>Homo_sapiens_DUSP1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------MVMEVGTLDAGGLRALLGE------------
-----------RAAQCLLLDCR----------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------SFFAF
NAG-----HIAGSVNVRFSTIVRRRAKG-AMG-LEHIVP-------NAELRGRLLA------------GAYH------AV
VLLDERSAALDGAKR-----------------------------------------------------------------
-------DGTLALAAG----ALCREARAAQ---VFFLKGG----------------------------------------
-----------------------------YEAFSASCPELCSK-------------------------------------
----QSTPMGLSLP-------------------------------------LSTS-VPDSAESGCSSCSTPLYD------
----------------------------------------QGGPVEILPF-LYLGSAYHASRKDMLDALGITALINVSAN
CP--NHFEGHYQYKSIPVED-----NHKADISSWFNEAIDFI--DSIKNAGGRVFVHCQAGISRSATICLAYLMRTNR--
VKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAP---------------------------HCSAEAGSPAMAVLDR
GT------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------STTTVFNFPV
SIPVHSTNSALSYLQSPITTSPSC--------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------
>Gorilla_gorilla_DUSP1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------AMVMEVGTLDAGGLRALLGE------------
-----------RAAQCLLLDCR----------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------SFFAF
NAG-----HIAGSVNVRFSTIVRRRAKG-AMG-LEHIVP-------NAELRGRLLA------------GAYH------AV
VLLDERSAALDGAKR-----------------------------------------------------------------
-------DGTLALAAG----ALCREARAAQ---VFFLKGG----------------------------------------
-----------------------------YEAFSASCPELCSK-------------------------------------
----QSTPMGLSLP-------------------------------------LSTS-VPDSAESGCSSCSTPLYD------
----------------------------------------QGGPVEILPF-LYLGSAYHASRKDMLDALGITALINVSAN
CP--NHFEGHYQYKSIPVED-----NHKADISSWFNEAIDFI--DSIKNAGGRVFVHCQAGISRSATICLAYLMRTNR--
VKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAP---------------------------HCSAEAGSPAMAVLDR
GT------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------STTTVFNFPV
SIPVHSTNSALSYLQSPITTSPSC--------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------
>Macaca_mulatta_DUSP1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------MVMEVGTLDAGGLRALLRE------------
-----------RAAQCLLLDCR----------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------SFFAF
NAG-----HIAGSVNVRFSTIVRRRAKG-AMG-LEHIVP-------NAELRGRLLA------------GAYH------AV
VLLDERSAALDGARR-----------------------------------------------------------------
-------DGTLTLAAG----ALCREARAAQ---VFFLKGG----------------------------------------
-----------------------------YEAFSASCPELCSK-------------------------------------
----QSTPMGLSLP-------------------------------------LSTS-VPDSAESGCSSCSTPLYD------
----------------------------------------QGGPVEILPF-LYLGSAYHASRKDMLDALGITALINVSAN
CP--NHFEGHYQYKSIPVED-----NHKADISSWFNEAIDFI--DSIKNAGGRVFVHCQAGISRSATICLAYLMRTNR--
VKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAP---------------------------HCSAEAGSPAMAVLDR
GT------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------STTTVFNFPV
SIPVHSTNSALSYLQSPITTSPSC--------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------
>Mus_musculus_DUSP1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------MVMEVGILDAGGLRALLRE------------
-----------GAAQCLLLDCR----------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------SFFAF
NAG-----HIAGSVNVRFSTIVRRRAKG-AMG-LEHIVP-------NAELRGRLLA------------GAYH------AV
VLLDERSASLDGAKR-----------------------------------------------------------------
