>Homo sapiens_MAPK8(ENSP_363304)
MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEAAA
GPLGCCR

>Mus musculus_MAPK8(ENSMUSP_22504)
MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAMINGSQHPSSSPSVNDMSSMSTDPTLASDTDSSLEASA
GPLGCCR

>Rattus norvegicus_MAPK8(ENSRNOP_60904)
MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFERLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAVISGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEAPA
GPLGCCR

>Anolis carolinensis_MAPK8(ENSACAP_11352)
MSRSKHENNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKLLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPVDSEHNKFKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYNEV
IELEEKTKNGIIRGQPSPLGAAMINSSQPQSSSSSVNDAASMSTDPTLISDIDSSLETSA
GPLGCCR

>Danio rerio_MAPK8(ENSDARP_119001)
MNKNKREKEFYSVDVGDSTFTVLKRYQNLRPIGSGAQGIVCSAYDNNLERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ
MELDHERLSYLLYQMLCGIKHLHAAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAATGL
LMTPYVVTRYYRAPEVILGMGYQANVDIWSVGCILAEMVRHKILFPGRDYIDQWNKVIEQ
LGTPTQEFLLKLNQSVRTYVENRPRYTGYSFEKLFPDVLFPADSEHSKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPAEVEAPSPLITDKQLDEREHTVEEWKELIYKEV
LDWEERMKNGVIRGQPSPLGAAVINGSPQPSSSSSINDVSSMSTEPTVASDTDSSLEASA
GPLSCCR

>Takifugu rubripes_MAPK8(ENSTRUP_43883)
FTMNRNKREKEYYSIDVGDSTFTVLKRYQNLRPIGSGAQGIVCSAYDHNLERNVAIKKLS
RPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKTLEEFQDVYLVMELMDANLCQV
IQMELDHERLSYLLYQMLCGIKHLHAAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAAT
GLLMTPYVVTRYYRAPEVILGMGYQANGFTHVVDIWAVGCIMAEMVRHKILFPGRDYIDQ
WNKVIEQLGTPSQEFLMKLNQSVRTYVENRPRYAGYTFEKLFPDVLFHADSEHNKLKASQ
ARDLLSKMLVIDASKRISVDEALQHPYINVWYDPTEVEAPPPAITDKQLDEREHTVEEWK
ELIYKEVLDWEERTKNGVIKGQPASIGAAVSSSPQHHGSTSSSTNDVSSMSTEPTLTDTD
SSLEATAANASLGSCR

>Oryzias latipes_MAPK8(ENSORLP_11148)
CALRVLVRQQQADGDVGIAFCERTFLEVQKSAIEELTMNKNKKDKEFYSVDVGDSTFTVL
KRYQNLRPIGSGAQGIVCSAYDQTLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKYVNHK
NIIGLLNVFSPQKSLEEFQDVYLVMELMDANLCQVIQMELDHERLSYLLYQMLCGIKHLH
SAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAATGLLMTPYVVTRYYRAPEVILGMGYQ
ANVDIWSVGCILAEMVRHKILFPGRDYIDQWNKVIEQLGTPSQDFLMKLNQSVRTYVENR
PRYAGYTFEKLFPDVLFPADSDHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINV
WYDPAEVEAPPPKIPDKHLDEREHTVEEWKDLIYKEVTEWEEWTKNGVIKGQPPPLGDTG
AAVIDSPPQPTSSASSSTNDVSSMSTEPSDPSSDPTMASETDSSLNGHTSLSMLACCR

>Homo sapiens_MAPK9(ENSP_394560)
MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP
FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQ
LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK
MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV
MDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPL
EGCR

>Mus musculus_MAPK9(ENSMUSP_136977)
MSDSKSDGQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP
FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQ
LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK
MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV
MDWEERSKNGVKDQPSDAAVSSKATPSQSSSINDISSMSTEHTLASDTDSSLDASTGPLE
GCR

>Gallus gallus_MAPK9(ENSGALP_22313)
MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP
FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKSLEEFQDVYLVMELMDANLCQVIH
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQ
LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESDRDKLKTSQARDLLSK
MLVVDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV
MDWEERSKNGVVKDQPSAQMQQ

>Anolis carolinensis_MAPK9(ENSACAP_16450)
MSESKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP
FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKSLEEFQDVYLVMELMDANLCQVIH
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQ
LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSDSDRDKLKTSQARDLLSK
MLVVDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV
MDWEERNKNGLVKEQPSDAAVNSNTSPSQSSSINDISSMSTEQTLASDTDSSLDALTGTL
EGCR

>Danio rerio_MAPK9(ENSDARP_128194)
AMTEGEGQFYSVQVGDSTFTVLRRYQQLRAIGSGAQGIVCSALDTVLGVPVAVKKLSRPF
QNQTHAKRAYRELVLLKCVNHKNIIHLLNVFTPQKSLEEFQDLYLVMELMDASLCQVIHM
DLDHERMSYLLYQILCGIRHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFM
MTPYVVTRYYRAPEVILGMKYKENVDIWSVGCIMGEMVKGSVIFQGTDHIDQWNKVIEIL
GTPSLEFMNRLMETVRNYVMNKPQFPGVSFNELFPDWAFPSETEHDKIKTSQARDLLSKM
LVIDPECRISVQEALNHPYIHVWYDPAEADAPPPQISDKQLEEREHSIEQWKELIYKEVM
DWEERNKNGVLKEECLDGTVNSSATPSQSSSINDISSMSTEQTLASDTDSSCIDTLTGPL
EDCR

>Takifugu rubripes_MAPK9(ENSTRUP_615)
MSEEEGHFYSVQVGDSTFTVLKRYQQLRAIGSGAQGIVCSALDTVLGIPVAVKKLCRPFQ
NQTHAKRAYRELVLLKCVNHKNIIRLINVFTPQKSLEEFQDLYLVMELMDANLCQVIHMD
LDHERMSYLLYQILCGIRHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMM
TPYVVTRYYRAPEVILGMKYKENVDIWSVGCIMGEMVKGSVIFQGTDHIDQWNKVIEVLG
TPNLEFMNRLMETVRNYVMNKPQYPGVSFTELFPDWAFPSDSEHDKLKTTASQARDLLSK
MLVIDPECRISVEEALNHPYIHVWYDPAEADAPPPQISDKQLEEREHTIEQWKELIYEEV
IDWEERNKNGLITGNPENPSATTRR

