>Homo sapiens_HDAC4(ENSP_264606)
MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLP
VAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
MKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFP
LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGP
SSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPA
TGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLL
EQPPAQAPLVTGLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQALQHL
VIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQALLDEPY
LDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQALLLEQQ
RIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTGLVYDT
LMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVHSEAHT
LLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAVGCVVE
LVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKILIVDWD
VHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFTGGLDP
PMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGYLTKQL
MGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVRSMEKV
MEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDEEPMEE
EPPL

>Mus musculus_HDAC4(ENSMUSP_8995)
MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPTAVPMDLRLDHQFSLP
LEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLAM
KHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVLN
KKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSASYNHPVLGMYDAKDDFPL
RKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVATALKKRPLDVTDSACSSAPGSGPS
SPNSSSGNVSTENGIAPTVPSAPAETSLAHRLVTREGSVAPLPLYTSPSLPNITLGLPAT
GPAAGAAGQQDAERLALPALQQRILFPGTHLTPYLSTSPLERDGAAAHNPLLQHMVLLEQ
PPTQTPLVTGLGALPLHSQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQALQHLVI
QQQHQQFLEKHKQQFQQQQLHLSKIISKPSEPPRQPESHPEETEEELREHQALLDEPYLD
RLPGQKEPSLAGVQVKQEPIESEEEEAEATRETEPGQRPATEQELLFRQQALLLEQQRIH
QLRNYQASMEAAGIPVSFGSHRPLSRAQSSPASATFPMSVQEPPTKPRFTTGLVYDTLML
KHQCTCGNTNSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVHSEAHTLLY
GTNPLNRQKLDSSLTSVFVRLPCGGVGVDSDTIWNEVHSSGAARLAVGCVVELVFKVATG
ELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLNVSKILIVDWDVHHGNGTQ
QAFYNDPNVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFTGGLEPPMGDAEYL
AAFRTVVMPIANEFAPDVVLVSSGFDAVEGHPTPLGGYNLSAKCFGYLTKQLMGLAGGRL
VLALEGGHDLTAICDASEACVSALLGNELEPLPEKVLHQRPNANAVHSMEKVMDIHSKYW
RCLQRLSSTVGHSLIEAQKCEKEEAETVTAMASLSVGVKPAEKRSEEEPMEEEPPL

>Bos taurus_HDAC4(ENSBTAP_23621)
ASVPPFLSRKTQHSSLDQSSPPQSGASASYNHPVLGMYDAKDDFPLRKTASEPNLKLRSR
LKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSAPSSPNNSSGNVSTENG
IAPAVPSIPAETSLAHRLVAREGSVGPLPLYTSPSLPNITLGLPATGPSTGAAGQQEAER
LALPALQQRISLFPGTHLAPYLGAAPLERDAGAAPGSLLQHVVLLEQPPTQTPLVTGLGA
LPLHAQPLVGAERVAPSVHKLRQHRPLGRTQSAPLPQSTQALQHLVIQQQHQQFLEKHKQ
HFQQPQLHLNKMIPKPSEPARQPESHPEETEEELREHQALLEEPFLDRLPGQKEAHTLAG
VQVKQEPIESDDEETEPPREAEPGQRPPTEQELLFRQQALLLEQQRIHQLRNYQASMEAA
GIPVSFGGHRPLSRAQSSPASATFPMSVQEPPAKPRFTTGLVYDTLMLKHQCTCGNTNSH
PEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVHSETHALLYGTNPLNRQKLDS
KKLLGSLTSVFVRLPCGGVGVDSDTIWNEVHSSGAARLAVGCVVELVFKVATGELKNGFA
VVRPPGHHAEESTPMGFCYFNSVAIAAKLLQQRLSVSKTLVVDWDVHHGNGTQQAFYSDP
RVLYISLHRYDDGNFFPGSGAPDEVGTGAGVGFNVNMAFTGGLDPPMGDAEYLAAFRTVV
MPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSAKCFGYLTKQLMGLAGGRVVLALEGG
HDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVRSMEKVIEIHSQYWRSLQRLA
STAGYSLVEAQKCENEEAETVTAMASLSVAVKAPEKSPSPRARRGEPQP

>Canis familiaris_HDAC4(ENSCAFP_18541)
RPGHPSQWCRGGRGRGSPCRCSDRRFCAVLSPTVDVASALPLQVAPPAVPMDLRLDHQFA
LPVAEPTLREQQLQQELLALKQKQQLQRQILIAEFQRQHEQLSRQHEAQLHEHIKAGQIK
SMKVILRCPVATLKQSRKAQAYRSKDSFHALHRRREGEQLKNKEKGKESAVASTEVKMKL
QEFVLNKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSASYNHPVLGMYDT
KDDFPLRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSA
PGSAPSSPNNSSGNVSAENGITPAVASIPAETGLAHRLVTREGSVAPLPLYTSPSLPNIT
LGLPATGPSAGAAGQQDAERLALPALQQRIPLFPGTHLTPYLSTAPLERDGGAAHNPLLQ
HMVLLEQTPAQTPLVTGLGALPLHAQPLVGADRVSPSMHKLRQHRPLGRTQSAPLPQNAP
ALQHLVIIQASLKPQRAPEGLRAWRTESRAAGRIIPKQNEPARQPESHPEETEEELREHQ
ALLEEPYLDRLSGQKEAHALAGVQVKQEPIESDDEEAEPPREVEPGQRQPTEQELLFRQQ
ALLLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPMSVQEPPTKPEVH
HRGLVYDTLMLKHQCTCGNTNSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQ
TVHSEAHTLLYGTNPLNRQKLDSKKLLGSLTSVFVRLPCGGVGVDSDTIWNEVHSSGAAR
LAVGCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAIAAKLLQQRLDVS
KTLIVDWDVHHGNGTQQAFYNDPNVLYISLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNM
AFTGGLDPPMGDAEYLAAFRTVVMPIANEFAPDVVLVSSGFDAVEGHPTPLGGYNLSAKC
FGYLTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNAN
AVRSMEKVIEIHKRQFWRYLPYLCYTVGSLLDAQKCENEEAADCHPPIVSLFEGVKTAEK
RRPDEEPMEEEPPL

>Ornithorhynchus anatinus_HDAC4(ENSOANP_20481)
AASSSHPEGLFYVEIVVQSPDLAFVFAPPITVDVTTALPLQVAPSSVPMDLRLDHQFSMP
GSEPTLREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
MKHQQELLEHQRKLEQHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSATYNHPVLGMYDSKDDFP
LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACNSAPGSGP
SSPNNSSNNISNENGIAAQMTPAPQVTSLAHRLVNREGSVTQLPLYTSPSLPNITLGLPA
TGPSSGGSGQQEAERLAIPTLQQRISLFPGTHLTPYLSTTTLERDGGTAHNPLLQHMVLL
EQPAAQTPLVTGLGALPLHAQTLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQALQQL
VIQQQHQQFLEKHKQQFQQQQLHINKMIPKANEPSRQHESHPEETEEELREHQALLEEPY
SDRIPNQKEAQALASMVQVKQEPIESDEEDTELPQEVEQGQRQAEQELLFRQQALLLEQQ
RIHQLRNYQASMEAAGIPVSFGSHRPLSRAQSSPASATFPMSVQEPPTKPRFTTGLVYDT
LMLKHQCTCGNTNSHPEHAGRIQSVWSRLQETGLRGKCECIRGRKATLEELQTVHSEAHT
LLYGTNPLNRQKLDSSLTSVFVRLPCGGVGVDSDTIWNEVHSSGAARLAVGCVVELVFKV
ATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAIAAKLLQQRLNVSKILIVDWDVHHGN
GTQQAFYNDPNVLYISLHRYDDGNFFPGSGSPDEVGTGPGVGFNVNMAFTGGLDPPMGDA
EYLTAFRTVVMPIANEFAPDVVLVSSGFDAVEGHPTPLGGYNLSAKCFGYLTKQLMGLAG
GRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRSNENAVHSMEKVIEIHS
KYWRSLQRFSSTVGYSLIEAQKCENEEAETVTAMASLSVGVKQAEKRPDEEPMEEEPPL

>Gallus gallus_HDAC4(ENSGALP_33098)
PSAVDVSTALPLQVAPTSVPMDLRLDHQFPMPVTEPTLREQQLQQELLALKQKQQIQRQI
LIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLAMKHQQELLEHQRKLEQHRQEQELEKQHR
EQKLQQLKNKEKGKESAVASTEVKMKLQEFVLNKKKALAHRNLNHCISSDPRFWYGKTQH
SSLDQSSPPQSGVSGTYNHPVLGMYDSKDDFPLRKTASEPNLKLRSRLKQKVAERRSSPL
LRRKDGPVVTALKKRPLDVTDSACNSAPGSGPSSPNNSSNNISAENGITGSVTSIQAETS
LAHRLVNREGSVTQLPLYTSPSLPNITLGLPATGPSSGGSAQQDAERLAIPALQQRISLF
PGTHLTPYLSTTTLERDGGTAHNPLLQHMVLLEQPTAQTPLVTDWYLSGLPLHAQSLVGG
ERVSPSIHKLRQHRPLGRTQSAPLPQNAQALQQLVIQQQHQQFLEKHKQQFQQQQLHINK
IISKPNEPARQHESHPEETEEELREHQALLEEPYSDRVSSQKEVPGLANMVQVKQEPIES
DEEEAEPQQELESGQRQAEQELLFRQQALLLEQQRIHQLRNYQASLEAAGMPVSFGGHRP
LSRAQSSPASATFPMSVQEPPTKPRFTTGLVYDTLMLKHQCTCGNTNSHPEHAGRIQSIW
SRLQETGLRGKCECIRGRKATLEELQTVHSEAHTLLYGTNPLNRQKLDSKKLLVVGSISI
IYSQHDCLGGVNVVDSDTIWNEVHSSGAARLAVGCVIELVFKVATGELKNGFAVVRPPGH
HAEESTPMGFCYFNSVAIAAKLLQQRLNVSKILIVDWDVHHGNGTQQAFYNDPNVLYISL
HRYDDGNFFPGSGAPDEVGTGAGVGFNVNMAFTGGLDPPMGDTEYLTAFRTVVMPIANEF
APDVVLVSSGFDAVEGHPTPLGGYNLSAKCFGYLTKQLMGLAGGRVVLALEGGHDLTAIC
DASEACVSALLGNELDPLPEKVLQQRANANAVHSMEKVIEIHSKYWHSLQRYASTVGYSL
VEAQKCENEEAETVTAMASLSVGVKPAEKRPDDEPMEEEPPL

>Taeniopygia guttata_HDAC4(ENSTGUP_3338)
FSPLFPDGLSGRDQPVELLNPPRVNHMPSSVDVSTALPLQVAPSSVPMDLRLDHQFSMPV
TEPTLREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLAM
KHQQELLEHQRKLEQHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVLN
KKKALAHRNLNHCISSDPRFWYGKTQHSSLDQSSPPQSGVSGTYNHPVLGMYDSKDDFPL
RKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTGTADSACNSAPGS
GPSSPNNSSNNISTENGIAGSVTSIQAETSLAHRLVNREGSVTQLPLYTSPSLPNITLGL
PATGPSSAGQAQQDAERLAIPALQQRISLFPGTHLTPYLSTTALERDGGTAHNPLLQHMV
LLEQPTAQTPLVTDWYLSGLPLHAQPLVGGERVSPSIHKLRQHRPLGRTQSAPLPQNAQA
LQQLVIQQQHQQFLEKHKQQFQQQQLHINKIISKPPEPARQHESHPEETEEELREHQALL
EEPYGERATGQKEPPALASVVQVKQEPIESDEEEAEPQQELESGQRQAEQELLFRQQALL
LEQQRIHQLRNYQASLEAAGMPVSFGGHRPLSRAQSSPASATFPMSVQEPPTKPRFTTGL
VYDTLMLKHQCTCGNTNSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVHS
EAHTLLYGTNPLNRQKLDSKKLLGSLTSMFVRLPCGGVGVDSDTIWNEVHSSGAARLAVG
CVIELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAIAAKLLQQRLNVSKILI
VDWDVHHGNGTQQAFYNDPNVLYISLHRYDDGNFFPGSGAPDEVGTGAGVGFNVNMAFTG
GLDPPMGDTEYLTAFRTVVMPIANEFAPDVVLVSSGFDAVEGHPTPLGGYNLSAKCFGYL
TKQLMGLAGGRVVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVFQQRANANAVHS
MEKVIEIHSKYWHSLQRFASTVGYSLVEAQKCENEEAETVTAMASLSVGVKPAEKRPEDE
PMEEEPPL

>Oryzias latipes_HDAC4(ENSORLP_22663)
LKAKRLYRLSCLVDVSPAALPSQVPPTSTAILPMDLRVVDHHHKKKQTPPGHQEHQLQHE
LVALKHKQQLQRQLLIAEFQRQHEQLSRQHEAQLQEHIKHQQDLLALKHQQELLEHHRKM
EQQRHDQLEKQQREQKLQQLKNKERGQESAVASTEVKMRLQEFVLNKKKALAQRNLNHCL
PSDLRYWYGKTHHSSLDQSSPPQTALSAYNHPMLGTYDLKDDFPLRKTASEPNLKLRSRL
KQKVAERRSSPLLRRKDGLITTAKKRSLDVAEPACNSAPGSGPSSPNNSSSNIPNENGIP
ISSSHGEASLLQRLAAREGSVSQLSLYTSPSLPNITLGLPATGPASAVVSGHQDGESHLA
LPALQQGIPLTPPFLPTAHLPSYLAPSALDREGPGGGTAGHNPLLQHVVLLEQGHSPMEK
HVQGALCHTVGLAGLPLPSPTVSKLVRGHRPLGRTQSAPLPQQPCGQAQALQQLVVQQQH
QQFLEKHKQLFQQQQQHLISKIMSKPGDPASAVGSSASLPGRQHQSHPEETEEELREHQG
LSSSSSSPSSAPMQETRLLRAIKQEPPDPEEQEEREQRERHSEPDFLFKQQQTLLLEQQR
IHQLRNYRATIEDSSLPGTLAGKRPLFRTQSSPASASLPMAVQESPVKHRFTTGLVYDSL
MQKHQCICGNSTIHPEHAGRIQSIWSRLQETGLRAHCEVIRGRKASPEELQTVHSEAHVQ
LYGTNPLRQRLDCKTCISSVNPVFVRLPCGGIGVDSDTIWNEVHSSSAARLAVGSVVELV
FKVASGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAIAAKLLQQRLNVSKILIVDWDVH
HGNGTQQAFYADPNVLYLSLHRYDDGNFFPGSGAPDEVGSGAGVGFNVNVAFTGGLEPPM
ADAEYLAAFRTVVMPIAKEFAPDMVLVSSGFDAVDGHAPPLGGYKVTSKCFGYLTRQLMD
LAGGRLVLALEGGHDLTAICDASEACISALLGNELEPIPEEVLQQRPNANAVSSLEKVME
THSKYWRSLQRSASTLCCSLSEALQHDVEEAETVSAMASLSVANKHIGKRAEEEPMEEEA
AM