-------DGTLALAAG----ALCREARSTQ---VFFLQGG----------------------------------------
-----------------------------YEAFSASCPELCSK-------------------------------------
----QSTPTGLSLP-------------------------------------LSTS-VPDSAESGCSSCSTPLYD------
----------------------------------------QGGPVEILSF-LYLGSAYHASRKDMLDALGITALINVSAN
CP--NHFEGHYQYKSIPVED-----NHKADISSWFNEAIDFI--DSIKDAGGRVFVHCQAGISRSATICLAYLMRTNR--
VKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAP---------------------------HCSAEAGSPAMAVLDR
GT------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------STTTVFNFPV
SIPVHPTNSALNYLKSPITTSPSC--------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------
>Gallus_gallus_DUSP1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------MVNLRVCALECEALRGLLQE------------
-----------RAAQCLVLDCR----------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------SFFSF
NAA-----HIRGSCNVRLSTIVRRRAKG-VLA-LEHVVP-------NEELRTRLRQ------------GQVH------TV
VLLDERSADLELPKR-----------------------------------------------------------------
-------DSTLLLALG----TLCREARGAR---ICFLKGG----------------------------------------
-----------------------------YEAFSAACSELCTK-------------------------------------
----PAAPTGLSLP-------------------------------------LSASSAPGSADSGCSSCGTPLYD------
----------------------------------------QGGPVEILPF-LYLGSAYHASRKDMLDALGITALINVSAN
CP--NHFEGHYQYKSIPVED-----NHKADISSWFNEAIDFI--DSVKNDGGRVFVHCQAGISRSATICLAYLMRTNR--
VKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAP---------------------------NCSAEAGSPAMSVLDR
GA------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------STTTVFNFPV
SIPVHTSSSALSYLQSPITTSPSC--------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------
>Anolis_carolinensis_DUSP1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------MVNMQVCALDCETLRGLLES------------
-----------GAA--LVLDCR----------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------SFLAF
NAS-----HVVGSCNVRLSSIVRRRAKG-AVG-LEHLLP-------NEEARARLRQ------------GRYR------AV
VLLDERSADLEAPKR-----------------------------------------------------------------
-------DSTLLLALH----ALAREARQAP---PRLPQGG----------------------------------------
----------------------------GYDAFSSLCPELCTK-------------------------------------
----PSAPKGLTLP-------------------------------------LSSSNAPGSADSNCSSCGTPLYD------
----------------------------------------QGGPVEILPF-LYLGSAYHASRKDMLDALGITALINVSAN
CP--NHFEGHYQYKSIPVED-----SHKADISCWFNEAIDFI--DSVKNDGGRVFVHCQAGISRSATICLAYLMRTNR--
VKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAP---------------------------NCSAEAGSPAMSALDR
G-------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------------TTTVFNFPV
SIPVHTSTSALSYLQSPITTSPSC--------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------
>Danio_rerio_DUSP1_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------MYLELSFCTMVIMEVPTIDSASLRDMLEG------------
-----------DDPDCLVLDCR----------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------SFFSF
SVS-----HISGSSNVRFSTIVRRRARG-GLG-LEHIVP-------NEDTRNRLLS------------GEYQ------SV
VFLDDHSLEMGEVKK-----------------------------------------------------------------
-------DGTLMLAVN----ALCRKQCGAS---VYLLKGG----------------------------------------
-----------------------------FDTFSAEFPEKCTK-------------------------------------
----TVPPQGLSLP-------------------------------------LSSNCHSNTADSSCNTCTTPLYD------
----------------------------------------QGGPVEILPF-LYLGSAYHASRKDMLDMLGITALINVSSN
CP--NHFEDHYQYKSIPVED-----NHKANISSWFNEAIEFI--DSVRNKGGRVFVHCQAGISRSATICLAYLMRTNR--
VKLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLASS--------------------------TCSSEAGSPAIG----
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------KNSTVFNF--
--PVHTAASPLSFLQSPITTSPSC--------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------
>Takifugu_rubripes_DUSP1_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------MVIMEVPTIDCASLRGLLED------------
-----------GVPGCLVLDCR----------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------SFLSF
NSS-----HISGSANVRFSTIVRRRARG-GLG-LEHIIP-------NEDTRSRLLS------------GEYP------SV
VLLDDRSLDSSQAKK-----------------------------------------------------------------
-------DGTLMLAVT----ALCRDPCGVR---VLILKGG----------------------------------------
-----------------------------FEAFSREYPEMCTK-------------------------------------
----PSPPQGLSLP-------------------------------------LSS-SHPESADPSCSPCNTPLYD------
----------------------------------------QGGPVEILPF-LYLGSAYHASRKDMLDMLGITALINVSSN
CP--NHFEGSYLYKSIPVED-----NHKADISSWFNEAIDFI--DSVRNKGGRVFVHCQAGISRSATICLAYLMRTNR--
VKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLASS--------------------------SCSTEAGSPAIG----
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------NGSTVFNFPV
SIPVHASANQLSFLHSPITTSPSC--------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------
>Tetraodon_nigroviridis_DUSP1_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------MVIMEVPTVDCASLRGLLED------------
-----------GAPGCLVLDCR----------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------SFLSF
NSS-----HISGSTNVRFSTIVRRRARG-GLG-LEHIVP-------NEDTRSRLLS------------GEGP------SV
VLLDERSALS-QAKK-----------------------------------------------------------------
-------DGTLMLAVT----ALCRDPCGVQ---VLILKGG----------------------------------------
-----------------------------FEAFSREYPEMCTK-------------------------------------
----PCAPQGLSLP-------------------------------------LSS-SHPESADPSCSPCNTPLYD------
----------------------------------------QGGPVEILPF-LYLGSAYHASRKDMLDMLGITALINVSSN
CP--NHFEDSYLYKSIPVED-----NHKADISSWFNEAIDFI--DSVRNNGGRVFVHCQAGISRSATICLAYLMRTNR--
VKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLASS--------------------------SCSTEAGSPAIG----
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------NSNTVFNFPV
SIPVHASAKQLSFLHSPITTSPSC--------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------
>Gasterosteus_aculeatus_DUSP1_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------MVVMEVPTIDCESLRCLLED------------
-----------DVPGSLVLDCR----------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------SFLSF
NSS-----HISGSTNVRFSTIVRRRARG-GLG-LEHIVP-------NEDTRGRLLS------------GEYQ------AV
VLLDDRSSDLSQAKK-----------------------------------------------------------------
-------DGTLMLAVA----ALCRDRCGAR---VFILKGG----------------------------------------
-----------------------------FEMFSAEYPEACTK-------------------------------------
----PPPPQGLSLP-------------------------------------LSS-SRPESADPNCSPCNTPLYD------
----------------------------------------QGGPVEILPF-LYLGSAYHASRKDMLDMLGITALINVSAN
CP--NHFVDSFLYKSIPVED-----NHKADISSWFSEAIEFI--DSVRNKGGRVFVHCQG-ISRSATICLAYLMRTNR--
VKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLASS--------------------------TCSSEAGSPAIG----
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------NNSTVFNFPV
SIPVHTSAGQLSFLHSPITTSPSC--------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------
>Oryzias_latipes_DUSP1_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------MVIMEVLTVDSASLRALLDR------------
