTVVSLLTLCHLGEAAARSLLD
GTDERLFSFATAAVVVLVCVAAGSLMVARLNQGISVVVFISLVRTISLFSLHKVRATWRP
YVAYLVGVLGILLVRYADKLLPNQGRHKEGCTPVTGAREDIPVFKRRRRSSCVVASDMAH
SQSNSKSRRRTSLPCIQRDQMLPRSEWDYKRGSRGSQSSGTTVMVDIAVMGEAHGLITDL
LADPSLPPNTCTSLRAVSNLLTTQLTFQSLHRPRPASLLNPGDAYTFSDSEEGPEKGEKT
SIHKRLRRSLPPALLRRISSTWTTTTSATGLPTIEPGPVRRDRSASIKPFHEALTCRYHH
SNKPSKSTCSKSLSNAKTYMTHSTVFSTRRPGKKGPIESPLRSSEPPARELLSSSPSISF
PKEAAFTTFGESYGQPRLALSTNIWRTGLRLTPNVFYSNIFCRFGCGRPYIKLSHGEGSI
DKGDRIPRSAEDQAVVSSDYESTHEANHSDSSDVAHTEEDTEEGKNPGQNVILHPLIPPE
HLSQDQPILAPEPLVMEDLQPLMSQLTNWNFPIFSLMEKTNGKCGRILSQVSYRLFEDTG
LFETFKIPVNEFMNYFHALENGYRDIPYHNRVHATDVLHAVWYLTTQAVPGLPSLITDHS
SASDSDSDSGITHSRVGFLVSKTYTVSEDGYGCLSGLIPALELMALYVAAAMHDYDHPGR
TNAFLVATSAPQAVLYNDRSVLENHHAASAWNLFMSRPEYNFLVNLNHGEFKRFRFLVIE
AILATDLKKHFDFLAEFNAKVGDDPSTGIDWSNENDRLLVCQMCIKLADINGPLKCKDLH
LQWTEGIVNEFYEQGDEESSLGLPISPFMNRAAPQLAKLQESFIAHIVGPLCNSYNSASL
IPGRWVEPNHTSTSSEASRKNNVVVQSYEAKVVAQLSISFPEKGTSKKRRKVFCQITYHL
LENHEMWKKVIAVEAQQQGQGAESVHLNNVAEPILAIHEEEEEPGSREELVEGEDLEE
>Gasterosteusaculeatus_PDE3Ab(ENSGACP_11543)
YCVHPVCALACAFFWGGLYLLRCGVLIRTAVFLLAVCLLGEAAAQFLLRGAEEEQLLSHP
ATLVVLGCLGSGALLVVRLRQGVSIVVFVSVIRAASVVSLGSLRASWRPYLAYLLGLLGV
LLARYADRLRPAPGTSGTGCCGSVTGAKEEDIPVFKRRRRSSSISASEMMAHSQSNSKSH
RRTSLPCIPRDQLHIMCQPEWDFKRALSRSQPSSTSVVVDIAVMGEARGLISDLLADPSL
PPNTCSSLKAVSNLLGTQISLQPLHRLRIPADTHTCSDSEEGPERAERLAIPKRIRRSLP
PGLLRRISSTWTTTTSATGLPTLEPGPVRRDRSASIKHTGDRLSISESWNNSVMMTISKS
RSMSASCAVSVTSNHLHGKPPGRRFPSSNESPLGSPCPSPPVQGTPVSSPTVTTCSVQLP
EPPGPLAERSPDPVAHKSHHKALTHSQSAPSSTTPYWRPPSLCGSCGRPFNHRLNRRAES
ADKGDRIPHPDERAVASSDYDSTYDSTYETNHSDSSDFAQNEEEGEGGKKLPEEKPILAA
EPVTLPELEPLLSQLNNWNFPIFSLVEKTQGCILSQVSYKLFEDTGLFETFRIPVQEFMN
YFHALENGYRVIPYHNRTHATDVLHAVWYLTTQPVPGLPTALTENGMNSVDSENGINAGA
TCFLVSKMNSVLEDGYGSLAGLIPGLELMALYVAAAMHDYDHPGRTNAFLVATSAPQALL
YNDRSVLENHHAASAWNLFMSRPEYNFLANLEHVEFKRFRFLVIEAILATDLKKHFDFLA
EFNAKVGEEGVSGIDWTNENDRLLVCQMCIKLADVNGPLKCKELHLQWTEGIVNEFYEQG
