>Homo sapiens_GRK4(ENSP_381129)
MELENIVANSLLLKARQGGYGKKSGRSKKWKEILTLPPVSQCSELRHSIEKDYSSLCDKQ
PIGRRLFRQFCDTKPTLKRHIEFLDAVAEYEVADDEDRSDCGLSILDRFFNDKLAAPLPE
IPPDVVTECRLGLKEENPSKKAFEECTRVAHNYLRGEPFEEYQESSYFSQFLQWKWLERQ
PVTKNTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRIKKRKGEAMALNEKRILE
KVQSRFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGL
EDLQRERIVYRDLKPENILLDDRGHIRISDLGLATEIPEGQRVRGRVGTVGYMAPEVVNN
EKYTFSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSI
CRMLLTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCPDPHAVYCKDVLD
IEQFSVVKGIYLDTADEDFYARFATGCVSIPWQNEMIESGCFKDINKSESEEALPLDLDK
NIHTPVSRPNRGFFYRLFRRGGCLTMVPSEKEVEPKQC

>Mus musculus_GRK4(ENSMUSP_1112)
MELENFVANNLLLKARLGFNKQTGRSKKWRELLKFPPVSMCTELRWSIEKDFSSLCDKQP
IGRLLFRQFCDTKPDLKRCIEFLDAVAEYEVTIEEEQREFGLAIFSRFFKEKSEVPLPEI
PPDIVKECKWNLKQNSPSQNVFEECAGIVCKYLSETPFEEYQESTYFNRFLQWKWLERRP
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKRILEK
LHSRFVVSLAYTYETKDALCLVLTIMNGGDLKYHIYNLGDPGFEEPRAVFYAAELCCGLE
DLQRKRIVYRDLKPENILLDDHGHIRISDLGLAMEVPEGEMVRGRVGTVGYMAPEIINHE
KYTFSPDWWGLGCLIYEMIAGHSPFRKYKEKVNREELERRVKNETEEYSERFSEDAKSIC
SMLLIKDPSKRLGCQRDGVSAVKQHPIFKDINFSRLEANMLDPPFIPDPQAIYCRNILDI
GQFSVVKGVNLDTNDEIFYAEFATGSVTIPWQNEMIESGCFKDLNENEDDLSSLEKYKMC
SSILRPKRNFFRRLFRRTGCLNIALSEEREPTEH

>Rattus norvegicus_GRK4(ENSRNOP_15894)
MELENFMANTLLLKARQGFTKKTGRSKKWRELLKLPPVSMCSDLRHSIEKDFSSLCDQQP
IGRLLFRQFCNTKPDLKRCIEFLDAAAEYEVTIEEEQREFGLSIYSRFFKENSEVSLPQI
PPDLVKECKCNLKQSSPSQNVFQDCAGVIYKYLSEKPFEEYQESTYYNRFLQWKWLERRP
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKRILEK
LHSRFVVSLAYTYETKDALCLVLTIMNGGDLKYHIYNLGNPGFEEQRAVFYAAELCCGLE
DLQRERIVYRDLKPENILLDDHGHIRISDLGLALEIPEGEMVRGRVGTVGYMAPEIISHE
KYTFSPDWWGLGCLIYEMIAGHSPFRKYKEKVNREEMERRVKTETEEYSERFSENAKSIC
SMLLTKDPSKRLGCQSDGASAVKQHPIFKDINFSRLEANMLDPPFCPDPEAIYCKDILDI
GQFSVVKGVNLDTNDEIFYTQFATGCVTIPWQNEMIESGCFKDLNEYEDKGLSPLEKHKI
CSCILRPKRNFFHRLFRRAACLNIAHSEEREPTEH

>Danio rerio_GRK4(ENSDARP_110128)
MEIENIVANTVLLKAREGGGGKRNGRSKKWKEMLKLPHISQCEELRRTIERDYTSLCEKQ
PIGRQLFRQFCDTQPKLRRCIEFLDSVAMYQVAPDEKRRDAGLNILDTYFNNGSAAHLPE
MAQDVVGECRQKLEQSPCKELFQECTRIVREYLSGAPFSAYQETMYFSRFLQWKWLERQP
VTKNTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRVKKRKGEAMALNEKRILEK
VNSSFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNSGFDEQRAIFYAAEICCGLE
DLHRERIVYRDLKPENILLDDRGHIRISDLGLAVQIPEGETIRGRVGTVGYMAPEVIQNE
SYTFSPDWWGLGCLIYEMIQGQSPFRRRKERVKREEVDRRVCEDQEEYTEKFSEDAKDIC
RQLLCKDPKERLGCRGSGAAEVKLHPIFRNINFKRLEANMLDPPFCPDPRAVYCKDVLDI
EQFSTVKGVNLDPTDDDFYHKFVTGSVSIPWQNEMIEMECFKEINVFEMDGALCADLDVN
RPNPAPKRGFFYRLFHREVCFGSANSEEEEKEEKEEEPS

>Takifugu rubripes_GRK4(ENSTRUP_14080)
GSRILTMEIENIVANTVLLKAREDKDQISPAPSVKVLNICNWKPPPPLPTQPGQHCGGGK
RNGRSKKWKEMLKLPHISQCEELRRTIERDYTSLCEKQPIGRLLFRQYCDTRPELKRCIE
FMDAVAMYQLAPDEERRDCGLNLLDTYFNNGSAAHLPDIPLEVVAGCRERLEQSPCKELF
DDCTKEQRVLHLWKLSGLKARSKNSHPSAGGNHRIVRDYLSGVPFSSFQESMYFSRFLQW
KWLERQPVTKNTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRVKKRKGEAMALN
EKRILEKVNSSFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNSGFDEQRAIFYAA
EICCGLEDLHRERIVYRDLKPENILLDDRGHIRISDLGLAVQIPEGETIRGRVGTVGYMA
PEVIQNESYTFSPDWWGLGCLIFEMIQGQSPFRKRKERVKREEVDRRVREDLEEYSDKFS
EEAKDICRQLLAKDPKERLGCQGRGATEVKEHPIFRNINFKRLEANMLDPPFCPDPRAVY
CKDVLDIEQFSTVKGVNLDPTDDDFYHKFVTGSVSIPWQNEMIEMECFKEINIYETDGKL
CSDLDVNRPNPPPKRGFFYRLFRRE

>Tetraodon nigroviridis_GRK4(ENSTNIP_15013)
ADLQQIVTNNLLCLPRGGGGKRNGRSKKWKEMLKLPHISQCEELRRTIERDYTSLCEKQP
IGRLLFRQYCDTRPELKRCIEFMDAVATYQLAPDEERRDCGLNVLDTYFNNGSAAHLPDI
PLEVVAGCRERLEQSPCKELFDDCTKIVRDYLSGVPFSSYQESMYFSRFLQWKWLERQPV
TKNTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRVKKRKGEAMALNEKRILEKV
NSSFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNSGFDEQRAIFYAAEICCGLED
LHRERIVYRDLKPENILLDDRGHIRISDLGLAVQIPEGETIRGRVGTVGYMAPEVIQNES
YTFSPDWWGLGCLIFEMIQGQSPFRKRKERVKREEVDRRVREDHEEYSDKFSEEAKDICR
QLLAKDPKERLGCQGRGAAEVKGHPIFRNINFKRLEANMLDPPFCPDPRAVYCKDVLDIE
QFSTVKGVNLDPTDDDFYHKFVTGSVSIPWQNEMIEMECFKEINIYETDGKLCSDLDVNR
PNPPPKRGFFYRLFRREVCFKSGYSDDEIEEPSRL

>Gasterosteusaculeatus_GRK4(ENSGACP_24254)
MEIENIVANTVLLKAREGGGGKRNGRSKKWKEMLKLPHISQCEELRRSIERDYTSLCEKQ
PIGRLLFRQYCDTRPELKRCIEFMDTVAMYQLAPDEKRRDYGLNVLDTYFNNGSAAHLPD
VPQEMVAGCREKLEQSPCKELFNDCTKIVRDYLGGAPFSSYQESMYFSRFLQWKWLERQP
VTKNTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRVKKRKGEAMALNEKRILEK
VNSSFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNSGFDEQRAIFYAAEICCGLE
DLHRERIVYSRDLKPENILLDDRGHIRISDLGLAVQIPEGETIRGRVGTVGYMAAPEVIQ
NESYTFSPDWWGLGCLIFEMIQGQSPFRKRKERVKREEVDRRVREDQEEYSDKFVEEAKD
ICRQLLTKDPKERLGCQGRGAIEVKQHPIFRNINFKRLEANMQDPPFTLSQPRAVYCKDV
LDIEQFSTVKGVNLDPTDDDFYYKFVTGSVSIPWQNEMIEMECFKEINVYETDGTLCSDL
DVNRPNPPPKRGFFYRLFRREVCFKSGYSDDEIEEPSRL

>Homo sapiens_GRK6(ENSP_433511)
MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ
PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE
VPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQP
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK
VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE
DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNE
RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLC
SQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDI
EQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWK
GQPPAPPKKGLLQRLFSRQRIAVETAATARKSSPPASSPQPEAPTSSWR

>Mus musculus_GRK6(ENSMUSP_1115)
MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ
PIGRLLFREFCATRPELTRCTAFLDGVSEYEVTPDEKRKACGRRLMQNFLSHTGPDLIPE
VPRQLVSNCAQRLEQGPCKDLFQELTRLTHEYLSTAPFADYLDSIYFNRFLQWKWLERQP
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK
VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE
DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVRNE
RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVAEEYTDRFSSQARSLC
SQLLSKDPAERLGCRGGGAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDI
EQFSTVKGVDLEPTDQDFYQKFATGSVSIPWQNEMVETECFQELNVFGLDGSVPPDLDWK
GQPTAPPKKGLLQRLFSRQRIAVGTAATVRKSSPPASSPQAEAPTGGWR

>Rattus norvegicus_GRK6(ENSRNOP_50134)
MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ
PIGRLLFREFCATRPELTRCTAFLDGVAEYEVTPDEKRKACGRRLMQNFLSHTGPDLIPE
VPRQLVSNCAQRLEQGPCKDLFQELTRLTHEYLSMAPFADYLDSIYFNRFLQWKWLERQP
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK
VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE
DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNE
RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVAEEYTDRFSPQARSLC
SQLLNKDPAERLGCRGGGAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDI
EQFSTVKGVDLEPTDQDFYQKFATGSVSIPWQNEMVETECFQELNVFGLDGSVPPDLDWK
GQPTAPPKKGLLQRLFSRQDCCGNCSDSEEELPTRL

>Gallus gallus_GRK6(ENSGALP_22712)
MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISLCEDLRQALERDYHSLCEKQ
PIGRMLFRQFCETRPELSRCVKFLDAVAGYEVAPDEKRKECGQHLIEKYLKPKSEDYVPE
VPSQLVDACCERLEQEPSKELFKESTKLIHDYLSVAPFADYLDSLYFNRFLQWKWLERQP
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK
VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGEAGFEEPRAAFYAAEICCGLE
DLHQERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNE
RYTFSPDWWALGCLVYEMIEGQSPFQQRKKKIKREEVERLVKDVQEEYSEKFSPCARSLC
TMLLCKDPLERLGCRGAGAREVKEHPLFKHLNFRRLEAGMLDPPFKPDPQAIYCKDVLDI
EQFSTVKGVELEPTDNDFYQKFATGSVPIPWQNEMIETDCFKELNVFSTDGTVPPDLDWK
GQPSPQPKKGLLQRFFSRQRTVVGTAATVRKSPPGLPAAQPLPQDLAGSWT

>Anolis carolinensis_GRK6(ENSACAP_6115)
MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHVSQCEDLRHALEGDYHSLCEKQ
PIGRLLFRQFCETRLELMRCVKFLDAVAEYEVTPDENRKECGQQLIDTYLNPQSADHVPE
VPLELVTLCSERLEEEEPGKELFKESTKLIHDYLSVAPFADYLDSIYFNRFLQWKSLERQ
HVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILE
KVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGEAGFEEPRAVFYAAEICCGL
EDLHHERIVYRDLKPENILLDDHGHIRISDLGLAVYVPEGQTIKGRVGTVGYMAPEVVKN
ERYTFSPDWWALGCLLYEMIEGQSPFQQRRKKIKREEVERLVKEVQEEYSEKFSPASRSL
CSMLLCKDPMDRLGCGDAGAQGVKEHPLFKHLNFKRLEAGMLDPPFKPDPQAIYCKDVLD
IEQFSTVKGVELEPTDHDFYHKFATGSVPIPWQNEMIETECFKELNVFGPDGAVPPDLDW
KGQQPTVPKKGLLQRLFSRQDCCGNCSESEEEPTRL

>Danio rerio_GRK6(ENSDARP_22046)
MELENIVANTVLLKAREGGGGNRKGKSKKWKQMLQFPHISLCEELRQTIEKDYNSLCERQ
PIGRLLFRQFCDTRPELRRCVRFLDAVAEYEVTPDEKRKECGQELLDKYLNTKSEDYIPE
VTEEMVTKCADRLQQEACKELFMECTKLIHDYLSVAPFADYLDSMYYSRFLQWKWLERQP
ITKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGESMALNEKQILEK
VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGEAGFDEKRAVFYAAEICCGLE
DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNE
RYTFSPDWWALGCLLYEMIEGQSPFQQRKKKIKREEVERLVKEVEEEYSSKFSEDAKSLC
KMLLAKDPSERLGCQGGGASEVKAHLIFRSINFKRLAAGMLEAPFIPDPQAIYCKDVLDI
EQFSTVKGVELEPKDDSFYSKVSTGSVPIPWQNEMIETECFKELNILNLDGTVPPDLDWR
GQPSPPPKQGLLQRLFGRQDCCGNCSDSEEEPTRL

>Takifugu rubripes_GRK6(ENSTRUP_2422)
MELENIVANTVLLKAREGGGGNRKGKSKKWKQMLQFPHISMCEELRQNTEKDYSTLCERQ
PIGRLLFRQFCDTRPELRCCVKFLDAVAEYEVTPDEKRRECGQELVNKYFNPKSEDHVPE
VEEAMLVQCADRLQQEACKELFKDCTKLIHDYLSMAPFADYLDSMYYNRFLQWKWLERQP
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGESMALNEKQILEK
VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGESGFDEKRAVFYSAEICCGLE
DLHRERIVYRCRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVK
NERYTFSPDWWALGCLLYEMIEGQSPFQQRKKKIKREEVEKLVREVEEEYSSKFSEDAKS
LCKMLLAKDPKVRLGCQGNGASEVKAHPIFRSINFKRLEAGMLEPPFIPDPQAIYCKDVL
DIEQFSTVKGVDLEPKDESFYSKVSTGSVSIPWQNEMIETGCFAELNVFYQDGTVPPDLD
WRGQPSPPPKQGLLQRLFGRQFSLTGVCVTDVGASAPPEQSPAVKVPCWR

>Gasterosteusaculeatus_GRK6(ENSGACP_27510)
MELENIVANTVLLKAREGGGGNRKGKSKKWKQLLQFPHISLCEELRQTTEKDYSSLCERQ
PIGRLLFRQFCETQPELRRCVKFLDAVAEYEVAPDEKRKECGQELVNKYFDPKVEDYVPE
VEQAMMAQCAERLQQEACKELFKDCTKLIHGYLSVAPFADYLDSMYYNRFLQWKWLERQP
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGESMALNEKQILEK
VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGDAGFDEKRAIFYSAEICCGLE
DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNE
RYTFSPDWWALGCLLYEMIEGQSPFQQRKKKIKREEVERLVREVEEEYSSKFSEDAKSLC
RMLLAKDPAERTGCQGGGASEVKAHTIFCSINFKRLVAGMLQAPFTPDPQAIYCKDVLDI
EQFSTVKGVELEPKDESFYSKVSTGCVSIPWQDEMIETECFTELNVFHQDGTVPPDLDWR
GQPSPPPKQGLLQRLFGRQDCCGNCSDSDESPTRL

>Homo sapiens_SGK3(ENSP_379842)
MQRDHTMDYKESCPSVSIPSSDEHREKKKRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNT
LKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMD
SPKHQSDPSEDEDERSSQKLHSTSQNINLGPSGNPHAKPTDFDFLKVIGKGSFGKVLLAK
RKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVL
DFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHV
VLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPP
FYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGAKEDFLEIQNHPFFE
SLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYSVCVSSDYSIVNASVLEADD
AFVGFSYAPPSEDLFL

>Mus musculus_SGK3(ENSMUSP_95437)
MQRDCIMDYKESCPSVSIPSSDEHREKKKRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNS
LKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMD
SPRHQSDPSEDEDERSTSKPHSTSRNINLGPTGNPHAKPTDFDFLKVIGKGSFGKVLLAK
RKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVL
DFVNGGELFFHLQRERSFPEPRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSMGHV
VLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPP
FYCRDVAEMYDNILHKPLNLRPGVSLTAWSILEELLEKNRQNRLGAKEDFLEIQNHPFFE
SLSWTDLVQKKIPPPFNPNVAGPDDIRNFDAVFTEETVPYSVCVSSDYSIVNASVLEADD
AFVGFSYAPPSEDLFL

>Rattus norvegicus_SGK3(ENSRNOP_64540)
MQRDCTMDYKESCPSVSIPSSDEHREKKKRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNS
LKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMD
SPRHQSDPSEDEDERSTPKPHSTSRNINLGPTGNPQSPPPPVFLLKYLRKGRIIKVLLAK
RKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVL
DFVNGGELFFHLQRERSFPEPRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSMGHV
VLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPP
FYCRDVAEMYDNILHKPLNLRPGVSLTAWSILEELLEKNRQNRLGAKEDFLEIQNHPFFE
SLSWTDLVQKKIPPPFNPNVAGPDDIRNFDAVFTEETVPYSVCVSSDYSIVNASVLEADD
AFVGFSYAPPSEDLFL

