>Homo sapiens_ADAM7(ENST_380789)
MLPGCIFLMILLIPQVKEKFILGVEGQQLVRPKKLPLIQKRDTGHTHDDDILKTYEEELL
YEIKLNRKTLVLHLLRSREFLGSNYSETFYSMKGEAFTRHPQIMDHCFYQGSIVHEYDSA
ASISTCNGLRGFFRINDQRYLIEPVKYSDEGEHLVFKYNLRVPYGANYSCTELNFTRKTV
PGDNESEEDSKIKGIHDEKYVELFIVADDTVYRRNGHPHNKLRNRIWGMVNFVNMIYKTL
NIHVTLVGIEIWTHEDKIELYSNIETTLLRFSFWQEKILKTRKDFDHVVLLSGKWLYSHV
QGISYPGGMCLPYYSTSIIKDLLPDTNIIANRMAHQLGHNLGMQHDEFPCTCPSGKCVMD
SDGSIPALKFSKCSQNQYHQYLKDYKPTCMLNIPFPYNFHDFQFCGNKKLDEGEECDCGP
AQECTNPCCDAHTCVLKPGFTCAEGECCESCQIKKAGSICRPAKDECDFPEMCTGHSPAC
PKDQFRVNGFPCKNSEGYCFMGKCPTREDQCSELFDDEAIESHDICYKMNTKGNKFGYCK
NKENRFLPCEEKDVRCGKIYCTGGELSSLLGEDKTYHLKDPQKNATVKCKTIFLYHDSTD
IGLVASGTKCGEGMVCNNGECLNMEKVYISTNCPSQCNENPVDGHGLQCHCEEGQAPVAC
EETLHVTNITILVVVLVLVIVGIGVLILLVRYRKCIKLKQVQSPPTETLGVENKGYFGDE
QQIRTEPILPEIHFLNQRTPESLESLPTSFSSPHYITLKPASKDSRGIADPNQSAK

>Pan troglodytes_ADAM7(ENSPTRP_53219)
MLPGCIFLMILLIPQVKEKFILGVEGQQLVRPKKLPLIQKRDTGHTHDDDIPKTYEEELL
YEIKLNRKTLVLHLLRSREFLGSNYSETFYSMKGEAFTRHPQIVDHCFYQGSIVHEYDSA
ASISTCNGLRGFFRINDQRYLIEPVKYSDEGEHLVFKYNLRMPYVANYSCTELNFTRKTV
PGDNESEEDSKIKGIHDEKYVELFIVADDTVYRRNSHPHNKLRNRIWGMVNFVNMIYKTL
NIHVTLVGIEIWTHEDKIELYSNIETTLLHFSFWQEKMLKTRKDFDHVVLLSGKWLYSHV
QGISYPGGMCLPYYSTSIIKDLLPDTNIIANRMAHQLGHNLGMQHDEFPCTCPSGKCVMD
SDGSIPALKFSKCSQNQYHQYLKDYKPTCMLNIPFPYNFHDFQFCGNKKLDEGEECDCGP
AQECTNPCCDAHTCVLKPGFTCAEGECCESCQIKKAGSICRPAKDECDFPEMCTGHSPAC
PKDQFRVNGFPCKNSEGYCFMGKCPTREDQCSELFDDEAIESHDICYKMNTKGNKFGYCK
NKENRFLPCEEKDVRCGKIYCTGGELSSLLGEDKTYHLKDPQQNATVKCKTIFLYHDSTD
IGLVASGTKCGEGMVCNNGECLNMEKVYISTNCPSQCRENPVDGHGLQCHCEEGQEPVAC
EETLNVTNITVLVVVLVLVIVGIGVLILLVRYRKCIKLKQVQSPPTETLGVENKGYFGDE
QQIRTEPILPEIHFRNQRTPESLESLATSFSSPHYITLKPASKDSRGIADPNQSAK

>Mus musculus_ADAM7(ENSMUSP_22640)
MLTTGIFWMTVLISHIQERGIVGVEGQELVHPKKLPLLHKRDLERIHDSDIPEEYEEELL
YEIKLGKKTLILHLLKAREFLSSNYSETYYNVKREVFTKHPQILDHCFYQGSIIHEFDSA
ASISTCNGLRGFFRVNDQRYLIEPVKYSDDGEHLVYKYNVKAPYATNHSCVGLNFTKKSA
LIDVENIEEHNAEDHHKEKFIELFVVADEYVYRRNNKPQNKLRKRIWGMVNFVNMIYKTL
NIHVTLAGFEIWSAGDKIEIVSNLESTLLHFSTWQETVLKKRKDFDHVILLSGKWLYTSM
QGIAYPGGICQILRSCSVVKDLLPDVNIIGNRMAHQLGHSLGMQHDGFPCTCPLGKCVMG
DGSIPAIKFSKCSQTQYQQFLQDQKPACILNNPFPEEFNDYPFCGNKKVDEGEECDCGPV
QECTNPCCDAHKCVLKPGFTCVEGECCESCQMKKEGAVCRLAKNECDISEVCTGYSPECP
KDEFQANGFPCRNGEGYCFMGLCPTRNEQCSELFIGGAEESHSLCYRMNKKGNRFGYCKN
KGNTFVPCEEKDLKCGKIYCSGGRPSSRLGEDKAYNLKNVKQNVTIKCRTMFLHHNSRDM
GLVNSGTKCGDGMVCSNGECIEMEKAYNSTICSSPCDENDVDDNEPECQCEEGSIITEWG
EALNLTSVSIMVIVLVMVIIGVGLVILLIRYQKCIKMKQVQSSPREIRGVENKGYFPEEH
QTRSEPILTDIHPLHTTAESLERVPSSFSSPHYITLKSVSKDSRGIADPKQTDNVNLNLD
TQSGCERLG

>Rattus norvegicus_ADAM7(ENSRNOP_19209)
MFPTGIFLMSVLISQMQGRGIVGVEGQELVHPKKLSLLQKRDLERIHDSDTPEEYEEELL
YEIKLGRKTLTLHLLKAREFLALNYSETYYNIKREMVTRHPQILDHCFYQGSIIHEFDSA
ASISTCNGLRGFFRVNDQRYLIEPVKYSDEGDHLVFKYNVKAPYATNYSCEGLNFTKKST
LIDAKNIEEHKVEDYHKEKFIELFVVADEFVYRRNSKPQNKLRKRIWGMVNFVNMIYKAL
NIRVTLTGMEIWSAGDEIEIVSNLESTLLHFSTWQETVLKKRKDFDHVILLSGKWLYTSM
QGIAYPGGICQTLRSCSVVKDLLPDVNIIGNRMAHQLGHSLGMRHDDFPCTCPLGKCVMG
AGSIPAIKFSKCSQTQYQQFLKNQKPACILNNPLPEEFNDYPFCGNKKVDEGEECDCGPV
QECTNPCCDAHKCVLKPGFTCVEGECCESCQMKKEGVICRPAKNECDISEVCTGYSPECP
KDESQANGFPCKNGEGYCFMGLCPTRDDQCAELFSGGAEESHSLCYRMNQKGNRFGYCKN
KDNTFVPCEEKDLKCGKIYCTGGRRSAHLGEDKTYNLKNVKQNISIKCKTMFLYHNSRDM
GLVNSGTKCGEGMVCSNGECIEMEKAYNSTICSSLCDENDVDDNEPDCQCEEGPIITEWG
EALNLTSVSIMVVVLVMVIIGVGLVILLIRYQKCIKMKQVQSSSREIRGIENKVYFPDEH
QTRSEPIFTDIYPLHNTAESLERVPSTFSSPHYITLKSVSKDPRGIADPKQNDNMNLNLD
SQSDCTRLG

>Canis familiaris_ADAM7(ENSCAFP_13324)
MFLRSLLFMIILISQIKEKVIIGVEGQEVVYPKKLPLMQKREVWHIHDYDIQETYEEELL
YELRLTRKTLILHLLRSREFLGLNYSETYYSTKGEMITSYPSTTDHCFYQGSIIHEFDSA
ASISTCNGLRGFFRVYDQRYLIEPVKYSDEGQHLVFRYNPKMQYAANYSCTELNFTRKND
PKDDIKIMEDLKIERIHKEKYVELFIVADNNVYRRNSSPLSNLRNRIWGMVNFVNMIYKI
LDIHVTLVGLEIWTNEDKVHIDSNIENTLLRFSTWQEIILKKRNNFDHVLLLSGKWLYTH
AQGTSFSEGICLPYYSSSVVKDLLPDLNVVASRIAHQLGHNFGMKHDDYPCTCNFERCVM
DRGGSIPAIKFSKCNRIQYLQHLKNYNPTCMFNIPFSDKLSDYPYCGNKKLDEGEECDCG
SIQECTNPCCDANKCVLKPGFTCAEGECCESCQQMKKSGSICRPAKDECDFPEVCTGHST
ACPQDKFQVNGFPCKNAKGYCFMGKCPTRDDQCSEFFDNEVKDSSDLCYEMNKKGNRFGY
CKNKENSLIPCEEKDVKCGKIHCSRGQHSSLLGKEKINHLKKISKQNVTAECKTFILYHN
SKDLGLVAPGTKCGDGMVCSNGECMKLEKVYNSTNCSSQCNENAVDGHDLQCQCKEEQEH
VDWEENLNVTNISILAVMLVLVIFGVGVVILLIHYQKCIKLKQIQSPPTDSLGVENKGYF
GDDQQTRTEPILPNIHPLHQRTAESLERLPTSFSSPHYITLKPANKDPRGIADPNQSSKM
NLKLDIQNGCARLG

>Monodelphis domestica_ADAM7(ENSMODP_20913)
FQEKYDVEVLYEMILHGKQMVLHLRKTEDLVSPNYSETHYSQGGEEITTNPKLMDHCYYQ
GHILHEKDSAASISTCDGLRGYFRQHDQRYLIEPLEHTDQGEHAIFKYDHKAQDRTNGSC
VVYNFSKTEAITQASRSTLKMQIYLKEKKYIELFIVADHALYRRHNHLQKWLRTRIFGMV
NFVNMLYKTLNIQVILVGLEMWTNGDKIEVNSNLGTTLLSFGGWQETTLKKRKNYDHAQL
LSGNWLSQTAQGTAYPWGMCVPFHSSSIVKDHLHDTNMVADKMAHELAHNLGMQHDSYPC
TCTYGRCVMDGGGSIPSQGFSKCNRNQYRQYLLDYKPMCILNVPLSKDIITFPKCGNQIL
EVGEECDCGSLEDCTNICCEAKKCTLKPGSTCGGGKCCESCQQIKKAGTLCRRAKDECDL
PEVCDGFSPKCPVDRFQLNGFPCQNSEGYCFMGKCPTRDSQCSEMFKDEAKGSHDICYER
NKGGHKFGYCKRVDNKFIPCDEKDLKCGKIYCTGGQYFPTYGEDKNYHLKVPDENITVEC
KAFFPFQYTEDIGLVALGTKCGDGKVCKNGECVNIETVYDSTNCSSQCPGQSVCDHELQC
QCEEGLTHPKCEDNTLITNVSIVAGVLTVVLATIVIAVLFVRRKKASKQKQVNSSPPPTT
PGADNQGHSSEGQRQTRTAPLVCTQDVLNQNATDTFEDIPPGYSSPQYITMKSANKETRR
IPAYNQNVR

>Homo sapiens_ADAM8(ENST_445355)
MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPWRLPGPRVRRALPSHLGLHPERVSYV
LGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQDHCFYQGHVEGYPDSAAS
LSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHLLQTAGTCGVSDDSLGSLLGP
RTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSEAAVRHRVLEVVNHVDKLYQKL
NFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQARQRTRRHLHDNVQLITGVDFTGTT
VGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAG
RCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLVGGPVCGNLFVERGE
QCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTCCQECKVKPAGELCRPKKDMCDLEEFCD
GRHPECPEDAFQENGTPCSGGYCYNGACPTLAQQCQAFWGPGGQAAEESCFSYDILPGCK
ASRYRADMCGVLQCKGGQQPLGRAICIVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKG
RCQDLHVYRSSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVFVVV
VLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPS
RGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFA
PPVPPVKPGAGAANPGPAEGAVGPKVALKPPIQRKQGAGAPTAP

>Mus musculus_ADAM8(ENSMUSP_101684)
MLGLWLLSVLWTPAVAPGPPLPHVKQYEVVWPRRLAASRSRRALPSHWGQYPESLSYALG
TSGHVFTLHLRKNRDLLGSSYTETYSAANGSEVTEQLQEQDHCLYQGHVEGYEGSAASIS
TCAGLRGFFRVGSTVHLIEPLDADEEGQHAMYQAKHLQQKAGTCGVKDTNLNDLGPRALE
IYRAQPRNWLIPRETRYVELYVVADSQEFQKLGSREAVRQRVLEVVNHVDKLYQELSFRV
VLVGLEIWNKDKFYISRYANVTLENFLSWREQNLQGQHPHDNVQLITGVDFIGSTVGLAK
VSALCSRHSGAVNQDHSKNSIGVASTMAHELGHNLGMSHDEDIPGCYCPEPREGGGCIMT
ESIGSKFPRIFSRCSKIDLESFVTKPQTGCLTNVPDVNRFVGGPVCGNLFVEHGEQCDCG
TPQDCQNPCCNATTCQLVKGAECASGTCCHECKVKPAGEVCRLSKDKCDLEEFCDGRKPT
CPEDAFQQNGTPCPGGYCFDGSCPTLAQQCRDLWGPGARVAADSCYTFSIPPGCNGRMYS
GRINRCGALYCEGGQKPLERSFCTFSSNHGVCHALGTGSNIDTFELVLQGTKCEEGKVCM
DGSCQDLRVYRSENCSAKCNNHGVCNHKRECHCHKGWAPPNCVQRLADVSDEQAASTSLP
VSVVVVLVILVAAMVIVAGIVIYRKAPRQIQRRSVAPKPISGLSNPLFYTRDSSLPAKNR
PPDPSETVSTNQPPRPIVKPKRPPPAPPGAVSSSPLPVPVYAPKIPNQFRPDPPTKPLPE
LKPKQVKPTFAPPTPPVKPGTGGTVPGATQGAGEPKVALKVPIQKR

>Rattus norvegicus_ADAM8(ENSRNOP_24369)
MLGLWLLSILWTPAVAPGPPLPHVKQYEVVWPRRLAASRSRRSLPSQWGLYPESLSYALG
TSEQVFTLHLRKNRDLLGSSYTETYSAANGSEVKEQLHEQDHCLYQGHVEGYEGSAASIS
TCAGLSGFFRVGSTVHLIEPLDADEEGQHAVYQAKHLEQKAGTCGVSETSLDKLGPRTLE
IYRAQPGNWLKPREIRYVELYVVADSQEFQKLGTREAVRQRVLEVVNHVDKLYRELSFRV
VLVGLEIWNKDKFYISRYANVTLENFLSWREQNLLGRHPHDNVQLITGVDFIGTTVGLAK
VSALCSRHSGAVNQDHTRSAIGVASTMAHELGHNLGMNHDENIPGCYCPIPREGGGCIMT
ESIGSKFPKTFSRCSQVDLESFVTNHQTGCLTNVPDVNRFVGGPVCGNLFVERGEQCDCG
TPQDCQNPCCNATTCQLAKGAECAHGACCHECKVKPAGELCRPMKDKCDLEEFCDGQKPT
CPEDAFQQNGTPCPGGYCFDGSCPTLAQQCQALWGPGARAASDSCFAFSIPQGCYGSMYP
SRINRCGVLFCEGGQKPLERSSCTFSSHHGLCQALQTDSNTNTYEFVLQGTKCEEGKVCM
DGNCQDLRVYRSENCSAKCNNHGVCNHKRECHCHAGWAPPYCAQLLADVPGEQAASESLP
VSVVVVLVILVAAVVIGAGIVIYRKAPKQIQRRSVAPKPTSGLSNPLFYTGDSSLPAKSR
PPDPPEMVSTNQPPRPIVKPKRPPPAPPGAMSSPPLPVPVYAPKAPNQLRPDPPTKPLPK
LKPKQVKPTFAPPTPPVKPGTGGTVPGVTQGAGGSKVALKVPIQKR

>Bos taurus_ADAM8(ENSBTAP_32645)
LGLLLFAALGLQEVAPRAALPHVEQYEVVRPRRLPAPRARRALPSHLGLYPESVSYVLGA
RGHTFTLHLRKNRDLVGSGYVETYTAANGSQVTEQLQRQDHCFYQGHVEGHPHSAASLST
CAGLRGFFQAGPAVRLIEPLAEAGEEGPHALYLAQHLQQEAGTCGVNDSSLESILGPRVS
AAFRPRKWSEPRETRYVELFVVTDSKEFQRFGSREAVRQRVLEVVNHVDKLYQELNFRVV
LVGLEMWNGGDKIQISSQPDATLDNFLAWRTRELVGRQAHDNVQLITGVDFTGTTVGLAK
VSTMCSSSSGAVNQDHSQNPIGVASTMAHEMGHNLGMDHDENVAGCYCPVPREGGGCVMA
ASIGSQYPRKFSQCSQADLETFVENPRTACLLDAPDLDRLVGGPVCGNGFLERGEQCDCG
RPEDCQNRCCNASTCLLAEGAECAHGTCCHECRVKPAGELCRPVKDQCDLGEHCDGQQPT
CPEDAFRENGTPCPGGYCYNGACPTLARRCQDLWGPGSRVAVETCFLYSISKGCGAGVPL
PFGRVNKCGTLFCEGGQKTPERGYCTLTISSGVCRVIVQDGSTEYEPVPKGTKCGEQQVC
WDGFCQGLHVYRSRNCSAQCNSHGECNHKGQCHCRPGWAPPHCAEPLADARAAPTAPGSL
RTHVLVGVGALVVLALILAGVLIYRKARSPVRRRNVAPKTAMGLSNPLFHEGLSKPAKGG
AQAPPGGSPELALYSQPHKPTASSVTPKRPPPAPPAAKASPPSPLPVYPPQAPGQLRPAP
PAKPLPVLKPKQVIKPTCAPPMPPIKPGARGAQPGPTQGAADPKVALKPPVQRR

>Gallus gallus_ADAM8(ENSGALP_5435)
PVGTWHVPLLGSPGVGAGLREELAHVERYETTVPRRVPSPRAKRDLSVSTSTYPEHVLYS
VCAEGRDYLLHLEKNRELLGQRYTETHYLADGTEVTVKPDVQDHCFYQGHVEGHANSAAS
ISTCSGLSGFFRVNETVFLLKPLDEHEAGQHAVYRASHLRMKRSACLEAALEYDHDPKIA
APLKLYHWKSARLHRGPRYVELVLVVDNEEFRKYKDLRRVQNRMKEIVNHVDKLYQSLGL
RVALIGLEVWSNRDKITVSRKAEETLENFLRWREMDLLKRKQHDNVQLITGIDFHDTTVG
LAKKLAMCTRDSGGVNQDHSVDPIGAASTLAHEMGHNLGMSHDEDIADCRCPVSKERGGC
VMAAKISSAYPRLFSTCSEQDMWQFLEDPKTSCLLNVPGADELYGEPVCGNQFVERGEEC
DCGRPEECSDRCCNATTCRLREGAECARGDCCQDCKVKAAGVLCRASKNDCDLPERCTGL
SSECPEDVFQENGIPCQGGRGYCYNGACPSHAEQCRLLWGAGSTASHPTRCNPVPHPWRW
DVKCGTLLCMSDASSPALGSGFLTLSFGHYKCKAALDSNDDNEMTGSLQLVPTGTKCGEE
MVCYAGRCQNLLVYGKKNCSAKCSGHGVCNHKRECHCELGWAPPYCQHKVLELTAGASSM
VLAAVLAVLVLSSILIGGGFVLLRGKGKKYFQKGRISSRPTTGLTNPLFQEGARPHQLSL
RAIGSPSLLSTTAAPRDARPLVPGCPLLQDSSSAPKPGHCPMLRSLPGPQEKPKPPTKPL
PALKTKQVAGEALPPTPPAKPPALSFQPRAIPVLPQRGVPPKLALKPPASRR

>Danio rerio_ADAM8a(ENSDARP_1187)
MRYTGLFITLLSFVYTWESLEALPHVMRYDVVRLQALRGRTRRSASSLQKYPEQLEYDVA
IDGRNLTISLHRNRELLGKQYTLTHYGEDGISETKSSNKFNHCYYHGHIHNFEDSSVSVG
LCSGMEGFLRVNDQVYLIEPLEESLDGDHAIYKQEHLRTKRGAYGYINDTVYDLGPKSSG
LYKGKNMRNKAPRGGQQIVEMVLVVDNTEYKKFGSFKKIEERMMLVANHVDKLYRPLNIR
VMLVGLEVWSQRDLIDVSSRPNLTLERFLKWRRDSLLQRKKHDNAHFITGIDFEGSTVGL
ATLYAMCSSSSSGAVNEDHNSNPIAVASTVAHEMGHNLGMSHDDSSCGCSSNKGCIMGDT
IGSIYPDSFSTCSQSSLKAFLENYDTNCLIDVPNEGQIYGGPVCGNAFVEKGEECDCGTV
EECNNPCCNATTCRLTEGARCAHGECCHNCQLKHTGSLCRKSAHDCDLDEYCTGESAFCP
EDDYKMNGLPCNYNQGYCYNGQCPTHKEHCKMLWGSGADVDDDACFQYNVIDRTSKSAEH
RKCGRIYCYGGNPFPKTNKKANVNVQSRTCYMALDSSPTEDLGMVPTGTKCGTNKVCYKS
LCLDISMYGTENCSNKCNNRGVCNHELKCHCDPGWAPPYCDIQLSELHKMRKSVVIGVTT
SLAILVLIIIIGALVYNRNKITEFRKKRPQKGIHSSSGQCNPAFQPGSAKNSPRIAQPRI
SQPTFLESSATQACKPLRSAAMPCRPAPMPPKNAPQTRNEQIMKPPVPPSAISKNIYPPQ
AKPLLPAAKPLPPSRPLPPLASKAVTKSKSPPVPPVKPSGPQPVFTPPQVIQKVALKPPA
WPR

>Danio rerio_ADAM8b(ENSDARP_66470)
MPCPAFTAHILCWLCLCGCVAESIRTLPHVERFDVVRPKRLNLSKVQSDKNPPSHEKYPD
RLAYKLFFEGENHVIHLEKNKQLVGHNYTEIYYQDDGSIVSRNPSFKDNCYYHGHIQDME
YSSVSVGICSGIRGFVRVKQQVYLIEPLANHSDGDHALYKHQHLRRRRSSAGEPKTMFYD
HEPQVSAALKSSRWNMKSFQTPRFVELFLVVDNTEYRNFGSSMDSIRARMLEVVNHVDKL
YRSLNIRVMLVGLEVWMKQDQIVVSVSSDDTLSRFIEWRKSNLLKRVKHDNAQFVTGIDF
LGDTVGLANKFAMCAESSAGVNQDHNQNPLGLASTIAHEMGHNMGMSHDEDHCTCGSSVI
SSFCIMTERVGTLFPEQFSDCSLEQLTVFLDNANPSCLLDTPSSYKLYSGPVCGNAFLDP
GEECDCGSVEECKNPCCDPMTCKLTEGSRCAQGDCCENCQIKDAESLCRASINECDVPEY
CTGLSEKCPENDFRMNGIPCSSGQGYCYNGQCPTHLQHCQRLWGTGAKVAPDTCFYQNTL
GKNDSHCGKTKDGIRPCARENMFCGKIFCNEGNEFPVTGQKAVIVTLRGQCNVAGDQTEE
DALSMVPTGTKCGHNKVCYDYKCQELNIYGSIEGCSLQCNGRGICNHKKQCHCDPGWAPP
YCNVKYSELSSAKTIGISVAVAVAVLVVICGAVLYHKKRKAISRHKTQTPTSGQTSLLFE
NNSAQKDRPEISQPIFMGTTVSQPCTPLTARVGPTRPAPLPPKKPPSQPQQTTVTQGTKL
PAPPVPPVKPSLATGSWRNDHVTEDTVKVVLKPPIMPRR

>Takifugu rubripes_ADAM8(ENSTRUP_35665)
MTHSGCFLLVFFISWGITAGSVEPLPHVKKYQTVIPQRLKVSSPIHDAAAAHQTFPDVLR
YSVTFAEQNHTLHLEKNKDLVGGSFTVTHFTDEGTRVSTAPDLWDHCYYHGRVVGVDDSS
ASVGLCSGIKGFVRIQDQVYLIEPLADAEADVQGAKHSSEMPSDGGLHAVYNYKHLRRKR
SSCSHGNGTTFYDHGAHPSALFQKSRGQTRERAGKPRTVEMVVVVDHTEYKKFGSIKKVQ
SRVLEAANHVDKLYRPVGIRVMLVGLDIWSNRDQIDVSSDSELTLGRFLKWRQWKLLPDI
KHDNAQFITGVDFDGSTVGLANTNSMCTSNSGAVNEDHNPNPIGVASTIAHEMGHNLGLS
HDKENCVCGSQATKRGCIMSESLGIVYPEQFSSCSQQQLSTFLEEINPACLLDTPSTNRL
YGGPVCGNAFLEAGEECDCGTVEECTNPCCNATTCKLAAGARCAAGECCHGCQLKPTGSV
CREKSGDCDLEEFCTGFSASCPTDAFTQNGLTCNRGRGYCYNGQCPSRLQHCRRLWGPGK
SPANVLFRLIVLLFVLFGGRDQSCGKLFCSGGWEFPITSKKFFYTLGNGNLCNEAVMNSD
DNFPQDLAMVPTGTKCGTNMVCYNQRCQDIKSIKTYGTNDCAGKCSNRGVCNHENKCHCD
PGWAPPYCDVLLPELPEETGSMVVMVSLVTSLLLLVLVVGGSICCIKKTRPVKRCLRSAA
SGRSNPLFQPGSARGSPSLGPTHISQPIFVESSATRACKPLSSSRPTTAAPKPSRAAPED
YCLFFFLNPLQPPKNFKPAARPPQYQQPFPTQGKPLPPSRPLPPLASKPVTKPKLPVPPV
KPKPSAVPSSLPHTQLLAERAALMPPNRPR

>Tetraodon nigroviridis_ADAM8a(ENSTNIP_6193)
MADLGHFLFMLLVSWGTTSAEPLPHVKKYQTVIPQRLEDPSPSDDAAAHRTFPDVLRFSL
TITEQNYTLHLEKNKHLVGGSFTVTHFSDQGARVTTAPDLRDHCYYHGHVVGVEDSSASV
GLCSGIRGFVHVHGQIYLIEPLAEAETDGGLHAVYNYKHLRRKRSSCSHGNQTSYYDHVP
GPSGLFQLASLKRRGQSGERVGKPRTVELVVVVDHTEYKKIGSTKMVESRVLEVANHVDK
LYRPVGIRVMLVGLEIWSYRDLIDVSSDPELTLGRFLKWRQWSLLPRTKHDNAQLITGVD
FDGSTVGLANTNTMCTSNSGAVNEDHNKSPVGVASTIAHEMGHNLGLSHDVENCVCGSQT
TKRGCIMSESVGEAGLSIQGSSAAGSQQQLSTFLEEITPACLLDSPSTSRIYGGPVCGNA
FVEAGEECDCGTAKECRNPCCNATTCKLAAGAQCAAGECCHRCQLKATGSVCRPKSGDCD
LEEYCTGFSASCPRDAFTSNGLACNRGAGYCYNGQCPSHQQHCRRLWGPEAKMAVEACYL
QHGNCRKTLFNQKCSRRDQFCGKLLCSDGWEFPVTSKKFLYPLGNGKQCNEAGMNSEDNY
PPDLAMVPTGTKCGPNMVCYNQRCQDMKSVKPYATSDCSSKCNNRGVCNHENKCHCDPGW
APPYCDVLLSELPRETGSVVLPVSLAVGFLLLLVLVFGGLMCYIKKRPPVKRCLQSASGQ
SNPLFRSGSARGSPRLGPAHIGQPVFVESSATQACKPLFSSRATTAAPKPSRAAPEPPKN
PKPVAQPSQVQQVPRPPSSVGAEVSCCMQSLAPQKKPLPPSRPLPPVASKPVVKSKPPVP
PVKPKPSAYASSLPHTQLLAGRAALMPPNRPR

>Tetraodon nigroviridis_ADAM8b(ENSTNIP_14801)
VDGYEVVRPHRLVGRPRRTPGGHQIYPDTIRYKLPIEGRNLTIHLEKNRGLLGMGYTETH
YAEDGRRVTSLPEEEHCYYHGYVEGMEDSSVSVGLCSGISGFLRTQQQVYVIEPLRRSDQ
GEHAVFRREQLKVSGTPGCGLTLGTAYDAERGPKPANLKSRSWFSLVPPESERFVELFVV
ADNTEYKRHGSETRARIFTAVNHINKLYWALNIRVVLVGLEIWTYKDHFDVDGKSETTLD
RFLLWRQRDLLQRVKHDNAQFVTGKHFDGDTVGLANKFAMCTENSGGVNKDHHDNPIGLA
STIAHEMGHNFGLSHDAPGCTCGPPPGSSNCVMADKLSTGNLAFPEFFSDCSLEQLADFM
ARAQPSCLSKPPSSVKTEAVAPLCGNRLLDAGEECDCGTVEECDNPCCNPLTCYLTQGSQ
CSDGPCCENCQLKQAGSVCRVSAGECDLADYCTGASAECPEDGFEMNGKPCYNQVEGYCH
DGRCPTHQHHCWRLFGPGAVVGLDLCFNLNKQGISDSYDLFSDRNLKCGSIFCRGGGESI
TGKRTEYTVSGRECKQAVDDDKTRNLNMVPNGARCGPNKVCLDARCVDVSVYGVREDCAK
KCNNNGVCNHKKECHCNPGWAPPYC