DEEATLGLPISPFMDRSAPQLAKLQESFIAHIVGPLCSSYDSAALMPGCCVDLPEGESDP
EEEKDEEKEERDTEQDGMTDEEASTSSNTSQERETKKVSRRKVFCQITQHILENHEMWKR
VIAAEEEAERADPNCIGSPTDPITSIHEEEEEQASKEESVDGLDQSESSGEKEEDP
>Oryzias latipes_PDE3Aa(ENSORLP_5649)
SSRRLASAVCVGTLSVFVAALVKRAEWRAEASSGADGALSQALSPLLLVAGCAAELLQTC
WSAVSLLFTLVCAFFWVGVYFIRCGVLIQTALSLLTLCHLGEVAAWSLLDGTDEHLFSFT
TAAALVLVCLAAGALMVARLNQGISVIVFISVVRTISLLSLQKVRATWRPYVAYLVGVLG
ILLARYADKLLPNQGRHKEGCTPVTGSREEVPVFKRRRRSSSVIASDMAHSQPNSKSHRR
TSLPCIQRDQQMLSRSDWDHKRGSRGSQSSGTTVMVDIAVMGEAHGLITDLLADPSLPPN
TCTSLRAVSNLLTTQLTFQPLHRPRPAPLLNPNDAYTCSDSEEGPEKGEKTSIHKRLRRS
LHPGLLRRISSTWTTTTSATGLPTIEPGPVRRDRSASIKPYHESLTCRKTFNSRKIFDLT
RTEVFPTQRDSQLLQPLNGALKKKKTQTGKLTRMSPLSSLCHSVPVGGQLSSTNTDTSSF
TFTEKLNLVSQMLLAAWTPLTILTVHPSLKPTFVFFPILCCNCGRPYIRLSHGEGSVDKG
DRIPRSASPTEDQVVVSSDYDSAHEANHSDSSDVAHTEEDTESPQRKSKNISNTFKFYNF
FMDKPILAPEPLLMEGLDPLLDQLNSWNFPIFTMMEKTNGKRGQILSQVSYKLFEDTGLF
ETFKIPVKEFMNYFHALESGYRDIPYHNRVHATDVLHAVWYLTTQAVPGLPSLLTDHGSA
SDSDSDSGITHSHMGFLVSKTYTVSEDGYGCLSSLIPALELMALYVAAAMHDYDHPGRTN
AFLVATSAPQAVLYNDRSVLENHHAASAWNLFMSHPEYNFLVNLDHVEFKRFRFLVIEAI
LATDLKKHFDFLAEFNAKVGDDPTNGIDWSNENDRLLVCQMCIKLADINGPLKCKDLHLQ
WTEGIVNEFYEQGDEESSLGLPVSPFMDRKAPQLAKLQESFITHIVGPLCNSYDSAGLIP
GKWVEPNPDEEDTEAAENDEDEEDTVEEDASSSSEVSEKATLKKRRKVFCQITQHLLENH
EMWKKVIEKEEEEAQNAGQGTDSVHLNNVSEPILVIDEEEEESGSKEEQVEGERPEE
>Oryzias latipes_PDE3Ab(ENSORLP_10351)
FQSSGTSVVVDIAVMGEAHGLISDLLADPSLPPNTCSSLKAVSNLLSTQISLQPLHRPRI
PPDTRPCSDSEDGPEKPERLALPKRSENLNSRNSWPSPFTLFKTEEGLVSLLNKLTSSQS
YKGKQTTHSVILSLLGVSPECPGSSLEFPIRKDMASFLYLTFTKPLGRSGGTPVPSPTIK
MCPVQLPEPAGPQTERTPVSVAPKSHHRALTHSQSAPNSTTIHWRPPSLCGSCGRPFNNE
RAVALSDYDSTYDSTYETNHSDSSDFAQNEEDGEGGKKPSVLRESCRECPAEDIVLHPLL
PSPEVANGTSTRTPMMPELEPLMSQLNNWNFPIFSLVERTHGKTGCILSQVSYRLFEDSG
LFETFKIPIKEFMNYFHALENGYRDIPYHNRIHATDVLHAVWYLTTQPVPGLPTLRTENG
IHTATNSANGITPRATSFLASRINLELEEEYGSLAGLIPGLELMALYVAAAMHDYDHPGR
TNAFLVATSAPQALLYNDRSVLENHHAASAWNLFMSQPEYNFLMNLEHVEFKRFRFLVIE