>Gallus gallus_SGK3(ENSGALP_30252)
MDLKESCPSVSIPSSDEHREKKKRFTVYKVLVSVGRNEWFVFRRYAEFDKLYNTLKKQFP
TMNLKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRQPELCNHPDVRAFLQMDNPKHQS
DPSEDEDERSNQKLNSTSPNINLGPSGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGK
YYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGG
ELFFHLQRERSFPEHRARFYAAEIASALGYLHSINIVYRDLKPENILLDSLGHVVLTDFG
LCKEGIASSDTTATFCGTPEYLAPEVIKKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDV
AEMYENILHKPLVLRPGISLTAWSILEELLEKDRQSRLGAKEDFLEIQKHPFFESLSWTD
LLQKKIPPPFNPNVVGPDDIGNFDAVFTEEMVPYSVCISSDYSIVNASVLEADDAFVGFS
YAPPSEDMFS

>Anolis carolinensis_SGK3(ENSACAP_16283)
MDLKESCPSVSIPSSDEHRVKKKRFTVYKVLVSVGTNEWFVFRRYAEFDKLYHTLRKQFP
TMNLRIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVQQPELCNHPDVRSFLQMDNPKHQY
DPSEDEDERNSQKLNSISQNINLGPSGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGK
FYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGG
ELFFHLQKERSFPEHRARFYAAEIASALGYLHSVKIVYRDLKPENILLDSLGHVVLTDFG
LCKEGMATSDTTATFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDV
AEMYENILHKPLHLRPGISLTAWSILEELLEKDRQNRLGAKEDFLEIQSHPFFESLNWTD
LLQKKIPPPFNPNVSGPDDIRNFDTAFTEEMVPYSVCISSDYNIVNASVLEADDAFIGFS
YAPPSEDLFH

>Danio rerio_SGK3(ENSDARP_84801)
MEEQPSCPNVSIPCYNEQRDKKKRYTVYKVMVSVGRHEWFVFRRYAEFDKLYNTLKKQFP
ALNLKIPAKRIFGDNFDPEFIKQRRAGLHEFIQRIVSHSQLCSHPDVKVFLQMDKAKNFS
DGSEDEDDKSNSTSRNINLGPSANPHAKPTDFDFLKVIGKGSFGKVLLAKRKRDGKCYAI
KVLQKKVILNRREQKHIMAERNVLLKNVKHPFLVGLHYSFQTTDKLYFVLDFVNGGELFF
HLQKERTFPEPRAKFYIAEMASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKE
GISQADTTTTFCGTPEYLAPEVLRKQPYDNTVDWWCLGSVLYEMLYGLPPFYSRDTHEMY
DNILHKELVMRPGASTAAWSILQTLLEKDHTRRLGYRDDFNEVKEHEFFSSINWYDLEQK
KLSPPFNPSVESQYDISNFDPEFTEETVPNSVCFSSGPSIVNASVMEADDAFLGFSYAPP
SEDSFL

>Takifugu rubripes_SGK3(ENSTRUP_22790)
TPAAATMEEQPSLPNVSIPCHDEQRDKKKRYTVYKVLVSVGQQEWFVFRRYAEFDKLYNA
LRKQFPSMNLKIPAKRIFGDNFEPEFIKQRRAGLHEFIKKIVSHPQLCNHPDVRAFLQMD
KIRNFSDASEDEDEKVRRFPNNNSTSGNINLGPSANPQAKPTDFDFLKVIGKGSFGKVFL
AKRKTDGKNYAVKVLQKKVILNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTDKLYF
VLDFINGGELFFHLQKERTFPEPRAKFYIAEMASALGYLHSLNIVYRDLKPENILLDHEG
HIVLTDFGLCKEGISQSDTTSTFCGTPEYLAPEVLRKQPYDNTVDWWCLGSVLYEMLFGL
PPFYSRDTHEMYDNILHKPLGMRPGASNTAWSLLQGLLEKDGTHRLGSINDFEEIKAHSF
FYSINWDDLVQKKIPPPFTPKVNSFSDISNFDPEFTEEMVPKSVCWSQEHSIVNASVMEA
DDAFVGFSYAPPSEDSFL

>Tetraodon nigroviridis_SGK3(ENSTNIP_13003)
MPAPAIMEEQPGLPNVSIPCHDEQRDKKKRYTVYKVLVSVGQQEWFVFRRYAEFDKLYNT
LRKQFPSVNLKIPAKRIFGDNFEPEFIKQRRAGLHEFIKKIVSHPQLCNHPDVRAFLQMN
KIRNFSDGSEDEDEKNNSTSGNINLGPSANPQAKPTDFDFLKVIGKGSFGKVFLAKRKID
GKYYAIKVLQKKVILNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQSTDKLYFVLDFIN
GGELFFHLQKERTFPEPRAKFYIAEMASALGYLHSLNIVYRDLKPENILLDHEGHIVLTD
FGLCKEGISQSDTTSTFCGTPEYLAPEVLRKQPYDNTVDWWCLGSVLYEMLFGLPPFYSR
DTHEMYDNILHKPLAMRAGASSTAWSLLQGLLEKDGTHRLGSRNDFDEIKVHNFFSSINW
DDLVQKKIPPPFTPKVNSFSDISNFDPEFTEEMVPKSVCWSQDHSIVNASVMEADDAFLG
FSYAPPSEDSFL

>Gasterosteusaculeatus_SGK3(ENSGACP_3870)
MPTKMEEQTGQPNVSIPCHNEQRDKKKRYTVYKVIVNVGQQEWFVFRRYAEFDKLYNTLR
KQFASTNLKIPAKRIFGDNFDPEFIKQRRAGLHEFIKRIVSDPQLCNQPDVRAFLLMDKM
QSFSDASEDEDDKNSSTSRNINLGPSGNPQAKPTDFDFLKVIGKGSFGKVFLAKLKHDEK
YYAVKVLQKKVILNRKEQKHIMAERNVLLKNVKHPFLVGLQYSFQTTDKLYFVLDFVNGG
ELFFHLQKERTFPEPRAKFYIAEIASALGYLHSLNIVYRDLKPENILLDHEGHIILTDFG
LCKEGISQTDTTTTFCGTPEYLAPEVLRKQPYDNTVDWWCLGSVLYEMLYGLPPFYSRDT
HQMYDNILHKPLVMRPGASSTAWSLLQGLLEKEGMHRLGSMDDFNEIKAHSFFFSINWDD
LEQKKIPPPFTPNVSSYCDISNFDPEFTEEMVPNSICWSKDHSVVNASVMEADDAFVGFS
YAPASDDFFL

>Oryzias latipes_SGK3(ENSORLP_10627)
MLSHAEMEERSSLPSVSIPCHNEQRDKKKRYTVYKVLVSVGQHEWFVFRRYAEFDKLYNT
LRKQFPSMNLKIPAKRIFGDNFDPEFIQQRRAGLHEFIKRLVSHPQLCNHPDVKSFLQMD
KRQHLADASEDEDDKNSSTSRDINLGPSGNPQAKPTDFDFLKVIGKGSFGKVFLAKRKHD
GKFYAIKVLQKKVILNRKEQKHIMAERNVLVKNVKHPFLVGLHYSFQTTDKLYFVLDFVN
GGELFFHLQKERTFPEPRARFYIAEMASALGYLHSLKIVYRDLKPENILLDHEGHIVLTD
FGLCKEGISQTDTTTTFCGTPEYLAPEVLKKHPYDNTVDWWCLGSVLYEMLFGLPPFYSR
DTHEMYDNILHKPLAMRPGASSTAWSLLQGLLEKDGTQRLGSNGDFVCFQNEIKVHNFFS
SINWDDLVQKKIPPPFIPNVTSCCDISNFDPEFTEENVPNSICWTQSHSVVNASVMEADD
AFLGFSYAPPSDDSFL

>Homo sapiens_GRK5(ENSP_376609)
MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHISQCEDLRRTIDRDYCSLCDKQ
PIGRLLFRQFCETRPGLECYIQFLDSVAEYEVTPDEKLGEKGKEIMTKYLTPKSPVFIAQ
VGQDLVSQTEEKLLQKPCKELFSACAQSVHEYLRGEPFHEYLDSMFFDRFLQWKWLERQP
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEK
VNSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLE
DLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQ
RYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSHKFSEEAKSIC
KMLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDVLDI
EQFSTVKGVNLDHTDDDFYSKFSTGSVSIPWQNEMIETECFKELNVFGPNGTLPPDLNRN
HPPEPPKKGLLQRLFKRQHQNNSKSSPSSKTSFNHHINSNHVSSNSTGSS

>Mus musculus_GRK5(ENSMUSP_3313)
MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHISQCEDLRRTIDRDYYSLCDKQ
PIGRLLFRQFCETRPGLECYIQFLDLVAEYEITPDENLGAKGKEIMTKYLTPKSPVFIAQ
VGQDLVSQTEKKLLQSPCKELFSACAQSVHDYLKGDPFHEYLDSMYFDRFLQWKWLERQP
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEK
VNSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLE
DLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQ
RYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSSKFSEEAKSIC
NMLLTKDSKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDVLDI
EQFSTVKGVNLDHTDDDFYSKFSTGSVPIPWQNEMIETECFKELNVFGPNGTLSPDLNRS
QPPEPPKKGLFHRLFRRQHQSNSKSSPTPKTSCNHRINSNHINSNSTGSS

>Rattus norvegicus_GRK5(ENSRNOP_15687)
MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHISQCEDLRRTIDRDYYSLCDKQ
PIGRLLFRQFCETRPGLECYIQFLDLVAEYEITPDENLGAKGKEIMTKYLSPKSPVFIAQ
VGQDLVSQTEKKLLQSPCKELFSACAQSVHDYLKGDPFHEYLDSMYFDRFLQWKWLERQP
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEK
VNSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLE
DLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQ
RYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSPKFSEEAKSIC
NMLLTKDSKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDVLDI
EQFSTVKGVNLDHTDDDFYSKFSTGSVPIPWQNEMIETECFKELNVFGPNGTLSPDLNRS
QPPEPPKKGLFHRLFRRQHQNNSKSSPTPKTSCNHRINSNHINSNSTGSS

>Gallus gallus_GRK5(ENSGALP_15299)
MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHISQCEDLRKTIERDYCSICEKQ
PIGRLLFRQFCETRPELECCIRFLDSVAEYEIAPDEKLGEKGKEIMMKYLTPESPTYVPE
VSQDLIQQTEENLENSPCKELFSHCTKSVLDHLSGEPFQEYLNSMYFDRFLQWKWLERQP
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEK
VNSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLE
DLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGESIRGRVGTVGYMAPEVLNNQ
RYTLSPDYWGLGCLIYEMIAGQSPFRGRKEKVKREEVDRRVLETEEVYSHKFSEEAKSIC
KMLLTKDVKQRLGCQGEGATEVKRHPFFKSMNFKRLEAGMLDPPFVPDPRAVYCKDVLDI
EQFSTVKGVNLDQTDDDFYSKFSTGSVSIPWQNEMIETECFKELNVFGPNGTISPDLNKS
YPPEPPKKGLLQRIFKRQHQNNSKSSSNSKASLNHHINSNHEERQLTEELHSS

>Anolis carolinensis_GRK5(ENSACAP_16696)
MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHISQCEDLRKTIERDYYSLCDKQ
PIGRLLFRQFCETRPELDCCIRFLDSVAEYEITPDAKLGEKGKEIVMKYLIPESPTFVAE
VNQDLVLQTEEILENSPCKELFSPCVKSVREYLSGEPFQEYSESMYFDRFLQWKWLERQP
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEK
VNSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLE
DLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGESIRGRVGTVGYMAPEVLNNQ
RYTLSPDYWGLGCLIYEMIAGQSPFRGRKEKVKREEVDRRVLETEEVYSHKFTEEAKSIC
KMLLTKDVKQRLGCHEEGAVEVKKHPFFKNMNFKRLEAGMLDPPFVPDPRAVYCKDVLDI
EQFSTVKGVNLDQTDDDFYSKFSTGSVSIPWQNEMIETECFKELNVFGPNGTISPDLNKS
FPPEPPKKGLLHRIFKRQHQNNSKSSPNAKANLNHHINANHVSSNSTGSS

>Xenopus tropicalis_GRK5(ENSXETP_22557)
GGGGKRKGKSKKWKEILKFPHISQCEELRRATERDYYNLCEKQPIGRLLFRQFCEAQPDL
ECLIHFLDAVAEYEVTPDEKLGEKGKEIILKYLTPESPVYVSEVGQDIVHQMEEKLEISP
YKELFSHCAKSVSDFLSGEPFHCYLESMYFDRFLQWKWLERQPVTKNTFRQYRVLGKGGF
GEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEKVTSRFVVNLAYAYETKD
ALCLVLTLMNGGDLKFHIYNMGNPGFQEERASFYAAEILCGLGDLHRESIVYRDLKPENI
LLDDYGHIRISDLGLAVKIPEGDSIRGRVGTVGYMAPEVLNNQKYTFSPDFWGLGCLIYE
MIAGQSPFRGRKEKVKREEVDRRVLETEEVYTQKFSEEAKSVCKLLLTKEVKRRLGCQEG
GAVDVKRHPFFRVINFKRLEAGIMDPPFVPDPRAVYCKDVLDIEQFSTVKGVNLDQTDDD
FYTKFSTGSVSIPWQNEMTETECFKELNVYGPNRTLSPDLNRSHPPEPPKKSLLHRIFKR
QHQNNSNSSPCTKSSLNHDVNTNHISTNSTGSS

>Danio rerio_GRK5(ENSDARP_114075)
MELENIVANTVLLKAREGGGGKRKGRSKKWREILRFPHISQCTELNKAIERDYVCLCERQ
PIGRLLFRLYCETQPELQRCIQLLDAMDDYEVSPDEKRKSRGDEIIKKFLNKQSSECVDV
AESLAERCKENLELSPCKEIFSDCRKALHDYLSGAPFTDYQNSMYFDRFLQWKMLERQPI
TKDTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKV
NSRFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNMGTPGFEKERVQLYAAEICCGLED
LHRESIIYRDLKPENILLDDNGHIRISDLGLAIKVPDGEQIRGRVGTVGYMAPEVINNER
YSMSPDWWGLGCLIYEMTAGRSPFRARKERVKREDVEKRVQEEEEEYSDKFSEDTKAICR
MLLSKDPKQRLGCQTDRASGVKAHPFFKNINFKRLEAGILEPSFVPDPRAVYCKDVLDIE
QFSTVKGVNLDQTDNDFYSKFATGSVSIPWQNEMIETECFNDLNVFGPQGTRPPDLDWNQ
PPEPPRRSLLDRIFRRHVRISSTSTTEEHPREQSS

>Gasterosteusaculeatus_GRK5(ENSGACP_15571)
MELENIVANTVLLKAREGGGGKRKGRSKKWKEILRFPHISQCTEQGNSIAERDYVSICEK
QPIGRLLFRLYCDTRPELQRCIHLLDALEDYEVTPDEKRKCRGDQIIKTFLSKQSPQRVD
IAEVFAEQCRENLELSPCKEIFSNCHKTRTVHDYLSEGPFLDYQNSMYFDRFLQWKMLER
QPITKDTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGESMALNEKLIL
EKVNSRFVVSLAYAYETKDALCLVLTIMNGGDLKFHTYNMGTPGFEKDRVQFYAAQICCG
LEHLHRESIVYRDLKPENILLDDNGHIRISDLGLAIKVPDGELIRGRVGTVGYMAPEVIN
NEKYGMSPDWWGLGCLVYEMTAGRSPFRARKERVKYSDKFTADTKAICRMLMTKDPKQRL
GCLEDGAAGVKAHPFFKNINFRRLEAGIVEPPFVPDPRAVYCKDVLDIEQFSTVKGVNLD
QTDNDFYSKFTIGSVSIPWQNEMIETECFRDLNVFGPQGTRPPDLDWDQPPEPPRRSLLD
RIFRRHHPEVSISHSRVQSSSVNSVD

>Oryzias latipes_GRK5(ENSORLP_15874)
ILLQYFYLHVSFLTAGGGGKRKGRSKKWKEILRFPHISQCVELEKIIEKDYDSICEKQPI
GRLLFRMYCDTKPSLQRCIHLLDAMEDYEVSPDENRKSRGEEIIKSFLSKLMKSPQKVDI
AEGFAEQCRKNLELSPCKEIFSTCLKTRAVHDYLSGVPFSDFQKSMYFDRFLQWKMLERQ
PITKDTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILE
KVNSRFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNMGTPGFEKNRVQFYAAQICCGL
THLHRESIVYRDLKPENILLDDNGHIRISDLGLAIKVPEGELIRGRVGTVGYMAPEVINN
EKYAMSPDWWGLGCLIYEMTAGRSPFRARKERVKREEVERRVQEEEEEYNDKFTEDAKAI
CRMLLTKDPKQRLGCKSDGAEGVKAHSFFKSINFKRMEAGIVDPPFFPDPRAVYCKDVLD
IEQFSTVKGVNLDQTDNDFYSKFATGSVSIPWQNEMIETECFRDLNVFGPQGTRPPDLDW
NQPPEPPRRSLLDRIFRRHLSSNSLQHPEVSISNSRVQSSSVNSVDSMSN

>Homo sapiens_AKT3(ENSP_263826)
MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKA_SGKYYAMKILK
KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
RVFSEDRTRFYGAEIVSALDYLH_SGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
PFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE

>Mus musculus_AKT3(ENSMUSP_106789)
MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKA_SGKYYAMKILK
KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
RVFSEDRTRFYGAEIVSALDYLH_SGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
PFKPQVTSETDTRYFDEEFTAQTITITPPEKYDDDGMDGMDNERRPHFPQFSYSASGRE

>Rattus norvegicus_AKT3(ENSRNOP_54688)
MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKA_SGKYYAMKILK
KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
RVFSEDRTRFYGAEIVSALDYLH_SGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
PFKPQVTSETDTRYFDEEFTAQTITITPPEKYDDDGMDCMDNERRPHFPQFSYSASGRE

>Gallus gallus_AKT3(ENSGALP_31235)
MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKA_SGKYYAMKILK
KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
RVFSEDRTRFYGAEIVSALDYLH_SGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
EDIKFPRTLSADAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFAGVNWQDVYDKKLVP
PFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE

>Danio rerio_AKT3(ENSDARP_111940)
MNDLNVVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDADLAYPLNNFSVAKCQ
LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEESRDEWVEAIQMVADKLAKQEEEGILC
SPISQIENVNEEEMDTSTSHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGTYYAMKIL
KKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSR
ERVFSEDRTRFYGAEIVSALDYLHSAKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITD
AATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELIL
MEEIKFPRTLSADAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFTALDWQDVYDKKLV
PPFMPQVSSETDTRYFDEEFTAQTITITPPEKYDEDGMDAADSERRPHFPQFSYSASGRE