>Gasterosteus aculeatus_ADAM8a(ENSGACP_8955)
MPDSGSFVWISLSLWGSVRTLPHVIKYQTVTPQRLWDPSAPDAATHQTYPDVLQYSLTIA
GRNYTLHLERNKDLVGKKFSVTHYSDQGTQVTTTPDLTAHCYYHGHIVGVEDSSASVGLC
SGINCRGFVRLRDQMYLLEPLAGTDEGLHAVYNYKHLRRKRSSCSHGNTTTFYDHGAHPS
GLFQLGSLKSRAQTKDPAGKPKTVELVVVVDNAEYKKFGSRKTVEARALEIANHVDKLYR
PVGVRVMMVGLDIWSYKDQIEVSADPELTLSRFLEWRQRSLLQRTKHDNAQFITGVDFIG
STVGLANTNAMCTSNSGAVNEDHNSNSIGVASTIAHEMGHNLGLSHDAENCVCGSPTSKR
GCIMAERVGLVYPELFSSCSQQQLSRFLEEINPACLLDTPAADRNYGGPVCGNSFLEPGE
ECDCGTVEECKNPCCNATSCKLNAGAQCAEGKCCHECQLKPTGSVCRPKAGNCDLAEYCT
GFSASCPTDAYTQNGLSCNRGKGYCYNGRCPSQREHCKRLWGPDADVASDACFYTHGNCK
RTLFSQRDQHCGTLFCSGGWEFPVTSRKSFYRVGNGDICNTATMIPEDNYPADLGMVPVG
TKCGNNMVCYNQRCQDIQNINTYGKSDCSAKCNHHGVCNHESKCHCDPGWAPPFCNVEQS
ELPEGILSQSVCVCVCAQMQVVGLLLLLVLVIGSLMCCIKKRRPAKRCLQANSGQSNPLF
RSSGTRGSPRLGSTHISRPIFVESTASKPLSSARPHAGVLTPCRAAPVPPKKLSALPQPM
KIQQAVRSFMQPVSSKPVYTENKPLPPSRPLPPLATKPIMKPTPPMPPVKPKPSAARCPL
PHTQLVWRAALTPPCRPR

>Gasterosteus aculeatus_ADAM8b(ENSGACP_5491)
LSHVEKYEVVRPQRLQGRPQRSPQDPQLHPDAVQYELTVEGTKHTILLEKNRNLIGRGFT
ETRYSQDGKRMTTSPKEELCFYHGHIRGLEDSSVSVGICSGISGLLRLRQQVFLIEPLGR
AADGDHALFRREHLKLGGPFACGSSPNGTTRHNPDRDPGPRLSGLFRSRSWKTKAVAGPQ
KFVELFVVVDNAEYKRYGDQTKSRILEVINHVDKLYRPLNIRVVLVGLEIWTDGDHIDVD
VKSETTLDNFLLWRRADLLRRTDHDNAQFVTGKDFDGDTVGLANKFAMCTENSGGVNQDH
HDNPIGLASTIAHEMGHNFGLSHDAAGCLCGPSHSSGTCVMAEKLRTGSQAFPELFSGCS
VEQLADFMERARPGCLRPPGSARSVAAGPRCGDALLDPGEECDCGTVEECKNRCCDASTC
LLTGGSQCAHGQCCDNCQLKPAGSVCREKASECDLSEFCTGASSDCPEDAFQMDGKPCFD
QGEGFCHSGRCPTHQQHCWRLFGKGATVGPPECFGLNRRGENKTVQVLFYRNLLCGSMFC
GGGGESISGKMAVYKVYGIECKLAVDDDRTRSLDMVPRGTRCGGNKVCLDRQCVDASAYG
RPEECAKKCNNNGVCNHKKECHCDPGWAPPHCDIQYADLPQGHSGIIAGVCAAVSILLLI
SALTAGLLCCKKDDMDNYASKRKVHSAPDRPDRVFQEQGVSGRPQISPPTFMASTATQAC
APLMVSAPPRAAAPQVPTRRGSTGEPQKAPPPKPPKAPPPAPPPAQTKPVPPSKPLPPLS
KTRVSHLMSGPAPPLLPAEP

>Oryzias latipes_ADAM8(ENSORLP_11654)
FKQNTLYVLLFIRLYLWCSKKTLPHVSKYQTVVPQRLKDLSTIKDTAPHEKYPDVLQYSL
SIDRGKYTLHLEKNRYLVGKNFTVTSYSDDGAQVTSTPDLRVHCYYHGHIVGVEESSASI
ELCSGMKGFVTLRNRMYLIEPLASDDEGPHAVYNYKHLRRKRSSCSHGNTTTFYDHGARP
SGVFQLGSLKSRAQTKQQADKPRTVELVVVVDNSEYKKYGSKKTIESRVLEIANHVDKLY
RPVGVRVMLVGLIIWSNRDQIEVSSNSDTTLIRFIEWRQRNLVQKIKHDNAQLITGIDFE
GTTVGLANTNAMCTSNSGAINEDHNTNAIGVASTIAHEMGHNLGLTHDTENCVCGSYTSK
RGCIMAESLGIVYPEQFSSCSKLQLRRFLEEYNPACLLDTPSTSRIFGGPVCGNAFLEPG
EECDCGSAKECTNPCCNATTCKLNAGAQCAEGECCHNCQLKPTGIICRPKAGDCDLAEYC
TGFSAACPADTFAQNGLRCNSGKGYCYNGNCPSRQEHCRRLWGPDAEVAADECFSRHGSC
RKFSQRCAAKDQFCGTLFCSGGWTFPVTSMKSYYIVGNGVTCNEATMKPEDNYPSDLGMV
PTGTKCGNNMVCYNNRCEDIRNIKAYGKNDCSSKCNNHGVCNHESKCHCDPGWAPPFCDV
QQSELTQDSAPVVVVVSVIIGLLLLLVLVVVSLMCYIRKRTPTKSRLTTSGQSNPVFRSS
GTRGGPPVGSKVISQPVFLESSATQACKPLSFALNRPDRDLKPCRAAPEPPKYTQGIPQP
TRKYQAFMQPTAVSLLPIYNENKPQPPSRPLPPLTAKPIMKPKLPTPPVKPKPTAALSSL
PHTQIGKRAVLMPPSRPR

>Homo sapiens_ADAM9(ENST_487273)
MGSGARFPSGTLRVRWLLLLGLVGPVLGAARPGFQQTSHLSSYEIITPWRLTRERREAPR
PYSKQVSYVIQAEGKEHIIHLERNKDLLPEDFVVYTYNKEGTLITDHPNIQNHCHYRGYV
EGVHNSSIALSDCFGLRGLLHLENASYGIEPLQNSSHFEHIIYRMDDVYKEPLKCGVSNK
DIEKETAKDEEEEPPSMTQLLRRRRAVLPQTRYVELFIVVDKERYDMMGRNQTAVREEMI
LLANYLDSMYIMLNIRIVLVGLEIWTNGNLINIVGGAGDVLGNFVQWREKFLITRRRHDS
AQLVLKKGFGGTAGMAFVGTVCSRSHAGGINVFGQITVETFASIVAHELGHNLGMNHDDG
RDCSCGAKSCIMNSGASGSRNFSSCSAEDFEKLTLNKGGNCLLNIPKPDEAYSAPSCGNK
LVDAGEECDCGTPKECELDPCCEGSTCKLKSFAECAYGDCCKDCRFLPGGTLCRGKTSEC
DVPEYCNGSSQFCQPDVFIQNGYPCQNNKAYCYNGMCQYYDAQCQVIFGSKAKAAPKDCF
IEVNSKGDRFGNCGFSGNEYKKCATGNALCGKLQCENVQEIPVFGIVPAIIQTPSRGTKC
WGVDFQLGSDVPDPGMVNEGTKCGAGKICRNFQCVDASVLNYDCDVQKKCHGHGVCNSNK
NCHCENGWAPPNCETKGYGGSVDSGPTYNEMNTALRDGLLVFFFLIVPLIVCAIFIFIKR
DQLWRSYFRKKRSQTYESDGKNQANPSRQPGSVPRHVSPVTPPREVPIYANRFAVPTYAA
KQPQQFPSRPPPPQPKVSSQGNLIPARPAPAPPLYSSLT

>Pan troglodytes_ADAM9(ENSPTRP_34552)
MGSGARFPSGTLRVRWLLLLGLVGPVLGAARPGFQQTSHLSSYEIITPWRLTRERREAPR
PYSKQVSYVIRAEGKEHIIHLERNKDLLPEDFVVYTYNKEGTLISDHPNIQNHCHYRGYV
EGVHNSSIALSDCFGLRGLLHLENASYGIEPLQNSSHFEHIIYRMDDVYKEPLKCGVSNK
DIEKETAKDEEEEPPSMTQLLRRRRAVLPQTRYVELFIVVDKERYDMMGRNQTAVREEMI
LLANYLDSMYIMLNIRIVLVGLEIWTNGNLINIVGGAGDVLGNFVQWREKFLITRRRHDS
AQLVLKKGFGGTAGMAFVGTVCSRSHAGGINVFGQITVETFASIVAHELGHNLGMNHDDG
RDCSCGAKSCIMNSGASGSRNFSSCSAEDFEKLTLNKGGNCLLNIPKPDEAYSAPSCGNK
LVDAGEECDCGTPKECELDPCCEGSTCKLKSFAECAYGDCCKDCRFLPGGTLCRGKTSEC
DVPEYCNGSSQFCQPDVFIQNGYPCQNNKAYCYNGMCQYYDAQCQVIFGSKAKAAPKDCF
IEVNSKGDRFGNCGFSGNEYKKCATGNALCGKLQCENVQEIPVFGIVPAIIQTPSRGTKC
WGVDFQLGSDVPDPGMVNEGTKCGAGKICRNFQCVDASVLNYDCDVQKKCHGHGVCNSNK
NCHCENGWAPPNCETKGYGGSVDSGPTYNEMNTALRDGLLVFFFLIVPLIVCAIFIFIKR
DQLWRSYFRKKRSQTYESDGKNQANPSRQPGSVPRHVSPVTPPREVPIYANRFAVPTYAA
KQPQQFPSRPPPPQPKVSSQGNLIPARPAPAPPLYSSLT

>Mus musculus_ADAM9(ENSMUSP_81048)
MGPRALSPLASLRLRWLLACGLLGPVLEAGRPDLEQTVHLSSYEIITPWRLTRERREALG
PSSQQISYVIQAQGKQHIIHLERNTDLLPNDFVVYTYDKEGSLLSDHPNVQSHCHYRGYV
EGVQNSAVAVSACFGLRGLLHLENASFGIEPLHNSSHFEHIFYPMDGIHQEPLRCGVSNR
DTEKEGTQGDEEEHPSVTQLLRRRRAVLPQTRYVELFIVVDKERYDMMGRNQTAVREEMI
RLANYLDSMYIMLNIRIVLVGLEIWTDRNPINIIGGAGDVLGNFVQWREKFLITRWRHDS
AQLVLKKGFGGTAGMAFVGTVCSRSHAGGINVFGQITVETFASIVAHELGHNLGMNHDDG
RECFCGAKSCIMNSGASGSRNFSSCSAEDFEKLTLNKGGSCLLNIPKPDEAYSAPSCGNK
LVDPGEECDCGTAKECEVDPCCEGSTCKLKSFAECAYGDCCKDCQFLPGGSMCRGKTSEC
DVPEYCNGSSQFCPPDVFIQNGYPCQNSKAYCYNGMCQYYDAQCQVIFGSKAKAAPRDCF
IEVNSKGDRFGNCGFSGSEYKKCATGNALCGKLQCENVQDMPVFGIVPAIIQTPSRGTKC
WGVDFQLGSDVPDPGMVNEGTKCDAGKICRNFQCVNASVLNYDCDIQGKCHGHGVCNSNK
NCHCEDGWAPPHCDTKGYGGSVDSGPTYNAKSTALRDGLLVFFFLIVPLVAAAIFLFIKR
DELRKTFRKKRSQMSDGRNQANVSRQPGDPSISRPPGGPNVSRPPGGPGVSRPPGGPGVS
RPPGGPGVSRPPPGHGNRFPVPTYAAKQPAQFPSRPPPPQPKISSQGNLIPARPAPAPPL
YSSLT

>Rattus norvegicus_ADAM9(ENSRNOP_44741)
MGPRALSPLASLRLRWLLACGLLGPVLEAGRPDSEQTVHLSSYEIVTPWRLSRERREALR
PSSKQISYVIQAQGKQHIIHLERNTDLLPNDFVVYTYDEEGSLLSDHPNVQSHCHYRGYV
EGVPNSTVAVSACFGLRGLLHLENASFGIEPLHNSSHFEHVFYPMDDVHQEPLRCGVSNR
DTEQEATQGEEEEHPSVTQLLRRRRAVLPQTRYVELFIVVDKERYNMMGRNQTAVREEMI
RLANYLDSMYIMLNIRIVLVGLEIWTDRNPINIIGGAGDVLGNFVQWREKFLITRRRHDS
AQLVLKKGFGGTAGMAFVGTVCSRSHAGGINVFGQITVETFASIVAHELGHNLGMNHDDG
RECFCAAKSCIMNSGASGSRNFSSCSAEDFEKLTLNKGGSCLLNIPKPDEAYSAPSCGNK
LVDPGEECDCGTPKECELDPCCEGSTCKLKSFAECAYGDCCKDCQFLPGGSMCRGKTSEC
DVPEYCNGSSQFCPPDVFIQNGYPCWNSKAYCYNGVCQYYDAQCQVIFGSKAKAAPRDCF
IEVNSKGDRFGNCGVSGSNYKTCATGNALCGKLQCENVQEMPVFGIVPAIIQTPSRGTKC
WGVDFQLGSDVPDPGMVNEGTKCDAGKICRNFQCVNASVLNYDCDIQGKCHGHGVCNSNK
NCHCEDGWAPPHCDTKGYGGSVDSGPTYNAKSTALRDGLLVFFFLIIPLVAAAFFLFIKR
DELRKTFRKKRSQMSDGRNQANASRPPGDPSVSRPPGGPSVSRPPGGPNVSRPPGGPNVS
RPPGGPSVSRPPPVHGNRFPVPTYAIKQPPQFPSRPPPPQPKIPSQGNLIPARPAPAPPL
YSSLT

>Canis familiaris_ADAM9(ENSCAFP_8762)
MGSGAGSPFGVFRLQWLLLFGTVGPVLGGARPGFQQTSHLSSYEIITPWRLTRERREAPR
PYSEQVSYIIQAEGKEHIIHLERNKGFLPRDFVVYTYNKEGALISDHPDVQNHCHYRGYV
EGISNSSIALSDCFGLRGLLHIENVSYGIEPLQNSSHFEHIFYRMDDVHKEPLKCGVSNK
DMEKETTNYEEEEPLSVTQLLRRRRAVLPQTRYVELFIVVDKERYDMMGRNQTAVREEMI
RLANYLDSMYIMLNIRIVLVGLEIWTNGNLINIIGGAGDVLGNFVQWREKFLITRRRHDS
AQLVLKKGFGGTAGMAFVGTVCSRSHAGGINVFGQITVETFASIVAHELGHNLGMNHDDG
RDCFCGAKSCIMNSGASGSRNFSSCSAEDFEKLTLNKGGNCLLNIPKPDEAYSAPFCGNK
LVDPGEECDCGTPKECESDPCCEGTTCKLKSSAECAYGDCCKDCWFLPGGTLCRGKTNEC
DVPEYCNGSSQFCQPDVFIQNGYPCQNNKAYCYNGMCQYYDAQCQVIFGSKAKAAPRDCF
IDVNSKGDRFGNCGFSGNEYKKCATGNALCGKLQCENVQDMPVFGIVPAIIQTPSKGTKC
WGVDFQLGSDVPDPGMVNEGTRCDNGKICRNFQCVNASVLNYDCDIQKKCHGHGVCNSNK
NCHCENGWAPPNCETKGYGGSVDSGPTYNEKNTALRDGLLVFFFLIVPLIVCAAFVFIKR
DQLWRSYFQKKRSQTSDGKNQAKASRQPVSVPRHVSSVTPPSGSSVFTMPVGTKQVWRYI
FGRFLFKPIYANRFPVPTYAAKQPQQFPSRPPPPQPKVSSQGNLIPARPAPAPPLYSSLT

>Monodelphis domestica_ADAM9(ENSMODP_28755)
DFQQTSLLSSYEIITPWRLVRERREAPRPYSAQVSYVIQAEGRKHVVHLERNKILLPKDF
VIYTYSEEGSLLLDHPDMQDHCHYHGYVEGVPNSAVALSICSGLRGLLHLENTSYGIEPL
KSSSDFEHLIYRLDNVQQEPLACGVTAKDLKKETTEDEKKELQKQSLSMTQLLRKKRAVL
PHTRYVELFIVVDKEKYDMMGSNQTAVREEMVQLANYLDSMYIMLNIHIVLVGLEIWTNS
NQISIAGSAGDVLGNFVQWREKSLISRRRHDSAQLVLRKGFGGTAGMAFVGTVCSRSHAG
GINVFGQISVETFASIVAHELGHNLGMNHDDGRNCTCGAKSCIMNSGASGSRNFSSCSAD
DFENLTLNKGGTCLLNIPKPDEAYSAPYCGNKLLDVGEECDCGSPKECELDPCCEPSTCK
LKSGAECAYGDCCKNCRFLPGGTLCRPSANECDLPEYCNGSSQFCQLDVYIQNGYPCHKN
KAYCYSGMCQFYDAQCQVIFGSKAKAAPRDCFIDVNSKGDRFGNCGHNGNEYRKCSTGNA
LCGKLQCENVQGMPVFGILPALIQTVFGGTTCWGVDFQLGSDVPDPGMVNEGTKCDHGKI
CRNFQCVNASVLNYDCDTQKKCSGRGVCNNNKNCHCNMGWAPPNCENTGYGGSVDSGPTY
NGKNTSLRDGLLVFFFLIVPLLVFAAFVFLKRDQLRRKFFRKKRSQTYHSRRRQVVLRPV
GELARYPSPKYVKTSPGEMSGSDGKNQTNVSRQPANAPRNAPPAIYANRFPVPTYAAKQP
QQFPSRPPPPQPKVLSQGNFIPTRPAPAAPVKGLL

>Gallus gallus_ADAM9(ENSGALP_5363)
GFQEISQLSSYEVIIPQKLGRERRETSNASSTQDKVSYAIEIEGKEYTIHLEKNKDLLPK
DFTVYTYNKEGKLQSEYPDVQDHCYYQGYVEGILDSVVAVSTCSGLRGLVTIGNVTYGIE
PMDSSSGSEHIVYSLDNVKKEPSMCGVMTEGHEEGEHTGENHHPSMTQLLRKKRAILHQT
RYVELFIVVDKEKFEDFGKSETEVREHMVQLANFLDSMYIMLNIHIVLVGLEIWKYENII
STDGGAGDVLANFVQWREKNLVLRRRHDSAQFVLKKGFGGTAGMAYVGTVCSKSHAGGIN
VFGKISIQMFASIMAHELGHNLGMNHDDERVCHCGASSCIMSSGASGSRNFSSCSAEDFE
KLTLNKGGSCLLNVPRPDETYSIPYCGNKLVDMGEECDCGSPKECENDPCCEPGTCRLRP
TAECAYGDCCKNCRILPGGTECRASNNECDLPEYCNGTSQFCQPDFTVQNGHPCHNEEAY
CYNGVCQYYDAQCQDIFGSKAKAAPNICFAKVNSKGDRFGNCGFHGHDYKKCSSWNAMCG
KLQCENVETMPVFGIKPAIIRTPSDGTTCWGVDFQLGSDVPDPGMVNEGTKCDNGKVCRH
FQCVSASVLNYDCDVEKQCHGHGVCNNNRNCHCEPGWAPPFCNTKGYGGSIDSGPPYNDK
DNSLRNGLLVFFSWSYHSL

>Anolis carolinensis_ADAM9(ENSACAP_9070)
MFLYVITIEGKDRTLVLERNEVLLPKDFTMYTYKKDGTLHTEKPRIEDHCHYQGYVEGTS
DSLVAVNICFGLRGMIQIGNITFGVEPTHTGKHVVYPLSSVKSPFFSCGVHSLSHGCKSP
AMFHSVEDRTPHLRNKRGLLLQTRYVELFIVVDKERYMLLGQNKTAIREEMMHLANYLDG
MYATLNIRIVLVGLEIWTVQNKISLEGGAADVLANFVQWRERDLILRRRHDSAQLVMTKG
FGDVAGMAYVGTICSKSNAGGINVFGPISVQMFASIVAHELGHNLGMNHDDERHCHCPTD
NCIMKSKASGARNFSSCSEEDFEKLTLNKGGSCLLNIPRPEETYSIPYCGNKLVDAGEEC
DCGSLEECKTDPCCEPGMCKLRPGAECGYGDCCHNCHYMTKATECREKASECDLPEYCNG
TSAFCPQDVTIQNGHPCKKGEAYCYNGVCQYYEAQCQAIFGPKAKAAPEVCFSAVNSKGD
RFGNCGYHNYDYKKCSSSNSMCGKLQCENVKTLPVFGIEPAFIQSPIKGSTCWGVDFQLG
SDVPDPGMVNEGTKCAPGKICKHYQCVDVAVLGYDCDINNQCNGQGVCNSNKNCHCNSGW
GPPFCNTKGYGGSVDSGPPYNDEDTTTRNWLLAFFFLILPLLLSVVFCYFMRNRLGYSLR
PLIECCCGCFRRSRRRRQEPVGSEFPPNVPFPPMDTSSQMNMQAKRYPVPSYTANQQPYG
EHFYYAPPHSAPRSAALPTEQHYIPSRPPPPATKPTKTQEPLIPSRPAPLPPK

>Danio rerio_ADAM9a(ENSDARP_122318)
MAHAVCSRLVKNAFMWIMLHTLVDCCGGSVTQQTSQLSSYEVTVPRRISRQRRNQDSADK
VSYIIQAQGKEHVVILERNELLLPEDFTVYSYAKDGSLVTEKLNTTDHCHYSGYIEDVEG
SSAALSLCSGLRGVIHTEGTSFGIEPLEGSSSDEHLVYRLEDVQTQPLNCGTPHSYNHDD
QSSPRQPIISHTHNITFGQAGSHLRRKRAVLHQTHYVELLMVVDNERYNYKNRNHTAVRE
EVVQIANYVDSMYIPLNIRIVLVGLEIWNMQNLINIDGSAGEVLSRFTQWREKELVHRRR
HDSAQLILKKGFGGTAGMAFVGTACSRSHGGGINAFTNNNVMSFASIVAHELGHNLGMNH
DDGRNCKCDVTHCIMNSGATGSCNFSSCSADDFEKMILNSGGRCLLNIPRPDEAYSAPFC
GNKLVDVGEECDCGSEEECEKDPCCEAKTCKLRSGAQCAYGVCCKNCRFLPGGSVCRSST
DECDLAEYCNGSSALCQNDVFKQDGHPCKQDTAYCYNGQCQHYDTQCQNIFGKKAKAAPE
LCFKDVNSKGDRFGNCGYHSSGFKKCESRNAMCGKLQCENVFSLSVIFGIKPARIETPIA
GTTCWGVDFRLGSDVPDPGMVNEGTKCGDNKVCLNFECRSADVLNYDCDVEKKCHGHGVC
NSNKNCHCEYGWAPPFCEASGYGGSIDSGPTWNDKDTSLRDGLLVFFFLVLPLLALGLYV
FFKRNELKQRFLRKKRSQAYEDESRPQATVSQRGIPKSIVKDGHQTQLLPPEEVVYTNKS
ASVPSYATRPPPPPFTRPPAPHQQPKPQRPAPAPPV

>Danio rerio_ADAM9b(ENSDARP_74097)
MTRHVNIFVLILINFSICPVQAIDQTSYLKKYDVVKPQLVQMRWRRYADPSHKQPEERHA
DIITYSVRIEGSDRILHVTKNTDFLSKNFVVISHKTPKKGKVQPERMVQCYYQGHVEGYE
DSLVALSTCEGIRGVIIIGNKSYGLEPVLHSKANEHLLFLLEDSHSEPFVCGLENETSLS
EDHSRYADMSMFLRKKRTLPQTKYVELALVVDQKRFIIKNRSVNAVRDEMVQLANLLDTY
FKQLNIRIALIGLKIFDTGNPFSVEGNAGDVLGRFVDWRKTTLSPQIRNDAAQLVVGQGA
YPGGVLGMAFVGSVCSASTSGAISVFSDNNLQYYSTVAAHELGHNLGMSHDSNGCSCQCI
MAPSASGSTKFSDCSDNAFERLIQGGGGACLRNIPAQDSIISVPRCGNGILESGEECDCG
TPQECNTTCCNAATCTFTKGSTCAAGSCCQKCQIIVAGTPCRPSINPCDLPEYCGGESPY
CPSDFYMMDGLPCNNNAAYCFEGRCQTFDYQCKQIFGSGATKADDKCFTNVNTYGNAFGN
CGYSGTFPKPCSVQNAMCGKLQCLFNSNNPPLGATVSVQKIEGGTITCMNADFNMGPDVP
DPAYVKTGSVCAPGKLCANFTCFNSSVMDQSRKCDAQRDCSSNGVCNDRYHCHCNNGWGP
PNCNKGGRGGSIDSGPAEIDYSLRNGLLIFFLLVVPILVVLIIVLLYVFKRDSLKRFLKG
CPSIRKRPTNAANGSSNTPSNVQANGNTTRASAPQSMTEIQTAHQSQPTDPKYQQDTTVN
QPRQGPGVPKPIPPRQTQVPV

>Takifugu rubripes_ADAM9(ENSTRUP_30568)
QTQHLSSYQLTVPRPVGGRFRREANGTLPSQVSYIIPVDGLDHIVHLQRNQLLLPADFTV
FSYSQNGSLITSRPPVQNHCHYHGFVENMPESSVAMSICNGLRGVLRLPDNSYGIEPLES
DPNQHLLYRLQDVTSQPQGCATSHGDRHYDPTEEIPHTRQHKRMKRAVLHQTHYVELLLV
VDNDRFNYMNRNDTAVREEMVHLANFIDSIYIQLNVRVVLVGLEIWTQQNLISTDGGAGE
VLSRFTQWREKALVPRRRHDSAQLILKKSFGGTAGMAFVSTVCSRSHGGGINAFPNTNLP
AFASIVAHELGHNLGMNHDDGRSCTCPTAACIMNSGTTESRNFSSCSADDFEKMILLTGG
TCLLNVPHPDEAYSSPYCGNRLVDVGEECDCGSQKECEKDPCCEYQTCKLKPGAQCAYGE
CCSGCQYLAGGTVCRSSTDECDLPEFCNGSSSLCQSDVFVQNGQPCRSQQAYCYNGKCRH
HDGQCQDIFGSKAKASPEICFKDVNNKGDRFGNCGYHNYGYKKCESRNALCGKLQCSNIQ
TSIVFGIQPSIISTSIGGAKCYGVDFRLGSDVPDPGMVNEGTKCGEDKVCVNFECRSADI
LNYDCDVEKKCHGHGVCNSNKNCHCDDGWAPPFCELQGYGGSVDSGPTWNDKDTSLRDGL
LVFFFLILPLLILTAFVYLRKNEFLRCLGLQRRKRSEAYQVDKATPVNRSRGPPPRVPPP
VSLGNSDNVVETSRTAPAFAPRPPPPPLKPKPPPASHPLVPQRPAPAPPVYSSLS

>Tetraodon nigroviridis_ADAM9a(ENSTNIP_706)
VDGREHVVRLQRNRLLLPADFTVFSYSQNGSLVTARPPVQNHCHYQGFVENMLGSSVAMS
ICNGLRGVLHLHDDSYGIEPLESDPDQHLLYRLQDVTSQPKGCGTAHGGGPHSPAQDVLH
TGLHKRVAMKRAVLHQTHYVELLLVVDNERVNPLKLMPDCCARVCVCACASIIYIQLNVR
VVLVGLEIWTHQNLISTEGAAGEVLSRFTQWREKALVPRQRHDSAQLILKKSFGGTAGMA
FVSTVCSRSHSGGINAFPNNNLPAFASIVAHELGHNLGMNHDDGRSCTCPSPACIMNSGT
TYGRGDSRNFSSCSADDFEKMILLTGGSCLLNVPHPDEAYSAPYCGNRLVDVGEECDCGS
QKECEDDPCCEHQTCRLKPGAQCAYGECCSGCQRARAQYLAGGTVCRSSTDECDLPEYCN
GSSSFCQSDVFVQNGQPCSSQQAYCYNGKCQHHDGQCRDIFGSKAKASPEICFRNVNSKG
DRFGNCGYQNYGYKKCESRRNALCGKLQCSNIQTSIVFSIQPSIISTFIDGANCYGVDFQ
LGSDVPDPGMVNAGTKCGDERVCINFECVSAQVLSYDCDVEKKCHGRGVCNSNRNCHCGD
GWRRPSASSRDKDTSLRDGLLVFFFLVLPLLALGTFLYLRRNDLVRRL

>Tetraodon nigroviridis_ADAM9b(ENSTNIP_22615)
SKFTLKLSKYSVVNPEVTQRWKRNIESEPNQKHGEETMSFALKINNRRHLIHLKKNRDFL
HPNFAQYSHNRTGNHKSPAQKSPRHCYYHGEVEGYENSVVALSTCAGLRGVIILDNETYV
LEPVPQSATNDHLLYLLRDVQSEPFTCGVDDEAAASGHGHEHFNAGLLFQQRKRNLPQTS
YVELVLVVDNLRYNFKKQNETAVREETVELANLLDGYYKMLNIRVMLIGLVIFKDSNPFS
VEGSAGDVLGRFVDWRKTSLLPKLRHDIGQLIVGRPESYGGVLGMAFVGTVCSASTSGGI
NVFSDNSLPYFSTVVAHEMGHNLGMTHDDERCKDGSYIMASTAGGSTTFSRCSADDFEAL
IIRGGGLCLNNQPSASDVIGIAECGNGRLESGEDCDCGKPEECNNKCCDAATCKFTSGSA
CAQGRCCDNCQXKVNRKTCRESDNTCDLTEYSNGTNQFCQNDYYAMDGLPCGDAYCYEGR
CQTYDFQCRHLFAPDPATKANDICFQTANTKGNLFGNCGMTSAGQFIKCSVENAMCGKVQ
CTNVDLSSIPTGAHVSIQIVQGFKCINADFNLGSDVLDPAYVNPGSPCDKGKTCIDFQCV
NASALLPNLNCDAQTTCHGHGVCNNDGHCHCENGWGPPNCDRPGRGGSVDSGPAQIDYSL
RNGLLIFFLLVVPIMIVVILGLLYFFRRESL

