>Homo sapiens_ADRA1A(ENSP_369960)
MVFLSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV
THYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCII
SIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINE
EPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN
APAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPD
FKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQSSKHALGYTL
HPPSQAVEGQHKDMVRIPVGSRETFYRISKTDGVCEWKFFSSMPRGSARITVSKDQSSCT
TARTKSRSVTRLECSGMILAHCNLRLPGSRDSPASASQAAGTTGMCHQADATRPS
>Mus musculus_ADRA1A(ENSMUSP_124570)
MVLLSENASEGSNCTHPPAQVNISKAILLGVILGGLIIFGVLGNILVILSVACHRHLHSV
THYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMGLCII
SIDRYIGVSYPLRYPTIVTQRRGVRALLCVWALSLVISIGPLFGWRQQAPEDETICQINE
EPGYVLFSALGSFYVPLTIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN
VPAEGSGVSSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPN
FKPPETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRRQSSKHALGYTL
HPPSQAVEGQHRGMVRIPVGSGETFYKISKTDGVREWKFFSSMPQGSARITMPKDQSACT
TARVRSKSFLQVCCCVGSSTPRPEENHQVPTIKIHTISLGENGEEV
>Monodelphis domestica_ADRA1A(ENSMODP_20809)
MVFFPENASDSSNCTHAQEPVNISKAILLGVILGSLILFGVLGNILVILSVACHRHLQSV
THYYIVNLAVADLLLTSTVLPFSAILEILGYWAFGRIFCNIWAAVDVLCCTASIMGLCII
SIDRYIGVSYPLRYPTIVTQKRGLLALMCVWALSLTISIGPLFGWKEQPPEDETICQITE
EPGYVLFSALGSFYIPLAIILVMYCRVYVVAKRESKGLKHGLKTDKSDSEQVTLRIHRKN
IPSASSSGSSSKNKTHFSVRLLKFSREKKAAKTLGIVVGCFILCWLPFFLVMPIGSFFPE
SKPSDTVFKIAFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRAQCLRRKQSTKHAIGYTL
NPPSHAIGEHKDLVRIPVGSGETFYKISKSEGVCEWKFFSSTSSGPTRNAVTHDQSTCTS
ARVRSKSFLRVCCCVGSSGPAIQENRQLPTIKIHTISLSENGEEVS
>Gallus gallus_ADRA1A(ENSGALP_638)
MVFLPGNSSNCSNCTYSAEPVNISKAILLGVILGGLIIFGVLGNILVILSVACHRHLQSV
THYYIINLAVADLLLTSTVLPFSATMEILGYWAFGRIFCNIWAAVDVLCCTASIMSLCII
SIDRYIGVSYPLRYPSIVTEKRGLLALLCVWALSLVISIGPLFGWKEPAPEDETICQITE
EPGYVLFSALGSFYLPLTIILVMYCRVYVVAKRENKGLRSGLKMEKSRSEAVTLRIHRKN
VPENSGATASSKSKHHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFVVMPLGSFFPT
IKPPDTLFKITFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRAQCLPRKHAAKKQSPSFN
LNHPSNQSMGGGKGVVRIPVGSGETFYKISKSDGVCEWKIFSAVQSVPTKSAIPKDKSSC
TAAKVKSKGFLQECCCAGTSGNTVHENCKVPTIKIHTMSLSESGEDV
>Pelodiscus sinensis_ADRA1A(ENSPSIP_18062)
MVFLPGNSTDCSNCTQTVGITDNLKAILLGVILGGLIVFGVLGNILVILSVACHRHLQSV
THYYIINLAVADFLLTSTVLPFSATFEILGYWVFGRIFCNIWAAVDVLCCTASIMSLCII
SIDRYIGVSYPLRYPAIMTEKRGLMALLCVWALSLVISIGPLFGWKEPAPEDETICQITE
EPGYVLFSAFGSFYLPLTIILVMYCRVYVVAKRESKGLTSGLKTEKSHSEEVTLRIHCKN
TSTGSGSTPSTKNKTHFSVRLLKFSREKKAAKTLGIVVGCFILCWLPFFIVMPIGVFFPA
IKPSKTVFKITFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRAQCLSKKQAASKHSLSFN
LNHPASHSMDSTKNVVRIPVGSGETFYRISKSEGVCEWKIFSTVQSMATKSAISKDKSSC
TRAKVKSKGFLRTCCCAGTSGSVGRDNHNVPTIKIHTISVSENGEDV
>Xenopus tropicalis_ADRA1A(ENSXETP_63387)
MVILYENNTVESIQLCLNCTHPGATINISKAIVVGVIFGVFITFGVLGNILVILSVACHR
HLQTVTHYFIANLAVADLLLMSMVLPFSATFEIQGYWLFGRIFCNIWAAVDVLCCTASIM
SLCAISIDRYIGVSYPLRYPSIMTEKRGVLALLCIWVLSLVISIGPLFGWKQPAPEDDKI
CEITKEPGYALFSAFGSFYLPLSIILVMYFRVYIVAKRESKVLTSGMKLEKSDSEEVTLR
IHRKSTPESIGSTSSSKQKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIA
GSIYPPANSSDTIFKITFWLGYFNSCINPVIYPCSSPEFRKAFQNILHARCSHRRQAASK
YSSGFLLNSPVHRSSEENKNVVRIPVGSGEMFYRISKSDEGCEWKYFTPLPSPATPYGTP
RDFANCSSARVSSKSFLRTCCCVGTQQTRSCHDVPTIKIHTISVSENGEAV
>Danio rerio_ADRA1Aa(ENSDARP_35603)
MVFGNAQNCSNCSQVLVPELNVMKAVALGVVLAIFIVFGVLGNILVILSVACHRNLRTVT
HYFIVNLAVADLLLSSTVLPFSTVFEMLGRWIFGRPFCDVWAAMDVLCCTASIMSLCVIS
VDRYIGVSYPLQYPSIVTERRALLALIALWVLSITISIGPLFGWKEPAPDDESICKITEE
PGYAIFSALGSFYLPLVVILSMYCRVYVVARRETRGLISGQKTEKSDHAETVTLRIHRGN
MTVSEDEALRNRTHFALRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVLPIDLGSIFPT
YRPSDTVFKITFWLGYFNSCINPIIYPCSSQEFKKAFLSVLGARCLRKRSTPSHTLYQSH
SPRHGQSQILGLSSRDNPSRLSPSSSIALSRSPSSRDGRDWQAPSRTSSVGTTGVSTGVS
VGAKMAGMCGKNLLRTCCCVRADSPQPEPPAQNSLPVIKIHQLSLCEDGDAV
>Homo sapiens_ADRA1B(ENSP_306662)
MNPDLDTGHNTSAPAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAI
VGNILVILSVACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDI
WAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGP
LLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAG
VMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVV
GMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFV
RILGCQCRGRGRRRRRRRRRLGGCAYTYRPWTRGGSLERSQSRKDSLDDSGSCLSGSQRT
LPSASPSPGYLGRGAPPPVELCAFPEWKAPGALLSLPAPEPPGRRGRHDSGPLFTFKLLT
EPESPGTDGGASNGGCEAAADVANGQPGFKSNMPLAPGQF
>Mus musculus_ADRA1B(ENSMUSP_702)
MNPDLDTGHNTSAPAHWGELKDANFTGPNQTSSNSTLPQLDVTRAISVGLVLGAFILFAI
VGNILVILSVACNRHLRTPTNYFIVNLAIADLLLSFTVLPFSATLEVLGYWVLGRIFCDI
WAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGP
LLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAG
VMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVV
GMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFM
RILGCQCRGGRRRRRRRRLGGCAYTYRPWTRGGSLERSQSRKDSLDDSGSCMSGSQRTLP
SASPSPGYLGRGTQPPVELCAFPEWKPGALLSLPEPPGRRGRLDSGPLFTFKLLGEPESP
GTEGDASNGGCDTTTDLANGQPGFKSNMPLAPGHF
>Monodelphis domestica_ADRA1B(ENSMODP_9988)
MNPHLDVSHNISAPAYWEEPSVGNLTGPNQTSSYSTPPELDIRRAISVGIVLGAFILFAI
VGNILVILSVACNRHLRTPTNYFIVNLAIADLLLSFTVLPFSAALEVLGYWVLGRIFCDI
WAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRKKAILALLSVWVLSMVISIGP
LLGWKEPAPKDEKECGVTEEPFYALFSSLGSFYIPLTVILVMYCRVYIVAKRTTKNLEAG
VMKEMSNSKELTLRIHSKNFHEDALSSTKVKGHNPRNSIAVKLFKFSREKKAAKTLGIVV
GMFILCWLPFFIILPLGSLFATLKPPDTVFKVVFWLGYFNSCINPIIYPCSSKEFKRAFL
RILKCQCHRRNRLGWWNYNYRAWNRGSFEQSRKDSLDDSGSCLSGSQRTLNSATPSPGYL
SKVTHPQVEMYTFSEWKSSGTFLSPPHPEPPGRHRDTGHLFTLKYLAEHEGHPGLDSNGG
CEVAANMANGQAGFKKNMPLGPSQF
>Gallus gallus_ADRA1B(ENSGALP_2155)
NLSANSSNETTSNLDSPTLDISRAITVGLILGAFILFAIIGNILVILSVACNRHLRIPTN
YFIINLAIADLLLSFTVLPFSATLEILGYWVLGRIFCDIWAAVDVLCCTASILSLCAISI
DRYIGVRYSLQYPTLVTRRRAILALLGVWVLSMVISIGPLLGWKEPAPKDDKECRITEEP
FYALFSSLGSFYIPLIVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHYRNIH
EDTLNSNKSKGHNSRNSLALKLLKFSREKKAAKTLGIVVGMFILCWLPFFIVLPLGSLFS
ALKPPEIVFKVIFWLGYFNSCLNPIIYPCSSKEFKRAFIQILKCQCHRRKQSGWWAYSYR
NWNRCSFEHPRKDSLEDSGSFLSGSQRTLSSASPSPGYLSKITHPHMEMCTFQEWKNPSS
FLSPLQEGSRQKDPCQFFTFNLLTERNGHIAASSQASSNGDHEDIFDTVNGKTDCRTNIM
LE
>Danio rerio_ADRA1Ba(ENSDARP_21131)
SDVSNSNSSGNGTAPSSFSLSRALPLGMVLGAFIVFAIVGNILVILSVVCNRHLRIPTNY
FIINLAMADLLLSTTVLPVSATREILNYWVFGRIFCDIWAAVDVLCCTASIMSLCVISID
RYIGVRYPLQYPSIVTEKRALLAMLGVWVLAFVISIGPLLGWKEPPSEDDTVCLITEEPF
YALFSSLGSFYIPLAVILAMYCRVYIVAKRTTKNLEAGVMKERMDSNELTLRIHYKGSQT
QEDCSKGHLRSSLTVKLLKFSREKKAAKTLGVVVGMFILCWLPFFLALPIGSFNTSLRPP
ETFFKVIFWLGYFNSCLNPIIYPCYSREFKQAFIRILRCQCQQKKQQGWRAYNYRVPNAN
HVYSDTSSICMNGSLQTLAPSQPSPTLFSRVVGSRPASGLLPGWGPCTSSSSSSLSGSPF
PGMMRSGSQATSPCKSNRMALLFPNGQNGK
>Danio rerio_ADRA1Bb(ENSDARP_60350)
MNPQNEYAVTRSWGSTILDAFEGSAVFPNFSLKLNGTGLEPLLLSRAVPLGLVLGFFITF
AIAGNILVILSVVCNRHLRSPTNYFIVNLAIADLLLGTTVLPVSATLEVVGHWVFGRIFC
DVWAAVDVLCCTASIMSLCVISIDRYIGVSHPLQYPNIVTGRRALLAMLGVWVLSLVISI
GPLLGWKEPPSPDDTVCAINEEPFYALFSSLGSFYIPLIVILVMYCRVYVVAKMTTKNLE
AGVKTESMNSGEITLRIHRGSQVHEDAGKSRAHQARNSLTVKLLKFSREKKAAKTLGVVV