AILATDLKKHFDFLTEFNAKVGDEGVSGIDWTNENDRLLVCQMCIKLADVNGPLKCKELH
LQWTEGIINEFYEQGDEEASLGLPISPFMDRSAPQLAQLQESFITHIVGPLCHSYDNAAL
MPGRWVDLAEGGLEIDMVKEGQGTEEEDTADEDASTGSDTSQQHEAKSKRKVFCQITQHL
LENHEMWKRLIAAETPEETQAEVPICISSPTDPI
>Ciona intestinalis_(ENSCINP_32055)
ESVLLLELAREISDTDDQDKFCFQALRHVVSIVNAEKCSLFWMRDSAKGDSKELASRLWN
ITPKSTFDDVVCDSKNELVVPVGVGIAGLVAETKEAVIVSNVYEHPNFNKTIDEKTGFES
RDLLCQPLVLKREDKVVGVVEVVNKKNKEPFTTEDAQVLEHFLVLCNLAIQNCRGAAQIT
RLQQAATVSFLWQVNILFVGLSYYRIRFHKEVVMQISDLIQCERYTLAIALIDNCNIEGC
LQFAKSYDLLLQKPKASMFDDEDQPIVKTVEVNNIAGYIFIYKKKQQSITNGIADVLRFL
SMHSTLTAANCTKTLLNDICFIFMFEECKLLDDAKKEFSLKSALCVAFYDGTDRLLGVLH
LGNKKKKGFDENDEAVIQSVRPYIMNGLLFANGFNSIVINKAKTDVAEDTVRFHIRPWQD
EVDRVVVSLAVYGNRKWSLIIMDAAFFSQNEPIPEGEKYNLYQFTFSDLLMSDDETVMGA
MRMFLDLDAFNLFHIRQETMLRWLITTRRCYRPVYYHNWRHGLNVAHTMFLLLDRMTPGI
DKAFNDREKFALVVACFCHDIDHRGTNNAFLIRAGAPLAILYNTSTLENHHYDTCLRISS
IDGNNIFESFTKEQFESACELMKHAILATDLALYFQRRNTFKKLLEKPFEERDFVQNNDN
RMLLMSMMMTACDLSSITKPWEVQQKMAKLVTSEFYDQGDQERALFGTEPMPMMDRRKID
DLPKMQIGFIDGVCSMAYEMMADFCPGYAPLRDGMRANRQSWKDLASE
>Ciona intestinalis_(ENSCINP_10920)
EEYIIANVRLETLNRWCTKKRSQLQNDSVAGEGKRILEKETKSIYNNSELLFEKISTGNY
LHPLYMLCSHLQTSTMSTSFTFYAVGGTCDTIHLYNPELPQWQNDPPPESRTSILPSYPV
EEGGTVASHVASTQQSVTIDDITMDERFPKGTSTLESAAVSVMCLPVALPNGDLIGVVEF
CRAWHNAEYTFETLAMAQTTLTWATMAIDKTQVSSGLEQQNAMSNFLLQVSRTYLDDITD
VDNIIQHIMRFAKTLVSADRCALFLHDKEAGELYSNLFDNGEVMDGKSVFSKKTELRFSV
TKGIAGASVRTKQTLNIPDAYSDPRFNRAVDKATGYTTKSILCIPIMSNDEVYGVVEMIN
RKDGGSFTMNDQNNFQMFAVFCALALRYSKVHTRLQKDQCRHAILKEKYFYHSQYSKADY
NELIKAQKDDETFVLPPNFDRFHFSLFHLDKKLMSYFINMVIELAGSGSHLLPSANVMTD
FILTVRENYRDIQYHNWQHAMTVTHAMFCMLKQNLEIFDEVERYALLVACVCHDLDHRAR
SNQFLQKTSHPLALLYPASTMEYHHISMAKDILGRKESKVFQNMTNEEYEKAMYVLKEAI
LATDLALYFGNRGQIEELLTQGEFDFDNQQHRTSAIGLMMTACDLSSSAKDWSVTRQNLL
DLHYEFWEEGDQRKKLGIKPLLPMMDRALEEDLAEGQVGFYSNVSIKCFESLARVLPSCE
PLAIRGKENLGHWRKEAEIVKEKKEEKRKIAEKEKQREERLKQEGLGLTLRGGMWVVEES
RPTS
>Ciona intestinalis_(ENSCINP_11667)