>Takifugu rubripes_HDAC4(ENSTRUP_12899)
LSHFPVDVSAAALPMQVPPAATAILPMDLRVDHHHNHQQQPTFDHQEQQLQQELVALKHK
QQLQRQLLIAEFQRQHEQLSRQHEIQLQEHIKHQQDLLALKHQQELLEHQRKIEQQRHEQ
ELEKQQREYKLHQLKNKDRGQESAIASTEVKMRLQEFVLNKKKALAQRNLNHCLPSDPRY
WYGKTQHSSLDQSSPPQTALSAYTHPMLGTYDSKDDFPLRKTASEPNLKLRSRLKQKVTE
RRSSPLLRRKDGPIPSAKKRSLDVADSACNSAPGSGPSSPNNSSSNIPSENGITISSSPG
EASLLQRLAAREGSVSHLSLYTSPSLPNITLGLPATGPAASVVSGHKDGDSRLTLPALQQ
GIPLTSPFLPPTHLPSYLTSSALDREAPGGGAAGAHNPLLQHMVLLEQGHSPMVLTCLLF
GPFHNKSLGGLPLQSPSVSKLARGHRPLGRTQSAPLPQQQCGQAQALQQLVVQQQHQQFL
EKHKQQFQQQQHIISKIMSKPTDQVSAVSSSPSGPARQHQSHPEETEEELREHQGLPSSS
SPPTPSSLPVKEAGPMRSVVIKQEPVDPQEVEEKEQRERQAEKDFLFRQQQALLLEQQRI
HQLRNYQASMEAAGLPVSFAGHRPLSRAQSSPASASFPIVVPESTTKPRFTTGLVYDSLM
QKHQCMCGNTTIHPEHAGRIQSIWSRLQETGLRAHCECIRGRKASLEELQTIHSEAHVLL
YGTNPLRQKLDCKISLSSVSPMFVRLPCGGIGVDSDTIWNEVHSSTAARLAVGSVAELVF
KVASGELKNGFAVVRPPGHHAEESAPMGFCYFNSVAIAAKLLQQRLSVRKILIVDWDVHH
GNGTQQAFYADPGILYISLHRYDDGNFFPGSGAPDEVGSGAGVGFNVNMAFTGGLEPPMG
DVEYLAAFRTVVMPIANEFAPDVVLVSSGFDAVDGHASPLGGYKLTAKCFGYLTRQLMGL
AGGRVVLALEGGHDLTAICDASEACVSALLGNELEPIPDKLMQQRPNANAVRSMEKVLEA
HGKYWCSLQRSASTLGCSLSEALQRDTEEAETVSAMASLSVANKHMGKRSEEEPMEEETS

>Tetraodon nigroviridis_HDAC4(ENSTNIP_138)
ECALSSTEGILGKEQPLEVLKTSVLNHIPTVDINSALPLRLPPAAIPMDLRVDPQQQQQA
GGGGGPSVCDQQLQQELLTLKQKQQIQRQILIAEFQRQHEQLSRQHEAQLQEHIKQQQEL
LALKHQQELLEHQRKMENHRMEQELEKQQREQKLQLLKNKERGQESAVASTEVKMRLQEF
VLNKKKALAQRSLNQGGPHNDAPYCKTQHSSLDQSSPPQTGVSTYNQPVLGVYNPRDDFP
LRKTASEPNLKLRSRLKQKVSERRSSPLLRRRDSPITTAKKRSLDMADSACSSAPGSGPS
SPNNSSNNIPSENGVAVSVSNNTEVSLAQRMCTGAERGSANQLSLYTSPSLPNITLGLPA
TATATAASNVTSAQTDGGLQPALSLSPPFLSGSHLTPYLAEAGAGTGGHPAHSPLLQHMV
LMEQSPAQSPLVTGRSFSNMQNDSSISGSSFGAASMAKLQRQHRPLGRTQSAPLPQGSAA
QAHAQALALQQLVAMATERKPQPFMVRQTLHIFQMMTKPSESPMGRQHQSHPEETEEELR
EHQDGGALPAGVTIKQEPPDPQELQEEALHRERERQAEQQELLFRQQALLLEQQRIHQLR
NYQASMEAAGLSISFPGHRPLSRAQSSPASASSFPISVPASEPPTKPRFTTGLVYDSLMQ
KHQCMCGNTNNHPEHAGRIQSIWSRLQETGLRAQCECIRGRKATLEELQTVHSEAHVLLY
GTNPLRQKLDCSITPMFVRLPCGGIGVDSDTIWNEVHSSSAARLAVGSVAELVFKVATRE
LKNGFAVVRPPGHHAEESTPMGFCYFNSVAIAAKLLQQRLNINKILIVDWDVHHGNGTQQ
AFYDDPSVLYLSIHRYDDGNFFPGSGAPDEVGSGPGVGFNVNVAFTGGLEPPMGDAEYLA
AFRSVVMPIANEFAPDIVLVSSGFDAVEGHPPPLGGYTLTAKCFGYLTRQLMTLAGGRLV
LALEGGHDLTAICDASEACLAALLGQELDPLPKSVLEQRPNANAVRSLEKVLEIHSKYWR
SVQRYSLHLGLSLLEAKRGDSEEAEAVSAMASLSVANTNAIDQSRSEEEPMEEEEPL

>Gasterosteus aculeatus_HDAC4(ENSGACP_2894)
SVDVSSAALPMQVPPTTTAILPMDLRVVTGGAEALTCRSRPTDQPELQQELVTLKHKQQL
QRQLLIAEFQRQHEQLSRQHEVQLQEHVKHQQDLLALKHQQELLEHQRKMEQQHLEQEME
KQQREHKLLQLKNKERGQESAVASTEVKMRLQEFVLNKKKALAQRSLNHRLPSDPRFWYG
KTQHSSLDQSSPPQTALSAYTHPMLGTYDSKDDFPLRKTASEPNLKLRSRLKQKVTERRS
SPLLRRKDGPITTAKKRSLDVAESACNSAPGSGPSSPNNSSSNIPCENGVNISCSPGEAS
LLQRLAAREGSVSQLSLYTSPSLPNITLGLPATGQASSVGSVHQDGESRLALPALQQGIP
LTRPFLPTAHLPSYLASSALDREGGGGGVAGHNPLLQHMVLMEQSHNSMGLFFGLAGLPL
PSPSVSKLARGHRPLGRTQSAPLPQQQCGQAQALQQLVVQQQHQQFLEKHKQQFQQQQHI
INKASSSASGPARQHQSHPEETEEELREHQGLSLSSLSASCSASAQDTGPLRGLVIKQEP
SDPQEQQQEEREKMERLVEQDFLFRQQQALLLEQQRIHQLRNYQASMEAAGLSVSFAGHR
PLSRAQSSPASASFPMVVQEPPTKPRFTTGLVYDSLMQKHQCMCGNTTSHPEHAGRIQSI
WSRLQETGLRSHCECIRGRKASLEELQTVHSEAHVLLYGTNPLRQKLDCSVSPMFVRLPC
GGIGVDNDTIWNEVHSSSAARLAVGSVVELVFKVASGELKNGFAVVRPPGHHAEESTPMG
FCYFNSVAIAAKLLQQRLNVSKVLIVDWDVHHGNGTQQAFYADPNVLYLSLHRYDDGNFF
PGSGAPDEVGSGAGVGFNVNMAFTGGLEPPMSDAEYLAAFRTVVMPIANEFAPDVVLVSS
GFDAVDGHAPPLGGYKLTAKCFGYLTRQLMGLAGGRLVLALEGGHDLTAICDASEACVSS
LLGNELDPIPEEVLQQIPNANAVRSMEKVLEIHNKYWRSLQRSASTLGCSLSEALRRDAE
EAETVSAMASLSVANKLVGKRAEEEPMEEEATM

>Homo sapiens_HDAC5(ENSP_337290)
MNSPNESDGMSGREPSLEILPRTSLHSIPVTVEVKPVLPRAMPSSMGGGGGGSPSPVELR
GALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQ
QEMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIAS
TEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKL
PLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEI
TGAGPGASSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQ
FSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMST
SSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATS
MRTVGKLPRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGE
LPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEED
CIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQ
SSPAAPGGMKSPPDQPVKHLFTTGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAV
GCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVL
IVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWT
GGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGH
LTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNINAVA
TLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQAAAAR
EHSPRPAEEPMEQEPAL

>Mus musculus_HDAC5(ENSMUSP_102770)
MNSPNESADGMSGREPSLEILPRTPLHSIPVAVEVKPVLPGAMPSSMGGGGGGSPSPVEL
RGALAGPMDPALREQQLQQELLVLKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQ
QQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQ
EFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLPLLGPYDS
RDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGTGPGVS
SVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMIPQHRALPLDSSPNQFSLYTSPS
LPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLL
GVALEGDTSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLP
RHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQMQLGKILTKTGELSRQPTTH
PEETEEELTEQQEALLGEGALTIPREGSTESESTQEDLEEEEEEEEEEEEDCIQVKDEDG
ESGPDEGPDLEESSAGYKKLFADAQQLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGSM
KSPTDQPTVVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLGKC
ERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAMLPCGGIGVD
SDTVWNEMHSSSAVRMAVGCLVELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNS
VAITAKLLQQKLSVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAP
EEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAQEFSPDVVLVSAGFDAVE
GHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVEL
QPLDEAVLQQKPSVNAVATLEKVIEIQSKHWSCVQRFAAGLGCSLREAQTGEKEEAETVS
AMALLSVGAEQAQAVATQEHSPRPAEEPMEQEPAL

>Bos taurus_HDAC5(ENSBTAP_53450)
RHSGPGLLSRPSVCYRLSLLTSPQLHPLPSQPPTPASCRPRAGMNSPTESADGMPGREPA
LEILPRTPLHGIPVTVEVKPVLPGAMPSSMGGGGGGSPSPVELRGALAGPVDPTLREQQL
QQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKHLASPLPLQQQQEMLAAK
RQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSK
EPTPGGLNHSLPQHPKCWGTHHASLDQSSPPQSGPPGTPSSYKLPLLGPYDSRDDFPLRK
TASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGVSAVCNSAPG
SGPSSPNSSHSTIAENGFTGSVPNIPTEMLPQHRALPPDTSPNQFSLYTSPSLPNISLGL
QATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGALTGKFMSTSSIPGCLLGVALEGDS
SPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRT
QSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEEL
TEQQDALLGEGALTIPREGSTESESTQEDLEEEEEEEEEEEEEEEEDCIQVKDEERESGA
EEGPDLEESSAGYKKAFADTQQLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPP
DQPTKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGR
KATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAMLPCGGIGVDSDTVWN
EMHSSSAVRMAVGCLVELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITTK
LLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGG
PGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPL
GGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEA
VLQQKPNINAVATLEKVIEIQSKHWSCVQRFAAGLGRSLREAQAGETEEAETVSAMALLS
VGAEQAQAAAAREHSPRPAEEPMEQEPAL

>Canis familiaris_HDAC5(ENSCAFP_21172)
RHSSPGLLSRPSVCYRLSLLTSPQLHPLPSQPPTPASCGPRAGMNSPTESADGMSGREPS
LEILPRTPLHGIPVAVEVKPVLPGAMPSSIGGGGGGSPSPAELRGALAGPVDPALREQQL
QQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKVRKEAMPLQQQQEMLAAK
RQQELEQQRQQEQRRQEELEKQRLEQQLISLRNKEKSKESAIASTEVKLRLQEFLLSKSK
EPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLPLLGPYDSRDDFPLRK
TASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGVSSVCNSAPG
SGPSSPNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGL
QATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGALTGKFMSTSSIPGCLLGVALEGDT
SPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRT
QSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEEL
TEQQEALLGEGALTIPREGSTESESTQEDLEEEEEEEEEEEEEEEEECIQVKDEEGESGA
EEGPDLDESSAGYKKVFSDAQQLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPP
DQPAKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGR
KATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAMLPCGGIGVDSDTVWN
EMHSSSAVRMAVGCLVELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITTK
LLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGG
PGIGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPL
GGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEA
VLQQKPNINAVATLEKVIEIQSKHWSCVQRFAAGLGRSLREAQAGETEEAETVSAMALLS
VGAEQAQAAAAREHSPRPAEEPMEQEPAL

>Monodelphis domestica_HDAC5(ENSMODP_14720)
MLLVPKAQGLVKMLQTIYETESCFSSDGMSGREQSLEILSRTPLHSIPVAVEVKPVLCGA
MPGSVGGGRGGGSPGPAELRGVGPAAIDPVLREQQLQQELLALKQQQQLQKQLLFAEFQK
QHDHLTRQHEVQLQKHLKQQQEMLAAKRQQELEQQRKREQQRQEELEKQRLEQQLLILRN
KEKSKESAIASTEVKLKLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQS
GPPGTPPSYKLPLLGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTV
ISTFKKRAIEITGAGAVSSVCNSAPGSGPSSPNSSNSTIAENGFTGSVPNIPTEMLPQHR
TLTLDSSPNQFSLYTSPSLPNISLGLQATVTVTNSHLTAPQKLSTQQEAERQAIQSLRQG
GALTGKFMSTSSIPGCLLGVALEGDVNPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSP
LVTGERIAANMRTVGKLPRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQ
LGKILTKTGELPRQPTTHPEETEEELTEHQEGLIGEGPLPGPGEGSTESESPQEDLEEED
EEDEEDEDCIQVKDEGSEIGLDESPLLEESSGDYKQVFSDAQQLQSLQVYQAPLSLASVP
HQALGRTQSSPAAPLGMKSAPELPTKHLFTTGVVYDTFMLKHQCMCGNTHIHPEHAGRIQ
SIWSRLQETGLLSKCERIRGRKATLDEIQTVHSEHHALLYGTSPLNRQKLDSKKLLGPIS
QKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLVELAFKVASGELKNGFAIIRPPGH
HAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYSDPSVLYISL
HRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAQEF
CPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMKLAGGRVVLALEGGHDLTAIC
DASEACVSALLSVELEPLDETVLQQKPNINAVATLEKVIEIQSKHWSCVQRNSTSVGRSL
QEAQAGDVEEAETLSAMALLSVGAEQA

>Danio rerio_HDAC5(ENSDARP_100072)
MNSPNTPVDVKTLLPSGMQSPVGGGGDQGGGSGGPVDLRTDPRLSALSAVDPSLREKQLQ
HELLLLKQQQELQKQLLFAEFQKQHEVLTRQHEVQLQEHLKQQQEILAAKRQQELEQKRK
LEQQRHEEMEKQRLEQQLIMLRNKEKGKESAIASTEVKLKLQEFLLSKKEPGPGGLNHSF
PQKCWGAHHTSLEQSSPPQSNTPGTPPSYKLPPLLGSYEGKDDFPLRKTASEPNLKVRSR
LKQKVAERRSSPLLRRKDGTVISTFKKRAIEISVSSMCSSAPGSGPSSPNSSNCAIAENG
SSGSVPNIHAEQLRSLHQSLTGDGAPSPLSLYTSPSLPNISLGLPANAHITAPQKLSAQQ
EAERQTIQSLRQGGALTGKFISTSSLPTCLSTGAPHDPEPPAASNSHSSHSSLLQHVLLL
EQARQQSALLAVPMYGQSPLVTGERVSNNMRTVNKLPRHRPLSRTQSAPLPQTPQALQHL
VMQQQHQHFLEKQKHYQLNKILSKGTDLPRQPPTHPEETEEELTETAEMQDERGEGPDHV
REGLQKDSSGETTPPSERIVPLKGESTESDLEEEDDEDEAVELRECDEDAPYGQYLDQQH
VQQLNVFQASLSITGMPHRPLGRAQSSPVTSSLKGTTLNEVPIKHLFTTGLVYDTFMLKH
QCMCGNTNIHPEHAGRIQSVWSRLQETGLLGRCERIRGRKATLDEIQTVHSEYHTLLYGT
SPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSGAVRMAVGCVIELAFK
VAAGELKNGFAVVRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLGVGKILIIDWDIHHG
NGTQQAFYNDPNVLYISLHRYDDGNFFPGSGAPEEVGVGPGEGFNVNIAWTGGVEPPMGD
VEYLTAFRTVVMPIANEFSPDVVLVSAGFDAVEGHQSPLGGYNVTAKCFGHLTKQLMKLA
GGRVVLALEGGHDLTAICDASESCVEALLGDELNPLPLTVLQQKPCPKATASLERVIEIQ
SKHWTSLQRLAPTVGQSLLDAQRREKDEADTLTAMASLTVDNEQQTTSTETSRSAEEPME
EEPVL