>Gasterosteus aculeatus_ADAM9a(ENSGACP_1421)
QQTEHLSSYQLTVPRPMGGRLRRDTAGRLPNQVSYSISVDGNDHIVHLERNEWLLPADFT
VFSYSQNGSLITSRPPVQDHCHYLGSVQDMEGSAVAMSICNGLRSLIHLPTNSLVCFPPA
DSQQTEHLSSYQLTVPRPMGGRLRRDTAGRLPNQPPGVRLVLQMKRAVLHQTHYVELLLV
VDNDRYNYLNKNETAVRDEMVHLANFVDSIYKQLNVRVVLVGLEIWTQQNQISTDGGAGE
VLSRFTQWREKELVPRRRHDSAQLILKKSFGATAGMAFVSTVCSRSHGGGINVFIGNNIA
SFASIVAHELGHNLGMNHDDGRSCSSSVEACIMNSGATGSINFSKCSADDFEKMMLLTGG
SCLLNVPRPDEAYSAPSCGNRLVDVGEECDCGTQKVRLCTSNPCCEYHTCKLRPGAQCAY
GECCYKCQIIITGNVLRASTDECDLPEYCNGSSSLCQIDVFIQNGHPCRTHQAFCYNGKC
QHYDGQCQAIFGSKAKAAPEICFKDVNSKGDRFGNCGYHNYGYKKCESRNALCGKLQCSN
VQAVTVFGIEPSIISTPIAGGKCYGVDFMLGSDVPDPGMVNEGSKCGDNQVCVNFECSSV
DALNYDCDVEKKCHGHGVCNSNRNCHCDDGWAAPFCEVKGYGGSVDSGPTWNENDTSVRD
GLLVFFFLVLPLLALGAFVFLRKDELLRRLGLRRRKRSQGYQADAATSANPSRGPPPRAP
PPPVTHGNNIVKDGVVETSRTASSYALRPPPPPHKPKLSVASHPLVPQRPAPAPPV

>Gasterosteus aculeatus_ADAM9b(ENSGACP_3255)
SKYSIVNPQVVDRLKRNLNRPTQSEEKYGKETISYSVNINNRKHLLHLKKNRDFLHPNLV
QYSSDAIGNHNTSYPKPHVHCYYHGQVEGHEDSVVALSTCSGLRGVIFLGNETYGLEPVP
QSTNNEHLLYLMKDIESGPATCGVVNEAASTQSHEPFEPGTSLTSLLRIKQRKRNLPDTR
YVELVLVADNLRYQFKKQNETAVREELVQIANLLDGYYKQLNIRVVLVGIQIFKGSNPFN
VDGSAGQVLGDFVRWRRDVLLPRIRHDDAQLIVGQPNAYNGNILGMAFVGTVCHVGTAGG
INVFSANNLLLASVVVAHEMGHNLGMMHDRDGCSCNGTSRCIMGAAVGGVSTFSSCSGQD
FENLIVRGGGTCLKNQPSPSDVVGVAECGNGRLEEGEQCDCGKPGECNNKCCDAATCKLT
SGSACAQGGCCSNCQIKVAGTPCRGSANTCDLPEYCNGTAGFCPNDFYVMDGLPCQDSQA
AAYCYEGRCQTYGFQCKQLFAPGPATKAADICFQNANMRGNTFGNCGIGTNGVPIRCTLA
NSMCGKLQCTNVDVNNPPPGAQISVEVLGKEKCINVDFNLGTDVLDPGYVNSGSPCENGK
TCIDFKCVNASALLPKLNCDARATCNSKGVCNDRGNCHCENGWAPPNCDRAGRGGSIDSG
PAQIGGDHSLRDGLLIFFLLVVPVL

>Oryzias latipes_ADAM9a(ENSORLP_21844)
MMSGGVKLLEVFSLLLLLSGNSDCRDFEQTEDLSSYQLTVPRPIGGRLRRDVDGRPPEQV
SYVIAVDGTDRVVHLERNHLLMPADFTVFTYSENGSVIASRPAVQDHCHYRGFVQDVGGS
SVAMSICNGLRGVMHLTDESYGIEPLDSAPDQHLLYLLRDVTSQPQGCGTRHERSNVTEH
AQPKPTEVHHGEHRRMKRAVLHKTHYVELLLVVDNDRYNYMNRNQTAVRDEMVHLANFVD
SIYVQLNVRVVLVGLEIWTHQNPISTEGEAGEVLSRFTQWREKELVPRRRHDSAQLILKK
SFGGTAGMAFVSTVCSRSHGGGINAFTNNRIPAFASIVAHELGHNLGMNHDDGRTCSCPV
DACIMNSGTTGSRNFSSCSADDFEKMILVTGGMCLMNVPRPDEAYSAPYCGNGLVDVGEE
CDCGSEKECEEDPCCEYKTCKLKSWAQCAYGECCYKCRYLPGGTVCRSSEDECDLPEYCN
GSSPLCQSDVFIQDGQPCRNQKAYCYNGKCQYHDKQCQALFGTKAMAAPEICFKEVNSKG
DRFGNCGYQNFPFKKCESRNALCGKLQCSNVQGVTVFGKVPSYITTRIGGAECYGVDFNL
GSDVPDPGMVNEGTKCGDNKVCMNFECRSADILKSDCDTEKKCHGHGVCNSNRNCHCSSG
WAPPFCELSGYGGSVDSGPTWNDKDTSLRDGLLVFFFFVLPLLGLGAFVFLRRNELLRRL
GLSRRKRSQGYEPDAAASGRQSREPPPRHHAQLLPPKEVAEPNRTTPPHPARPTPHPVRP
SGPPLKPKPSAASQPLVPQRPAPAPPV

>Oryzias latipes_ADAM9b(ENSORLP_11894)
SSTRFLNKLATLAIRWYGIKPNMAQNTLLSKYSIVKPQVIHRWARSIKIQKHSDESVSYA
VSINHRRHVLHLKRNRGFLHSNVLRSLHGASGSDNSSHPRRHVHCYYHGKVEGYNNSMLA
LSTCYGLRGVIVLENDTFGIEPVPKSSTNEHILYHLNDTQYKTATCGVVNEAGSSPSYKP
FEPDQMLVSLLRRKRNLPETSYVELVLVVDNLRYRFKDKNATAVRDEMVELANLLDGYYK
ELNIRIILVGLEIFKDTNPFSVEGSAGDVLERFVKWRKSTLIPKIRHDIGQLIIGPPQDY
GNILGMAYVGTVCSVASSGGINLFKSQSLASFSTVVAHEMGHNLGMNHDGDNCDCGGGNC
IMAPSAGGSTKFSQCSETYFENLILRGGGGCLRNQPSPSDVIGTAECGNGRLDEGEDCDC
GKPTECKNKCCNAATCTFTRGSACADGRCCENCQIKVAGWPCRKSVDSCDLPEYCDGKKA
FCPTDFYMMDGLLCQNNAAYCYEGRCQTYDYQCRHLFAPDNARKAEDICFKTANTKGDKF
GNCGPEPGGSGYLKCSVANSMCGKVQCTNVDVNTPPTGAQVSIQQIQGATCVNADFNFGT
DVLDPAYVNPGSPCDTGKTCVDFKCVNASVLLPDLDCDAKTTCNGHGVCNDRGHCHCDNG
WGPPFCDKSGWGGSIDSGPAQDYSLRNGLLIFFFLVVPLLVLLILVLLYIFKRDSLDVCL
KRFRYGELDYWRHETNNPPPRPPPPGGRPPRPSPPVQGPGVPKP

>Homo sapiens_ADAM12(ENST_368679)
MAARPLPVSPARALLLALAGALLAPCEARGVSLWNQGRADEVVSASVGSGDLWIPVKSFD
SKNHPEVLNIRLQRESKELIINLERNEGLIASSFTETHYLQDGTDVSLARNYTVILGHCY
YHGHVRGYSDSAVSLSTCSGLRGLIVFENESYVLEPMKSATNRYKLFPAKKLKSVRGSCG
SHHNTPNLAAKNVFPPPSQTWARRHKRETLKATKYVELVIVADNREFQRQGKDLEKVKQR
LIEIANHVDKFYRPLNIRIVLVGVEVWNDMDKCSVSQDPFTSLHEFLDWRKMKLLPRKSH
DNAQLVSGVYFQGTTIGMAPIMSMCTADQSGGIVMDHSDNPLGAAVTLAHELGHNFGMNH
DTLDRGCSCQMAVEKGGCIMNASTGYPFPMVFSSCSRKDLETSLEKGMGVCLFNLPEVRE
SFGGQKCGNRFVEEGEECDCGEPEECMNRCCNATTCTLKPDAVCAHGLCCEDCQLKPAGT
ACRDSSNSCDLPEFCTGASPHCPANVYLHDGHSCQDVDGYCYNGICQTHEQQCVTLWGPG
AKPAPGICFERVNSAGDPYGNCGKVSKSSFAKCEMRDAKCGKIQCQGGASRPVIGTNAVS
IETNIPLQQGGRILCRGTHVYLGDDMPDPGLVLAGTKCADGKICLNRQCQNISVFGVHEC
AMQCHGRGVCNNRKNCHCEAHWAPPFCDKFGFGGSTDSGPIRQADNQGLTIGILVTILCL
LAAGFVVYLKRKTLIRLLFTNKKTTIEKLRCVRPSRPPRGFQPCQAHLGHLGKGLMRKPP
DSYPPKDNPRRLLQCQNVDISRPLNGLNVPQPQSTQRVLPPLHRAPRAPSVPARPLPAKP
ALRQAQGTCKPNPPQKPLPADPLARTTRLTHALARTPGQWETGLRLAPLRPAPQYPHQVP
RSTHTAYIK

>Pan troglodytes_ADAM12(ENSPTRP_50102)
GVSLWNQGRADEVVNASVRSGDLWIPVKSFDSKNHPEVLNIRLQRESKELIINLERNEGL
IASSFTETHYLQDGTDVSLARNYTVILGHCYYHGHVRGYSDSAVSLSTCSGLRGLIVFEN
ESYVLEPMKSATNRYKLFPVKKLKSVRGSCGSRHNTPNLAAKNVFPPPSQTGARRHKRET
LKATKYVELVIVADNREFQRQGKDLEKVKQRLIEIANHVDKFYRSLNIRIVLVGVEVWND
MDKCSVSQDPFTSLHEFLDWRKMKLLPRKPHDNAQLVSGVYFQGTTIGMAPIMSMCTADQ
SGGIVMDHSDNPLGAAVTLAHELGHNFGMNHDTLDRGCSCQMAVEKGGCIMNASTGYPFP
MVFSSCSRKDLETSLEKGMGMCLFNLPEVRESFGGQKCGNRFVEEGEECDCGEPEECMNR
CCNATTCTLKPDAVCAHGLCCEDCQLKPAGTACRDSSNSCDLPEFCTGASPHCPANVYLH
DGHSCQDVDGYCYNGICQTHEQQCVTLWGPGAKPAPGICFERVNSAGDPYGNCGKVSKSS
FAKCEMRDAKCGKIQCQGGASRPVIGTNAVSIETNIPLQQGGRILCRGTHVYLGDDMPDP
GLVLAGTKCADGKICLNRQCQNISVFGVHECAMQCHGRGVCNNRKNCHCEAHWAPPFCDK
FGFGGSTDSGPIRQADNQGLTIGILVTILCLLAAGFVVYLKRKTLIRLLFTNKKTTIEKL
RCVRPSRPPRGFQPCQAHLGHLGKGLMRKPPDSYPPKDNPRRLLQCQNVDSSRPLNGLNV
PQPQSTQRVLPPLHRAPRAPSVPARPLPANPALRQAQGTCKPNPPQKPLPADPLARTTRL
THALARTPGQRETGLRLAPLRPAPQYPHQVPRSTHTAYIK

>Mus musculus_ADAM12(ENSMUSP_65213)
MAERPARRAPPARALLLALAGALLAPRAARGMSLWDQRGTYEVARASLLSKDPGIPGQSI
PAKDHPDVLTVQLQLESRDLILSLERNEGLIANGFTETHYLQDGTDVSLTRNHTDHCYYH
GHVQGDAASVVSLSTCSGLRGLIMFENKTYSLEPMKNTTDSYKLVPAESMTNIQGLCGSQ
HNKSNLTMEDVSPGTSQMRARRHKRETLKMTKYVELVIVADNREFQRQGKDLEKVKQRLI
EIANHVDKFYRPLNIRIVLVGVEVWNDIDKCSISQDPFTSLHEFLDWRKIKLLPRKSHDN
AQLISGVYFQGTTIGMAPIMSMCTAEQSGGVVMDHSDSPLGAAVTLAHELGHNFGMNHDT
LERGCSCRMAAEKGGCIMNPSTGFPFPMVFSSCSRKDLEASLEKGMGMCLFNLPEVKQAF
GGRKCGNGYVEEGEECDCGEPEECTNRCCNATTCTLKPDAVCAHGQCCEDCQLKPPGTAC
RGSSNSCDLPEFCTGTAPHCPANVYLHDGHPCQGVDGYCYNGICQTHEQQCVTLWGPGAK
PAPGICFERVNSAGDPYGNCGKDSKSAFAKCELRDAKCGKIQCQGGASRPVIGTNAVSIE
TNIPQQEGGRILCRGTHVYLGDDMPDPGLVLAGTKCAEGKICLNRRCQNISVFGVHKCAM
QCHGRGVCNNRKNCHCEAHWAPPFCDKFGFGGSTDSGPIRQADNQGLTVGILVSILCLLA
AGFVVYLKRKTLMRLLFTHKKTTMEKLRCVHPSRTPSGPHLGQAHHTPGKGLLMNRAPHF
NTPKDRHSLKCQNMDISRPLDARAVPQLQSPQRVLLPLHQTPRAPSGPARPLPASPAVRQ
AQGIRKPSPPQKPLPADPLSRTSRLTSALVRTPGQQEPGHRPAPIRPAPKHQVPRPSHNA
YIK

>Rattus norvegicus_ADAM12(ENSRNOP_24974)
MAERPARRAPPARALLLALAGALLAPRAARGVSLWDQRGAYEVAKASLLTKDPGSPGQSI
PAKDHPDVLTVQLQLESRELILSLERNEGLIANGFTETHYLQDGSDVSFTRNYTDHCYYH
GHVQGDAASVVSLSTCSGLRGLIVFENKTYILEPMKNTTDRYKLVPAENMKNIQGLCGSH
HNKSSLTMEDVFPEPSQMWGRRHKRETLKMTKYVELVIVADNREFQRQGKDLEKVKQRLI
EIANHVDKFYRPLNIRIVLVGVEVWNDIDKCSISQDPFTSLHEFLDWRKLKLLPRKSHDN
AQLISGVYFQGTTIGMAPIMSMCTAEQSGGVVMDHSDSPLGAAVTLAHELGHNFGMNHDT
LERGCSCRMAAEKGGCIMNPSTGFPFPMVFSSCSRKDLEASLEKGMGMCLFNLPEVKQAF
GGRKCGNGYVEDGEECDCGEPEECTNRCCNATTCTLKPDAVCAHGQCCEDCQLKPPGTAC
RGSSNSCDLPEFCTGTAPHCPANVYLHDGHPCQGVDGYCYNGICQTHEQQCVTLWGPGAK
PAPGICFERVNSAGDPYGNCGKDSKSSFVKCELRDAKCGKIQCQGGASRPVIGTNAVSIE
TNIPQQEGGRILCRGTHVYLGDDMPDPGLVLAGTKCAEGKICLNRQCQNISVFGVHKCAM
QCHGRGVCNNRKNCHCEAHWAPPFCDKFGFGGSTDSGPIRQADNQGLTVGILVSVLCLLA
AGFVVYLKRKTLMRLLFTHKKNTMEKLRCVHTSRTPSGPRPGQAHHILGKGPLMSRPPHF
NTTKDRHSLKCQNIDISRPLNARVVPQPQSPQRVLLPLHQAPRAPSGPARPLPANPAVRQ
AQGTHKPSPPQKPLPADPLSRTSRLTGALVRTPGQQESGHRPAPIRPAPKHQVPRLSHNA
YIK

>Bos taurus_ADAM12(ENSBTAP_16524)
MAARPPPAPPARALLLALAGALLAPRAARGVNLGSQFVPSMQQAGTRDGAGAYEVVSVSL
LNGDPWNPMKTADSENHPGVLNFRIQLTSKELIVNLERNEGLIASSFTETHYLQDGTDIS
LIRNYTGHCYYHGRVQGSFGSAVSLSTCSGLRGLITFENNTYILEPMKNATNRYKLFPVE
NLPGTWGSCGSNTSGLTLHDRLPLASQTQTRRQKRETLKMTKYVELVIVADNREFQRQGK
DLEKVKQRLIEIANHVDKFYRPLNIRIVLVGVEVWNDIDKCSISQDPFTSLHEFLDWRKM
KLLPRKSHDNAQLISGVYFQGTTVGMAPIMSMCTAEQSGGIVMDHSDSPLGAAVTLAHEL
GHNFGMNHDTLERGCSCKTAADKGGCIMNPSTGFPFPMMFSSCSRKDLEASLQKGMGMCL
FNLPEVKQSFGGQKCGNGYVEEGEECDCGEPEECQNLCCNATTCALKPDAVCAHGLCCEN
CRLKPAGTACRDPSNACDLPEFCTGASPHCPANVYLHDGHPCQGVDGYCYNGICQTHEQQ
CVTLWGPGAKPAPGICFERVNSAGDPYGNCGKDSKSSFAKCAMRDAKCGKIQCQGGASRP
VIGTNAVSIETNIPLQEGGRILCRGTHVYLGDDLPDPGLVLAGTKCADGKICLNRRCQNV
SVFGVHECAVQCHGRGVCNNRKNCHCEPHWAPPFCDRFGFGGSTDSGPVRQADNQGLTIG
ILVTILCLLAAGCVVYLKRKTLIRLLFTDKKNTIEKLRCVRPPRPPRGSQPGQAHLTHLS
KGPTRKPPPSSTPKDNTRRVPPCQHVDISRPLKAPDAPWPSSPQRGLPPLHQAPRVPCVP
ARPLPANPALRQAQGTRKPSPPQKPLPADPLSKTARLAGAPARSPGRQESALRLAPIRPA
PKQPHPVPRPAPIAYAK

>Monodelphis domestica_ADAM12(ENSMODP_13206)
FLFQDHPVGLSFRIEVDGQELIIHLERNEVTQARLSFQRSSSGCGYILSHKSLRIVLGHC
YYHGHVQGHPDWTVSLSTCSGLRGLILLGSQAYILEPLKGAAGKYKFQPAETLKPAWGSC
GQQQLNGSGRTVTKKISFILFWQHKRETLKTTKYVELVIVADNREFQRQGKDVEKVKQRL
IEIANHVDKFYRPLNIRIVLVGVEVWNDIDKCSISQDPFTSLHEFLDWRKMKLLPRKPHD
NAQLVSGVYFQGTTIGMAPIMSMCTAEQSGGVVMDHSDSPLGAAVTLAHELGHNLGMNHD
TLERGCHCQSTTDKGGCIMNPSTGYPFPMMFSSCSKRDLETSLQKGMGMCLFNLPNIKES
FGGQKCGNGYVEEGEECDCGEPDECTNPCCNATTCTLKPEAVCAHGLCCENCQLKPAGTA
CRASSNSCDLPEFCTGANPHCPANVYLHDGHRCHRVDGYCYNGICQTHEQQCITLWGPGA
KPAPGICFERVNSAGDPYGNCGKDSKSSFAKCAMRDAKCGKIQCQGGASRPVIGTNAVSI
ETNIPLQEGGKILCRGTHVYLGDDLPDPGLVLAGTKCEDGKLCLNRRCQNVSVFGVHECA
TKCHGRGVCNSNKNCHCEADWAPPFCDKPGFGGSVDSGPIRQAGKRGLTVAVLVTLLCLG
AAGLVTYLKRKTLIRLLFTNKKTKTTIEKLRCVSPARPSGVVEPNRTRTTNLSHGVLRKP
PPTNTSKENCRRLPKYQNIDISNPVKTLDSSLALHQGPSHQNVPVRPLPANPPTRQTQGT
QKPSPPQKPLPADPLSKATRPHETSRRTSGQPEPGHRIVPIRPAPQGPPQVPRAWYSAGM
K

>Gallus gallus_ADAM12(ENSGALP_43249)
MSKRLLAERQRSPAPRPSVLLLSLSALLLASPRARGREALLCLGLELNFCSPFVFLTSHQ
SSVLEGQNVDSKLESLRQQMLKDQSKDYEITVPLLLNGEQWRPANSIYSKNHPSLLQLVV
QAEGERLVIHLERNEGLLASSFTETHYLKDGTDVVLSRNYTGHCYYHGNVRGYPSSSVSL
STCSGLRGIIVFENKSYILEPLEGATSEHKIYRAENLEIIPGSCGHQLDISATRAADPSH
RSQGGRYKRETLKTTKYVELVIVADNREFQRQGKDVEKIKQRLIEIANYVDKFYRPLNIR
VALVGVEVWNDMDKCSISQDPFTSLHEFLDWRKLKLLPRKPHDNAQLISGVYFQGTTIGM
APIMSMCTAEQSGGVVMDHSENPLGAAVTLAHELGHNFGMNHDTLERGCNCKASTDKGGC
IMNPSTGYPFPMVFSSCSRKDLENSLEKGVGMCLFNLPEVKESFGGQKCGNGYVEDGEEC
DCGEPDECTNRCCNATTCTLRPGAVCAHGLCCEDCKLKPAGISCRESSNSCDLPEFCTGA
SPHCPANVYLHDGHACHGVDGYCYNGICQTHEQQCITLWGQGAKPAPGICFERVNSAGDP
YGNCGKDSKSSFAKCEPRDAKCGKIQCQGGANRPVIGTNAVSIETNIPLQEGGKILCRGT
HVYLGDDMPDPGLVLSGTKCEDGKICLNRRCQNTSVFGVHKCATKCHGRGVCNNKKNCHC
EADWAPPYCDKPGFGGSVDSGPIRQADNKSLTVGVLITILCLTFAGSVMYLKRKTLMRLL
FTSKKTTIEKLRSVSPARSSRSSKLNHVRTTSLSKNLMMKPQNANVQKRDGPRRPLPYQI
VDISDPVKTHHVPQLKTPQRVLPPLPQPPCHQAGPERPLPANPTLRLPQENHKPSPPRKP
LPADPLNKTRYNSACTPGLGHTKALPHIAPARPAPKHPPPVPRSSNATADVK

>Anolis carolinensis_ADAM12(ENSACAP_730)
MSRRLQAGREASLTALFPPHTRRWCCCCLQLLSLASFLFPPAAGTQGGDAESKLKFSRQW
IPKNKPEQYEITVPYFMNGQHWKPMKNVYPQIHPARLKFLIQVEREQLVISLERNDGLFA
GNFTETHYLEDGTGAVLMRNYTNHCYYHGHVQDYAISAVSMSTCFGLRGLISFEDKAYIL
EPLEGATNEHIIYRATSLKLAPGSCGHHLNISAITLEDTVQSIQTFTSRHKRDALKSTKY
VELIIVADNREFQRQGKDVEKVKLRLIEMANYVDKFYRPLNIRIALVGVEIWNDADKCAV
TQDPFTTLHEFLDWRKLKLLPHKPHDNAQLVSGVYFQGTTIGMAPILSMCTAEQSGGIVM
DHSDSPLGAAVTLAHELGHNFGMNHDTLERGCNCKASADKGGCIMNPSTGYPFPMMFSSC
SKKDLENSLEKGVGMCLFNLPEVKESFGDPKCGNGYVEEGEECDCGELEECTNQCCNATT
CTLRSGAFCAHGLCCENCMLKPAGILCRDASNSCDLPEFCTGGSPHCPANVYLHDGHSCH
RVDGYCYNGMCQTHEQQCITLWGQGAKPAPGICFERVNSAGDPYGNCGKDSKGSFAKCEA
RDAKCGKIQCQGGANRPVIGTNAVSIETNIPLQEGGRILCRGTHVYLGDDMPDPGLVLIG
TKCADGKICLNRHCQNTSVFGVHECATKCHGRGVCNNKKNCHCEAHWAPPFCDKAGFGGS
VDSGPLRQSDNQSLIIGLLITILCLLIAGLLMYVKRKILIRLLFINKKTTIEKLRSVTPA
RPSSSFEPNHFPTATLNKNLDQKPQNLYTHKRNDPQRMLKYQAGDISKPVKTQDRWRSSP
PERALPSLCELPCQHSVPRKLLPAIPSPRHEQESCKPSPPRKPLPADPQKSKSAHFTNAS
RAAHEFPKPVCQLSSVRPAPKHLLHGHRSCNAAYKQ

>Danio rerio_ADAM12(ENSDARP_99354)
MRIHRRMESWYLMNGLRAFVLLVVGLTADISTHHSPDERQLRSVLTKLEHYHTMVPLLLE
GTEQRPISWLRSRTPPASLHILIQTEGQQLILSVEKNHGLFASHYTETHYREDGQTVTST
HNSTMNCYYHGEVQGYVHSEVTLSTCSGIRGFVLLENKTLMVEPAFEPANDTHVIYDGHH
LHFPSGTCGHGHNISTVSNTNTRGLLQSFRTRHKRDVQKTTKYVELIIVADNREFQKQGK
DVEKVKQRLAEIANYVDKFYRVLNIRVALVGLEVWSDVDKCSVTQDPFTTLHEFLDWRKL
KLLPQRPHDNAQLISGVYFQGTTIGMAPIMSMCTAEQSGGIVMDHSDNALGAAVTLAHEL
GHNFGMNHDTPERGCGCRMTVDRGGCIMTPSTGYPFPTVFSTCSKKDLVASLEKGVGMCL
YNMPEVKMLYGGQKCGNGYIEEGEECDCGEPEECLNPCCNATTCTLKGDAVCAHGQCCEN
CQLKPAGTPCRESSNSCDLPEFCTGTNPHCPANVYLHDGHACHNMDGYCYNGICQTHEQQ
CITLWGPGAKPAPGICFERVNSAGDPYGNCGKDAKGSFAKCEARDARCGKIQCQGGANRP
VIGTNAVSIETNIPLQEGGRLLCRGTHVYLGDDMPDPGLVLAGTKCAEGKMCLNRQCQNV
SVFGVHKCSAKCNGRGECNNKKNCHCEAHWAPPFCDRAGFGGSVDSGPMRQAADSSAVAV
GSLVTLLCLLSAGLMLCLKRKALVQFLCANKKNAIQKLRSVGRKQTPSPPQTQSVFRVSP
QHKPPSLPLHSRADKMSHPSSEPLLPAHSFQSLRRMPECPSRCQPVHISHPMPITLQPHR
TLRATVVHTLPRHIAYTHTQDHDMPSPPQKPLPAHPLIRSHGMGRNVRIPAPLAIPIPTV
PRPPPSIPLPNRPLPRLPQPFYDH

>Takifugu rubripes_ADAM12(ENSTRUP_8992)
TENYESTIPLLLKGKDPRPLSQLRTRGYPASLRLLVQAEGEKLILLLEKNEGLFASHFTE
THYREDGSAVTSAHNVTNNCYYHGKVQAHPNSDVTLSTCSGLRGFIMLDNRTLVIEPASG
RDSDVHFIYRVENLRLTQGDCGHGYNMTSVPLENHIKNPFHSFHTRQKRHAQRTTKYVEL
IIVADNREFQKQGSDVEKVKQRLAEIANYVDKFYRPLDIRVALVGLEVWSDSDKCPVTQD
PFATLHEFLDWRKVKLLPQRPHDNAQLISGVYFQGTTIGMAPIMSMCTVEQSGGIVMDHS
ENPLGAAVTLAHELGHNFGMNHDTPERGCGCRMTVDRGGCIMTPSTGYPFPTVFSTCSKK
DLAASLEKGVGMCLYNMPEVKVLYGGQKCGNGYVEEGEECDCGEPEECMNPCCNATTCTL
TGDAVCAHGQCCDDCKLKPAGTLCRESGNSCDLPEFCTGASPHCPANVYLHDGHACHSVE
GYCYNGICQTHEQQCITLWGAGAKPAPGICFERVNSAGDPYGNCGKDTKGSFAKCDARDA
KCGKIQCQGGANRPVIGTNAVSIETNIPLQEGGRILCRGTHVYLGDDMPDPGLVLAGTKC
GDGLVCLNRQCQNVSVFGVHECSGKCNGRGVCNNKNNCHCEAHWAPPLCEREGFGGSIDS
GPMRLAADSAVITVAILITLASLLTVTIAVFVKRKTLLRLLFANKKSTLEKFRYTERVRS
GKASSPRLIGPSLLSAEPLLPPHNFHSHSLRRLPLYQPLHISGPMPASLSVGQPTLPPLP
AHHRVPLAAASLSPTQTFFQDFEKPSPPQKPLPADPLGRSARLGRGTTAGTHVPGNGPLP
IPIPTVPRPAPTMPLPS

>Takifugu rubripes_ADAM12(ENSTRUP_21275)
GLFASNYTETHYLEDGTVVTGTHDFTANCFYHGEVEGHINSDVSLSTCTGVKGYISLEDT
SYVLEPSPEHTDGTHWIYTAEHLGLAAGTCGHHSNLSSPGGAAESSPFRTFGSRHKRHVQ
TTTKYVELIIVADNREFQKQGKDMEKVKQRLAEIANYVDKFYRALNIRVALVGLEVWSDV
DKCPITQDPFTTLHEFLDWRKVKLLPQRPHDNAQLISGVYFQGTTIGMAPIMSMCTAEQS
GGIVMDHSDNPLGAAVTLAHELGHNFGMNHDTPERGCGCRVTADRGGCIMTPSTGYPFPT
VFSSCSKKDLTASFEKGVGMCLFNMPEIKVLYGGQKCGNGYVEEGEECDCGELEECMNPC
CNATTCTLKGDAVCAHGQCCQGCQLKPAGTPCREPSNSCDLPEFCTGSSPDCPANVYLHD
GHACHNVDGYCYNGICQTHEQQCITLWGQGAKAAPGICFQRVNSAGDPYGNCGKDSKGSF
AKCEARDAKCGKIQCQGGANRPVIGTNAVSIETNIPLQEGGRILCRGTHVYLGDDMPDPG
LVLTGTKCGEGLMCLNRQCQNVSVFGVHECSAKCSGRGVCNNNKNCHCEAHWAPPFCDKA
GFGGSVESGPIRLTDSRNLTVGILVALLTVLGAGLIICVKRKTLQGLLFTSKKNPMEKLR
SISADANRAAAAPSQPPAVSTASPSRPAPPPPHSSKVFNLRPLPQCPPVHLSHPVPVSLT
LSLSPGPMQPRPPVPPPHVHVGGRARHGSCRMVMEMEKPSPPQKPLPADPRSTRVVRSPS
VVQGHILVQGPSVVCGPPTAPRVPTPVRPALHPKRPSPKHPPTLP