MLLGVRLTKGGSSNQICNESQHYLSNFSHDHIPERHVSQSISHSNNCSKETFNKTKRTPS
TRVLSDAAHRLDAFMPCVVLMKKQASISHKQCLSIGMHPNPRKTKRRASLDVIKEHNVLT
EGLRWRDVMNRRRTSLPAILASSKRKAVMSSTLVDTSTLVEIQSTLEKLGKSPALVESLV
EDLQNLLKPYKTDHVRPRQVVWLHDSGTDGSDDDVVSTPRHSAGKRSASRRNEWNPSKDI
FSTTTTATGLPTEEPAPAKPKRLPKISKEKSPLVSPLDSRCSSPVIDSSIRANLGRRKTY
PSLPSSGSQVYFPSSHNLLSVHKKFPTVSSDYESCDNDDVTSPIARSKSVNEKDSDPLDL
HHLQHHLHHDEEDNEFLTSTSQLDDDITIMEEVVTCRGNQWSDDELTDDGYNFFLHYQQK
LLESVYKWNFPIFTLAQQTDCVLSQMAFKLFQDTGLFETFKIPKQEFVQYMRALEEGYRN
IPYHNRIHAADVLHGCWYLSTQAIPGFHESSALFSSDSSDSDSGTGTSHNHCQVNNIGHG
SLAQAIPALELMSLYLAAAMHDYDHPGRTNAFLVETRHPLAILYNDRSVLENHHASSSWG
LLYSDPRFNFLKNLDTAEWKRLRFLVVEAILATDLKKHGEILSQFSVKSQNGLNWSADAD
RLLVCQMVIKLADIGGPAKERNLHITWTKAICEEFFIQGDEERELGVPVSPFMDRERPQV
AELQRTFINNLIKPIVQSMYKTGILAGKAEDNEADESPMEDQSQCLLLEQLKDNLNFWEV
KTPTSGHEEMNEAFKLALHVDLSMRNSRTNLNIPNHTEPIDDVIITNKTDNDVNNKQQCN
DCVTTNNTTIRNSPSKLGTIPKLQPPKIVINHKVSSHTS
>Ciona intestinalis_(ENSCINP_11667)
MLLGVRLTKGGSSNQICNESQHYLSNFSHDHIPERHVSQSISHSNNCSKETFNKTKRTPS
TRVLSDAAHRLDAFMPCVVLMKKQASISHKQCLSIGMHPNPRKTKRRASLDVIKEHNVLT
EGLRWRDVMNRRRTSLPAILASSKRKAVMSSTLVDTSTLVEIQSTLEKLGKSPALVESLV
EDLQNLLKPYKTDHVRPRQVVWLHDSGTDGSDDDVVSTPRHSAGKRSASRRNEWNPSKDI
FSTTTTATGLPTEEPAPAKPKRLPKISKEKSPLVSPLDSRCSSPVIDSSIRANLGRRKTY
PSLPSSGSQVYFPSSHNLLSVHKKFPTVSSDYESCDNDDVTSPIARSKSVNEKDSDPLDL
HHLQHHLHHDEEDNEFLTSTSQLDDDITIMEEVVTCRGNQWSDDELTDDGYNFFLHYQQK
LLESVYKWNFPIFTLAQQTDCVLSQMAFKLFQDTGLFETFKIPKQEFVQYMRALEEGYRN
IPYHNRIHAADVLHGCWYLSTQAIPGFHESSALFSSDSSDSDSGTGTSHNHCQVNNIGHG
SLAQAIPALELMSLYLAAAMHDYDHPGRTNAFLVETRHPLAILYNDRSVLENHHASSSWG
LLYSDPRFNFLKNLDTAEWKRLRFLVVEAILATDLKKHGEILSQFSVKSQNGLNWSADAD
RLLVCQMVIKLADIGGPAKERNLHITWTKAICEEFFIQGDEERELGVPVSPFMDRERPQV
AELQRTFINNLIKPIVQSMYKTGILAGKAEDNEADESPMEDQSQCLLLEQLKDNLNFWEV
KTPTSGHEEMNEAFKLALHVDLSMRNSRTNLNIPNHTEPIDDVIITNKTDNDVNNKQQCN
DCVTTNNTTIRNSPSKLGTIPKLQPPKIVINHKVSSHTS
>Ciona savignyi_(ENSCSAVP_15022)
MSLYLAAAMHDYDHPGRTNAFLVETRHPLAILYNDRSVLENHHASSSWGLLYSDPRYDFL