>Oryzias latipes_MAPK9(ENSORLP_6510)
MSEAEGQFYSVQVGDSTFTVLKRYQQLRPIGSGAQGIVCSALDTVFGIPVAVKKLCRPFQ
NQTHAKRAYRELVLLKCVNHKNIIRLINVFTPQKSLEEFQDLYLVMELMDASLCQVIHMD
LDHERMSYLLYQILCGIRHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMM
TPYVVTRYYRAPEVILGMKYKENVDIWSVGCIMGEMVKGSVIFQGTDHIDQWNKVIEILG
TPSLEFMNRLMETVRNYVMNKPQYPGVSFGELFPDWAFPSESEHDKVKTAQARDLLSKML
VIDPECRISVEDALNHPYIHMWYDPSEADAPPPQISDKQLEEREHTIEQWKELIYEEVID
WEERNKNGLMKEDCSEWQE

>Homo sapiens_MAPK10(ENSP_378598)
MSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQ
LGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSK
MLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEV
MNSEEKTKNGVVKGQPSPSGAAVNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAG
PLGCCR

>Mus musculus_MAPK10(ENSMUSP_108468)
MGDTGVSGAPMKEMAQVMRIAEVTEDGRVFMSLHFLYYCSEPTLDVKIAFCQGFDKHVDV
SSIAKHYNMSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNV
AIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMD
ANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGL
ARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYID
QWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKAS
QARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHTIEEW
KELIYKEVMNSEEKTKNGVVKGQPSPSGAAVNSSESLPPSSSVNDISSMSTDQTLASDTD
SSLEASAGPLGCCR

>Xenopus tropicalis_MAPK10(ENSXETP_13630)
MSRHFLYNCSEPTLDVKIAFCQGFGNQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKSLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDEALQHPYIN
VWYDPSEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNFEEKTKNGVVKGQPSPSGAA
VNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR

>Danio rerio_MAPK10(ENSDARP_114143)
MSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAGYDAVLDRNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKSLEEFQDVYLVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQ
LGTPSPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDCLFPADSEHNKLKASQARDLLSK
MLIIDPAKRISVDEALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHSIDEWKELIYKEV
MNFEERTKNGVVKGQPSPSGDVQN

>Takifugu rubripes_MAPK10(ENSTRUP_33127)
MSRHFLYNCSQPILDVKIAFCQGFGQQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAGYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKSLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPSPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDCLFPADSEHNKLKASQARDLLSKMLIIDPAKRISVDEALQHPYIN
VWYDPAEVEAPPPQIYDKQLDEREHSIDEWKELIYKEVMNFEERTKNGVVKGQPSPSGAA
VNSSESPPPSSSINDISSMSTDQTLASDTDSSLETSAGPLGCCR

>Tetraodon nigroviridis_MAPK10(ENSTNIP_5893)
MSRHFLYNCSQPILDVKIAFCQGFGQQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAGYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKSLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPSPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDCLFPADSEHNKLKASQARDLLSKMLIIDPAKRISVDEALQHPYIN
VWYDPAEVEAPPPQIYDKQLDEREHSIDEWKELIYKEVMNFEERTKNGVVKGQPSPSGAA
VNSSESLPPSSSINDISSMSTDQTLASDTDSSLETSAGPLGCCR

>Gasterosteus aculeatus_MAPK10(ENSGACP_21655)
MSRHFLYNCSQPILDVKIAFCQGFGKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAGYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKSLEDFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDLWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPSPDFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDCLFPADSEHNKLKATASQARDLLSKMLIIDPAKRISVDDALQHPY
INVWYDPAEVEAPPPQIYDKQLDEREHSIDEWKELIYKEVMNFEERTKNGVVKGQPSPSG
AAVNSSDSLAHSTYINDISSMSTDQTLASDTDSSLETSAGPLGCCR

>Oryzias latipes_MAPK10(ENSORLP_7884)
MSRHFLYNCSQPVLDVKIAFCQGFGKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAGYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKSLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPSPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDCLFPADSEHNKLKAXQARDLLSKMLIIDPAKRISVDEALQHPYIN
VWYDPAEVEAPPPQIYDKQLDEREHSIEEWKELIYKEVMNFEERTKNGVVKGQPSPSGAA
VNSSESLPPSSSINDISSMSTDQTLASDTDSSLETSAGPLGCCR

>Homo sapiens_MAPK11(ENSP_333685)
MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVG
TPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAA
EALAHAYFSQYHDPEDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPGSL
EIEQ

>Mus musculus_MAPK11(ENSMUSP_86204)
MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGNDYIDQLKRIMEVVG
TPSPEVLAKISSEHARTYIQSLPPMPQKDLSSVFHGANPLAIDLLGRMLVLDSDQRVSAA
EALAHAYFSQYHDPDDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPLEPSQLPGTH
EIEQ

>Anolis carolinensis_MAPK11(ENSACAP_1802)
MSERGGFYKQELNKTVWEVPLRYQQLTPVGSGAYGSVCSACDTKTRQKVAVKKLSRPFQS
LIHARRTYRELRLLKHMKHENVIGLLDVFTPATSIENFNEVYLVTNLMGADLNNIVKCQK
LTDDHIQFLIYQLLRGLKYIHSAGIIHRDLKPSNLAVNEDCELRILDFGLARQTDDEMTG
YVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLKGKALFPGNDYIDQLKRIMEVVGT
PSSELLKKISSEHARKYIESLPHMPQQDLKAVFRGANPLAVDLLEKMLILDSDKRITASE
ALAHAYFVQYHDPDDEPEAELYDESIENKERVIDEWKELTYGEVISFKPPDLKMDSLEIE
Q

>Xenopus tropicalis_MAPK11(ENSXETP_48165)
MSGRVGFYKQELNKTVWEVPDRYQRLTPVGSGAFGSVCSAYDTKTRQKVAVKKLSRPFQS
LVHARRTYRELRLLKHMKHENVIGLLDVFTPSTSGENFNEVYLVTNLMGADLNNIVKCQK
LTDDHIQFLIYQLLRGLKYIHSAGIIHRDLKPSNLAVNEDCELRILDFGLARQADDEMTG
YVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLKGKALFPGNDYIDQLKRIMEVVGT
PNSEFLLKISSEHARRYIESLPYMPQQDLKEVFHGANPLAIDLLEKMLILDSDKRITATE
ALAHPYFVQYHDPDDEPEAEPYDESTENKERTIDEWKEITYEEVISFKSQDVKIDNLEIE
Q