>Takifugu rubripes_AKT3a(ENSTRUP_1808)
IYASSHLKSSSLGEYIKNWRPRYFLLKTDGSFIGYKEKPQDADLPYPLNNFSVAKCQLMK
TERPKPNTFIIRCLQWTTVIERTFHVDSPDERDEWTEAIQMVADKLQRQEEERIQCSPTS
NIDNMVEEEMDISTTHHKRKVTTMSDFDYLKLLGKGTFGKVILVREKA_SGKYYAMKILKK
EVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRER
VFSEERTRFYGAEIVSALDYLHSAKIVYRDLKLENLMLDKDGHMKITDFGLCKEGITDAA
TMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVTYEMMCGRLPFYNQDHEKLFELILME
DIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGIDWQDVYDKKLVPP
FKPQVTSETDTRYFDEEFTAQTITITPPEKFDEDGMDCLDNERRPHFPQFSYSASGRE

>Takifugu rubripes_AKT3b(ENSTRUP_8516)
MSDQNVVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKDKPQDSDLAYPLNNFSVAKCQ
LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPDERDEWAEAIQMVADSLAKQEEEGILCS
PISQIENVNEEEMDTSISHYKRKFVQTMNDFDYLKLLGKGTFGKVILVKEKASGTYYAMK
ILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHL
SRERVFSEDRTRFYGAEIVSALDYLHSAKIVYRDLKLENLMLDKDGHIKITDFGLCKEGI
TDTATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
ILMEEIKFPRTLSADAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSTIDWQDLYDKK
LVPPFQPQVSSETDTRYFDEEFTAQTITITPPEKYDEDGMDAADNERRPHFPQFSYSASG
RE

>Tetraodon nigroviridis_AKT3(ENSTNIP_7984)
MSDQNVVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKDKPQDSDLAYPLNNFSVAKCQ
LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPDERDEWAEAIQMVADSLAKQEEEGILSS
PTSQIENVNEEEMDTSISHYKRKVQTMNDFDYLKLLGKGTFGKVILVKEKASGTYYAMKI
LKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTDRLCFVMEYVNGGELFFHLSR
ERVFSEDRTRFYGAEIVSALDYLHSAKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITD
TATMKTFCGTPEYLAPERQVLEDNDYGRGVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
ILMEEIKFPRTLSADAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSTIDWQDLYDKK
LVPPFQPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDAADNERRPHFPQFSYSASG
RE

>Gasterosteusaculeatus_AKT3a(ENSGACP_13936)
GEYIKNWRPRYFLLKTDGSFIGYKEKPQDADLPYPLNNFSVAKCQLMKTERPKPNTFIIR
CLQWTTVIERTFHVDSPDERDEWTEAIQMVADKLQRQEEERFQCSPTSNIDNMVEEEMDI
STTHHKRKTMSDFDYLKLLGKGTFGKVILVREKA_SGKYYAMKILKKEVIIAKDEVAHTLT
ESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEERTRFYGAEI
VSALDYLHSAKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAP
EVLEDNDYGRAVDWWGLGVVTYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKS
LLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVDWQYVYDKKMVPPFRPQVTSETDTRYF
DEEFTAQTITITPPEKFDEDGMDCLDNERRPHFPQFSYSASGRE

>Gasterosteusaculeatus_AKT3b(ENSGACP_26103)
MSDQNVIKEGWVQKRGEYIKNWRPGYFLLKTDGSFIGYKDKPQDSDLAYPLNNFSVDKCE
HDENRAFQYQTPSPSGAWGEPPVIERTLHVDTHEEEEDEWAEAIQMVAESLAKQEEEGIL
SSPTSQIENVNEEEMDTSIGHYKRKTMTDFDYLKLLGKGTFGKVILVREKASGTYYAMKI
LKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLS
RERVFSEDRTRFYGAEIVSALDYLHSAKIVYRDLKLENLMLDKDGHIKITDFGLCKEGIT
DTATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVTYEMMCGRLPFYNQDHEKLFELI
LMEEIKFPRTLSADAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFNAVDWQDVYDKKL
VPPFQPQVSSETDTRYFDEEFTAQTITITPPEKYDEDGMDAADNERRPHFPQFSYSASGR
E
>Oryzias latipes_AKT3a(ENSORLP_6058)
CDELTCLCQIGLVFTGEYIKNWRPRYFLLKTDGSFIGYKEKPQDADLPYPLNNFSVAKCQ
LMKTERPKPNTFIIRCLQWTTVIERTFHVDSPDERDEWTEAIQMVADKLQRQEEERIQCS
PTSNIDNMVEEEMDISTTHHKRKQTMSDFDYLKLLGKGTFGKVILVREKA_SGKYYAMKIL
KKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSR
ERVFSEDRTRFYGAEIVSALNYLHSAKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITD
AATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVTYEMMCGRLPFYNQDHEKLFELIL
MEEIKFPRTLSADAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVDWQDVYDKKLV
PPFKPQVTSETDTRYFDEEFTAQTITITPPEKFDEDGMDCLDNERRPHFPQFSYSASGRE

>Oryzias latipes_AKT3b(ENSORLP_1785)
MSDQNVVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKDKPQDSDLAYPLNNFSVAKCQ
LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPDERDEWAEAIQMVAESLAKQEEEGILCS
PTSQIENVNEEEMDTSISHYKRKKNKTMNDFDYLKLLGKGTFGKVILVREKASGTYYAMK
ILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHL
SRERVFSEDRTRFYGAEIVSALDYLHSAKIVYRDLKLENLMLDKDGHIKITDFGLCKEGI
TDTATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVTYEMMCGRLPFYNQDHEKLFEL
ILMEEIKFPRTLSADAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSTIDWQDVYDKK
LVPPFQPQVSSETDTRYFDEEFTAQTITITPPEKYDEDGMDAADNERRPHFPQFSYSASG
RE

>Homo sapiens_GRK7(ENSP_264952)
MVDMGALDNLIANTAYLQARKPSDCDSKELQRRRRSLALPGLQGCAELRQKLSLNFHSLC
EQQPIGRRLFRDFLATVPTFRKAATFLEDVQNWELAEEGPTKDSALQGLVATCASAPAPG
NPQPFLSQAVATKCQAATTEEERVAAVTLAKAEAMAFLQEQPFKDFVTSAFYDKFLQWKL
FEMQPVSDKYFTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALLEK
EILEKVSSPFIVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTRGLDMSRVIFYSAQI
ACGMLHLHELGIVYRDMKPENVLLDDLGNCRLSDLGLAVEMKGGKPITQRAGTNGYMAPE
ILMEKVSYSYPVDWFAMGCSIYEMVAGRTPFKDYKEKVSKEDLKQRTLQDEVKFQHDNFT
EEAKDICRLFLAKKPEQRLGSREKSDDPRKHHFFKTINFPRLEAGLIEPPFVPDPSVVYA
KDIAEIDDFSEVRGVEFDDKDKQFFKNFATGAVPIAWQEEIIETGLFEELNDPNRPTGCE
EGNSSKSGVCLLL

>Gallus gallus_GRK7(ENSGALP_4421)
MSSDLVSKCQAATEKDYENVVQLARDEAKVFLQGKPFQDFQTSPFYDKFLQWKVFEKQPV
TDKYFYEFRVLGKGGFGEVCAIQVKNTGKMYACKKLDKKRLKKKCGEKMALLEKEILEKV
NSPFIVTLAYAYESKTHLCLVMSLMNGGDLKYHIYNVGQRGLELNRVIYYSAQITCGILH
LHSIKIIYRDMKPENVLLDDNGNCRLSDLGLAVQVKEGKSITQRAGTNGYMAPEILKEES
YSYPVDWFAMGCSIYEMIAGRTPFKNFKEKVDKDEVKRRTLEDEVKFEHANFTEETKDIC
RLFLAKKPENRLGSSEDDDPRKHSFFKTINFHRLEANLIDPPFVPDPSVVYAKDVADIAD
FSEIRGIEFDDKDKKFFKKFATGAVSIPWQEEIIETGLFEELN

>Anolis carolinensis_GRK7(ENSACAP_5000)
LDNLIANTAYLNARKSGDVDAKELQKRWRVLALPKIEECAAIKESITMDYNAICEQQPVG
KKFFGEFLETVPEYLVAKEFMDEVYAWELAEDNVKNSLLEGIINMYLKNVSNSFLKFLSA
DLSNKCQSVSKDDFEKIVLSAREETNEYLKGKPFQDFQTSPFFDKFVQWKGFEKQPVNEK
LFDEFRVLGKGGFGEVCAIQARNTGKMYACKKLDKKRLKKKGGEKMALLEKEILEKVNSR
FIVTLSYAYQSKAALCLVMSLMNGGDLKYHIYNVGERGLEMNRVIFYSAQITCGILHLHS
IQIVYRDMKPENVLLDDNGHCRLSDLGLAVEVKEGKEIRQRAGTNGYMAPEILNEEAYTY
PVDWFAMGCSIYEMIAGRTPFKDFKEKVNKDEVKKRTLEDDPKYEHKDFDEPTKNICNLF
LAKKPENRLDCMQSNDDDPRKHPFFKSINFHRLEAGLIDPPFVPDPSVVYAKDVADIADF
SEVRGIEFDDKDKKFFKKFATGAVPIPWQEEVIETGLFDELN

>Xenopus tropicalis_GRK7(ENSXETP_32324 )
MCDMGGLDNLIANTAYLQARKNSEGDAKELQKRRKSLSLPPPDVSRKEIKETITLDYQSI
CVEQPIGQRLFKDFLATVPEYKLAEEFLEEVKDWELEEGSAKEQLMEKLVSRRFKEPAEG
SLNFLGKDLSSRIQKGQSKDMPELIMLAKEAGTAFLMDAPFQDYQNSSFYDRFLQWKAFE
RQQITQKYFYEFRILGKGGFGEVCAIQVKNTGQMYACKKLDKKRLKKKNGEKMALLEKEI
LEKVHSPFIVSLAYAYETKSHLCLVMSLMNGGDLKFHIYNVGEKGIEMKRVIFYSAQICC
GILHLHSLKIVYRDMKPENVLLDENGNCRLSDLGLAVKVKEGKPITQRAGTNGYMAPEIL
TDEDYSYPVDWFAMGCSIYEMVAAHTPFRDPKDKTSKEELKRRTLEDEVGFQHQNFTEEA
KDICRLFLAKKPQNRLGSRTNDDDPRKHSFFKSINFQRLEAGMVDPPFVPDPSVVYAKDI
SDIADFSEIKGIEFDDKDAKFFKRFATGAVPISWQKEIIDTGLFDELNDPSREASGGGGN
SGEKSGVCSIL

>Danio rerio_GRK7a(ENSDARP_91060)
MCDMGGLDNLVANTAYLKAQGGDDKEMKKRRRSLSLPKPEQCASLRTSLDKDFESLCEKQ
PIGKKLFRQYLSQGGPECTTAAEFLDDLNEWELSESAARDKARTNIINKFCKEGSKSSLT
FLTGDVATKCKAVSDKDFEEVMGQVKTATKEFLKGKPFTEYQASPFFDKFLQWKEYEKQP
ISEKYFYEFRTLGKGGFGEVCAVQVKNTGQMYACKKLCKKRLKKKHGEKMALLEKKILER
VNSLFIVSLAYAYDTKTHLCLVMSLMNGGDLKYHIYNIGEKGIEMDRIIYYTAQIATGIL
HLHDMDIVYRDMKPENVLLDSQGQCRLSDLGLAVEIAVGKTISQKAGTGAYMAPEILNET
PYRTSVDWWALGCSIYEMVAGYTPFKGPDAKKEKVEKEEVQRRILNEEPKFEHKNFDAAT
IDIIKQFLKKKIDERLGCKNDDPRKHEWFKSINFARLEAGLIDPPWVPKPNVVYAKDTGD
IAEFSEIKGIEFDAKDDKFFKEFSTGAVSIAWQQEMIDTGLFDELSDPNRKESSGGSDDD
KKSGTCTLL

>Danio rerio_GRK7b(ENSDARP_72364)
MSDMGGLKNLVANTDYLKAQSLDEKEIKKRRCSLGLPHLGNCTDVRVSVSKGFEDICEQQ
PIGRACFRQFLSVSSPEYLAAAELLDELNCWNLAEAEAKEEARLNIINKFCKADSKSFLA
FLTEDEAEKCKAVSEKDFEEVMMGQVKEATQKFLRGQPFEEYQTSLFFDRFVQWKKFEKQ
PITDKYFYEFRTLGKGGFGEVCGVQVKTTGQMYACKKLDKKRLKKKSGEKMALLEKKILE
MVNSLFIVNLAYAFDTKTHLCLVMTLMSGGDLKYHIFHVGEVGIEMERIIHYTAQITSGI
LHLHSMDIVYRDMKPENVLLDCQGQCRLSDLGLAVELPNGKTTTQKAGTKGYMAPEILKQ
EPYRTSVDWWALGCSIYEMVAGRVPFRDHKEKVAKEELLRRTLEDEVKFEHRNFDAPSKD
IISLFLKRNIEDRLGSNDDPRKHEFFKSINFPRLEAGLIPPPWEPKANVVYAKDTGDIRE
FSDVKGVKFDANDEKFFKEFSTGVVPIAWQQEMIDSGLFDELSDPNRKESAAGLEDEEQQ
KSKSCTLL

>Takifugu rubripes_GRK7a(ENSTRUP_1673)
MCDMGGLDNLVANTAYLKAQGGDDKEMKKRRRSLSLPKPDQCAAARTAIEKDFTSICERQ
PIGKKFFRDFLATKAEYKVAADFLDDLYDWDLAEQAAKTKACQNIMQTYCKADSKKFLSF
LSGEAAEKCKGVTEGNFEEVMKGKVQDGVREFLKDKPFTEFQTSPFFDKFLQWKEYEKQP
ISDKYFYEFRTLGKGGFGEVCAVQVKNTGQMYACKKLCKKRLKKKGGEKMALLEKKILEK
VNSLFLVNLAYAYHTKDSLCLVMTLMNGGDLKYHIYNIGYDGKGVDKGIEMKRVVHYTAQ
ITTGILHLHEMDIVYRDMKPENVLLDSQGQCRLSDLGLAIEIA_SGKTVTQMAGTGAYMAP
ELLSKTPYRTSVDWWALGCSIYEMVAGYTPFKGPESKKEKVEKEEVQRRILNEEPKWEHK
FFDAVTKDIIQQFLKKKIEERLGMKNNLEDPRKHEWFKSISFPRLEAGLVDPPWTPKPNV
VYAKDTGDIAEFSEIKGIEFDAKDDKFFKDFSTGAVAIAWQQEMIDTGLFDELNDPNRKE
GGGDPDDGKKSGTCIVL

>Takifugu rubripes_GRK7b(ENSTRUP_15027)
YESLCEQQPIGRRLFRQFLLDSNSQYAAAAKLLEDFDYWQHMEDEAKEKAKMSVLAKFCQ
PESRTFLFSHAGDAAEKYASLSISNFDEAAMEHVREATRTFLKGGPFSEYLKSPFFYRFL
QWKEYEKQKITRKYFYEFRTLGRGGFGEVCAVQVKHTGQMYACKKLDKRRLKTKGGERLA
LIEKQILEKANSRFVINLAYAYEDRTHLCLVIDLMSGGDLKFHIYDLGKRGIRMERVVYY
VAQITSGILHLHSMDIVYRDMKPENVLLDAKGQCRLSDFGLAVELPKGKKICQKAGTTGY
MAPEILRQENYGMSVDWWSVGCSIYEMVAARLPFKDFKEKVQNEEVTRRTLEDDCKFQHS
DFDAPVKDLISHFLKKKVQNRLGCRSSGDDPRNHVFFKGINFHRLEAGLAEPPWVPKPNV
IYAKDMDAFRTASEVEDVKLDSKDERFFKEFSTGAVPVRWQKEMIESGTFDLLNSFNGTL
PPHLRTNMSP

>Tetraodon nigroviridis_GRK7(ENSTNIP_10662)
MCDMGGLDNLVANTAYLKAQGGDDKEMKKRRRSLALPKTEQCAAVRASVEKDFSSVCERQ
PIGKRFFRDFLATKAEYKVAADFLDDLYDWDLAEQAAKNKARQNIMQNYCKADSKKFLSF
LSGEIAEKCKGVTEANFEEVMKGKVQDGVREFLKGKPFTEFQTSLFFDKFLQWKEYEKQP
INDKYFYEFRTLGKGGFGEVCAVQVKNTGQMYACKKLCKKRLKKKGGEKMALLEKKILEK
VNSLFLVNLAYAYHTKEHLCLVMTLMNGGDLKYHIYNIGYDGKGVDKGIEMKRVIHYTAQ
ITTGILHLHQMDIVYRDMKPENVLLDSQGQCRLSDLGLAIEIVPGKTVTQMAGTGAYMAP
EILSKTPYRTSVDWWALGCSIYEMVAGYTPFKGPESKKEKVEKEEVQRRILNEEPKWEHK
FFDAATKDIIQQFLKKKIEERLGMKNNMEDPRKHEWFKTISFPRLEAGLVDPPWTPKPNV
VYAKDTGDIAEFSEIKGIEFDAKDEKFFKDFGTGAVPIAWQQEMIDTGLFDELNDPNRKE
GSGDPDGEKKSGTCILL