GMFTLCWLPFFLTLPIVSFNTSLRPPETVSSIIFWLGYFNSCLNPIIYPCYSREFKLAFI
RILKCRCHRRRRPGWRAYNYRGSQINSFYSRQDSRDSVNYGSYLNGSQRTLSSSSPSPSY
HTKGLSHFQEDGPRLGRSRTPSVLSESILDHHLEPVEEDPRQTVSIQDHAGVSELASKAS
E
>Takifugu rubripes_ADRA1Ba(ENSTRUP_2409)
MSLSTDNVTFLWKNDSTQLDNASSRVNFSSSAGGNHTALNEVRLTRAIPLGLVLGAFIVF
AIAGNILVILSVVCNRHLRTPTNYFIINLAIADLLLSTTVLPVSATLEILNYWVFGRIFC
DIWAAVDVLCCTASIMSLCVISIDRYIGVSHPLQYPGIVTEKRALLAMLGVWALSVVISI
GPLFGWKQPPSPDDTECPITEEPFYALFSSLGSFYIPLVVILAMYCRVYIVAKRTTKNLE
AGVMRERMNSSELTLRIHKGCQVHEEPGHSGTGKGRAHQARSSLTVKLLKFSREKKAAKT
LGVVVGMFTLCWLPFFLALPIGSFNVNLRPPEILFKVIFWLGYFNSCLNPIIYPCYNREF
KLAFIRILRCQCHQRKRPGFKAYNYRTSNISASGHSRKGSADHNSSCLNGSQRTLPSSAS
PSPSYLSRGLPT
>Takifugu rubripes_ADRA1Bb(ENSTRUP_20319)
RLSSAFGMSLWTNRSSAGPMGSNSSINGSQPGAAPLDLSRAVPVGMVLAFFIMFAIVGNI
LVILAVVCNRHLRIPTNYFIINLAIADLLLGTTVLPVSATLEVLDYWVFGRIFCDIWAAV
DVLCCTASIMSLCAISIDRYIGVRYPLQYPMIVTEQRALLAMLGVWILSIVISIGPLLGW
KQPPSQDDTVCVITQEPFYALFSSLGSFYIPLAVILAMYFRVYIVAKRTTKNLEAGVMKE
SQENSNELTLRIHCRNQQIQDLCPSSKGGSGGSSAGRSTLTVKLLKFSREKKAAKTLGVV
VGMFILCWLPFFLALPIGSFNPSLRPPETFFKVIFWLGYFNSCLNPIIYPCYSREFKQAF
IRILQCQWKRKRQRWQAYPNYRRHQGSNNSSFLNSSQQALSSVSPSTQYVTSRPHP
>Tetraodon nigroviridis_ADRA1B(ENSTNIP_7306)
MSLGTDNVTFLWKNDSTELDNASSRVNFSSGGNHSALSELRLSRAIPLGLVLGAFIVFAI
AGNILVILSVVCNRHLRTPTNYFIINLAIADLLLSTTVLPVSATLEILNYWVFGRIFCDI
WAAVDVLCCTASIMSLCVISIDRYIGVSHPLQYPGIVTEKRALLAMLGVWALSVVISIGP
LFGWKQPPSPDDTVCPITEEPFYALFSSLGSFYIPLVVILAMYCRVYIVAKRTTKNLEAG
VMRERMNSSELTLRIHKGSQVNEESGHAATATGTGTGKGRAHQARSSLTVKLLKFSREKK
AAKTLGVVVGMFTLCWLPFFLALPIGSFNVNLRPPEILFKVIFWLGYFNSCLNPIIYPCY
SREFKLAFIRILRCRCQQRKRPGFQAYSHRSSNISSSGHSRKGSADHNSGCLNGSQRTLP
SSASPSPSYLGGALPP
>Oryzias latipes_ADRA1B(ENSORLP_6864) TNNVTNLWKNGSSELNWETLQINFTNGSGGEHREAGKVDLTRAIVLALVLGAFIVFAIAG
NILVILSVVCNRHLRTPTNYFIINLAMADLLLGTTVLPVSATKEILNYWVFGRIFCDIWA
ALDVLCCTASIMSLCVISIDRYIGVSHPLQYPGIVTEKRALLAMLGVWVLSVVISIGPLL
GWKQPPSDDDMECLITEEPFYALFSSLGSFYIPLAVILAMYCRVYIVAKRTTRNLEAGVM
RERMNTSELTLRIHKGSQMHEEPGTSNAGKGRGHQARSSLTVKLLKFSREKKAAKTLGVV
VGMFILCWLPFFLTLPLGSFNENLRPPELLFRVIFWLGYFNSCLNPIIYPCYSREFKLAF
IRILRCQCHQQKRPSWRAYNYRSSNFSSSGNSRKSSTDHTSSWLNGSQGTLPSSASPSPS
YLSSGLPP
>Homo sapiens_ADRA1D(ENSP_368766)
MTFRDLLSVSFEGPRPDSSAGGSSAGGGGGSAGGAAPSEGPAVGGVPGGAGGGGGVVGAG
SGEDNRSSAGEPGSAGAGGDVNGTAAVGGLVVSAQGVGVGVFLAAFILMAVAGNLLVILS
VACNRHLQTVTNYFIVNLAVADLLLSATVLPFSATMEVLGFWAFGRAFCDVWAAVDVLCC
TASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWVVALVVSVGPLLGWKEPVP
PDERFCGITEEAGYAVFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKAS
EVVLRIHCRGAATGADGAHGMRSAKGHTFRSSLSVRLLKFSREKKAAKTLAIVVGVFVLC
WFPFFFVLPLGSLFPQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQ
CRRRRRRRPLWRVYGHHWRASTSGLRQDCAPSSGDAPPGAPLALTALPDPDPEPPGTPEM
QAPVASRRKPPSAFREWRLLGPFRRPTTQLRAKVSSLSHKIRAGGAQRAEAACAQRSEVE
AVSLGVPHEVAEGATCQAYELADYSNLRETDI
>Gorilla gorilla_ADRA1D(ENSGGOP_10407)
MTFRDLLSVSFEGPRPDSSAGGSSAGGGGGSAGGAAPSEGPAVGGVPGGAGGGGGGVVAV
GGLVVSAQGVGVGVFLAAFILMAVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLLLSA
TVLPFSATMEVLGFWAFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAI
MTERKAAAILALLWVVALVVSVGPLLGWKEPVPPDERFCGITEEAGYAVFSSVCSFYLPM
AVIVVMYCRVYVVARSTTRSLEAGVKRERGKASEVVLRIHCRGAATGADGAHGMRSAKGH
TFRSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQLKPSEGVFKVI
FWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRRRRPLWRVYGHHWRASTSGLRQ
DCAPSSGDAPPGAPLALTALPDPDPERKPPSAFREWRLLGPFRRPTTQLRAKVSSLSHKI
RAGGAQRAEAACAQRSEVEAVSLGVPHEVAEGATCQAYELADYSNLRETDI
>Mus musculus_ADRA1D(ENSMUSP_99473)
MTFRDILSVTFEGPRASSSTGGSGAGGGAGTVGPEGPAVGGVPGATGGSAVVGTGSGEDN
QSSTAEAGAAASGEVNGSAAVGGLVVSAQGVGVGVFLAAFILTAVAGNLLVILSVACNRH
LQTVTNYFIVNLAVADLLLSAAVLPFSATMEVLGFWAFGRTFCDVWAAVDVLCCTASILS
LCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWAVALVVSVGPLLGWKEPVPPDERFC
GITEEVGYAIFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGIKREPGKASEVVLRI
HCRGAATSAKGNPGTQSSKGHTLRSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFF
VLPLGSLFPQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRR
RLWRVYGHHWRASTGDPRSDCAPSPRIAPPGAPLALTAHPGPGSVDTPEAQASVSGRRKP
ASALREWRLLGPLQRPTTQLRAKVSSLSHKFRSGGARRAETACALRSEVEAVSLNVPQDG
AEAVICQAYEPGDLSNLRETDI
>Canis familiaris_ADRA1D(ENSCAFP_9109)
MTFRDLLIVSFEGPRPDGSAGGSSAGGCGGGAGGAAASEGPAVGGVPGAALGGGGGVMGA
CVGQDNRSSAGEPGGAGTGGEVNGTAAVWGLVVSAQGVGVGVFLAAFILTAVAGNLLVIL
SVACNRHLQTVTNYFIVNLAVADLLLSATVLPFSATMEVLGFWAFGRAFCDVWAAVDVLC
CTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWAVALVVSVGPLLGWKEPV
PPDERFCGITEEAGYAVFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKA
SEVVLRIHCRGASAADGAHGPRSAKGHTFRSSLSVRLLKFSREKKAAKTLAIVVGVFVLC
WFPFFFVLPLG
>Equus caballus_ADRA1D(ENSECAP_3536)
VGVGVFLAAFILTAVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLLLSATVLPFSATM
EVLGFWAFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAI
LALLWAVALVVSVGPLLGWKEPVPPDERFCGITEEAGYAVFSSVCSFYLPMAVIVVMYCR
VYVVARSTTRSLEAGVKRERGKASEVVLRIHCRGASLGADGAHGMRSAKGHTFRSSLSVR
LLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGE
>Gallus gallus_ADRA1D(ENSGALP_25693)
MTFPELSNGSLSENRTGQGSQSGANRSWGLQGEESPEGNGTTLPFALDVQAVGVGVFLAV
FILSAIVGNILVILSVACNRHLQTVTNYFIVNLAIADLLLSTTVLPFSATLEVLGFWVFG
RIFCNIWAAVDVLCCSASIMSLCIISVDRYIGVKYSLKYPTIMTERKAGVILVVVWLSSM
VISIGPLLGWKEPPPPDESICSITEEPGYALFSSLFSFYLPLMVILVMYFRIYVVARRTT
RSLEAGVKKERNKSMEVVLRIHCRSVLEEPLSSTQSKGHNFRSSLSVRLLKFSREKKAAK
TLAIVVGVFILCWFPFFFVLPFGSFFPSLKPSEMVFKVIFWLGYFNSCVNPIIYPCSSKE
FKRAFIRLLKCQCHRRRRPIWRVYDHHWRGASVNSSVQDSETDLRPRISTLNSSFIFNSS
LQERAGKRRTLSFKGWKMLTPFQKPASAQLKEKMNSLSNKIRGGSSKGGVTATYKTEVES
VSIGIPHDFMETIDYQTYDLTDCCGLRETDI
>Anolis carolinensis_ADRA1D(ENSACAP_94)
MTFSDRINASLNGNHSGEAGGINGTLPSGGEEDVQANNSTSLALKLTLQSVSVGVFLALF
ILSAIVGNILVILSVACNRHLQTVTNYFIINLAIADLLLSTTVLPFSATLEVLEDLWVFG
RIFCDIWAAVDVLCCTASIMSLCIISVDRYIGVKYSLKYPTIMTEKKAVIIMVAVWISSM
VISIGPLLGWKEAPPENDQHCNITEEPGYAIFSSLFSFYLPLAVILVMYFNIYVVARRTT
KSLEAGVKKERSKSMEVVLRIHCRSVVEDSQASTKNKGHTFRSSLSVRLLKFSREKKAAK
TLAIVVGVFILCWLPFFFVLSFGSYFPSVKPEGMSFKIIFWLGYFNSCVNPIIYPCSSKE
FKRAFIRLLKCQCRRRRRPIWRVYDNHWRGASVNGSGQDSERDLQSRVSTTNGSFILNSS
SLESSSKRRTLNFKRWRMFSPFQKPTQLKEKMNSLSNKIRGGSIKGGVSASYKTEVESVS
IGIPNEFMECIDYQVYDDLTDSESSGLKETDI
>Takifugu rubripes_ADRA1(ENSTRUP_39360)
QLSPAGTKVISINLLLLNRCPRCFLSSPCWIKRLGFVLSAFILVAIVGNILVILSVVCNK
HLQTVTNFFIVNLAMADLLLSIIVLPFSASLEVLGCWVFGRVFCNIWAAVDVLCCTASIL
SLCIISVDRYIGVKHCLKYPCIMTERKAVAILAVVWLSSSVISVGPLLGWKEPQPVDESI
CRITEEPGYALFSSLFSFYLPLMVILIMYFRVYVVARRTSSSLEAGMKRERNNSMEVVLR
MRLMKFSRERKAAKTLAIVVGMFILCWLPFFLFLPIALKPSETVFKVIFWLGYFNSCINP
IIYPCSSKEFQRAFIRLL
>Oryzias latipes_ADRA1D(ENSORLP_7612)
FTMDPQVVGVGIFLSVFILVAIVGNILVILSVVCNKQLQTVTNFFIVNLAIADLLVSIIV
LPFSASLEVLGCWMFGRVFCNVWAAVDVLCCTASILSLCMISIDRYIGVKHCLKYPSIMT
ERKAVAILMLVWVSSLVISVGPLLGWKEPPPVDESICRITEEPGYALFSSLFSFYLPLLV
ILIMYFRVYVVARRTTKSLEAGVKRERDKSVEVVLRIHCRSVLGDARPASSKSSKNHPFR
SSLSVRLMKFSREKKAAKTLAVVVGMFIVCWLPFFLFLPIGM
>Homo sapiens_ADRA2A(ENSP_280155)
MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLML
LTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAW
CEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVIS
FPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKR
RTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGP
RDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTP
AAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPR
TLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
>Mus musculus_ADRA2A(ENSMUSP_36203)
MFRQEQPLAEGSFAPMGSLQPDAGNSSWNGTEAPGGGTRATPYSLQVTLTLVCLAGLLML
FTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKVW
CEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVIS
FPPLISIEKKGAGGGQQPAEPSCKINDQKWYVISSSIGSFFAPCLIMILVYVRIYQIAKR
RTRVPPSRRGPDACSAPPGGADRRPNGLGPERGAGPTGAEAEPLPTQLNGAPGEPAPAGP
RDGDALDLEESSSSEHAERPPGPRRPDRGPRAKGKTRASQVKPGDSLPRRGPGAAGPGAS
GSGHGEERGGGAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLIAVGCPVPS
QLFNFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
>Monodelphis domestica_ADRA2A(ENSMODP_12944)
MLHQEHPLAEGSFAPMGSLQPDSGNGSLNGTEPGGGSRETPYSLQVTLTLVSLAGLLMLL
TVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKVWC
EIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIFTVWVISAVISF
PPLISIEKKGGDKQVEPLCDINDQKWYIISSSIGSFFAPCLIMILVYVRIYQIAKRRTRV
PPSRRSDGCEGAERRPNGLADPGRGEGQPLPAKLNGTGDPVPAEREVNGLDLEESSSSEH
PEQTPGPPGPRKGERGLRGKNKTKMSQVKPGDSLPRRGGEEERGAKASRWRGRQNREKRF
TFVLAVVIGVFVVCWFPFFFTYTLTAVCCSVPPTLFKFFFWFGYCNSSLNPVIYTIFNHD
FRRAFKKILCRVDRKRIV
>Gallus gallus_ADRA2A(ENSGALP_38251)
MEYQRQLEEEEGYPPSGANGTFNDSGAGLGWSMPYPLHTTVTLISLVGLLMLFTVFGNVL
VIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKVWCEIYLALD
VLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKCIIFIVWVISAVISFPPLISIE
KKSGQQVDQWAAGCKINDEKWYIISSSIGSFFTPCLIMILVYVRIYQIAKRRTRVPLNKR
PERPEKKQNGLADKEDLPASAQLNGEKAAGAGDGQEGEVNGIDMEETSSSEHQENNQPKK
SERPLRGKTKTKLSQIKPGDTLPRKTEEERNTKGSRWRGRQNREKRFTFVLAVVIGVFVI
CWFPFFFTYTLTAVCKSCSVPPTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKRILCR
IERKRIV
>Anolis carolinensis_ADRA2A(ENSACAP_15578)
MFQAEVAFVGREGGFSGVAHLRSGHPPLPMEGNASLNGSQGGTREGPFSLHVTLALISLA
TLLMLVIIFGNVLVIIAIFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGQWS
FGKVWCEIYTALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKSIIFLVWVI
SAIISFPPLISIMKQGEPEAPPGEPTESKAGGKEPTCSINKETWYIISSSIGSFFAPCLI
MVLVYVRIYQIAKRRTRVPPGDRQEVAERRQNGLSGKEDVTAASKLNGEKVAVAGGSQDR
EEVNGIDLEDTSSSEHNESHEPKKQEKPPRGKGKTKLSQIKPGDVLPSQAEEERNAKASR
WRGRQNREKRFTFVLAVVIGVFVICWFPFFFTYTLTAVCESCFVPETLFKFFFWCGYCNS
SLNPVIYTIFNHDFRRAFKKILCRLDRKRIG
>Danio rerio_ADRA2Aa(ENSDARP_59868)
MICGANATNGTNATKEYTLLVALPLSVAVGLLILLIIFGNVLVIIAVFTSRALRAPQNLF
LVSLASADILVATLVMPFSLANELMGMWTFGGVWCEIYLALDVLFCTASITHLCAISLDR
YWSITQAIEYNLKRTPQRIKRIIFIVWIIAAVISCPPLITMKKSEGDICDINKEKWYIVS
SCIGSFFLPCIIMVLVYIRIYQIAKKRTRAPPGDHRKNEVGKKENDPHEKLNGIQNAEPD
DKDEINGVDMEESSSSDHKVSNPCSLKKKSSKGKTKLSQIKPGDGDKTEACQTTKASRWK
GRQNREKRFTFVLAVVIGVFVICWFPFFFTYTFTAFCDCCVPETLFKFFFWFGYCNSSLN
PIIYTIFNNDFRRSFKKILCRRDKRRVV
>Takifugu rubripes_ADRA2Ab(ENSTRUP_8423)
AMAPDNQTNRTVGEALPYSLQMSVPLTVLVGIMILLTVFGNVLVVIAVFTSRALRAPQNL
FLVSLASADILVATLVMPFSLANELMGYWYFGEVWCEIYLALDVLFCTASIAHLCAISLD
RYWSITQAIEYNLKRTPRRIKCIIFIVWVMAAVISFPPLITMEKENGKEEPACKINDKKW
YVISSCIGSFFLPCLIMVLVYVRIYQIAKKRTRAPPGDRKPRPAAKTATVDVADRKENGL
GGAELKENPGGPQEKGQANGVDLEESSSSDHKVDMACSIKKKTPKGKTRLSQIKPGEDQA
PTRAPSTKASRWKGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYMLRTLCESCPVPDTLF
KFFFWFGYCNSALNPIIYTIFNNDFRRSFKKILCRRDTRRYV
>Oryzias latipes_ADRA2Aa(ENSORLP_19201)
INNMDYYHSITNIVVDMNLSDRRRRLTMRSSSPAEPRSSRLQVALPLSVLVGVMISLIVF
GNVLVVIAVFTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMGFWYFGKVWCEIY
LALDVLFCTASIAHLCAISLDRYWSITQAIEYNLKRTPRRIKSIIVIVWVIAAVISFPPL
ITMEKENGSESPVCKINDEKWYVISSCIGSFFLPCIIMVLVYVRIYQIAKKRTRAPPGDR
QQKGLSGPGAAAAGQRENGVGEPDDGLCHEKLNGEQDVELKEGVERGADEAKVEVNGGDM
EESSSSDHKADHPCSIPKKSAKGKTRLSQVKPGDADPQRRAQSAKASRWKGRQNREKRFT
FVLAVVIGVFVVCWFPFFFTYMLKTLCSSCYVPTALFNFFFWFGYCNSALNPIIYTIFNH
DFRRAFKKILCRERRKY
>Homo sapiens_ADRA2B(ENSP_387281)
MDHQDPYSVQATAAIAAAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADIL
VATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEY
NSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPQPRGRPQCKLNQEAWYILASSIGS
FFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGESKQPRPDHGGALASAKLPALASV
ASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAALPNSGQGQKEGVCGASPEDEAEEE
EEEEEECEPQAVPVSPASACSPPLQQPQGSRVLATLRGQVLLGRGVGAIGGQWWRRRAQL
TREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAICPKHCKVPHGLFQFFFWIGYCNSSLNP
VIYTIFNQDFRRAFRRILCRPWTQTAW
>Mus musculus_ADRA2B(ENSMUSP_71798)
MVHQEPYSVQATAAIASAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADIL
VATLIIPFSLANELLGYWYFWRAWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEY
NSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQRPEPHGLPQCELNQEAWYILASSIGS
FFAPCLIMILVYLRIYVIAKRSHCRGLGAKRGSGEGESKKPHPAAGGVPASAKVPTLVSP
LSSVGEANGHPKPPREKEEGETPEDPEARALPPNWSALPRSVQDQKKGTSGATAEKGAEE
DEEEVEECEPQTLPASPASVFNPPLQQPQTSRVLATLRGQVLLSKNVGVASGQWWRRRTQ
LSREKRFTFVLAVVIGVFVVCWFPFFFSYSLGAICPQHCKVPHGLFQFFFWIGYCNSSLN
PVIYTIFNQDFRRAFRRILCRQWTQTGW
>Xenopus tropicalis_ADRA2B(ENSXETP_9433)
NPVLQKRVSCVGCPVNTSTMVAPLSYSIQATAVIAAIITFLVLFTIFGNVLVIIAVLTSR
SLKAPQNLFLVSLAAADILVATLIIPFSLANELMGYWYFGKTWCEMYLALDVLFCTSSIV
HLCAISLDRYWSVSQAIEYNSKRTPKRIKCIILIVWTLAALISLPPLIYKGKSKDQNAKP
ECKLNEEPWYILSSSICSFFAPCLIMILVYLRIYLIAKRRNRKNSTDKKLKKMAPGLFSR
TNKHSLNSSHTQTQCGIISSQEKTGLALDDLHCGVPVLSSTREERNGHSESFGLQPQGEN
LKHTNGCEPAVMDTVATVKGVMLMPKGAKDSDLSSAKKKSYINREKRFTFVLAVVIGVFV
LCWFPFFFTYSLGAICTELCYIPDSVFQFFFWIGYCNSSLNPVIYTIFNQDFRKAFRRIL
CSHWSQTTW
>Danio rerio_ADRA2B(ENSDARP_110714)
MDSPCPVAVGLPGHTNGTGGTSSPTCNQSMIKLAPYSPEATAAFATAITLMMLITIVGNI
LVIIAVLTSRSLRGPQNLFLVSLAAADILVATLIIPFSLANELMGYWYFRSVWCEIYLAL
DVLFCTSSIVHLCAISLDRYMSISRAVTYGPKRTPKRIKCAILVVWLISAVISFPPLLSM
NKNKGGGESGALPQCQLNDERWYILYSTIGSFFAPCLIMILVYMRIYQIAKQRTRCPPGE
PRKEAPANATTPQHKIQNGRGDETPGTLQKKARPPTLAVSQVESVQQAANTPIANNLLQA
PSTTLTPTTPCPSPSPSNSSEVAPSKSKEGKKEKKKKNNKNKNKKEPDNNNGESMSSDSD
TEQGGRGLEVPCTPTMTPSGIHSPATMQKYRDMIATAKGAKLVARKAKQDGTPNSARRKA
MVNREKRFTFVLAVVIGVFVICWFPFFFSYSLQAVCPESCALPEPLFKFFFWIGYCNSCL
NPVIYTIFNKDFRRAFKKILCKNTKGTFF
>Takifugu rubripes_ADRA2B(ENSTRUP_36242)
PAPYSPEATAAFATAITLMVVFTIVGNIMVIIAVLTSRSLRGPQNLFLVSLAAADILVAT
LIIPFSLANELLGYWYFKSLWCEIYLALDVLFCTSSIVHLCAISLDRYLSISRVTYGRQR
TPKRIKAAIVVVWLISAIISFPPLLSLNKSEAEDQENQRGPQCQLNDERWYILYSTIGSF
FAPCLIMILVYIKIYQIAKQRSRRPPGEPRKDGASCATPNQPARHVQANGKSSTPTSVPA
PNAKEEGKKGKRRGKKKADNNNGDSSSTESDMEHSHGGGRGSCSIPGSPAGGGIHSPGSV
KRFRDMIATSKGAQLVPGRKSKPESNPGAARRKAMVNREKRFTFVLAVVIGVFVVCWFPF
FFSYSLKAVCPDTCAIPDPLFTFFFWIGYCNSSLNPVIYTVFNKDFRKAFKKILCGSTKG
RKKSGFRL
>Homo sapiens_ADRA2C(ENSP_386069)
MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGF
LIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFG
QVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISA
VISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLR
TRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGA
LRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRR
RRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFK
FFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ
>Gallus gallus_ADRA2C(ENSGALP_25121)
MDLLLLGNTSLGSPNGSLALLPPSSPSSAALLQPPSPYSPAAVASLAALVGFIIVFTIVG
NVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMNYWYFGKVWCNIYL
ALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRIKAIIVTVWLISAVISFPPLI
SMYRDPEGDVFPQCKLNDETWYILSSCIVSFFAPCLIMVLVYIRIYRVAKLRTRTLSEKR
TMPEGSSQTENGLSRAAGGCTSLRMQLGENGHYSVHHWRKASELEDIELEESSTSESRRR
RSREEHPRKSSKSQSFSYSYSSKHSSSRLSRSSNRSMEFFSYRRRRKRSSICRKKVTQAR
EKRFTFVLAVVMGVFVVCWFPFFFSYSLYGICREACEVPETLFKFFFWIGYCNSSLNPVI
YTIFNQDFRRSFKHILFKKKKKNFRH
>Xenopus tropicalis_ADRA2C(ENSXETP_33692)
MEALENSTTTNSTPFPSSGVRGVWPYSMTSVWCLAAIVGFLIIFTIVGNVFVVIAVLTSR
ALKAPQNLFLVSLASADILVAALVMPFSLANELMGYWYFGNVWCDIYLALDVLFCTSSIV
HLCAISLDRYWSVTQAVEYNLKRTPRRIKGIIVTVWLISAVISFPPLISMDRDTEDDVYP
QCKLNDDTWYILSSCIGSFFAPCIIMILVYIRIYQVAKLRTRTLSEKKPTRDGSSHTENG
FSKGTTVKMPGDKENGHCPPRPSPPKATDVEDLELEESSMSESKRRKSSSKEDNTDSSKE
RKCSKGNSFSKQSSRLSRTSNKSMELFSSRKKKKRSSVSRRKLSQAREKRFTFVLAVVMG
VFVVCWFPFFFSYSLYGICREACEVPETLFKFFFWIGYCNSSLNPVIYTIFNQDFRRSFK
KIICIGRRKTFTH
>Danio rerio_ADRA2C(ENSDARP_101388)
MHNLSYASEEDTYTDTDFTPSGNSTNSTSYSPATIIGLAGLVSFLILFTIVGNVLVVIAV
LTSRALKPPQNLFLVSLASADILVATLIIPFSLANELMGYWFFGEVWCNIYLALDVLFCT
SSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKGMIVVVWLISAVISFPPLISMDRNTVD
ERRPMCQLNDHTWYILYSSIGSFFAPCVIMILVYIRIYQVAKTRTRNMSEKRRDPDGGSG
TPRLENGLSREDSRRENGHCSSSPGERKPAEDNPDADLEDSSSSDEKAKRSQNETAPSKK
DRRSSRKNSSSSKHSSRKSRASSKSLDLFSSRRKRRNTISRKKISQAREKRFTFVLAVVM
GVFVVCWFPFFFSYSLYGICREPCAIPDPLFKFFFWIGYCNSSLNPVIYTIFNQDFRRAF
QKILCKSWKRSF
>Takifugu rubripes_ADRA2Ca(ENSTRUP_8423)
QYTQLAIWGLAGLVGFLILFTIFGNVLVVIAVLTSRALKPPQNLFLVSLASADILVATLV
MPFSLANELMGYWFFGKIWCDIYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRT
PRRVKGMIVVVWLISAVISFPPLISMDRSSNETVPQCIINDETWYILYSSIGSFFAPCVI
MILVYIRIYQVAKTRTRTMSEKKRDVDSPQSTRDGSMKQQERENGHCQEQALGSPLPNEP
KHPATDHDDDFEDSSSSDEKPKKGSKHHHDDRKDRKSSRKSSSASKYSSRKSRASSKSME
LFASRRKRRSTVNRKKASAAREKRFTFVLAVVMGVFVVCWFPFFFSYSLYGICREPCQIP
VTLFKFFFWIGYCNSSLNPVIYTIFNQDFRRAFQKILWIAQERRDFKQ
>Takifugu rubripes_ADRA2Cb(ENSTRUP_27027)
AALVSFLILFTVVGNILVVVAVLTSRALKAPQNLFLVSLATADILVATLVMPFSLANELM
GYWYFGKVWCGIYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPKRVKGIIVL
VWLISAFISSPPLMSIDSNNDMSAQPQCEINDESWYILSSSIASFFAPCLIMVLVYIRIY
QVAKTRTRNMSEKDPRPDGATRAKVTSGSGREPARSNLQSPNSPRASPRKKVSQAREKRF
TFVLAVVMGVFVVCWFPFFFSYSLYGLCRDSCRIPDPLFKFFFWIGYCNSSLNPAIYTIF
NRDFRRAFQKILSISGCYK
>Tetraodon nigroviridis_ADRA2Ca(ENSTNIP_13049)
MEAFAVLQLNASWSLDGGYSLGATAGIAALVSFLILFTVVGNILVVVAVLTSRALRAPQN
LFLVSLATADILVATLVMPFSLANELMGYWYFGRVWCGIYLALDVLFCTSSIVHLCAISL
DRYWSVTQAVQYNLKRTPQRVKGTIVLVWLVSAFISSPPLLSMDSRQDGGARPQCELNDQ
SWYILSSSVASFFAPCLIMVLVYVRIYQVAKTRTRSLSQKEPGPEGAGVSAENGHCPPTP
SQRTITTAPQTEDGQLDGSSSSEGKGQTRERRGSEEKKSPGSKQSWRVCRASNKSAELLA
SRRKRRPSSAARKKMSQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGVCRDSCRIPDP
LFKFFFWIGYCNSSLNPAIYTIFNRDFRRAFQKILCQSWKKSF
>Tetraodon nigroviridis_ADRA2Cb(ENSTNIP_158)
MDFFNVSGVEERIEAGNISNATSQSQYTQLAIWGLAGLVGFLILFTIFGNVLVVIAVLTS
RALKPPQNLFLVSLASADILVATLVMPFSLANELMGYWFFGKIWCDIYLALDVLFCTSSI
VHLCAISLDRYWSVTQAVEYNLKRTPRRVKGMIVVVWLISAVISFPPLISMDRSSNETIP
QCIINDETWYILYSSIGSFFAPCVIMILVYIRIYQVAKTRTRTMSGKKREVDSPQENGMD
QAERGRGESLKSSREGSMKHQERENGHCQEQGVGSPLPNEPKHPAADHDDDFEDSSSSDE
KPKKASKRHHEDRKERKSSRKSSSASKYSSRKSRASSKSMELFSSRRKRRSTVNRKKASA
AREKRFTFVLAVVMGVFVVCWFPFFFSYSLYGICREPCKIPLTLFKFFFWIGYCNSSLNP
VIYTIFNQDFRRAFQKILCKSWKRSF
>Oryzias latipes_ADRA2Ca(ENSORLP_7613)
YSLAAVAGIAALVSFLILFTVVGNILVVIAVLTSRALKAPQNLFLVSLATADILVATLVM
PFSLANELMGYWYFGKVWCGIYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTP
RRIKCTILIVWLVSAFISSPPLVSIDRNNDISSQPQCELNDETWYILSSSIASFFAPCLI
MILVYIRIYQVAKTRTRSMSEKKPKPDGVTQTENGLSKVSSPLHGEAENGHCHCPPTPSQ
RTVTTGPQTQEVDVEESSSSEGKGHNPQRQDSQRARKARKSSFSKHSAHISRVSNKRKRR
RSSFARKKVSQAREKRFTFVLAVVMGVFVMCWFPFFFSYSLYGVCRDSCRIPDPLFKFFF
WIGYCNSSLNPAIYTIFNRDFRHAFQKILCKKTLSPYF
>Oryzias latipes_ADRA2Cb(ENSORLP_18075)
LNTSSLEEGLGDGNSSFNSTSESEYSQLTIWSLIGLVSFLILFTIVGNVLVVIAVLTSRA
LKPPQNLFLVSLATADILVATLVMPFSLSNELGYWFFGTVWCDIYLALDVLFCTSSIVHL
CAISLDRYWSVTQAVEYNLKRTPQRVKRMIVVVWLISAVISFPPLISMDRSSSKASQECK
LNDDTWYILYSSIGSFFAPCVIMILVYIRIYQVAKTRTRTISSSDEKTKKNRKLSKHQQE
DRKERKSSRKSSSASKCSSRKSRSSSKSMEFFSSRRKRRSTVHRKKVSAAREKRFTFVLA
VVMGVFVLCWFPFFFSYSLYSICRDPCKIPPTLFKFFFWIGYCNSSLNPVIYTIFNQDFR
RAFQKILCFVMCD
>Homo sapiens_HTR1A(ENSP_316244)
MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT
RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN
SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RQ
>Mus musculus_HTR1A(ENSMUSP_22235)
MDMFSLGQGNNTTTSLEPFGTGGNDTGLSNVTFSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSNPNECTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKKGAGT
SFGTSSAPPPKKSLNGQPGSGDCRRSAENRAVGTPCANGAVRQGEDDATLEVIEVHRVGN
SKGHLPLPSESGATSYVPACLERKNERTAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPELLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
R
>Gallus gallus_HTR1A(ENSGALP_23727)
MDVANNTTSPERSPEGEGGPGLAEVTLGYQLLTSLLLGTLILCAVSGNACVIAAIALERS
LQTVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVICDIFISLDVLCCTSSILH
LCAIALDRYWAITDPIDYVNKRTPRRAAVLISLTWLIGFLISIPPMLGWRTPEDRSNPDA
CTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFKAARFRIRKTVKKAEKKKIADTCLTLS
PAALQKKSNGEPGKGWRRTVEPRSGACVNGAVRQGEDGAALEVIEVQRCSSSSKTHLPLP
SEACGSPPPPSFERRNEKNTEAKRRMALSREKKTVKTLGIIMGTFILCWLPFFIVALVLP
FCDSKCYMPEWLGAVINWLGYSNSLLNPIIYAYFNKDFQSAFKKIIKCKFCRQ
>Danio rerio_HTR1Aa(ENSDARP_121666)
MESYNNTTESQDWSGNATSVSEVALSYQIIGSLFLAALILFAILGNACVIAAIALERSLQ
NVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQEMCDIFISLDVLCCTSSILHLC
AIALDRYWAITDPIDYVNKRTPRRAAILISLTWLIGFSISIPPMLGWRKPEDRADPDACT
ISQDHGYTIYSTFGAFYIPLILMLVLYGRIFRAARFRIRKTVKKTEKAKIADKCLAVSPA
LFPRKANGEVGKTWRRSVEPCANGALKNSDDGESFEITEVQSISKNHLSLPNNPQPCFEN
RNEKNTEAKRKVALARERKTVKTLGIIMGTFIFCWLPFFIVALVLPFCQDCFMPEWLGAV
INWLGYSNSLLNPVIYAYFNKDFQNAFKKILKCKCIRQ
>Danio rerio_HTR1Ab(ENSDARP_115108)
MEENNDTSFLFQNDSDLDHQTDNVTLPVKVPLSYQISTSLLIGALILCSIFGNACVVAAI
ALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLDKWTLGQVTCDIFISLDILCCT
SSILHLCAIALDRYWAITDPIDYMKKRTLKRAALLITVTWFVGFSISIPPMLIMKSQPKS
RAEDMANPEACMISHDPWYTIYSTFCAFYIPLILMLVLYGRIFKAARFRIRKTVRKPEKK
RVKCLTVSPALFKRANGELSKNWKSAVEPKPAACVNGAIKHAEDGESLEIIEVHSNSKNN
LPLPNTPNSVPLFENKHEKNTEAKRKLALARERKTVKTLGIIMGTFILCWLPFFIKALVM
PFCPTCVMPLWLQDVINWLGYSNSLLNPIIYAYFNKDFQSAFKKIIKCHFCRP
>Tetraodon nigroviridis_HTR1Aa(ENSTNIP_7803)
MDLRATSGNDSNATGGYSDATAVDWDEGENATGSGSLPDPELSYQIVTSLFLGTLILCSI
FGNSCVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQEICDI
FISLDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAALLISVTWLIGFSISIPP
MLGWRSAEDRANPDACIISQDPGYTIYSTFGAFYIPLILMLVLYGRIFKAARFRIRKTVK
KTETAKTSEMCLTLSPAVFHKRANGDAVSADWKRGYKFKPSSPCVNGAVRHGEEMESLEI
LEVSSNSKTHLPLPNTPQSSSHENINEKATGTKRKIALARERKTVKTLGIIMGTFIFCWL
PFFIVALVLPFCAENCYMPEWLGAVINWLGYSNSLLNPIIYAYFNKDFQSAFKKILRCKF
HRH
>Tetraodon nigroviridis_HTR1Ab(ENSTNIP_6646)