-----------DVPDCLVLDCR----------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------SFLSF
NSS-----HISGSSNVRFSTIVRRRARG-GLG-LEHIVP-------NEDTRNRLLS------------GDYK------SV
VLLDDRSLDLGQVKK-----------------------------------------------------------------
-------DGTLMLAVT----ALCRDPCGAN---VYILKGG----------------------------------------
-----------------------------FDAFSTEYPDMCTK-------------------------------------
----SSPPQGLSLP-------------------------------------LSS-RNPDSAS--YSPCNTPLYD------
----------------------------------------QGGPVEILPF-LYLGSAYHASRKDMLEMLGITALINVSAN
CP--NHFEDSFLYKSIPVED-----NYKADISSWFNEAIEFIA-DSVRNKGGRVFVHCQAGISRSATICLAYLMRTNR--
VKLDEAFEFVKKRRSIISPNFSFMGQLLQFESQVLASS--------------------------TCSSEAGSPAMG----
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------NNGTVFNFPV
SIPVHSSASQLSFLHSPITTSPSC--------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------
>Ciona_intestinalis_DUSP1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------MVSQPISCTQFASVLRG------------
------------ASDYLAIDCR----------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------SFLVF
NQG-----RVRNAINIRSNSILRRRSRG-EMC-IENVIS-------SAEKRKLFSE------------GNIK------TV
IVYDENGDADQQAQK-----------------------------------------------------------------
-------YVQRRTTNT---VLTTLLKHSSGQADIRYLSG-----------------------------------------
----------------------------GFKLFQVDFPELCEG-------------------------------------
----LENTLSFSNEE-------------------------------------------RSPGNETPATPTPIYDQ-----
-----------------------------------------GSPVEILPH-LYLGSAHHASQENELAALGITGVLNASSH
CP--NHFPDRFQYKRIPVED-----NGQADISSWFDEAISFI--NEEKQRGGKVFVHCHAGISRSATICLAYLITCRG--
VSLNDAFRYVKSKRSVISPNFNFMGQLSSLEAKLSRRPVPERIQSVGDIAAHLRKHGETLPMEWTCEADTPETVAPVAAK
PPSPQSR-------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------LYRRRAVTAAIPIQI
LSPLKPANKTAMPEDKRCMTAPVLRTDFAFQFPDK---RDCKCHVALRILHCQQPAFTLST-------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------
>Homo_sapiens_DUSP2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------MGLEAARELECAALGTLLRDPRE---------
------------AERTLLLDCR----------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------PFLAF
CRR-----HVRAARPVPWNALLRRRARGPPAAVLACLLP-------DRALRTRLVR------------GELA------RA
VVLDEGSASVAELRP-----------------------------------------------------------------
-------DSPAHVLLA-----ALLHETRAGPTAVYFLRG-----------------------------------------
----------------------------GFDGFQGCCPDLCS--------------------------------------
----EAPAPALPP---------------------------------------------TGDKTSRSDSRAPVYDQ-----
-----------------------------------------GGPVEILPY-LFLGSCSHSSDLQGLQACGITAVLNVSAS
CP--NHFEGLFRYKSIPVED-----NQMVEISAWFQEAIGFI--DWVKNSGGRVLVHCQAGISRSATICLAYLMQSRR--
VRLDEAFDFVKQRRGVISPNFSFMGQLLQFETQVLCH-------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------
>Gorilla_gorilla_DUSP2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------MGLEAARELECAALGTLLREPRE---------
------------AERTLLLDCR----------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------PFLAF
CRR-----HVRAARPVPWNALLRRRARGPPAAVLACLLP-------DRALRTRLAR------------GELA------RA
VVLDEGSASVAELRP-----------------------------------------------------------------
-------DGPAHVLLA-----ALLHETRAGPTAVYFLRG-----------------------------------------
----------------------------GFDGFQGCCPDLCS--------------------------------------
----EAPAPALPP---------------------------------------------TGDKTSRSDPRAPVYDQ-----
-----------------------------------------GGPVEILPY-LFLGSCSHSSDLQGLQACGITAVLNVSAS