>Oryzias latipes_HDAC5(ENSORLP_21264)
PVDLRNEPRVGSLSGGVAVDTTLREQQLQQELVLLKQQQELQKQLLFAEFQKKHEVLTRQ
HEVQLQEHLKQQQELLAAKRQQELEQKRKLEQQRHEEQEKQRLEQQLLLLRNKEKGRESA
IASTEVKLKLQEFLLSKKEPGPSGLNHSFSPKCWAAQHPSLDQGSPPQGSTPGTPPSYKL
PSLLGSYEGKDDFPLRKTVSEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAIE
ISVSSMCSSAPGSGPSSPNSSNTAISNGSTGSVPNIQTELRSLHQMLGADGTLSLYTSPS
LPNISLGLPANTHIPPTQKLSAQQEAERQAIQSLRGGGALTGKFLSTSSLPAETLIQLPF
SGGGHEVEAPPPTSHSTHSSLLQHVLLLEQARQQSAMLVPVYNQSPLVTAERGVASGLRS
VNKLPRHRPLARTQSAPLPQSPQALQQLVVQQQHQHFLEKHYKVRTQTHTMLSKGADLPR
PPPTHPEETEEELTESSDMQEDEGEASVSREGSHDRKHASEQLFVHVKGEEEHSSGQVRD
ESTESELEEEEEDDERLKGSHTRKRSADATPLQPLGVFQSSLAHKYLGRSKSSPTASINP
VKHLFTTGLVYDSLMLKHQCVCGNAHIHPEHAGRVQSIWSRLQETGLLGRCERIRGRKAS
LDEIQSVHSEFHTLLYGTSPLNRHKLDHKKLLGPISQKMYAVLPWEASGSPQPCPSLFGL
SRATLWAFGSVPGLILSRMLSSDRGFCFFNSVAIAAKLLQQKLGVGKILIVDWDIHHGNG
TQQAFYTDPSVLYISLHRYDDGNFFPGSGAPEEVGSGAGVGFNVNIAWTGGVEPPMGDVE
YLVAFRSVVMPIAQRFSPDVVLVSAGFDAVEGHQSPLGGYNVSAKCFGQLTQLLMGLAGG
RVVMALEGGHDLTAICDASEACVSALLGDLWPLDNPCPKACASLERVIEIQSKHWSCLQP
LSQTSGRSQPDGGQGTQSEKDEAETVSAMASLSVDVEQPVSVPESTDSSRSTEEPMEEEP
IL

>Takifugu rubripes_HDAC5(ENSTRUP_30067)
IDGGPGESAGGGGGGPVDLRTDPRVGSLSGGVAVVDTAMREQQLQQELVLLKQQQELQKQ
MLFAEFQKKHEVLTRQHEVQLQEHLKQQQELLAAKRQQELEQKRKLEQQRHEEQEKHRLE
QQLLLLRNKEKGKESAIASTEVKLKLQEFLLNKKEPSFSGLNHSFSTKSWGAQHTSLEQC
SPPQSNTPGTPPSYKLPPLLGNYEGKDDFPLRKTVSEPNLKVRSRLKQKVAERRSSPLLR
RKDGTVISTFKKRAIEISVSVSRPVSSLCSSAPGSGPSSPNSSNSAIANGNTGSVPNIQT
ELRSLHQTLGADGTLSPLNLYTSPSLPNISLGLPANTHITATQKLSTQQEAERQAIQSLR
GGGALTGKFLSTSSLPAGVGHDVENPAPSSHSAHSSLLQHVLLLEQARQQTAMLADSVPM
YSQSPLVTAERGVSSGMRTVNKLPRHRPLARTQSAPLPQSPQALQQLVVQQQHQHFLEKH
YKNNNISLCVKMLSKGTELPRPPPTHPEETEEELTETNDITHSSERLGVPAKGDEEYVHI
KGESTESELDEEEEDEDSVQLREVDEDDHEGYKVHGPIQESAASVALESTATLLYIETTE
ALQLGMFQSSLPHRPLGRAQSSPAGSVNPIKHFFTTGRLVYDSLMLKHQCICGNAHIHPE
HAGRVQSIWSRLQETGLLGRCERIRGRKASLDEIQSVHSEFHTLLYGTSPLNRHKLDHKK
LLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGSVIELAFRVAAGELKNGFAV
VRPPGHHAEESTAMGFCFFNSVAITAKLLQQKMGVGKILIVDWDIHHGNGTQQAFYSDPN
VLYISLHRYDDGNFFPGSGAPEEVGSGGGNGFNVNIAWTGGVEPPMGDVEYLNAFRYVVM
PIAQHFSPDVVLVSAGFDAVEGHQSPLGGYNVSAKCFGQLTQLLMGLAGGRIVMALEGGH
DLTAICDASESCVSALLGDLSDSAFQWPQEKPCPKAWASLERVIEIQGKHWPCLQSLSHT
STHSLSDAPKAAQGQSEDEAETVSAMASLSVDVEQQQQTSDHMWVHRSTEEPMEEEPVL

>Tetraodon nigroviridis_HDAC5(ENSTNIP_17010)
NSQGGGGGPVDLRTEPRVGSLSGGVAVVDTTMREQQLQQELVLLKQQQELQKQMLFAEFQ
KKHEVLTRQHEVQLQEHLKQQQELLAAKRQQELEQKRKLEQQRHEEQEKHRLEQQLLLLR
NKEKGKESAIASTEVKLKLQEFLLNKKEPSFSGLNHSFSTKSWGAQHTSLEQCSPPQTNT
PGTPPSYKLPPLLGSYEGKDDFPLRKTVSEPNLKVRSRLKQKVAERRSSPLRRKDGTVIS
TFKKRAIEISAAAPPVSSLCSSAPGSGPSSPNSSNSAIANGNTGSVPNIQTELRSLHQTL
GADGTLSPLNLYTSPSLPNISLGLPANTHITVGQPTATQKLSTQQEAERQAIQSLRGGGA
LTGKFLSTSSLPAGGGHDVDTPASSSHSAHSSLLQHVLLLEQARQQTAMLADPVPMYNQS
PLVTAERGVSSGMRAVNKLPRHRPLSRTQSAPLPQSPQALQQLVVQQQHQHFLEKHSLQR
SNKPLCVKMLSKGTELPRPPPTHPEETEEELTETNDMQEDDVGLGVPLKGEEEYVHIKGE
STESELDEEEEDEDSVQLREGDEEEREGYKRAFPAEQALQQLGMFQSPHRPLGRAQSSPA
GSVNPIKHFFTTGLVYDSLMLKHQCICGNAHIHPEHAGRVQSIWSRLQETGLLGRCERIR
GREASLDEIQSVHSEFHTLLYGTSPLNRHKLDHKKLLGSPISQKMYAVLPCGGIGVDSDT
VWNEMHSSSAVRMAVGSVIELAFRVAAGELKNGFAVVRPPGHHAEESTAMGFCFFNSVAI
TAKLLQQKMGVGKILIVDWDIHHGNGTQQAFYSDPSVLYISLHRYDDGNFFPGSGAPEEV
GSGAGNGFNVNIAWTGGVEPPMGDVEYLTAFRYVVMPIAQHFSPDVVLVSAGFDAVEGHQ
SPLGGYNVSAKCFGRLTQLLMDLAGGRVVMALEGGHDLTAICDASEACVSALLGDLSDSA
LQWPQEKPCPKAWASLERVIEIQSKHWPCLQSLSHISPSLSEVPKAAQGQSEDEAETVSA
MASLSVDVEQQQVSALNSMETSRSTEEPMEEEPVL

>Gasterosteus aculeatus_HDAC5(ENSGACP_6953)
TDSCSDGLRNPGFSSIARSLFVLPAVVEVKSSLPSGACPGEGPGGGGPVDLRTEARVGSL
PVGAAAAVDTAMREQQLQQELVLLKQQQELQKQLLFAEFQKKHEVLTRQHEVQLQEHLKR
NKEKGKESRSRPHHRPRRRPAPQIPPHLTLLLCFSFFWKGAIASTEVKLKLQEFLLNKKE
PGIGGLNHSFSPKCWYRGAQHISLEQGSPPQSNTPGTPPSYKLPPLLGNYDGKDDFPLRK
TVSEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAIEISAVSPPVSSLCNSAPG
SGPSSPNSSNSAIANGNTGSVPNIQTELRSLHQTLGADGTLSPLNLYTSPSLPNISLGLP
ANTHITTAQALSNQQEAERLAIQSLRGGGALTGKFLSTSCLPAAGVGHEVEPPSSHSAHS
SLLQHVLLLEQARQQTTMLAAMTLRPHPVPMYSQSPLVTAERGASSGMRAVNKLPRHRPL
ARTQSAPLPQSPQALQQLVVQQQHQHFLEKHYKVKKKKKEILSKGVDLPRPPPTHPEETE
EELTETNDMQEDDEGPSLHRFGIFDSISTNGESTESELDEEEEEDDIIQLRECDEESPPT
HGESPSSQQGAQQHSLYIEATALQQLGVFQSLLPHRPLGRAQSSPAAPVNPIKHLFTTGL
VYDSLMLKHQCVCGNAHIHPEHAGRVQSIWSRLQETGLLGRCERIRGRKASLDEIQSVHS
EFHTLLYGTSPLNRHKLDHKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSAAVRMAV
GSVIELAFRVAAGELKNGFAVVRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLGVGKIL
IVDWDIHHGNGTQQAFYSDASVLYISLHRYDDGNFFPGSGAPEEVGSGAGVGFNVNVAWT
GGVEPPMGDVEYLTAFRSVVMPIAQQFSPDVVLVSAGFDAVEGHQSPLGGYNVSAKCFGQ
LTQLLMGLAGGRVIMALEGGHDLTAICDASEACVAALLGEPCDSGFQWPQEKPCPKAWAS
LERVIEIQDKHWSCLQSLSQTSGHSLSDDPVGARGQSEKDEAETVSAMASLSVDVERPGS
DPDNAETSRCTEEPMEEEPVL

>Homo sapiens_HDAC9(ENSP_408617)
MHSMISSVDVKSEVPVGLEPISPLDLRTDLRMMMPVVDPVVREKQLQQELLLIQQQQQIQ
KQLLIAEFQKQHENLTRQHQAQLQEHIKLQQELLAIKQQQELLEKEQKLEQQRQEQEVER
HRREQQLPPLRGKDRGRERAVASTEVKQKLQEFLLSKSATKDTPTNGKNHSVSRHPKLWY
TAAHHTSLDQSSPPLSGTSPSYKYTLPGAQDAKDDFPLRKTASEPNLKVRSRLKQKVAER
RSSPLLRRKDGNVVTSFKKRMFEVTESSVSSSSPGSGPSSPNNGPTGSVTENETSVLPPT
PHAEQMVSQQRILIHEDSMNLLSLYTSPSLPNITLGLPAVPSQLNASNSLKEKQKCETQT
LRQGVPLPGQYGGSIPASSSHPHVTLEGKPPNSSHQALLQHLLLKEQMRQQKLLVAGGVP
LHPQSPLATKERISPGIRGTHKLPRHRPLNRTQSAPLPQSTLAQLVIQQQHQQFLEKQKQ
YQQQIHMNKLLSKSIEQLKQPGSHLEEAEEELQGDQAMQEDRAPSSGNSTRSDSSACVDD
TLGQVGAVKVKEEPVDSDEDAQIQEMESGEQAAFMQQPFLEPTHTRALSVRQAPLAAVGM
DGLEKHRLVSRTHSSPAASVLPHPAMDRPLQPGSATGIAYDPLMLKHQCVCGNSTTHPEH
AGRIQSIWSRLQETGLLNKCERIQGRKASLEEIQLVHSEHHSLLYGTNPLDGQKLDPRIL
LGDDSQKFFSSLPCGGLGVDSDTIWNELHSSGAARMAVGCVIELASKVASGELKNGFAVV
RPPGHHAEESTAMGFCFFNSVAITAKYLRDQLNISKILIVDLDVHHGNGTQQAFYADPSI
LYISLHRYDEGNFFPGSGAPNEVGTGLGEGYNINIAWTGGLDPPMGDVEYLEAFRTIVKP
VAKEFDPDMVLVSAGFDALEGHTPPLGGYKVTAKCFGHLTKQLMTLADGRVVLALEGGHD
LTAICDASEACVNALLGNELEPLAEDILHQSPNMNAVISLQKIIEIQSKYWKSVRMVAVP
RGCALAGAQLQEETETVSALASLTVDVEQPFAQEDSRTAGEPMEEEPAL

>Bos taurus_HDAC9(ENSBTAP_4971)
TSFLVSPVDVKSEVPVGLEPISPLDLRTDLRMMMPVVDPVVREKQLQQELLLIQQQQQIQ
KQLLIAEFQKQHENLTRQHQAQLQEHIKLQQELLAIKQQQELLEKEQKLEQQRQEQEVER
HRREQQLPPLRGKDRGRERAVASTEVKQKLQEFLLSKSATKDTPTNGKNHSVSRHPKLWY
TAAHHTSLDQSSPPLSGTPPSYKYTLPGAQDAKDDFPLRKTASEPNLKVRSRLKQKVAER
RSSPLLRRKDGNVVTSFKKRMFEVTESSVSSSSPGSGPSSPNNGPTGNITENETSVLPPT
PHAEKMVSQQRILIHEDSMNLLSLYTSPSLPNITLGLPAVSTQLNASNSLKEKQKCETQT
LRQGVPLPGQYGGSIPASSSHPHVTLEGKPNSSHQALLQHLLLKEQMRQQKLLVAGGVPL
HPQSPLATKERISPGIRGTHKLPRHRPLNRTQSAPLPQSTLAQLVIQQQHQQFLEKQKQY
QQQIHMNKLLSKSIEQLKQPGSHLEEAEEELQGDQAMQEDRAPSSGHSTRRDSGACADDT
LGQAGAVKVKEEPVDSDEDAQIQEMESGEQAAFMQQQSFLEPQHTRAVSVRQAQLAPVGM
EGLEKERLVSKTHSSPAASTLPHPAMDRPLRPGSATGIAYDPLMLKHQCICGNSTTHPEH
AGRIQSIWSRLQETGLLNKCERIQGRKASLEEIQLVHSEHHSLLYGTNPLDGQKLDPRTL
LGDSSQKFFSSLPCGGLGVDSDTIWNELHSSGAARMAVGCVIELASRVASGELKNGFAVV
RPPGHHAEESTAMGFCFFNSVAITAKYLRDQLNISKILIVDLDVHHGNGTQQAFYADPNI
LYISLHRYDEGNFFPGSGAPNEVGTGLGEGYNINIAWTGGLDPPMGDIEYLEAF