>Danio rerio_MAPK11(ENSDARP_34350)
MATRPGFYRQELNKTVWEVPERYQNLTPVGSGAYGSVCSAYDVRLRQKVAVKKLSRPFQS
LIHSRRTYRELRLLKHMKHENVIGLLDVFTPAASLEEFNEVYLVTNLMGADLNNIVKFQR
LSDEHVQFLIYQLLRGLKYIHSAGLIHRDLKPSNVAVNEDCELRILDFGLARQTDDEMTG
YVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMGELLKGKVLFPGNDYIDQLKRIMEVVGT
PTPDVLKKISSEHAQKYIQSLPHMPQQDLGKIFRGANPLAVDLLKKMLVLDCDGRISASE
ALCHPYFSQYHDPEDEPEAPPYDQTPESKDRTMEEWKELVFEEVSNFKDPPNKPESLQVE
Q

>Takifugu rubripes_MAPK11(ENSTRUP_21951)
SSPSVCCRTMSARSGFYRQELNKTVWEVPERYQNLTPVGSGAYGSVCSAYDVVLRQKVAV
KKLSRPFQSLIHCRRSYRELRLLKHMKHENVIGLLDVFTPAAALEDFSELYLVTNLMGAD
LNNIVKFQKLSDEHVQFLIYQLLRGLKYIHSAGLVHRDLKPSNVAVNEDCELRILDFGLA
RQTDDEMTGYVATRWYRAPEIMLNWMHYNQNVDIWSVGCIMGELLKGKVLFPGTDYIDQL
KRIMEVVGTPTAELLKKICSEHAQKYIQSLPSMPPQDMEKIFRGANPLAVDLLKRMLILD
CDGRISASEALAHPYFSQYHDPDDEPEAPPYDQSLESKDRTLEEWKELIFKELSSFKVSG
SKSDSLPVEQ

>Tetraodon nigroviridis_MAPK11(ENSTNIP_9703)
GVCLSFFFFFCVGSRNMSARPGFYRQELNKTVWEVPERYQNLTPVGSGAYGSVCSAYDVV
LRQKVAVKKLSRPFQSLIHCRRSYRELRLLKHMKHENVIGLLDVFTPAAALEDFSELYLV
TNLMGADLNNIVKFQKLSDEHVQFLVYQLLRGLKYIHSAGLVHRDLKPSNVAVNEDCELR
ILDFGLARQTDDEMTGYVATRWYRAPEIMLNWMHYNQNVDIWSVGCIMGELLKGKVLFPG
TDYIDQLKRIMEVVGTPTPDLLKKICSEHAQKYIQSLPFMPPQDLEKIFRGANPLAVDLL
KRMLVLDCDGRISASEALAHPYFSQYHDPEDEPDAPPYDQTLESKDRTLEEWKELIFKEV
NSFKVSSGKTDSLQTEQ

>Gasterosteus aculeatus_MAPK11(ENSGACP_25263)
MSARPGFYRQELNKTVWEVPERYQNLTPVGSGAYGTLCISAYDVVLRQKVAVKKLSRPFQ
SLIHSRRSYRELRLLRHMKHENVIGLLDVFTPAAALEDFKELYLVTNLMGADLNNIVKFQ
RLSDEHVQFLIYQLLRGLKYIHSAGLIHRDLKPSNVAVNEDCELRILDFGLARQTDDEMT
GYVATRWYRAPEIMLNWMHYNQNVDIWSVGCIMGELLKGKVLFPGTDYIDQLKRIMEVVG
TPTPDLLKKICSEHAQKYIQSLPFMPQQDLEKIFRGANPLAVHLLKRMLVLDCDGRISAN
EALSHPYFSQYHDPDDEPVAPPYDQTLESKDRTLEEWKVELVFEEVNCVKTSGNKTDSLQ
AEQ

>Homo sapiens_MAPK12(ENSP_215659)
MSSPPPARSGFYRQEVTKTAWEVRAVYRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM
KHEKLGEDRIQFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMK
VTGTPPAEFVQRLQSDEAKNYMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRV
TAGEALAHPYFESLHDTEDEPQVQKYDDSFDDVDRTLDEWKRVTYKEVLSFKPPRQLGAR
VSKETPL

>Mus musculus_MAPK12(ENSMUSP_86207)
MSSPPPARKGFYRQEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAVDSRTGNKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDESLDDFTDFYLVMPFMGTDLGKLM
KHETLSEDRIQFLVYQMLKGLKYIHAAGVIHRDLKPGNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKILFKGNDHLDQLKEIMK
ITGTPPPEFVQKLQSAEAKNYMEGLPELEKKDFASVLTNASPQAVNLLERMLVLDAEQRV
TAAEALTHPYFESLRDTEDEPKAQKYDDSFDDVDRTLEEWKRVTYKEVLSFKPPRQLGAR
VPKETAL

>Gallus gallus_MAPK12(ENSGALP_14011)
MSSPKNGFYQQEITKTLWEVRDRYRDLQPVGSGAYGTVCSAVDGRSGAKVAIKKLYRPFQ
SQILAKRAYRELRLLKHMKHENVIGILDVFTPDVTLEKFNGFYLVMPFMGTDLSKIMKHE
KLTEDRIQFLVYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHTDSEMT
GYVVTRWYRAPEVILNWMHYTQTVDIWSVGCIMAEMITGRPLFRGNDHLDQLTEIMKITG
TPSQDFVQKLKSQDAKNYIKSLPKVQKKDFASVLKHASPLAVNLLENMLVLDAEERVTAA
EALMHPYFEPIHDPEEEIEAEKYDDTFDNMDLPLDEWKRITYKEILNFKPPQTSESKETA
SMDLQ

>Anolis carolinensis_MAPK12(ENSACAP_1910)
MSSPKKGFYRQEIAKTVWEVRERYRELQAVGSGAYGAVCSATDRKSGTKVAIKKLYRPFQ
SDLFAKRAYRELRLLKHMKHENVIGLLDVFTPDASLDKFNDFYIVMPFMGTDLSKIMKHE
KLTEDRIQFLVYQMLKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHTDSEMT
GYVVTRWYRAPEVILNWMHYTQTVDIWSVGCIMAEMITGRPLFKGNDHLDQLTEIMKVTG
TPTQDFVQKLQSQDAKNYIKSLPKVQKKDFAAILKYATPLAVNLLEKMLVLDAEKRISAA
EALAHPYFEAIHDPEEETEAEKYDETFDNMDLPLDEWKCITYKEVINFNPPPSPESKETA
V