>Gasterosteusaculeatus_GRK7a(ENSGACP_20785)
MCDMGGLDNLVANTAYLKAQGGDDKEMKKRRRSLALPKTEQCAAVRASLEKDFTSLCERQ
PIGKRFFRDFLANNPDYKLAVDFLDELYDWDLAEGAEKEKAKKSIMSKYCNADSKTFLSF
LTGEPLEKCKAVTDANFDEVMKSKVQEGVRDYLKDKPFSDYQASPFFDKFLQWKEYEKQT
ITDKYFYEFRTLGKGGFGEVCAVQVKNTGQMYACKKLCKKRLKKKGGEKMALLEKQILEK
VNSLFLVNLGYAYDTKTHLCLTMTLMNGGDLRYHIYNIGYDGKGADKGIEMSRIIHYTAQ
ITTGILHLHEMNIVYRDMKPENVLLDSFGQCRLSDLGLAIELVPGKHVTQMAGTGAYMAP
ELLTKTPYRTSVDWWALGCSIYEMVAGYTPFKGPESKKEKVEKKERSQRRPQIENPSGST
SALDIIQQFLRKKIEERLGMKNNMEDPRKHEWFKKINFPRLEAGLVDPPWVPKPNVVYAK
DTDDIAEFSEIKGIEFDANDNKFFKEFSTGAVPIQWQQEMIETGLFDELNDPNRKEGGGD
ADGDKKSGTCILL

>Gasterosteusaculeatus_GRK7b(ENSGACP_10084)
MGELLGLNSLVANTAYLTAQHTDRDELRKLRPPLTLPKPKMSSALRTAVGRKYESLCERQ
PIGRKLFQQFLRACNPQYRVAAEFLEELSDWCFAEDDAREAAKQRILAKFCQPESGSFLS
YLTGEAAERCKRLSDKDFEMTSDQMREDTTDFLRGKPFSEYLNSPFFYRFLQWKEYEKQK
ISDRYFHEFRTLGRGGFGAVCAVQVKQTGQMYACKKLNKRCLKKESGEEMALVEKQILEK
VNSLFVVNLAYAYDNKTHLCMVMDLMNGGDLGFHIYKLGERGIRMERVVYYVAQITTGLL
HLHSMDIVYRDMKPDNVLLDARGQCRLSDLGLAVELPKGKKVCQKAGTTGYMAPEILRQE
YYRTSVDWWAVGCSIYEMVAARLPFKDFREKVQNEEVTRRTLEDECKFEHKHFDAPTQDL
VRRFLKKKQAHRLGCRNGDDPRNHAFFKSINFRRLEAGLLEPPWTPKPHVVYANDTDTFG
DVSEVEDVKFEAKDEKFYKQFSTGAVPIRWQKEMIDTGVFDELDQPRLNGHSREAAWESR
TCAVL

>Oryzias latipes_GRK7a(ENSORLP_5925)
MCDMGGLDNLVANTAYLKAQGGDDKEMKKRRRSLSLPKPEQCVALRESIEKDFTLLCERQ
PIGKRLFRDFLANTPEFKLAAEFLDELYDWXXXXDLAEGAAKDKARQNIINKYCKPDSKT
FLTFLSGEPAEKCKSVTDATFEEVMKNKVQDGVREFLKGKPFTEYQGSQYFDKFLQWKEY
EKQPISDKYFYEFRTLGKGGFGEVCAVQVKNTGQMYACKKLCKKRLKKKGGEKMALLEKQ
ILEKVNSLFLVNLAYAYDTKTHLCLVMTLMNGGDLKYHIYNIGYDGKGVDKGIEMKRIIH
YTAQITTGILHLHDMDIIYRDMKPENVLLDSQGQCRLSDLGLAIEIAPGKTVTQMAGTGA
YMAPEILSKTPYRTSVDWWALGCSIYEMVAGYTPFKGPESKKEKVEKEEVQRRILNEEPK
WEHKCFDAPTKDVIQQFLKKKIDERLGMRNNMEDPRKHEWFKSINFPRLEAGLVDPPWVP
KPNVVYAKDTGDIAEFSEIKGIEFDAKDDKFFKEFSTGAVPIQWQQEMIETGLFDELNDP
NRKEGAGGGDDEKKSGTCALL

>Oryzias latipes_GRK7b(ENSORLP_14549)
KADPAGLESLVVNTAYLKGQQAGRNEQRMRRESLTLPNPKKSTAPRAGAEKSYEWLCELQ
PIGRKLFLQFLMTSDPQRAAAAVFLQELDDWSFAEDATKEKVRQRILAKFCHPQSQTFLS
YLTEDSNLCRTLSVKSLDEETVQKITNATKDFLKGKPFLEYLKSPHFYRFLQWKECERQK
ITDKYFYEFRTLGRGGFGEVCVVQVKYTGHMYACKKLDKRRLKKKSGERLALQEKQILEK
VNSPFIVNLAYAYESRTHLCLVMDLMSGGDLKFHIYELGERGIRMERVVYYTAQIISGIL
HLHSMDIVYRDMKPENVLLDGKGQCRVSDLGLAVELPNGKMICQRAGTTGYMAPEVLKQE
YYRTSVDWWALGCSIYEMVAARLPFRDFREKVQNTEVTRRTLEDDCKFEDKRFDSPTKEI
IVQFLRKKVAHRLGCRKGDDPRNHSFFKNINFHRLEAGLVEPPWVPKANVVYAKNIEDCR
DNSDVRDVELNCKDEKFFKEFSTGAVPIRWQREIIDSGLFDELNNSQMNGNCHKTVWISR
MCII

>Homo sapiens_SGK1(ENSP_356832)
MVNKDMNGFPVKKCSAFQFFKKRVRRWIKSPMVSVDKHQSPSLKYTGSSMVHIPPGEPDF
ESSLCQTCLGEHAFQRGVLPQENESCSWETQSGCEVREPCNHANILTKPDPRTFWTNDDP
AFMKQRRMGLNDFIQKIANNSYACKHPEVQSILKISQPQEPELMNANPSPPPSPSQQINL
GPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMS
ERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAE
IASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLA
PEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSAR
HLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHF
DPEFTEEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPTDSFL

>Mus musculus_SGK1(ENSMUSP_114074)
MVNKDMNGFPVKKCSAFQFFKKRVRRWIKSPMVSVDKHQSPNLKYTGPAGVHLPPGESDF
EAMCQSCLGDHAFQRGMLPPEESCSWEIQPGCEVKEQCNHANILTKPDPRTFWTNDDAAF
MKQRRMGLNDFIQKIASNTYACKHAEVQSILKMSHPQEPELMNANPSPPPSPSQQINLGP
SSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSER
NVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIA
SALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPE
VLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHL
LEGLLQKDRTKRLGAKDDFMEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDP
EFTEEPVPSSIGRSPDSILVTASVKEAAEAFLGFSYAPPVDSFL

>Rattus norvegicus_SGK1(ENSRNOP_57871)
MGEMQGALARARLESLLRPRHKKRVEAQKRSESVLLSGLAFMKQRRMGLNDFIQKLANNS
YACKHPEVQSYLKISQPQEPELMNANPSPPPSPSQQINLGPSSNPHAKPSDFHFLKVIGK
GSFGKVLLARHKAEEAFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSF
QTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPE
NILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAV
LYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDF
MEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDPEFTEEPVPSSIGRSPDSIL
VTASVKEAAEAFLGFSYAPPMDSFL

>Gallus gallus_SGK1(ENSGALP_31130)
MTVKAAEASGPALTYSKMRGMVAILIAFMKQRRMGLNDFIQKIATNSYACKHPEVQSILK
ISQPQEPELMNANPSPPPSPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKA
EEQFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYI
NGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLT
DFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYS
RNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKEDFTEIKNHIFFSPIN
WDDLINKKITPPFNPNVSGPSDLRHFDPEFTDEPVPNSIGQSPDSILITASVKEAAEAFL
GFSYAPPVDSFL

>Anolis carolinensis_SGK1(ENSACAP_10101)
MVNKDMNGFPVKKCSAFQFFKKRVRRWIKSPMVNMEKHQTSSLKYPGPTVMHIPQGEPDI
EEPLCQMCFSDHTFQRGIVPQDTESCSWEGHRSCNMKELYNKEDLLAQPDQRTFWTNDDS
AFMKQRRMGLNDFIQKIATNSYACKHPEVQSILKISQPQEPELMNANPSPPPSPSQQINL
GPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEQFYAVKVLQKKAILKKKEEKHIMS
ERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAE
IGSALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLA
PEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSAR
HLLEGLLQKDRTKRLGAKEDFMEIKNHIFFSPINWDDLINKKITPPFNPNVSGPSDLRHF
DPEFTEEPVPNSIGQASDSILITASVKEAAEAFLGFSYAPPMDSFL

>Xenopus tropicalis_SGK1(ENSXETP_246)
MTVKTETAAGSNTLTYSKMRGMVALLIAFMKQRRMGLNDFIQKIATNSSYACKHSEVQSI
LNISPPQEPELLNENSSPPPSPSQQINLGPSSNPHAKPSDFQFLKIIGKGSFGKVLLARH
NADEKFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTTSRLYFILD
YINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHII
LTDFGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPF
YSRNTAEMYDNILNKPLQLKPNITNSARNLLEGLLQKDRTKRIGAKNDFMEIKNHMFFSP
INWDDLINKKITPPFNPNVSGPSDLQHFDPEFTEEPVPNSIGQSPDSILITASIKEAAEA
FMGFSYAPPMESYL

>Danio rerio_SGK1(ENSDARP_31762)
MTIQTETSVSAPDLTYSKTRGLVANLSAFMKQRKMGLNDFIQKLSANSYACKHPEVQSIL
NLTPPQDVELMNSNPSPPPSPSQQINLGPSSNPTAKPSDFDFLKVIGKGSFGKVLLARHR
SDEKFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHYSFQTTDKLYFVLDY
INGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIIL
TDFGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFY
SRNTAEMYDNILNKPLQLKPNISNAARHLLEGLLQKDRTKRLGFTDDFTEIKNHMFFSPI
NWDDLNAKKLTPPFNPNVTGPNDLRHFDPEFTDEPVPNSIGCSPDSALVTSSITEATEAF
LGFSYAPAMDSYL

>Takifugu rubripes_SGK1(ENSTRUP_6466)
MTIQTETEKSALTYSKSKGLGTLVSAFMKQRKMGLNDFIQRLATNSYACKHPEVQSILNL
NPPQDAELMNANPSPPPSPSQQINLGPSSNPSAKPNDFHFLKVIGKGSFGKVLLARHRTD
DQFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHYSFQTADKLYFVLDYIN
GGELFYHLQRERCFLEPRARFYSAEIASALGYLHSLNIVYRDLKPENILLDSQGHIILTD
FGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSR
NTAEMYDNILNKPLQLKPNISNAARHLLEGLLQKDRTKRLGCTEDFIEIRNHMFFSPINW
DELNAKKITPPFNPDVTGPNDLRHFDPEFTDEPVPSSIGCSPDSVLVTASIKEAAEAFVG
FSYAPSMDSYL

>Tetraodon nigroviridis_SGK1(ENSTNIP_19416)
MTVQTETEQPALTYSKSKGLVTLVTAFMKQRRMGLNDFIQRLATNSYACKHPEVQSILNL
NPPQDAELMNANPSPPPSPSQQINLGPSSNPSAKPNDFHFLKVIGKGSFGKVLLARHRTD
DQFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHYSFQTADKLYFVLDYIN
GGELFYHLQRERCFLEPRARFYSAEIASALGYLHSLNIVYRDLKPENILLDSQGHIILTD
FGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSR
NTAEMYDNILNKPLQLKPNISNAARHLLEGLLQKDRTKRLGCTEDFIEIKNHMFFSPINW
DDLNAKKITPPFNPNVTGPNDLRHFDPEFTDEPVPSSIGCSPDSVLITASIKEAAEAFVG
FSYAPSMDSYL

>Gasterosteusaculeatus_SGK1(ENSGACP_14552)
LRPPKRSFFASSASRAFMKQRRMGLNDFIQRLATNSYACKHPEVQSILNLSPPQDAELMN
TNPSPPPSPSQQINLGPSSNPSAKPNDFHFLKVIGKGSFGKVLLARHRADDQFYAVKVLQ
KKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHYSFQTADKLYFILDYINGGELFYHLQR
ERCFLEPRARFYSAEIASALGYLHSLNIVYRDLKPENILLDSQGHIILTDFGLCKENIEP
NGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNIL
NKPLQLKPNISNAARHLLEGLLQKDRTKRLGCADDFIEIKSHVFFSPINWDDLNAKKITP
PFNPNVTGPNDLRHFDPEFTDEPVPSSIGCSPDSALVTASIKDAAEAFVGFSYAPSMDSY
L

>Oryzias latipes_SGK1(ENSORLP_20683)
MTVITEAEKPALTYSKTRGLVGLVSAFMKQRRMGLNDFIQRLATNSYACKHPEVQSILNL
SPPQDAELMNVNPSPPSSPSQQINLGPSSNPSAKPSDFHFLKVIGKGSFGKVLLARHRTD
DQFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHYSFQTADKLYFVLDYIN
GGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIILTD
FGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSR
NTAEMYDNILNKPLQLKPNISNSARNLLEGLLQKDRTKRLGCTNDFIEIKNHVFFSPINW
DELNAKKITPPFNPNVTGPNDLRHFDPEFTDEPVSSSIGCSPDSALFTASIKEAAEAFVG
FSYAPSMDSYL

>Homo sapiens_ADRBK1(ENSP_312262)
MADLEAVLADVSYLMAMEKSKATPAARASKKILLPEPSIRSVMQKYLEDRGEVTFEKIFS
QKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLAC
SHPFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNV
ELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER
IMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAE
IILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPE
VLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPE
LRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAA
DAFDIGSFDEEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARK
KAKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSL
LTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQR
VPKMKNKPRSPVVELSKVPLVQRGSANGL

>Mus musculus_ADRBK1(ENSMUSP_86114)
MADLEAVLADVSYLMAMEKSKATPAARASKKILLPEPSIRSVMQKYLEDRGEVTFEKIFS
QKLGYLLFRDFCLNHLEEAKPLVEFYEEIKKYEKLETEEERVVRSREIFDSYIMKELLAC
SHPFSKNATEHVQGHLVKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNV
ELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER
IMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAE
IILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKRPHASVGTHGYMAPE
VLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPE
LRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAA
DAFDIGSFDEEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARK
KAKNKQLGHEEDYALGKDCIVHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSL
LTMEEIQSVEETQIKERKCLLLKIRGGKQFVLQCDSDPELVQWKKELRDAYREAQQLVQR
VPKMKNKPRSPVVELSKVPLIQRGSANGL

>Rattus norvegicus_ADRBK1(ENSRNOP_25847)
SIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLNHLEEAKPLVEFYEEIKKYEKLET
EEERVVRSREIFDSYIMKELLACSHPFSKNATEHVQGHLVKKQVPPDLFQPYIEEICQNL
RGDVFHKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMY
AMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGG
DLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLG
LACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTK
DKHEIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLD
WQMVFLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDSDQELYRNFPLTISERW
QQEVAETVFDTINAETDRLEARKKAKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQ
RRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFVLQCDSD
PELVQWKKELRDAYREAQQLVQRVPKMKNKPRSPVVELSKVPLIQRGSANGL

>Gallus gallus_ADRBK1(ENSGALP_28987)
MADLEAVLADVSYLMAMEKSRAAPAARASKRILLPEPSIRSVMQKYLEDRGEVTFDKIFA
QKIGYLLFRDFALNQAEEAKPLMEFYEEIKKYEKLDSEEERATRSRHIFDHYIMKELLAC
SHPFSKSATEHVQSRLSKKQVPPDLFQPYIEEICQNLRGSIFQKFIESDKFTRFCQWKNV
ELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER
IMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEAEMRFYAAE
IILGLEHMHSRFVVYRDLKPANILLDEFGHVRISDLGLACDFSKKKPHASVGTHGYMAPE
VLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPE
LRSLLEGLLQRDVNQRLGCMGRGAQEVKEEPFFRGLDWQMVFLQKYPPPLIPPRGEVNAA
DAFDIGSFDEEDTKGIKLLESDQELYRNFPLTISERWQQEVTETVFDTVNADTDKQEARK
KAKNKQLGHEEDYAMGKDCIVHGYMSKLGNPFLTQWQRRYFYLFPNRLEWRGEGESPQSL
LTMEEIDSVEETQVKERKCILLRIRGGKQFVLQCDSDPELVQWQKELRDAQRQAQQLLQR
VPRMQNKPRSPVVELSKVPFLQRSANGL

>Homo sapiens_RPS6KB2(ENSP_308413)
MAAVFDLDLETEEGSEGEGEPELSPADACPLAELRAAGLEPVGHYEEVELTETSVNVGPE
RIGPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAER
NILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITL
ALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEI
LVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLV
KKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQFDT
RFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRA
PVSPLKFSPFEGFRPSPSLPEPTELPLPPLLPPPPPSTTAPLPIRPPSGTKKSKRGRGRP
GR

>Mus musculus_RPS6KB2(ENSMUSP_25749)
MAAVFDLDLETEEGSEGEGEPEFSPADVCPLGELRAAGLETVGHYEEVELTESSVNLGPE
RIGPHCFELLSVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVCSAKDTAHTRAER
NILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITL
ALGHLHSHGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAITHTFCGTIEYMAPEI
LVRTGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGKLVLPPYLTPDARDLA
KKFLKRNPTQRIGGGLGDAADVQRHPFFRHINWDDLLARRVDPPFRPSLQSEEDVSQFDA
RFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRT
PISPLKFSPFEGFRPSPGPPEPMEPSLPPLLPSPPSPPPTSTAPLPIRPPSGTKKSKKGR
GRSGR

>Rattus norvegicus_RPS6KB2(ENSRNOP_29993)
MAAVFDLDLETEEGSEGEGEPEFNPADVCPLGELRAAGLETVGHYEEVELTESSVNLGPE
RIGPHCFELLSVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVCSAKDTAHTRAER
NILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITL
ALGHLHSQGIIYRDLKPENIMLNSQGHIKLTDFGLCKESIHEGAITHTFCGTIEYMAPEI
LVRIGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGKLVLPPYLTPDARDLA
KKFLKRNPTHRIGGGPGDAADVQRHPFFRHINWDDLLAHRVDPPFRPSLQSEEDVSQFDV
RFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRT
PISPLKFSPFEGFRPSPGPPEPMEPSLPPLLPPPSSPPPTSTAPLPIRPPSGTKKSKKGR
GRPGR