RKLVKMEGTNNTTDWTHPDNSSSRTSKPVDEAVKLGYQVVTSFLLGALILCSIFGNACVV
AAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNRWTLGQVPCDIFISLDML
CCTSSILHLCVIALDRYWAITEPIDYMKKRTPRRAAVLISVTWLVGFSISIPPMLIMRHQ
PRSMAEDRANSEQCKITQDPWYTIYSTFGAFYIPLTLMLVLYGRIFKAARFRIRRTVRKT
EKQKVSDSCLALSPAMFHRKTPRDAQGKSWKRSVEPQPLPNVNGAVKHAEEGESLEIIEV
QSNFKGSLPLPNAPSTVPLFENRQEKATETKRKIALARERKTVKTLGIIMGTFILCWLPF
FIVALIMPFCQETCYMPHWLRDVINWLGYSNSLLNPIIYAYFNKDFQSAFKKIINCHFCR
P
>Oryzias latipes_HTR1A(ENSORLP_5281)
MDFLTLSGNDSNTTSGYPEGRENGTGSGSQPGLMLSYQIITSLLLGALILCSIFGNACVV
AAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQEICDLFISLDVL
CCTSSILHLCAIALDRYWAITDPIDYVNKRTPMRAVLLICATWLIGFSISIPPMLGWRSA
EDRANPDACMISQDPGYTIYSTFGAFYIPLILMLVLYGRIFRAARFRIRKTVKKIETAKV
SDKCLAVSPAFFHKKSNGQSGGRGWKRCDGSKPSSPCVNGAVMHGDEGESLEIIEVISNS
KTHLPLPNTPQSSSHGYENMNERNSGAKRKLALSRERKTVKTLGIIMGTFIFCWLPFFIV
ALVLPFCPESCFMPDWLGAVINWLGYSNSLLNPIIYAYFNKDFQNAFKKIIKCKFHRP
>Homo sapiens_HTR1B(ENSP_358963)
MEEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSISLPWKVLLVMLLALIT
LATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQV
VCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISI
SLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIL
KQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSESGSPVYVNQVKVRVSDALLE
KKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYL
NSLINPIIYTMSNEDFKQAFHKLIRFKCTS
>Mus musculus_HTR1B(ENSMUSP_139389)
MEEQGIQCAPPPPAASQTGVPLTNLSHNCSADGYIYQDSIALPWKVLLVALLALITLATT
LSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDF
WLSSDITCCTASIMHLCVIALDRYWAITDAVEYSAKRTPKRAAIMIVLVWVFSISISLPP
FFWRQAKAEEEMLDCFVNTDHVLYTVYSTVGAFYLPTLLLIALYGRIYVEARSRILKQTP
NKTGKRLTRAQLITDSPGSTSSVTSINSRAPDVPSESGSPVYVNQVKVRVSDALLEKKKL
MAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFNWLGYLNSLI
NPIIYTMSNEDFKQAFHKLIRFKCAG
>Monodelphis domestica_HTR1B(ENSMODP_29968)
MEQPSRQCSPPASGSLTSSQTNHSTFPNPNCSSRDLEPYQDSIALPWKVLLATFLALITL
ATTLSNAFVIATVSRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVV
CDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAGMIVMVWVFSVSIS
MPPLFWRQAKAEEVADCSVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRILKQ
TPNRTGKRLTRAQLITDSPGSSSSGTSINSRVPEGPSESGSPVYVNQVKVKVSDALLEKK
KLMAARERKATRTLGIILGAFIVCWLPFFIISLALPICDNACWFHLAIFDFFNWLGYLNS
LINPIIYTKSNDDFKQAFQKLIRFRRTS
>Gallus gallus_HTR1B(ENSGALP_25570)
MEPASPCPAPLLPANDSYHGRNCSAEEGIYQDATPLSGKIVLAVVLALVTLATVLSNAFV
IATVYQTRKLHTPANYLIASLAFTDLLVSILVMPISTLYTVTGKWTLGQVVCDIWLSSDI
TCCTASILHLCVIALDRYWAITDAVEYSTKRTPKRAAGMIALVWVFSICISMPPLFWRQA
KAEEASNCAVNTDHVLYTVYSTVGAFYFPTLLLIALYGRIYVEARSRILKQTPKKAGKRL
TRAQLITDSPGSSSSVTSINSKAPEGPSETGSPVYMNQVKVKVSDALLEKKKLTAARERK
ATKTLGIILGAFIVCWLPFFIISLVLPICKDACWFHMAIFDFFTWLGYLNSLINPIIYTM
SNEDFKQAFHKLIRFRCTG
>Anolis carolinensis_HTR1B(ENSACAP_4679)
MEQSSPLCQADQANLEVFPHQPFNASSSPSSPNCSWQESPVYQDGTPLSWKVVLAALLAL
ITLATMLSNAFVIATVYQSRKLHSPANYLIASLAVTDLLVSILVMPISTMYTVTGKWTLG
QVVCDIWLSSDITCCTASILHLCVIALDRYWAITDAVEYSTKRTPKRAAIMIALVWVFSI
SISMPPFFWRQSKAEEMGDCMVNTDHILYTVYSTVGAFYLPTLLLIILYGRIYVEARSRI
LKQTPKKMGKRLTRAHLITDSPGSTSSVTSINCKASEASSETGSPVYMNQVKVKVSDALL
EKKKLTAARERKATKTLGIILGAFIVCWLPFFIITLVLPICKDACWFHMAISDFFTWLGY
LNSLINPIIYTMSNEDFKQAFHKLVRFRCTS
>Danio rerio_HTR1B(ENSDARP_70593)
MFSSGMERSGYFKPTPAHFEVLNSSTGTNVTLTPKTDEKQESFAFQVTLSSVLGLITLAT
ILSNAFVIATISQSRKLQTPANFLIASLAVTDLLVSVLVMPICVLYTVTREWTLGQVICD
IWLSSDITCCTASILHLCVIALDRYWAITDAVEYAKKRTQARAAGMVATAWIIAISISLP
PFFWRQVKAGELTTCSVNTDHIFYTIYSTFGAFYIPTLLLIALYGRIYVEARKRILKQSP
KKPGKRLTSAHLSTNSPASVASTSPLHCGRQDLCSDSGSLGSDNQIRVTVSDSLLEKKRI
SAARERKATKTLGIILGAYIVCWLPFFIYTLLIPLCSSCFSPELFDFFTWLGYVNSLINP
IIYTMSNDDFKKAFHKVISFRCCRR
>Takifugu rubripes_HTR1Ba(ENSTRUP_10981)
ISAESVAYQISLAVILSLITLATTLSNAFVIATISHSKKLQTPANFLIASLAVTDLLVSI
LVMPICVLYTVIHTWTLGQIVCDIWLSSDITCCTASILHLCVIALDRYWAITDAVEYSKK
RTPGRAAGMVAIAWVIAISISLPPLFWRQVKAEELTSCSVNTDHIFYTIYSTFGAFYIPT
LLLIVLYGRIYVEARKRILKQSPKRVGKRLTSAHLVTNSPGSVASTNSLQCGRHDTLSSD
TGSSASENQVKVTVSDALLEKKRISAARERKATKTLGIILGAYIVCWLPFFIYTLVVATC
ETCFIPELFDFFTWLGYLNSLINPIIYTMSNEDFKKAFHKLVRFNCRSRTNQII
>Takifugu rubripes_HTR1Bb(ENSTRUP_21542)
WTEATLLGLQISVSVVLAIVTLATMLSNAFVIATIFLTRKLHTPANFLIGSLAVTDMLVS
ILVMPISIVYTVSKTWSLGQIVCDIWLSSDITFCTASILHLCVIALDRYWAITDALEYSK
RRTMRRAAVMVAVVWVISISISMPPLFWRQAKAHEELKECMVNTDQISYTLYSTFGAFYV
PTVLLIILYGRIYVAARSRIFKTPSYSGKRFTTAQLIQTSAGSSLCSLNSASNQEAHLHS
GAGGEGGGSPLFVNSVKVKLADNVLERKRLCAARERKATKTLGIILGAFIICWLPFFVVT
LVWAICKECSFDPLLFDVFTWLGYLNSLINPVIYTVFNDEFKQAFQKLIKFSCAS
>Oryzias latipes_HTR1Ba(ENSORLP_18729)
ELLNISTNDTHANFTSKEEEKGTNLAFQAGLAVTLALITFATTLSNAFVIATIYQSRKLH
TPANFLIASLAVTDLLVSILVMPISALYTVCQTWTLGQVVCDIWLSSDITCCTASILHLC
VIALDRYWAITDAVEYSKKRTPARAAGMIATAWVIAISISLPPFFWRQVKAEEVTSCNVN
TDHIFYTIYSTFGAFYIPTLLLIALYGRIYVEARKRILKQSQNKPGKRLTSARLITNSPG
SVASTTSLNYGTNDTSSCDTTSSANVSQVKVTVSDALLEKKRISAAREKKATKTLGIILG
AYIICWLPFFIYTLLVPLCDSCFHPELFDIFTWLGYLNSLINPIIYTMSNEDFKQAFHKL
IRFRCCRA
>Oryzias latipes_HTR1Bb(ENSORLP_18282)
VEPTQSTNSTNDSLVLDSSTGEESAESLWYQISLAVILSLITLATTLSNAFVIATISQSK
KLQTPANFLIASLAITDLLVSILVMPICVLYTVIHTWTLGQIVCDIWLSSDITCCTASIL
HLCVIALDRYWAITDAVEYSKKRTPARAAGMVATAWVIAISISLPPLFWRQVKAEELTSC
SVNTDHIFYTIYSTFGAFYIPTLLLIVLYGRIYVEARKRILKQSPRKVGKRLTSAHLVTN
SPGSVASTTSLQCGRHDTPSSDTGSSTSDNQVKVTVSDALLEKKRISAARERKATKTLGI
ILGAYIVCWLPFFIYTLLVATCVACFNQELFDFFTWLGYLNSLINPIIYTMSNEDFKKAF
QKLLMFKDAKRLD
>Homo sapiens_HTR1D(ENSP_363748)
MSPLNQSAEGLPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVL
TTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDIT
CCTASILHLCVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLFWRQAK
AQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRILNPPSLYGKRFT
TAHLITGSAGSSLCSLNSSLHEGHSHSAGSPLFFNHVKIKLADSALERKRISAARERKAT
KILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFN
EEFRQAFQKIVPFRKAS
>Monodelphis domestica_HTRD1(ENSMODP_32418)
MPLQNQSAEDSPWSPPSKPLNSTEISEVWDAQTLQALKISLAVILAIITLATILSNTFVI
ITIFLTKKLHTPANYLIGSLAVTDLLVSILVMPISIAYTVTQTWTFGQIMCDIWLSSDIT
CCTASILHLCVIALDRYWAITDALEYSKRRTFGRAAAMIAMVWVISVCISIPPLFWRQAK
AHEELADCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYAAARTRILKPPSLYGKHFT
TAHLITGSAGTSLCSINSSLQEGQPHPGGSPLFIGPVKIKLASSLLERKRISAARERKAT
KTLGIILGAFIICWLPFFVVSLVLPICRDACWLHPAIFDFFTWLGYLNSLINPIIYTWFN
EEFKQAFQKLIRFRRGP
>Gallus gallus_HTR1D(ENSGALP_1192)
MTQYNLSAELSFQSSANKSLNFTEPPLAVDERTLLGLKISLSVLLSVITLATILANVFVV
ITIFLTRKLHTPANYLIGSLAVTDLLVSVLVMPISIAYTVTHTWAFGQVLCDIWLSSDIT
CCTASILHLCVIALDRYWAITDALEYAKRRTAGRAMLMIAVVWMISISISVPPFFWRQVK
AHEEIAKCNVNTDQISYTIYSTCGAFYIPTVLLLILYGRIYVAARSRILKPPSLYGKRFT
TAHLITGSAGSSLCSINASLHEGHSHSGGSPIFINHVQIKLADSILERKRISAARERKAT
KTLGIILGAFIFCWLPFFVMSLVLPICQDACWFHPILLDFFTWLGYLNSLINPVIYTAFN
EEFKQAFQKLIHFKKCSS
>Anolis carolinensis_HTR1D(ENSACAP_401)
MTQYNLSANLAFKDMSNKSLNGSRMPGDWDEDALGLKISLAVVLAAITLATMLFNVFVII
TIILTRKLHTPANYLIGSLAATDLLVSILVMPISIVYTVSHIWTFGQIMCDIWLSSDITC
CTASILHLCVIALDRYWAITDALEYSKRRTAGRAALMIAIVWVISICISMPPLFWRQAKA
HEILTDCKVNTDEISYTIYSTCGAFYIPTVLLLILYGRIYMAARSRILKPPSLYGKRFTT
AHLIAGSAGSSLCSLSSNLHEGHSHSSGSPMVINHVAIKVANNILERKRISAARERKATK
TLGIILGAFIFCWLPFFVMALALPICQDACSSPPALFDFFTWLGYLNSLINPVIYTAFNE