>Xenopus tropicalis_MAPK12(ENSXETP_48167)
MSTSPLPKKGYYRQDVNKTVWEVKERYRDLVAVGSGAYGTVCSSLDTRTGTKVAIKKLYR
PFQSELFAKRAYRELRLLKHMQHENVIGLLDVFTPDSTLENFNDFYLVMPFMGTDLGKIM
KHEKLSEDRIQFLVYQILRGLKYIHSAGIIHRDLKPGNLAVNEDCELKILDFGLARHTDS
EMTGYVVTRWYRAPEVILNWMHYTQTVDIWSVGCIMAEMYTGRPLFKGNDHKDLDQLTEI
MKITGTPTQDFVQKLQSPDAKNYIKSLPKVQKKDFGSLLRYANPLAVNILEKMLVLDAEK
RITATEALAHPYFEQFHDIDDETEAEPYDDSFDNVNLPLEEWRRLTHKELTSYKPLVADS
KETSV

>Danio rerio_MAPK12a(ENSDARP_11298)
MTARSRPGYFRQEINKTIWEVPDRYKDLKQVGTGAYGTVCYALDRRTGAKVAIKKLHRPF
QSDLFAKRAYRELRLLKHMKHDNVIGLVDVFTADLSLDRFHDFYLVMPFMGTDLGKLMKM
ERLSEERVQYLVYQMLKGLKYIHAAGIIHRDLKPGNLAINEECELKILDFGLARQTDSEM
TGYVVTRWYRAPEVILSWMHYTQTVDIWSVGCIMAEMLLGKPLFKGHDHLDQLMEIMKVT
GTPSKEFTAKLQSEDARNYVTKLPRFRKKDLRILLPNVNPQAIKVLDGMLLLDPESRITA
AEALAFPFFSEFREPEEETEAPPYDHSLDEADQSLEQWKRLTFTEILTFQPAPAVAESKE
TAL

>Danio rerio_MAPK12b(ENSDARP_20408)
MSLRSRAGFYRQEINRTVWDVPERYRDLIQIGTGAYGTVCSAIDRKTGVRVAIKKLHRPF
QSRLFAKRAYRELRLLKHMKHENVIGLLDVFTSEILLDRFHDFYLVMPFMGTDLGKLMKM
ERLCEDRVQFLVYQILRGLKYIHSAGIIHRDLKPGNLAVNQNCELKILDFGLARQADSEM
TGYVVTRWYRAPEVILNWMHYSQTVDIWSVGCIMAEMLLGRTLFKGNDHLDQLREIMKIT
GTPAPDFITKLQSQDAKNYIRGLPKVPKKDLNTIFFKASSEAVSALELMLVLDPDKRVSA
AEALELPLFTEFREPEEETEALPYDHSMDNTELPLDQWKRHTFTEILSFQPPVTEIRDSK
ETSL

>Takifugu rubripes_MAPK12a(ENSTRUP_12265)
STMSKRVRPGYYRQDINKTKWEVPERYRDLRQVGTGAYGTVCSAVDNRTGSKVAIKKLYR
PFQSELFAKRAYRELRLLKHMKHENVIGLLDVFTADLSLDAFNDFYLVMPFMGTDLGKLM
KIQRLSEEKIQYLVYQMLKGLKYIHSAGIIHRDLKPGNLAINQDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILSWMHYTQTVDIWSVGCIMAEMLQGKPVFKGSDHLDQLNEIMK
ITGTPTQEFVTKLDSEDARRYIKGLPKIEKKDLQKVFSTTNPQAVSVLDRMLLLDPESRA
TAAEALALPYFTEFREPEEETEAQLYDHSLDNADLPLSQWKRHTFTEILTFKPVVSESKE
TPL

>Takifugu rubripes_MAPK12b(ENSTRUP_21551)
MALRSRTGFYRQEVNRTVWEVPERYRDLRQIGTGAYGTVCSAWDRRSGSQVAIKKLQRPF
QSKLFAKRAYRELRLLKHMKHENVIGLLDVFTAEVLDRLRDFYLVMPFMGTDLGKLMKVE
RLTEERVQFLVYQMLRGLKYIHSAGIIHRDLKPGNLAINPDCELKILDFGLARQADAEMT
GYVVTRWYRAPEVILNWMHYTQTVDIWSAGCIMAEMLLGRPLFKGNDHLDQLREIMKVTG
TPTGDFVVKLRSQDAKNYIRSLPKVPKKDLHSIFSKSSSNAVCVLEKMLLLDPEERVSAS
EALDLDFFSEFRDVDEETEALPYDQTLDNTDLQLDQWKRHTFTEILTFRPARETPL

>Tetraodon nigroviridis_MAPK12a(ENSTNIP_11198)
ARFLIFFAMSKRVRPGFHRQDINKTKWEVPERYRDLRQVGTGAYGTVCSAVDIRTGSKVA
IKKLYRPFQSELFAKRAYRELRLLKHMKHENVIGLLDVFTSDFSLDAFDDFYLVMPFMGT
DLGKVMKMQRLSEEKIQYLVYQMLRGLKYIHSAGIIHRDLKPGNLAINQDCELKILDFGL
ARQTDSTMTGYVVTRWYRAPEVILSWMHYTQTVDIWSVGCIMAEMLQGKPLFKGSDHLDQ
LNEIMKITGTPTQEFVAKLDSEDARRYIKGLQKIEKKDLQTVFSTTNPQAVSVLERMLLL
DPESRASAAEALALPYFSEFRDPEEETEAQPYDHSLDNADLPLSQWKRHTFTEILSFKPV
VSEFKETPL