>Tetraodon nigroviridis_ADAM12(ENSTNIP_3878)
NCFYHGEVEGHINSDVSLSTCAGVKGLISLEDTSYVLEPSSDHTDGTHWIYTAEHLRLAG
GTCGHDFNTSSSVEDAVSSPFKTSAQGHKRHVQATTKYVELIIVADNREFQKQGKDMEKV
KQRLAEIANYVDKFYRALNIRVALVGLEVWSDVDKCPITQDPFTTLHEFLDWRKVKLLPQ
KPHDNAQLISGVYFQGTTIGMAPIMSMCTAEQSGGIVMDHSDNPLGAAVTLAHELGHNFG
MNHDTPERGCGCRVTADRGGCIMTPSTGYPFPTVFSSCSKKDLTASFEKGVGMCLFNMPE
IKVLYGGQKCGNYVEEGEECDCGRTNEECLNPCCNATTCTLKGDAVCAHGQCCQDCQLKP
AGTPCRESSNSCDLPEFCTGSSPHCPANVYLHDGHACHNVDGYCYNGICQTHEQQCITLW
GQGAKAAPGICFQRVNSAGDPYGNCGKDSKGSFAKCETRDAKCGKIQCQGGANRPVIGTN
AVSIETNIPLQEGGKILCRGTHVYLGDDMPDPGLVLTGTKCGEGLMCLNRQCQNVSVFGV
HECSAKCSGRGVCNNNKNCHCEAHWAPPFCDKSGFGGSIESGPIRLADGRSMTVGVLVAL
LIVLGAGLIICLKRKTLQGLLFTSKKNPIEKLRCVSIELGPARMREAVAGLTFVASPQHR
LEPVLPPAPYPSHSLRRLPQCPPVHLSHPVPVSLTLSLSPGRMQPRPPVPPPHVHAGARA
SPLRGAPRNGSCRMVMEMEKPSPPQKPLPADPRSSRLVRSPSAVQGRGGPVQGPAVLFYL
RPSSRPSPKHPPTLPKPCFVANVK

>Gasterosteus aculeatus_ADAM12a(ENSGACP_12696)
GLFAGHYTETHYREDGSSVTGAHNFTLIENNCYYHGEVQSHPGSDVTVSTCTGLRGFIAL
ENKTFIIEPVSGHDNGAHFIYRVEELKLTPGACGHGFNASSVAPENHIQNPFQSFHARHK
RHAQKTTKYVELIIVADNREFQKQGRDVEKVKQRLAEIANYVDKFYRALNIRVALVGLEV
WSDSDKCPVTQDPFSTLHEFLDWRKVKLLPGKPHDNAQLISGVYFQGTTIGMAPIMSMCT
AEQSGGIVMDHSENPLGAAVTLAHELGHNFGMNHDTPERGCGCRMTADRGGCIMTPSTGY
PFPTVFSTCSKKDLAASLEKGVGMCLDNMPEVKVLYGGQKCGNGYVEEGEECDCGEPEEC
MNPCCNATTCTLKGDAVCAHGQCCEECRLKPAGTLCRESSNSCDLPEFCTGANPYCPANV
YLHDGHACQSVEGYCYNGICQTHEQQCITLWGPGAKPAPGICFERVNSAGDPYGNCGKDS
KGSFAKCDARDAKCGKIQCQGGANRPVIGTNAVSIETNIPLQEGGRILCRGTHVYLGDDM
PDPGLVLAGTKCGDGTVCLNRQCQNVSVFGVHECSGKCNGRGVCNNKKNCHCEAHRAPPF
CEETGFGGSIDSGPMRLAADSVVITVAILVTLVSLLVTTVVIFLRRKTLLRLLFTNKKST
LEKFSSLVLLKPPENFQPSFMSAEPLLPPHNFHSHSLRRLPVYQPLHISQPMPVSLSVGQ
PTLPPLPALHRGLPAHTSLSPPRIFTHAEPAVLDATGMDFEKPSAPQKPLPADPLGRSSR
RGNSFTAARVHIPGTGPLPVPTPTVPRPPPTIPLPNSTKYII

>Gasterosteus aculeatus_ADAM12b(ENSGACP_3447)
VTSERLLSLFILSRGLFASNYTETHYLQDGNAVTGSHNFTANCYYHGEVEGRVDSDVSLS
TCAGVKGFITLEGKSYVLEPSADHSDETHWIYTAEHLNFASGTCGHDFNISYPTDAAASS
PFRAFSTRHKRHVQTTTKYVELIIVADNREFQKQGKDMEKVKQRLAEIANYVDKFYRALN
IRVALVGLEVWSDVDKCPITQDPFTTLHEFLDWRKVKLLPTKPHDNAQLISGVYFQGTTI
GMAPIMSMCTAEQSGGIVMDHSDNPIGAAVTLAHELGHNFGMNHDTPERGCGCRVTVDRG
GCIMTPSTGYPFPTVFSSCSKKDLTASFEKGVGMCLFNMPEVKVLYGGQKCGNGYVEEGE
ECDCGELEECMNPCCNASTCTLKGDAVCAHGQCCQDCQLKPAGTPCRESSNSCDLPEFCT
GSSPHCPSNVYLHDGHACHNVDGYCYNGVCQTHEQQCITLWGQGAKPAPGVCFQRVNSAG
DPYGNCGKDSRGSFAKCEARDAKCGKIQCQGGANRPVIGTNAVSIETNIPMQEGKRILCR
GTHVYLGDDMPDPGLVLTGTKCGDGLMCLNRQCQNVSVFGVHACAAKCSSRGVCNNNKNC
HCEAHWAPPFCDKAGLGGSVDSGPIRLANSGNLTAGVVVALLAVLGAGLIIAIKRKALVD
LLFTSKKDPIEKLRSVSAAISSRSATNPPQSLSASPSRPAPPLPPSAAIFKPHHRGGPEA
ALPPAPYPSHSLRRLPKCPPVHLSHPVPLSLTLSLSPGPGLARPPLPPPHAHVAPRGAAF
RGASRHNSCRMVMELEKPSPPQKPLPADPRISRLVRSPSAVQRPSPVCGPAPPGPKQPPT
LPKPCIIANVK

>Oryzias latipes_ADAM12a(ENSORLP_7213)
GLFASHYIETHYMEDGSAVSSAHNYTVDLDKNCYYHGEVQAHPDSDVTLSVCSGLRGLIA
VENKTFVIEPVSGHADGAHIIYHVEELKLAPGACGHSFNGSSAAPQTHINQPIQAFHKRD
KRNTQKTTKYVELIIVADNREFQKQGRDLEKVKQRLAEIANYVDKFYRALNIRVALVGLE
VWSDSDKCPVSQDPFNTLHEFLDWRKVKLLPQRPHDNAQLISGVYFQGTTIGMAPIMSMC
TVEQSGGIVMDHSDNPLGAAVTLAHELGHNFGMNHDTPERGCGCRMTVDRGGCIMTPSTG
YPFPKVFSTCSKKDLAASLEKGVGMCLYNMPEVKVLYGGQKCGNGYVEEGEECDCGEPEE
CMNPCCNATTCTLKGDAVCAHGQCCDDCKLKPAGTLCRESSNSCDLPEFCTGANPHCPAN
VYLHDGHACHNVEGYCYNGICQTHEQQCITLWGTGAKPAPGICFERVNSAGDPYGNCGKD
SKGSFAKCDARDAKCGKIQCQDGANRPVIGTNAVSIETNIPLQEGGRILCRGTHVYLGDD
MPDPGLVLAGTKCGDGMVCLNRQCQNVSVFGVHECSGKCNGRGVCNNKQNCHCEAHWAPP
FCEKAGFGGSIDSGPMRLTGSLNDLTSIFTHADRDTTLLTKQHKALPAVSLTLI

>Oryzias latipes_ADAM12b(ENSORLP_12318)
RGLFASNYTETHYLEDGSAVTGTSNFTAHCYYHGEVQGHDNSDVSLSTCAGIKGFISLGD
RSYVLEPHADRFDGTHRIYTAEHLNFVPGSCGHHFNISSPTIQSSSSSFKAFRSRLKRDV
QTTTKYVELIIVADNREFQKQGKDMEKVKQRLAEIANYVDKFYRALNIRVALVGLEVWSD
VDKCPITQDPFTTLHEFLDWRKVKLLPLKPHDNAQLISGVFFQGTTIGMAPIMSMCTAEQ
SGGIVMDHSDNPLGAAVTLAHELGHNFGMNHDTPERGCGCRVTVDRGGCIMTPSTGYPFP
TVFSSCSKKDLTASFEKGVGMCLYNMPEVKVLYGGQKCGNGYVEEGEECDCGEVEECLNP
CCNASTCTLKGDAVCAHGQCCQDCQLKPAGTPCRESSNSCDLPEFCTGSSPHCPSNVYLH
DGHACHSVEGYCYNGICQTHEQQCITLWGQGAKPAPSICFERVNSAGDPYGNCGKDSKGS
FAKCEQRDAKCGKIQCQGGANRPVIGTNAVSIETNIPLHEGGRILCRGTHVYLGDDMPDP
GLVLTGTKCGDGMMCLNRQCQNVSVFGVHECAAKCSSRGVCNNNKNCHCEAHWAPPFCDK
AGFGGSLDSGPIRVADSRNVTVSVLVVLLTLLGAALIVSIKRKTLLGLLLFSKRKPIEKL
SQAFRPTPNGNAAQVHTSPFSTRLKSPHRGPEVGPSSTSYPSYSLHRLPQCPPVHLNHPI
PLSLTLSLSSGLRQPRPPLPPPHRAPQPHVQAPRGASFRSVAHQNSSRMVVDLEKPSPPQ
KPLPADPRSSRLVQSPSAGQGNRGSSFSASLPGASKPARPAPHPNRPSPKHPPIRP

>Homo sapiens_ADAM15(ENST_356955)
MRLALLWALGLLGAGSPLPSWPLPNIGGTEEQQAESEKAPREPLEPQVLQDDLPISLKKV
LQTSLPEPLRIKLELDGDSHILELLQNRELVPGRPTLVWYQPDGTRVVSEGHTLENCCYQ
GRVRGYAGSWVSICTCSGLRGLVVLTPERSYTLEQGPGDLQGPPIISRIQDLHLPGHTCA
LSWRESVHTQKPPEHPLGQRHIRRRRDVVTETKTVELVIVADHSEAQKYRDFQHLLNRTL
EVALLLDTFFRPLNVRVALVGLEAWTQRDLVEISPNPAVTLENFLHWRRAHLLPRLPHDS
AQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMDHSTSILGVASSIAHELGHSLGLDHDL
PGNSCPCPGPAPAKTCIMEASTDFLPGLNFSNCSRRALEKALLDGMGSCLFERLPSLPPM
AAFCGNMFVEPGEQCDCGFLDDCVDPCCDSLTCQLRPGAQCASDGPCCQNCQLRPSGWQC
RPTRGDCDLPEFCPGDSSQCPPDVSLGDGEPCAGGQAVCMHGRCASYAQQCQSLWGPGAQ
PAAPLCLQTANTRGNAFGSCGRNPSGSYVSCTPRDAICGQLQCQTGRTQPLLGSIRDLLW
ETIDVNGTELNCSWVHLDLGSDVAQPLLTLPGTACGPGLVCIDHRCQRVDLLGAQECRSK
CHGHGVCDSNRHCYCEEGWAPPDCTTQLKATSSLTTGLLLSLLVLLVLVMLGASYWYRAR
LHQRLCQLKGPTCQYRAAQSGPSERPGPPQRALLARGTKQASALSFPAPPSRPLPPDPVS
KRLQAELADRPNPPTRPLPADPVVRSPKSQGPAKPPPPRKPLPADPQGRCPSGDLPGPGA
GIPPLVVPSRPAPPPPTVSSLYL

>Pan troglodytes_ADAM15(ENSPTRP_40612)
MRLALLWALGLLGAGSPLPSWPLPNIGGTEEQQAESEKAPREPLEPQVLQDDLPISLKKV
LQTSLPEPLRIKLELDGDSHILELLQNRELVPGRPTLVWYQPDGTRVVSEGHTLENCCYQ
GRVRGYAGSWVSVCTCSGLRGLVVLTPERSYTLEQGPGDLQGPPIISRIQDLHLPGHTCA
LSWRESVHTQTPPEHPLGQRHIRRRRDVVTETKTVELVIVADHSEAQKYQDFQHLLNRTL
EVALLLDTFFQPLNVRVALVGLEAWTQRDLVEISPNPAVTLENFLHWRRAHLLPRLPHDS
AQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMDHSTSILGVASSIAHELGHSLGLDHDL
PGNSCPCPGPAPAKTCIMEASTDFLPGLNFSNCSRRALEKALLDGMGSCLFERLPSLPTM
AAFCGNMFVEPGEQCDCGFLDDCIDPCCDSSTCQLRPGAQCASDGPCCQNCQLRPSGWQC
RPTRGDCDLPEFCPGDSSQCPPDVSLGDGEPCAGGQAVCMHGRCASYAQQCQSLWGPGAQ
PAAPLCLQTANTRGNAFGSCGRNPSGSYVSCTPRDAICGQLQCQTGRTQPLLGSIQDLLW
ETIDVNGTELNCSWVHLDLGSDVAQPLLTLPGTACGPGLVCIDHRCQRVDLLGAQECRSK
CHGHGVCDSNRHCYCEEGWAPPDCTTQLKATSSLTTGLLLSLLVLLVLVMLGASYWYRAR
LHQRLCQLKGPTCQYRAAQSGPPERPGPPQRALLAQGTKQASALSFPAPPSRPLPPDPVS
KRLQAELADRPNPPTRPLPADPVVRSPKSQGPAKPPPPRKPLPADPQGRCPSGDLPGPGA
GIPPLVVPSRPAPPPPTVSSLYL

>Mus musculus_ADAM15(ENSMUSP_29676)
MRLALLWALGLLGAGSPRPSPPLPNIGGTEEEQQASPERTLSGSMESRVVQDSPPMSLAD
VLQTGLPEALRISLELDSESHVLELLQNRDLIPGRPTLVWYQPDGTRMVSEGYSLENCCY
RGRVQGHPSSWVSLCACSGIRGLIVLSPERGYTLELGPGDLQRPVISRIQDHLLLGHTCA
PSWHASVPTRAGPDLLLEQHHAHRLKRDVVTETKIVELVIVADNSEVRKYPDFQQLLNRT
LEAALLLDTFFQPLNVRVALVGLEAWTQHNLIEMSSNPAVLLDNFLRWRRTDLLPRLPHD
SAQLVTVTSFSGPMVGMAIQNSICSPDFSGGVNMDHSTSILGVASSIAHELGHSLGLDHD
SPGHSCPCPGPAPAKSCIMEASTDFLPGLNFSNCSRQALEKALLEGMGSCLFERQPSLAP
MSSLCGNMFVDPGEQCDCGFPDECTDPCCDHFTCQLRPGAQCASDGPCCQNCKLHPAGWL
CRPPTDDCDLPEFCPGDSSQCPSDIRLGDGEPCASGEAVCMHGRCASYARQCQSLWGPGA
QPAAPLCLQTANTRGNAFGSCGRSPGGSYMPCAPRDVMCGQLQCQWGRSQPLLGSVQDRL
SEVLEANGTQLNCSWVDLDLGNDVAQPLLALPGTACGPGLVCIGHRCQPVDLLGAQECRR
KCHGHGVCDSSGHCRCEEGWAPPDCMTQLKATSSLTTGLLLSLLLLLVLVLLGASYWHRA
RLHQRLCQLKGSSCQYRAPQSCPPERPGPPQRAQQMTGTKQASVVSFPVPPSRPLPPNPV
PKKLQAALADRSNPPTRPLPADPVVRRPKSQGPTKPPPPRKPLPANPQGQHPPGDLPGPG
DGSLPLVVPSRPAPPPPAASSLYL

>Rattus norvegicus_ADAM15(ENSRNOP_39351)
MRLALLWALGLLGAGSPRPSPPLPNIGGTEEEQQASPERTQSRSLENQVVQDSPPINLTE
VLQTGLPETLRIGLELDGENHILELQQNRDLVPGRPTLVWYQPDGTRMVSEGHSLENCCY
RGRVQGRPSSWVSLCACSGIRGLVVLSPERSYTLELGPGDLQRPLIVSRIQDLLLPGHTC
APSWHAFVPTEAAPDLLLEQHHLRRLKRDVVTETKIVELVIVADNSEVRKYPDFQQLLNR
TLEVALLLDTFFQPLNVRVALVGLEAWTQRDLIEMSSNPAVLLDNFLRWRRTDLLPRLPH
DSAQLVTVTSFSGPMVGMAIQNSICSPDFSGGVNMDHSTSILGVASSIAHELGHSLGLDH
DSPGNSCPCPGPAPAKSCIMEASTDFLPGLNFSNCSRWALEKALLDGMGSCLFEWPPSRA
PMSSLCGNMFVDPGEQCDCGFPDECTDPCCDYFTCQLRPGAQCASDGPCCQNCKLQPAGW
QCRLPTDDCDLPEFCLGDSSQCPPDIRLGDGEPCASGEAVCMHGRCASYTRQCQSLWGPG
AQPAAPLCLQTANTRGNAFGSCGRSPSGSYMPCNLRDAICGQLQCQWGRNQPLLGSVQDQ
LSEVLEANGTQLNCSWVDLDLGNDVAQPLLALPGTACGPGLVCIGHRCQPVDLLGAQECR
SKCHGHGVCDSSRHCHCDEGWAPPDCMTQLRATSSLTTGLLLSLLLLLVLVLLGASYWYR
ARLHQRLCQLKGSSCQYRAAQSGPPERPGPPQRAQQMPGTKQANVSFPVPPSRPLPPNPV
PKKLQAELADRSNPPTRPLPADPVVWRPKPQGPTKPPPPRKPLPANPQGRPPLGDLPGPG
DGSLQLVVPSRPAPPPPAASSLYL

>Canis familiaris_ADAM15(ENSCAFP_25193)
MRLALLWALGLLGAGSPLTSRPLADIGGTEDEHARPERALGGPSEPQILRDHPMLSLAEM
LQTNLPEAFRIKLELDGDSHILELLQNRDQVPGRPWLMRYQPDGIRVVSEGHTLENCCYQ
GRVQGHASSWVSVCTCSGLRGLVILSPERSYMLDLGPGDLQAPPNISRIQDLFLPGHTCA
LSRHASGPTQAPLEQPPGQHHSCTRRRRDVVAETKIIELVIVADHSETQRYPDSQQLLNR
MLKVTFLLDTFFRPLNVRVVLVGLEAWTQHDLVEISQDPGLTLDNFLHWRRVDLLPRLPH
DSAQLVTATSFSGPTVGMAVQNSICSPDFSGGVNMDHSTSVLGVASSIAHELGHSLGLDH
DLPGNSCPCPGPAPAKSCIMEASTDFLPGLNFSNCSRQALEKALLDGMGSCLFERLPSLP
SMATVCGNMFVEPGEQCDCGFPDDCTDPCCDYFTCQLRPGAQCASNGLCCQNCQLRPAGW
QCRPARGDCDLPEFCPGDSSHCPPDVSLGDGEPCAGGQAVCVQGRCASYAQQCQALWGPG
AQPTAPLCLIAANTRGDAFGSCGRSPNGSYMSCAPKDAMCGQLQCQGGQAQPLLGSARDL
HWEVLEANGTQPRLNCSWVHLDLGDDVAQPLLALPGTACGPDLVCIDHQCQPVDVLRAQE
CRSKCHGHGVCDSKGHCHCEEGWAPPDCTSHVRATSSLTTGLPLSLLLVVVLVLLGASYW
HRARLRQRLCQLKGPSCQYRAAQSGPSECPGPPQRVLLMPGAKQAGILGFPAPPSRPLPP
DPVPKRLQAELADRPNPPTRPLPADPMVRHPKGPAKPPPPRKPLPANPQGRGPSGDLPGP
GAGIPPLVVPSRPAPPPPAASSSLYL

>Bos taurus_ADAM15(ENSBTAP_14101)
MRLALLWALGLLGAGSPLPSRPLPDIGVTEEMQARPERAQNGPLEPQILQDNPTFSLAEA
LQTSLPEALRIKLELDGESHILELLQNRELVSGRPTLVWYQPDGTRVVGEGHTLENCCYE
GRVRGHAHSWVSLCTCSGLRGLVILSPERSYSVELGPGDLQGPPVVSRIQDLLLPRHTCA
LSWPTSVLPQALPEPSLGQRHTHRWRRDVVTETKIVELVIVADHAEVKRHRDFQSLLNRT
LEVALLLDTFFRPMNVRVALVGLEAWTQHNLIEISQNPGLTLDSFLHWRRTNLLPRLPHD
SAQLVTATSFSGPMVGMAIQNSICSPEFSGGVNMDHSTSILGVASSIAHELGHSLGLGHD
SPGNSCPCPGPAPAKSCIMQASTDFLPGLNFSNCSRQALEEALLGGMGSCLFERLSGLPS
MASVCGNMLVEPGEQCDCGFPDECTDPCCDYFTCQLRPGAQCASDGLCCHNCQLRPAGWK
CRPTRGDCDLPEFCPGDSSQCPPDVSMGDGEPCASGQAVCMQGRCASYAQQCQALWGPGA
KPAAPLCLLTANTRGDAFGSCGRNPDGSYVSCAPRDAMCGQLQCQGGRAQPLLGSARDLR
WEMLEANGTQLRLNCSWVHLDLGNDVAQPLLTLPGTACGPGLVCVEQQCQPIEVLGAQEC
QRRCHGHGVCDSNRRCHCEEGWAPPDCTTHVRATSSLTTGLPLSLLLLLVLVLLGASYWH
RARLHQRLCQLKGPSCQYRLRAAQSGPPERPGPPQRALVMPGAKQASALGFPAPPSRPLP
PDPVPKRLQAELADRPNPPTRPLPADPVVRRPKSQGPTKPPPPRKPLPADPHGRRPSGDL
PGPGAGIPPPVVPSRPAPPPPAASSPYL

>Monodelphis domestica_ADAM15(ENSMODP_21366)
MRLALLWALGLLGAGSPMPSRTLLDTGQMGEQLPLPEELPRRYPEPQILQGNLTLNLSEA
LQDSVPEKLLIKLELDGKSHILELQQNGELVPDTPTLVWYQSDGSRVVNEGDTLENCCYQ
GTVQDHPDSWASVCICSGLRGLVVLSPEKVYTLDPGPWGGTHISKIEDVHPKGGTCALKP
GPHVLTQAQSELKLDLHHLYRSKRDVVSETKFVELVIVADHQEAQRYPDLHQLQTRMLEV
ANQVDAFFRPLNVRVALVGVEVWSQKDMIAMDRDAGITLDRFLRWRQAELLPQLPHDSAQ
LVTTNLFLNSSVGMAVQGSICSPSLSGGVNVDHSVSILGVASTMAHELGHSLGLAHDPPG
GNCPCPGQPPAKSCIMEAATAFLPGLSFSTCSKEALEKALLRGAGSCLFSRPPQLAPRPP
RCGNLFVEPGEQCDCGFWEECSDPCCNASSCQLMPGAHCASDGFCCQACQFRPVGWLCRP
ARGDCDLPEFCSGDSGQCPSDVSLGDGEPCAGGKAVCAAGHCASYVAQCQALWGPGARPA
TPFCLQAANTRGDSFGNCGKQNNGSYVPCAPRDASCGQLQCQGGGAHPLLGTAQDTLTET
VEVNGTRQTCRWTHLDLGSDVAQPFLALMGTTCAPGQVCIDQRCQPSVLLGAEECRNKCH
GHGVCNSNGHCHCDQGWAPPDCSNQGFGGTSGGLTAALLLSLLLLALLMLLGACYWHRTH
LRRRLCQFKGTSSQYRTSPHGPPERPGPPQRTQATELHLMPSTKSGALGHPDPPSRPLPP
DPVPKRIQAALTDRPNPPTRPLPADPVVRSPQVQGPVKPPPPRKPLPSYPQGPSEDSSVS
LGMPSPSRPAPPPPTASGAAL

>Danio rerio_ADAM15(ENSDARP_105508)
MKQHHHQLFRCFWRTLVTILLFEGTPLMMFRGSLTLTLHRNDSSFTPQPDARITHSSHNV
TNHRREQKPLAMTRPFAFVDGVRRSLSDVLQKGHPDRLQCGLQVGSSLYILDLEKNQDLL
PKPPNVFYYLPNGTGVSMKENTVTHCYYHGSVQGFPESRVALSSCSGLRGVIVINATLSF
ELLPEGEEERGKDDEGSGEMEEGEMHAIYSTHSPTSESRDCGVSHTSIPPIQIIPHTHRS
KRDILSEIKYIELVLVADHKEYLNYQKNNKTIIYRMLDVANQVDWFYRPLNVRVALLGLE
IWSDQDKIKVDKSPTETLNRFLDWRTRELLPRLRHDNAQLIMGESFDGTTVGMASQSSMC
SKDRSGGVNVDHLVSVLGVASTVAHELGHNLGMSHDTADRRCHCQNEPRLGGCIMEPSTG
FMPGQLFSSCSERDLSLSLLHGGGMCLFNVPQPESLLGGPRCGNLYVEKGEECDCGLLDE
CNDPCCNASTCKLVPGAQCSSDGICCENCKLRVAGSVCREPLGECDLPEHCTGSSPYCPP
NVFLQNGEPCKGGSSYCYSGVCASLDDQCQMLWGQNSTRAPPICFSSVNKQGNKYGNCGQ
MPNGSYIPCLKWDVHCGRIQCQGGGERPLLGSNAEILTTTVILNQSDFTCRGTYFNLGDD
VSDPAMVLQGTACGPNKACVDQKCRDVSMFGVDECRSKCHGHGVCNSNKNCHCDEGWAPP
DCRYSGNGGSVDSGPAQEPRDSDPARVALLVIFLFVLPVSLLFVALRFPRCRRGLVYLGH
TPFNKTRQSRTPAMELANARNGDQAQPLRYQWPHQSDIPLTQAISKVQNRPAAPTKPLPP
DPPVSKPAQLAAHWPAPPTKPLPPDPAPSESKMQCKPTGARPAAPSKPLPPDPVLSSRQN
PVPPKPPVPKKPLPVDPSCHPPVPPLMGHPVSAAASSSSYSSRNSASAAAPARPAPHPPL
RRQQYHGKPHSSHPV

>Takifugu rubripes_ADAM15(ENSTRUP_24130)
HPDRLQCGLEVSGRLFILNLEKNRDLLPNPPNIFYYLPNGTGVSVRAGPVTHCYYHGSVL
GFPESRVAVSTCSGLRGVVTINSSLAFEVQPLEDYNHPQEDVGDTSEGNGARSCGVSHAA
VPPIHSSSHMRRSKRDILSETKYIELVLVADHQEFLNFQRNNKTIIYRLLDVANQVDWYY
RPLNVRVALTGMEIWSDQDKISVEKNPTSTLNNFLEWRTRDLLPRFRHDNAQLIMGGSFD
GTTVGMASQSSMCSRDRSGGVSVDHLVSVLGVASTIAHELGHNLGMSHDTAERRCACQNE
PRLGGCIMEPSTGFLPGQQFSSCSAADLSVSLLHGGGMCLFNMPRPERLLGGPRCGNLYV
EKGEQCDCGLIQDCKDPCCNASTCQLVPGAQCSSDGICCHNCKLRLAGSVCRQPLGECDL
PEFCTGTSPHCPPNVFLQNGEPCQSSTSFCHGGVCANMNTQCQMLWGPNATSAPDVCFSS
VNKQGNKYGNCGQLTNGSYIPCAAADVHCGRIQCRGGRERPLLGTNAEILTTTFNHTSLV
CRGTFFHLADDVSDPATVAQGTTCGPGKACLDQKCTDVSVFGVDDCRSKCHHHGVCNSNR
NCHCDVGWAPPDCRSSGLGGSVDSGPATGAAGVCVCVCVCVCVLCLVWALRLIQFKIVQL
LTTIKHLLTTIKHLLTVGPSPSSSARHLLPGPSSRPVLPRPSAPSSPTAARLHHSQQSDA
QKQTTQPVTHTLHQVHQRPAPPTKPLPPDPALTPPPQVKQHPAPPTKPLPPDPCAQLSQP
SQPRPVVPIKPCQLPPLSHPHVPPGPSHPTTKPSLQAVAS

>Tetraodon nigroviridis_ADAM15(ENSTNIP_8935)
LQEGHPDRLQCGLEVSGRLFLLNLEKNHDLLPKPPNIFYYLPNGTGVSARADSVTHCYYH
GSVQGFPESRVALSTCSGLRGVVTVNSTLTIELQPAGGGAAGADLHLVFSTSPSEDSGTR
SCGLSRAAVPPIHSSSHTRRSKRDILTETKYIELVLVADHQEFLNYQQNNRTLVYRLLDV
ANQVDWFYRPLNVRVALTGLEIWSERDQISVEKNPSSTLNNFLEWRSRDLLPRFRHDNAQ
LIMGGSFDGTTVGMASQSSMCSTDRSGGVSVDHLVSVLGVASTVAHELGHNLGMSHDTAE
RRCSCQKEARQGGCIMEASTGFLPGQQFSSCSAADLSVSLLHGGGMCLFNTPAPERLLGG
PRCGNLYVEKGEQCDCGLVEDCEDPCCNASTCQLLPGAQCSSQGICCHQCKFRVAGSVCR
APLGECDLPEFCTGSSPHCPANVFLQNGALCRGGASYCFGGVCADMDSQCQMLWGPNATS
APAVCFSSVNKQGNKHGNCGQLTNGSYLPCAAADVQCGRIQCRGGRERPLLGTSAEILTT
TFNHSSLVCRGTFYHLADDVSDPATVAQGTACGPGKACLDQKCTDASVFGVDDCRSKCNH
HGVCNSNRNCHCEPGWAPPDCRYSGLGGSVDSGPATSRAGECVCVWVPRPPSLLGQSRRA
GPQKQAEPVTPQHQPGSKQMAGTENRQVHERPAPPTKPLPPDPAPTPPAQLLVTRPAPPT
KPLPPDPVKPAQPPAPTGPSPPPAGTQLPPHPQASPPGRRPRQASGSPELKAALAAAPFP
PLSAGVMI