CP--NHFEGLFRYKSIPVED-----NQMVEISAWFQEAIGFI--DWVKNSGGRVLVHCQAGISRSATICLAYLMQSRR--
VRLDEAFDFVKQRRGVISPNFSFMGQLLQFETQVLCH-------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------
>Macaca_mulatta_DUSP2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------DCR----------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------PFLAF
CRR-----HVRAARPVPWNALLRRRARGPPAAVLACLLP-------DRALRTRLGR------------GELA------RA
VVLDEGSASVAELRP-----------------------------------------------------------------
-------DGPAHVLLA-----ALLHETRAGPTAVFFLRG-----------------------------------------
----------------------------GFDGFQGCCPDLCS--------------------------------------
----EAPAPALPPP--------------------------------------------AGSKTSCSDPRATIYDQ-----
-----------------------------------------GGPVEILPY-LFLGSCSHSSDLQGLQACGITAVLNVSAS
CP--NHFEGLFRYKSIPVED-----NQMVEISAWFQEAIGFI--DWVKNSGGRVLVHCQAGISRSATICLAYLMQSRR--
VRLDE---------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------
>Mus_musculus_DUSP2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------MPIAMGLETACELECAALGALLREPRE---------
------------AERTLLLDCR----------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------PFLAF
CRS-----HVRAARPVPWNALLRRRARGTPAAALACLLP-------DRALRARLGR------------GELA------RA
VVLDESSASVAELPP-----------------------------------------------------------------
-------DGPAHLLLA-----ALQHEMRGGPTTVCFLRG-----------------------------------------
----------------------------GFKSFQTYCPDLCS--------------------------------------
----EAPAQALPP---------------------------------------------AGAENSNSDPRVPIYDQ-----
-----------------------------------------GGPVEILPY-LYLGSCNHSSDLQGLQACGITAVLNVSAS
CP--NHFEGLFHYKSIPVED-----NQMVEISAWFQEAISFI--DSVKNSGGRVLVHCQAGISRSATICLAYLIQSHR--
VRLDEAFDFVKQRRGVISPNFSFMGQLLQLETQVLCH-------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------
>Danio_rerio_DUSP2_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------MGIGDPLEISGSELVQILRTPSEL--------
----------FASGGCIVLDCR----------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------PFLGF
SRA-----HILESRNVNWNSMLRRRSK-SSVVSLEWLVA-------DKSLLAQLRN------------GDFS------PV
VVLDENSRSVRDLKS-----------------------------------------------------------------
-------ESLASLLIS-----ALQSEVQSASTHICFLQG-----------------------------------------
----------------------------GFDGFFALYPELCFTAPA----------------------------------
----VLCSNHSTLS---------------------------------------------EPEPVMSGRKTPLYDQ-----
-----------------------------------------GGPVEILPF-LFLGSAHHSSRRETLERNGITAVLNVSSS
CP--NLFEEELQYKTLKVED-----SLAADIRVLFPEAIHFI--DSIKEGGGRVLVHCQAGISRSATICLAYLIHAQR--
VRLDEAFDFVKRRRQVISPNLAFMGQLLQFETDVLCPYSVL---------------ERESSGTAF---------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------
>Takifugu_rubripes_DUSP2_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------ITLRPLEVMASIEPLEITGNELVHLLGSQPDQ--------
----------YPCAGCVVLDCR----------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------PFLDF
SLA-----HIYESRNVNWNSMLRRRSK-SSVVALEWLIP-------DKSLLGRLRR------------AEFS------AV
VVLDEGSRCVKELKP-----------------------------------------------------------------
-------ESVVKMLLS-----ALQNETQ---TQICFLQG-----------------------------------------
----------------------------GFEGFSEAYPDLCC--------------------------------------
----LSAS-EDPAV---------------------------------------------EAEPTGTGRRTPAYDR-----
-----------------------------------------DGPVELLPF-LYLGSALHSSRRETLTAAGITAVLNVSST
CP--NFYEGDFEYLRLTVED-----SLAADIGACFSTAIAFI--DSVKQRGGRVLVHCQAGISRSATICLAYLMHTQR--