>Gasterosteus aculeatus_MAPK12a(ENSGACP_17737)
MSKRIRPGYYRQDVNKTSWEVPERYRELKQVGTGAYGTVCSAVDSRTGTKVAIKKLYRPF
QSELFAKRAYRELRLLKHMKHENVIGLFDVFTADLSLDKFHDFYLVMPFMGTDLGRLMKL
QRLSEDKIQYLVYQMLKGLKYIHSSGIIHRDLKPGNLAINQDCELKILDFGLARQADSEM
TGYVVTRWYRAPEVILSWMHYTQTVDIWSVGCIMAEMLQGKPLFKGSDHLNQLTEIMKVT
GTPTQEFAAKLVSDDARGYVKSLPKVEKKDLHSVFSTTNPQAVAVLERMLLLDPESRVSA
EEALMLPYFTEFREPEEETVPQQYDHSLDNTDQSLAQWKRHTFTEILTFKPVVPDSKETA
LGLKIT

>Gasterosteus aculeatus_MAPK12b(ENSGACP_25266)
LSRCGMAVRSRTGYYRQEVNRTGWEVPERYRDLKQVGTGAYGTVCSAWDRRLGAQVAIKK
LHRPFQSKLFAKRAYRELRLLKHMKHENVIGLLDVFTAEIALDRLRDFYLVMPFMGTDLG
KLMKLERLSEDRVQFLVYQMLRGLKYIHSAGIIHRDLKPGNLAINPDCELKILDFGLARQ
ADAEMTGYVVTRWYRAPEVILNWMRYTQTVDIWSAGCIMAEMLLGRPLFKGNLDQLREIM
KITGTPAADFVVKLQSQDAKNYIRSLPKVPKKDLQSVFSKASSNAVCVLEKMLLLDPEQR
ANASEALDLPFFAEFRDTEEETEAQPYDQTMDNTDLPLDQWKRHTFTEILTFRPPRDSRE
TSL

>Oryzias latipes_MAPK12a(ENSORLP_20405)
TKMSLRVRPGYSRQEVNKTSWEVPDRYRDLKQVGSGAYGTVCSATDSRTGAKVAIKKLYR
PFQSEIFAKRAYRELRLLKHMKHENVIGLLDVFTADLSLDRFLDFYLVMPFMGTDLGKLM
KMHKLSEDKIQYLVYQMLKGLKYIHSAGIIHRDLKPGNLGINQDCELKILDFGLARQTDS
EMTGYVVTRWYRAPEVILSWMHYTQTVDIWSVGCIMAEMLQGKPLFKGNDHLDQLTEIMK
ITGTPSPEFLSKLVSEEAKKYLKSLPKQEKKDLQKVFPSSDVHAVSMMEKMLLLDPEKRV
TAAEALTLPYFTEFRDSEEEKEAQPYDHSLDNAELSVDQWKRHTFTEILTFKPVLPDSKE
TSL

>Oryzias latipes_MAPK12b(ENSORLP_11305)
MAIAARSRSGFYRQEVNRTVWEVPERYRDLKQIGTGAYGTVCSAWDRRTGAQVAIKKLHR
PFQSKLFAKRAYRELRLLKHMRHENVIGLLDVFTAEISLDRFRDFYLVMPFMGTDLGKLM
KMEKLTEDRVQFLVYQILKGLKYIHSAGIVHRDLKPGNLAINPDCELKILDFGLARQADA
EMTGYVVTRWYRAPEVILNWMHYTQTVDIWSAGCIMAEMLLGKPLFKGSDHLDQLREIMK
ITGTPSPDFVVKLQSQDAKNYIRSLPKVPKKDLHYIFSKASSNAVCVLERMLLLDPECRA
SASEALELPFFNEFRDIEEETEALPYDQTMDNTDLPLDQWKRHTFTEILTFRPPRDSKGT
SL

>Homo sapiens_MAPK13(ENSP_211287)
MSLIRKKGFYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPF
QSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIMGM
EFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEMT
GYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTG
VPGTEFVQKLNDKAAKSYIQSLPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAA
QALTHPFFEPFRDPEEETEAQQPFDDSLEHEKLTVDEWKQHIYKEIVNFSPIARKDSRRR
SGMKL

>Mus musculus_MAPK13(ENSMUSP_4986)
MSLTRKRGFYKQDINKTAWELPKTYLAPAHVGSGAYGAVCSAIDKRTGEKVAIKKLSRPF
QSEIFAKRAYRELLLLKHMHHENVIGLLDVFTPASSLRSFHDFYLVMPFMQTDLQKIMGM
EFSEDKVQYLVYQMLKGLKYIHSAGIVHRDLKPGNLAVNEDCELKILDFGLARHTDTEMT
GYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTG
VPGAEFVQKLKDKAAKSYIQSLPQSPKKDFTQLFPRASPQAADLLDKMLELDVDKRLTAA
QALAHPFFEPFRDPEEETEAQQPFDDALEHEKLSVDEWKQHIYKEISNFSPIARKDSRRR
SGMKLQ

>Gallus gallus_MAPK13(ENSGALP_1204)
MNFTRRRGFYRQELNRTIWELPRRYTSLHPVGSGAYGSVCSAIDKKTGEKVAIKKLCRPF
QSEIFAKRAYRELTLLKQMQHENVIGLLDVFTSAPSYHGFQDFYLVMPYMRTDLQKIMGH
EFSDEKIQYLVYQMLKGLKYIHSAGIIHRDLKPGNLAVNEDCQLKILDFGLARHADAEMT
GYVVTRWYRAPEVILNWMHYNQTVDIWSIGCIMAEMLTGKTLFKGKDYVDQLTQILKVTG
HPGDDFVEKLEDKAAKSYIKSLPKMPKKDLSVLFPTANPQAVDLLDKMLQLDVEKRLTAT
EALAHPYFDQFRDIEEETEAQQSYDDSLEREKLSIEEWKKHIYKEILSFSPIAQKDSKKR
SGMSL

>Anolis carolinensis_MAPK13(ENSACAP_16684)
MSFSRRRGFYKQEVNKIVWELPRRYTSIVSVGSGAYGSVCSSIDKKTGEKVAIKKLCRPF
QSEIFAKRAYRELTLLKHMQHENVIGLLDVFTSATSFEGFQDFYLVMPYMQTDLQKIMGH
QFSEEKIQYLIYQVLKGLKYIHSAGIIHRDLKPGNLAVNEDCALKILDFGLARHTDTEMT
GYVVTRWYRAPEVILNWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTLILKVTG
SPGEEFIQKLEDKAAKSYIQTMPKIPKMDLSRLFPRASPLAVDLLDKMLQLDVEKRLTAT
QALAHPYFEPFRDVEEETEAQHSYDDSVGAQKLSINEWRRHIYNEILTFSPIARKDSKRR
SGMTL