>Gasterosteus aculeatus_ADAM15(ENSGACP_1138)
HPDRLQCGLEVGGRLFLLDLEKNHDLLPKPPNVFYYLPDGTGVSVRADPVTHCYYHGNIR
GFPHSRVALSTCSGLRGLIAFNSTLSFELQPQEDLHLHQLLFSTSPREGDATGGCGVSHT
AVPPLHSSTHTHRRKRDILSETKYIELVLVADHQEYLNYQKNNKTLIYRMLDVANQVDWF
YRPLSVRVALTGLEIWSDRDKIQVEKSPTDTLNNFLEWRTRELLPRLRHDNAQLVMGESF
DGTTVGMASQASMCSRDRSGGVNVDHLVSVLGVAATVAHELGHNLGMSHDTAERRCSCQN
EQRLGGCIMEPSTGFMPGQQFSSCSAADLSVSLLHGGGMCLFNVPQPDRLLGGPRCGNLY
VETGEQCDCGLLEECEDPCCNASTCQLVSGAQCSSDGICCQDCKLRAAGSVCRDPLGECD
LPEFCTGSSPYCPPNVFLQNGEPCEDDASYCYEGVCASMLTQCRMLWGPNATTAPPVCFS
SVNKQGNKYGNCGQLSNGSYLPCGNSDTHCGRIQCRGGRERPLLGTNAEILTTTVRFNHS
DLVCRGTFFHLGDDVSDPATVAQGTACGPGKACLNQKCQDVSVFQVEECRGKCNGHGLLH
NNKMCHCEAGRAPPDCRYSGHGGSVDSGPARAAGGTSAAPLSDAQRPPTQPVGTQVTSSP
MSLRLF

>Oryzias latipes_ADAM15(ENSORLP_21130)
LFQDGHPDMLQGALEVGGRVLLLDLQKNHRLLPKPPNVFLYLPNGTGVSVPADPVTHCYY
HGNVRGFPQSRVAVSTCSGLRGVIALNSSLSFEVEPQDLRLQGDKDALKRKAALTPNVIY
AARASSFNVKSLCRTIRGPAARFERLTKRDILTETKYIELVLVADHQEFLNYQKNNKTII
YRMLDVANQVDWFYRPLNVRVALTGLEIWSDRDKIRVEKSATDTLNNFLDWRTRDLLPRL
RHDNAQLVMGESFDGTTVGMASQSSMCSRDRSGGVNVDHLVSVLGVASTIAHELGHNLGM
RHDTAERRCSCQNEPRLGGCIMEPSTGFLPGQQFSSCSITDLTLSLQHGGGMCLFNVPQP
DQLLGGPRCGNLYVEKGEECDCGLLQECEDPCCNASTCQLVPGAQCSSDGICCQNCKLRP
AGSMCRGPLGDCDLPEFCTGSSPHCPPNVFLQNGEVCENSTSYCYEGVCANMDTQCQMLW
GPNATSAPAVCFSSVNKQGNKYGNCGQLANGSYIPCGNADVHCGRIQCQGGRERPLLGSN
AQILTTTVRFNDSDLTCRGTFFHLGDDVSDPATVAQGTACGPGKACLNHKCREVSMFGVD
ECRRKCNGHGVCNSNKNCHCDVGWAPPDCRYSGSDPVRVALLVIFFFILPVVLLFLALRY
PRFRRALCCLGPSSPFHKARQHNRLINSPPACLTPLLPVLYQANDRPAPPNKPLPPDPAL
TPPSKSVMEAEGCSRPSQVSVPLKPVVPPKPRLPAPPTNPQLPAHPGLPPHLGYASHGAV
APAPGPSRRPPLRPSRPPAPPKAESPV

>Homo sapiens_ADAM19(ENST_517905)
MPGGAGAARLCLLAFALQPLRPRAAREPGWTRGSEEGSPKLQHELIIPQWKTSESPVREK
HPLKAELRVMAEGRELILDLEKNEQLFAPSYTETHYTSSGNPQTTTRKLEDHCFYHGTVR
ETELSSVTLSTCRGIRGLITVSSNLSYVIEPLPDSKGQHLIYRSEHLKPPPGNCGFEHSK
PTTRDWALQFTQQTKKRPRRMKREDLNSMKYVELYLVADYLEFQKNRRDQDATKHKLIEI
ANYVDKFYRSLNIRIALVGLEVWTHGNMCEVSENPYSTLWSFLSWRRKLLAQKYHDNAQL
ITGMSFHGTTIGLAPLMAMCSVYQSGGVNMDHSENAIGVAATMAHEMGHNFGMTHDSADC
CSASAADGGCIMAAATGHPFPKVFNGCNRRELDRYLQSGGGMCLSNMPDTRMLYGGRRCG
NGYLEDGEECDCGEEEECNNPCCNASNCTLRPGAECAHGSCCHQCKLLAPGTLCREQARQ
CDLPEFCTGKSPHCPTNFYQMDGTPCEGGQAYCYNGMCLTYQEQCQQLWGPGARPAPDLC
FEKVNVAGDTFGNCGKDMNGEHRKCNMRDAKCGKIQCQSSEARPLESNAVPIDTTIIMNG
RQIQCRGTHVYRGPEEEGDMLDPGLVMTGTKCGYNHICFEGQCRNTSFFETEGCGKKCNG
HGVCNNNQNCHCLPGWAPPFCNTPGHGGSIDSGPMPPESVGPVVAGVLVAILVLAVLMLM
YYCCRQNNKLGQLKPSALPSKLRQQFSCPFRVSQNSGTGHANPTFKLQTPQGKRKVINTP
EILRKPSQPPPRPPPDYLRGGSPPAPLPAHLSRAARNSPGPGSQIERTESSRRPPPSRPI
PPAPNCIVSQDFSRPRPPQKALPANPVPGRRSLPRPGGASPLRPPGAGPQQSRPLAALAP
KVSPREALKVKAGTRGLQGGRCRVEKTKQFMLLVVWTELPEQKPRAKHSCFLVPA

>Pan troglodytes_ADAM19(ENSPTRP_29845)
MPGGAGAARLCLLAFALQLLRPRAAREPGWTRGSEEGSPKLQHELIIPQWKTSESPVREK
HPLKAELRVMAEGRELILDLEKNEQLFAPSYTETHYTSSGNPQTTTRKSEDHCFYHGTVR
ETELSSVTLSTCRGIRGLITVSSNLSYVIEPLPDSKGQHLIYRSEHLKPPPGNCGFEHSK
PTTRDWALQFTQQTKKRPRRMKREDLNSMKYVELYLVADYLEFQKNRRDQDATKHKLIEI
ANYVDKFYRSLNIRIALVGLEVWTHGNMCEVSENPYSTLWSFLSWRRKLLAQKYHDNAQL
ITGMSFHGTTIGLAPLMAMCSVYQSGGVNMDHSENAIGVAATMAHEMGHNFGMTHDSADC
CSASAADGGCIMAAATGHPFPKVFNGCNRRELDRYLQSGGGMCLSNMPDTRMLYGGRRCG
NGYLEDGEECDCGEEEECNNPCCNASNCTLRPGAECAHGSCCHQCKLLAPGTLCREQARQ
CDLPEFCTGKSPHCPTNFYQMDGTPCEGGQAYCYNGMCLTYQEQCQQLWGPGARPAPDLC
FEKVNVAGDTFGNCGKDMNGEHRKCNMRDAKCGKIQCQSSEARPLESNAVPIDTTIIMNG
RQIQCRGTHVYRGPEEEGDMLDPGLVMTGTKCGYNHICFEGQCRNTSFFETEGCGKKCNG
HGVCNNNQNCHCLPGWAPPFCNTPGHGGSIDSGPMPPESVGPVVAGVLVAILVLAVLTLM
YYCCRQNNKLGQLKPSALPSKLRQQFSCPFRVSQNSGTGHANPTFKLQTPQGKRKVINTP
EILRKPSQPPPRPPPDYLRGGSPPAPLPAHLSRAARNSPGPGSQIERTELSRRPPPSRPI
PPAPNCIVSQDFSRPRPPQKALPANPVPGRRSLPRPGGASPLRPPGAGPQQSRPLAALAP
KFPEYRSQRAGGMISSKI

>Mus musculus_ADAM19(ENSMUSP_11400)
MPGRAGVARFCLLALALQLHWPLAACEPGWTTRGSQEGSPPLQHELIIPQWRTSESPGRG
KHPLRAELRVMAEGRELILDLEKNEHLFAPAYTETCYTASGNPQTSTLKSEDHCFYHGTV
RDVDESSVTLSTCRGIRGLIIVRSNLSYIIEPVPNSDSQHRIYRSEHLTLPPGNCGFEHS
GPTSKDWALQFTHQTKKQPRRMKREDLHSMKYVELYLVADYAEFQKNRHDQDATKRKLME
IANYVDKFYRSLNIRIALVGLEVWTHGDKCEVSENPYSTLWSFLSWRRKLLAQKSHDNAQ
LITGRSFQGTTIGLAPLMAMCSVYQSGGVSMDHSENAIGVASTVAHEIGHNFGMSHDSAH
CCSASAADGGCIMAAATGHPFPKVFSWCNRKELDRYLQTGGGMCLSNMPDTRTLYGGRRC
GNGYLEDGEECDCGEEEECKNPCCNASNCTLKEGAECAHGSCCHQCKLVAPGTQCREQVR
QCDLPEFCTGKSPHCPTNYYQMDGTPCEGGQAYCYNGMCLTYQEQCQQLWGPGARPALDL
CFERVNAAGDTYGNCGKGLNGQYRKCSPRDAKCGKIQCQSTQARPLESNAVSIDTTITLN
GRRIHCRGTHVYRGPEEEEGEGDMLDPGLVMTGTKCGHNHICFEGQCRNTSFFETEGCGK
KCNGHGVCNNNKNCHCFPGWSPPFCNTPGDGGSVDSGPLPPKSVGPVIAGVFSALFVLAV
LVLLCHCYRQSHKLGKPSALPFKLRHQFSCPFRVSQSGGTGHANPTFKLQTPQGKRKVTN
TPESLRKPSHPPPRPPPDYLRVESPPAPLPAHLNRAAGSSPEAGARIERKESARRPPPSR
PMPPAPNCLLSQDFSRPRPPQKALPANPVPGQRTGPRSGGTSLLQPPTSGPQPPRPPAVP
VPKLPEYRSQRVGAIISSKI

>Rattus norvegicus_ADAM19(ENSRNOP_8184)
MPGRAGVARFCLLALALQLQWPLAACEPEWTTRGSKEDSPPLQHELIIPQWRTSESPRGG
KHPLTAELRVMAEGRELILDLEKNEHLFAPAYTETCYTASGNPQTTTLKSEDHCFYHGTV
RKVDESSVTLSTCRGIRGLIIVRSNLSYIIEPVPNSDNQHRIYRSEHLKLPPGNCGFEHS
RPTSKDWTLQFTHQTKKQPRRMKREDLHSMKYVELYLVADYAEFQKNRHDQDATKHKLME
IANYVDKFYRSLSIRIALVGLEVWTHGDKCEVSENPYSTLWSFLSWRRKLLTQKSHDNAQ
LITGRSFQGTTIGLAPLMAMCSVYQSGGVSMDHSENAIGVASTVAHEIGHNFGMSHDSAH
CCSTSAADGGCIMAAATGHPFPKVFSSCNRKELDRYLQSGGGMCLSNMPDTRTLYGGRRC
GNGYLEDGEECDCGEEDECKNPCCNASNCTLKEGAECAHGSCCHQCKLVAPGTQCREQVR
QCDLPEFCTGKSPHCPTNYYQMDGTPCEGGQAYCYNGMCLTYQEQCQQLWGPGARPALDL
CFERVNAAGDTYGNCGKGLNGKYRKCSPRDAKCGKIQCQSTQARPLESNAVSIDTTITLN
GRRIHCRGTHVYRGPEEEEGEGDMLDPGLVMTGTKCGHNHICFEGQCRNTSFFETEGCGK
KCNGHGVCNNNKNCHCFPGWAPPFCNTPGDGGSIDSGPLPPKSAGPVIAGVFSALFVLAV
LVLLCHCYRQSHKLGKPSALPFKLRQQFSCPFRVSQNGGTGHANPTFKLQTPQGKRKVTN
TPETLRKPSHPPPRPPPDYLRVESHPAPLPAHLNRAAGSSPEAGAQIERKESARRPPPSR
PMPPAPNCLLSQDFSRPRPPQKALPANPVPGQRTVPRPGGTSLFHPPTTGPQPPRPPAVS
VPKLPEYRSQRIGGITSSKI

>Canis familiaris_ADAM19(ENSCAFP_25579)
MARGAGAVRLCLLALALPGWTTRGNGEGSPLLQHERIIPQWKTAESPTKEKHPLKAELRI
TAEGQELILDLEKNEHLFAPAYTETHYTPHGNPQTTMLKSEEHCFYHGTVRKAEQSSVAL
STCRGMRGLITVSSNLSYIIEPLPDSEGHHLIYRSEHLKLPLGNCGFKYSKSITGDRVLP
SMNQTKKRPRRMKREDLHSMKYVELYLVADYAEFQKNRRDQDATKHKLMEIANYVDKFYR
SLNIRIALVGLEVWTHGNMCEVSENPYSTLWSFLSWRRKLLTQKNHDNAQLITGMSFHGT
TIGLAPLMAMNSVYQSGGVNMDHSENAIGVAATMAHEMGHNFGMSHDSAECCSASAADGG
CIMAAATGHPFPRVFNGCNRKELDRYLQSGGGMCLSNMPDTRTLYGGRRCGNGYLEDGEE
CDCGEEEECNNPCCNASNCTLREGAECAHGACCHQCKLLAPGTLCREQARQCDLPEFCTG
KSPHCPTNFYQMDGTPCEGGQAYCYNGMCLTYQEQCQQLWGPGARPAPDLCFEKVNVAGD
TFGNCGKDMNGEHKKCNMRDAKCGKIQCQSSEARPLESNAVPIDTTIILNGRQIRCRGTH
VYRGPEEEGDMLDPGLVMTGTKCGYNHICFEGQCRNTSFFETEGCGKKCNGHGVCNNNQN
CHCFQGWAPPFCNTPGQGGSIDSGPMPSDSVGPMIAGVFTAVFVLAVLMLIYCCCKQNNK
LGQLKPLALPSKLRQQFSCPFRVSQNSGTGHANPTFKLQTPQGKRKVTNTPETPRKPSQP
PPRPPPDYLHGGSPPAPLPAHLSRAARNSPGAGPQVERRESSRRPPPSRPVPPAPNCILS
QDFSRPRPPQKALPANPVPGRKSLPRPGGTSILQPTATTPLQPRPLAAPVPKFPEYRPQR
AGGMIGSKI

>Bos taurus_ADAM19(ENSBTAP_5003)
MPRGVGIAQLCLLVLALPGWTRRGSGEGSPQLQHELIIPQWKTAESPMREKHPLKAELRV
MAEGRELILDLEKNEHLFAPAYTETCYTPSGDAQTTTLKSEDHCFYHGTVRKAEQSSVML
STCRGMRGLIIVSSNLSYIIEPLPDSESHHRIYRSEHLKLPLGNCGFEPTARDWVPQFTN
QTKKRPRRMKREDLHSMKYVELYLVADYAEFQKNGLDQDATKHKLMEIANYVDKFYRSLN
IRIALVGLEVWTHGNMCEVSENPYSTLWSFLSWRRKLLTRKNHDNAQLITGMSFHGTTIG
LAPLMAMCSVYQSGGVNMDHSENAIGVAATMAHEMGHNFGMSHDSADCCSASAADGGCIM
AAATGHPFPRVFNRCNRRELDRYLQSGGGMCLSNMPDTRTLYGGRRCGNGYLEDGEECDC
GEEEECENPCCNAANCTLREGAECAHGSCCHRCKLLAPGMLCREQARQCDLPEFCTGKSP
QCPTNFYQMDGTPCEDGQAYCYNGMCLTYQEQCQQLWGPGARPAPDLCFEKVNVAGDTFG
NCGKDMNGKHKKCNMRDAKCGKIQCQSSEARPLESNAVPIDTVIVINGRQIRCRGTHVYR
GPEEEGDMLDPGLVMTGTKCGHNHICFEGQCRNTSFFEMEGCAKKCNGHGVCNNNQNCHC
FRGWAPPFCNTPGQGGSIDSGPMPPESAGPVVAGVFSAIFVLVALIMMYRCCKQNNKLGY
LKSLALPSKLRQQFSCPFRVSQNSGTGHANPTFKLQTPQGRRKVTNTPETLRKPSQPPPR
PPPDYLHSVSPPAPSPAHLSKAARNSPGPRPSVERKESSRGPPPSRPVPPAPKCVLSQDL
SRPRPPQKALPANPVPGRKNLPRPSGASILRPPPSGPPQTRPLVAPAPKFPEYRSQRAVG
MTSSKI

>Gallus gallus_ADAM19(ENSGALP_5930)
MRGWGLLCGIALSLLLQPPPCSAEAGSTEPQPAVLVSSWDVLRSPGGEQHPLRAEVRIRA
EGQELILDLEKNGDLFAPGYTETHYSQTGQARTIPLAHTEHCFYQGVVRGREHSSVTLSS
CQGLRGLIVLRSNFSYVLEPLPDSTDQHRIYRLDDLKMPAGACGHQGSMATGRNWLGDFA
AGVKFPNHRVRREALQATKYVELLLVADYAEVQKHHFNIEATRLKLVEAANYVDKFYRSL
NIRIALVGLEIWSNGNKCDCTENPYSTLKSFLAWSSKERVYRKHDNAQLITGVPFQGTTV
GLAPVMSMCSDFQSGGVNMDHSDNAIGVAATIAHEMGHNFGMNHDSSGCCTTRAEEGGCI
MASATGHPFPRVFNQCNRRELEKYLHSGGGMCLSNMPDTKRMYGGRKCGNGYLEEGEECD
CGEVEECNNPCCNANNCSLKLGAECAHGSCCHECKLMSPGTLCREKSGLCDLPEYCTGQS
PFCPSNSYQIDGASCEGGKAYCYNGMCLTYKDQCLQLWGPGAQPAPDTCFENVNAAGDVY
GNCGKDVYGNYRKCEKRDAKCGKIQCQSSASKPVLPNAVPIDTTITLQRTRVRCRGTHVY
RFENEEKEMLDPALVLTGTKCGSHHVCFEGRCQNTSIIFESESCSEKCNGNGVCNNNKNC
HCNPGWAPPFCNKQGRGGSLDSGPPSPEGSSAVVIALAILASILLLIGIVLLFYYLKCWN
KFVICSLKKAPQISDASGNGHANPAFKLRTPQQERKVIGFPEIPSKPPPQPAPSLRINMQ
QQSAFTSYSYGTGSPAGPMHPALAKDVPQRTPPSRPAPPAPRSPSSQDVLRPRPPQRALP
ANPVPNRSRAQPGVSPAIPLPPTRPRIPGQLQPAAENTGVRTAGAVNMLRRGQPGSSAHP

>Danio rerio_ADAM19(ENSDARP_87985)
MLRSVHLNRCTGAGAVHFPQLLLLCCCCLQLFIKCTAHFEEIFRDERWHGDSSHIHDDSE
HYITFPQWISPARHKRSEMVVKHPSEAEVKITVGGEDLILQLQRNEELFSSEYQEIWYDT
NGNRQFSRPSIRDHCYYHGSVKEAEGSSVVISTCAGLRGLITVNNSVSYMIQPLANQTHS
QGHAVFNSRRLKLPAGTCGHHHGDGHHTESLQELIDVMAKPQRTNRERRDVSSSMKYVEL
MVVADHAEFVNHNRDLEKTKAKLLEAANFVDKYYKSLKIRVALIRLEIWNDQDKINVTDN
PYSTLGAFLSWRRKQLPQLPNDNAQLVTGVSFHGTIIGLAPLKAMCSEYQSGGVNSDHSN
SAVGIAATMAHELGHNFGMSHDSPGCCRAQAEDGGCIMAAATGAPFPRVFNSCNQNELKR
YLSSGGGKCLFNPPNTRVMYGGQRCGNGYLEEGEECDCGEVEECSSPCCNAHNCTLKSGA
ECAHGVCCHECKLKSPGVMCRPPSGSCDLPEYCDGKSESCPANFFLMDGSSCASGSAYCY
TGMCLTLEQQCLSLWGKDARPAPDLCFTDVNKAGDAFGNCGQDLMGTYRKCTERNAKCGK
IQCQSSASKPLESNAVAIDTTIRSGQQKILCRGTHVWPHGHAKENQNDTLDPGLVLTGTK
CGDNAICFEGECRDASFLQADECSTKCQGHGLCNNNHNCHCHSGWAPPFCGTSGPGGSLD
SGPVISQSSFYLVLVLLSLSFLLALAVLGVCWCRCKQRFLSTKSPALPKTQTCINVPDTP
EPKSHTTGHANPVFQPKKAPADEQATLRASPTGPPRSRHSIIRPTVKPPPIPAYAPHKHL
ISEPSQPSPSVNPKTRPLPPNRPPPPCPTT

>Takifugu rubripes_ADAM19(ENSTRUP_24765)
QLLVPGYQEIWYTADGERKSSSPANNRHCFYHGEVRGVDGSSVAVSTCSGLRGLISLNTS
VSYLIEPLSAAGGKEQHAVFRAESLQLPRGSCLHHPGNTGHKEELDDFIHGMMSPQLSRN
KRDLSQNMKYVELLLVADKAEFDKHGSNFEKTKLKLLEAANLVDKYYKVLNIRVALIGLE
VWTNVDMISVSDNPHSTLAAFLSWRSKQLRTLPNDNAQLITGRAFQGTTIGLAPLKAMCS
DYQSGGVNTDHSESAVGVAATMAHEMGHNFGMTHDSTGCCQARAEDGGCIMAAATGHPFP
RVFNDCNLKELRSYLTSGGGKCLFNLPNTRVMYGGQRCGNGYLEEGEECDCGEEEECTSL
CCNANNCTLRAGAECAHGVCCHKCKLKSPGVLCRAPSGSCDLPEYCDGRTESCPANFYLV
DGTTCASEQAYCYTGMCLTLEQQCQSLWGQDGRPAPELCFKKVNEAGDMFGNCGKDLLGR
YKTCKDRNAKCGKIQCLTSVSKPIENNAVRIETTVSVGNEKIRCMGTHVYKAGQVDEDTQ
SDTLDPGLVMTGTKCGVDSICFNGECRNASFLRADECNNKCNGHGLCNNNHNCHCDAGWA
PPLCEKKGFGGSLDSGPVINHSNLLPMLLGLPLVIFVALAVVGLWRCYGHKLSPLKSSAP
PPVPKYILSCSIPVEGKPLCADSQVSGHANPAFLLKKQELDRVSRNAPTRPGVKPPPVPP
GKKSEQAQKQAPPPPSGLLASRSPKNNSQPSTVPKPRPDPPNRPPPPCP

>Tetraodon nigroviridis_ADAM19(ENSTNIP_1335)
KHPSKALVVITAEGQQLRLDLEKNEQLLVPGYQEIWYTEDGARKSSSPANNRHCFYHGEV
WGVDGSSVAVSTCSGLRGLISLNSSTSYLIEPLSAAGGEAQHAVFRAESLHLPGGSCLHH
PSNTARREGLDDFIQGMMPPQPSRSKRDLSQNMKYVELLLVADKAEFDKHGSNLEKTKLK
LLEAANLVDKFYKALNIRVALIGLEVWTNGDMISVSDNPHSTLAAFLSWRSKQLRALPND
NAQLITGRAFQGTTIGLAQLKAMCSDYQSGGVNTDHSESAVGVAATMAHEMGHNFGMTHD
TAGCCQARSEDGGCIMAAATGHPFPRVFNDCNLKELRSYLSSGGGKCLFNLPNTRAMYGG
QRCGNGYLEEGEECDCGEEEECTSPCCNANNCTLRAGAECAHGVCCHNCKLKSPGVLCRA
ASGSCDLPEYCDGRTESCPANFYLVDGTSCAGGRAYCYTGMCLTLEQQCQSLWGQDGRPA
PELCFQKVNEAGNMFGNCGKDMMGKYRSCEDRDAKCGKIQCLTSASKPTENNAVRIDTTV
SQGTQRIQCVGTHVYKAGQGEEETQGDTLDPGLVMTGTKCGVDSICFNGECRNASFLKAD
ECNNKCNGHGLCNNNHNCHCDAGWAPPLCEKKGFGGSVDSGPVSTSVNLLPMLLVLPLLI
VVVLAGVGLWFWYRHKLNLPKSTPPPPAPRYTNDGQVSGHANPAFFLKKQELYRMVNTLP
PVKSEQKPSQAPPPPSGLLATLVPKNNSQPSAVPKPRPDPPTRPPPPCPVN

>Gasterosteus aculeatus_ADAM19(ENSGACP_24384)
SEFLQCSTRQLLAPGYQEIWYSPDGARRSSSPATTGHCFYHGEVQGMKGSSVAVSTCSGI
RGLISLNTSVSYLIEPLPVSTGAQQHAVFRAESLHLPGGSCPHHRGNEEREEGLNDFIHG
MMSPRSAREKRDVSQNMKYVELLIVADKAAFEKHGSSLQKTKLKLLEAANLVDKYYKALS
IRVALIGLEVWTSQDMISVSDNPHSTLAAFLSWRGKQLRTLPNDNAQLVTGRDFQGTIIG
LAPLKAMCSDYQSGGVNADHSELAVGVAATMAHEMGHNFGMSHDSTGCCQAKAEDGGCIM
AAATGHPFPRVFNGCNLKELKSYLNSGGGKCLFNLPNTRSMYGGQRCGNGYLEDGEECDC
GEEEECTSLCCNANNCTLKAGAECAHGVCCHDCKLKSPGVLCRAPSGSCDLPEYCDGKAE
SCPANFYLVDGTSCAAGRAYCYTGMCLTLEQQCRSLWGQDGRSAPDLCFKKVNEAGDMYG
NCGKDLFGKYRSCKERDAPCGKIQCLSSVSKPIANSAVRIETTVTAGNKKIQCLGTHVYM
PGQGEEKGQGDTLDPGLVMTGTKCAVDSLCFNGECRNASFLRADECNSKCNGHGLCNNNH
NCHCDAGWAPPLCVQKGSEILLPTGNLLPVLVVLPLVLFVILSAVALWCCYRHKLHGKPS
PRPSPSCSTRLAIVPPAVKPPAVPAYAAEQKGQTARAQIQPGVGQNSPASYTPPSVNSAK
LTKLRPNPPPPPPTGRPPVPSQSVASKLRPDPPTRPPPPCPLNKPSG

>Oryzias latipes_ADAM19(ENSORLP_9292)
MPAGERPRRVDAVRSMLCLIIAGLQCVSASEGCVHSGNQESRSIFEQIESYEITYPTWQH
PFRHRRSASKEHPAEIQVVVTAESQNLTLHLKKNEQLLAPGYQEIWYNPNGARQSSFLAN
TSHCLYHGEVLGIEESNVAVSTCSGLRGMISINTSLSYLIEPLHNSTNTQAHAIFQAKSF
RLSRGSCLHCHRTNEHGDTLNDFIYGMMSPWRTRRQDKRELGQNTKYVELLLVADKAEFQ
KHGYNLEKTKLKLLEAANLVDKFYKALNIRVALIGLEIWTTQDKINVSDNPHSTLAAFLS
WRRKQRQILPNDNAQLITGKSFQGTTIGLSPLKVMCSDYESGGVNTDHSDLAVGVAATMA
HEMGHNFGMTHDTKGCCQAKAEDGGCIMAPATGHPFPRVFNDCNRRELMSFLSSGGGKCL
YNLPNTKAMYGGQRCGNGYLEEGEECDCGEEEECTSPCCNASNCTLKAGAECAHGVCCHN
CKLKSPGVLCRPSSGPCDLPEYCDGKTESCPANFYLMDGTSCADGKAYCYTGMCLTLDLQ
CRSLWGGDGRSAPDKCFTEVNKAGDMYGNCGKDLLGKYRSCTDRDAKCGKIQCSTSATKP
VGNNAVIIETSITDGKKKIYCKGTHVYKLPHGDPEPQTDALDPGLVMTGTKCGDNSICFH
GECRNNSFLKADECNSKCHGHGVRCASINKKMSWIDLRMLQLKPKKQLCSWIFSSCSSYA
TTTATATATRAGRHLNVTKRGQEGVWTVDLSSAKVTSWHTFCLFFWLLLCSWLLLDFGAT
EHISSSHSKSPHQLLHCHVQSQLKRSLCVLSTR