KNLDTAEWKRLRFLVVEAILATDLKKHFVILSQFGVKSQNGKGISWSADEDRLLVCQMVI
KLADIGGPAKKRNLHMTWTKAICEEFFIQGDEERELGLPVSPFMDREQPQVAELQRTFIN
NLIKPIVQSMHKSGILAGKVEESEESEVVESNESLLLEQLKDNLNFWKAKQPACGHEEMN
EAFKLALPVDLSIRETNPAFSTQRVNVTITDNPICRVNKPDNLSSTEGITSSQHIVSSKP
>Ciona savignyi_(ENSCSAVP_15022)
MSLYLAAAMHDYDHPGRTNAFLVETRHPLAILYNDRSVLENHHASSSWGLLYSDPRYDFL
KNLDTAEWKRLRFLVVEAILATDLKKHFVILSQFGVKSQNGKGISWSADEDRLLVCQMVI
KLADIGGPAKKRNLHMTWTKAICEEFFIQGDEERELGLPVSPFMDREQPQVAELQRTFIN
NLIKPIVQSMHKSGILAGKVEESEESEVVESNESLLLEQLKDNLNFWKAKQPACGHEEMN
EAFKLALPVDLSIRETNPAFSTQRVNVTITDNPICRVNKPDNLSSTEGITSSQHIVSSKP
>Ciona savignyi_(ENSCSAVP_9294)
MATEAQLNRELVEAWLDDHAEFAFDYFTRKATQTMVNTWLADRVIRIAGSDRKISSIERS
PTKHDNDPTIRPPSTSGDSTGRKTPIRKISHEEIKPGHLPLKPMVLTDEMGSPSFYTPDS
ATSPSLTRRMNNQRDMIMDLVIDIASDLDVTSVSHRILQNVSILVDADRCSLFLMRERDG
EKFLVSRLFNVSKESTLEDNVVVKDEIKMKLGQGIAGMVALTGTTLNIPDAYKDHRFNQS
VDKKTGYRTRSILCMPIRDGDKRIVGVAQVINKTEGAFTSKDEKIFASYLGFCGVAIHNA
QIFEKVQLENRRNEILLDLARVLFEEQSSLSTVMDTILTHTVSLLSCERASVLLANPSQP
ENVFEHTFEHVDESTITSNLNFDKNSPQRNKVPLNIAITSYVRQTGQIVNIENASSDQRF
EFLEDTELGFTTRSLLCIPIWDSFRQVIGVIQLINKHHRVGPRFTKSDEQILEAFAIFCG
LGISNTRMYEETARLAAKQQVILEVLSYHAVASPLETNALLTNDIPSSKSLGILKYEFDD
TTLSDLDTVRASVRMFIDLKLVEKFRINHETLCRWVASVKRNYRPVSYHNWRHAFNVCQS
CFCMVKTGGLDTVFSDFEKLALLVSCLSHDLDHRGTNNAFQAKIEHPLARLYSTSTMEHH
HYNQCLMLLQSDGCEILSHLSSTEYAQVIKLIQHAILSTDLAIYFKKRGEFFNILRSENA
DWKGNDSHRELLRSLVITGCDIAGITRPWKVQKEIAQLVAEEFFEQGDIEKTKLHQEPPD
MMNRKLKHKLPKMQIGFIDSICLPLYEALSDVEPGLQPLLNGCLDNRRHWE
>Ciona savignyi_(ENSCSAVP_900)
YQYKVGLVYFQPKSHNPFIFMKITDGNYLYPLYLLCGQLQIATLSTGFTLYAVGGSGDTI
HLYNPELPEWKDNPPPQNRYQIGKHGTVASHVAVTRQPVVVHDVNMDDRFPKGTSSQDSD
ALSVLCMPIALPNGDLLGVVEFIRTWHKAGYTLDTVEMAQTFFTWATMAIHKTQVSCGLE
KQSAMSNFLLEVSRTYLDDLTDVDNIIQHIMRFAKSLVSADRCAFFLHDMEREELYSNLF
DAGEVIDGQTVFSKDTEIRFHVSKGIAGAAVTTKQILNIPDAYSDPRFNREVDKATGYTT
RSVLCIPIMGGDEVHGVVEMINRRGGGAFTMTDQNNFQMFAVFCALALRYSKVHTRLQND
QSRYMILKEQYCYQSRYSNEDYENLTLLQQDEDNFVLPPNFDRFYFSLFHLDKELMGYFI