VKLDEAFDFVKQRRQVISPNLAFMGQLLQFETDVL---------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------
>Tetraodon_nigroviridis_DUSP2_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------IPEEAGLVSPAKVLC---LKLGEIQRDQ--------
----------SPSAGCVLLDCR----------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------PFLDF
SLT-----HIYESRNVNWNSMLRRRSK-SSVVALEWLIP-------DKSLLGRLRR------------AEVS------AV
VVLDEGSGCVAELKA-----------------------------------------------------------------
-------ESVGKMLLS-----ALHNESQ---SQICFLQG-----------------------------------------
----------------------------GFEGFSEAYPELCY--------------------------------------
----ISAG-QTPTM---------------------------------------------EAEPTGTGRRTPAYDQ-----
-----------------------------------------DGPVELLPF-LYLGSAFHSSRRETLTAAGITAVLNVSST
CP--NFFEGEFRYLQLTVED-----SLATDIRACFSTAIAFI--DSVKQSGGRVLVHCQAGISRSATICLAYLMHTQR--
VKLDEAFDFVKQRRQVISPNLAFMGQLLQFETDVLCQ-------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------
>Oryzias_latipes_DUSP2_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------VMMSNSVLLEITGNELVHILRTPQDQ--------
----------YTSDGCVVLDCR----------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------PFLDF
SLT-----NICESRNVNWNSMLRRRSK-SSVVALEWLIP-------DKALLGRLRA------------GLLS------PV
VVVDERSRCLSDVKP-----------------------------------------------------------------
-------ESVAHMLLS-----ALQNEVQ---AQICFLQG-----------------------------------------
----------------------------GFEGFSEAFPELCH--------------------------------------
----CSASSQLSLM---------------------------------------------EPEPAVTGRSTPAYDQ-----
-----------------------------------------DGPVELLPF-LFLGSAVHSSRREMLTAAGITAVLNVSST
CP--NLYEGEFKYLRLTVED-----TLAADIRACFNTAIAFI--DSVKQSGGRVLVHCQAGISRSATICLAYLMHTQR--
VRLNEAFDFVKQRRNVISPNLAFMGQLLQFETDILCQ-------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------
>Gasterosteus_aculeatus_DUSP2_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------MTSSSEPLEIAGNELVHILRTPRDR--------
----------YCSAGSVVLDCR----------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------PFLDF
AFA-----HICESRNVNWNSMMRRRSK-SSAVALEWLIP-------DKALLGRLRR------------GDFS------PV
VVVDESSRSVAELRP-----------------------------------------------------------------
-------ESVGQMLLT-----ALRYEFH---TQICFLQG-----------------------------------------
----------------------------GFDGFAEAYPELCY--------------------------------------
----SSASDRLPAV---------------------------------------------EPEPAVTGRTTPAYDQ-----
-----------------------------------------GGPVELLPF-LFLGSAVHSSRRETLAAAGITAVLNVSST
CQ--NFYEGDFEYLRLTVED-----NLAADIRACFSTAIAFI--DSVKQSGGRVLVHCQAGISRSATICLAYLMHTQR--
VKLDEAFDFVKRRRQVISPNLGFMGQLLQFETDVLCRG------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------
>Drosophila_melanogaster_DUSP2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------MPETEHETCSKEWLQSQLRSL-----------
-----------DSKDLILLDCR----------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------GSHEY
SES-----HIRGAVNLCIPSIVLRRLAVGK-IDLASTIKSPE-------LKQRIQS-----------------GYKLCWF
ILYNGEGVPGQNQEIAGAG-------------------------------------------------------------
------SLAVAMDSIISILHRRLKQDG----CRVVALQD-----------------------------------------
----------------------------GFNNFRQAFPEWCEDDNQTHS------------KEIESSR----------NV
QTDQLMGLRSLRISTTQS-------------------------------------DSACSSSAESSDCESSSHHHH----
HHSHHNYN---------------------------------EAPVEIIPGLLFLGNATHSCDSEALKKYNIKYVLNVTPD
LPNKFKESGDIKYLQIPITDH---YSQ--DLAIHFPDAIQFIE-EARSASSV-VLVHCLAGVSRSVTVTLAYLMHTRG--