>Anolis carolinensis_RPS6KB2(ENSACAP_8180)
MAGVFDLDLETEEGSDGEEPELGGLDVDPDLRCSGPDQVPGYYEEIEISENIVNNGPERI
GPHCFELLRVLGKGGYGKVFQVRKVQGTNAGKIFAMKVLRKAKIACNAKDTAHTKAERNI
LEAIKHPFIVDLMYAFQTGGKLYLILECLSGGELFMQLEREGIFLEDTACFYLGEITLAL
GHLHSNGIIYRDLKPENIMLNSQGHIKLTDFGLCKESIHDGAVTHTFCGTIEYMAPEILM
RSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGKLVFPPYLTPDARDLIKK
FLKRNPSQRIGGGPGDAADVQRHPFFRHINWEDLLAKTIDPPFRPSLQSDDDVSQFDTRF
TRQTPVDSPDDGSLSESANQAFLGFTYVAPSVLESIKEGFSFQPKLRSPRRLNSSPRTPV
SPLKFSPFEAFKPSTAVELMELSAPPLVPVPEVTAPLPIKTPSGNKKKKGRGRASIHPSA
KKDVSLPLHLAAARYCNPTYLAFFLHPLSVFESELVTKEIVVGLMLRK
>Pelodiscus sinensis_RPS6KB2

>Takifugu rubripes_RPS6KB2(ENSTRUP_9008)
MAGVFDIDLETEDISDTELSCPFSLVQDDVCDFTVTESENVQTEEVELTSESVNRNSERV
GPDCFELLTVLGKGAYGKVFQVRKVQGAQMGKIFAMKVLKKAKVVCNAKDTAHTRAEREI
LETVRHPFIVDLLYAFQTGGKLYLILEYLSGGEVFMQLEKEGIFMEDTACFYLGEITLAL
GHLHSNGIIYRDLKPENIMLNHEGHIKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILT
RLGHNRAVDWWSLGALMYDMMTGSPPFTAENRKKTIDKILKCKLNLPPYLTIDARDLIKK
LLKKSPSQRLGSSKGDCADIQKHPFFRHISWDDLLNKRVEPPYKPQLQSDEDVSQFDTRF
TIQTPVDSPDDTTLSHSAELAFAGFTYVAPSVLESLKEGFSFEPRTRPVRRHNSSPRTPI
SPQNFSAAGPFKAGVSGDSDLHSHSSPPSALSPENGAASQPIRTPARVKKTDQSGPGLPL
S

>Gasterosteusaculeatus_RPS6KB2(ENSGACP_21548)
MAGVFDIDLETEDISAGQRIPDRRVSLCPVRPSVQTEEVELTSESVNRDSERVGPDCFEL
LTVLGKGAYGKVFQVRKVQGTQIGSIFAMKVLKKAKIVCNAKDTAHTRAEREILETVRHP
FLVDLLYAFQTGGKLYLILECLSGGELFMQLEKEGIFMEDTACFYLGEITLALGHLHSNG
IIYRDLKPENIMLNHQEGHIKLTDFGLCKESIHDGSVTHTFCGTIEYMAPEILTRSGHNR
AVDWWSLGALMYDMMTGSPPFTGENRKKTIDKILKCKLNLPPYLTIDAKDLIKKLLKKNP
AQRLGSSKTDCADIQKHPFFRHVNWAELLNRTVEPPYKPQLRSAEDVSQFDTRFTKQPPV
DSPDDSNLSHSAELAFAGFTYVAPSVLESLKEGFSFEPRARAVRRHNSSPHTPISPPNFS
QAGPFKSSMEVGESYPFSPTSPAPAAARASLDNGAASQPIRTPARNDKQKGHRRRTGK

>Oryzias latipes_RPS6KB2(ENSORLP_2818)
MAGVFDIDLETEDVSDTEVNRVKALNSQSDQAIIFVLNINKTEEVELTSEIVNRDSERVG
PDCFELLTVLGKGAYGKVFQVRKVQGLQIGKIFAMKVLKKAKIVRNAKDTAHTRAEREIL
ETVRHPFIVDLLYAFQTGGKLYLILECLSGGELFMQLEKEGIFMEDTACFYLGEITLALG
HLHSNGIIYRDLKPENIMLNHQGHIKLTDFGLCKESIHDGSVTHTFCGTIEYMAPEILTR
SGHNRAVDWWSLGALMYDMMTGSPPFTAENRKKTIDKILKCKLNLPPYLTIDARELIKKL
LKKNPAQRLG_SGKADAADIQKHSFFKQINWDDLLNKRVEPPYKPQLHSEEDVSQFDTRFT
RQTPVDSPDDSRLSHSAELAFAGFTYVAPSVLESLKEGFSFEPKSRHMRRHNSSPHTPIS
PLKFSPAGPFKAALDGEPDLFSPT

>Homo sapiens_GRK1(ENSP_334876)
MDFGSLETVVANSAFIAARGSFDGSSSQPSRDKKYLAKLKLPPLSKCESLRDSLSLEFES
VCLEQPIGKKLFQQFLQSAEKHLPALELWKDIEDYDTADNDLQPQKAQTILAQYLDPQAK
LFCSFLDEGIVAKFKEGPVEIQDGLFQPLLQATLAHLGQAPFQEYLGSLYFLRFLQWKWL
EAQPMGEDWFLDFRVLGKGGFGEVSACQMKATGKLYACKKLNKKRLKKRKGYQGAMVEKK
ILMKVHSRFIVSLAYAFETKADLCLVMTIMNGGDIRYHIYNVNEENPGFPEPRALFYTAQ
IICGLEHLHQRRIVYRDLKPENVLLDNDGNVRISDLGLAVELLDGQSKTKGYAGTPGFMA
PELLQGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKHRIISEPVKYPDKFS
QASKDFCEALLEKDPEKRLGFRDETCDKLRAHPLFKDLNWRQLEAGMLMPPFIPDSKTVY
AKDIQDVGAFSTVKGVAFDKTDTEFFQEFATGNCPIPWQEEMIETGIFGELNVWRSDGQM
PDDMKGISGGSSSSSKSGMCLVS

>Rattus norvegicus_GRK1(ENSRNOP_24999)
MDFGSLETVVANSAFIAARGSFDGSSTPSSRDKKYLAKLRLPPLSKCEGLRDSISLEFDN
LCSEQPIGKRLFQQFLKTDERHVPALELWKDIEDYDTADDDLRPQKAQAILAEYLDPQGT
LFCNFLDQGMVARVKEGPTGSQDGLFQPLLQATLEHLSQGPFQEYLGSLYFLRFLQWKWL
EAQPIGEDWFLDFRVLGKGGFGEVSACQMKATGKMYACKKLNKKRLKKRKGYQGAIVEKR
ILAKVHSRFIVSLAYAFETKTDLCLVMTIMNGGDVRYHIYNVDEENPGFPEPRAIYYTAQ
IISGLEHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLAVELKEGQNKTKGYAGTPGFMA
PELLRGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQRIISEPVKYPEKFS
QASKDFCEQLLEKDPEKRLGFRDGTCDALRANVLFKDISWRQLEAGMLIPPFIPDSRTVY
AKNIQDVGAFSTVKGVVFDKADTEFFQEFASGNCSIPWQEEMIETGVFGDLNVWRPDGQM
PDDMKGITVEEAAPTAKSGMCLIS

>Xenopus tropicalis_GRK1(ENSXETP_38567)
MDFGALETVVANSAYITARGSFDGGFNPQITRNKKYRARLKLPPLSECEHLKDKLDLQFE
NICVKQPIGKKLFQEFLESAEFTHIVEIWNDIEDYDVAEDEDRLYKARGIINKYLDSDSK
QFCHYLDEKAIIKVVQDCNKVSNMLFKQLHKSTLDYLKENAFAQYKESKYFSKFLQWKKL
EAQPIGDDWFMDFRILGKGGFGEVSATQMRATGKMYACKKLSKKRLKKRKGFEGAMVEKR
ILAKVHSRFIVSLAYAFQTKNDVCLVMTIMNGGDLRFHIYNMDEENPGIDEHRASFYTAQ
IISGLEHLHQNRIIYRDLKPENVLLDNDGNVRISDLGLAVELKEKKSKAKGYAGTPGFMA
PELLQGEEYDYAVDYFSLGVTLYEMIAARGPFRCRGEKVVENKELKNRILNDSVTY_SGKF
SLDCKSICEALLDKDPKKRMGFKNGNCNEIRVHLFFRGINWRKLEAGILPPPFAPDSRIV
YAKDIQDVGAFSTVKGVTLDESDNKLFDEFASGNISIPWQEEMVETGIFDEINSELNENN
VRRESIVNDNSAKSGVCRIA

>Danio rerio_GRK1(ENSDARP_76182)
MDIGGLTTVVANSAYISARGSFDGTANPASNRDKKYHSKLKLPHITVCEDLRETLDLQFR
SICVEQPIGKRLFQEYLETANEYKGPCRLWRDVEEYDTAEDKDRTQKAAKILQRYMEPSA
KHFCPFLPENGITKVKERHQEAADDLFVEILACVFDFLKEVPFTFYLETMYFKRFLQWKW
LEMQPVAEDWFLDFRVLGKGGFGEVSACQMRATGKLYACKKLNKKRLKKRKGYEGAMVEK
RILARVHSRFIVSLAYAFQTKTELCLVMTIMNGGDLRYHIYNVDENNPGFSEPRACYYAA
QIIQGLEHLHQKKIIYRDLKPENVLLDNEGNVRISDLGLAVELADGQEKTKGYAGTPGFM
APELLKGEEYDYSVDYFTLGVTLYEFIAAKGPFRTRGEKVENKEVKKRILNDPVTYSEKF
SENAKSICEGLLAKEVDKRLGFKNGTCDEIRTHPFFSQLNWRKLDAGILPPPFVPDSKTV
YAKDLDDVGAFSTVKGVCLEDDDKCFFDEFASGNISIPWQEEMIETGIYGELNVWGPGGA
VPNDLRRESILEQPPKSSTCSVS

>Takifugu rubripes_GRK1a(ENSTRUP_44116)
MDIGGLTTVVANSAYISARGSLDGTANPAANRDQKYHSRLKLPHITVCESLRETLDLGFQ
TVCVEQPIGKRLFQEFLNSKSEYKGSGHLWKDVEEYNMAEDADRVKKASKILSRYMEPGA
KYFCPFLPENGITAIREKHKDAGDDLFTDTLERVLDFLKEVPYTFFLESMYLKRFLQWKW
LEMQPMEEDWFLDFRVLGKGGFGEVSACQMRATGKLYACKKLNKKRLKKRKGYEGAMVEK
RILARVHSRFIVSLAYAFQTKTELCLVMTIMNGGDMSQFSPASRYHIYNVDENNPGFQEP
RACYYAAQIIQGLEHLHQKRIIYRDLKPENVLLDNEGNVRISDLGLAVELADHQDKIKGY
AGTPGFMAPELLKGEEYDYSVDYFALGVTVYEFIAAKGPFRTRGEKVENKVLKKRVLNDP
VTYPEKFSEKARSFCEDLLVREVDKRLGFRNGSCDDLRAHAFFSDINWRKLSAGLFQTFQ
NFGWISTGILTPPFLPDSKTVYAKNIDDVGAFSTVKGVQLEDADRDFFNEFASGNISIPW
QEEMIEMGVYGELTLWGPNGSLPNDLR

>Takifugu rubripes_GRK1b(ENSTRUP_33526)
MDIGGLTTVVANSAYINARGSIDGTNSAAARDKKFHSRLKLPHITVCEGLRDTLDLSFDT
VCVEQPIGKRLFREFLDANKEYHGSCRLWRDIESYDLAEDSDRAQKASKIVQRYMDPAAK
HYCPYLPEDVIAKVKEGQEAVGDDLFAAALATTLDYLREAPFMFFTESMYLKRFLQWKWL
ETQPIDTDWFLDFRVLGKGGFGEVSACQMKATGKLYACKKLNKKRLKKRKGYEGAMVEKR
ILEKVHSRFIVSLAYAFQTKEELCLIMTIMNGGDLKYHVYLVDENNPGFEEPRACFYIAQ
IIQGLEHLHQKRIIYRDLKPENVLLDNDGNVRISDLGLAVELKEGKTMTKGYAGTPGYMP
PEMLKGEKYDSCVDYFSLGVTLFEFLAAKNPFRNRGEKVEREEMKERMLTRQVEYPDNFS
QNAKLLCEGLLAKEMDKRMGFKNGCCDEIRAHPFFTDINWRKLNAGILPPPFVPDPRVVY
AKSLDDVGAFSSVKGVNLEDPDRSFFDEFSSGNISIPWQEEMIDMGIYRELNVWGPEGGV
PDDLRRESILEQPKSSTCCAS

>Tetraodon nigroviridis_GRK1a(ENSTNIP_12323)
MDIGGLTTVVANSAYISARGSLDGTANPAANRDRKYRSRLKLPHITLCEGLRETLDLGFQ
RVCVEQPIGKRLFQEFLDSKAEYKGPCHLWRDVEEYNMAEDADRVRKASKILSRYLEPGA
KCFCPFLPENGITAIKEKHDGAGDDLFTDILDSVLDFLKEVPYTFFLESMYLKRFLQWKW
LEMQPMEEDWFLDFRVLGKGGFGEVSACQMRATGKLYACKKLNKKRLKKRKGYEGAMVEK
RVLARVHSRFIVSLAYAFQTRTELCLVMTIMNGGDMRYHIYNVDENNPGFEEPRACYYAA
QIIQGLEHLHQKRIIYRDLKPENVLLDNEAGNVRISDLGLAVELAEDQEKIKGYAGTPGF
MAPELLRGEEYDYSVDYFALGVTLYEFLAAKGPFRTRGEKVENKVLKKRVLDDPVTYPEK
FSEEARSICQGLLVREVDKRLGFRSGSCDQLRAHPFFRDINWRKLNAGILTPPFLPDSKT
VYAKDVDDVGAFSTVKGVQLEDADRRFFDEFATGNISIPWQEEMIETGVYGELTVWRPDG
SLPNDLRRESILERPPKSSTCAVS

>Tetraodon nigroviridis_GRK1b(ENSTNIP_16893)
MDIGGLTTVVANSAYINARGSIDGTNSAAARDKKYHSRLKLPHITVCEGLRDSLDLAFDT
VCVEEPIGKRLFREFLDANKEYHGPCRLWKDIENYDLAEDSERAQKASKIVQRYMDPAAK
HYCPYLPEDVIAKVKEGQEAAGDDLFAAALATTLDYLREAPFTFFMESMYLKRFLQWKWL
EMQPIDAEWFLDFRVLGKGGFGEVSACQMKATGKLYACKKLNKKRLKKRKGYEGAMVEKR
ILEKVHSRFIVSLAYAFQTKEELCLVMTIMNGGDLKYHIYLVDENNPGFEEPRACFYIAQ
IIQGLEHLHQKRIIYRDLKPENVLLDNDGNVRISDLGLAVELKEGKTMTKGYAGTPGYMP
PEMLKGEKYDACVDYFSLGVTLFEFLAAKNPFRNRGEKVEREEMKERMLTREVDYPDNFS
QNAKLLCGGLLAKEVEKRLGFKNGSCDEIRAHPFFSGINWRKLNAGILPPPFVPDPRVVY
AKSLDDVGAFSSVKGVNLEDADRSFFDEFSSGNISIPWQEEMIDMGIYRELNVWGPDGGV
PDDLRRESILEQPKSSTCCAS

>Gasterosteusaculeatus_GRK1a(ENSGACP_20210)
MDIGGPATALANSAYISARGTSEGPGNPDSNRERKYHSLLKLPHISVCEGLRETLDLGFH
TVCVEQPIGKRLFQEFLDSNKDYGGACRLWKDVEEYNMAEDEGRAEKAGKILSQYMEPDA
KYFCPFLPENGITKLRGKRQEAGDDLFKETMDSVMDFLQEVPYTFFLESTYLKRFLQWKW
LEMQPIGEDCFLDFRVLGKGGFGEVSACQMKATGKLYACKKLNKKRLKKRNGNEAAMVEK
RILARVHSRFIVSLAYAFQTKTELCLVITIMNGGDLRYHIYNVDEKNPGLGEPRACYYAA
QIIQGLEHLHQKRIIYRDLKPENVLLDNQGNVRISDLGLAVELADGQFNIKGYAGTPGFM
APELLKGERYDFSVDYFTLGVTLYEFMAAKGPFRTRGEKLENKVVKKRILKDPVSYPQRF
SENARSICEGLLSKEVDKRLGFKNGTCDEIRAHAFFSGINWRKLNAGIVDPPFLPDSKTV
YAKDVYDVGGFSTVRGVQLEDKDEDFFNEFASGSISIPWQEEMIEMGIYGELTLWGADGA
SPKDLRRESILEQPAKSSTCALS

>Gasterosteusaculeatus_GRK1b(ENSGACP_4060s)
MDIGGLTTVVANSAYINARGSIDGTSTAAARDKKYHSRLKLPHITVCEHLRDTLDLAFDT
VCVEQPIGKRLFKEFLDSNAEHHGACRLWKDIEGYDLAEDSDRAKKASKIVERYMDPAAK
HYCSFLSEDIVAKVKESQGAAGDDLFAAAMASTLDFLREAPYATFLESLFLKRYLQWKWL
EMQPMDADWFLDFRVLGKGGFGEVSACQMKATGKLYACKKLNKKRLKKRKGYEGATVEKR
ILEKVHSRFIVSLAYAFQTKEELCLVMTIMNGGDLKYHIYLVDENNPGFEETRACFYIAQ
IIQGLEHLNQKRIIYRDLKPENVLLDNDGNVRISDLGLAVELKEGKTLTKGYAGTPGYMA
PEMLKGEKYDFSVDYFTLGVTLFEFMAAKNPFRNRGEKVERDEMKERMLTRVVTYPDNFS
EHAQALCDGLLAKEVDKRMSFKNGCCDEIRAHPFFRDINWRKLNAGIVPPPFVPDPKVVY
AKSLDDVGAFSSVKGVGLDDSDKTIFDEFSSGNIAIPWQEEMIETGIYGELNIWGPRGGV
PNDLRRESILEQPKSSTCCIS