>Xenopus tropicalis_MAPK13(ENSXETP_923)
MSSSVKCKFRKEEVNKTLWEIPLRYASLCLVGSGAYGSVCSAIDLKTGEKVAIKKLSRPF
QSEIFAKRAFRELTLLKHMNHENVIGLLDVFTSATSFNDFHNFYLVMPYMQIDLQKIMGH
HLSEDKVQYLVYQMLCGLKYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARHADAEMT
GYVVTRWYRAPEVILNWMHYNKTVDIWSVGCIMGEMLTGKTLFKGKDCILDLDQLTQILK
VTGVPGPEFIQKLEDMAAKKYIQSLPKIPKKEFSLLFPNASDLAVDLLEKMLELDVEKRL
TATEALEHPYFDEFHDADEETEAPPYDDSLEGEKLSVEEWRKYTYEEVINYTPILRKDSK
RKSGMSIKDEFEGTCPLP

>Danio rerio_MAPK13a(ENSDARP_75784)
MESRVEFSREEINSTVWEVPAKYVCLKQIGTGAYGSVCSSINNKTKEKVAIKKLHRPFQS
EIFAKRAYRELRLLKHMKHENVIGLLDVFTPATRLDEFQDFYLVMPYMYTDLSKVKGLLT
EDRIQFLVYQMLCGLKYIHGAGIIHRDLKPGNLAVNQDCELKILDFGLARHTDAEMTGYV
VTRWYRAPEVILNWMHYTQTVDIWSVGCIMGEMFNGKTLFKGKDYMDQLTQIMKVAGTPG
PEFVEKLESPEAKSYVRSLPHYPHRDFSTLFPRASKKAVELLEKMLVLDADARLTASGAL
AHSYFDGLRDPDDWPEPTAYDDSYDNATLPLEEWKRLSFKEVRSFVPFPRRDSKRRNTLT
MS

>Takifugu rubripes_MAPK13a(ENSTRUP_21639)
CIMEAHAHFSREEINNTVWEVPEKYTRLKQIGTGAYGSVCSTINEKTKEKVAIKKLHRPF
QSEIFAKRAYRELRLLKHMKHENVIGLLDVFTPALGLDEMQDFYLVMPYMFTDLSKVRGP
LSEDKVQFLIYQTLCGLRYIHKAGIIHRDLKPGNLAVNQDCELKILDFGLARSADAEMTG
YVVTRWYRAPEVILNWMHYTQTVDIWSVGCIMAEMIHGKTLFKGKDYMDQLTQIMKVTGV
PGPEFIQKLDSIEAKNYVKALPRYPRKDFSTLFPKASAKGIDLLEKMLVLDGDERLTAEL
ALEHSYFDSLRDPDDFPEPTPYDDSHDNATLSLDEWKRLCFREVKSFVPFPRRDSKRKNT
LTMS

>Tetraodon nigroviridis_MAPK13a(ENSTNIP_13818)
ASSPLVMEAHAHFSREEINNTVWEVPEKYTRLKQIGTGAYGSVCSAINERTKEKVAIKKL
HRPFQSEIFAKRAYRELRLLKHMKHENVIGLIDVFTPASGLDEMQDFYLVMPYMFTDLSK
VRGPLSEDKVQFLIYQTLCGLRYIHKSGIIHRDLKPGNLAVNQDCELKILDFGLARSADA
EMTGYVVTRWYRAPEVILNWMHYTQTVDIWSVGCIMAEMINGKTLFKGKDYMDQLTQIMK
VTGVPGPEFVQKLDSIEAKNYVKALPRYPRKDFSTLFPKASANGIDLLEKMLVLDGDERL
TADLALEHPYFDSLRDADDFPEPTPYDDSHDNATLSLDEWKRLCFREVKSFVPFPRRDSK
RKNTPYNVSL

>Gasterosteus aculeatus_MAPK13a(ENSGACP_6498)
ILLTMEARAHFYREEINNTAWEVPEKYTRLKQIGTGAYGSVCSAINEKTKEKVAIKKLHR
PFQSEIFAKRAYRELRLLKHMKHENVIGLLDVFSSASSLDDMQDFYLVMPYMFTDLSKVR
GHLTEDKVQFLVYQMLCGLRYIHKAGIIHRDLKPGNLAVNQDCELKILDFGLARSTDAEM
TGYVVTRWYRAPEVILNWMHYTQTVDIWSVGCIMAEMINGKTLFKGRDYMDQLTQIMKVT
GVPGAEFTQKLDSQEAKNYIKALPRYPRKDFSTLFPRASAMGIDLLEKMLVLDGDERPTA
ELALEHPYFDSLRDLEDLPPPAPYDDSHDNATLSLDEWKRLCFKEVRSFVPFPRRDSKRK
NTLTMSP

>Oryzias latipes_MAPK13a(ENSORLP_486)
LLFIMDAKTHFTREEINSTVWEVPEKYTLLKQVGTGAYGSVCSAINGKTKEKVAIKKLHR
PFQSEIFAKRAYRELRLLKHMKHENVIGLLDVFTLACCLDEFQDFCLVMPYMYTDLSKVR
GSLSDDKVQFLVYQMLCGLRYIHKAGIIHRDLKPGNLAVNPDCQLKILDFGLARSTDAEM
TGYVVTRWYRAPEVILNWMHYTQTVDIWSVGCIMGEMINGKTLFKGKDYMDQLTQILKVT
GVPGPEFVQKLDSPEAKTYVKNLPRYPRKAFSSLFPKASELAIDLLEKMLVLDGDERPTA
EIALEHQYFDSLRDPDDLPEPVPYDDSHDNATLSLDEWKRLCFKEVKSFVPFPRRDSKRK
NTLTMSS

>Homo sapiens_MAPK14(ENSP_229795)
MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTG
TPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES

>Mus musculus_MAPK14(ENSMUSP_4990)
MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTG
TPPAYLINRMPSHEARNYIQSLAQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES

>Gallus gallus_MAPK14(ENSGALP_1201)
AAEMSQERPKFYRQELNKTVWEVPERYQNLSPVGSGAYGSVCSAFDTKTGLRVAVKKLSR
PFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPAKSLEEFNDVYLVTHLMGADLNNIV
KCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDD
EMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILR
LVGTPGPELLKKISSESARNYIQSLSYMPKMNFENVFIGANPLAVDLLEKMLVLDTDKRI
TAAEALAHAYFAQYHDPDDEPVADPYDQSFESRELEIEEWKSLTYDEVISFVPPPLDQEE
MES