EFKQAFQKMIRFKKCS
>Danio rerio_HTR1D(ENSDARP_129450)
MDLFNSSDEFFLINATVSPTTLESWDDATLLSLQISISAMLAIVTLATALSNAFVIATIF
LTRKLHTPANFLIGSLAATDLLVSILVMPISIVYTVSKTWTLGQIVCDIWLSSDITFCTA
SILHLCVIALDRYWAITDALEYSKRRTMRRAALMIVIVWVISVSISLPPLFWRQAKAHEE
LTECMVNTDQISYTLYSTFGAFYVPTVLLMILYGRIYVAARSRIFKTPATSGKRFTAAQL
IQNSAGSSLCSLNSTSNQEGHLHAGGGGGSGGGGGGGGGSPLFTNSVKVKLADSVLERKR
LCAAREKKATKTLGIILGAFIVCWLPFFVFTLVMGVCKDCWYHPVLFDVFTWLGYLNSLI
NPVIYTAFNDDFKQAFHKLIKFKRCY
>Homo sapiens_HTR1E(ENSP_307766)
MNITNCTTEASMAIRPKTITEKMLICMTLVVITTLTTLLNLAVIMAIGTTKKLHQPANYL
ICSLAVTDLLVAVLVMPLSIIYIVMDRWKLGYFLCEVWLSVDMTCCTCSILHLCVIALDR
YWAITNAIEYARKRTAKRAALMILTVWTISIFISMPPLFWRSHRRLSPPPSQCTIQHDHV
IYTIYSTLGAFYIPLTLILILYYRIYHAAKSLYQKRGSSRHLSNRSTDSQNSFASCKLTQ
TFCVSDFSTSDPTTEFEKFHASIRIPPFDNDLDHPGERQQISSTRERKAARILGLILGAF
ILSWLPFFIKELIVGLSIYTVSSEVADFLTWLGYVNSLINPLLYTSFNEDFKLAFKKLIR
CREHT
>Macaca mulatta_HTR1E(ENSMUP_314)
MNITNCTTEAGMAVRPKTITEKMLICMTLVVITTLTTLLNLAVIMAICTTKKLHQPANYL
ICSLAVTDLLVAVLVMPLSIIYIVMDRWKLGYFLCEVWLSVDMTCCTCSILHLCVIALDR
YWAITNAIEYARKRTAKRAALMILTVWTISIFISMPPLFWRSHRRLSPPPSQCTIQHDHV
IYTIYSTLGAFYIPLTLILILYYRIYHAAKSLYQKRGSSRHLSNRSTDSQNSFANCKLTQ
TFCVSDFSTSDPTTEFEKFHASIRIPPFDNDLDHPGERQQISSTRERKAARILGLILGAF
ILSWLPFFIKELIVGLSIYTVSSEVADFLTWLGYVNSLINPLLYTSFNEDFKLAFKKLIR
CREHA
>Monodelphis domestica_HTR1E(ENSMODP_298)
MNFTNCTTEASVAIKSKSVTEKMLVSMTLVVITTMTTLLNSAVIIAICTTKKLHQPANYL
ICSLAVTDLLVAVLVMPLSITYIVMDSWTLGYFVCEVWLSVDMTCCTCSILHLCVIALDR
YWAITNAIEYARKRTAKRAGLMILTVWTISIFISMPPLFWRSHRLLSPPPSQCTIQHDHV
IYTIYSTLGAFYIPLTLILILYYRIYHAAKTLYQKRGSSRHLSNRSTDSQNSFASCKLTQ
TFCVSDFSTSDPTTEFDKINTSVRIPPFDNDLDQAGDRQQISSTRERKAARILGLILGAF
ILSWLPFFIKELIVGLSLYTVSSEVADFLTWLGYVNSLINPLLYTSFNEDFKLAFKRLVR
CREHS
>Gallus gallus_HTR1E(ENSGALP_25470)
MCILEGKMNFTNCTTEASAAAKPKTVTEKMLVTLTLATITTLTMLLNSAVIAAISTTKKL
HQPANYLICSLAVTDLLVAVLVMPLSITYIMIDKWTLGYFICEIWLSVDMTCCTCSILHL
CVIALDRYWAITDAIEYARKRTAKRAGLMIVTVWTISIFISMPPLFWRNHHSVSIPSECR
IQHDHVIYTIYSTFGAFYIPLTLILILYYRIYHAAKSLYQKRGSSRHLSNRSTDSQNSFA
SCKLTQTFCVSDFSTSDPTTEFDKINASVRIPPFENDLDLAGDRQQISTTRERKAARILG
LILGAFILSWLPFFIKELLVGLHLCIVSPEVADFLTWLGYVNSLINPLLYTSFNEDFKLA
FRKLIRCREHT
>Anolis carolinensis_HTR1E(ENSACAP_14947)
MNQTNLTTETNVTVQSKTATENMLIALTLSVITTLTMLLNSSVISAICTTKKLHQPANYL
ICSLAVTDLLVAVLVMPLSITYIVMERWTLGYFLCEIWLSIDMTCCTCSILHLCVIALDR
YWAITDAIEYARKRTAKRAAVMIGTVWTLSTFISMPPLFWRNHSVNIDSSECQIQHNHVI
YTIYSTFGAFYIPLTLILIVYYRIYHAAKSLYQKRGSSRHLSSRSTDSQNSFTSCKITQT
FCVSDFSTSDPTTEFDRMHASMKSPTFDNDLDLVGDRQQISSVRERKAARILGLILSAFI
LSWLPFFIKELIVGLGLGTVSTEVAHLLTWLGYVNSLINPLLYTSFNEDFKLAFKKLIKC
WEHS
>Danio rerio_HTR1E(ENSDARP_19694)
FWSSGMEMERYLGESTSSPANATNTSSEAASQVEALTERLAIVALLSLLTLLTAVVNGAV
IAAICTTRKLHLPANYLICSLAVTDFLVSVLVMPISILYITTEEWLLGTYVCEAWLSVDV
TCCTCSILHLCVIALDRYWAITKAIEYARKRTARRAGVMVAIVWVISIFISIPPLFWRQR
GDANGPQQCIIEHDHVGYTIFSTFGAFYIPMTLILILYSRIYSAAKTLYQKRGSSRHLSS
RSTDSQTSFNHCRVKHAFCVSDVSTSDHTMEFERNNVTIVRMPTFDTETPELDERNQICT
SRERKAARILGLILGAFILCWLPFFLKELLVGLKVLMTPSPQVSDALTWLGYINSLVNPL
LYTSFNEDFKQAFKRLIRRKEHT
>Homo sapiens_HTR1F(ENSP_322924)
MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANY
LICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALD
RYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHIV
STIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKS
VSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILG
AFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQK
LVRCRC
>Mus musculus_HTR1F(ENSMUSP_63136)
MDFLNASDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANY
LICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVLCDIWLSVDIICCTCSILHLSAIALD
RYRAITDAVEYARKRTPRHAGIMITIVWVISVFISMPPLFWRHQGTSRDDECVIKHDHIV
STIYSTFGAFYIPLVLILILYYKIYRAARTLYHKRQASRMIKEELNGQVFLESGEKSIKL
VSTSYMLEKSLSDPSTDFDRIHSTVKSPRSELKHEKSWRRQKISGTRERKAATTLGLILG
AFVICWLPFFVKELVVNVCEKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQK
LVRCRY
>Gallus gallus_HTR1F(ENSGALP_36052)
MDLINSTEQNSTSEELFKWVTSKILISITLSVLALMTTAINSLVMTAIIVTRKLHHPANY
LICSLAVTDFLVAVLVMPFSIVYIVKETWIMGQVVCDIWLSVDITCCTCSILHLSAIALD
RYRAITDAVEYARKRTPKHAGIMIAVVWIISIFISMPPLFWRHQTTSRDDECIIKHDHIV
STIYSTFGAFYIPLALILILYYKIYKAAKTFHRRSVSRIVREEVNGQVLLDAGERTTKLT
SMPSTIEKTSDPLVDCDKINISIRSPRSESKHEKSWKKQRISSTRERKAATTLGLILGAF
VICWLPFFVKEVVVNTCERCHISEDMSNFLAWLGYINSLINPLIYTIFNEDFKKAFQKLV
RCRQYL
>Anolis carolinensis_HTR1F(ENSACAP_13452)
MDFLNFTEQNYTLEQNGTSEELLKKVTPKILVSLTLSVLAVMTTVINSMVMTAIIVTRKL
HHPANYLICSLAVTDFLVAILVMPFSIVYIVKETWIMGQVMCDIWLSVDMTCCTCSILHL
SAIALDRYRAITDAVEYARKRTPKHAGIMIAIVWIISIFISIPPLYWRHQAANRDDECII
KHDHIASTIYSTFGAFYIPLALILILYYKIYKAAKTFHRRSVSRVLKEEANGQGLLEGGE
KSYRLTSSASCAKDKKSNPSGDLDRIHFSLRSPDSESKNEQGWRRQRISTTRERKAATTL
GLILGAFVICWLPFFVKEVVVNICERCQISEEMSNFLTWLGYINSLVNPLIYTIFNEDFK
KAFQKLIQCKSYL
>Takifugu rubripes_HTR1F(ENSTRUP_7299)
YVNSSSANGSGNDTLGTPKLPPRKILLTVTLFIVAVLTTFLNCLVITAIAVTRKLHHPAN
YLICSLAVTDLLVAVLVMPFSIVYIQKETWVMGQVMCTIWLSVDVTCCTCSILHLAAIAI
DRYRAITDAVEYSRKRTGAMAGQMVAVVWLLSILISLPPLLWRHFTEDSEQEDQCIIIHH
HIAFTLYSTFGAFYIPLLLILILYYKIYRAAQTLYMRREASRASRHSCMTNGSMIPSTYP
AGDGDLDGGPRSPEPLSPAEKSSDPSTEEPPRERMRAPKKSLQGSESRRSQFNQGPRISG
SRERKAAYTLGLIIGAFIICWLPFFVKEVIVNTCNSCYTSVEMADFLTWLGYINSLINPL
IYTIFNEDFKKAFQRLVRCSH
>Tetraodon nigroviridis_HTR1F(ENSTNIP_19519)
KILLTVTLFIVAILTTFLNCLVITAIAVTRKLHHPANYLICSLAVTDLLVAVLVMPFSIM
YIQKETWVMGQVMCTIWLSVDVTCCTCSILHLAAIAIDRYRAITDAVEYSRKRTGARAGQ
MVAVVWLLSILISLPPLLWRHFTEDSEQEDQCIIIHHHIAFTLYSTFGAFYIPLLLILIL
YYKIYRAAQTLYMRREASRASRHSCMTNGSMIPSSYPAGDGGPRSPEPLSPAEKSSDPST
EEPPRERVRAPKKSFQGPRISGSRERKAAYTLGLIIGAFIICWLPFFVKEVIVNTCDSCY
TSVEMADFLTWLGYINSLINPLIYTIFNEDFKKAFQRLCLFICSG
>Oryzias latipes_HTR1F(ENSORLP_19866)
MAGLMDFPNWTEWVYATNSSYNTLDSTKLPPSKILLSVTLSAVAILTTFFNCLVITAIAV
TRKLHHPANYLICSLAVTDLLVAVLVMPFSIIYIQKERWVMGEVVCTIWLSVDITCCTCS
ILHLAAIAIDRYRAITDAVEYSRKRTGARAGAMVAIVWFLSILISLPPLLWRHYSNDAEH
EDQCIIIHHHMAFTLYSTLGAFYIPLLLILILYYKIYKAAQTLYMRREASRASRHSCMTN
GSMIPSSYPTGDGDVDGGPRSPEPISPQERSFSELSTEEHPREKVRISKKDLKSKSRRHE
SHSESRRSQFYQGPRISGSRERKAASTLGLIIGAFVICWLPFFVKEVIVNTCSSCNTSME
MADFLTWLGYVNSLINPLIYTIFNEDFKKAFQRLVRCSCFCRN
>Homo sapiens_HTR5A(ENSP_287907)
MDLPVNLTSFSLSTPSPLETNHSLGKDDLRPSSPLLSVFGVLILTLLGFLVAATFAWNLL
VLATILRVRTFHRVPHNLVASMAVSDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIAC
DVLCCTASIWNVTAIALDRYWSITRHMEYTLRTRKCVSNVMIALTWALSAVISLAPLLFG
WGETYSEGSEECQVSREPSYAVFSTVGAFYLPLCVVLFVYWKIYKAAKFRVGSRKTNSVS
PISEAVEVKDSAKQPQMVFTVRHATVTFQPEGDTWREQKEQRAALMVGILIGVFVLCWIP
FFLTELISPLCSCDIPAIWKSIFLWLGYSNSFFNPLIYTAFNKNYNSAFKNFFSRQH
>Gorilla gorilla_HTR5A(ENSGGOP_15142)
MDLPVNLTSFSLSTPSPLETNHSLGKDDLRPSSPLLSVFGVLILTLLGFLVAATFAWNLL
VLATILRVRTFHRVPHNLVASMAISDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIAC
DVLCCTASIWNVTAIALDRYWSITRHMEYTLRTRKCVSNVMIALTWALSAVISLAPLLFG
WGETYSEGSEECQVSREPSYAVFSTVGAFYLPLCVVLFVYWKIYKAAKFRVGSRKTNSVS
PISEAVEVKDSAKQPQMVFTVRHATVTFQTEGDTWREQKEQRAALMVGILIGVFALCWIP
FFLTELISPLCSCDIPAIWKSIFLWLGYSNSFFNPLIYTAFNKNYNSAFKNFFSRQH
>Macaca mulatta_HTR5A(ENSMMUP_17184)
MDLPVNLTSFSLSTPSPLETNRSLGKDDLRPSSPLLSVFGVLILTLLGFLVAATFAWNLL