>Monodelphis domestica_HDAC9(ENSMODP_1749)
SFCPPVEVKSEVPVALDPVSPLDLRTDLRMMMPMVDPVLREKQLQQELLLIQQQQHLQKQ
LLIAEFQKQHENLTRQHQAQLQEHIKLQQELLAIKQQQELLEKEQKLEQQRQEQEVERHR
REQQLPPLRSKERGRERGVASTEVKQKLQEFLLSKSATKESPSNGKSHSASRHPKLWYTA
AHHTSLDQSSPPLSGTSPSYKYPLPGAQDAKDDFPLRKTASEPNLKVRSRLKQKVTERRS
SPLLRRKDGNVVTSFKKRVFEVTESSVSSSSPGSGPSSPSNGPATNMAESSETLLVPPAP
HPEQMVSQQRLLIHEESMNLLSLYPSPSLPNITLGLPAVPSQLSASSSIKDKQKCEAPAL
RPPGVTLPGQYTGSIPATSSHPHAALEGKPNSSHQALLQHLLLKEQMRQQKLLVTGGVPL
HPQSPLATKERVSPGLRGAHKLPRHRPLNRTQSAPLPQSTLAQLVIQQQHQQFLEKQKQY
QQQVHMNKMLSKSIEQLKQPGSQLEESEEELHGDQPMQEDRAPSSTNSVRSDSSLGPDDG
QRGPPLGPVKIKEEPLDSDDDTQPQEMESGEQAALVQQPFLEPQPGHTLPTYQAQLAPIG
TEGFDKHVLVSRARSSPAAPTLPHPATDRTLQRVSETGLVYDALMLKHQCICGRSALHPE
HAGRIQSIWSRLQETGLLSKCERIQGRKASLEELRLVHSDHHSLLYGTDPLSRQKLDPRM
LRGDTSQKVFSLLPCGGLGVDSDTIWNELHSSAAARMAVGCVIELASKVVSGELKNGFAV
VRPPGHHAEESTAMGFCFFNSVAITAKYLQEQFNVAKILVVDLDVHHGNGTQQAFYADPS
ILYISLHRYDEGNFFPGSGAPNEVGSGPGEGYNVNIAWTGGLDPPMGDAEYLAAFRTVVM
PIAREFDPDIVLVSAGFDAVEGHTPPLGGYKVTAKCFGNLTSQLMQVANGHVVMALEGGH
DLTAICDASEACVNALLENELDPVPEDILHQTPNRNAIASLQKTTEIQSKYWKSVERYSG
GALTGTEEQEQEETETVSALASLSVDVDQCFPKEDNRPAGEPMDEDPAL

>Ornithorhynchus anatinus_HDAC9(ENSOANP_15268)
FYDVTVDVKSEVPVGLEPITPLDLRTDLRMMMPMVDPVIREKQLQQELLLIQQQQQIQKQ
LLIAEFQKQHENLTRQHQAQLQEHIKKLQQELLAIKQQQELLEKEQKLEQQRQEQEVERH
HREQQLPPLRGKERGRERAVASTEVKQKLQEFLLSKSATKDSPTKGKNHSMSRHPKLWYT
TAHHTSLDQSSPPLSGTSPSYKYTLPGAQDANDDFPLRKTASEPNLKVRSRLKQKVAERR
SSPLLRRKDGNVITSFKKRVFEVTESSVSSSSPASGPSSPSNGPTGNVTENEASVLPSTP
HAEPMISQQRILIHEESMNLLSLYTSPSLPNITLGLPAVPSQLNASSTLKEKQKSESQTL
RQGVTLPGQYGGGTSASTGHSHAALEGKPNSSHQALLQHLLLKEQMRQQKLLVSGGVPLH
PQSPLATKERVSPGIRTAHKLPRHRPLNRTQSAPLPQSTLAQLVIQQQHQQFLEKQKQYQ
QQIHMNKILSKSIEQLKQPGSHLEEAEEELHGDHPMLEDRAPSSDHSIRNEGIGADADER
LGYPAGTVKVKEEPLDSADDAQAQQTESGEQAAFMPQVIGKDLAPGFVIKVII

>Gallus gallus_HDAC9(ENSGALP_17619)
MISSVDVKSEVPVGLEPISPLDLRTDLRMMVPMVDPIMREKQLQQELLLIQQQQQIQKQL
LIAEFQKQHENLTRQHQAQLQEHIKLQQELLAIKQQQELLEKEQKLEQQRQEQELERHRR
EQQLPPLRGKERGRERAVASTEVKQKLQEFLLSKSATKDSPANGKNHSVSRHPKLWYTAA
HHTSLDQSSPPLSGASPPYKYTLPGSQDAKDDFPLRKTASEPNLKVRSRLKQKVTERRSS
PLLRRKDGNVVSSFKKRLFEVTESSVSSSSPGSGPSSPSNGPTSSITESETSVLPSSIQA
EHLVSQQRLLIQDESVNLLSLYTSPSLPNITLGLPAVQSQISASSSFKEKQKGETQTLRP
GVALAGQYGGNLPPSSTHPHVALEGKPNSSHQALLQHLLLKEQMRQQKLLVTGAVPLHPQ
SPLAAKERGSPGVRAAHKLPRHRPLNRTQSAPLPQSTLAQLVIQQQHQQFLEKQKQYQQQ
IHMNKMLSKSIEQLKQPGSHLEEAEEELNGDHSMQEERAPASSASIRAESSSAGEDDRIG
QQVGAVKVKEEPPDSDEDTQTQQMESGEQAAFVQQEFLAHQRVHQLQIYQAQMATVGMAG
LDKHRLVSRTSSSPTDSTLPHPAVDQPSQHVYTTGVVYDSLMLKHQCMCGNYANHPEHAG
RIQSIWSRLQETGLLNKCERIRGRKASLEEIQLVHSEHHSLLYGTSPLNRQKLDPRKLLG
NVSQKLFSLLPCGGLGVDSDTVWNELHSAGAARMAVGCVIELAARVASRELKNGFAVVRP
PGHHAEESTAMGFCFFNSIAITAKYLRDKLNIGKILIVDLDVHHGNGTQQAFYADPSILY
VSLHRYDEGNFFPGSGAPNEVGSGPGEGFNINIAWTGGLDPPMGDVEYLTAFRTVIMPAA
NEFDPEIVLVSAGFDAVEGHDPPLGGYKVTAKCFGHLTKQLLKLADGRVVLALEGGHDLT
AICDASEACINALLGNELEPLPEDIVHQIPNMNAIASLKKTTEIQSKYWKSVEPYSVPVD
CALAESQKREREETETVSAMASLSVDVEQCFPQEGSRAAGEPMEEEPAL

>Taeniopygia guttata_HDAC9(ENSTGUP_2713)
MVDPIMREKQLQQELLLIQQQQQIHKQLLIAEFQKQHENLTRQHQAQLQEHIKLQQELLA
IKQQQELLEKEQKLEQQRQEQELERHRREQQLPPLRGKERGRERAVASTEVKQKLQEFLL
SKSATKDSPANGKNHSMSRHPKLWAAHHTSLDQSSPPLSGASPPYKYTLPGAQDAKDDFP
LRKTASEPNLKVRSRLKQKVTERRSKMEDESRDFNIMCTFQSGIHVCLICFSESSVSSSS
PGSGPSSPSNGPTSSTTETETSILPSNIQAEHLVSQQRLLIQDESVNLLSLYTSPLPNIT
LGLPAIQPQISHFGTQAIQSRNQKKQKGETPSLRQGVALAGQYGGNIPPSSTHPHIALEG
KPNSSHQALLQHLLLKEQMRQQKLLVTAVPLHPQSPLAAKERVSPGIRAAHKLPRHRPLN
RTQSAPLPQSTLAQLVIQQQHQQFLEKQKQYQQQIHMNKMLSKSIEQLKQPGSHLEEAEE
ELHGDHSMQEERAPSSSASVRAESSSAEEPLDSDEDVQTQQMESGEQAAFMQQVIGKDLA
PGFFLAHRHVHQLQIYQAQMATVGMAGSDKHRPLSRTPSSPTDSTLPHPDMDQPSQHVYT
TGVVYDSLMLKHQCMCGNYTNHPEHAGRIQSIWSRLQETGLLNKCERIRGRKASLEEIQL
VHSEHHSLLYGTSPLNRQKLDPRKLLGLVSQKLFSLLPCGGLGVKRDIKWSEMAFSTSGR
ICVIIPYLKKKFKSSEAKTNGFAVVRPPGHHAEESTAMGFCFFNSIAITAKYLRDKLNIG
KILIVDLDVHHGNGTQQAFYADPSILYVSLHRYDEGNFFPGSGAPNEVGSGPGEGYNINI
AWTGGLDPPMGDVEYLTAFRLV

>Danio rerio_HDAC9(ENSDARP_73615)
MLQTIYEADSCFSADGIGKHRLPLSPHDTDMHNVNNSVDIKPEVPLALDPGSPLDLRTDI
RMQGSASEVTVWERQLQQELLLIQKQQQIQKQLLITEFQKQHENLVRQHQAQIQEHLKLQ
QELHVMKQQQEQLEKERKLELQSQERELERHRREQQVLVLRNRERTRESLTGAVASNEVK
QKLQEFLLSKSTKDITLNGIPQKITQSSKLWYTASHHTSLEQSSPPLGGASSSCKISLPS
PQDYRDDFPLRKTVSEPNLKVRSRLKQKVAERRSSPLLRRKEGNIMTPFKKRALELLEST
ASSSAPGSGPSSPNGACSALGAENGPSSLPVTTRTERWPSQSRLLGPESSVSMLNLYTSP
SLPNISLGFSAASSPISAALGLQEKHVDNGAVSAVIQGLPTQLLGPVPLSVMETKVSSSH
QALLQHLLQKEQLRHQKILSSGQSPVHPPSPLAMMENSPSSTRPKLPRHRPLNRTQSAPL
PQSTLAQLVIQQQHQSFLEKQKQYQQQVHINKMLSKSIEQLRQPNVHLQESEEEEGEDCQ
EHAMQEESSPSGGVIRKHSPQNTSRSPTIPLDSHPGVIRVKEEPGASDDETMANQSSYIH
QVKGRMVIQAMI

>Oryzias latipes_HDAC9(ENSORLP_9115)
VSNYFAATDIKPDVPLAVEPLSPLDLRTDLRMLGPGSDHGLWERQLQQELLLIQKQQQIQ
KQLLISEFQKQHEKLTRQHQAQLQEHLKVSFSLNSNTAGEKCQNDPLKQSKVICRTYQKL
LGFYNRSSRPLSLRGKERSRESPTGAVASTEVKQKLQEFLLSKSAKDPVVNGTNHSFVHH
PKLWYTSSHHTSLDQSSPPLGGTSPTCHYTLPSPIENKDDFPLRKTASEPNLKLRSRLKQ
KVAERRSSPMLKRRDGNIMTPYKKRALELMDSSATNSAPGSGPSSPIGASSALGTENGPS
SLPTTTKTERWPSQPRLFRPEGSMSMLSLYTSPSLPNISFGLSNASSSISAAIGLKDRST
EIKHGLPGHLLGPVPLHTALESKVSPSHQALLQHLLQKEQMRQQKIITSGQSSMSPHPQS
PLAMKDRPSSSRPKLPKHRPLNRTQSAPLPQNTLAQLVIQQQHQHFLEKQKQYQQQVHIN
KLLSKSIEQLRQPSAHLQESEEELEDQQQQQHKDDIERMQEDALPPGGVIRKHMLSSSSG
SSSEMPDAPCGVIKVKEEPVDSEDEALTNQRLQSEQSTYLHQVKGRLVIRAMI

>Tetraodon nigroviridis_HDAC9(ENSTNIP_21609)
QTTLWASVDVKPDVPLSVEPLSPLDLRTDLRMLGPGSDPGLWERQLQQELLLIQKQQQIQ
KQLLISEFQKQHEKLTRQHQAQLQEHLKLQQELQAMKKQQELAEKERRLEKEQERHRREQ
HVSSLILRGKERSRESAVASTEVKQKLQEFLLSKSAKDPVSNGVTNSMIHHQKLWYTSSH
HTSLDQSSPPLGGTSPSCQYTLPSPIESKDDFPLRKTASEPNLKVRSRLKQKVAERRSSP
MLKRRDGNIMTPYKKRALELMDSTPTNSAPGSGPSSPIGASSALGAENGPSSLPTTTKTE
RWPSQPRLFRPEGSVSMLSLYTSPSLPNISFGISTASSPISAAMALSDRSTDMKHGLPGQ
LLGSVPLQTGLESKVSPSHQALLQHLLQKEQMRQQKMFSSGSMSSHPLSPLAMKDRPSSR
AKISKHRPLNMTQSAPLPQNTLAQLVIQQHQHFLEKQKQYQQQIHINKLLSKSIEQLRQP
SAHLQESEEEQEEQEELQQHREQAQRMPEDRVPPGGVIRKHTLSSSGSSGELPDGHYGVI
KVKEEPADSEDEGLSNPRLEPEQSAYLHQVKGRLVIRAMI

>Gasterosteus aculeatus_HDAC9(ENSGACP_10693)
SATVDVKPDAPLAVESLSPLDLRTDPRMLGSGSDPGMWERQLQQELLLIQKQQQIQKQLL
ISEFQKQHEKLTRQHQAQLQEHLKLQHELQAMKQQQELAEKERRLERNRREQHVSSLILR
GKERSREDLTGAVASTEVKQKLQEFLLSKSAKDPASNGLNHSFIHQQKLWYTSSHHTSLD
QSSPPLGGTSPTCRYTLPSPIESKDDFPLRKTASEPNLKVRSRLKQKVAERRSSPMLKRR
DGHIMTPYKKRALELMDSTPTNSAPGSGPSSPIGASSALGAENGPSSLPTTTKTERWPSQ
TRLFRPEGSVSMLSLYTSPSLPNISLGLSTASSPISAAIGLGDRSTEIKHGLPGHLLGPV
PLQTGLESKVSPSHQALLQHLLQKEQMRQQKMLSAGQGTLSSHPQSPLAMKDRPSSSRPK
LPKHRPLNRTQSAPLPQNTLAQLVIQQQHQHFLEKQKQYQQQIHINKLLSKSIEQLRQPS
AHLQESEEEQEEHHRELPQSMQEDRLPPGGVIRKHTLSSSSGSSGELPDVHYGVIRVKEE
PADSEDEALAAQGMEAEQSTYLHQVKGRLVIRAMI