KMVHNSADTCSLLPPADVLTQFTLTVRANYRNIHYHNWQHAMTVSHSMYCMLKDNVEIFD
EVERYALLVACLCHDLDHRALSNQFLQKTSHPLAQLYPTSTMEYHHINMMDIIGRKDCTV
FEKLNSTEYERAVYVMKEAILATDLALYFGNRGQIEELLTQGDFDFDNQQHRTSAIGLMM
TACDLSSSAKDWEVTRNNLLDLHFEFWDEGDQRKRLGIEPLLPMMDRDLEEDLAEGQVGF
YSNVSIKCFESLARVLPSCEALAANGKENLERWRQ
>Caenorhabditis elegans_(R08D7)
MLELRRNSSPSSAHPSPQTNCQNSQRGDGLHHHHHEAASGSTCCGGMTVFTGANAAKSSN
EPAGSASPTVWRKTSHPPLHFNNNETRNRNLQMQLKNRGTKDDWGASLRYDIEEPTSSGL
LELLPDVPIVRKLSRPLVKMDDQDDACSVASNESDRTVLSPLVPMSIFDQFLCLTNNLSA
LISCIIAEAKKNTEAEDYAVFLHDEDNKQMVLFNNETMLMTGKKFDMGYGIVGKVASTMR
TMNIRDVSRCPFFNEEIDEQFSIKARNLIAFPLIDSSCSLIGVIVLYNKENGFSRHDEKY
IKRFSYFVANSIAHAILAKQIEEVRTRIHMVEEFKIQGEDAVIEEVDIMRLVNDPLRDWR
YFSQNFADFSFPPRSVGENHFHRASMMFFEDLGFSMLYKLNKRKLSYLVLRVSAGYRPVP
YHNWSHAFAVTHFCWLTLRTDAIRRALSDMERLSLLIACLCHDIDHRGTTNSFQMQSLQK
TPLSVLYSTEGSVLERHHFAQTIKLLQQEECSILENLPAADFRTIVNTIREVILATDISA
HLRKQERIKTMISEGYNPMSFDHRYLLMCLVMTASDLSDQAKNFHNAKRIAENIYLEFFA
QGDLELQLGVKPLEMMDRTNAYVPTVQIDFLFKIGVPVFQLLASVVPEGRTTSEAIDANH
LCWVALDEEVRNNPSATNTLEYLRDENLERRIYDRVRKQDPRAAEIASKRFEPVYANGSV
PQTQDILDHRFDGYDKKYQIGCSGGQNQSNGKQQQIRSLQKIRSKTSEDDALLKPMDNGG
SVAASSTRRGSRTPRRLWRRARQLISSMSSSCASCSPLPSRRQVSEDSESC
>Caenorhabditis elegans_(E01F3)
MSPGPPAVGGVSPPVMVPGSAPPFQPTHQYFQHHYHQTPPGKLRDRSPRLSAEMRKNRDT
ATSSPASSGVSIQQRRGSTTQNSGVGSIGLPVLGGRGRGVMSDGHMQRTFHEAMRQRRTS
LPANSLSLNGAKVTGSSLSEAKGLIADMLMNKELPGNVASCLRAVTMLLEQRPLPLNGLL
NDFGLPSVVENPYGGESMVVGASKPRISNITFSTVTSATGLPTVPAEPNKARSSSYWKTE
ASPSNNNEHETPVDLLRKISVSRKESGTHVDTVVTTIDGQRYDTRELDTDPDLAETAVWS
FPIFQMSRKHPQTILSRLTYNIFQQAELFRIFKVSPIKFFNFFHALEKGYWEIPYHNRIH
AADVLHGCYYLSAHPVRSTFLTPKTPDSVLTPPHPHHQHSSIMSQLSTLELMALFTAAAM
HDYDHPGRTNAFLVQVEDKKAILYNDRSVLENHHAAESWKLLNKPENHFIENLDPAEMKR
FRYLVLEYILATDLKQHFEIIMTFTERLTEIDVQVETDRLLIGKLLIKMADINSPTKPYG
LHRQWTDRICEEFYEQGDDERRRGLPITPYMDRGDAQVAKLQDSFIAHVVSPLATAMNEC
GLLPILPGLDTSELIINMEHNHRKWKEQIELENGGSYEAQITCNGGTAVNGVIEEESAST
SDSPDPRRDSPLDSDLSQVPFTICCSIAEEEYV