>Homo sapiens_ADAM20(ENST_256389)
MVQLHQDTDPQIPKGQPCTLNSSEGGARPAVPHTLFSSALDRWLHNDSFIMAVGEPLVHI
RVTLLLLWFGMFLSISGHSQARPSQYFTSPEVVIPLKVISRGRGAKAPGWLSYSLRFGGQ
RYIVHMRVNKLLFAAHLPVFTYTEQHALLQDQPFIQDDCYYHGYVEGVPESLVALSTCSG
GFLGMLQINDLVYEIKPISVSATFEHLVYKIDSDDTQFPPMRCGLTEEKIAHQMELQLSY
NFTLKQSSFVGWWTHQRFVELVVVVDNIRYLFSQSNATTVQHEVFNVVNIVDSFYHPLEV
DVILTGIDIWTASNPLPTSGDLDNVLEDFSIWKNYNLNNRLQHDVAHLFIKDTQGMKLGV
AYVKGICQNPFNTGVDVFEDNRLVVFAITLGHELGHNLGMQHDTQWCVCELQWCIMHAYR
KVTTKFSNCSYAQYWDSTISSGLCIQPPPYPGNIFRLKYCGNLVVEEGEECDCGTIRQCA
KDPCCLLNCTLHPGAACAFGICCKDCKFLPSGTLCRQQVGECDLPEWCNGTSHQCPDDVY
VQDGISCNVNAFCYEKTCNNHDIQCKEIFGQDARSASQSCYQEINTQGNRFGHCGIVGTT
YVKCWTPDIMCGRVQCENVGVIPNLIEHSTVQQFHLNDTTCWGTDYHLGMAIPDIGEVKD
GTVCGPEKICIRKKCASMVHLSQACQPKTCNMRGICNNKQHCHCNHEWAPPYCKDKGYGG
SADSGPPPKNNMEGLNVMGKLRYLSLLCLLPLVAFLLFCLHVLFKKRTKSKEDEEG

>Pan troglodytes_ADAM20(ENSPTRP_52582)
MVQLHQDTDPQIPKGQPCTLNSSEGGARPAVPHTLFSSALDRWLHNDSFIMAVGEPLVHI
RVTLLLLWFGMFLSISGHSQARPSQYFTSPEVVIPLKVISRGRGAKAPGWLSYSLRFGGQ
RHIVHMRVNKLLFAAHLPVFTYIEQHALLQDQPFIQDDCYYHGYVEGVPESLVALSTCSG
GFLGMLQINDLVYEIKPISVSATFEHLVYKIDSDDTQFPPMRCGLTEEKIAHQMELQLSY
NFTLKQSSFVGWWTHQRFVELVVVVDNIRYLFSQSNATTVQHEVFNVVNIVDSFYHPLEV
DVILTGIDIWTASNPLPTSGDLDNVLEDFSIWKNYNLNNRLQHDVAHLFIKDTQGMKLGV
AYVKGICRNPFNTGVDVFEDNRLVIFAITLGHELGHNLGMQHDTQWCVCKLQWCIMHAYR
KVTTKFSNCSYAQYWDSTISSGLCIQPPPYPGNIFRLKYCGNLVVEEGEECDCGTIQQCA
KDPCCLLNCTLHPGAACAFGICCKDCKFLPSGTLCRQQVGECDLPEWCNGTSHQCPDDVY
VQDGISCNVNAFCYEKTCNNHDIQCKEIFGQDARSASQSCYQEINTQGNRFGHCGIVGTT
YVKCWTPDIMCGRVQCENVGVIPNLIEHSTVQQFHLNDTTCWGTDYHLGMAIPDIGEVKD
GTVCGPEKICIRKKCASMVHLSQACQPETCNMRGICNNKQHCHCNHEWAPPYCKDKGYGG
SADSGPPPKNNMEGLNVMGKLRYLSLLCLLPLVAFLLFCLHVLFKKRTKSKEDEEG

>Canis familiaris_ADAM20(ENSCAFP_24513)
MSALHPKQLTGRSQTSSTPHPALSSALDRWLHDDSSIMALGEALVHITVTLLILWVGMSL
FISGHSQAMPSQHFSPELVIPLKVTGRGRSAKSPGWLSYSLKFGGQRHIVHMRVKKFLLS
KHFPVFTYTDQHALLQDQPFVPDDCYYHGYVEGISESLVALSTCSGGFRGMLQINDLAYE
IEPISFSATFEHLVYKIDSGDTQFPPMRCGLTEEEIARHLQLRASYNSTLMQNSYLGWWT
HLRFVELVVVVDHFRYLYCKSNVSLVQREVFDTVNIIGILYSPLEVEIVLNGIEIWSERN
LISTDTIEQILGDFSAWKFSNLDDRLPHDTAHLFIKKNFGIKLGVAYVGGICHRLFNSGV
DVFEEDRLYLFALTVTHELGHNMGMTHDTKECKCGLPWCIMYDSQSVTARFSNCSYAEYW
NNILTKGLCIHSPPYPGNVFKVQYCGNLVIEEGEECDCGTTDQCVNDPCCLLNCTLKPGA
ACQFGICCKDCKLMPSGTLCRHQISECDLPEWCNGTFHQCPEDVYVQDGIPCGDNAYCYE
GRCNNHDKQCREIFGKDARSASQSCYKEINTQGNRFGHCGITNLVYVKCEGPDILCGRVQ
CENVEMIPNLIQHSTVHQLHINDTTCWGTDFHLGMSIPDVGQVKDGTICGPEKICLHKKC
VNMTYPPRKCHSNETCHMHGVCNNKQHCHCKHGWAPPYCKDAGLGGSVDSGPPPKEYVAT
LEAKALLGYLSLLWLIPFTAFVLFCLLVVCMEKKREEEN

>Bos taurus_ADAM20(ENSBTAP_51721)
MTVGEALVHFRVTPLLLWFGVCLFISGHSQARPSQHFSSPELVIPLKVTGWGRNAKVPGW
LSYSLRFGGQRHIAHMKVKKFLVSRPLPVFTYTDQRSLQQDQPFVPDDCYYHGYVEGAPK
SLVALSTCSGGFRGILQINDLAYEIEPVRSSATFEHWVYRIDINDTQFPRMRCGLTEEEI
ARQLELHNFTLKQSSYTGWWTHLRFLELVVIVDNLRYIFSGSNVSVVQNDIANAVNIINS
LYRPLAVDVILTGLEIWTEINQIATDDIENMLEDFAVWKFFNLDKRLPHDAAHLFIKKSF
DPTLGVAFVAGVCQNPLNSGVMVFEDESLYAFGLTVTHELGHNLGMLHDTEFCVCELQFC
IMYPARSVTSKFSNCSYAEFWDNVMRNGLCLFSPPNPENIFRIKYCGNLVVEEGEECDCG
TIGQCARDPCCLPNCALKPGAACAFGSCCKNCKVRSAGTLCRKQVNECDLPEWCNGTSHQ
CPEDVFVQDGIPCSDSAYCYKKNCANHDEQCREIFGKDARSASQSCYKEINTQGNRFGHC
GISNTEYMKCEVPDILCGRVQCENVGVIPNLMEHSTVHQFQVNDTTCWGTDYHVGMSIPD
IGQVKDGTMCGQKKICVHSRCVSMVPEPQACQPKTCHMKGVCNNKQECHCNPGWAPPYCK
DEGSGGSNSSGPPGNPQGDTHMLLWLIPLICLFVCCFLVLCKKRKEKKEP

>Homo sapiens_ADAM21(ENST_603540)
MAVDGTLVYIRVTLLLLWLGVFLSISGYCQAGPSQHFTSPEVVIPLKVISRGRSAKAPGW
LSYSLRFGGQKHVVHMRVKKLLVSRHLPVFTYTDDRALLEDQLFIPDDCYYHGYVEAAPE
SLVVFSACFGGFRGVLKISGLTYEIEPIRHSATFEHLVYKINSNETQFPAMRCGLTEKEV
ARQQLEFEEAENSALEPKSAGDWWTHAWFLELVVVVNHDFFIYSQSNISKVQEDVFLVVN
IVDSMYKQLGTYIILIGIEIWNQGNVFPMTSIEQVLNDFSQWKQISLSQLQHDAAHMFIK
NSLISILGLAYVAGICRPPIDCGVDNFQGDTWSLFANTVAHELGHTLGMQHDEEFCFCGE
RGCIMNTFRVPAEKFTNCSYADFMKTTLNQGSCLHNPPRLGEIFMLKRCGNGVVEREEQC
DCGSVQQCEQDACCLLNCTLRPGAACAFGLCCKDCKFMPSGELCRQEVNECDLPEWCNGT
SHQCPEDRYVQDGIPCSDSAYCYQKRCNNHDQHCREIFGKDAKSASQNCYKEINSQGNRF
GHCGINGTTYLKCHISDVFCGRVQCENVRDIPLLQDHFTLQHTHINGVTCWGIDYHLRMN
ISDIGEVKDGTVCGPGKICIHKKCVSLSVLSHVCLPETCNMKGICNNKHHCHCGYGWSPP
YCQHRGYGGSIDSGPASAKRGVFLPLIVIPSLSVLTFLFTVGLLMYLRQCSGPKETKAHS
SG

>Pan troglodytes_ADAM21(ENSPTRP_11006)
MAVDGTLMYIRVTLLLLCLGVFLSISGYCQAGPSQHFTSPEVVIPLKVISRGRSAKAPGW
LSYSLRFGGQKHVVHMRVKKLLVSRHLPVFTYTDEHALLEDQLFIPDDCYYHGYVEAAPE
SLVVFSACFGGFRGVLKISGLTYEIEPIRHSATFEHLVYKINSNETQFPAMRCGLTEKEV
ARQQLEFEEAENSALEPKSAGDWWTHAWFLELVVVVNHDFFIYSQSNISKVQEDVFLVVN
IVDSMYKQLGTYIILIGIEIWNQGNVFPMTSIEQVLNDFSQWKQISLSQLQHDAAHMFIK
NSLISILGLAYVAGICRPPIDCGVDNFQGDTWSLFANTVAHELGHTLGMQHDEEFCFCGE
RGCIMNTFRVPAEKFTNCSYADFMKTTLNQGSCLHNPPRLGEIFMLKRCGNGVVEREEQC
DCGSVQQCEQDACCLLNCTLRPGAACAFGLCCKDCKFMPSGELCRQEVNECDLPEWCNGT
SHQCPEDRYMQDGIPCSDSAYCYQKRCNNHDQHCREIFGKDAKSASQNCYKEINSQGNRF
GHCGINGTTYLKCHISDVFCGRVQCENVRDIPLLQDHFTLQHTHINGVTCWGIDYHLRMN
ISDIGEVKDGTVCGPGKICIHKKCVSLSVLSHVCLPETCNMKGICNNKHHCHCSYGWSPP
YCQHRGYGGSIDSGPASAKRGVFLPLIVIPSLSVLIFLFTVGLLMYLRQCSGPKETKAHS
SG

>Mus musculus_ADAM21(ENSMUSP_8582)
MECFIMLGADARTLMRVTLLLLWLKALPSLIDLSQTGSTQYLSSPEVVIPLKVTSRARGA
KNSEWLSYSLVFGGRRHVVHMRVKKLLVSTHIPVLTYTEEHTPLSDYPFVPSDCYYHGYV
EGALESLVAFSACNGGLQGVLQMNGFSYEIEPIKHSSTFEHLVYTLNNNKTQFPPMLCSL
TEKRLLYQPFGVEEAKKSAMKQNYGKLWPHMWFLELAVVVDYGFFTNAQQNLSKVRGDVV
LVVNMVDSMYKPLDTYVTLVGIEIWNRGNVLPMENIHQVLEDFSHWKQISLSQVHHDAAH
IFIRSSLISVLGIAYIAGICRPPLDCGVENFQGDAWSLFANTVAHELGHTFGMKHDEESC
SCGKSGCVMSTFRVPAERFTNCSYSDFMKTTLNQGTCLYNHPRPGAGFLVKRCGNGMVES
EEECDCGSVQECEQDPCCFLNCTLRPAAACSFGLCCKDCKFMLLGELCRPKINECDLPEW
CNGTSHQCPEDGYVQDGVPCGAGAYCYQKQCNNHDQQCREIFGKGARSASHNCYKEINLQ
GNRFGHCGTDGTVFLKCRMSDVFCGKVHCENVEDIHHPQAPYVLQNIYANGITCWSTGHC
LGMGVPDVGEVKDGTTCGVGKICLHKKCVSLSVLSNACLPETCNRKGVCNNKHHCHCDYG
WSPPFCLHRGYGGSIDSGPTSQKRRVIITVLSITVPVLSILICLLIAGLYRIYCKIPSGP
KETKASSPG

>Canis familiaris_ADAM21(ENSCAFP_24506)
SSIMVAGEAEVPMRVLLLFWVGMSLFPSGFSQAGPSQYLRSPEVVTPLKVTDRGRSAKSP
GWLSYSLKFGGQRHIVHMRVKKLLVSKHFPVFTYTDQHALLQDQPFVPDDCYYHGYVEGI
SESLVALSTCSGGFRGMLQINDLAYEIEPIRHSTKFEHLVYEINTNETQFPTMRCGLTKK
EIALQQVKFEEVKKSTLKQNSNDKLWTHSWFLELVVVVDHNFLIYSQSNFSMVQEDVFLV
VNIVDSIYQQLGTYVILIGIEIWNQGNVFPMISIEQVLEDFSKWKQISLSQLQYDAAHFF
IKNPLISVLGIAYVAGICRPPIDCGVNNFQGDSWSLFALTVAHELGHTLGMWHDEEFCLC
EQSGCIMNAMRVPAEKFTNCSYIDFTKTTLNQGSCLHNIPHPGEVFTLKHCGNGVVEGEE
ECDCGSIKQCEQDPCCLLNCTLRPRAACAFGLCCKGCKFMPSGELCRHQVNKCDLPEWCN
GTSHQCPEDVYVQDGIPCGDDAYCYEGRCNNHDKQCREIFGEGAKSAYQSCYQEINSLGN
RFGHCGISGTTYLKCNISDIFCGRVQCDNVTNIPHLRDHSTLQQTHINGVTCWSIDYHLG
MDTPDVGEVKDGTMCGTGKICIRKKCVSLSLLSQVCLAETCNMRGICNNKHHCHCGYGWS
PPYCLHRGYGGSVESGPASAKKGFLLLVVSLILSVLLLLSTAVFIYHRKTFGLKETKAQS
SG

>Bos taurus_ADAM21(ENSBTAP_4838)
AQREEPGQQCLISSSLDRWLHSGCSIMVTGEARVSMQVVGLLWLEVSLFSSGLSQERRSQ
SLNSPDVVIPLKVTNGSRGPNAPGWLSYSLQFGGQRRVVYIRPKKILVSKALPVFTYTDQ
HALQQDQPFVPNDCYYHGYVEGVPESLVALSTCAGGFQGMLRINDFTYEIKPIRHSTTFE
HLVSKINTKETQFSPMRCGLTNKAAHQQLEFKEAEKLTLKQNSAYNRWAHLWFLELVVVV
DHNFFIYSQSNFSKVQENVFVVVNIVDSIYQQLGTYVILMGIEIWNYGNVFPLISIEQVL
EDFSQWKQISLSQLQYDAAHIFIENSLISVLGIAYVAGICHPPLDCGVNNFKGDPWSVFA
LTVAHELGHTLGMKHDEEFCVCGQSACIMNAIRLPAERFTNCSYAEFTKTTLNQGSCLHN
LPIPEAVFMLNHCGNGVIEGEEKCDCGSIKQCEQDPCCLLNCTLRPGAACAFGLCCKDCK
FMPSGELCRPQINECDLPEWCNGTSHQCPEDVHVQDGIPCSDSAFCYQKSCNSHDEQCRE
IFGEGAKSASQRCYKEINSQGSRFGHCGVNGTTYLKCPISDSFCGRVHCENVGNIPHLRD
HSNLQYTHINGVTCWSTDYHLEMSIPDIPDVGEVKDGTMCGPGKICIHKKCVSLSLLSRA
CLPETCNMKGICNNKHHCHCGYGWSPPYCLHRGTGGSVDSGPASARRAFLPTVVPLGLFV
LLLPLIAVFMYLQKRFRPKKTKTHSPN

>Homo sapiens_ADAM28(ENST_265769)
MLQGLLPVSLLLSVAVSAIKELPGVKKYEVVYPIRLHPLHKREAKEPEQQEQFETELKYK
MTINGKIAVLYLKKNKNLLAPGYTETYYNSTGKEITTSPQIMDDCYYQGHILNEKVSDAS
ISTCRGLRGYFSQGDQRYFIEPLSPIHRDGQEHALFKYNPDEKNYDSTCGMDGVLWAHDL
QQNIALPATKLVKLKDRKVQEHEKYIEYYLVLDNGEFKRYNENQDEIRKRVFEMANYVNM
LYKKLNTHVALVGMEIWTDKDKIKITPNASFTLENFSKWRGSVLSRRKRHDIAQLITATE
LAGTTVGLAFMSTMCSPYSVGVVQDHSDNLLRVAGTMAHEMGHNFGMFHDDYSCKCPSTI
CVMDKALSFYIPTDFSSCSRLSYDKFFEDKLSNCLFNAPLPTDIISTPICGNQLVEMGED
CDCGTSEECTNICCDAKTCKIKATFQCALGECCEKCQFKKAGMVCRPAKDECDLPEMCNG
KSGNCPDDRFQVNGFPCHHGKGHCLMGTCPTLQEQCTELWGPGTEVADKSCYNRNEGGSK
YGYCRRVDDTLIPCKANDTMCGKLFCQGGSDNLPWKGRIVTFLTCKTFDPEDTSQEIGMV
ANGTKCGDNKVCINAECVDIEKAYKSTNCSSKCKGHAVCDHELQCQCEEGWIPPDCDDSS
VVFHFSIVVGVLFPMAVIFVVVAMVIRHQSSREKQKKDQRPLSTTGTRPHKQKRKPQMVK
AVQPQEMSQMKPHVYDLPVEGNEPPASFHKDTNALPPTVFKDNPVSTPKDSNPKA

>Pan troglodytes_ADAM28(ENSPTRP_34390)
MLQGLLTVSLLLSVAVSAIKELPGVKKYEVVYPIRLHPLHKREVKEPEQQEQFETELKYK
MTVNGKIAVLYLKKNKNLLAPGYTETYYNSTGKEITTSPQIMDDCYYQGHILNEKVSDAS
ISTCRGLRGYFSQGNQRYFIEPLSPIHQDGQEHALFKYDPDEKNYDSTCGMDGVLWAHDL
QQNIALPATKLVKLNDRKVQEHEKYIEYYLVLDNGEFKKYNENQDEIRKRVFEMANYVNM
LYKKLNTHVALVGMEIWTDKDKIKITPNASFTLENFSKWRGSVLSRRKHHDIAQLITATE
LAGTTVGLAFMSTMCSPYHSVGIVQDHSDDLLRVAGTMAHEMGHNFGMFHDDYSCKCPST
ICVMDKALSFYIPTDFSSCSRLSYDKFFEDKLSNCLFNAPLPTDIISTPICGNQLVEMGE
DCDCGTSEECTNICCDAKTCKIKATFQCALGECCEKCQFKKAGMVCRPAKDECDLPEMCN
GKSGNCPDDRFQVNGFPCHHGKGHCLMGTCPTLQEQCTELWGPGTEVADKSCYNRNEGGS
KYGYCRRVDDTLIPCKANDTMCGKLFCQGGSDNLPWKGRIVTFLTCKTFDPEDTSQEIGM
VANGTKCGDNKVCINAECVDIEKAYKSTNCSSKCKGHAVCDHELQCQCEEGWSPPDCDDS
SVVFHFSIVVGVLFPMAVIFVVVAIVIRHQSSREKQKKDQRPLSTTGTRPHKQKRKPQMV
KAVQPQEMSQMKPHVYDLPVEGNEPPASFHKDTKALPSTVFKDNPMSTSKDSNPKA

>Mus musculus_ADAM28(ENSMUSP_22642)
MQQWSLLVVSFLLSPVPVSAIKELPKAKKYEVVYPIRLHPLRKRETQEPEPKETFETELR
YKMTVNGKVAVLYLKKNNKLLAPDYSETYYNSSGNKVTTSPQIMDSCYYQGHIVNEKVSA
ASISTCQGLRGYISQGDEKYFIEPLSSENLDEQAHALFKDDSNEDQEKSNCGVDDALWLQ
GLHQDVALPATRLIKLNDGMVQEPKKYIEYYVVLDNGEFKKYNKNLAEIRKIVLEMANYI
NMLYNKLDAHVALVGVEIWTDGDKIKITPDANTTLENFSKWRGNDLLKRKHHDIAQLISS
TDFSGSTVGLAFMSSMCSPYHSVGIVQDHSNYHLRVAGTMAHEMGHNLGMIHDYLSCKCP
SEVCVMEQSLRFHMPTDFSSCSRVNYKQFLEEKLSHCLFNSPLPSDIISTPVCGNQLLEM
NEDCDCGTPKECTNKCCDARTCKIKAGFQCALGECCEKCQLKKPGVVCRAAKDECDLPEV
CDGKSSHCPGDRFRVNGSPCQNGHGYCLKGKCPTLQQQCMDMWGPGTKVANTSCYKQNEG
GTKYGYCHVENGTHMPCKAKDAMCGKLFCEGGSGDLPWKGLTISFLTCKLFDPEDTSQGV
DMVANGTKCGTNKVCINAECVDMEKTYKSANCSSKCKGHAVCDHELQCQCKEGWAPPDCE
NSATVFHFSIVVGVLFPLAVIFVVVAIVIQRQSARRKQRRVQRLPSTKDAKLHNQKCRPQ
KVKDVQPQEMSQMKKLHVSDLPSEEPEPPPDVLITKPNFPPPPIPVSLTGRAKVPFVKTP
HPFSQQIGRVYLK

>Rattus norvegicus_ADAM28(ENSRNOP_55507)
MQQWRLLVVWFLLSPVPASAIKELPKAKNYEVVYPIRLHLLHKRETKEPEPKETFETELR
YKMTVNGKVVELYLKKNNKLLAPGYLETYYNSSGNKVTTSPQIMDSCYYQGHIINEKDSA
ASISMCQGLRGYFSQADERYFIEPLSSEILDEQAHALFKDDPKEDQENSNCGVDDALWLQ
GLHQDVVLPATRLIKLNDGMVQEPKKYIEYYVVLDNGEFKKYNKNLDEIRKRVHEMANYV
NMLYNKLDAHVALVGMEIWTDEDKIKITPDANTTLENFSKWRGNDLLKRKHHDVAQLISS
TDFSGSTVGLAFMSSMCSPYHSVGIVQDHSNYHLRVAGTMAHEMGHNLGMIHDYLSCKCP
SEVCVMEQSLRFHMPTDFSSCSRDNYRRFLEEKLSHCLFNSPLPSDIISTPVCGNQLLEM
NEDCDCGTPKECTNKCCDAETCKIKAGFQCALGECCEKCQLKKPGVVCRAAKDECDLPEM
CDGKSSHCPVDRFRVNGFPCQNGHGYCLKGNCPTLQQQCMDMWGPETKVANKSCYKQNEG
GSKYGYCHVENGTHMPCKAKDAMCGKLFCEGGSGDLPWKGLTIAFLTCKLFDPEDINQGV
DMVANGTKCGNNKVCINAECVDMEKTYKSANCSSKCKGHAVCDHELQCQCKEGWAPPDCE
DSATVFRRRLHHGWRALSSGSHICGDCYSDPSSKCQKKAKESSEATTHQGCQATQAEV

>Canis familiaris_ADAM28(ENSCAFP_13383)
MSPEFHSVLLEQRQGQRRSRGAVLSQGARREGAAPLNSPIMLQGILLTTTFLLWPVPVNT
IKELPGIKNYEVVYPRRLHPLHKREVKDPDQQEKFETELKYKMTVNGKIAVLYLKKNNGL
LAPGYTETHYNSTGEEITTSPQIMDDCYYQGHIINEKVSDASISTCRGLRGYFSQGDQKY
LIEPLSPTNDDGQEHALFKYDPHEKKTNSTCGMDNILWAHGSRQSVATRLVKSNDQKGPE
RKKYIEYYLVLDNGEFKKYNQDREKIRKRVFEMANYVNMLYKKLNTHVALVGIEIWNDED
KIKITPNASSTLENFSKWRGSVLRKRKPHDIAQLITATKLSGTTVGLAFMSTMCSPYHSV
GIVQDHSSNVLRVAGTMAHEMGHNFGMFHDSYVCKCPSTICVMDRALSFYLPTDFSSCSR
VSYDKFFEDKLSNCLFNAPLPTDIISIPICGNQVVEMGEDCDCGTPEECTNICCDAKICK
IKANFQCAIGECCEKCQFKKAGAVCRPAKDECDLPEMCDGKSGICPDDRFRVNGFPCQNG
KGYCLMGLCPTLQEQCTELWGSGTKVADRSCYSRNEGGSKYGYCRKVEDRPIPCKASDAM
CGKLFCQGGSDNLPWRGHIVTFLTCKTFNPEDSSQEIGMVANGTKCGNKKVCINAECVDI
ERAYKSTNCSSKCKGHAVCDHELQCQCKEGWAPPDCDDSSVVFHFSIVVGVLFPVAVISV
VVAVVIWHQSTRGKQKEVQRPLSTTGTRPRRQKRNPQTGKAVQPQEMSQMKLHSPDLPVE
GNEPPASFLITKPDFPPPPIPTSVSSSFLGSDPKV

>Monodelphis domestica_ADAM28(ENSMODP_20933)
LLSPDYVEVRYSSTGEAVTTSPQIMENCYYQGHILNEEMSTASVSTCQGLRGFFEHQEQS
YLIEPLGPREHEEQEHALYTYESQEQNPPETSCGVDMVEEEEPFVERTLRIGNNAMVRKQ
EDMNQKKYIEYYLVLDNKVFRKYNRSPEQIRQRVFDMVNFVNMLYKKLNVQVALVGMEIW
TNGNKIKISPNANVTLENFSNWRGDILPKMKHHDIAQLITGIDLTGPTVGLAFMSTMCSP
YRSVGIVQDHSYDLLRVAGTMAHEMGHNFGMYHDSYECKCPSSICVMDWALSFYIPKDFS
SCSRDSFEKFLRRASPDCLKNVPLPDDIISTPICGNLIVEIGEECDCGSSEECTNACCDA
ATCKIKPNFKCAFGECCEKCQIKKAGTLCRPVKDECDLPEMCDGKSGSCPEDRFRVNGFP
CKNGQGYCLMGKCPTLQDQCVSLWGKGAQAAEKSCFNVNNGGSTYGYCRKVDDTYIPCKA
GSSMCGKLYCYGGSDFLPWKGKIMSFLTCKTFSSEDNNQEISMVANGTKCGNNSVCINGE
CKDIESAYKSTNCSLKCKGHAVRSNYCCLNA

>Danio rerio_ADAM28(ENSDARP_89375)
MAQRHLMLWIFTLCVSLDPSVGHIHELHGKVYEIVRPIRLHDLQKRDLQSRPDRVKYAMT
LGGRDIEMHLQKNTGMLTKDYSETYYTDDGMLVTTTPADLDLCYYHGKILNDSASLVSMS
TCDGLRGYFQTAEQRFLIEPLSEDSDGDHAVFKYEDVNEATPRVCGVTNTTWDESGDGVP
PRILKTRSRSSGPTLFQRQKYNEFFLVADNREYKKLNSDLEKLRKRIFEIINFINNVYKE
INTFVALTGFEVWTDNDKITVSAASGATLDSFTKWRNSDLIKRQRHDNAHLLTAIDLDGA
TVGLAYIGTLCGGLSTGIVQDHNSMATAVGATIAHEMGHNLGMNHDSSSCVCSDSSCIMT
AALSYFIPQHFSSCSTGAFVDYLNNKVPECLLNKPQPRDLLQPAVCGNGFVEIGEECDCG
TVQECKNPCCNATTCKLTVGSQCAAGECCDNCKIMSASHVCRPKADDCDLPESCTGKSAE
CPEDVFTVNGVPCKNGKGYCYNGQCPMKEEQCIKMWGSTSVVARDSCYSQNTRAEYYAYC
KRNGDKYIGCQKQDIMCGKLFCESGNDNPNYGRLVTFSNCKATFYGSPDEDYGQVDTGTK
CGEGLVCNQNECVGLETAYKATNCSNKCKGHGVCDHRLQCKCEPGWLPPDCDKPAESEGL
SKGVTIAISVIVTIVIVILLIGLTVFLCKRRTSTPHAYRGQPRQQKVHVVDIPDLSQQRS
ATPNQKPTPVIKPSAPPPPPPYSVHAPHNEFMAARQVAQLNI

>Takifugu rubripes_ADAM28(ENSTRUP_12704)
LHYLLYVFMYFTCVSTESHSHEFGEVMHYQVVRPVRLHSLRKRGTESVRPETVKYAMTLG
GRDIEMHLERNDELLTKDYTETYYQEDGSRVTAAPNDIDHCYYHGRIAGHSSSSVSISTC
DGLRGYFRTSAQRYLIEPLSGGDEGNHAVMTLNAGNSTPRVCGVTNTSWSDDFEPPTGRS
RSRSGEVSCRRQGFGIVQQQKYLELYLVGDFRMYEKLKRDRNAVRKRMFEIVNFVNMAYK
PLRTFIALVGLEIWSNGDQISVTPPAGANLNAFMKWRNNELLKRKKHDNAHLISGIDFEG
GTVGLAFIGTLCSGHSVGVVQDHNDRAIAIGATLAHEMGHNLGMDHDDSSACVCSGDSCI
MAAALSWNIPRTFSSCSNNNYEKYLLNRSPSCLLNKPDYLSIEAPAVCGNGFKEKGEQCD
CGTLQECTNPCCNATTCRLTEGSQCAEGDCCDNCKIAPRSKECRRKEDECDLEEYCDGQE
AVCPEDVFAVNGLPCEEGRGYCYNGNCPQRPDQCVKMYGVGAIEAARYCYDKNTRGTYFA
FCKRTAAQYIPCQAEDVMCGKLFCHNGQGNPNYGRMVQFGNCKASFFDDEDHTKDYGQVD
AGTKCGDGMVCSQNECVELKTAYRNTNCSARCSGHAVCNHKNQCQCTPGWMPPDCTSEDG
QFSLSKKGVIGVAVAVILVLLGLIAAVLAFLWTHAQRKPARPREQPGTRPYTAPPPVQFM
QPSKPAVVKPRIAPPP