>Homo sapiens_HDAC7(ENSP_369984)
MSDLRKRELGALFTSRGTGGVEWDGTQVSPGAHYCSPTGAGCPRPCADTPGPQPQPMDLR
VGQRPPVEPPPEPTLLALQRPQRLHHHLFLAGLQQQRSVEPMRLSMDTPMPELQVGPQEQ
ELRQLLHKDKSKRSAVASSVVKQKLAEVILKKQQAALERTVHPNSPGIPYRTLEPLETEG
ATRSMLSSFLPPVPSLPSDPPEHFPLRKTVSEPNLKLRYKPKKSLERRKNPLLRKESAPP
SLRRRPAETLGDSSPSSSSTPASGCSSPNDSEHGPNPILGSEALLGQRLRLQETSVAPFA
LPTVSLLPAITLGLPAPARADSDRRTHPTLGPRGPILGSPHTPLFLPHGLEPEAGGTLPS
RLQPILLLDPSGSHAPLLTVPGLGPLPFHFAQSLMTTERLSGSGLHWPLSRTRSEPLPPS
ATAPPPPGPMQPRLEQLKTHVQVIKRSAKPSEKPRLRQIPSAEDLETDGGGPGQVVDDGL
EHRELGHGQPEARGPAPLQQHPQVLLWEQQRLAGRLPRGSTGDTVLLPLAQGGHRPLSRA
QSSPAAPASLSAPEPASQARVLSSSETPARTLPFTTGLIYDSVMLKHQCSCGDNSRHPEH
AGRIQSIWSRLQERGLRSQCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLKLDNGKL
AGLLAQRMFVMLPCGGVGVDTDTIWNELHSSNAARWAAGSVTDLAFKVASRELKNGFAVV
RPPGHHADHSTAMGFCFFNSVAIACRQLQQQSKASKILIVDWDVHHGNGTQQTFYQDPSV
LYISLHRHDDGNFFPGSGAVDEVGAGSGEGFNVNVAWAGGLDPPMGDPEYLAAFRIVVMP
IAREFSPDLVLVSAGFDAAEGHPAPLGGYHVSAKCFGYMTQQLMNLAGGAVVLALEGGHD
LTAICDASEACVAALLGNRVDPLSEEGWKQKPNLNAIRSLEAVIRVHMGALTLSQIPGHG
SSQQQAGGAFSWPGHPCRAAVVMVNTGAACSAWPPVQTPGCLECQGLTKKKWRQ

>Mus musculus_HDAC7(ENSMUSP_129577)
MDLRVGQRPTVEPPPEPALLTLQHPQRLHRHLFLAGLHQQQRSAEPMRLSMDPPMPELQG
GQQEQELRQLLNKDKSKRSAVASSVVKQKLAEVILKKQQAALERTVHPSSPSIPYRTLEP
LDTEGAARSVLSSFLPPVPSLPTEPPEHFPLRKTVSEPNLKLRYKPKKSLERRKNPLLRK
ESAPPSLRRRPAETLGDSSPSSSSTPASGCSSPNDSEHGPNPALGSEALLGQRLRLQETS
LAPFALPTVSLLPAITLGLPAPARADGDRRTHSTLGPRGPVLGNPHAPLFLHHGLEPEAG
GTLPSRLQPILLLDPSVSHAPLWTVPGLGPLPFHFAQPLLTTERLSGSGLHRPLNRTRSE
PLPPSATASPLLAPLQPRQDRLKPHVQLIKPAISPPQRPAKPSEKPRLRQIPSAEDLETD
GGGVGPMANDGLEHRESGRGPPEGRGSISLQQHQQVPPWEQQHLAGRLSQGSPGDSVLIP
LAQVGHRPLSRTQSSPAAPVSLLSPEPTCQTQVLNSSETPATGLVYDSVMLKHQCSCGDN
SKHPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLK
LDNGKLTGLLAQRTFVMLPCGGVGVDTDTIWNELHSSNAARWAAGSVTDLAFKVASRELK
NGFAVVRPPGHHADHSTAMGFCFFNSVAIACRQLQQHGKASKILIVDWDVHHGNGTQQTF
YQDPSVLYISLHRHDDGNFFPGSGAVDEVGTGSGEGFNVNVAWAGGLDPPMGDPEYLAAF
RIVVMPIAREFAPDLVLVSAGFDAAEGHPAPLGGYHVSAKCFGYMTQQLMNLAGGAVVLA
LEGGHDLTAICDASEACVAALLGNKVDPLSEESWKQKPNLSAIRSLEAVVRVHRKYWGCM
QRLASCPDSWLPRVPGADAEVEAVTALASLSVGILAEDRPSERLVEEEEPMNL

>Bos taurus_HDAC7(ENSBTAP_38136)
LGNRSPAGLSRSPCPLCAPSGWPRPRADTPGPQPQPMDLRVGQRPPVEPPPEPTLLALQH
PQRLHHHLFLAGLQPQRSAEPMRLSMDTPMPELQMGQQEQELRQLLNKDKSKRSAVASSV
VKQKLAEVILKKQQAALERTVHPNSPSVPYRTLEPLETEGAARSMLSSFLPPVPSLPCDP
PEHFPLRKTVSEPNLKLRYKPKKSLERRKNPLLRKESAPPSLRRRPAETLGDSSPSSSST
PASGCSSPNDSEHGPNPVLGSEALLGQRLRLQETSLAPFALLPTITLGLPAPARADGDRR
THATLGPRGPVLGNPHAHLFLPHGLEPEAGGPLPSRLQPILLLDPSVTHTPLLTVPGLGP
LPFHFAQSLLTTERPSGSGLHRPLSRTRSEPLPPSATTPSLLGPLQPRLERLKPHVQLIK
RSAKPSEKPRLRQIPSAEDLETDGGSVGPLRDDGLEHRESSHGQQEARGTVPLQQHQQVF
LWEQQRLAGRLPRGATGDSVLLPLAPGSHRPLSRAQSSPAAPASLSTPEPASQARILPSS
ETPARTLPFTTGLVYDSVMLKHQCSCGDNSRHPEHAGRIQSIWSRLLERGLRSQCESLRG
RKASLEELQSVHSERHVLLYGTNPLSRLKLDNGKLAGLLAQRMFVMLPCGGVGVDTDTIW
NELHSSNAARWAAGSVTDLAFKVASRELKNGFAVVRPPGHHADHSTAMGFCFFNSVAIAC
RQLQQQGKASKILIVDWDVHHGNGTQQTFYQDPNVLYISLHRHDDGNFFPGSGAVDEVGA
GSGEGFNVNVAWAGGLDPPMGDPEYLAAFRIVVMPIAREFSPDLVLVSAGFDAAEGHPPP
LGGYHVSAKCFGYMTQQLMSLAGGAVVLALEGGHDLTAICDASEACVAALLGNKVDPLSE
EGWKQKPNLNAIRSLEAVIRVHSEYWGCMQRLASRPDSWVHRVPGADAEEVEAVTALASL
SVGILAEERTSGQLVEEEEPMNL

>Canis familiaris_HDAC7(ENSCAFP_13479)
LSLLSTDGTQVSPGAHCPRSPGTGLPRPRADTPGPQPQPMDLRVGQRPPVEPPPEPALLA
LQHPQRLHHHLFFAGLQQRSAEPMRLPMDTPGPQLQVGRQDQELRQLLNKDKSKRSAVAS
SVVKQKLAEVILKKQQAALERTVHPSSPSIPYRTLEPLETEGAARSMLSSFLPPVPSLPN
DPPEHFPLRKTVSEPNLKLRYKPKKSLERRKNPLLRKESAPPSLRRRPAETLGDSSPSSS
STPASGCSSPNDSEHGPNPVLGSEALLGQRLRLQETSLAPFALPTVSLLPAITLGLPAPA
RADADRRTHPTLGPRGPVLGGPHAPLFLPHGLEPEAGGALPSRLQPILLLDPSVSHTPLL
TVPGLGPLPFHFAQSLLTTERLSGSGLHRPLSRTRSEPLPPSATAPPPLGPLQPRLDRLK
PHIQLIKRPAKPSEKPRLRQIPSAEDLETDGGGVVSVGDDGLEHRESSHGQHDTRGPAAL
QQHQQVFLWEQQRLAGRLPRGGTGDSVLLPLAQGSHRPLSRAQSSPAAPASLPTPEPASQ
ARVLPSSETPARTLPFTTGLVYDSVMLKHQCSCGDNSRHPEHAGRIQSIWSRLQERGLRS
QCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLKLDNGKLAGLLAQRMFVMLPCGGVG
VDTDTIWNELHSSNAARWAAGSVTDLAFKVASRELKNGFAVVRPPGHHADHSTAMGFCFF
NSVAIACRQLQQQGKASKILIMDWDVHHGNGTQQTFYQDPSVLYISLHRHDDGNFFPGSG
AVDEVGAGSGEGFNVNVAWAGGLDPPMGDPEYLAAFRMVVMPIAREFSPDLVLVSAGFDA
AEGHPAPLGGYHVSAKCFGYMTQQLMSLAGGAVVLALEGGHDLTAICDASEACVAALLGN
KVDPLSEEGWKQKPNLNAIRSLEAVIRVHSKYWGCMQRLASCPDSWVPRVPGADTEEVEA
VTALASLSVGILAEERPPEQLVEEEEPMNL

>Ornithorhynchus anatinus_HDAC7(ENSOANP_2915)
AKPSEKPRLQQIPSAEDLEADGGDGRFGARDPERRELVLGRLEPEGPSEPLRHLGLNPQQ
QQQVPRAPRAVNGGPAAFAHPSHGPGEEEKPDLFGDLWVGRPPASGESTLQLSWETRSLS
TSSGLVYDSVMLKHQCSCGDNSNHPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEEL
QSVHAERHVLLYGTNPLTRLKLDNGKLAGILSQRMFVMLPCGGVGVDTDTWNEMHSSNAA
RWAAGSVTDLAFKVAARELKNGFAVVRPPGHHADLSTAMGFCFFNSVAIAARQLQQKGKV
GKILIVDWDVHHGNGTQQAFYQDPRVLYISLHRHDNGNFFPGSGAVDEVGAGSGEGFTVN
VAWAGGLDPPMGDPEYLAAFRTVVMPIAREFSPDLVLVSAGFDAADGHPPPLGGYCVSAK
CEVLGYMTQQ

>Gallus gallus_HDAC7(ENSGALP_10190)
REAEPGQQEQELRQILNKDKSKRSAVASTVVKQKLAEVILKKQQAAALERTSNPNPPAMP
YRSLEPLDPEGPSPPVLSTFLSPVPSTSLDPPEHFPLRKTASEPNLKVRCKPRKCLDRRK
NPLTRKESAPPSLKRRPPETIDSSPSSSSTPVSGCSSPNDSLPAEHGALPAASSMAHEAP
LAQRLMMQESSLAQFALQSAVSLPAITLGLPATTSARPSSLQGDADRRPFSGLAHRVPVL
NGPVLTGTHSPMFIPAGLEQHEAGSPLSPRLQPVIILEPSVTHAPLVAVPGLGTVPFSFA
PSLISAERLSLPGHHKPLGRTRSEPLPQNPKAIQQQLVYQQHHTQFLERLKQQTHLGKPA
LSPSPLCAHLSPLCMQRMVKTSEKPRLRQIPSSEDMEAEGMEAGAESSEQARARVEPTRP
GSSGKEPERPQKMLQPQEELILQQAYLWDPYQRVQHQLLKRQPLADSPMVPAVLAGHRPL
SRAQSSPATATVSLPAQDTTSKALSLPVQEQTTKPHFTTGLVYDSVMLKHQCSCGDNSNH
PEHAGRIQSIWSRLQERGLRSQCECLRGRKATLEELQCVHTERHVFLYGTNPLNRLKLDN
GKLAGILSQRMFVMLPCGGVGVDSDTIWNELHSSNAARWAAGSVTELAFKVASRELKNGF
AVVRPPGHHADPSTAMGFCFFNSVAIAARQLQQKGKLSKILIVDWDVHHGNGTQQIFYRD
PDVLYISLHRHDDGNFFPGSGAADEVGAGPGEGFNVNIAWTGGLDPPMGDPEYLAAFRTV
VMPIAHEFSPDVVLVSAGFDAADGHPPPLGGYKVSAKCFGYMTKQLMSLAGGAIVLALEG
GHDLTAICDASEAYPSHLSPWQLDPLPEESMRQKPNANAVRSLEAVIQVQSKYWVAVQRF
ASKLSCSFLEAQHHEAEEVETVTALASLSVAVMVEKRPQDEPMEEEEPMNQ

>Taeniopygia guttata_HDAC7(ENSTGUP_3859)
TVPLSLAPSLEPAERLALPGQHKPLGRTRSEPLPPSPRAVQQHLLFQQHHAHFLRQQPLL
GKRPAKSSEKPRLRQIPSSEDMEAEGTLPEAEPGDPPRARPEPPRPGGSAKEPERTQKMI
PRKELVLLHALLWDSFQRVQQQLLKRQPLADPPVLPPGHRPLSRAQSSPTATVSLPAQDT
KALALPVQEQPPKPLFTTGTATPAELCFSRQVCPPGPLAANHPEHAGRIQSIWSRLQERG
LRSRCECLRGRKATLEELQSVHSERHVLLYGTNPLNRLKLDNGKLAGILSQRTFVMLPCG
GLGVDSDTIWNELHSSNAARWAAGSVTELAFKVATRELKNGFAVVRPPGHHADPSTAMGF
CFFNSVAIAARQLQQKGKLSKILIVDWDVHHGNGTQQIFYRDPEVLYISLHRHDDGNFFP
GSGAADEVGAGPGEGFNVNVAWAGGLDPPMGDPEYLAAFRTVVMPIAHEFCPDVVLVSAG
FDAAEGHPPPLGGYKVSAKCFGYMTKQLMSLAGGAVVLALEGGHDLTAICDASEACVSVL
LGHEPEPLPEDSLRQKPNANAVRSLEAVIQVQSKYWVAVQRFASKLGCSFLEAQHHEADE
VETVTALASLSVAVMVEKRAQEEPMEQEEPMTQ

>Takifugu rubripes_HDAC7(ENSTRUP_31266)
SQQQLHQHIRFNMEQRRREQEHHEKQQELQQLKHKDKSQQSAVASSLVKQKLQEVILKKQ
KQAALERTNSNSLSTPPVSYRKLGPEPSLPPQPLVSPTLQSSSEGSEGTPLRRAASEPNL
KVKHKLKKHLNTRKSPLTRKESAPPTVKHRVPDTLDSSPSSSSTPVSGCSSPNDSLPSEN
GLLPSAGVLSHEELSTDNRVMGSQDSLGPSIHTDVALACSHYPSIVTDQVTHSKNGSQTG
QGSPVFLPLSREDQAGQLSPHLPVIILEPSGLVHTPLLTEHHIVVELRNHLLFLYSLFSV
PGLDTVPLQFSPQLDHLAPGSAQPHKPLSRTRSEPLPQSQRALHTHLLQQQHSTQLLERL
KQQTHLGKVRASKCTHPYSQKANVPEKAALFVYAQLMSKSSEKPRLHQIPSEEMDSEDGG
ASSPTEPTYLSRVRAESLREAESVTSKGQEDQINLQHALILNQSLLWEQQKQLQQLHRQM
ETLAVPMLCTSGSAGSGISVHRPLSRTQSSPASTSLTLPEKALSLADTSIKPRFTTGLVY
DSQMLKHQCTCGDNSSHPEHAGRIQSIWSRLQERGLRGQCESIRGRKATLEELQSVHTER
HVLLYGTNPLNRLKLDNRKLAGILSQRMFVMLPCGGVGVDNDTIWNESHTSTASRMAAGS
VVELAFRVAKGELKNGFAVVRPPGHHADPSNPMGFCYFNSVAIAAKQLQHKLSVSKILIV
DWDVHHGNGTQEVFYSDPSVLYISLHRYDDGNFFPGSGSPAEVGSGAGEGFNVNISWTGG
LDPPMGDAEYLAAFRSVVMPIAQEFSPDVVLVSAGFDAAEGNPAPLGGYKVSAKCFSFLT
HQLMSLAGGRVVLVLEGGHDLTAICDASEACVSTLLGIQDPLAEEVLLKKPNANAVHSLQ
TVIKIQSQYWQSVKAHSGSVCLSYLAAQRRDCEETDAVNALASLSVGVLPNKSISDEPME
HDSDS