>Anolis carolinensis_MAPK14(ENSACAP_16739)
MTQERPKFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCSAFDTKTGLRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPAKSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
TPGPELLKKISSESARNYIQSLSYMPKMNFENVFIGANPLAVDLLEKMLVLDTDKRITAA
EALAHTYFAQYHDPDDEPVADPYDQSFESRELDIEEWKSLTYDEVVSFVPPPLDQEEMES

>Oryzias latipes_MAPK14a(ENSORLP_8135)
SVGEVGAVVSAGMSQKERPNFYRQEVNKTIWEVPDRYQNLSPVGSGAYGSVCSAYDTKTG
LKVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPATSLKEFTDVYFVNH
LMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKIL
DFGLARLTDDEMTGYVATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAELLTGRTLFPGTD
HIDQLKLIMMLVGTPGPELLMKISSESARTYISSLPHMAKRNFADVFIGANPLDKAVDLL
EKMLVLDTDRRITAAEALEHPYFAQYHDPDDEPEAEPYDQSFESRDLNIKEWKRLTYEEL
CSFEPPVFN

>Oryzias latipes_MAPK14b(ENSORLP_20176)
MLHRNVIGLLDVFTPATSLDEFSDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRG
LKYIHSAGIVHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNW
MHYNMTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLIMMLVGTPGPELLMKISSEPARN
YINSLPHMPKRNFADVFIGANPLAVDLLEKMLVLDTDKRITASEALAHPYFAQYHDPDDE
PEAEPYDQSFESRELEIEEWRSLIYDEVLSFEPPSLDGDEMES

>Ciona intestinalis_(ENSCSAVP_5272)
MSDKRPPEVVRGQVFDVAPRYTSLSYIGEGAYGMVCSATDGQNGQKVAIKKISPFEHQTY
CQRTLREIRILISFNHENIISIKDIIRAPTLAEMKDVYIVQDLMETDLYKLLKTQHLSND
HICYFLYQILRGLKYIHSANVIHRDLKPSNLLLNTTCDLKICDFGLARVADPEHDHTGFL
TEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMISNRPIFPGKHYLDQLNHILGIL
GSPSEEDLNCIINEKARAYLMSLPNKPRLSWSRLYSKADEKALDLLDRMLTFNPTKRINV
DDALAHPYLEQYYDPADEPVTEKPFTFEEEFDDLPKERLKELIFQVSPCR

>Ciona intestinalis_(ENSCINP_18935)
QADEGMSNGKNKGANAPTGAATTGKDTANTEFYTVQVSDSVFTVLKRYQSLKPIGSGAQG
MVCAAHDTVLGQHVAIKKLSRPFQNPTHAKRAYRELVLMRAVNHKNIIGLLNVFSPQSSY
EDFSHVYLVMELMDASLCQVIQMDLDHERLSYLLYQLLCGIKHLHSAGIIHRDLKPSNIV
VRSDCTLKILDFGLARTAGGSFMMTPYVVTRYYRAPEVILGMGYQEVVDIWSVGCIFGEM
IRGQVLFPGNDHIDQWNKITEQLGTPSEDFINKLQPTVRNYVLNRPFQRGHPIHRLFPDS
LFPADSESNGRLRSSQARDLLAKMLVVDPIGRITVDDALQHPYIKIWYDPSEVEGPGPKV
DGGSIDEVDYSVEKWKEVIWTEVKLWDTVDTTVPNPVIPLSTAVPDQPAEKLEPEKAESN
PDVPAATAQVVKAETEG

>Strongylocentrotus purpuratus_(XP_786040)
MAGTKLNHHQPNHHQFNYHQLNSQFYHVTVGDTHFQILKRYKNLKSVGSGAQGLVVAAYDVLTNQSVAIK
KLSRPFQNVTHAKRAYREYILMKLCNHKNIIGLLNVFTPQRTFDDFADIYLVMELMDASLVQVVQMDLDH
ERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKTDCSLKILDFGLARTASTSFMMTPYVVTRYYRAPE
VILGMGYKENVDIWSIGCIFGEMIRGQVMFPGSDHIDQWNKIADLLGTPTDIFLSRLQPMVKQYVENRTK
CPGYSFEMLFPDELFYQAESSTEKTKLCVAQARNLLSKMLIVDPEQRISVDEALQHPYINVWFDPGEVYG
PPPIPYDHSIDDGGDHILEEWKDGTSHPIEEEKDEREHTLEQWKGF

>Drosophila melanogaster_(FBpp0080111)
MSRKMAKFYKLDINRTEWEIPETYQNLQPVGQGAYGQVCKAVVRGTSTKVAIKKLARPFQ
SAVHAKRTYRELRLLKHMDHENVIGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLNNII
RTQKLSDDHVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPAES
EMTGYVATRWYRAPEIMLNWMHYNQTADIWSVGCIMAELLTGRTLFPGTDHIHQLNLIME
VLGTPADEFMSRISSESARNYIRSLPVMPRRNFRDIFRGANPLAIDLLEKMLELDADKRI
TAEQALAHPYMEKYHDPTDEQTAALYDQSFEENELPVEKWREMVFSEVTAFKPTAAFAEL
LPKEQ

>Drosophila melanogaster_(FBpp0291573)
MTTAQHQHYTVEVGDTNFTIHSRYINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQ
NVTHAKRAYREFKLMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQMD
LDHDRMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGTTFMM
TPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLG
TPSPSFMQRLQPTVRNYVENRPRYTGYSFDRLFPDGLFPNDNNQNSRRKASDARNLLSKM
LVIDPEQRISVDEALKHEYINVWYDAEEVDAPAPEPYDHSVDEREHTVEQWKELIYEEVM
DYEAHNTNNRTR