>Tetraodon nigroviridis_ADAM28(ENSTNIP_22049)
VRDYQVVRPVRLHSLRKRDAERPPPQGGRPKRLSYGLRLGGEDVEMQLEQNDELLTKDYT
ETSYREDGTRVTVTPEDMDRCYYQGRLARQRHSSVSISTCNGLRWGYIRTGAQRYLIEPL
SADDQGDHALMTFNPGSSAPAVCGVTNTSWSSDFEPPTGRSRSRSGQQKYLELYLVADFR
MYEKQQRDEKAVKTRIFYIVNFVNMAYKPLQIFVALVGMEVWSSGDQISVTPPAGATLDA
FMRWRNDQLVKWKKHDNAHLISGIDFEGATVGLAFIGTLCSGHSVGVVQDHNDRAIAIGA
TLAHEMGHNLGMNHDDSSACACSGDSCIMAAALSWNIPQTFSSCSATSLEKFLVERGSAC
LLDRPDQDSLQAPPICGNGFVEQGEQCDCGKVQDCTNTCCNATTCRLTEGSQCAEGDCCD
DCKLAPRSRECRQKEDECDLAEFCDGQSNVCPEDVFAVNGLPCDGGWGYCYNGSCPQRSA
QCNRMYGSGATEAGRFCYDYNTKGTYFAFCKRPEKDLYIPCKAEDVMCGKLFCHGGQPNP
NYGRMVTIGTCKASFYDDHTKDHGQVDPGTRCGEGKVCSWNACVDLQAAYRNANCSARCS
GHAVCNHKNACQCLPGWLPPDCTAADGHLDQLTKTLVGVAVVLVLLGLV

>Gasterosteus aculeatus_ADAM28(ENSGACP_6843)
MQMWSQMNSLTISYLHSFPLESRGHDLEDVKDYEVVRPVRLHSVRRRHAEHLRPETVRYA
MTLGGRDIEMRLKRNHELLTKDYTETYYQADGTRVTAAPDDIDHCYYHGSIVNDSQSSVS
ISTCDGLRGYFRTSAQRYLIEPLSGGDGGDHAVMTFEEKNSPPAVCGVTNTSWSDDYEPP
TSQSRSKSRTISITQKQKYIELFIVADNRAYVKMERDQTRLRKRIFEIVNFINMAYKPLR
TFIALVGLEIWSERDLFTVTPPAGANLNAFMMWRNSELLKRKQHDNAQFISGIDFEGATV
GLAYIGTLCSGHSVGVIQDHNDRAIAVGATMAHEMGHNLGMDHDDSITCACSADSCIMAA
ALSWNIPRTFSSCSGNEYEKYLLGRNPECLLDKPDFSDLLPPSVCGNGFLEKGEQCDCGS
ETECTNLCCNATICTLKEGAQCAEGECCEDCKVSPRSTECRRKQDECDLAEYCDGQSPIC
PEDVFGVNGLPCGADLGYCFDGRCPQRVNQCGKMFGGDATEGESFCYNQNTRGTYFAFCK
RPEKETYIPCQKEDVLCGKLFCHGGNVSPNYGRMVTVRNCKGTFYDDPTKDYGQVDTGTK
CGDGKVCSQNECVQLETAYRNVNCSAKCPGHAVCNHRSECQCEPGWLPPQCDSQDAAF

>Oryzias latipes_ADAM28(ENSORLP_20216)
LSQCSALWVSMLTDSHSVQVQQEKEKDYEVVRPVRLHTLRKRDAEHSRPPVIRYAMTVGG
KDIEMHLEKNNKLLTKEYSETYYQEDGTQVTTIPHDIDHCYYQGKIVNDSESSVSISTCD
GLRGYLRTSAQKYVIEPLSGSDEGDHTLKTFSEETAPPPVCGVTNNSWSEDFEPPTSRIQ
SRFGGRSIVQQQKYIELFLVADNREYLKMNKDMQKLRQRVFEIVNFVNLVYKPLKTFIAL
VGLEVWSNGDLIAITNPAGQNLDAFTKWRNSELKKRKNHDNAHLISGIDFEGSTVGLAFV
GTLCSDHSVGVIQDHNNNAIAVGATLAHEMGHNLGMNHDDSSACACAGDSCIMAAALSWN
VPRSFSSCSSSTYERYLTDRSPSCLLDKPDYKSLETPPVCGNGFKEEGEQCDCGTLNECT
NPCCNATTCKLTEGSQCAEGQCCENCKILPTTRECRRQQDDCDLAEYCDGKSNTCPEDVF
AVNGLPCDRGLGYCYNGQCPQRPNQCVKMFGGSATDASRSCYHFNTKGQYYGFCKRPSNQ
VYIPCQQQDILCGKLYCEGGNDNPNYGRMFTINNCKGSFSDDYTKDYGQVDTGTKCGDGM
VCGQNECMELEKAYRNTNCSAKCAGHGVCNHRSECQCEPGWLPPYCNIQDGEFRALSTGA
TVAIALPIILVILGVVLGVAGFMWKKRQGPVLP

>Homo sapiens_ADAM29(ENST_618444)
MKMLLLLHCLGVFLSCSGHIQDEHPQYHSPPDVVIPVRITGTTRGMTPPGWLSYILPFGG
QKHIIHIKVKKLLFSKHLPVFTYTDQGAILEDQPFVQNNCYYHGYVEGDPESLVSLSTCF
GGFQGILQINDFAYEIKPLAFSTTFEHLVYKMDSEEKQFSTMRSGFMQNEITCRMEFEEI
DNSTQKQSSYVGWWIHFRIVEIVVVIDNYLYIRYERNDSKLLEDLYVIVNIVDSILDVIG
VKVLLFGLEIWTNKNLIVVDDVRKSVHLYCKWKSENITPRMQHDTSHLFTTLGLRGLSGI
GAFRGMCTPHRSCAIVTFMNKTLGTFSIAVAHHLGHNLGMNHDEDTCRCSQPRCIMHEGN
PPITKFSNCSYGDFWEYTVERTKCLLETVHTKDIFNVKRCGNGVVEEGEECDCGPLKHCA
KDPCCLSNCTLTDGSTCAFGLCCKDCKFLPSGKVCRKEVNECDLPEWCNGTSHKCPDDFY
VEDGIPCKERGYCYEKSCHDRNEQCRRIFGAGANTASETCYKELNTLGDRVGHCGIKNAT
YIKCNISDVQCGRIQCENVTEIPNMSDHTTVHWARFNDIMCWSTDYHLGMKGPDIGEVKD
GTECGIDHICIHRHCVHITILNSNCSPAFCNKRGICNNKHHCHCNYLWDPPNCLIKGYGG
SVDSGPPPKRKKKKKFCYLCILLLIVLFILLCCLYRLCKKSKPIKKQQDVQTPSAKEEEK
IQRRPHELPPQSQPWVMPSQSQPPVTPSQSHPQVMPSQSQPPVTPSQSQPRVMPSQSQPP
VMPSQSHPQLTPSQSQPPVTPSQRQPQLMPSQSQPPVTPS

>Pan troglodytes_ADAM29(ENSPTRP_28496)
MKMLLLLHWLGVFLSCSGHIQDEHPQYHSPPDVVIPVRITGTTRGMKPPGWLSYILPFGG
QKHIIHIKVKKLLFSKHLPVFTYTDQGAILEDQPFVQNNCYYHGYVEGDPESLVSLSTCF
GGFQGILQINDFAYEIKPLAFSTTFEHLVYKMDSEEKQFSTMRSGFMQNEITCQMEFEEI
DNSTQKQSSYVGWWIHFRIVEIVVVIDNYLYIRYERNDSKLLEDLYVIVNIVDSILDVIG
VKVLLFGLEIWTNKNLIVVDDVRKSVHLYCKWKSENITPRMQHDTSHLFTTLGLRGLSGI
GAFRGMCTPHRSCAIVTFMNKTLGTFSIAVAHHLGHNLGMNHDEDTCRCSQPRCIMHEGN
PPITKFSNCSYGDFWEYTVERTKCLLETVHTKDIFNVKRCGNGVVEEGEECDCGPLKHCA
KDPCCLSNCTLTDGSTCAFGLCCKDCKFLPSGKVCRKEINECDLPEWCNGTSHKCPDDFY
VEDGIPCKERGYCYEKNCHDRNEQCRRIFGAGANTASETCYKELNTLGDRVGHCGIKNAT
YIKCNISDVQCGRIQCENVTEIPNMSDHTTVHWARFNDIMCWSTDYHLGMKGPDIGEVKD
GTECGIDHICIHRHCVHITILNSNCSPAFCNKRGICNNKHHCHCNYLWDPPNCLIKGYGG
SVDSGPPPKRKKKKKFCYLCILLLIVLFILLCCLYRLCKKSKPIKKQQDVQTPSAKEEEK
IQRRPHELPPQSQPWVMPSQSQPPVTPSQSHPQVMPSQSQPPVTPSQSQPWMMSSQSQTP
VMPSQRQPQLTPSQSQPWVTPSQSQPPVTPSQRQPQLTPS

>Mus musculus_ADAM29(ENSMUSP_54292)
MNMIEALLSMRVLFLTQVFGIFLCFPGLTKAGHLHYHSSIEVVIPMKVTEKTRGMNLPNW
ISYSLKLGGQRYIIHMKIKNLFLTRHLPVFTYSDQDSLLEDYPFVQDDCYYQGYVEGDSE
SLVSLSSCFGGFHGLLEINNIVYEIMPKKFSRKFEHLVYKVDSNKTESRGSSLMQDNITC
QVELQKSGNPILKQSSFEDWWTHTKIVELVVVVDKTLYDHYGNYTVMLSDLYSVINIVDT
IYEVIGIKILLVGVEVWNKKNLIVIDDVSKSLRLYCRWKASNFLHRLKHDVSHLFIYRHL
RGLSGIGSTGGICDPKRSCAVVTFIDRTLNLRAIGVAHHLGHNLGMKHDEDICKCSYSKC
IMHMDSPPIPKFSNCSYNYFWSYTVKNTRCLMENMYTKDIFDRTRCGNGVVEDKEQCDCG
SLRNCTNDLCCMSNCTLSTGSSCAFGLCCKNCQFLPSGTLCRKRDNICDLPEWCNGTSHE
CPDDAYVEDGIPCGVSAYCYEKQCNDRNEHCRQIFGQNAKTASVHCYREINTKGDRFGHC
GLQGPTYIKCKSNDALCGRIQCDNVVQIPNMKDHSTIHFALVKNVSCWGTDYHTGTSLTD
IGDVKDGTECEQNHICINRHCVHISTLDSNCTPAFCNYRGICNNKHHCHCNFHWDPPNCM
IRGHGGSVDSGLPPKTNKKKHFFYLLLLQLIILACLLSCLLWLLFNIKGSKRKPQVQPTP
VKTKKVSKKVPSQKPSPVPSPSLPQLRMPSRSASPTSSIKSTN

>Canis familiaris_ADAM29(ENSCAFP_33850)
MRIIPLLPWLGVFLSFCEYPQAEDPQYQNTPEVVIPLKIPDTSRGMKPSGWLSYSLRFGG
RRHIVHMKAKKYLLSRHLPVFTYTDQGALLEDQPFVPKDCYYHGYVEGDPESLVSLSSCS
GGFQGLLQINDFAYEIKPMTFSTKFEHLVYKMDSEKTQISGMNSDFMQEETVSQLESQKM
NNSTQKQSAYSSWWVHMYIMELAVVVDHSLYVHIKKNISKFNEDLYAMVNIVDSIYDGMG
LKLSLFGLEFWTERNYVQVNDAHRSLRYFCVWKNSNFGLRLQHDTVHLFINQTVRGMSGL
GYRNGMCQPLQSCAIITTTNKTLNKIAIAIAHHLGHNLGMTHDDAFCKCGHPKCIMHVSN
PPVTAFSNCSYSYFWSYSLQFAQCLFYKTHPKDIFSKKRCGDGIVEADEECDCGSLQSCS
TDACCLTNCTLTYGSICAFGLCCKDCQLLPPGIMCRKEVSECDLPEWCDGRSPFCPKDVY
VEDGIPCNESAYCYEKKCNNRNDQCKQIFGEDAISASPSCYNSMNTRGDRFGNCGILKST
YIKCNVSDSQCGRIQCDKVTQMPLLRDHSTVIHTHFNNVICWGIDYHFGMTIPDLGEVKD
GTECGPEHICMNRKCVHLSGLDSNCTPKFCNMRGICNNKHHCHCNSFWDPPNCLIRGNGG
SIDSGPPPKREKIKKKYLLIASLFWLLLLLCCLLCLCIRRKKKEVPAQPDKQPQMVPPPP
AKPEKKVPPPPPKPQKMIPPSPAKPPQKAPTQPAKPPQKAPTQPAKPQKKAPTQPAKPQQ
KPS

>Gallus gallus_ADAM29(ENSGALP_22413)
QSVGQRWVVTMETLLVLVVLLGLVGCPTTPDDESGPLHVTGMWVTVPRQLSPRADTNPLT
VSYWLQVEGRPQVLRLRPRKGLASRPFTLVTYDEDGARQEEQVYVQDNCFYQGEVQGSPG
SLVALGTCGRGLRGVLWMEGSTYEIEPIPDDPAFQHMLYRMEADSEPMGPTCGLTPEELQ
YQKTVLPWLQAPRTEDKYMLKDWWTHTRYVKLVVVVDNVRFVRSDRNESKVLRQVLEVVN
IGDSLYDQLSVQLFLVGLEIWTNSNPINITKSASKTLADFNRWRKSDLYPRMQHDTAHLF
AFQGFGKSLGLAYLGSICDRQWSAAVDSYTNRRLSSFIVTFVHELGHNLGMRHDERHCKC
RRKRCIMYESESDTDAFSDCSYKDYFDLLGRGGSCLYQAPALGSYYTLKHEYCGNKIVES
GEQCDCGSKSDCRRDPCCHPNCTLTAGSVCASGKCCKGCQILPAGTLCRARTGDCDLPEY
CNGTSPWCQEDLYVQDGTPCEDGAYCYKGKCSSHSKQCKHLFGRQARPAPLECFKEVNTR
GDRFGNCGSRNNIRFTKCSVENALCGRLQCENVHRLLPLQNHITVIQTPAGGKKCWGLDY
HLGVPTSDWGAVEDGTTCGSNKICIERTCTNISVLNYDCNITKCHNRGVCNNLKNCHCKY
GWAPPYCEQEGFGGSVDSGPPPSKQMFWRSRIGIIGLVSPFVLGVILAIYYKGAIGGWLM
RKRPGS

>Anolis carolinensis_ADAM29(ENSACAP_20682)
SQLLLILWNVLNEMESQTPPQGFRYASYEVTIPRKVMPRYGQQEALEVTYHLQIEGRGHM
VHLRQKKSFAPKNIPVLTYSKQGELQVDYPFIRNNCFYQGYIKGKLSSLAAISTCSGGLR
GLFQLENNTYEIEPVQASPNFQHVVYRLEEKEGDVKMKCGVTEEEQNHQESMMPNTENEL
TKSNSRSDWWAHTRYVKVAIVIEHERYLKFDKNETVIGIQVLDIVHIADAFYEPLSVKVS
VAGLEIWTEKNLIYIADSIMKTFNSFAIWRRNSLSKRLENDAAHLFVYKYFGRTLGLAPI
GTICDKTGASAVASYVDYTLLYFSVTFAHELGHILGMRHDGIYCRCNRRSCIMDEFHSNS
DMFSNCSYSDYFKLRNTDCLLIPPDHDKIYKVKYCGNRIVENGEQCDCGSKADCETDRCC
QSNCRLRSGAICAFGLCCAKCQYAPAQSICRDNTSICDLPEYCNGTSEWCPKDVYVQDGA
PCDENAYCYNGNCTTHVRQCKMIFGKKATVASESCFRNLNAEGDRFGNCGLNQGTYTRCH
SDNILCGRIQCENIRKLPSLEEHSTIIQSSIGNKECWSTDYHGGMRIADIGAVRDGTPCG
MDRMCIDRQCLDVSLLKYDCNVTECHNRGICNTQKHCHCDYGWDPPNCENKGYGGSIDSG
PPPPWNRALNNRKHNLFGFIFFLSPLVIVVVLGLFFKAQL

>Homo sapiens_ADAM30(ENST_369400)
MRSVQIFLSQCRLLLLLVPTMLLKSLGEDVIFHPEGEFDSYEVTIPEKLSFRGEVQGVVS
PVSYLLQLKGKKHVLHLWPKRLLLPRHLRVFSFTEHGELLEDHPYIPKDCNYMGSVKESL
DSKATISTCMGGLRGVFNIDAKHYQIEPLKASPSFEHVVYLLKKEQFGNQVCGLSDDEIE
WQMAPYENKARLRDFPGSYKHPKYLELILLFDQSRYRFVNNNLSQVIHDAILLTGIMDTY
FQDVRMRIHLKALEVWTDFNKIRVGYPELAEVLGRFVIYKKSVLNARLSSDWAHLYLQRK
YNDALAWSFGKVCSLEYAGSVSTLLDTNILAPATWSAHELGHAVGMSHDEQYCQCRGRLN
CIMGSGRTGFSNCSYISFFKHISSGATCLNNIPGLGYVLKRCGNKIVEDNEECDCGSTEE
CQKDRCCQSNCKLQPGANCSIGLCCHDCRFRPSGYVCRQEGNECDLAEYCDGNSSSCPND
VYKQDGTPCKYEGRCFRKGCRSRYMQCQSIFGPDAMEAPSECYDAVNLIGDQFGNCEITG
IRNFKKCESANSICGRLQCINVETIPDLPEHTTIISTHLQAENLMCWGTGYHLSMKPMGI
PDLGMINDGTSCGEGRVCFKKNCVNSSVLQFDCLPEKCNTRGVCNNRKNCHCMYGWAPPF
CEEVGYGGSIDSGPPGLLRGAIPSSIWVVSIIMFRLILLILSVVFVFFRQVIGNHLKPKQ
EKMPLSKAKTEQEESKTKTVQEESKTKTGQEESEAKTGQEESKAKTGQEESKANIESKRP
KAKSVKKQKK

>Pan troglodytes_ADAM30(ENSPTRP_60299)
MRSVQIFLSQCRLLLVLVPTMLLKSLGEDVIFHPEGEFDSYEVTIPEKLSFRGEVQGVVS
PVSYLLQLKGKKHVLHLWPKRLLLPRHLRVFSFTEHGELLEDHPYIPKDCNYMGSVKESL
DSKATISTCMGGLRGVFNIDAKHYQIEPLKASPSFEHVVYLLKKEQFGNQVCGLSDDEIE
WQMAPYENKARLRDFPGSYKHPKYLELILLFDQSRYRFVNNNLSQVIHDAILLTGIMDTY
FQDVRMRIHLKALEVWTDFNKIRVGYPELAEVLGRFVIYKKSVLNARLSSDWAHLYLQRK
YNDALAWSFGKVCSLEYAGSVSTLLDTNILAPATWSAHELGHAVGMSHDEQYCQCRGRLN
CIMGSGRTGFSNCSYISFFKHISSGATCLNNIPGLGYVLKRCGNKIVEDNEECDCGSTEE
CQKDRCCQSNCKLQPGANCSIGLCCHDCRFRPSGYVCRQEGNECDLAEYCDGNSSSCPND
VYKQDGTPCKYEGRCFRKGCRSRYMQCQSIFGPDAMEAPSECYDAVNLIGDQFGNCEITG
IRNFKKCESANSICGRLQCINVETIPDLPEHTTIISTHLQAENLMCWGTGYHLSMKPMGI
PDLGMINDGTSCGEDRVCFKKNCVNSSVLQFDCLPEKCNTRGVCNNRKNCHCMYGWAPPF
CEEVGYGGSIDSGPPGLLRGAIPSSIWVVSIIMFRLILLILSVIFVFFRQVIGNHLKPKQ
EKMPLSKAKTEQEESKTKTVQEESKTKTGQEESEAKTGQEESKAKTGQEESKANIESKRP
KAKSVKKQKK

>Mus musculus_ADAM30(ENSMUSP_60505)
MRSVWAFLPQHRWLFLTMLFHEAVGEEDLLFDPDWGFDSYEITIPKVISFKKGAQGVDSS
LSYLLQIEGKARVVHLRPKKLLLPRHLPVFSFTQEGSLIEDYPHIPDQCNYVGSVEGSQE
SESTLSTCMGGLRGVLNIDSRYYQIEPLRASSSFEHVVYLVTEDNFNNETCGVVDEETGG
QTAEEEEMARISSFHQSYKHQRYLELVMVFDLDRFVFARGNMSRMVDDAILLASIADTYF
QDVSLKIQLKALEVWTYYNRIRLYYPSLSEVLGQFVHYKRNSMHHRLPADWFHLYIARRY
IDANAWSWGRACEEFHAGSASSFLNVNILGPATWTAHELGHCVGMIHDEEFCQCRGRKSC
IMGTGRTGFSNCSYHQYFLHASYKMSYCLSDFPKLHIVERCGNKIVENKEECDCGSKEDC
KKDLCCGPDCKWKEGVNCSSGLCCHKCNFLPSGYVCRKEVNECDLEEYCDGTSGVCPDDS
YKQDGTPCRNGGFCFRKGCRSRYLQCQSIFGRKAKEAPHQCYEAVNMLGDQSGNCGIVNA
TRYTRCHRGNTICGRLQCINVKALSKFPDHTIILSTYLRGDNLICWGTSYHGTMIPHGVP
DIGDISDGTSCGRNRVCLNRTCVDYTNLKFDCLPDKCNSRGVCNNRKNCHCSYGWEPPFC
VEVGYGGSLDSGPPGPRIEVLSTTSALYMLRTILFLVSMIVVCLGQLIRNLFRNRRRNLQ
QKNPAETQGKKR

>Rattus norvegicus_ADAM30(ENSRNOP_25733)
MRSVWASLPQHRWLLLAMLFLEAMAEDLLFDPDWGFDSYEITIPKVLSLRKEAQGVDSSL
SYLLQIEGKERVVHLRPKKLLLPRHLPVFSFTQEDSLIEDYPHIPDQCNYVGFVEGSQEA
ESTLSTCMGGLRGVLNIDSRYYQIEPLRASSRFEHVVYLLTEDNFGNETCGVVDEETDGQ
TAEEEEVARIKNFHQSYKHQRYLELVMVFDLSRYVFTRGNMTRMVEDAILLASIADTYFQ
DVSLKIQLKALEVWTQFDKIHLYYSSLSQVLGQFVLYKRASLHHRLPADWAHLYIARRYS
DATAWSWGRACEEFHAGSASSFLNVNLLGPATWTAHEMGHCVGMYHDEEFCQCRGRKSCV
MGTGRTGFSNCSYHQYFLHASYKMSYCLSDFPKLHIVERCGNKIVENKEECDCGSEEECK
SDLCCGPDCKWKEGVNCSSGLCCHKCNFLPSGYVCREEENECDLAEYCDGLSGFCPKDYY
KQDGTPCRYGGFCFHKGCRSRYLQCQAIFGRRAKEAPRQCYDAVNMIGDQSGNCGIVNAT
RYTKCHRDNTICGRLQCVNIKALSRFPDHTLLLSTHLKKDNLKCWGTSYHGTMIPHGVPD
IGDVNDGTSCGPNRVCLNRTCVDYATLKFDCLPKKCNSRGVCNNKKNCHCTYGWEPPFCV
EVGYGGSIDSGPPGPRARLAKVHVLYMLRTILFIFSVIVVCFTQRMKNLFRKRQQKNPAE
TQGKKR

>Bos taurus_ADAM30(ENSBTAP_54522)
MRSVRTCLSPGRSLVLAVLLVDSLGKDLHFHPEWGFDSYEITIPKKLSFRGREQRAARHV
SYLLKVKGRNRVVHLWPKRFLLPRNLQVFSFTEQGRLLEDHPYIPSDCNYMGLVEGNPDS
QATISTCMGGLRGILKIDANHYQIEPRKASSQFEHVVYLLEKEEEFPSDFCGLTNDETVE
QMAQHENMARTPDFTESYVHQKYLELALVFDNSRYLYLNSNLTQIINDAILLTSIADSYF
QDVRMRIQLLAVEVWTDRDKIRLNFGQLSQVLGQFVKYRSRDLRVRIPADWAHLYVHKKF
KDALAHHWGSVCSMMPSGSTSSVLDRNILGPATWTAHVLGHSVGMTHDYEYCQCKGRHSC
IMGTGRTGFSNCSYAEFYSHVNSGLNCLNNLPGLGYVVKRCGNKIVEENEECDCGSGEEC
EEDGCCQPDCKFKEGANCSTGLCCHKCQFRPSGYMCRVEENECDLAEYCNGTSAFCPSDT
YKQDGTPCKYRSRCVRKGCQSRTMQCQNIFGADALGAPHQCYDAVNVIGDQYGNCGILGV
REYKKCPKERSLCGRLQCINVETLPDMPDHTILISTHLHKENLMCWGIGYHLAMVPMGLR
DLGVINDGTSCGKERVCFNRNCVNSSILNFDCFPEKCNRRGVCNSNRNCHCMYGWAPPLC
EEVGYGGSIDSGPPGPLRKNMPISLQVVILILMRLIFLIISVIVVFYRKNHRNLIQRNKA
EIEKNTR

>Monodelphis domestica_ADAM30(ENSMODP_23305)
VASGSWVPARQTRAWAMGAASLLLLGLGTLVLGKSCWSQDFDFNPDWGFTSYEVIIPRQL
EPRGGYPNRLGRVSYLMRIQGKRNIVHLRPKKLLLPRHLRVFTFADDGTRVEDQPYIPRP
CNFKGSVEGSPESEAILSTCLGGLRGMLRIEDSVYQIEPVQYSYNFEHVIYRLQDHLMNN
FTCGLTKEEIDRQLSLLRYLPADRSDSWRTSYVHQKYLELIIVLDKLRFTFLKSNLTRAI
SDSIIMGGVMDSYFQSLNARIQLIAIEVWTDKSKVNTNVKKLSQVLGEFSKYNDKILYLN
VKSDWAHLYVHKYYPDALGWAFVGGVCKRKYGVSTSTLPNKNLIAPAIWSTHEVGHGVGM
QHDGKNCFCFSKTECLMGSGGSTGFSNCSFVNYFDFINWDTASSCLNNIPGLVYTMQRCG
NKIIEKGEECDCGTIEECKKDMCCQIDCKLRPGAQCNTGLCCTNCHFSPSGHKCREEQNE
CDLAEFCNGTSNFCPTDLYKQDGTPCSRGARCYQKGCHDRFLQCKEIFGSGALNAPYLCY
KELNKLTDRFANCGLKGQSYKQCKSRDIMCGRLQCVNVKNVPDMPDHTTVIFTHVKEFNI
RCWGIDYHSSMISMALPDEGAVKDGTSCGHDLICINRSCLNVSVLKYDCLPEKCNKRGVC
NNKKNCHCNYGWAPPFCENPGFGGSINSGPRGKMKDVPKSVKVVPIIFIRLLLLGISLVM
VILKGLSRRFFKPKKIVRLSIFKKHNEKKEMAPKKHPK

>Homo sapiens_ADAM33(ENST_356518)
MGWRPRRARGTPLLLLLLLLLLWPVPGAGVLQGHIPGQPVTPHWVLDGQPWRTVSLEEPV
SKPDMGLVALEAEGQELLLELEKNHRLLAPGYIETHYGPDGQPVVLAPNHTDHCHYQGRV
RGFPDSWVVLCTCSGMSGLITLSRNASYYLRPWPPRGSKDFSTHEIFRMEQLLTWKGTCG
HRDPGNKAGMTSLPGGPQSRGRREARRTRKYLELYIVADHTLFLTRHRNLNHTKQRLLEV
ANYVDQLLRTLDIQVALTGLEVWTERDRSRVTQDANATLWAFLQWRRGLWAQRPHDSAQL
LTGRAFQGATVGLAPVEGMCRAESSGGVSTDHSELPIGAAATMAHEIGHSLGLSHDPDGC
CVEAAAESGGCVMAAATGHPFPRVFSACSRRQLRAFFRKGGGACLSNAPDPGLPVPPALC
GNGFVEAGEECDCGPGQECRDLCCFAHNCSLRPGAQCAHGDCCVRCLLKPAGALCRQAMG
DCDLPEFCTGTSSHCPPDVYLLDGSPCARGSGYCWDGACPTLEQQCQQLWGPGSHPAPEA
CFQVVNSAGDAHGNCGQDSEGHFLPCAGRDALCGKLQCQGGKPSLLAPHMVPVDSTVHLD
GQEVTCRGALALPSAQLDLLGLGLVEPGTQCGPRMVCQSRRCRKNAFQELQRCLTACHSH
GVCNSNHNCHCAPGWAPPFCDKPGFGGSMDSGPVQAENHDTFLLAMLLSVLLPLLPGAGL
AWCCYRLPGAHLQRCSWGCRRDPACSGPKDGPHRDHPLGGVHPMELGPTATGQPWPLDPE
NSHEPSSHPEKPLPAVSPDPQADQVQMPRSCLW

>Pan troglodytes_ADAM33(ENSPTRP_39913)
MGWRPRRARGTPLLLLLLLLLLWPVPSAGVLQGHIPGQPVTPHWVLDGQPWRAVSLEEPV
SKPDMGLVALEAEGQELLLELEKNHRLLAPGYIETHYSPDGQPVVLAPNHTDHCHYQGRV
RGFPDSWVVLCTCSGMSGLITLSRNASYYLRPWPPRGSKDFSTHKIFRMEQLLTWKGACG
HRDPGNKAGMTSLPGGPQSRDRREARRTRKYLELYIVADHTLFLTRHRNLNHTKQRLLEV
ANYVDQLLRTLDIQVVLAGLEVWTERDRSRVTQDANATLWAFLQWRRGLWAQRPHDSAQL
LTGRAFQGATVGLAPVEGMCRAESSGGVSTDHSELPIGAAATMAHEIGHSLGLSHDPDGC
CVEAAAESGGCVMAAATGDALCGKLQCLGGKPSLLAPHMVPVDSTVHLEGHEVTCRGALA
LPSAQLDLLGLGLVEPGTQCGPRMVCQSRRCRKNAFQELQRCLTACHSHGVCNSNHNCHC
APGWAPPFCDKPGFGGSMDSGPVQAENHDTFLLAMLLSVLLPLLPGAGLAWCCYRLPGAH
LQRCSWGCRRDPACSGPKDGPHRDHPLGGVHPMELGPTATGQPWPLDPENSHEPRSHPEK
PLPAVSPDPQADQAQMPRSCLW