>Oryzias latipes_HDAC7(ENSORLP_1341)
RTSFSHQQLHQQIRFNMEQRRREQVRHETQQELQQLRHKDKSQQSAVASSLVKQKLQEVI
LKKQKQAALERTNPAHPVAYRYAHLKKLGPDPSAPAQPLVSPPSQSSPESSEGTPLRRAA
SEPNLKVKNKLKKHLNTRKSPLTRKESAPPTVKHRVPDTLDSSPSSSSTPVSGCSSPNDS
LPCENGLLPSAGGLSHEVGEAHKMLLRDGTLSSFTIQSPSTLPTITLGLPANSRADGEVS
PLKVSRVPMVTAGVSPVFLPISREDQGGQMGPHLPVIILESPGLVHPPLLTGRTVLVLTP
ADESLILMSNPSSSSSTVPSLDSVPLQFAHQLERLSPGGVQPHKPLSRTRSEPLPQTLHT
HLLQQQHNTQLLERLKQQTHLGQVLIVRLNVFLSKQLMSKSSEKPRLHQIPSEDMDSEDG
GGTSPSEPAYHNRVRAGSLREAETTSSKSHEEQLQHALILNQSLLWEQQKQLQQLHRQMK
TLAVPVLPGGCSGGGGIHRPLSRTQSSPASTSLTLPEKPLNLAAPEISSKPRFTTGLVYD
SQMLKHQCACGDNSSHPEHAGRIQSIWSRLQERGLRGQCESIRGRKATLEELQSVHTERH
VLLYGTNPLNRLKLDNRKLAGRTRIFSQRMFTMLPCGGVGVDNDTIWNESHTSTASRMAA
GSVVELAFRVAKGELKNGFAVVRPPGHHADPSNPMGFCYFNSVAIAAKQLQQKLSVSKIL
IVDWDVHHGNGTQEVFYNDRSVLYISLHRYDDGNFFPGSGSPAEVGSGAGEGFNVNLAWT
GGLDPPMGDAEYLAAFRSVVMPIAQEFSPDVVLVSAGFDAAEGNPAPLGGYKVSAKCFGF
LTHQLMSLAGGRLILALEGGHDLTAICDASEACVSALLGMQDSMPEDVLLQKPNANAVRS
LQTVIQIQSQFWQNVKAHSGTLGLSLLEAQSRDCEETDAVNALASLSVGVMPNKSLQDEP
MEHDSDPL

>Tetraodon nigroviridis_HDAC7(ENSTNIP_291)
PLRRAASEPNLKVKLKKHLNTRKSPLTRKESAPAYCQTKKLSVDFSSVISSSTPVSGCSS
PNDSLPSDNGLLPSAGGLSHEMSSAQKLLLRDGTLANFTIQSPSTLPTITMGLPANTKAE
GELSSLKVTRVPVVTGPGSPVFLPLSREDQAGQLSPHLPVIILEPSGLVHTPLLTVPGLD
TVQLQFSSHIDHLATGSAQPHKPLSRTRSEPLPQSQRALHTHLLQQQHSTQLLERLKQQT
HLGKVRASKCALSSHVHKKDIGAQLMSKSSEKPRLHQIPSEEMDSEDSGATSPTEPTHLS
RLRAESLREAESATSTGQEEQINLQHALILNQSLLWEQQKQLQQLHRQMETLAVPMLCTS
GGAGSGLGVHRPLSRTQSSPASTSLTLPEKSLSLAAPDTSIKPRFTTGLVYDSQMLKHQC
TCGDNSSHPEHAGRIQSIWSRLQERGLRGQCESIRGRKATLEELQSVHTERHVLLYGTNP
LNRLKLDNRKLAGILSQRMFVMLPCGGVGVDNDTIWNESHTSTASRMAAGSVVELAFRVA
KGELKNGFAVVRPPGHHADPSNPMGFCYFNSVAIAAKQLQHKLSVSKILIVDWDVHHGNG
TQEVFYSDPSVLYISLHRYDNGNFFPGSGSPAEVGTGAGEGFNVNIAWTGGLDPPMGDAE
YLAAFRSVVMPIAQEFSPDVLLVSAGFDAAEGNPALLGGYKVSAKCFSFLTRQLMSLAGG
RVVLVLEGGHDLTAICDASEACVSALLGMQDPLTEEVLLQKPNANAVRSLQTVIKIQSQY
WQSVKAHSGSACLSYLAAQRRDCEETDAVNALASLTVGVLSNESIPDEPMEHDSDS

>Homo sapiens_HDAC6(ENSP_398566)
MSGANRGRGQASSTMTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPN
LAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFP
EGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRV
LADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYC
MFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPH
LKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFD
ALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDP
CPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEP
PVLPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTL
TPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAA
CRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIV
DWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWN
GPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLL
MGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQV
HRRYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSAS
FGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGA
TPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQ
TTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGAS
ESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAG
LDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYC
QAYVHHQALLDVKNIAHQNKFGEDMPHPH

>Mus musculus_HDAC6(ENSMUSP_33501)
MTSTGQDSSTRQRKSRHNPQSPLQESSATLKRGGKKCAVPHSSPNLAEVKKKGKMKKLSQ
PAEEDLVVGLQGLDLNPETRVPVGTGLVFDEQLNDFHCLWDDSFPESPERLHAIREQLIL
EGLLGRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLAETYDSVYLHPNSY
SCACLATGSVLRLVDALMGAEIRNGMAVIRPPGHHAQHNLMDGYCMFNHLAVAARYAQKK
HRIQRVLIVDWDVHHGQGTQFIFDQDPSVLYFSIHRYEHGRFWPHLKASNWSTIGFGQGQ
GYTINVPWNQTGMRDADYIAAFLHILLPVASEFQPQLVLVAAGFDALHGDPKGEMAATPA
GFAHLTHLLMGLAGGKLILSLEGGYNLRALAKGVSASLHTLLGDPCPMLESCVVPCASAQ
TSIYCTLEALEPFWEVLERSVETQEEDEVEEAVLEEEEEEGGWEATALPMDTWPLLQNRT
GLVYDEKMMSHCNLWDNHHPETPQRILRIMCHLEEVGLAARCLILPARPALDSELLTCHS
AEYVEHLRTTEKMKTRDLHREGANFDSIYICPSTFACAKLATGAACRLVEAVLSGEVLNG
IAVVRPPGHHAEPNAACGFCFFNSVAVAARHAQIIAGRALRILIVDWDVHHGNGTQHIFE
DDPSVLYVSLHRYDRGTFFPMGDEGASSQVGRDAGIGFTVNVPWNGPRMGDADYLAAWHR
LVLPIAYEFNPELVLISAGFDAAQGDPLGGCQVTPEGYAHLTHLLMGLAGGRIILILEGG
YNLASISESMAACTHSLLGDPPPQLTLLRPPQSGALVSISEVIQVHRKYWRSLRLMKMED
KEECSSSRLVIKKLPPTASPVSAKEMTTPKGKVPEESVRKTIAALPGKESTLGQAKSKMA
KAVLAQGQSSEQAAKGTTLDLATSKETVGGATTDLWASAAAPENFPNQTTSVEALGETEP
TPPASHTNKQTTGASPLQGVTAQQSLQLGVLSTLELSREAEEAHDSEEGLLGEAAGGQDM
NSLMLTQGFGDFNTQDVFYAVTPLSWCPHLMAVCPIPAAGLDVSQPCKTCGTVQENWVCL
TCYQVYCSRYVNAHMVCHHEASEHPLVLSCVDLSTWCYVCQAYVHHEDLQDVKNAAHQNK
FGEDMPHSH

>Bos taurus_HDAC6(ENSBTAP_50519)
GQDLAKWKDRVRGEVSPAMTSTGQDSTTPKERRSRHNPHSPTHDSSITSKRGVKKSAILR
SSPSLAEVKKKGRMKKLSQTAEQDLIMGLQGLVRGSWDNQNPKVLHPGQCGMFLLIQALN
PFHCLWDDSFPERPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMET
TQYMNEEELHVLADTYDSVYLHPNSYTCACLASGSVLRLVDAVLEAEIRNGMAIIRPPGH
HAQHSLMDGYCMFNHVAVAARYAQQKHDIQRVLIVDWDVHHGQGIQFAFDQDPSVLYFSI
HRYEQGRFWPHLKASNWSTTGLGQGQGYTINVPWNQVGMQDADYIAAFLHVLLPVAFEFQ
PQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAEGKLILSLEGGYNLHSLAEGV
SATLHTLLGDPCPVLESPGAPCPSAQASLSCTLEALEPFWESLVRSVESLEEKDTVEKDD
VEEKEEERLPQSPELSVPIWPVLQARTGLVYDQQMMDHHNLWDNYHPEMPQRIHFIMHHL
DELGLGKRCHSLPARPATDAELLTCHSAEHLERLRATEKMKTRELRREGANYDSIYICSS
TFACAQLAAGAACRLVEAVLAGEVLNGVAVVRPPGHHAEPDAACGFCFFNSVAVAARHAQ
AISGHALRILIVDWDIHHGNGTQHIFEEDPSVLYISLHRYDHGTFFPMGNEGACTRIGKA
TGTGFTVNVAWNGPRMGDADYLAAWHRLVLPVAYEFNPELVLVSAGFDAARGDPLGGCQV
SPEGYAHLTHQLMGLANGHIILILEGGYNLTSISESMAACTRSLLGDPLPLLTRLRPPLS
GAQASITKTIQVHRRYWRSLRVMKRKNKEELSSSKLITKKPSQPASPGLANVTTTVEGNI
LETGMGQAASEASVKESTPDQTESATAPVELTQGQSSDTATQGAALDQTISEGATGGAEL
IQNPPASCINNRIPPALPVQGATAQTSPSKLMANLRILDLDSTTQEPSEEEGLLGEAAGG
QDTNESVPVQVFGDHADTDEVMFYAVRPLLWCPHLAAVCPIPETGLNVTQPCQDCGTLQE
NWVCLSCYQVYCGRYINAHMLQHHEGSGHPLVLSYADLSAWCYHCQAYVHHKDLLAVKNI
AHQNKFGEDIPHSD

>Canis familiaris_HDAC6(ENSCAFP_22990)
SVLYFSIHRYEQGRFWPHLKASNWSTIGFGQGQGYTINVPWNQVGMRDADYIAAFLRLLL
PVALEFQPQLVLVAAGFDALQGDPKGEMATTPAGFAQLTHLLMGLAGGKLILSLEGGYNL
RALAEGVSASLHTLLGDPCPILESPSAPCPSAQASLFCALEALEPFWEVLVRSAEALEED
ILEEEKAEKEEERPWQPSVLPVLTWPMLQARTGLVYDPAMMGHYNLWDNHHPEMPQRVFR
IMRRLEELGLAGRCLTLPTRPATDAELLTCHSAEYVGRLRATEKMKTRELHREGSNFDSI
YICPSTFACAQLATGSVCRLVEAVLAREVLNGTAVVRPPGHHAERDAACGFCFFNSVAVA
ARHAQAISGHALRILIVDWDVHHGNGTQHIFEEDPSVLYISLHRYDHGTFFPMGDEGASS
QVGQAAGTGFTVNVAWNGPRVGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPL
GGCQVSPEGYAHLTHLLMGLANGRVVLILEGGYNLTSISESMAACTRSLLGDPPPLLTLS
RPPLSGALASITETIQVHRRYWRSLRVMKVEDKEGPSTSELITKKVTQPANPGSAERMTT
PEGNILDIDTEKGPSASSVEESTPGQAKSETAVVEFNQDQSLEATTGETTLYQTIPEAAT
EGTTPGQTTSEEAVGGAEVIQTSCTDNQTPPTSPVQGATPQISPSKLIENLRTLELNIEA
EKAPESQIPEEEGLLGEAAGGQDVDDSVLNESCGDHADTDQVVLYAVTPLPWCPHLVAVC
PIPESGLDVTQPCQDCGVLQENWVCLSCYQVYCGRYISAHMLHHHEDSGHPLVLSYVDLS
TWCYNCEAYVHHQALLDVKNVAHQNKFGEDMPHSH

>Monodelphis domestica_HDAC6(ENSMODP_12731)
KRGVRKGSPIPRASPSLADVRRRGRAKKLSQVSELDLVTDLQDLDLEAGAAVPSGTGLVL
DERMSSFHCPWDESFPERPERLQAVQEQLARDCLLERCLLIEAQPATPEELQLVHSQEYV
DLMASTPQMTESERRALSDTYDSVYLHPNSFPCALLATGALLRLVDALMTGEIRNGLAVV
RPPGHHAQRESMNGYCMFNNIAIAARYAQERHHVARILIVDWDVHHGQGTQFIFEQDPSV
LCFSVHRYELGRFWPHLEASDWRATGHGKGQGYTVNVPWNQVGMRDGDYITAFLHVLLPI
ALEFQPQMVLVAAGFDAMLGDPKGEMAATPGGFAHLTHLLMGLAKGRLILSLEGGYNLHS
LALGVSATLQTLLGDPCPMLATPCAPCPSALASLSSTLAAHRPFWKVIQRFQSTSEDKED
EYRGVSLGPPPILESLGKSLEQALSLPPSRTGLVYDEKMMEHFNMWDSHHPERPERIAQI
AQHHMELGLTPRCFVLPARSATNQELLACHSEEYIERIRATSGLKPRDLHREGTSYNSIY
ISPHSFCCAQLAAGAACRLVEAILAREAPQVQNGLAIVRPPGHHAERDAACGFCFFNSVA
VAARHAQEVAGRALRILIVDWDIHHGNGTQHIFEEDPSVLYVSLHRYDHGAFFPMAEDGA
SSHVGRGQGEGFNVNVAWNGPRLGDPDYLTAMHHIVMPIAYEFNPELVLVSAGFDAARGD
PLGGCLVSPEGYAHMTHLLMGLAGGRIALVLEGGYNLTSISESMAACTRTLLGDPPPLMP
WLRPPLPGTFLSLAEVAHIHQKYWQSLRLNGEQSFGRGQGESTRMGGVIGLSPIHCPAVE
TEAEVEEKEIPPEPAKESTPGQKLPDQRPSKALAIGPELEKQPLSPGLDETLGLESLQLS
TCAPEELEAEPSIAKEKHPEDPGLLGEAAGGGGQAAATLLNVLGDQSEDEGATFYAVTPL
PWCPHLVTVRPVPEGGLDVTQPCQGCDTHVENWLCLSCYQVHCGRYVGAHMLQHHEASGH
PLVLSYADLSAWCYICQAYVNHEVLLEAKKTAYQAKFGEEMPTFPR