>Oryzias latipes_GRK1a(ENSORLP_5942)
MDIGGLTTVVANSAYISARGSFDGTANPAANRDKKFHSRLKLPHITVCEGLRETLDLGFQ
TVCVEQPIGKRLFQEFLDSINEYKGPSRLWKDIEEYNMAEDEDRAKKASKILSRYMEPDA
KHYCPFLPENGITKVKEKHKEAGDELFSETMDSVMDFLKEVPYTFFLESMYLKRFLQWKW
LEMQPIGEDWFLDFRVLGKGGFGEVSACQMRATGKLYACKKLNKKRLKKRKGYEGAMVEK
RILARVHSRFIVSLAYAFQSKTELCLVMTIMNGGDLRYHIYNVDENNPGFDEPRACYYAA
QIIQGLEHLHQKRIIYRDLKPENVLLDNEGHVRISDLGLAVELADDQFKIKGYAGTPGFM
APELLNGEEYDYCVDYFTLGVTLYEFLAAKGPFRTRGEKVENKVVKKRILNDPVTYPEKF
SENGKSICEGLLCKEADKRLGFKNGSCDELRTHPFFSQINWRKLNAGILPPPFVPDSKTV
YAKDLDDVGAFSTVKGVQLEDVDTVFFDEFASGNIAIPWQEEMIETGIYGELTVWGPGGA
LPNDLRRESILEQPPKSSTCCAS

>Oryzias latipes_GRK1b(ENSORLP_15764)
MDIGGLTTVVANSAYINARGSIDGSNPATARDKKYHSRLKLPHITVCEGLKDTLDLAFDS
VCVEQPIGKRLFREFLEANQEYHGACRLWKDIEDYDLAEDSERAKKASKIVQRYMDPSAK
HFCPFLPEDIIAKVKENLEVVGDDLFAAALAKTLDYLREAPYVFFLESMYLKRFLQWKWL
EMQPMDADWFLDFRVLGKGGFGEVSACQMKATGKLYACKKLNKKRLKKRKGFEGAMVEKI
ILEKVHSRFIVSLAYAFQTKEELCLVMTIMNGGDLKYHIYLVDENNPGFDEPRACFYIAQ
IIQGLEHLHQKNIIYRDLKPENVLLDNDGKGNVRISDLGLAVELKEGKTKTKGYAGTPGY
MAPEMLKGDKYDSSVDYFTLGVTLYEFMAAKNPFRNRGEKVEREEMKERMLTREVTYQDN
FSEHARSLCDGLLARDVDKRMGFKNGCCDEIRAHPFFKDINWRKLNAGIIQPPFVPDPKV
VYAKSLDDVGAFSSVKGVTLEDPDKNFFDEFSSGNIPIPWQEEMIEMGIYSELNLWGPDG
TVPNDLRRESILEQPKSSTCHIC

>Homo sapiens_AKT1(ENSP_270202)
MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQC
QLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDF
RSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI
LKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLS
RERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI
KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
ILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKK
LSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA

>Mus musculus_AKT1(ENSMUSP_1780)
MNDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQRESPLNNFSVAQC
QLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWATAIQTVADGLKRQEEETMDF
RSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI
LKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLS
RERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI
KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
ILMEEIRFPRTLGPEAKSLLSGLLKKDPTQRLGGGSEDAKEIMQHRFFANIVWQDVYEKK
LSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA

>Rattus norvegicus_AKT1(ENSRNOP_38369)
MNDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVEQRESPLNNFSVAQC
QLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKRQEEETMDF
RSGSPSDNSGAEEMEVALAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI
LKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLS
RERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI
KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
ILMEEIRFPRTLGPEAKSLLSGLLKKDPTQRLGGGSEDAKEIMQHRFFANIVWQDVYEKK
LSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA
\t
>Gallus gallus_AKT1(ENSGALP_36651)
MNEVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQRESPLNNFSVAQC
QLMKTERPKPNTFIIRCLQWTTVIERTFHVETPEEREEWTKAIQTVADSLKKQEEEMMDF
RSGSPSDNSGAEEMEVSMTKPKHKVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI
LKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLS
RERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI
KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
ILMEEIRFPRTLSPEAKSLLSGLLKKDPKQRLGGGPDDAKEIMQHKFFAGIVWQDVYEKK
LVPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMDCVDNERRPHFPQFSYSASGTA

>Takifugu rubripes_AKT1(ENSTRUP_34366)
MTNVVIVKEGWLHKRGEYIKTWRPRYFLLKTDGTFIGYKERPQDVDQLETPLNNFSVAQC
QLMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTKAIQAVAEGLQKQEEEMMDS
SPDPMDMEVCLTKIRHKVTMHDFEYLKLLGKGTFGKVILVKEKATGHYYAMKILKKEVIV
AKDEVAHTLTENRVLQNSKHPFLTGLKYSFQTHDRLCFVMEYANGGELFFHLSRDRVFSE
ERARFYGAEIVSALDYLHAERNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMK
TFCGTPEYLAPENKVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMED
IRFPRTLGPEARSLLSGLLKKDPMQRLGGGPDDAKEIMQHKFFAGIEWKDVYEKKLVPPF
KPQVTSETDTRYFDEEFTAQTITITPPGQDDSMESFDSERRPHFPQFSYSASGTA

>Tetraodon nigroviridis_AKT1(ENSTNIP_22715)
MTNVVIVKEGWLHKRVGEYIKTWRPRYFLLKSDGTFIGYKERPQDVDQLETPLNNFSVAQ
CQLMKTERPKPNTFIIRCLQWTTVIERTFHVETPEEREEWTKAIQAVAEGLQKQEEEMMD
SSPDPMDMEVCLTKIRHKVTMHDFEYLKLLGKGTFGKVILVKEKATGHYYAMKILKKEVI
VAKDEVAHTLTENRVLQNSKHPFLTGLKYSFQTHDRLCFVMEYANGGELFFHLSRDRVFS
EERARFYGAEIVSALDYLHAERNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATM
KTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDI
RFPRTLGPEARSLLSGLLKKDPMQRLGGGPDDAKEIMQHKFFAGIEWKDVYEKKLVPPFK
PQVTSETDTRYFDEEFTAQTITITPPGQDDSMESFDSERRPHFPQFSYSASGTA

>Gasterosteusaculeatus_AKT1(ENSGACP_8334)
IFEVAIKQSATVHHRREYIKTWRPRYFLLKSDGTFIGYKERPQDVDQLETPLNNFSVAQC
QLMKTERPKPNTFIIRCLQWTTVIERTFHVETPEEREEWTKAIQAVAEGLQKQEEEMMDS
SPDPMDMEIYLTKPRQKVTFNSNAYSSQSLPSPPPLTPQLLFQTSAAGDLAPDSVSTGFL
IPTCVDEVAHTLTENRVLQNSKHPFLTGLKYSFQTHDRLCFVMEYANGGELFFHLSRDRV
FSEERARFYGAEIVSALDYLHAERNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGA
TMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILME
DIRFPRTLGPEARSLLSGLLKKEPTQRLGGGSEDAKEIMQHKFFAGIEWQDVYEKKLVPP
FKPQVTSETDTRYFDEEFTAQTITITPPGQDDSMESFDSERRPHFPQFSYSASGTA

>Oryzias latipes_AKT1(ENSORLP_21301)
SKSVLKTQFSSNLGEYIKTWRPRYFLLKSDGTFIGYKERPQDVDQLETPLNNFSVAQCQL
MKTERPKANTFIIRCLQWTTVIERTFHVETPEEREEWTKAIQAVAEGLQKQEEEMMDSSP
DPMDMEVYLTKPRQKVTMHDFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAK
DEVAHTLTENRVLQNSKHPFLTGLKYSFQTHDRLCFVMEYANGGELFFHLSRDRVFSEER
ARFYGAEIVSALDYLHAERNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTF
CGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIRFP
RTLGPEARSLLSGLLKKDPMQRLGGGPNDAKEIMQHKFFAGIIWQDVYEKKLVPPFKPQV
TSETDTRYFDEEFTAQTITITPPGQDDSMESFDSERRPHFPQFSYSASGTA

>Homo sapiens_RPS6Kb1(ENSP_225577)
MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG
PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF
AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL
FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC
KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK
TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL
LARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLE
SVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSG
IEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL

>Mus musculus_RPS6Kb1(ENSMUSP_119715)
MRRRRRRDGFYLAPDFRHREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG
PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF
AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL
FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC
KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK
TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL
LARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLE
SVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSG
IEQMDVTVSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL

>Gallus gallus_RPS6Kb1(ENSGALP_8334)
MAGVFDIDLDQPEDAGSDEELEEGGQLSESMDHGGVGQYDLGMEHCEKFEISETSVNRGP
EKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAE
RNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEIS
MALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPE
ILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDL
LKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWDELLARKVEPPFKPLLQSEEDVSQFD
SKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLESVKEKFSFEPKIRSPRRFIGSPR
TPVSPVKFSPGEFWGRGASASASNTQTPVEYPMETSGIEQMDVTVCGEASAPLPIRQPNS
GPYKKQAFPMISKRPEHLRMNL

>Anolis carolinensis_RPS6Kb1(ENSACAP_12793)
EAMAGVFDIDLDQPDEAASDEELEEGGHLSESMDHGGVGPYDLMEHCEKFEISETSVNRG
PEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTSKIFAMKVLKKAMIVRNAKDTAHTKA
ERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEI
SMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAP
EILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARD
LLKKLLKRNAASRLGAGPGDAGEVQGHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQF
DAKFTRQTPVDSPDDSALSESANQVFLGFTYVAPSVLESVKEKFSFEPKIRSPRRFIGSP
RTPVSPVKFCPGDFWGRGSSSGMTNAQAPVEYPMESSGIEHMDVTVCGEASAPLPIRQTN
TGPYKKQAFPMISKRPEHLRMNL

>Takifugu rubripes_RPS6Kb1(ENSTRUP_20996)
ASAMAGIFDIDLDQPENVSDDDLDDGGQLNEYMDQCGSFEFNMDDCEKFEISENSVNKGK
EQIRPECFELLKVLGKGGYGKVFQVRKVSGAT_SGKIFAMKVLKKAMIVRNAKDTAHTKAE
RNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEIS
MALGHLHQKGIIYRDLKPENIMLNNIGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPE
ILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLSLPPYLTQEARDL
LKKLLKRNASLRLGAGPGDAAEVQAHPFFRHINWDDLLAHKVEPPFKPFLQSADDASQFD
SKFTSQTPVDSPDDSMLSESANQVFLGFTYVAPSVLENVKEKFSFEPKVRSLRKFPGSPR
TPVSPVKFVGGDCWLRGPALTTCPSHLPPCSVEQPMEVSTVEQMDTSSSGTTPSEASAPL
PIKHPPGISTAPYKKHVYPMNSKRPEHLRMNL

>Tetraodon nigroviridis_RPS6Kb1(ENSTNIP_14588)
IRRRRQKKLYKQLPIFFDAIAPAMAGIFDIDLDQPEENISDDELDDGGQLNEYMEQCSSF
DFYMEDCEKFEISENSVNKGTEQIRPECFELLKVLGKGGYGKVFQVRKVSGVT_SGKIFAM
KVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFM
QLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNNDGHVKLTDFGLCKE
SIHDGTVTHTFCGTIEYMAPEILMRGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTID
KILKCKLSLPPYLTQEARDLLKKLLRRNASLRLGAGPGDAAEVQAHPFFRHVNWDDLLAH
KVEPPFKPFLQSADDASQFDSKFTSQTPVDSPDDSALSESANQVFLGFTYVAPSVLENVK
EKFSFEPKVRSPRKFPGSPRTPVSPVKFARGDCWPRGPTLSACPSHLMTRIAAEQPVAEA
AAGEPMDTTPSEASAPLPYKKHTYPVNAKRPEHLRMN

>Gasterosteusaculeatus_RPS6Kb1(ENSGACP_26703)
MAGVFDIDLDQPDGNVSDDDLEDGGQPGEYMDQCSGFDFNMDDCEKFEISENSVNQGTEP
IRPECFELLKVLGKGGYGKVFQVRKVSGST_SGKIFAMKVLKKAMIVRNAKDTAHTKAERN
ILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMA
LGHLHQKGIIYRDLKPENIMLNNNGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEIL
MRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLSLPPYLTQEARDLLK
KLLKRNASLRLGAGPGDAAEVQAHPFFRHINWDDLLARKVEPPFKPYLQSADDVSQFDSK
FTSQTPVDSPDDSTLSESANQAFLGFTYVAPSVLENVKERFSLEPKVRSPRKFPGSPRTP
VSPVKFVAGDCWLRGPPATGRTAEQPMEVSAAETMDTSGSGSEASAPLPIRLPKGINAGH
SKKQTYPMNSKRPEHLRMNL

>Oryzias latipes_RPS6Kb1(ENSORLP_15389)
DMAGVFDIDLDQPDDNVSDDELEDGAQLGEYMEQCSSFDFNMDDCEKFELSENNVNKGTE
QIRPECFELLKVLGKGGYGKVFQVRKVSGAS_SGKIYAMKVLKKAMIVRNAKDTAHTKAER
NILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISM
ALGHLHQKGIIYRDLKPENIMLNDSGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEI
LMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLSLPPYLTQEARDLL
KKLLKRSASSRLGGGPGDAAEVQVHPFFRHINWDDLLARKVEPPFKPFLQSADDVSQFDS
KFTSQTPVDSPDDSTLSESANQVFLGFTYVAPSVLENVKEKFSFEPKLRSPRKFPGSPRT
LLSPLKFSGGDSWLRGPLPSGNPSTVCPGSGEHPMEVSGVEQMDTSSSCTSEVSAPLPIR
PPSGIQAGPFKKQAYPMNSKRPEHLRMNL

>Homo sapiens_AKT2(ENSP_471369)
MKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRAPGEDPMDY
KCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKI
LRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLS
RERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGIS
DGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELI
LMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKL
LPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRCECLGPPRWCACPRGGGMGSALNSLLK
EGPRRPPLHVWEISPSLLSGPFAVGPLWTW

>Mus musculus_AKT2(ENSMUSP_103981)
MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC
QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRGPGEDAM
DYKCGSPSDSSTSEMMEVAVNKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM
KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH
LSRERVFTEDRARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG
ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE
LILMEEIRFPRTLGPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQK
KLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLDPLELDQRTHFPQFSYSASIR
E

>Rattus norvegicus_AKT2(ENSRNOP_25303)
MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC
QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWIRAIQMVANSLKQRGPGEDAM
DYKCGSPSDSSTSEMMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM
KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH
LSRERVFTEDRARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG
ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE
LILMEEIRFPRTLGPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQK
KLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGSLELDQRTHFPQFSYSASIR
E

>Anolis carolinensis_AKT2(ENSACAP_2886)
MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKEKPETTDQSLPPLNDFSVAEC
QLMKVERPRPNTFIIRCLQWTTVIERTFHVDSPDEREEWIQAIQMVANSLKNQEPEEDRM
DYKCGSPSDSTGAEEMEVAVTKTRAKATMNDFDYLKLLGKGTFGKVILVREKATGRYYAM
KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTNDRLCFVMEYANGGELFFH
LSRERVFTEDRARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG
ITDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE
LILMEEIRFPRTLSPEAKALLAGLLKKDPKQRLGGGPNDAKEVMEHRFFAAINWQDVVQK
KLIPPFKPQVTSEIDTRYFDDEFTAQSITITPPDRYDSLDSLDADQRTHFPQFSYSASIR
E

>Xenopus tropicalis_AKT2(ENSXETP_37022)
MNEVMVIKEGWLQKRGEYIKTWRPRYFLLKSDGSFIGYKEKPESTEHSSIPPLNNFSVAE
CQLMKTERPRPNTFVIRCLQWTTVIERTFHVDTPEEREEWIIAIQTVANGLKNQVAEDEE
EEAMEVKYGSPSDVSSAEQMDVAMSKGRPKVTMNDFDYLKLLGKGTFGKVILVREKSSGR
YYAMKILRKEVIIAKDEVAHTLTESRVLQNTKHPFLTALKYAFQTSDRLCFVMEYANGGE
LFFHLSRERVFTEDRARFYGAEIVSALEYLHSRNVVYRDIKLENLMLDKDGHVKITDFGL
CKEGITDGATMRTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHE
RLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPNDAQEVMSHRFFASINWQD
VTERKLTPPFKPQVTSEIDTRYFDDEFTAQSITLTPPDRYDNLDALESDQRPHFPQFSYS
ASIRE

>Danio rerio_AKT2(ENSDARP_23119)
MNEISVVREGWLHKRGEYIKTWRPRYFILKSDGSFIGYKEKPETSDANQPPLNNFSVAEC
QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSNSEREEWIRAIQAVANGLKSREEDEPMD
INFGSPGDNSLEGMEAAITKSRTKVTMSDFDYLKLLGKGTFGKVILVREKATGMYYAMKI
LRKEVIIAKDEVAHTITESRVLQNTRHPFLTTLKYAFQTRDRLCFVMEYANGGELFFHLS
RERVFTEDRARFYGAEIVSALEYLHSKDVVYRDLKLENLMLDKDGHIKITDFGLCKEGIT
NEATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELI
LMEEIRFPRNLSPEAKALLAGLLKKDPKQRLGGGPEDAKEVMTHKFFNNMNWQDVLQKKL
VPPFKPQVTSETDTRYFDDEFTAQTITVTPPDQYDSLDAEDPDTRTHFSQFSYSASVRE

>Takifugu rubripes_AKT2(ENSTRUP_26604)
MDEVSVVREGWLFKRGEYIKTWRPRYFILKSDGSFIGYKEKPEVCDHSLPPLNNFSVAEC
QLMKTERPRPNTFVIRCLQWTSVIERTFHVDNHDDRKKWMQSIQAVANSLKSQQQDEERM
EIKFGSPCDNSGSENMEIAAFKSRTKVTMSDFDYLKLLGKGTFGKVILVKEKATGVYYAM
KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTTLKYAFQTHDRLCFVMEYANGGELFFH
LSRDRVFTEDRARFYGAEIVSALEYLHSCNVVYRDLKLENLMLDKDGHIKITDFGLCKEG
ITDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE
LILMEEIRFPKSLAPEGKELLNGLLRKDPKQRLGGGPDDAKDVMSHRFFTSINWQDVIEK
KLIPPFKPQVMSETDTRYFDEEFTAQTITITPPDRYGSLDAKESDHRTHFPQFSYSASIW
E