>Mus musculus_ADAM33(ENSMUSP_139344)
MGSRCGRPGGSPVLLLLPLLLPSCPLRSARMFPGNAHGELVTPHWILEGRLWLKVTLEEP
ILKPDSVLVALEAEGQDLLLELEKKHKLLAPGYTETHYRPDGHPVVLSPNHTDHCQYHGR
VRGFRESWVVLSTCSGMSGLIVLSSKVSYYLQPRTPGDTKDFPTHEIFRMEQLFTWRGVQ
RDKNSQYKAGMASLPHVPQSRVRREARRSPRYLELYIVADHTLFLLQHQNLNHTRQRLLE
VANCVDQILRTLDIQLVLTGLEVWTEQDLSRITQDANETLWAFLQWRRGVWARRPHDSTQ
LLTGRTFQGTTVGLAPVEGICRAESSGGVSTDHSELPIGTAATMAHEIGHSLGLHHDPEG
CCVQADAEQGGCVMEAATGHPFPRVFSACSRRQLRTFFRKGGGPCLSNTSAPGLLVLPSR
CGNGFLEAGEECDCGSGQKCPDPCCFAHNCSLRAGAQCAHGDCCARCLLKSAGTPCRPAA
TDCDLPEFCTGTSPYCPADVYLLDGSPCAEGRGYCLDGWCPTLEQQCQQLWGPGSKPAPE
PCFQQMNSMGNSQGNCGQDHKGSFLPCAQRDALCGKLLCQGGEPNPLVPHIVTMDSTILL
EGREVVCRGAFVLPDSHLDQLDLGLVEPGTGCGPRMVCQDRHCQNATSQELERCLTACHN
GGVCNSNRNCHCAAGWAPPFCDKPGLGGSVDSGPAQSANRDAFPLAMLLSFLLPLLPGAG
LAWCYYQLPTFCHRRGLCCRRDPLWNRDIPLGSVHPVEFGSIITGEPSPPPPWTSCQQRS
HPPSLDLLSDPANSELT

>Rattus norvegicus_ADAM33(ENSRNOP_40646)
GCRCGRPGGSPMLLLLLLLLPACPLLSARMFPGNAGGELVTPHWVLDGKTWLKVTLKEQI
SKPDSGLVALKAEGQDLLLELEKNHRLLAPGYTETYYSRDGQPIVLSPNHTDHCHYQGCV
RGFRESWVVLSTCSGMSGLIVLSSKVSYYLHPWMPGDTKDFPTHKIFRVEQLFTWRGARK
DKNSQFKAGMARLPHVPHRRMRREARRSPKYLELYIVADHALFLLQRQNLNHTRQRLLEI
ANCVDQILRTLDIQLVLTGLEVWTEQDHSRITQDANETLWAFLQWRRGLWVRRPHDSTQL
LTGRTFQGTTVGLAPVEGMCHAESSGGVSTDHSELPIGTAATMAHEIGHSLGLHHDPEGC
CMEADAEQGGCVMEAATGHPFPRVFSACSRRQLRTFFRKGGGACLSNVSAPGLLVLPSRC
GNGFVEAEEECDCGSGQKRPDPCCFAHNCSLRAGAQCAQGDCCARCLLKPAGTPCRPAAN
DCDLPEFCTGTSPHCPADVYLLDGSPCAEGRGYCLDGWCPTLEKQCQQLWGPGSQPAPEP
CFQQMNSVGNSQGNCGQDSKGSFLPCTQRDAQCGKLLCQGGKPNPLVPHVVTVDSTILLK
GRQVLCRGAFVLPDTHLDQLGLGLVEPGTRCGPRMVCQERHCQNATSQELERCSSGCHNR
GVCNSNRNCHCAAGWAPPFCDKPGLGGSVDSGPAQSANPDAFPLAMLLSFLLPLLPGAGL
AWCYYQLPTLCQQPGRCCRRDALCNRDQPLGSVHPVEFGSIITGEPSPPKARDPCQQHLH
PSSLELFSDPEESELT

>Canis familiaris_ADAM33(ENSCAFP_9355)
CGPGPPRARGSRAWLLLLLFLRLPLPLRGAQAFQGNNPGEPVTLHWILDGQIRSKVTWEE
PVSKLDTGLVAVEAKGQELLLELEKNHRLLAPGYTETHYNPDGQPVVLVPNHTDHCHYHG
HVRGFPDSWVVFSTCSGMRGLITLGCNASYYVHPWSAGDSEDFITHKMFQTQQLLSWKRA
CGHRDARNKGDMASLSRATQIKERREVRKSPKFLELYIVADHTLFLTQHRNLNHTKQRLL
EVANYVDQILRTLDIQVALTGLEVWTEQDQSRVSPDANATLWAFLQWRRGLWARRPHDSA
QLLTGRAFRGATVGLAPIEGMCRAESSGGVSTDHSELPIGAAATMAHEIGHSLGLGHDPE
GCCVEAAAEQGGCVMAAATGHPFPRVFSACSRRQLRAFFRKGGGACLSNAPDSRLLVPRA
RCGNGLVEEGEECDCGASQECQDACCLAHNCSLRAGAQCSHGDCCARCLLKPAGVPCRRA
VGDCDLPEFCTGASPYCPPDIYLLDGSPCASGRGYCWDGACPTLEEQCQQLWGPGSSPAP
ELCFQIVNSAGDAHGNCGQDGKGGFVPCAPRDAQCGKLQCLGGEQHPLPPHTVPVDSSVG
LGREEVTCRGVFLLPGVQLDLLDLGLVEPGTPCGPRMVCQNRRCQNTTFLELEQCLTTCH
GHGVCNSNKNCHCAPGWAPPSCDKPGFGGSVDSGPMQPENHKTFLLGVILSFLLPLLPGA
GLAWCCCRQPRSGLQQCLWGLRRDPSCSRPKDGPNRDRPSSSIHPMELGPAATGEPQPLA
PRTLPEPRSHLEKPLPCCSACNHKVGQVQKPRSCLW

>Bos taurus_ADAM33(ENSBTAP_17511)
RAMRPGSRRARGSPTWGLLLLLGLPWPVWGTKEFQGNSLGKPVILHWSLDGRPQRMVTLE
EPVPKLQVRLVALEAEGQELLLELEKNHRLLAPGYTETHYSPDGRPVVLFPNHKDHCHYH
GHVRGFLDSWVILSICSGMRGLITLSSNASYYVHPSPAGDSKDFLTHRIFRVEQLFRGKG
TCGHRDPKDKRDTISLSCATQIRERRESLRSPRYLELYIVGDHTLFLTQHRNLNHAKQRL
LEIANYVDQILRTLDIKVVLTGLEVWTEQDQSRVTPDANATLWAFLQWRRGLWARQPHDS
AQLLTGQAFRGATVGLAPVEGMCLAESSGGVTTDHSEFSIGAAATMAHEIGHSLGLSHDP
HGCCAEAAVEQGGCVMAAATGHPFPRVFSACSRRQLRAFFRKGRGACLSNAPDSGLLVPQ
ARCGNGFVEKGEECDCGAGQECPDSCCLAHNCSLRAGAQCTHGDCCAHCLLKPAGTPCRP
AAGDCDLPEFCTGASPYCPPDIYLLDGSPCARGRGYCRDGACPTLEQQCQQLWGPGSRPA
PEACFQVVNSAGDAQGNCGQQGDGNFVPCARRDAQCGKLQCQGGEQSALVPHVVPVDSTV
HLGSREVTCRGASMLPGAQLDLPDLGLVEAGTQCGPRMVCQERRCQNTTFRELELCLMAC
HGRGVCNSNRNCHCAPGWAPPSCDKPGLGGSVDSGPVRPQNPDAFTLAMILSSVLPLLPG
AGLAWCCYRRPGLCLQQCFWGSRRALMCSGSKDGPCRGHPLGSIHPVELRLTAPQESQPL
EPNSHLEKPASHSPACTPKVGRVQKPRSCLW

>Monodelphis domestica_ADAM33(ENSMODP_5730)
MGWGSDGASGSQGPGTARWTPRLLLLLLLPPLGTGTRAREPRGPPFGEPVTPHWVLSSRS
RREITTEETVRSPDEALLSVRAEGKELLLSLQKNRWLLAQGYTETHYGPDGKAVTLAPNH
TDHCYYHGHVQGFPDSWVALSSCSGISGLIVLSANRSYYVQPPRTSVSGPPGPHRLFRTE
QLPRKDGICSHGLPGSLSLASLLHRHQAHRVRRDSRRALKYLELFIVADHALYLRQQRDL
GRTKQRLLEIANYVDKFYRSLNIKVALTGLEVWTERDQSRVTGDANATLWAFLQWRRGLR
SRRPHDTAQLLTGRTFQGTTIGMAPLEGMCSADNSGGVSADHSELPIGAAATMAHEIGHS
FGMSHDADGCCEEALPEEGGCVMAAATGHPFPQVFSSCSRQQLLTFFQKGGGMCLFNPPD
PRLLVLGVRCGNGFLEDGEECDCGDIEECTDPCCHAHNCTLREGAQCAQGDCCAHCSLKP
AGTLCREGAGDCDLPEFCTGASPHCPANVYLLDGSPCAGGTAYCRDGMCPTHEGQCQQLW
GPGAHPAPDACFQDVNSAGDRYGNCGQDSEGHYVPCDRRDAKCGKLQCQSGADKPRGPHT
VSMETTIRLGGREVKCRGAFMYRVTRPDSSADLPDPGLVLPGTKCGDGMVCHDRRCQNAS
FPELQRCLDTCHGHGVCNSNKNCHCDAGWAPPTCEKPGLGGSVDSGPVQYDNQDATLLAL
LLVFILLLLPSAGVALYYYRSPNSLLYQSLRGLRKGQESCRHRSKAIKNSRSGAQSGLTL
QNLPLRQPLRPAPGVSPQGVRGPLSPKPGPSQTGSQPVNVVRPLRPGPSKPRDSRPARPP
PPLSHSPRPGFPRKDPGDRGDRADGTGRLLPPKRPLPVNPARGPKDPLKKDPLKKDPPSR
PLPGDPVLVKQPLRGPRLLVMVPPSPARSPRPGPGRGSLTLKK

>Danio rerio_ADAM33(ENSDARP_77690)
MYTKHRQKSGHISSTRYVLVMLSVFLFNGLLEYVGGNPREEDRGQRVTVHWISHSTAQQE
PETTFKDKFPESGEILVSAQDLELVLQVERNQELLGHDFTETHYENGLPITQSSHHTDHC
FYHGRVRGHADSWVALSTCLGMRGLIVLNSNDTFYLEPIRGQEVVHHAFYRTEDLPIKSG
TCGHSHHTGQMSLFSGDFKPLHQRVRRNAWGTTKYMELYIVADNTLYRKQNKDLDKTKLR
IMEIANYVDKFYRELNIRVPLIGLEVWTEHDQCIINEEPNSTLWSFLQWRQKLKSRKKHD
NAQLLTGVIFKGTTIGMAPLEGMCSHENSGGINVDHSELPIGAAATMAHEIGHNFGMSHD
HEGCCVEATAEQGGCVMAAATGHPFPKVFSRCSKKDLDNYFQKGGGMCLFNMPNMKDLVG
GKRCGNGFVEEGEECDCGEPEECTNDCCHPSNCTLKVDAQCAHGVCCEGCKLKQAGTMCR
GPAGACDLPEYCTGGSPYCPSNVYLLDGSSCQYGRAYCYNGMCLTHEQQCLQLWGYGAQP
AHDACFQDVNAAGNAFGNCGKDSKGNYMKCEKSDAKCGKIQCHSAAKKPKGTNAVSIDTT
IQTDGIEVKCRGTFVYSTQDGQGDLPDPGLVMTGTKCGEGKVCKDRRCQNTSFTELESCI
VRCHGHGVCNSNGNCHCSRGWAPPFCEKPGLGGSVDSGPVQYDSQVGLVVGLLFAFLVLL
PAVLIAFYCVKIKSSYYHKWRKQREKSKASRHDTSTEKGKNGHLNPAFHLKVVGPNNRNA
NIKLPHTSKEVLPLRPNPATNGPQPVNIVRPLRPAPSPSLSNMKGPRPPPPISKPPNSPK
TPKTVASPQKLSPPKKPLPLNPSRTPLMVSQQQPRPPSTPPQRPLPLSPARGAQPRSSSG
GLMVMMPPAVGPKPVGKVTAVPPLKAFQPASGPKPLIVPAVFRK

>Branchiostoma floridae_(XP_002603851)
MESRAETKYVELIMVADNMEKYESNRQAVLDRLQEAANIADSIYKTINMRVALMGIEVWTSGNPIDVTAV
ASETMYRFLDWRRDNLLPDNPDNDNAQLITGITFQGSTVGMAPLSSMCSSGRSGGVDEDHGIHAAAVAST
MAHEMGHNLGMNHDTSDRGCACSASYQEGGCVMEPAAGWPAAVFSSCSSTDLQNALLKGVGACLYNLPDP
DQLYGGPVCGNGYLEEGEDCDCGTVDECTSPCCDPSTCTLHENATCAIGLCCEGCQLVSAGTLCRDDLGD
CDLPEYCTGTSPHCPPNVFIQDGYDCLYEEGYCFNGACLTHEAQCKETWGEGKKVAEDVCYSLINTKGDV
YGNCGKDENDQYIPCSEM

>Branchiostoma floridae_(XP_002606207)
EHCYYHGRIRGRPGSTVALSTCNGLLGMFDDGDSLYFIRPSDDQDVVPEKPTRTIIFSLVASCFLAGCSS
LAGLPLFVPFPSDLWSLIQTSTRLKRDVLPETKYIELILVNDNRMFQMYKNNSQRTSSVAKTVANLVDAM
YSKQLNTRIALVAIETWDSEDQIAVNSDAQETLRQFLKYRYRNLLNWQSHDAAHLLSGMAFADGVTGQAP
INGICTKRNSGGVNENPRNAVVLAVTLAHQLGHNLGMHDDNGRDCFKACPDWYGCIMEKERGIQQPRRFS
QCSVRDYRQLLMNGLGACIFNRPQKLHEPPYCGNGFIEKGEQCDCGPPTYYRRCVKCCDNCMLTEEAQCA
HGECCDLSTCKYKEGDTACRAPVNACDLEEKCTGRSGECPDNLYKQDGQLCEVDGHCYYGECRTRTNQCK
YVWGEDVYTADDVCYQRLNINGNRDGNCGKSEDGGWDKCEPKDIFCGYLLCDGNVTVPRVGVLDGSLTSK
SYPRTGKTMHCKGGHVLLDDSNNIGYVQDGTTCGTNKMCHSGRCVEVSSFNITPCPVGVNGLPCSGHGNC
TNEDRCLCDTKEWRGRDCACSPPVPTPVPPGTTNAIIGSMAGTLLAIAIVFGGLGWGFQ

>Strongylocentrotus purpuratus_(NP_999635)
MDGIKPLYKGFQAVIFVLVGILFITDHCLGYRTPGGQEEQLGKLLNYDIVTPYRLAGRERRQAHTITQDG
HMRETSFVLSAFGKQFTLDVRLNEDLFPARYIERSYAQDGGAITRKPHPHHHCYYHGEVREANTSSVALS
TCNGISGVFMADGESYYIELLLEADEQHLVYRPQDRRDKKTWVFDVDSSHHEQSEQEAEEPTLGHRTRRD
VHSETKFIELVIVNDYQEFLRQEENETIVAGRSKEIANVMDMIYRPMNVRVALVGVVTWSQGDRFVVSSL
QGNTMGEFQRWRNNELLPDIKNDNAQFITGVSFDGSTVGMASLGTMCSDERSGGVSQDHDRNAAVVASTV
AHEMGHNLGFMHDTSDRNCVCDAPSNVGCVMEPSSGPIPPTNFSTCSYTDLKTSLEKGLGACLFDYPDMI
FDGPICGNGFLEVGEECDCGTVEECSNDCCIPATCRLHENATCAVGECCEDCQLKKAGEVCRDLSNMCDL
PEYCTGLSAECPANVYRQNGQTCANMDDSTCYDGQCLAFDDQCEKIWGPGAEVAHENCFNFNTQGSSFGN
CGGTSSSFQACERSHVKCGKLMCVGGSSYPILSSLAKASQGYIWDENNNQHTCKSASIDLGQDVPDPGYV
ATGSQCAPGFVCSDFQCQNLSSLNIRACPHNCNDHGVCNSKNHCHCDPQWSPPLCNTRGYGGSIDSGPAR
ATDQPGGPGSNMVIVLLVMFLCVLPGLALIGILVYCKRQTLSKMVSKSKGTTKQTYPSSTNNYRNQESRP
APGPARHAPVKPAIQHTYLQETSNVFKFPASGAPPAAPQAAMRPARTAPAPLRSQETPIVHRPAPPVSQA
KKPTASIAPLKVETAPKPSRPPVPLNKPPSPAKSPPSVSVPVPKGIRVAPKPPSVHSSAKPQFRLPPPIE
ASTTKPANAPPGLPTKPALKPTVPKVPLRPTPVTRPKPNVNRNNSTELDESSNFSPTNKVSEPFAAEKSI
PVADKPLVALKPVPPKKPAVPNKPTVPTRPPALKPPVKKDPVV

>Drosophila melanogaster_(FBpp0300197)
MWINIANLILIIAQLCVFVTSAGEADYTLDDSFWNEESPVGEVERLLKEYRQNQELVRRI
GGHYYQIIYPVQLRHHEKMGISTREVSLPKPGQRPRPHDDSGFNRGRTKKHFHRTSLLIK
AFNHKFRLDLELNSQLLSPNIQQKHYHVGGYLVDGNRHDIEHCYYHGTVKDYPGASAAFH
TCNGVSGVIHIGNETFVIHPFYGGDLSKHPHVIFEARTKANKGCANSGNLDSWRLSRRTK
HLSAGVAGVVEEILQAGVGRNKRDVREATKYIETAIIVDKAMFDKRNGSTRAEVIHDAIQ
VANIADLYFRTLNTRVSVVYIETWGKNQAVIDGSKDISKAISNFNDYTSRNLFQIERDTT
QLLTGETFAGGEAGMAVPETVCTPRAVGISVDVNVYEPHLLAGTMAHMIGHNIGMGHDDG
REECFCRDWHGCIMAQSIVGQENVQPYKFSECSKKDYIDALRTGHGLCLLNKPNEIELRR
NCGNKVVEEDEECDCGTFEECALDQCCDGITCKLKSEAQCASGACCDQCRLRPKDYICRD
SNNECDLPEYCDGEIGQCPSDVFKKNGSPCGLSKTGISGYCFQGYCPTLSLQCEAIWGYG
GSAADRQCYEQFNSKGSINGHCGRDANEHYIKCEPENVQCGTLQCKDGERQPVNDGIDQL
YSRTIISIKGQEFECKATSGQVGSNSYPEHGLVKDGTPCGDNLICLNQTCVSLFPHVDQT
KCPANSQGLECSEHGVCTNTNRCFCDMGWGGNDCSSVVLLTTALPTEALPTPENTIKMEK
KETPYENYHGSNTVFLVGVLMSVVGFVFITFTLMALCYRRKTTTLKYDPPYSKKPIAKSY
GGAATAPNHHSVEEVSLDGSSKLVYANQTGFRDKGIHGRRYTTCGEDDQSHAEKGILKKH
GYGLVHGEQLKDKWGDDNQSDNLELITQDGTLASTSGGAAASEVERTLKSLNGYHEDILE
ALRNAATHRGTGTGNTPVGSGSLSEEMLRKTLQDCNNSQLGYSAEQYKRNIGSKSSSREN
ICDNAAVHAIILDGSGGGLGGMGLGSSVGAGGGSTSMSGGMPGHGGTMLHHHRSQHQLHQ
PSTVALQPQQLDDDDAPSTGPLRIRNLEDLIRQLEHHSSRHMSPSGSEDIRMSETEADRH
YRLESSAACSESSQGSNQQIPQSQKTATIHASYSRSCRPRSDEESRFTFGGRYRQPASSG
RHAPHQSHSPHAFGHHTHHSHAHGHATHGPHSSHHSSHTHLQQEDEGIYETADHHERQVV
DARLDCHETPDSESDDFIQAQQQLARWASEDVVSVVVLDQPPSGTMSDSQPYIDVGPISG
AIAQQQHPHQQQQQQQQQQHPHQHHGDHHQSSAAAAGSGSGVAAATSVANSSIMALPIVP
NGISVSQRDYYPSPPSTETESSGSVIQPPIRRGLQSAAAAAAAADTAALSQHQQQLQLLQ
LPIYQQHPHQHHHPQQSGDTSSSNNSQSEQIIENGCYPEYKH

>Drosophila melanogaster_(FBpp0290713)
MLHLHLFLLPLLLLNTCLQQHILQPAEATAFHQSEGEKSKAHPVLEEFSTYTVIRPQVEH
GRTKRSLLTTLDATDGLHTPQISLSYTHEGKRVVVDLQRNDLLLPNSHFLRYQNASRGAT
PGHVVTTFTKTEVDLCHYQGHIRGKPESVVALSTCDGALDGIVIDGRQTYFIHPHIDGRG
RLQDDHYLLKQADMHPTNATCGYDNHRDDHSHDYEKADGDNGLGGGIPSLPLRLDGGEFS
RTLLRKRRQADDSSQLIRGPYNANKYSSYVELVIVVDNKVYKNFQENTKKVHQYCKGIAN
IINALYVPLNIFVALVGVVIWNESNEIEFSSDGDLTLRNFLNYRSTKLVLDHPNDNAQLL
TKENFAGGVVGKALKGPICTYEYSGGVSMQHSPNPAMVATTMAHEMGHNFGMEHDTSDCH
CRDEKCVMAASSTSFIPVNWSSCSIDQLTIAFSRGMNYCLRNKPERLFESPTCGNGFVEP
GEQCDCGLPEHCENACCNAQTCMLHSKNATCATGECCDLTTCRPKLAGSACREAENECDL
PEYCTGESEYCPADVFRRDTEPCDGGQAYCFHGTCRSHSNQCRTLWGPTGDNSEHCYNKN
TEGTRLGNCGYNRLNKTFLRCEEQHVNCGMLHCIHLNERLEFGMESAAVLSHSYISHDRK
IVACRTALVDLGLQTTDPGLTPNGAKCGVDKMCVDQRCLPVDAVRQKGMGKPCPEDCNGN
GICNSRGHCHCDVGFGGESCSKAGSGGSPDSGPATDPNGSVGFKRFLYVLFFFVLPVVAL
FWFLYHCYKNGMLTRGKLADNILKSSGGSKPITTRTNQNGTGPPPSNGLLKSTPSSTDDM
DSALLKSPSDSTPSAGLFGKFDGFTLRPLNDASSPASNYNGPNVAFVQPTVQQDGPQRMA
PPPPVVKPGTAPIHPPSPKPEATWVRPAPALPPPNPGSTARPIISPPKLDSSTLTMVPLK
DSTEDLSPSRSAPPVPLHADPKLNVKRDGTIRRFASFLKKEEKPPLKEKTYIDRERLRTL
EISAPMPVPAAPQAESSNSDSETTPREEETQNLVKRAQSMRSPTKKAPLQSFGSMRSPPG
LPRPKSGQVNSNGASRPKSPPPRPPPVVVKKTNSISSSGYQRPVSTAQRSVENTYDDCEF
VENEVRASNDDIYSVIDEIPPAAQTLKRSDLVANRASNGSDMGLLNEIVNELEKINGDSI
YSGKPVAAAASAAQPTPADPPKSPQRPAPPKPASSVLEEKAANASASTYHRPPPANAPVA
RVKPTVADKSQAQAQAQPSMSSFKPAAGGNVGQSQPAPVVQLAKRSSSGSMSGVTNYARP
KSFMKSTTKTLPNGTAGASTTAPSATIQKPKPLSAKPSFSGGGAGGVLGKRANGGAAPTP
PTVKAATLAAAPKSNIASLTQRFEQSK

>Apis mellifera_(XP_006564725)
MFWLHCGLFVLVIAVPGFISSADSTSKREADYTLDDSFWNEETSVGEAERLLQEYRQNQELVQNIGAHYY
QIIYPVQLRHHEKMGISTREVSVSKFPQRGYGEGGYQNVKGRMRTGRHFHRTSLLIKAFNHKFRLDLELN
TQLLAPNLVQKDFLTVGAEQTSKQEIEHCYYHGTVRDYPGASAAFHTCNGVSGVIHLGNETFVIHPFYGG
DLSQKHPHVIFEARTKANKGCANSGNLEWRVKNRRQKHVLGLSETTSDRYKRDVRETTKYIETAIIIDKA
MFEKRNGSTRAEVVHDAIQVANIADMYFRTLNTRVSVIYIETWQGINQAEIATGMDIDLALLNLNDYMMR
TMFRVPRDTTQLLTGETFAGGESGVAIPSTICKQKSVGISVDLNTYEPHLLAGTMAHMIGHNIGMSHDDG
RSECICREWHGCIMAQSIVGLENVQPYTFSECSKTDYIEVLRSGNGFCLLNKPNEVEVRRSCGNRVIDEG
EQCDCGSIEECHEYDPCCDPITCRLTSEAQCATGPCCSDCKLLARGVVCRESTNECDLPEVCTGETGQCP
TDVYKKNGNPCSNNDGYCYNGVCPALNLQCEQIWGYGGVAADQQCFEQFNSKGSLSGHCGTDSSGHYIKC
ELENVRCGSLQCQQGRKLPTVAGIDHSRTIISIKGEEYECKSTTGKVEGSEMPGMGLVRDGTSCGDNLIC
VNQTCMSLYPLIGNERCPSNHNNHECSGNGVCTNLNNCYCNLGWSGPDCSIEQDIPTRPPITSSTEAAGK
NGTDTKLVKKETPYETTNNTLSTGTMVLILVGVVKGVFICFALMAVCYRKSTVQKYDQPYVKKPPQRGYS
GVSGNHHPGHAVLDNVNNKILTFSSMPNCREHKSQVKRPGMSEEDGDTGADEVVSFIDLPNNLTKLPEKG
ILKKHGGYGMGGGAVASVERTLDQLNGYHEHIIEALRMAANQRETSGTTSAPMDDEALTEPLTELLTEPL
PECYPTDSYRKDIIKHIDNQADEEYEEYVPSCGVIRIRNLEDLIKQLERHSARNRSPSGSEDMRMSESEA
DRPYRKDSSVCSESSQGSRRCSRGRDDTYGRYCQPSSRSPYGTHQHTQHSHQMYKEEGIYATADPDRGSN
TRGETPDSESDAFIQAQQLARRTSEDGVQHRPPQQPPPPPPPPPPAMTGSTVQLLQLHHSQREHRQQPQQ
QHHCHHHAQQSQPQQQQQPQPSSQQQHQRQQQQQQQQQQQQQQQQQQQHQLPVEQLPIQQRGYYPSPPYT
DNGLENDETENAQSHQQQKLPDVRGIDVNHLPNINKCPLDDNFSLDCNINNGSPKELNTNNTSDNENTAL
LPPSHFPEYKH

>Apis mellifera_(XP_006563556)
MPLNIFIALVGVQVWSDADEIALSPNGDTTLSNFLRYRREKLVQDMPNDNAQLLTRITFEGGVVGKALKG
PICTYEFSGGVSMDHSNVVGLVAATVAHEMGHNFGMEHDSADCDCPEEKCIMASSSGSSGPIHWSTCSLE
HLALAFEHGMDYCLRNKPQKLFDSPICGNGFVEPGEQCDCGLKENCDNPCCNVTTCMLHGNASCATGECC
DLKTCRPKSAGTECRSAEHECDLPEYCTGQSEYCPVDVFKMDGESCSMGKAFCYQGSCRTHNDQCKLLWG
PTGTSSDAQCYEMNTKGTKHGNCGYNRVESSYVKCTGENLLCGMLHCKHLNERLEFGMESVAILSHSFIN
NGGKIIPCRSAIVDLGLNQVDPGLAPDGAKCAPGKMCVNQKCMPVADLRASVSGGKACPNNCGGNGVCNS
LGHCHCNRGFRPPDCTQPGVGGSEDSGPAEDPNARNDFIMALYIIFLGIVPTIALSSFGIWYVRNSGQNW
KKSMISTTDRGHNGLSIKTIDRSSPLPRTIETIDSSLSQDPACASLLPKPDTDERYNNNLFGQFKGFTIT
PIRKQAKSLEPTKPAPPPPTIPTVAIKTNIKPIHPKSNPSRASLLNPTPPPPASTTATATTTMTTTSFDE
AAPSLPPLNPGCTARPLISSPVLAATTCTSVELSAKLVNTSDGPTRPAPAPPLLDPSQKPQRPSSTPLAN
VLAEGERKGGTLNRIASMLRPGSGGLARGGGGLGASQASQRDAERGASNSLPRSHHLKASKVMDKEILRS
LEISNPIPQREIEIPTPSIPVIPEGGEQRKASGGVVLRAQSMRDSKVTPRPAIQTFGSMRHANAAAVKRP
TSIPASARPTTAPPPVPPSTDAKGAGSEGGAKIPGLPGYQNPRVKGGQQRVAGAAGLDNAYDDCMNLVAE
PPLTKIAEESPTSSDNIYAVIEEALPEKGRRGGEGRVNEYKLPKRVEAVASEPMGLLSEIVSEISNRNFD
SIYSTASLSRKVEEEEEEDREERSKSGEGGYNNGSFGGYMNSSHYKSPGSSIYSNSPSAKFNSSSSTTSS
GYLNPSALNVPRQQGDDKSASSTSNLNEEISKELGMKGGEDGRKSAGKRSFGSQRGVAREEEGAPKAGLG
RTKTPPGLGKGQSAASNASRPKVQCSDGGSKAGGCGRQGADAEGAKAQPSDSPARQDTARANNRLSLKTV
PCSPKDNGGKLNSPDLVSSCSNSNQISTKSPDVVNGNNPKVNLQPKNVQKTPTLSRGGSGAKAPATPVKP
LNIASKGGGLAEKRKSPTGGANPIKSLPAKESGNSKVVPQAKACLGGQKAEAKGGEKTNPVQRAASGKSN
VASLQQKFEANKNANAAASRTIPSVHKAQRTVGKTTETASVKK