>Danio rerio_HDAC6(ENSDARP_95600)
HQGFFSSACLSVGSVLQLVDKVMTSQLRNGFSINRPPGHHAQADKMNGFCMFNNLAIAAR
YAQKRHRVQRVLIVDWDVHHGQGIQYIFEEDPSVLYFSVHRYEDGSFWPHLKESDSSSVG
SGAGQGYNINLPWNKVGMESGDYITAFQQLLLPVAYEFQPQLVLVAAGFDAVIGDPKGGM
QVSPECFSILTHMLKGVAQGRLVLALEGGYNLQSTAEGVCASMRSLLGDPCPHLPSSGAP
CESALKSISKTISDLYPFWKSLQTFEGGPLSEVSPLPAPVCAEVKVSSPITGLVYDQRMM
LHHNMWDSHHPELPQRISRIFSRHEELRLLSRCHRIPARLATEEELALCHSSKHISIIKS
SEHMKPRDLNRLGDEYNSIFISNESYTCALLAAGSCFNSAQAILTGQVRNAVAIVRPPGH
HAEKDTACGFCFFNTAALTARYAQSITRESLRVLIVDWDVHHGNGTQHIFEEDDSVLYIS
LHRYEDGAFFPNSEDANYDKVGLGKGRGYNVNIPWNGGKMGDPEYMAAFHHLVMPIAREF
APELVLVSAGFDAARGDPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISES
MSMCTSMLLGDSPPSLDHLTPLKTSATVSINNVLRAHAPFWSSLRVNIPESLRLSLPSPK
PKGKCTPGGKGKKSPRQSTPSQSPGQATHRPDQSGFDELTADLLSLNLNTSTSSNTSPES
VAVGGARRKVKPNTHRVSAGLESESPLKLNPEKAGAGDDTDVKAETPNRSISEPVVTCDS
SAVKDQESLVLEAAGGNTVQSVLERVFGAQATDVDTMYVVDPLPWCPHLESVRPVPAGGI
DVFQPCEECGGEAENWICLFCYKVLCGRYVNQHMVTHGQESGHPVVLSFADLSVWCYACE
SYVHNKVLHEAKNAAHLVKFGEGIHPFN

>Homo sapiens_HDAC10(ENSP_216271)
MGTALVYHEDMTATRLLWDDPECEIERPERLTAALDRLRQRGLEQRCLRLSAREASEEEL
GLVHSPEYVSLVRETQVLGKEELQALSGQFDAIYFHPSTFHCARLAAGAGLQLVDAVLTG
AVQNGLALVRPPGHHGQRAAANGFCVFNNVAIAAAHAKQKHGLHRILVVDWDVHHGQGIQ
YLFEDDPSVLYFSWHRYEHGRFWPFLRESDADAVGRGQGLGFTVNLPWNQVGMGNADYVA
AFLHLLLPLAFEFDPELVLVSAGFDSAIGDPEGQMQATPECFAHLTQLLQVLAGGRVCAV
LEGGYHLESLAESVCMTVQTLLGDPAPPLSGPMAPCQSALESIQSARAAQAPHWKSLQQQ
DVTAVPMSPSSHSPEGRPPPLLPGGPVCKAAASAPSSLLDQPCLCPAPSVRTAVALTTPD
ITLVLPPDVIQQEASALREETEAWARPHESLAREEALTALGKLLYLLDGMLDGQVNSGIA
ATPASAAAATLDVAVRRGLSHGAQRLLCVALGQLDRPPDLAHDGRSLWLNIRGKEAAALS
MFHVSTPLPVMTGGFLSCILGLVLPLAYGFQPDLVLVALGPGHGLQGPHAALLAAMLRGL
AGGRVLALLEENSTPQLAGILARVLNGEAPPSLGPSSVASPEDVQALMYLRGQLEPQWKM
LQCHPHLVA


>Mus musculus_HDAC10(ENSMUSP_80832)
MGTALVYHEDMTATRLLWDDPECEIECPERLTAALDGLRQRGLEERCLCLSACEASEEEL
GLVHSPEYIALVQKTQTLDKEELHALSKQYNAVYFHPDTFHCARLAAGAALQLVDAVLTG
AVHNGLALVRPPGHHSQRAAANGFCVFNNVALAAKHAKQKYGLQRILIVDWDVHHGQGIQ
YIFNDDPSVLYFSWHRYEHGSFWPFLPESDADAVGQGQGQGFTVNLPWNQVGMGNADYLA
AFLHVLLPLAFEFDPELVLVSAGFDSAIGDPEGQMQATPECFAHLTQLLQVLAGGRICAV
LEGGYHLESLAQSVCMMVQTLLGDPTPPLLGLMVPCQSALESIQSVQTAQTPYWTSLQQN
VAPVLSSSTHSPEERSLRLLGESPTCAVAEDSLSPLLDQLCLRPAPPICTAVASTVPGAA
LCLPPGVLHQEGSVLREETEAWARLHKSRFQDEDLATLGKILCLLDGIMDGQIRNAIATT
TALATAATLDVLIQRCLARRAQRVLCVALGQLDRPLDLADDGRILWLNIRGKDAAIQSMF
HFSTPLPQTTGGFLSLILGLVLPLAYGFQPDMVLMALGPAHGLQNAQAALLAAMLRSPVG
GRILAVVEEESIRLLARSLAQALHGETPPSLGPFSKATPEEIQALMFLKARLEARWKLLQ
VAAPPP

>Bos taurus_HDAC10(ENSBTAP_14602)
MGTALVYHEDMTATRLLWDDPECEIECPERLTTALERLQQHGLKQRCLQLVAREASEAEL
GLVHSPEYVALLQGTQALGTRELQALSKEYDAVYLHPSTFHCARLAVGAALQLVDAVLTG
AVRNGLALVRPPGHHSQRATANGFCVFNNVAIAAKHAQQKHGLRRILIVDWDVHHGQGIQ
YIFEDDPSVLYFSWHRYEHGHFWPCLRESDADAVGRGRGLGFTVNLPWNQVGMGNADYVA
AFLHVLLPLAFEFDPELVLVSAGFDSAIGDPEGQMLATPECFAHLTHLLQVLAGGRVCAV
LEGGYHLESLSQSVCMMVRALLGDPALPLSGPMEPHGSALESLQCVRAAQAPHWVSLQQQ
GAAPVLSPGTPCPEGRPSPLPLGEPQFKAVVTQAAAALSSLLDQLRLHPTPPVRVAVALI
APDTGLALPPGVLCEEGSLPQEETQAWARPHEALAQDGALTALGKVLYLLDRILDGQVSS
GMAATPVPAAAATLDVAVRYGLSHGAQRLLCVAVGQLDRPPGLTDDGRNLWLNIGGEEAA
APSMFHVSVPLPVTTGGFLSCALALVLPLAYSFQPDLVLVALGPAHGLRDPQAALLAALL
RGPAGGRVFALVDEESTPQLATVLARVLNGEAPPSLGPFSMAAPEDTQALMYLRGRLEPR
WKMLQVAAPH

>Canis familiaris_HDAC10(ENSCAFP_979)
MRTALVYHEDMTAARLLWEDPECEIERPERLTAALRRLQQGGLEQRCLQLAPREASEAEL
GLVHSPEYVSLLRGTQALDTQELRALSGQYDAVYFHPSTFHCARLAVGAALQLVDAVLMG
AVHNGLALVRPPGHHSQRAAANGFCVFNNVAIAARHAQQKHGLQRILIVDWDVHHGQGIQ
YIFEDDPSVLYFSWHRYEHGRFWPYLRESDADAVGQGKGRGFTVNLPWNQVPTALPQFDP
ELVLVSAGFDSAIGDPEGQMQATPECFGHLTQLLQVLAGGRVCAVLEGGYHLESLSQSVC
MVVRALLGDPVPPLSGPMEPHRRYGSSALESIQSVRAAQAPHWTSLQQQGQSAPTPRPGT
CSADGRTSLVLPGGPTFKAAEAQASAVLSSLLGQLHLHPTPPVRTAVALTVPDAALGLPP
AVLHQEGSAPQEETRAWARLHEALAQDTAFTALGKVLHLLKGILDGQVSSGVATTPAAAA
MLDVALRCSLSHRAQRVLCVAVGQLDRPPDLANDGRTLWLDIRGKEAAALSPFHVSMPLP
TTGAFLSCVLALVLPLAYGFRPDLVLMVLGPAQGLQEPHAALLAALLRGPAGGRVLVLVE
QVSWAGWTSCGWGGGERPGTAPTSFPGPGTHIPACRHPGPGVAWRRT

>Danio rerio_HDAC10(ENSDARP_109870)
MQKLTMFVIKRRKRTKKKKHDTFEPASFASVTKYILQVLLCCLFHRRQTKSVKMASGSAL
IFDEEMSRYKLLWTDPACEIEVPERLTVSYEALRTHGLAQRCKAVPVRQATEQEILLAHS
EEYLEAVKQTPGMNVEELMAFSKKYNDVYFHQNIYHCAKLAAGATLQLVDSVMKREVRNG
MALVRPPGHHSQRSAANGFCVFNNVAIAALYAKKNYNLNRILIVDWDVHHGQGIQYCFEE
DPSVLYFSWHRYEHQSFWPNLPESDYSSVGKGKGSGFNINLPWNKVGMTNSDYLAAFFHV
LLPVAYEFDPELVIVSAGFDSAIGDPEGEMCALPEIFAHLTHLLMPLAAGKMCVVLEGGY
NLTSLGQSVCQTVHSLLGDPTPRISGLGTACDSALESIQNVRNVQSSYWSSFKHLAQSET
NPKRPRLDATNGGPKESSEPASESNPKKTAQDIVWPEPLKRMPASVRTVVVPPPGVELTL
PKNCQHSGDISESTAKEVQRIRDKHFHDLTDQNILRSLGNIISVLDRMMRSDEVCNGCVV
VSDLSVSVQCALQHALTEPAERVLVVYVGDGELPVKTNDGKVFLVQICTKETEDKCVNRL
SLCLREGESLTAGFMQALLGLILPVAYEFNPALVLGIVGETAAKTGLMTVWGHMTCLIQG
LARGRTLTLLQGYDKDLLELTVSALSGASISPLGPLRALKPEDVEMMEKQRQRLQERWGL
LRCTVSES

>Oryzias latipes_HDAC10(ENSORLP_11723)
NTMGTALIYDEEMTKYKLLWVDPACKIEVPERLTVSHGALVRNGLTDRCICLPVREAVDA
EILLVHSEEYLEAVKQTPHMTLEDLKEFTLQYGDVYFHPNIYHCAKLAVGSALQLVDSVL
MGKVKNGMALVRPPGHHSMRSAANGFCVFNNVAIAAQYAKQKYGVKRILIVDWDIHHGQG
VQYCFEDDPSVLYFSWHRYEHQKFWPNLKDSDYDIVGKGEGAGFNINVPWNKVGMENSDY
LSVFCHVLLPIAYEFCPDLVLVCAGFDSAIGDLEGEMCATPDIFAHLTYLLMNLAEGKLC
AVLEGGYNLTSLAQSVCQTVQTLLGDPLPPLTNLTGPCRSTLESLQCVRAAHRQHWSCLR
HAVDLPTFEISTIRIKSSGEENKDEAEVWEEQKSPEEKIWPEPPKRVSPRVCSAVVLPDG
VVCPDACERLSSSEDLGPHLLTLKKDFLKDADDSAVTALSRVFSLIDKMKNNEIRNGLAL
VGDAAMTMTCVVQHVAAEVDSRVFLVCVGNGNIPGHIIEDGKTLVVQISGEDTEEQGSKY
YVPVCLKKGCTDTSGFAQAMFSLLLPLGYQHNPSLVLLVRMPGSGVCDIMWQQLTALLQS
FAQGHTLVLLQEDDKACVGPTASILLGNPAPPLGQLPASLKEDAEAVERLRSRLQADWNL
LLATGEST

>Takifugu rubripes_HDAC10(ENSTRUP_42353)
MGTALIYDDEMTNYKLLWVDPACNIEVPERLTVCYEALMRTGLADRCVSIPVREATDADI
LLVHSEEYLEAVKKTPYMTLAELMEFTLQYGDVYFHPNIYHCAKLAAGAALQLVDSVMTG
AVRTGMALVRPPGHHSMRSAANGFCVFNNVAIAARYARQKYGLERVLIVDWDIHHGQGVQ
YCFEDDPSVLYFSWHRYEHQKFWPNLRESDYDTVGKEKGAGFNINVPWNRVGMRNSDYLS
VFFHILLPVAYEFCPDLVLVCAGFDSAIGDPEGEMCASPDIFAHLTHLLMNLAGGKLCAV
LEGGYNLTSLPQSVCQTVQTLLGDPAPPPGSLEGPCRSALESLHCVRSAHKPYWSCLKYA
GVISPSFFCTNPLSADLPTSESSSKHDKLAEETKDKAEKETVKEEKVWPEPQKRVCPPVR
AALILPDNVTCPAGCQRFSSTEAREKFSKDGENNSSLTTLPSLVALVDKMENHEIYSGLA
LVQDVSMAMTCTVQHAAALFQRVLIVCVGDMVEQKPGTEDGKTLLVQFSGNISDKPIGKY
HVPVCLKKGCGDVSGFMHAVLSLLLPLGYEYDPNLVLLVRMPGCGIWDSVWQQLTGLLQG
LAQGHTLILMQEEEKPCFVPTVSCLLGNAPPSLASLCAPLPEDTEEVEKLRYHLQADWKL
LQTTGEF

>Gasterosteus aculeatus_HDAC10(ENSGACP_5071)
MKMGTALLYDDEMTKYKLLWTDPVCKIEVPERLTVSHEALLKAGLADRCISVPVREATDA
DILLVHSEEYLEAVKKTPYMTLEDLMEFTLQYGDVYFHPNIYHCAKLAAGATLQLVDSVM
TGKVRNGMALVRPPGHHSMRSAANGFCVFNNVAIAARYAKQKYGIKRVLIVDWDVHHGQG
VQYCFEDDPSVLYFSWHRYEHQKFWPHLRDSDYDCVGKEKGAGFNVNVPWNKVGMKNSDY
LSVFCHVLLPIAYEFSPDLVLVCAGFDSAIGDPEGKMCASPDVFAHLTHLLMNLAGGKLC
AVLEGGYNLTSLHQSVCQTVQTLLGDPAPRPANLDGPCASALESLHCVRSAHRPYWSCLK
HAADLLTSDVSTKGIELTAGGQEKQKAEEERSAESEEWSEPLKRAAPPVRTALVLPDGVV
CPEGCTRFSSSADPSKVNKLRETFLKDSDDSDALTTLSSLTALVQKMEQNEICNGLALVR
DVSMAMMCVVQHAEAAHLDRVLIVCVGDAAVPSQGTDDGTTLLVQFSSEESEGQKRRFHI
PLCLKKGCSDVSGFTQAVLGLVLPLGYEYDPSLVLLVRSPGSGLCDGAWQQLTGLLQGLA
QGHTLVLMQEGEKECVGPTASSLLGVAAASLGRLGAPLQEDVEALEGLRSRLQADWKLLQ
TTGPAAPEPGMKTEADPAEAHQK