LSLNDAFAMVRDRKPDVSPNFHFMQQLLSFESQLRLRPG-------------------------SRFSCSCIAPDCNCMQ
TTGFMA--------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------------THLANATGV
SPDSGIEFDRWTPSDTGLK-------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------
>Homo_sapiens_DUSP4
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------MVTMEELREMDCSVLKRLMNRDENG--GGAGGS
G--SHGTLGLPSGGKCLLLDCR----------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------PFLAH
SAG-----YILGSVNVRCNTIVRRRAKG-SVS-LEQILP------AEEEVRARLRS------------GLYS------AV
IVYDERSPRAESLRE-----------------------------------------------------------------
-------DSTVSLVVQ----ALRRNAERTD-IC--LLKG-----------------------------------------
----------------------------GYERFSSEYPEFCSK-------------------------------------
----TKALAAIPPP--------------------------------------VPPSATEPLDLGCSSCGTPLHDQ-----
-----------------------------------------GGPVEILPF-LYLGSAYHAARRDMLDALGITALLNVSSD
CP--NHFEGHYQYKCIPVED-----NHKADISSWFMEAIEYI--DAVKDCRGRVLVHCQAGISRSATICLAYLMMKKR--
VRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAT---------------------------SCAAEAASPSGPLRER
GK------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------TPATPTSQFVFSFPV
SVGVHSAPSSLPYLHSPITTSPSC--------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------
>Gorilla_gorilla_DUSP4
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------RVLFSSSRAQPPRFPATMVTMEELREMDCSVLKRLMNRDENG--GGAGGS
G--SHGTLGLPSGGKCLLLDCR----------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------PFLAH
SAG-----YIRGSVNVRCNTIVRRRAKG-SVS-LEQILP------AEEEVRARLRS------------GLYS------AV
IVYDERSPRAESLRE-----------------------------------------------------------------
-------DSTVSLVVQ----ALRRNAERTD-IC--LLKG-----------------------------------------
----------------------------GYERFSSEYPEFCSK-------------------------------------
----TKALAAIPPP--------------------------------------VPPSATEPLDLGCSSCGTPLHDQ-----
-----------------------------------------GGPVEILPF-LYLGSAYHAARRDMLDALGITALLNVSSD
CP--NHFEGHYQYKCIPVED-----NHKADISSWFMEAIEYI--DAVKDCRGRVLVHCQAGISRSATICLAYLMMKKR--
VRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAT---------------------------SCAAEAASPSGPLRER
GK------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------TPATPTSQFVFSFPV
SVGVHSAPSSLPYLHSPITTSPSC--------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------
>Mus_musculus_DUSP4
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------MVTMEELREMDCSVLKRLMNRDENGGGGSAGGN
GSGSHGALGLLSGGKCLLLDCR----------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------PFLAH
SAG-----YIRGSVNVRCNTIVRRRAKG-SVS-LEQILP------AEEEVRARLRS------------GLYS------AV
IVYDERSPRAESLRE-----------------------------------------------------------------
-------DSTVSLVVQ----ALRRNAERTD-IC--LLKG-----------------------------------------
----------------------------GYERFSSEYPEFCSK-------------------------------------
----TKALAAIPPP--------------------------------------VPPSTNESLDLGCSSCGTPLHDQ-----
-----------------------------------------GGPVEILPF-LYLGSAYHAARRDMLDALGITALLNVSSD
CP--NHFEGHYQYKCIPVED-----NHKADISSWFMEAIEYI--DAVKDCRGRVLVHCQAGISRSATICLAYLMMKKR--
VRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLTT---------------------------SCAAEAASPSGPLRER
GK------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------ATPTPTSQFVFSFPV
SVGVHAAPSNLPYLHSPITTSPSC--------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------
>Gallus_gallus_DUSP4
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------