VLATILRVRTFHRVPHNLVASMAISDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIAC
DVLCCTASIWNVTAIALDRYWSITRHLEYTLRTRKCISNVMIALTWALSAVISLAPLLFG
WGETYSEGSEECQVSREPSYAVFSTVGAFYLPLCVVLFVYWKIYKAAKFRVGSRKTNSVS
PISEAVEVKDSAQQPQMVFTVRHATVTFQTEGDTWREQKEQRAALMVGILIGVFALCWIP
FFLTELISPLCSCDIPAIWKSIFLWLGYSNSFFNPLIYTAFNKNYNSAFKNFFSRQH
>Mus musculus_HTR5A(ENSMUSP_38884)
MDLPVNLTSFSLSTPSSLEPNRSLDTEVLRPSRPFLSAFRVLVLTLLGFLAAATFTWNLL
VLATILKVRTFHRVPHNLVASMAISDVLVAVLVMPLSLVHELSGRRWQLGRRLCQLWIAC
DVLCCTASIWNVTAIALDRYWSITRHLEYTLRTRKRVSNVMILLTWALSTVISLAPLLFG
WGETYSEPSEECQVSREPSYTVFSTVGAFYLPLCVVLFVYWKIYRAAKFRMGSRKTNSVS
PVPEAVEVKNATQHPQMVFTVRHATVTFQTEGDTWREQKEQRAALMVGILIGVFVLCWFP
FFVTELISPLCSWDVPAIWKSIFLWLGYSNSFFNPLIYTAFNRSYSSAFKVFFSKQQ
>Canis familiaris_HTR5A(ENSCAFP_7567)
MDSPVNLTYFSLFTPAPSETNHSSLGTGSEDPRPSPPLLSVFGVLVLTLLGCLVAATFSW
NLLVLATILRVRTFHRVPHNLVASMAISDVLVAALVMPLSLVHELSGRRWQLGRRLCQLW
IACDVLCCTASIWNVTAIALDRYWSITRHLEYTLRARRRVSNVMILLTWALSAVISLAPL
LFGWGETYSEGSEECQVSREPSYTVFSTVGAFYLPLCVVLFVYWKIYKAAKVRVGSRKTN
SVSPLTEAVEAKTSTQQPQMVFTVRHTTVTFQTEGDTWREQKDQKAALMVGILIGVFALC
WIPFFTTELISPLCSCDIPAIWKSIFLWLGYSNSFFNPLIYTAFNKNYNSAFKNFFSRQH
>Equus caballus_HTR5A(ENSECAP_16743)
MDLPGNLTYPSLSAPAPLETNRSLEAEDPRPSPPLLSVFGVLVLTLMGFLVAATFAWNLL
VLATILRVRTFHRVPHNLVASMAISDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIAC
DVLCCTASIWNVTAIALDRYWSITRHLEYTLRTRKRVSNVMIALTWALSAVISLTPLLFG
WGETYSEGSEECQVSREPSYTVFSTVGAFYLPFCVVLFVYWKIYKAAKFRVGSRKTNSVS
PLSEAVEVKASDQQPEMVFTVRHATVTFQTEGDSWREQKEQKAALMVGILIGVFVLCWIP
FFTTELISPLFSCDIPAIWKSIFLWLGYSNSFFNPLIYTAFNKNYNSAFKNFFSRQH
>Gallus gallus_HTR5A(ENSGALP_10269)
MDRQLNISCLGGATPDASNRSGSSRGLEGGRAQLSVFSVLVLTLLAMLVVATFLWNGLVL
ATIFRVRTFHRVPHNLVASMAISDVMVAALVMPLSLVHELSGRRWWLGRSLCQVWISFDV
LCCTASIWNVTAIALDRYWSITRHLEYTLRTRRRISNIMIALTWVLSAFISLAPLLFGWG
ETYSEDSEECQVSQEPSYTIFSTFGAFYLPLCVVLFVYWKIYKAAKFRIGSRKSNSITPV
SPEAPEIKEAAQQPQMVFTVRHATVTFQTDGDTWREQKERRAALMVGILIGVFVLCWIPF
FITELISPLCSCDIPPIWKSIFLWLGYSNSFFNPLIYTAFNKNYNNAFRNLFFRQH
>Anolis carolinensis_HTR5A(ENSACAP_10761)
MMDWSPNFTCFSVTALANSNQTGSDSAEDLPSKDRSLSVFTVLILTLLAMLAVATFLWNL
LVLATILRVRTFHRVPHNLVASMAISDVMVAALVMPLSLVHELSGHRWRLGRALCQAWIS
CDVLCCTASIWNVTAIALDRYWSITRHLEYTLRTRRRISNIMIALTWFLSAIISLAPVLF
GWGETYSEGNEECQVSREPSYTIFSTFGAFYVPLCVVLFVYWKIYKAAKFRIGSRKSNSI
TPISPEALEVKEASQQPQMVFTVRHATVTFQTDGDTWREQKEKKAALMVGILIGVFVLCW
IPFFITELLNPLCSCDIPPLWKSIFLWLGYSNSFFNPLIYTAFNKNYNNAFKSLFSRQP
>Danio rerio_HTR5A(ENSDARP_89964)
MTQPNVTALSANISGGSESGNLYRPFSVFSVLTLTLLAMLVVATFVWNLLVLVTILRVRT
FHRVPHNLVASMAISDVMVAGLVMPLSLVRELYGRRWILGRALCQVWISCDVLCCTASIW
NVTAIALDRYWSITRHLEYTLKTRKRISNVMIGLTWLLSSVISLSPLFGWGETYSEDSLA
CQVSQEPSYTVFSTFGAFYLPLCVVLFVYWKIYKAAKFRIGSRKTNTITPMAEVIEVKEA
ERQPQMAFTVRHATVSFQTDGETWREQKERRAALMVGILIGVFVLCWIPFFLAELIIPLC
SCDIPPVWKSVFLWLGYSNSFFNPLIYTAFNKNYNNAFRNLFSRQR
>Takifugu rubripes_HTR5A(ENSTRUP_45813)
MAYPNTSVLTANVSSTTDAFDSGGNIYRPFSVFSVLTLTLLAMLVVATFVWNLLVLVTIL
RVRTFHRVPHNLVASMAISDVMVAALVMPLSLVHELNGRLWKLGRVLCQVWISFDVLCCT
ASIWNVTAIALDRYWSITRHLQYTLKTRKKISNVMIALTWLLSSIISLSPLFGWGRTYSE
GMKCQMSQEPSYTIFSTFGAFYLPLCVVLFVYWKIYKAAKFRIGSRKTNTITPMAEGVKV
KEETRPQMVFTVRHATVTFQTDGDTWREQKEKKAALMVGILIGVFVLCWIPFFITELIVP
LCSCDIPPIWKSIFLWLGYSNSFFNPLIYTAFNKNYNNALRNLFSRQR
>Tetraodon nigroviridis_HTR5A(ENSTNIP_15748)
RPFSIFSVLALTLLAMLVVATFVWNLLVLVTILRVRTFHRVPHNLVASMAISDVMVAALV
MPLSLVHELNGRLWKLGRVLCQVWISFDVLCCTASIWNVTAIALDRYWSITRHLQYTLKT
RKKISNVMIALTWLLSSIISLSPLFGWGGTYSEGMKCQMSQEPSYTIFSTFGAFYLPLCV
VLFVYWKIYKAAKFRIGSRKTNTITPMAECAVQVKEETRPQMVFTVRHATVTFQTDGDTW
REQKEKKAALMVGILIGVFVLCWIPFFITELIVPLCSCDIPPIWKSIFLWLGYSNSFFNP
LIYTAFNKNYNNALRNLFSRQR
>Homo sapiens_HTR7(ENSP_337949)
MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTW
DAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLI
VSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDR
YLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYT
IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVE
ECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC
IPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALK
LAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
>Mus musculus_HTR7(ENSMUSP_126847)
MMDVNSSGRPDLYGHLRSLILPEVGRRLQDLSPDGGAHSVVSSWMPHLLSGFPEVTASPA
PTWDAPPDNVSGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSN
YLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVIS
IDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDF
GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFSGFPRVQPESVISLNGVVKLQK
EVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTS
CSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHE
ALKLAERPERSEFVLQNCDHCGKKGHDT
>Monodelphis domestica_HTR7(ENSMODP_8519)
MVMDINSSGGGVSDPSYYSSLRSFLLQEVGQGLRDLSPDGGGGGSDGMISGSWEPNLLQV
IQEVTASPEPGASSDNDTVCGEQINYGNTEKVVIGAILSLITLLTIAGNCLVVISVCFVK
KLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASI
MTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKV
CLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAAKRSAAKHKFTGFPRVEENNEGVIS
VNGMVKLHKDPEECANFSRLLKQERKNISIFKREQKAATTLGIIVGAFTVCWLPFFILST
ARPFICGTSCSCIPLWMERTFLWLGYANSLINPFIYAFFNRDLRTTYRNLLQCRYRNINR
KLSAAGMHEALKLAERPEFVLQNSDYCRKKSHDS
>Pelodiscus sinensis_HTR7(ENSPSIP_174)
MVAGSQSPRLLRIIQDVTSSPSPASSLTADNDTGCGEQILSYGNMEKVVIGAILSLITLL
TIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGEWIFGHVF
CNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILCVWLLSASIT
IPPLFGWAQNVNDEKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAAKKSAAKHK
FTGFPRPEENEGMVSVNGVIKLHKESEECTNFSRLLKHDRKNISIFKREQKAATTLGIIV
GAFTVCWLPFFILSTARPFICGTACSCIPFWVERTFLWLGYANSLINPFIYAFFNRDLRT
TYRNLLQCRYRNINRKLSAAGMHEALKLAEKPEFVLKHCSRDILLSGKAQEKSISRPCS
>Xenopus tropicalis_HTR7(ENSXETP_60854)
MVIVINSSYMHSNIRSYVIEELKDHSTSIMISGSFDPRLPKILQDATTASPISTSTFSSE
NDTQCGELMILNYGHIEKLVIGAILSLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSL
ALADLSVAIAVMPFVSVTDLIGGEWIFGHVFCNVFIAMDVMCCTASIMTLCVISIDRYLG
ITRPLTYPVRQNGRCMAKMILCVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYS
TAVAFYIPMSVMLFMYYRIFKAAKRSAAKHKFTGLPRPEESEGMISANGNVKTHKESEEC
TNLSKLLRNDRKNISIFKREQKAATTLGIIVGAFTICWLPFFLLSTARPFICGTECSCIP
LWLERTFLWLGYANSLINPFIYAFFNRDLRTTYRNLLQCRYRNINRKLSAAGMHEALKLA
ERPDRAFYLLFKLKQFPKRSVST
>Danio rerio_HTR7(ENSDARP_104607)
XPRSNGSCGEQRTLDPDLTKTVIVGLMLSSITAVTVMGNTLVVIAVCVVKKLRQPSNYLL
VSLAIADLSVAVAVMPFAIVTDLTGGVWLFGEVFCNIFIGMDVMCCTASIMTLCVISVDR
YLGITRPLTYPARQNGQLMAKMIVGVWLVSASITLPPFCGWAHNVNTAGVCLISQDVGYT
LYSTAVAFYIPMVVMLFMYYKIFKAARRSGAKHNFTSLPPIQLACPEPALATVDGFCMHG
MKNGATSEEFSALSCLLNRERRSASIFRREQKAATTLGVIMGVFSFCWLPFFLFTTARPF
ICGLLCNCAPVWLERVLLWLGYTNSLMNPFIYAFFNRDLRSTYKDLLRCRYRNINRRLSA
MGVHEALKL
>Takifugu rubripes_HTR7(ENSTRUP_19044)
MVAVGASNGSFTGGNIRSSFMIEDRVGGEDPGGSTNMMISEALAPRLLMIAQGAAEAAAA
AATTSPSTSSQHQVMEPNGTRCGEEIFSYGRVEKVLIGGVLTMLTLSTICGNLLVVISVC
FVKKLRQPSNYLIVSLAMADLSVALAVMPFVSITDLIGGQWIFGQFFCNVFIAMDVMCCT
ASIMSLCVISIDRYLGITNPLTYPVRQNGCCMAKMILSVWLLSASITLPPLFGWAQNVND
GRVCLISQDFGYTVYSTAVAFYIPMSVMLIMYYRIYRAAKLSAAKHTITGFPRQGHESLD
CVAAALKLQREVEEECSTRVSRLLKTGEYHQRRKRKNQSIFKREQKAAATLGIVVGAFTF