>Tetraodon nigroviridis_AKT2a(ENSTNIP_7149)
MNEASVVREGWLFKRGEYIKTWRPRYFILKSDGSFIGYKEKPEVCDHSLPPLNNFSVAEC
QLMKTERPRPNTFVIRCLQWTSVIERTFHVDSPEERLRKDWMRSLQAVANSLKCQQQDEE
RMEIKFGSPCDSSGSEDMEIAASKSRTKVTMSDFDYLKLLGKGTFGKVILVKEKATGMYY
AMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTTLKYAFQTHDRLCFVMEYANGGELF
FHLSRDRVFPEDRARFYGAEIVSALEYLHSCNVVYRDLKLENLMLDKDGHIKITDFGLCK
EGITDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERL
FELILMEEIRFPKSLAPEAKELLSGLLKKDPKQRLGGGPDDAKDVMSHRFFTSVNWQDVL
EKKLVPPFKPQMSETDTRYFDDEFTAQSITITPPDRYGSLEAKESDQRTHFPQFSYSASI
WE

>Tetraodon nigroviridis_AKT2b(ENSTNIP_11431)
MNEVNIVKEGWLQKRGEYIKTWRPRYFILKSDGSFIGYKEKPDLNDQTSPPLNNFSVAGQ
SSIETKLKDPRPNTFVIRCLQWTTVIERNFHVDSNEDREEWMWAIQSVANSLKMREQDEE
EPMDLLGSPNESSLEEMEVATSKRCTRVTMNDFEYLKLLGKGTFGKVILVKEKATGVHYA
MKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTTLKYAFQTNDRLCFVMEYANGGELFF
HMSRERVFTEDRARFYGAEIVSALEYLHSRDVVYRDLKLENLMLDKDGHIKITDFGLCKE
GITPDATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLF
ELILMEDIRFPRNLSPEAKSLLAGLLKKDPKQRLGGGPDDAKEVMTHKFFTNINWQDVVQ
KKLTPLFKPQVTSETDTRYFDEEFTAQTITLTPPDKYTSLDSEDPSQQAHFPQFSYSASI
RE

>Gasterosteusaculeatus_AKT2a(ENSGACP_8322)
MNEVSVVREGWLHKRGEYIKTWRPRYFILKSDGSFIGYKEKPEVSSDHSLPPLNNFSVAE
CQLMKTERPRPNTFVIRCLQWTSVIERTFHVDSNEEREEWMRSIQAVANSLKSQQHDEEP
MEIKFGSPSDISGSEEMEIAVSKSRTKVNMSDFDYLKLLGKGTFGKVILVKEKATGMYYA
MKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTTLKYAFQTNDRLCFVMEYANGGELFF
HLSRDRVFSEDRARFYGAEIVSALEYLHSRNVVYRDLKAQLENLMLDKDGHIKITDFGLC
KEGITDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHER
LFELILMEEIRFPKNLAPEAKALLAGLLKKDPKQRLGGGPDDAKEVMIHKFFTSINWQDV
LEKKLVPPFKPQVTSETDTRYFDDEFTAQTITITPPDKCE

>Gasterosteusaculeatus_AKT2b(ENSGACP_26547)
MNEVNIVREGWLHKRGEYIKTWRPRYFMLKSNGSFIGYKEKPDLSEQTSPPLNNFSVAEC
QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSNEEREEWMRAIQSVANGLKIREQEEEEP
MDMFGSPNKSSLEEMEVSMSKNRSKVTMSDFEYLKLLGKGTFGKVILVKERSTGVHYAMK
ILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTTLKYAFQTNDRLCFVMEYANGGELFFHL
SRERVFTEDRARFYGAEIVSALEYLHSSDVVYRDLKLENLMLDKDGHIKITDFGLCKEGI
TPDATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFEL
ILMEEIRFPRNLSPEAKSLLAGLLKKDPKQRLGGGPYDAKEVMSHKFFIAINWQDVVQRK
LAPLFRPQVTSETDTRYFDDEFTAQTITLTPPDKYNCLDCEDPSQQAHFPQFSYSASIRE

>Oryzias latipes_AKT2a(ENSORLP_17781)
MNEVSVVKKGWLHKRGEYIKTWRPRYFILKTDGSFIGYKEKPEVSGDHSLPPLNNFSVAE
CQLMKTERPRPNTFVIRCLQWTSVIERTFHVDSNEEREEWMRAIQAVTNSLKSQQQDEEP
MEIKFGSPSDSSGTEEMEIAVSKSCTKVTMSDFDYLKLLGKGTFGKVILVKEKATGMYYA
MKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTTLKYAFQTHDRLCFVMEYANGGELFF
HLSRDRVFTEDRARFYGAEIVSALEYLHSRDVVYRDLKLENLMLDKDGHIKITDFGLCKE
GVTDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLF
ELILMEEIRFPKNLAPEAKALLAGLLKKDPKQRLGGGPDDAKEVMTHKFFISINWQDVID
KKLVPPFKPQVTSETDTRYFDDEFTAQSITITPPDKYDSIDPEDSDQRTHFPQFSYSASI
RE

>Oryzias latipes_AKT2b(ENSORLP_6529)
MTEVTVVREGWLHKRGEYIKTWRPRYFILKSDGSFIGYKEKPDLGDSTSPPLNNFSVAEC
QIMKTERPRPNTFVIRCLQWTTVIERTFHVESNVEREEWMQAIQSVANGLKMREQEEEPM
DMFSSPCESSLEEMEVVMSKSRNKRKTMNDFEYLKLLGKGTFGKVILVKEKSTGVHYAMK
ILRKMVIIAKDEVAHTVTESRVLQNTRHPFLTTLKYAFQTNDRLCFVMEYANGGELFFHL
SRDRVFTEDRARFYGAEIVSALEYLHSRDVVYRDLKLENLMLDKDGHIKITDFGLCKEGI
TPDATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFEL
ILMEEIRFPRNLSPEAKSLLAGLLKKDPKQRLGGGPNDAKEVMNHRFFININWQDVVQKK
LTPPFKPQVTSETDTRYFDEEFTAQTITVTPPDKCLSDHALDCNDPIQEAHFPQFSYSAS
IRE

>Homo sapiens_SGK2(ENSP_340608)
MQGLLTSGRKPSGGGRCTGRGGWRGQWCLKPWMGGADPPTPTLSCLLLPVPPELPDHCYR
MNSSPAGTPSPQPSRANGNINLGPSANPNAQPTDFDFLKVIGKGNYGKVLLAKRKSDGAF
YAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGE
LFFHLQRERRFLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGL
CKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVS
QMYENILHQPLQIPGGRTVAACDLLQSLLHKDQRQRLGSKADFLEIKNHVFFSPINWDDL
YHKRLTPPFNPNVTGPADLKHFDPEFTQEAVSKSIGCTPDTVASSSGASSAFLGFSYAPE
DDDILDC

>Mus musculus_SGK2(ENSMUSP_18012)
MASSPVGVPSPQPSRANGNINLGPSANPNARPTDFDFLKVIGKGNYGKVLLAKRKSDGAF
YAVKVLQKKSILKNKEQNHIMAERNVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGE
LFFHLQRERRFLEPRARFYTAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGL
CKECVEPEETTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFFNTDVA
QMYENILHQPLQIPGGRTVAACDLLQGLLHKDQRQRLGSKEDFLDIKNHMFFSPINWDDL
YHKRLTPPFNPNVEGPADLKHFDPEFTQEAVSKSIGCTPDTVASSSGASSAFLGFSYAQD
DDDILDS

>Rattus norvegicus_SGK2(ENSRNOP_40718)
MASSPVGVPSPQPSRANGNINLGPSANPNARPTDFDFLKVIGKGNYGKVLLAKRKSDGAF
YAVKVLQKKSILKNKEQSHIMAERNVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGE
LFFHLQREHRFLEPRARFYTAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGL
CKECVEPEETTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFFNTDVA
QMYENILHQPLQIPGGRTVAACDLLQGLLHKDQRQRLGSKEDFLDIKNHMFFSPINWDDL
YHKRLTPPFNPNVEGPADLKFDPEFTQEAVSKSIGCTPDTMSSSSGASSAFLGFSYAQDD
DDILDS

>Gallus gallus_SGK2(ENSGALP_5583)
MDRSRTSDSSAQPPTPTDNINLGPSANPNAKPTDFDFLKVIGKGSFGKVLLAKRKSDGTF
YAVKVLHKKTILKKKEQNHIMAERNVLLKNVKHPFLVGLHYSFQTSEKLYFVLDYVNGGE
LFFHLQRERCFREPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGL
CKEGMEEEETTSTFCGTPEYLAPEVLKKQPYDRTVDWWCLGAVLYEMLFGLPPFYSRDVS
QMYDNILHKQLQIQGSKTVAACDILHGLLHKDQKRRLGAKTDFLEIKNHVFFSPINWDDL
YHKRITPPFNPNVAGPADLRHFDPEFTQEAISASITHTPDLAASSSSASDAFLGFSYAPT
EEDF

>Anolis carolinensis_SGK2(ENSACAP_2340)
MHPPGTESVFTTLGKTKGLIKQGRERLEQTIKASSSRLSSYTERVVALMERSKSPDGNSL
PSSPTDNINLGPSANPNAKPTDFDFLKIIGKGSFGKVLLAKRKSDGRFYAVKVLQKKSIL
KKKEQNHIMAERNVLLKNVKHPFLVGLHYSFQTKEKLYFVLDYVNGGELFFHLQRERCFR
EPRARFYAAEMASAVGYLHSLNIIYRDLKPENILLDCQGHIVLTDFGLCKEGMEPEETTS
TFCGTPEYLAPEVLKKQPYDRTVDWWCLGAVLYEMLFGLPPFYSRDVSQMYDNILHKPLQ
IQGTKTIAACDILQGLLHKDQKKRLGAKTDFLEIKSHVFFSPINWDDLYNKKITPPFDPN
VAGPADLRHFDPEFTQETVSSSIIRTPDLAASSSSATDAFLGFSYAPNDED

>Xenopus tropicalis_SGK2(ENSXETP_26450)
MSSTINLGPSANPNAKPTDFDFLKVIGKGSFGKVLLAKRKCDNNFYAVKVLQKKTILKKK
EQNHIMAERNVLLKNLKHPFLVGLHYSFQTAEKLYFVLDYVNGGELFLHLQRERCFLEPR
ARFYAAEVACALGYLHSQNIIYRDLKPENILLDSQGHVVLTDFGLCKEGMEPEETTSTFC
GTPEYLAPEVLRKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRDVSQMYDNILSQPLQLPG
CKTTATCDILRGLLHKDQRCRLGAKADFQEIKNHVFFSPINWDDLYHKRIAPPYNPNVAG
PGDLRHFDPEFTQEAVPSSVGRTPDLNVSSCSSSSAFLGFSYAQSDDDYLS

>Danio rerio_SGK2(ENSDARP_86932)
MAYYDPTPPSPSNEVNLGASVNPHAKPTDFDFLAVIGKGTFGKVLLAKLKADGKFYAVKV
LQKKVILKKKEQKNIMAERNVLLKSLKHPFLVGLHYSFQTSEKLYFVLDYVNGGELFYHL
QRERCFSEPRARFYTAEVASAIGYLHSLNIVYRDLKPENILLDYQGHVVLTDFGLCKEGI
EPEGTTTTFCGTPEYLAPEVLRKEPYDRTVDWWCLGAVLHEMLYSLPPFYSRDVSEMYDA
ILHKPLHLPPGKSESACLLLYGLLQKDQHRRTGAIADFLEIKNHVFFAPINWDDLYHKRI
NPPYNPNVRGPADLQHIDPEFTREMVPHSVGRTPEPTPSLATSSSNAFTGFSYISGEDGF
L

>Takifugu rubripes_SGK2(ENSTRUP_23371)
FSSHLFVLQQRSQSSSHNDVNLGPSANPHSSARPTDFDFLAVIGKGTFGKVLLAKHKADG
SFYAVKVLQKKIILKKKEQKNIMAERNVLLKSLKHPFLVRLHYSFQTAEKLYFVLDYVNG
GELFFHLQRERCFSEPRARFYTAEVASAIGYLHSLNIVYRDLKPENILLDSQGHVVLTDF
GLCKEGVEPEGTTSTFCGTPEYLAPEVLRKEPYDRTVDWWCLGTVLYEMIYSLPPFYSRD
VGEMYDGILHKPLQLPPGKSDAISSLLVGLLQKDQHRRLGAIADFLEIKNHVFFTPINWD
DLYHKRITPPYNPNVRGPADTQHIDPEFTREMVSGSVSRTPEFTASASASNAFNGFSFVA
TEDSFL

>Tetraodon nigroviridis_SGK2(ENSTNIP_14976)
SSSHDDVNLGPSANPHARPTDFDFLAVIGKGTFGKVLLAKHKTDSSFYAVKVLQKKVILK
KKEQKNIMAERNVLLKSLKHPFLVRLHYSFQTAEKLYFVLDYVNGGELFFHLQRERCFSE
PRARFYAAEVASAIGYLHSLNIVYRDLKPENILLDSQGHVVLTDFGLCKEGVEPEGTTST
FCGTPEYLAPEVLRKEPYDRTVDWWCLGAVLYEMIYSLPPFYSRDVGVMYDGILHKPLQL
PPGKSDAVCSLLVGLLQKDQHRRLGAIADFLEIKNHVFFTPINWDDLYHKRITPPYNPNV
RGPADTQHIDPEFTREMVSSSVSQTPEFTASASASNAFNGFSFVATEDSFL

>Gasterosteusaculeatus_SGK2(ENSGACP_8027)
VSCRVAGQPKLRSPSSSPHADVNLGPSANPHARPTDFDFLAVIGKGTFGKVLLAKLKADS
KFYAVKVLQKKVILKKKEQKNIMAERNVLLKSLKHPFLVRLHYSFQTPEKLYFVLDYVNG
GELFFHLQRERCFSEPRARFYAAEVASAIGYLHSLNIVYRDLKPENILLDSQGHVVLTDF
GLCKEGIEPEGTTSTFCGTPEYLAPEVLRKEAYDRTVDWWCLGAVTYEMIHSLPPFYSRD
VDEMYDGILHKPLPLPPGKSAAVCSLLVGLLQKDQHRRLGAIADFLEIKNHAFFSSINWD
DLDHKRITPPYNPNVRGPADTQHIDPEFTREMVPNSVSRSPELNGSSSSNNAFNGFSFVG
TEDGFL

>Oryzias latipes_SGK2(ENSORLP_4348)
MAHSNLRSASPSALGDVNLGPSANPHARPTDFDFLAVIGKGTFGKVLLAKLKADNKFYAV
KVLQKKIILKKKEQKNIMAERNVLLKSLKHPFLVRLHYSFQTSEKLYFVLDYVNGGELFF
HLQRERCFSEPRARFYAAEVASAIGYLHSLNIVYRDLKPENILLDSQGHVVLTDFGLCKE
GVEPEGTTTTFCGTPEYLAPEVLRKEPYDRTVDWWCLGAVLYEMVYSLPPFYSRDVGEMY
DGILHKPLFLPPGKSEAIRSLLVGLLQKDPHRRLGSIADFLEIKNHSFFTPINWDDLYHK
RITPPYNPNVRGPADTQNIDPEFTREMVPNSVSQTPDLNASFSSSNAFHGFSFVATEDSF
L

>Homo sapiens_ADRBK2(ENSP_317578)
MADLEAVLADVSYLMAMEKSKATPAARASKRIVLPEPSIRSVMQKYLAERNEITFDKIFN
QKIGFLLFKDFCLNEINEAVPQVKFYEEIKEYEKLDNEEDRLCRSRQIYDAYIMKELLSC
SHPFSKQAVEHVQSHLSKKQVTSTLFQPYIEEICESLRGDIFQKFMESDKFTRFCQWKNV
ELNIHLTMNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER
IMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATE
IILGLEHMHNRFVVYRDLKPANILLDEHGHARISDLGLACDFSKKKPHASVGTHGYMAPE
VLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPDTFSPE
LKSLLEGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPPRGEVNAA
DAFDIGSFDEEDTKGIKLLDCDQELYKNFPLVISERWQQEVTETVYEAVNADTDKIEARK
RAKNKQLGHEEDYALGKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQNL
LTMEQILSVEETQIKDKKCILFRIKGGKQFVLQCESDPEFVQWKKELNETFKEAQRLLRR
APKFLNKPRSGTVELPKPSLCHRNSNGL

>Gallus gallus_ADRBK2(ENSGALP_8839)
IRSVMQKYLEERGELTFDKIFHQKIGFLLFKDYCMNEIDEAVPQLKFYEEIKEYEKLDSE
EERLSRSRQIYDTYIMKELLSCSHPFSKQAVDHVQTHLSKKQVPASLFQPYIEEICDSLR
GKIFQKFMESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYA
MKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGD
LHYHLSQHGVFSEKEMRFYATEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGL
ACDFSKKKPHASVGTHGYMAPEVLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKD
KHEIDRMTLTVNVELPDSFSPELKSLLEGLLQRDVSKRLGCQGRSAQEVKEHPFFKGIDW
QQVYLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDSDQELYKNFPLVISERWQ
QEVAETVYDAVNADMDKIEARKRAKNKQLGHEEDYALGKDCIMHGYMLKLGNPFLTQWQR
RYFYLFPNRLEWRGEGESRQNLLTMEQILSVEETQIKDKKCILLRIKGGKQFVLQCESDP
EFVQWKKELTEAFTEAQRLLRRAPKFLNKSRSTVVELSKPPLSHRNSNGL

>Xenopus tropicalis_ADRBK2(ENSXETP_60898)
IGFLLFKDFCMNDMDEGVPQLKFYEEIAELSSLCLRNERGGRGREYIYLFILKSKTNCSS
PFSKQAVDHVQAHLAKKQVPPTLFQPYIEEICDSLRGKIFQRFIESDRFTRFCQWKNVEL
NIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIM
LSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYAAEII
LGLEHMHHRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVL
QKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMNVELPDSFSPELK
SLLEGLLQRDVSKRLGCQGGGAQEVKEHAFFKGIDWQQVYLQKYPPPLIPPRGEVNAADA
FDIGSFDEEDTKGIKLLDSDQELYKNFPLVISERWQQEVAETVYEAVNADTDKIEARKRA
KNKQLGHEEDYALGKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQNLLT
MEQIVSVEDTQIKDKKCILLRIKGAKQFVLQCESDPEFVQWKKELTEAFTEAQRLLRRAP
KFLNNPRSAVVEIAKPPLSHRNSNGL