>Caenorhabditis elegans_(C32E12)
MDDASVLKYLQENPKLVEDFVVSNEISPETFKRWAVRRTMKYKNVKNGTSGGTGAWTEPD
LSMKRRVILETSDNRTRILYEITQCCGQLIGTNSIELIVQNDEGAFSCRKTENGELKLKK
VKTSKSADYIQTIVNAGNQTIAEIHFYTQLDSTEKSIVNAVCTWAAATNYYSELYTHKQE
GSDGQDIHENIAKQRKLSNFLLDVARSIFHDIVSMDAVIIKVMNFAQKLVDADRASLFLV
DSKNAQIYARIFDVGTGDEEHVRVNSEGQKEIRFDMSKGIAGYVASTGEGLNIENAYEDE
RFNADVDSKTGYTTKTILCMPILIRGIVIGVVQMVNKHDGVFTRQDEDAFEIFAVYCGLA
LHHAKLYDKIRRSEQKYRVALEVLAYHSVCNADEVNKLKKIEINNRIVELETIDFNGMRL
SELEKPLYAVYMFKTLFADTLRFDTEDLIRFVLTVRKNYRRVAYHNWAHGWSVAHAMFAT
LMNSPDAFTKLEALALYVSCLCHDLDHRGKNNAYMKTMSTPLASIYSTSVMERHHFNQTV
TILQQDGHNILKSLSSEDYKKTLSLIKHCILATDLALFFSNKAKLNVILDNNTFDINRQE
HRLLTQAVMMTGCDLVASAKPWNIQTETVKVIFEEFYDQGDAERLSGKEPIPMMDRQQAH
MLPQMQVGFMRGICMPCYDLIARIFPKNDKMRERCEYNAKKWEELAEEQRKKQEALAQQN
GEANETQE
>Caenorhabditis elegans_(E01F3)
MSPGPPAVGGVSPPVMVPGSAPPFQPTHQYFQHHYHQTPPGKLRDRSPRLSAEMRKNRDT
ATSSPASSGVSIQQRRGSTTQNSGVGSIGLPVLGGRGRGVMSDGHMQRTFHEAMRQRRTS
LPANSLSLNGAKVTGSSLSEAKGLIADMLMNKELPGNVASCLRAVTMLLEQRPLPLNGLL
NDFGLPSVVENPYGGESMVVGASKPRISNITFSTVTSATGLPTVPAEPNKARSSSYWKTE
ASPSNNNEHETPVDLLRKISVSRKESGTHVDTVVTTIDGQRYDTRELDTDPDLAETAVWS
FPIFQMSRKHPQTILSRLTYNIFQQAELFRIFKVSPIKFFNFFHALEKGYWEIPYHNRIH
AADVLHGCYYLSAHPVRSTFLTPKTPDSVLTPPHPHHQHSSIMSQLSTLELMALFTAAAM
HDYDHPGRTNAFLVQVEDKKAILYNDRSVLENHHAAESWKLLNKPENHFIENLDPAEMKR
FRYLVLEYILATDLKQHFEIIMTFTERLTEIDVQVETDRLLIGKLLIKMADINSPTKPYG
LHRQWTDRICEEFYEQGDDERRRGLPITPYMDRGDAQVAKLQDSFIAHVVSPLATAMNEC
GLLPILPGLDTSELIINMEHNHRKWKEQIELENGGSYEAQITCNGGTAVNGVIEEESAST
SDSPDPRRDSPLDSDLSQVPFTICCSIAEEEYV
>Nematostella vectensis_(XP_001636689)
MCHRKTSSSVRIQQGTTIAAYVAYTLKPVRTTDILGDERFPQGTGVDSKCTTAQSILCQPIVQSNGELVG
TIELSRMVGRDPFDEEDEEVFNSYLVWGGISLYYAEMYLHMHKHRKLTEFLLNVTRSIFQDIVSMDTVIM
KIMNYAQTLVDADRTSLFLVDNKTNELYARIFDIGGSLEDSRSSQLQKEIRFPKTKGVAGYVATSGETLN
ISDAYHDDRFNREIDIQTGYTTRTLLCMPIFIRGNIIGVVQMVNKKSGVLIMCFSSDEKSFQTFAIYCGL
ALHHAKLYDKIRRSEQKHRVALEVLSYHSKCSEGELHRLKELDCPDPYPDLETYEFDSYSLDSEVMPKLV