CWLPFFLVSTARPFICGVECSCVPLWLERTLLWLGYANSLINPFIYAFFNRDLRTTYSNL
LRCRYRNINRKLSAAGMHEALKLVEKPD
>Tetraodon nigroviridis_HTR7a(ENSTNIP_16385)
NGTRCGEEILGYGRAEKVLIGGVLTMLTLSTICGNLLVVISVCFVKKLRQPSNYLIVSLA
VADLSVALAVMPFVSITDLIGGQWVFGQFFCNVFIAMDVMCCTASIMTLCVISIDRYLGI
TNPLTYPVRQNGCCMAKMILSVWLLSASITLPPLFGWAQNVNDGRVCLISQDFGYTVYST
AVAFYIPMSVMLIMYYRIYRAAKLSAAKHTITGFPRQVEEESLDCVAAALKLQREVEEEC
STRVSRLLKTGEYHQRRQRKNQSIFKREQKAAATLGIVVGAFTFCWLPFFLVSTARPFVC
GVECSCVPLWLERTLLWLGYANSLINPFIYAFFNRDLRTTYSNLLRCRYRNINRKLSAAG
MHEALKLVEKPDADMAEFVL
>Tetraodon nigroviridis_HTR7b(ENSTNIP_19860)
VTISPTAMWNESCGEQPLDFGRPQKIFIGVMLAIITAVTVMGNTLVVIAVSVVKKLRQPS
NYLLVSLAVADLSVAIVVMPFVIVTDLTGGKWLFGEVFCNIFIGMDVMCCTASIMTLCVI
SVDRYLGITRPLTYPARQNGQLMAKMILGVWLVSASITLPPFCGWAKNVHKDGVCLISQD
FGYTIYSTAVAFYIPMLVMLVMYYKIFRAARKSGAKHRFIDFSRRERLETEANEALRMQG
LKPAGVAEECAALSRLLNRERRNISIFKREQKAATTLGVIVGVFGFCWLPFFILTTARPF
ICGVECSCVPFWLERTLLWLGYANSLMNPFIYAFFNRDLRSTYRDLLRCRYRNINRRLSA
VGVHEALKV
>Oryzias latipes_HTR7a(ENSORLP_18673)
CGEQLLDFGRPEKIIIGVMLAIITAVTVMGNTLVVIAVCVVKKLRQPSNYLLVSLAVADL
SVAIVVMPFVIVTDLTGGKWLFGEVFCNIFIGMDVMCCTASIMTLCVISVDRYLGITRPL
TYPARQNGQLMAKMILGVWLVSASITLPPFCGWAKNVHKAGVCLISQDFGYTIYSTAVAF
YIPMLVMLVMYYKIFRAARKSGAKHRFTDLLRRERLETVANEALRMQGLKPSGVAEECAT
LSRLLNRERKNISIFKREQKAATTLGVIVGVFAVCWLPFFILSTARPFICGVECSCVPIW
LERTLLWLGYANSLMNPFIYAFFNRDLRSTYRDLLRCRYRNINRRLSAVGVHEALKATSI
PQENATITSPALDLQCDNAGTKGHYT
>Oryzias latipes_HTR7b(ENSORLP_4476)
AAAAAAATSPSTSSQPQVMETNGTRCGEQILSYGRVEKVLIGGVLTMLTLSTICGNMLVV
ISVCFVKKLRQPSNYLIVSLAVADLSVALAVMPFVSITDLIGGQWVFGQFFCNVFIAMDV
MCCTASIMSLCVISIDRYLGITKPLTYPVRQNGCCMAKMVLSVWLLSASITLPPLFGWAQ
NVNDGRVCLISQDFGYTVYSTAVAFYIPMSVMLIMYYRIFRAAKLSAAKHTITGFPRLGD
SQAAATHREGRGGHKALQLSESGETGSVEGTEAEPEGELEEEESLDCVAAALKLQREVEE
ECSTRVSRLLKSGEHHQRRKRKNQSIFKREQKAAATLGIVVGAFTFCWLPFFLVSTARPF
ICGVECSCVPLWLERTLLWLGYANSLINPFIYAFFNRDLRTTYSNLLRCRYRN
>Ciona intestinalis_(ENSCINP_24469)
LTNFTTQGLPNVSELFPNIENETNGSNIAYKVGLSILLGSICTVTVLGNLIVIFTAILFR
QLRTIPNMFIISLASADLLMGTIVLPMWSHYVIGDFKWSLGFFWCDVWTSIDVLSVTASI
GTLCAISLDRFVAITMPFKYATKMTRPRARFIIGFIWMVSGTIAFVPINLGWWKTNKPED
LECYDSPTCCEFRPNVIYAVVSSCISFYIPLIIMICAYSVVFKSKAMFAFWRPDYLSVKI
FISTTVAIQKRGVLPWEKREHRAVITMGIIMGTFVVCWLPFFIVNIAQSVTKITRFRYPF
LMVNCLGYTNSLFNPIIYCRSEEFRKAFKRVL
>Ciona intestinalis_(ENSCINP_9209)
LITLALTSLLSLLIVVGNGLIIVSVALVKKLRQPANYLIVSLALSDFLVGLVVLPLTIVY
DIMGEWVFGPNVCDVHVSFDVICCTASIMNLCMISIDRYLMITQPMTYPKRRTGKLMLLL
IATAWVLSCLVIIPALFGFTKKRQRFAINQTAGYENPMLGEFQVFGIKKYGKACLISQER
WFTIYSTLGAFYLPLAVMLCMYWKIYLEASRFNARHRLRSYSTTGSQRQTGERLGMKNGF
PRNGTTRHNGMEWRFPTISEVDILTSLNEEGEQTNKETETETINGKINEEYRARTLYTRA
SANSLLATEKTPKLVGKPSPRSRLFMLYGKPRLLRATSTPCPTTTNKPNTQHTRKSSFRT
LRQNSEITFPCNRRPTVFNQIRRRVSLATSRDRMRNVKATRTLGIVVGAFTFCWLPFFIV
TFLRPFACPIPESQDCIPLWLVRFVLWLGYLNSALNPLIYIGFSPDLRETFRFLICCKCT
NVDRRLAQIELRQAIAVERKASMASRSYAPESIV
>Ciona savignyi_(ENSCSAVP_15309)
TVYSDGEVILLSILTMLLCSLGLFGNLTVILVIWKDRVISKHRQNLYLLSLAVADASLVV
LVVPFSLTNELLGHWPFGAVYCRIYLSVDILLCTASIWNICVIGLDRYISVKYPMTYRKF
RTMPKIRLFIISVWLFAAGVSLLPFVSEIETINSERGCFINASSWYIVASCLLSFFVPSF
IIWPVYIKIYMIGRDLEISKRARHTPAPSHTKPEWKERRGRSFETTAFRRGSGKTGSSED
FMKLLDVPNNTNTGSRSLSTDQQMMVRSQSFIASSGHEEGANLLFSSPTLKPKDPVSLPN
PKFIKTSDQTQHPTAPLSSSQSQRSSCANAMSRRERRFVCIISIITGCFMACWMPFFLTY
SIYAICRNCCLNNTLFKVFFWLGYLNSALNPVLYTAFNKDFRSAFKRLFRADSNRTS
>Ciona savignyi_(ENSCSAVP_5042)
AALTSLLSLLIVVGNGLIIVSVALVKKLRQPANYLIVSLALSDFLVGLVVLPLTIVYDIM
GEWVFGPNVCDVHVSFDVICCTASIMNLCMISIDRYLMITQPMTYPKRRTGKLMLLLIAT
AWLLSCLVIIPALFGFTKNVKDGKTCLISQERWFTIYSTLGAFYLPLAVMLCMYWKIYLE
ASRFNSRHRLRSYSTSGSQVGNSHLISKHSVVFDDDTISSSGDEFVAADSVGKCGSEVEE
SLDGKRTLDGGYDRKTYSLPDRAHAHRNGGVNGGSKRANGVNGVELIRCESGIALEERNG
ASRHQRANGVEWRPTVFNQIRRRVSLATSRDRMRNVKATRTLGIVVGAFTFCWLPFFIVT
FLRPFACPIPEAQDCIPLWLVRFVLWLGYLNSALNPLIYIGFSPDLRETFRFLICCK
>Branchiostoma floridae_(XP_2608949)
MDGLPLDNFTFDDNGTFNVTEVEDQSQVLGLRMSLTASVLVGTVLSCICLLTIAGNILVVLAVCLERSLR
TNIGYFYINLAIADLLLGCLVLPFSAARELLNYWPFGEALCELWAAVDVLCCTASIFSLCSISLDRYIGV
TRPLHHNMIVTKRRVVVILVAVWAISAAISVGPLFGWKHPKSYQNSQCNINGSPSYIIFSVVGSFYVPAF
IVLYVYRQVYRAAVRETSKLMITLKAQEDRNPASAESVRIHRGKTVTAESRQSPPRLSPNSSKPRMVKEA
LGSVKNRIEKFTKEKKAAKTVGIIVGVFLVCWLPFFIMYPIDSMIVKVPELLITMAFWLGYCNSFLNPII
YACSNGHFRRAFRRVLLCGKRQSRFPTMRSEDYTLSSRSSCRRVHSNYSSQGSSKRQQLKIQLQELTVS
>Branchiostoma floridae_(XP_25950)
AVAGIVAMVGIIAGNCLVCVAIAKDRSLKAVQNWYLVSLAVCDLMVGALIMPFSLANEIMGYWYFGQVWC
EVYLMMDVLACTASIWNLCLISLDRLWSVTNPIKHSNKRKPKWVCGMITVAWLLSLVVCVPPLFGWKGDQ
LPDGTCDINASFEYSIYSSVGSFFIPLVLMTSMYTKIFMTETCRERNICREACTRPSGHIFLSRQSLHLP
PMPPERPVKEEKDQELGENDDSTSAGRSVNSTAVLGPAAQKDDSSLESTGGQDLDPAAAQALAFPGTKSR
IMHVRERRFTILLGVILGAFILCWLPFFLTLFLQAVCTTCRDNTPLLLFKFFFWIGYLNSAANPIIYTVF
NRDFRRAFKR
>Strongylocentrotus purpuratus_(XP_3724366)
MYQRILWSANKTMAGTTPASYFAEYDPLYSSASILSNYSANDNLSGPNVSPQPYPPSGYGLTRILICSFM
ALIVIILIVIGNIMVCIAVFKERSLQAVQNWFLVSLAASDLMVGILIMPLGVVNEMLGHWIFGNHVCLLW
LVLDVLACTASILNLCLISIDRYCSITRPIKHAEWRQPCRIRSMIFMVWLLSILISVPPLFGWRSEIKMG
DNGYYKCVISEDIGYILYSTMGSFYIPAFIMVIVYWKIWLAAKRRARSTVRKSKRTNGKNMIASECISVD
DRTNFDGKTYAMIHKADPDIQMATLQVDHEHIARPIPSACGTSSSNPDVDSTHDRIPHSPSENTLHPPSI
TTSTSLLPPGMRASDTHLRPDTPQMQHRPSRIDPHEIEKQKRRLAQSRDRRATIVLGVIMGTFLACWYPF
FQLYVISALCGPSCKIPRLLFDFFFWIGYCNSALNPIIYTIFNRDFRRAFKKMLGFRRRPKKR
>Drosophila melanogaster_(FBpp85761)
MAHETSFNDALDYIYIANSMNDRAFLIAEPHPEQPNVDGQDQDDAELEELDDMAVTDDGQ
LEDTNNNNNSKRYYSSGKRRADFIGSLALKPPPTDVNTTTTTAGSPLATAALAAAAASAS
VAAAAARITAKAAHRALTTKQDATSSPASSPALQLIDMDNNYTNVAVGLGAMLLNDTLLL
EGNDSSLFGEMLANRSGQLDLINGTGGLNVTTSKVAEDDFTQLLRMAVTSVLLGLMILVT
IIGNVFVIAAIILERNLQNVANYLVASLAVADLFVACLVMPLGAVYEISQGWILGPELCD
IWTSCDVLCCTASILHLVAIAVDRYWAVTNIDYIHSRTSNRVFMMIFCVWTAAVIVSLAP
QFGWKDPDYLQRIEQQKCMVSQDVSYQVFATCCTFYVPLLVILALYWKIYQTARKRIHRR
RPRPVDAAVNNNQPDGGAATDTKLHRLRLRLGRFSTAKSKTGSAVGVSGPASGGRALGLV
DGNSTNTVNTVEDTEFSSSNVDSKSRAGVEAPSTSGNQIATVSHLVALAKQQGKSTAKSS
AAVNGMAPSGRQEDDGQRPEHGEQEDREELEDQDEQVGPQPTTATSAMTAAGTNESEDQC
KANGVEVLEDPQLQQQLEQVQQLQKSVKSGGGGGASTSNATTITSISALSPQTPTSQGVG
IAAAAAGPMTAKTSTLTSCNQSHPLCGTANESPSTPEPRSRQPTTPQQQPHQQAHQQQQQ
QQQLSSIANPMQKVNKRKETLEAKRERKAAKTLAIITGAFVVCWLPFFVMALTMPLCAAC
QISDSVASLFLWLGYFNSTLNPVIYTIFSPEFRQAFKRILFGGHRPVHYRSGKL
>Apis mellifera_(NP_1011567)
MNESAVYLLGSEEEGNQLNRSFYSASYPPQNRSQEEDLWNLATDRAGLAILLFLFSVATVFGNTLVILAV
VRERYLHTATNYFVTSLAFADCLVGLVVMPFSAIYEVLENRWLFTTDWCDVWRSLDVLFSTASILNLCVI
SLDRYWAITDPFTYPSKMSRRRAAVLIAIVWICSSAISFPAIVWWRAVRTEEVPEDKCPFTEHLGYLIFS
STISFYLPLFVMVFTYYKIYRAAVIQTKSLKLGTKQVLMASGELELTLRIHRGGGTNTDARHLFRTASST
PEDLQDLEEPLTTIQHNNCLTRIPSTRINKQHTRGNNFSLSRKLAKFAKEKKAAKTLGIVMGVFIICWLP
FFVVNLWSGFCSQCIWQEKIVFAAVTWLGWINSGMNPVIYACWSRDFRRAFVRILCACCPGRVRRRYQPA
FRCKPSQRFASGRYYSAYSLHHVRSSRESSCEQTYI
>Apis mellifera_(ENSCINP_24469)
MEEHVNQTSRNSSSDGLVFTDASIILRTLVLGLLILVTVVGNLFVIAAILLERNLQSVANYLIVSLAVAD
LMVACLVMPLGAVYEINSEWSLGPELCDMWTSSDVLCCTASILHLVAIAVDRYWAVTDLNYIQARNPRRI
GMLIVAVWVVSLGISLAPQLGWKDPDYLDRIADGTCLVSQDPAYQIFATCATFYLPLLVILFLYWRIFQA
ARKRIRRRPGTIVQPARERRGILRYVTKRPREESTAFTITRSTPDHSSISPEKSSSYNGANATQSTTVTP
STVSTTTTTTTTTTVTNPSSSHSTHSSSKRTRDTIESKREKKAAKTLAIITGAFVACWLPFFVVALLRAT
CQACEPPELIASVFLWLGYFNSTLNPVIYTVFSPEFRQAFKRMLCGGSRIIR