>Danio rerio_ADRBK2(ENSDARP_7164)
MADLEAVLADVSYLMAMEKSKSTPAARASKKIILPEPSIRSVMQKYLEERDELAFDKIFN
QKIGFLLFKDFCMNEIDEAVPQLKFYEEIKEYEKLDSEEERLTRSRQIYDVYIMKELLSC
SHPFSKKAVDHVQTHLAKKQVPPNLFQPYIVEICDSLRGNIFQKFIESDKFTRFCQWKNV
ELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER
IMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKDMRFYAAE
IILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPE
VLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMNVELPDSFTPE
LKSLLEGLLQRDVAKRLGCLGRGASEVKEHVFFKGIDWQQVYLQKYPPPLIPPRGEVNAA
DAFDIGSFDEEDTKGIKLLDSDQELYKNFPLVISERWQQEVAETVYEAVNSDTDKNEARK
RAKNKQQGHEEDYALGKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRVEWRGEGESRQNL
LTMEHIVTVEETQIKDKKCILLRVKGGKQFVLQCESDPEFVQWKKELTEAFTEAQKLLRR
APKVIGKGRTNVVELSKPPLTHRNSNGL

>Takifugu rubripes_ADRBK2(ENSTRUP_47668)
MADLEAVLADVSYLMAMEKSKSTPAARASKKIILPEPSIRSVMQKYLEERDELTFDKIFN
QKIGFLLFKDYCMNEIDEAVPQLKFYEEIKDYEKLDSEEERLSRSRQIYDVYIMKELLSC
SHSFSKKAVDHVQSHLAKKQVPPTLFQPYIVEICDSLRGKIFQKFIESDKFTRFCQWKNV
ELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER
IMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYAAE
IILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPE
VLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMNVELPDSFTAE
LKDLLEGLLQRDVSKRLGCQGQGASEVKEHQFFKGIDWQQVYLQKYSPPLIPPRGEVNAA
DAFDIGSFDEEDTKGIKLLDSDQELYKNFPLVISERWQQEVAETVYEAVNLDTDKNEARK
RAKNKQLGHEEDYALGKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRVEWRGEGESRQNL
LTMEQIVTVEETQIKDKKCILLRIKGGKQFVLQCESDPEFVQWKKELTEAFTEAQKLLRR
APKVIGKGRAGVVELSKPPLTHRNSNGL

>Tetraodon nigroviridis_ADRBK2(ENSTNIP_16581)
MADLEAVLADVSYLMAMEKSKSTPAARASKKIILPEPSIRSVMQKYLEERDELTFDKIFN
QKIGFLLFKDFCMNEIDEAVPQLKFYEEIKDYEKMDSEEERLSRSRQIYDVYIMKELLSC
SHSFSKKAVDHVQSHLAKKQVPPTLFQPYIVEICDSLRGKIFQKFIESDKFTRFCQWKNV
ELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER
IMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLLYHLSQHGVFSDKEMRFYAAE
IILGLVHMHNRFVVYRSGNPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPE
VLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMNVELPETFTAE
LKDLLEGLLQRDVAKRLGCQGQGATEVKEHQFFKGIDWQQVYLQKYSPPLIPPRGEVNAA
DAFDIGSFDEEDTKGIKLLDSDQELYKNFPLVISERWQQEVAETVYEAVNSDTDKNEARK
RAKNKQLGHEEDYALGKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRVEWRGEGESRQNL
LTMEQIVTVEETQIKDKKCILLRIKGGKQFVLQCESDPEFVQWKKELTEAFTEAQKLLRR
APKVIGKSRTGGLDHAKPPLTHRNSNGL

>Ciona intestinalis_(ENSCINP_7015s)
MIDAIEERLKAPPECDQEELNQDLFSECSSAITNYLSGQPFKEFCDSIYFSRFLQWKWLE
RQPVTKNTFRQYRVLGKGGFGEVCACQVRS_SGKMYACKRLEKKRIKKRKGEAMALNEKQI
LESVNSRFVVSLGYAYETKDALNLVLTIMNGGDLKFHIHNMGAPGFSIHRAIFYSAEITC
GLHDLHKQRIVYRDLKPENILLDDHGHIRISDLGLAVRIPSGEKIKGRVGTVGYMAPEVV
RNERYEMSPDWFGLGCIIYEMIAGQAPFRKRKEKVKREEVDRRVKEDTESYDDEKFTEEA
KSICSMLLKKDVKDRLGCRNGSCASDVKAHPFFKNINFKRLETGKAPFGNPPFDKVPFEL
DPHAVYAKDVLDIEQFSTVKGVTIDGKDNDFYAKFSTGSVSIPWQNEMCETSVYKDLNVF
NADGSPTPDLTPYDQQSNPPKKGFFSRLFGRQKQPEGSKPTRRASR

>Ciona intestinalis_(ENSCINP_16461)
MSDTTTGPSMASIVKEGWLQKRGEYIRNWRRRYFVLKTDGSFLGYKDKPDPDNHQEPLNN
FSVLKSQVMRKDQQRENAFVFVVRCLQWTTIIERTFTSTSKVDREEWMKAIEGVSDQLQH
SPEEKSVTEDESKKTSDHKVINTVCENTFNKHANPLIKQPENEFIKPAKSNKTLTDFEFL
EVLGKGTFGKVILVKEKKTEEFHAMKILKKEVIVAKDEVTHTLTENRVLQQTRHPFLTSL
KYSFQTNDYLCFVMEYVNGGEIFFHLSRDRVFSEDRARFYGAEIILALDYLHQQEVIYRD
LKLENLLLDSEGHIKITDFGLCKEEIRFGTTTKTFCGTPEYLAPEVLEDNDYGRSVDWWG
LGVVMYEMMCGRLPFYNRDHDVLFELILMDDLRFPSGLSKEGKSLLSELLNKDPLKRLGS
SQSDAQEVMAHRFFSAVVWKDILEKKVPPPFKPQVSSITDTRYFDKEFTAQPVQLTPPDQ
SSSMDDTNRPHFEAFSYSSSGSHLDKGSRNHR

>Ciona intestinalis_(ENSCINP_2847)
MADLEAVLADVSYLMAMEKSKGAPAARAVKRIQLPDPSIRTLMQKYLTERELINFDEIFN
QEIGYRLFKEFCTQSDLPIPQLLFYEEILTFQSMDLEEERATQAKMMYNQFIMKKLLRHC
THEFSKDALDIVKAKILKNHFPIDLFQVYDKEVRESLKKHFFQLFVESDKFTRYLQWKNL
ELSLHLTMNDFSVHRIIGRGGFGEVYGCRKADTGTMYAMKCLDKKRIKLKQGESLSLNER
KMLQMVDSPFIVCISYAFQSIDKLCFVLDLMNGGDLHYQLTQRGTFTENEVRFYASEILL
GLDHMHSHGIVYRDLKPANILLDEKGHTKISDLGLACDLSRKRPHASVGTHGYIAPEVLT
RGMSYDTGADWFSYGCTVFKLLRGHSPFRNHKTKDKAEIDKMTLTMEVKMPSSFSDEVSD
FLQQLLIKDPKDRLGCRGRAGEELKEHSFFLDVDWDQVQRQKYLPPLTPPRGEVNAADAF
DIGNFDDDETKGIKLTDADQDLYQDFDLVVSSRWQKEICDTVFDMVNHETDKLEAKRKTK
GKALFAEGDCFLHGILYKLGGPLALTTWQKKYFYLYPNRLEWKDYDGSVRQ

>Ciona intestinalis_(ENSCINP_11573)
MPLAPFGNAPFVNSANTQPLTEEVLCLVSEEKNDEQMHEIEIKENTIKGCQKADPSQFEL
LKVLGQGSFGKVFLVRKIVGNDRHQLYAMKVLKKAKLKVRDRVRTKMERNILVDVNHPFI
VKVYYAFQTDGNLYMVLAYLRGGDLFTRLSKELMFTEDDVKIYLAELALALDHLHSLGII
YRDLKPENILLDVDGHIALTDFGLSKESTDGSEKAYSFCGTVEYMAPEVVNRRGHDHSAD
WWSFGVLMYEMLTGQLPFQGRDRKDTMTQILKAKLGMPQFLSPEAQSLLRMLFKRNPANR
LGSGSDGVEEIKRHPFFSGIDWNRLLRKDIDPPFKPSASRAEDATYFDSEFTSRTPRDSP
GVPASAAAQQLFRGFSFVAPIIEEDAVGTGVIGIMVLKFLLNNSPKKFYDEYDVREEIGI
GSYSVCKRCIHKGTKKEYAVKIIFKNKRDCEEEVQILLRYGQHPNIITLKDVFDDGQHVF
LVTELMKGGELLDKILRQKFFTEKEASAVLKTVAKVVVYLHKNGVVHRDLKPSNILYADE
TGNPESLRVCDFGFAKQLRHDNGLLMTPCYTANFVAPEVLKKKGYDEACDIWSLGVLLYT
MLAGYTPFANGPDDTPTDILKRIETGKFNMSGGNWKSVSETAKDLVRRMLHVDPNRRLSA
PQVLMHSFIARPDQLPEFHLNQSKDYKFVKGAMSAMFSAARSHKPLNLNPVGTSLLAQRR
GAKKVTSTAL

>Ciona savignyi_(ENSCSAVP_344)
MHEIEIKENTIKGCQKADPSQFELLKVLGQGSFGKVFLVRKIVGNDRGQLYAMKVLKKAK
LKVRDRVRTKMERNILVDVNHPFIVKVYYAFQTDGNLYMVLAYLRGGDLFTRLSKELMFT
EDDVKIYLAELALSLDHLHSLGIIYRDLKPENILLDVDGHIALTDFGLSKESTEGSEKAY
SFCGTVEYMAPEVVNRRGHDQSADWWSFGVLMYEMLTGQLPFQGRDRKDTMTQILKAKLG
MPQFLSQEAQSLLRMLFKRNPGNRLGSGSDGVEEIKRHPFFNGIDWNRLLRKDIDPPFKP
SVTRAEDAAYFDSEFTSRTPRDSPGVPASAAAQQLFRGFSFVAPIIEEEAHVGAPQDEFM
TSQLNQSPKKFHDEYEEKEEIGIGSYSVCKRCIHKGTKKEYAVKIIFKNKRDCEEEVHIL
LRYGQHPNIITLKDVFDDGQHVFLVTELMKGGELLDKILRQKFFTEKEASAVLKTVTKVV
VYMHKNGVVHRDLKPSNILYADETGNPDSLRVCDFGFAKQLRHDNGLLMTPCYTANFVAP
EVLKKKGYDEACDIWSLGVLLYTMLAGYTPFANGPDDTPTDILKRIETGKFNMSGGNWKS
VSDIAKDLVRRMLHVDPNRRLSAPQVLMHPFIARPDQLPEFHLNQSKDYKFVKGAMSAMF
SAARSHKPLNLNPVGTSLLAQRRGAKKVTSTAL

>Ciona savignyi_(ENSCSAVP_3176)
MADLEAVLADVSYLMAMEKSKGAPAARAVKRIQLPDPSIRTLMYKYLNERGLINFDEIFN
QEIGYRLFKEFCTQSDLPIPQLLFYEEILTYQSLDLEEERATQAKMMYNQCIMKKLPITC
SFFQEFSKDALDKVKSLILQNKFPIDLFQVYDAEVRKSLKHHFFQLFIESDQFTRYLQWK
NLELSLHLTMNDFSVHRIIGRGGFGEVYGCRKADTGTMYAMKCLDKKRIKLKQGESLSLN
ERKMLQMVDSPFIVCISYAFQSVDKLCFVLDLMNGGDLHYQLTQRGTFTENEVRFYASEI
LLGLDHMHSRGIVYRDLKPANILLDEKGHTKISDLGLACDLSKKRPHASVGTHGYIAPEV
LTRGMSYGTGADWFSYGCTVYKLLRGHSPFRNHKTKDKSEIDKMTLTMEVKMPASFTPEV
ADFLQKLLIKDPNERLGCMGRAGEELKEHQFFADVDWEQVQRQKYLPPLTPPRGEVNAAD
AFDIGNFDDDETKGIKLTENDQELYNDFDLVVSTRWQKEIYDTVFDMVNHETDKAETKRK
TKGKALFADKLEGDCLLHGIMYKLGGPLALTTWQKRYCYLYPNRLEWKDYDGSKNLVVFE
SVTMIKEGQAKGMKYCLFISTRESSKDIILRCESKPEFVQWSKDLTKTWCQAKRVMKSGP
KLISMQRS

>Ciona savignyi_(ENSCSAVP_13097)
MAEPSVVKEGWLHKRGEYIRNWRRRYFVLKTDGSFLGYKEKPIPDNHQEPLNNFSVLKSQ
LMRKEHQRENAFVFIVRCLQWTTIIERTFTATSYQDREEWMKAIEGVSDQLQHSPEEKNV
AEDETHKSGDHKLCACNSKPTKLIYRLTLTDFEFLEVLGKGTFGKVILVKEKKTDELYAM
KILKKEVIVAKDEVTHTLTENRVLQQTKHPFFNVSLKYSFQTTDYLCFVMEYVNGGEIFF
HLSRDRVFSEERAKFYGAEIILALDYLHQQEVIYRDLKLENLLLDSDGHIKITDFGLCKE
EIRFGTTTKTFCGTPEYLAPEVVLEDNDYGRSVDWWGLGVVMYEMMCGRLPFYNRDHDIL
FELILMDDLRFPSGLSREGRSLLSELLNKDPQKRLGSSQTDAQEVMAHRFFSNIVWQDIL
DKKAPVPFKPQVTSSTDTRYFDKEFTAQPVQLTPPDQSSSIDDVSRPHFEAFSYSSSGSH

>Ciona savignyi_(ENSCSAVP_19415)
MELENIVANTVYLKAREGGGGKRKGKSKKWREMMKFPHISLTEDLRRTIERDYTSICEEQ
PIGQRLFRLFCETKPELNICRDCLEQMRNYEETLLEDRRQVAQTVFDKYLKDRVRWAGCV
LSCFFGRKYFIHKYFPIEYLFYATKNAITTYLSGQPFKEFCDSIYFSRFLQWKWLERQPV
TKNTFRQYRVLGKGGFGEVCACQVRS_SGKMYACKRLEKKRIKKRKGEAMALNEKQILESV
NSRFVVSLGYAYETKDALNLVLTIMNGGDLKFHIHNMGAPGFSIHRAIFYAAEITCGLHD
LHKQRIVYRDLKPENILLDDHGHIRISDLGLAVRIPSGEKIKGRVGTVGYMAPEVVRNER
YEMSPDWFGLGCIIFEMIAGQAPFRKRKEKVKREEVDRRVKEDTEVYDDEKFTEEAKSIC
SMLLKKDVKDRLGCRNGSCAADVKAHVFFKNINFKRLETGKQPFGNPPFDKPHAVYAKDV
LDIEQFSTVKGVTIDNKDNDFYAKFSTGSVSIPWQNEMCDTSVYKDLCVFNMDGTPTPDL
IPYDQQSNPPKKGLFSRLFGRQ

>Drosophila melanogaster_(FBpp0082682)
MNYLPFVLQRRSTVVASAPAPGSASRIPESPTTTGSNIINIIYSQSTHPNSSPTSGSAEK
FSWQQSWPSRTSAAPTHDSGTMSINTTFDLSSPSVTSGHALTEQTQVVKEGWLMKRGEHI
KNWRQRYFVLHSDGRLMGYRSKPADSASTPSDFLLNNFTVRGCQIMTVDRPKPFTFIIRG
LQWTTVIERTFAVESELERQQWTEAIRNVSSRLIDVGEVAMTPSEQTDMTDVDMATIAED
ELSEQFSVQGTTCNSSGVKKVTLENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKE
VIIQKDEVAHTLTESRVLKSTNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERI
FTEDRTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRT
TKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEE
VKFPRNITDEAKNLLAGLLAKDPKKRLGGGKDDVKEIQAHPFFASINWTDLVLKKIPPPF
KPQVTSDTDTRYFDKEFTGESVELTPPDPTGPLGSIAEEPLFPQFSYQGDMASTLGTSSH
ISTSTSLASMQ

>Drosophila melanogaster_(FBpp0085149)
MELENIVANTVYLKAREGGSDSNKGKSKKWRKILQFPHISQCINLKDKLDISYGYVIDQQ
PIGRELFRLFCENKRPVYFRYITFLDEVVKYEIEYISNRIFIGHDIGRRFLDVEAQLELR
NGSGGDALDAETQEELLLNSSNANPTETAETEHCNNTTANNCNNINNSNNSQHSSDINHK
KLDTRNHNGDDATGNGSSHQDDGDESVKCQEGHDDAEKGGGGEGGGGGKCVPVGGYPDEL
VLDVLNDDLIAQVRNKLNSGGKDIFAQCVNAVKAFLAGEPFREFESSMYFHRYLQWKWLE
AQPITYKTFRMYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGESMVLIEKQI
LQKINSPFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGGEPGFELERARFYAAEVA
CGLQHLHKQGIVYRDCKPENILLDDHGHVRISDLGLAVEIPEGEMVRGRVGTVGYMAPEV
IDNEKYAFSPDWFSFGCLLYEMIEGQAPFRMRKEKVKREEVDRRVKEDPEKYSSKFNDEA
KSMCQQLLAKSIKQRLGCRNGRMGGQDVMAHPFFHSTQLNWRRLEAGMLEPPFVPDPHAV
YAKDVLDIEQFSTVKGVNIDESDTNFYTKFNTGSVSISWQNEMMETECFRELNVFGPEEC
PTPDLQINAAPEPDKAGCFPFRRKKKQPARTQPIPIPEHLLTTSHSVSSTTVES