>Branchiostoma floridae_(XP_002596886)
MVIDGREQQGSAGGEVEDRLNYIKQQQALQRELLHQHFRQQEEQLARQHQAELQQHLHLQKLQALREQQE
LAQARGKLQEKQSERQKQLLAGKKKENSAMASTEVKEKLQTFILSKKQREAAANSLHQSPSLSMAHWPHG
SLGHMPMSGDLAAAAAYKGHPMLGTYGSNADFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRRDGIGG
SFKTRKPLSNKIHIQVPQSAPGSGPSSPRSSHSNMVIAGNHEESGVQPAVVPGRMVGGNAADFTLYTSPS
LPNISLGLANSSSSAETTQTGEKVVQSALSREAELRAMAAARLGQPLTVVPAREPQPAPRSDEGLGTAGH
SPSNCAASASRPLGRTHSAPLPGTHMHHLQQQVLHPQHYMQALLRQHVVNKQQLGNGDIAKQPRPEPHPE
ETEEELKEHTQVTVKQEPLDSDEENEEEESCRQLDMNIDGTSTHRPLSRAQSSPATYNSVKSVFTTGVVY
DPLMLKHSCSCGNNSYHPEHSGRIQSVWSRLQETGLVNRCERVRSRKATIDELKTCHSEQHVYLYGTNPL
HRQKQDSKKLAGGLQKSFKYLPCGGLGVDADTIWNELHSPSALRMAAGCVIELAFKVAQGELKNGFAVVR
PPGHHAEVDQAMGFCFFNSIAVTARLLVQRLKLNKVLIVDWDVHHGNGTQQMFYEDGQVLYVSLHRWDSG
NFFPGTGAPDECGNGAGLGKNVNISFSGGLEPPMGDAEYMAAFRTVVMPIAVEFSPDLVLVSAGFDTAEG
HAPQLGGYKVTPKCFGHMTKQLMSVAGGRVVLALEGGYDLAAICDCSEMCVQALLGDELPPLPKEIIEQP
PNKNAVTSLEETIRRQTPHWSSLSRYASTVGYSLYEAYEREKEEADTVSALASLSVASAPGVGMPASANS
ERNHKPQPLEDTINGL

>Strongylocentrotus purpuratus_(XP_797761)
MTAAAKSALLYSSPKFRGASWGQGMSEAVGPGSEAVNITSQISNMHLKGDAAPGQMPNASIASQVPADPV
ATDPRVVPQEWVSLQQQQQWQQHMLLAQFKERQAQLVKQHQKQQQELIMVRHVQREQLLEQQRLLEAQQQ
QQQQQQQQQAQKQHLEQLLAKKQSANASTEVKDKLQKFLLNRQQRTDYGGSGPLNHSPPYRHWTPPSSMD
HHSPPHNVSPQFHHQPMGFGQYDSSNFPLRKTASDSNLKVRSRLKEKVTERRTHGSPLLRRREGPNSLKR
KPIIDTSSNSAPGSGPSSPLSAGAAGGGDSPNGLSVAALPEEASSATKMMLKQRLYGVVNDLYSSPSLPN
ISIGIPAANNPQHSPPLGQVKPGLPTASMLGAAPLNPYLPGAPLSLAGINPAHLACMTFQDFQQAQTAAM
SAAQIGIHPKPIRPVTHRPLVRTHSAPLPNNQQVPTSQRPHSMLLSHHHHSQLLQQPHQLLNNLAYQKLL
EERSEERVQEEREQEESESESAAGATASGAPNMPSPSKAKEALKNAIHIKQEPIDFTEEEEEEEEEDDAE
TEISKSREDNLDMLRPSTMTKTGMFGGHRPLMRVRSSPAAAGIPSLSLNHHHHDHNRTKHTFTTGLAYDT
LMLKHQCQCGNNQNHPEHPGRLQSIWARLHERGIVSRCERIRTRKASLEELQSCHSEGYTLFFGTSQTHK
AKLDSRKLALIPKLNFTWLSCGGLGVDTDTVWHDIQSPGAVRIAAGAVIELAFKVATGELKNGFAIVRPP
GHHAETSQAMGFCFFNSIAIAAKQLRLKLKLNKILIIDWDVHHGNSTQKIFYEDPHVLYISLHRHDNGNF
FPGTGAPDESGCGAGLGYNVNIAFHGGLNPPMGDAEYIAAFRSIVLPIAREFSPDVVLVSSGFDAANGHP
NPLGGYKVTPACFSYMTRKVMGLANGRVVLALEGGYDLTAICDASEVCAQTLLGDDPSPLSEDAINGVPN
ANAVECLRRTIEIQSFKEHTLAHEDEYFKTKN

>Drosophila melanogaster_(FBpp0290513)
MSSPDDRIPIHDLPSEAGSDERLLHITPATLTLDFKPHPAVDIDQQIMELKKSQELQKQR
LINSFQEQSKQMELEHKLQLEHKYQFAVNSHGAFQELRNESMVTAAAAAVAQEQHRQQLH
QQQQQHQQQQQQQQHQQQQQQQQARGRDGMKLKQNCSANASPEVKQILNCFILSRKSQAA
ASNGTTTTSPYRNRGVVKSSSGESLPAGTVTSAHPYKIPQPPPSLLKYESDFPLRKTASE
PNLLKIRLKQSVIERKARIGGPAGARRHERLLQAAQRRQQKNSVLTNCNSTPDSGPNSPP
SAAALAVGVVGSRGSPTSAPIQEENEEGSQYQPGQRSSINDLPLFSSPSLPNISLGRPHL
PNSAQAHAQVNAQVAAQAQAQAQAQAQAHAMFAALAAAQGGCGQPGYYNPLGMAFVGRQP
APLAMIPATGIAPQQPSPVVRSASATSTSSSQASLVGDVAPPQAHAASTILPSSSSYMQQ
LGSVAGSGVNLHAAAVAAAAAAAAAAGSLPPTNSHGHGHGSHAHPHPHAHGHGHGHGHGI
YAGHQHNVPITDAQVAQVHLHKQGHRPLGRTQSAPLPLGHPMLTGAVQLNVVQTHYENSE
AERQAYEHQVVNQKVRQTVLTRSGAAAAAAAAAGVSVVREAQLKEEDDDSAAEVMDLTDK
KKPPKTVLTSTIATSTSQNLPEALAAAAAAAAYRAPHNASSNSASATKSGIKLRDQEYLQ
QQREQLLLLQQEEELAKSLMRPLSRTLSSPLVPLGPHGLSQIPDTGQQPAPIATSSSADH
IPPVNLSLPHRQHRQLMSTLYASQLRNHQPSASGSPPHKVTTGLAYDPLMLKHSCICGDN
AQHPEHSGRLQSVWARLNETDLVKRCDRLRARKATQEELQTVHTEAHAMLFGSNQCQLSR
PKLENTLSASFVRLSCGGLGVDLDTTWNEHHTATAARMAAGCVIDLALKTAKGDLRNGFA
VVRPPGHHAEANLAMGFCFFNSIAIAAKLLRQRMPEVRRILIVDWDVHHGNGTQQAFYQS
PDILYLSIHRHDDGNFFPGTGGPTECGSGAGLGFNVNISWSGALNPPLGDAEYIAAFRTV
VMPIARSFNPDIVLVSSGFDAATGHPAPLGGYHVSPACFGFMTRELLQLANGKVVLALEG
GYDLAAICDSAQECVRALLGDPAAPIAKAELERPPCQNAINTLQKTIAIQQTHWPCVRML
EHTVGLSALETLKVEHDESETINAMAGLSMQSMHRTLSRDDSEEPMDQDETK

>Ciona intestinalis_(ENSCINP_16829)
MAVDPAVSALTPNFLAAVYGMGERQYQEKLKRMRHQHEIENQLLMAQFNYQTSNLQHQHQ
LQQHLNHVISKQRERVAEQMAALDQRSELINSVRNKEKNRESAVASNAVKQHLQKFVKCR
QKFKDSHPSMERSPLQWTPSLEGKNGGHEVPAHYSSLLHTQYDFPLRKTASEPNLKLKSR
LKQKLLEDRVERSSPLMPRRGDIKADLANRIKKKINIENVNEQRNSHNSAPNSGPSSPPN
SSNDIKQSTPHMQTETDYYEESNSSGNHDLYSSPSLPNISIGLTNKKSTDRSMLVVSEEL
SKRGTRGSSLSDPMIQSDKPLFQSHAKLHEIDLTQAVQANLLPPHKTVLHAQASTPPGPI
RHSQTTRQHKALSRTQSAPTAASQLQLHILQRRQKMLQQQQKKGLMHGVAEVDSHSYSIL
PTHLETEDGEQWVKRNQYSHAQSTPNQPFIPSNKIASTQAQLVASKPEIPDSMLPMFINK
HSGRFGFLTCPAVARVAIEEGGIAGTRHLPPQSTIPIHSQPSSLSDQNKPRLLRTQSSPA
TSFIKKLPHFKKYRYTTGIAYSPVMLKHGCACRDDHTEHAGRLRAIWERLTKSKLVNDPS
CGGTSGKSSCELLEARKATTDELQLVHTQEHTLRYGTTSLARKELELTSKFIVLPCGGVG
VDNGIDIDTVWNELDTINAARMAVGCTVDITLEVAQNRLKNGFALVRPPGHHAQKDLAMA
FCYFNSVAVAARKLQHECPDTVRRVLIVDWDVHHCNGTQNIFFDDPSVLVISIHRYDSGN
FFPGTGAINECGRGGGLGYNVNIGFSGGLDPPMEDADYLAVFRTIVLPIARQFDPHFVLV
SCGFSAANGHPSTLGGYKLTPNCYGLLTRLLSEVAGGKIVLVLEGGFELEPLCDCTEACV
RTLLGNHEYSNLSMESMERRPSKNAIDTIKNVITIQEKHWKGLDLSSVDMSHLEWLRVSR
ENETCVAMASLSVENKSGNEPNTISEPEAHQQPVDLSNNKSTYQQPHQSADVYFYENCGG
SMSADSSPLDVVGLSTPSSPATKQSDTMDTMNQTSTTESQPMAGV

>Drosophila melanogaster_(FBpp0073826)
MLTKDLNSFSQSPPIVTRRSAQQAKIQTRAMASKSKTGTTGAATAAGGTGSSSGSISGGF
NAADPRKSNKPNAALLEAKRRARNNMLKNQGCGSQESVTDIFQNAVNSKSLVRKPTALIY
DESMSQHCCLWDKEHYECPERFTRVLERCRELNLTERCLELPSRSATKDEILRLHTEEHF
ERLKETSGIRDDERMEELSSRYDSIYIHPSTFELSLLASGSTIELVDHLVAGKAQNGMAI
IRPPGHHAMKAEYNGYCFFNNVALATQHALDVHKLQRILIIDYDVHHGQGTQRFFYNDPR
VVYFSIHRFEHGSFWPHLHESDYHAIGSGAGTGYNFNVPLNATGMTNGDYLAIFQQLLLP
VALEFQPELIIVSAGYDAALGCPEGEMEVTPACYPHLLNPLLRLADARVAVVLEGGYCLD
SLAEGAALTLRSLLGDPCPPLVETVPLPRAELAQALLSCIAVHRPHWRCLQLQQTYDCVE
LQDRDKEEDLHTVLRHWIGGPPPMDRYPTRDTAIPLPPEKLTSNAARLQVLRAETKLSVP
SFKVCYAYDAQMLLHCNLNDTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVC
LAHTRAHVNTVRRLLGREPKELHDAAGIYNSVYLHPRTFDCATLAAGLVLQAVDSVLRGE
SRSGICNVRPPGHHAEQDHPHGFCIFNNVAIAAQYAIRDFGLERVLIVDWDVHHGNGTQH
IFESNPKVLYISLHRYEHGSFFPKGPDGNFDVVGKGAGRGFNVNIPWNKKGMGDLEYALA
FQQLIMPIAYEFNPQLVLVSAGFDAAIGDPLGGCKVTAEGYGMLTHWLSALASGRIIVCL
EGGYNVNSISYAMTMCTKTLLGDPVPTPQLGATALQKPPTVAFQSCVESLQQCLQVQRNH
WRSLEFVGRRLPRDPVVGENNNEDFLTASLRHLNISNDDATAAAGGLAGDRPDCGDERPS
GSKPKVKVKTLSDYLAENKEALEQSEMFAVYPLKTCPHLRLLRPEEAPRSLDSGAECSVC
GSTGENWVCLSCRHVACGRYVNAHMEQHSVEEQHPLAMSTADLSVWCYACSAYVDHPRLY
AYLNPLHEDKFQEPMAWTHGCAWREDGCYATGPDGRDEDDDDDNGAGSSICLRLERNN

>Branchiostoma floridae_(XP_002587576)
MENAEQITFPASDNQPTTEGFDSTTEASSISPSVPENIPRHPTIPPAAEGIVDVVTPNQTKDDSSPEDKN
SEQGKGTGSGKKKGRGSKKKNVTPTGVGRGNTQSLQEAKKKGRKARKAEKELDLLDLSGLSLEERPVPKG
TGVVFDERMADYHCLWEDLSDCKAERPARFTETLTLLRQRGLLDRCVTIPSRPATREEVLSIHSEGLLGK
LESSVTMTTDQLRQLSETFEDIAIHPKSLECARLSAGCTLQLMDQVLTGNVRNGMAVVRPPGHHADRDQS
CGYCLFNNIAIAARQALTKYSLERVLIVDWDVHFGNGTQDLFYDDPRVLFFSIHRYEHMEYWPHMERANY
SFVGRGAGKGYNVNVPWNKIGLGDPDYMAAFQQVLMPMAYEFDPQLVLVSAGFDSAVGDRMGKMVLMPMA
YEFDPQLVLVSAGFDSAAGDPKGEMDTTPSAYAHLLHMLKGTCTSGREVGLVHDEAMMNHVNIWMPGHPE
QPYRIRRIMQALDRHRLQDRCVKLESRLATEEELLYLHTAEHLQLMQETAEMTPRQLNRTQADFNSIFLC
NDTYKSACLAAGCSMNAVEAVATGSVRSAVAVVRPPGHHAEVDKPCGFCIFNSAALAARFAQKRLGVGRV
LILDWDIHHGNGTQHMFVDDPTVLYISIHRYDNGMFFPGSPDADCTVVGSGPGEGFTVNVPWSRGGMGDP
EYMAAFQQVVMPIAYEYSPELVIISAGFDAARGDPLGHCDVTPPGYAHMTHMLSSLAGGRVVLLLEGGYN
LSSISESMSECTKILLGDPCPPLEYSPPCEEAVQSMLSTLHVHQKYWRSLAFQVDVGTKDVCSDEGGDES
STTGTEREPDRYDNGMFFPGSPDADCTVVGSGPGEGFTVNVPWSRGGMGDPEYMAAFQQVVMPIAYEYSP
ELVIISAGFDAARGDPLGHCDVTPPGYAHMTHMLSSLAGGRVVLLLEGGYNLSSISESMAECTKILLGDP
CPPLEYSPPCEEPALMDLNLQMGQLSITGEEKDNQNTAGEIEEKTPTKGTGSDVAAPPVQHHLQLQPPGL
WYFKTV