IFQTRNLFSLSRFDLDELYRFVLTVRKNYRKVPYHNWTHAFAVAHCMYLVIRSGHNNFTGLEALAMFFAC
LCHDLDHRGRTNSWMKNEGTPLAAVYSTSTMEHHHFNQTITILQHEGHNIFSQLNSAEYKTVLGYMKECI
LATDLALFFGNKAKLKDVVDKGTFSWDDQEHRRLLRAICMTACDLSACTKPWRIQYKIVEVIYQEFYAEG
DLEKAQGKQPIPMKDRNTAHELPAHQVGFLVGICLPCYELLGKVIPGTKPLVDGGK
>Nematostella vectensis_(XP_001635720)
MGLNKESKLDLKNSNEREFFFEIVRDIANDLDLKTLSYKILVNVGILTNADRCSLFLVEGPKGKQWLVSK
VFDVHIGSLNVSSAKEAIDHQREIRVPLGVGLVGYAAETGETVNIPDAYADPRFNQDVDKQTGYHTKSLL
CKPVKNNEGEVVGVAQIINKNPGGVPFTKEDEKVCDMYLTFCGIGITNAKLFELSAIEFNRNRALLELVH
DIFEEQTSLEKVVHKIMKRALGLLKCEKCSVLLLTQPELRFSRVFNLKTTGRITSNTRYGFILLLVSEGH
NDRSFTSRVAKLVAATGKTMNIPDASQDTRLADSSNVEKKGFSPILCMPIRNNKFEIIGVAELINRLDNK
PFDENDETLFEAFAIFCGLGIHNTMIYDQMARAKAKQQVALEVLSYHVAAKKTEVEKIRDTQVPKAVDIN
LHSFKFDDFSLAADDMLIASLRMFKDCGFIEEFHIDYEVLSRWILTVKNNYRNVIYHNWRHAFNVAQSMF
CMLTTGGMASVITKLECLGLIVGCLCHDLDHRGTNNAFQAKTDSPLSKLYGTSTLEHHHFNHAVIILSTE
GFSPILSDEYRQVISYIKHSILSTDLATNFKQRPKFFALVESGEFDPYNMDHRDMLKAMMMTACDLNGTT
KPWEIQKEVVNLVTREFFEQGDMERERYNMEPMAIMDRQKIDELPKLQVQFFETTGLPVFKVLAKLNNKL
QPLVDGAESNKRRWQKLDAERGLAS
>Nematostella vectensis_(XP_001631585)
MINLEDASTEQKVESWLDEHPEFVQSYFARKANRSLVDSWLHSRSHARTPSGTPPPSGSSTPVRKISASE
FEGRGILKPLVNVVDGQLSFLSPSEPSRKRSTAHRNRKSRLELQQLDEKEVLMELVKDISNDLDVQSLCH
KILQNVSILLNADRCSLFLCQGPKEGPRFLVSKVFDVNAESKLEDVQCLEEIRIPWGTGIVGYVAETGET
VNIPNAYEDARFNKEIDKKTGYTTRSILCMPIKDHDGEVIGVAQVINKTGKSTDSAFTIDDEQIFLKYLV
FCGIGINNAELYERAQLEIRRNQVLLDLARTIFEEQTSLHNIVHKIMMITQSLLQCERCSVLLVDPTSKT
LFAQAFDLEAKDYLQNDDDDKTVEVRFPINIGITGHVATTGETLNIPDAYADERFDPTVDQVSGFTTKTI
LCMPIKNASGDIIGVVQLLNKVDGTPFNKNDENLFEAFAIFCGMAIHSTVMYENVNKAMAKRKVALEVLS
YHAVSPLEEAIKLKEEPLPPITSLRLIDFAFDDMSISDDDTLKGCLAMLCDLKIVETFQIDYLTLCRFVL
TIKKNYRPVMYHNWRHAFNVAQTMYAMLKKPSIGKYFTVIEQYALIVACLSHDLDHRGTNNSFQIKSATP
LAQLYSTSTMEHHHFDQCIMIINSQGNEIFNTLSADEYNKIIKLLEASIIATDLALYFQRRGDFFKKVEN
RELDWSDDSSKDLLRAMMMTACDLSAITKPWLVQKRTAHLVAEEFFQQGDLEQEELHSTPLPTMDRRKKD
ELPQMQVGFIDAVCLPLYKAFSQFDDNLKVLKDGCRENRRQWQKLAEDHKAREVSCRTRV