>Apis mellifera_(XP_6557304)
MPYLGPDMTTRLSAMFYTVEVGDTRFTILKRYQNLKPIGSGAQGIVCAAYDTVTAQNVAIKKLSRPFQNV
THAKRAYREFKLMKLVNHKNIIGLLNAFTPQRSLDEFQDVYLVMELMDANLCQVIQMDLDHERMSYLLYQ
MLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGTTFMMTPYVVTRYYRAPEVILGMGYKE
NVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPAQEFMQRLQPTVRNYVENRPRYPGYPFDRL
FPDVLFPSDSSEHNRLKASQARDLLSRMLVIDPERRISVDDALLHNYINVWYDEGEVNAPAPGPYDHSVD
EREHTVDQWKELIYQEVMEYETSHNPTTVAQTSESGESR

>Apis mellifera_(XP_395384)
MPQFHKVEINRTEWEVPERYQMLTPVGSGAYGQVCSALDTKTGQKVAIKKLARPFQSAVHAKRTYRELRM
LKHMNHENIIGLLDVFHPSSSLEDFQQVYLVTHLMGADLNNIVRTQKLSDDHVQFLVYQIFRGLKYIHSA
GIIHRDLKPSNIAVNEDCELKILDFGLARPTENEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMA
ELLTGRTLFPGTDHIHQLNLIMEILGTPRDEFMQKILSESARNYIQSLPPLKKKNFKDVFRGANPLAIDL
LELMLELDAEKRITAEQALAHPYLAQYADPTDEPVSLPYDQSFEDMDLPVEKWKELVYHEVINFVPQQLP
TIASGIESTS

>Anopheles gambiae_(XP_310236)
MSSRHAFYTVEVGDTKFTILKRYQNLKPIGSGAQGIVCAAYDTVTQQNVAIKKLSRPFQNVTHAKRAYRE
FKLMKLVNHKNIIGLLNAFTPQRTLEEFQDVYLVMELMDANLCQVIQMDLDHERMSYLLYQMLCGIKHLH
SAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTTFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGC
IMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSQNFMTRLQPTVRNYVENRPRYSGYAFDRLFPDVLFPTD
SNEHNRLKASQARDLLSRMLVVDPEHRISVDQALVHSYINVWFDESEVNAPAPGPYDHSVDEREHTVEQW
KELIYQEVMEYEARNNLADGEGAPR

>Caenorhabditis elegans_(B0218)
MFPQTTMDHILHPTPREGYYVVELNRSVWVVPNYYINLTPIGTGAYGTVCAAECTRSGTR
VAIKKFNRPFQSIIHARRTYRELRLLRCMCHENIIDLLDVFTPNENVNDIEDVYFVSMLM
GADLSNILKIQRLNDDHIQFLVYQILRGLKYIHSADIIHRDLKPSNIAVNEDCELKILDF
GLARQTDSEMTGYVATRWYRAPEIMLNWMHYTQTVDVWSVGCILAELITGKTLFPGSDHI
DQLTRIMSVTGTPDEEFLKKISSEEARNYIRNLPKMTRRDFKRLFAQATPQAIDLLEKML
HLDPDRRPTAKEAMEHEYLAAYHDETDEPIAEEMDLNDDVRADTIDEWKKIIWEEISDFQ
KNVAFADEEEDEEKMES

>Nematostella vectensis_(XP_1637588)
MFYTAQVGDTIFIVLKRYQNLQPIGSGAQGMVCAAIDTVTGEKVAIKKLSRPFQNVTHAKRAFRELVLMR
MVNHKNIIGLLNVFTPDRTLEQFNDLYLVMELMDASLCQVIHMDLDHERLSYLLYQMLCGVKHLHDADII
HRDLKPSNIVVKSDCSLKILDFGLARTAGSAFMMTPYVVTRYYRAPEVILGMGYCDNVDVWSIGCILAEM
IRGHVMFPGTDHIDQWNKVTEQLGTPSESFLNQLQPSVRMYCTRRPKQPGFSFEALFPDDLFPPENKLKA
NPTYTLIKPMYVTTQISQPYLSINQTYVRYDPNKPARPKHLSNLCTKYDHSIDEQEHSVEEWKSK

>Hydra magnipapillata_(XP_2156118)
MLTHKPQTVISLLDTFTPQQTLEEFQDVYLVTCLMGADLNNITKVQTLTDEHVQFLVYQLLRGLKYIHSA
GIIHRDLKPGNVAVNENCELKILDFGLARMSDDSMTGYVATRWYRAPEIMLNWMQYNSQVDIWSVGCIMA
ELITGKTLFPGDDHIDQLTKIMQLVGKPTDDFLAKISSANARSYINSMPNYVRQDFDKVFPTATAQAKNI
LHHMLLLDPEKRFSAEQCLQHPYFSVYHDPDDEPTAPLFEEGAELNECSIDTIKALMLNEIKNFVYKPPP
EEVME

>Hydra magnipapillata_(XP_2156470)
MFYSVQIGDTIFTILNRYQNLHPIGSGAQGMVCCAAYDTVIKQKVAIKKLSRPFQNVTHAKRAFRELKLM
KITNHKNIIGLLNVFTPDKSLEDFMDLYLVMELMDASLCQVVQMDLDHERLSYLLYQMLCGIKHLHSAGI
IHRDLKPSNIVVKSDCSLKILDFGLARTAGSAFTMTPYVVTRYYRAPEIILGMGYSENVDVWSIGCIFGE
MIRGSVMFPGTDHIDQWNKVTELLSTPPQSFFDRLQPSVRMYCANRPKQKGYTIDELFPEDLFPVGNKQK
VNQARDLLLKMLVVDPMKRITITQALNHPYVHVWYDAEEVEAPAPMQYDHKIDEIDHTVEEWKAEPREII
SLICFV

>Amphimedon queenslandica_MAPK8(XP_3384215)
MADFYTTQVGDTLFTIPRRYQDLKPLGHGAQGVVCSAKDSVRGERIAIKKLVKPFQNETYAKRAFRELKL
MKMVNHKNVIGLLNLFSPAHSIEDFEDVYIVMELMDANLCRVIGIELDHDRMSYLLYQLLCGIKHLHSAG
IIHRDLKPSNIVVKEDCSLKILDFGLARAADKAFMMTPYVVTRYYRAPEVIVGMKYKENVDIWSVGCIFA
EIVRGDILLPGRDYIDQWNKVTQILGTPPQEFFKQLQPSVRMYCESQPRHKGKSWNELFPDDVFPNDSKE
DAHKTRLAVDLLTKMLQIEPTRRVTVDEALKHPYVSIWYDPSEADAPPPPKYDHCLDEKNIPLAQWKKLI
YEEVISFDERRDAKR