>Homo_sapiens_DKK2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------MA
ALMRSKDSSCCLLL--LAAVLMVESSQIGSSRAKLNSIKSSLGGETPGQAANRSAG------------------------
------------------------------------------------------MYQGLAFGGSKKGKNL----------
---GQAYPCSSDKECEVGRYCHSPHQGSSA--------------------------------------------------
-------------CMVCRRKKKRC-------------------------------HRDGMCCPST---------------
RCNNG-ICIPVTESILT---------------------------------------------------------------
-------------------------------------------------------------------PHIPALDGTRHRD
--------------------------------------------------------------------------------
-------------------------------------------------------RNHGHYSNHDLGWQNLGRPHTKMSH
IK----------------------------------------------------------------GHEGDPCLR-----
SSDCI----------------------------------EGFC-------------------------CARHFWT-----
-------------------------------------------KICKPVLHQ--------------------GEVCTKQ-
RK--------------------------------------------KGSHGLEIFQRCDCAKGLSCKV------------
----WKDA-----------------TYSSKARLHVCQKI-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Gorilla_gorilla_DKK2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----AYPCSSDKECEVGRYCHSPHQGSSA--------------------------------------------------
-------------CMVCRRKKKRC-------------------------------HRDGMCCPGT---------------
RCNNG-ICIPVTESILT---------------------------------------------------------------
-------------------------------------------------------------------PHIPALDGTRHRD
--------------------------------------------------------------------------------
-------------------------------------------------------RNHGHYSNHDLGWQNLGRPHTKMSH
IK----------------------------------------------------------------GHEGDPCLR-----
SSDCI----------------------------------EGFC-------------------------CARHFWT-----
-------------------------------------------KICKPVLHQ--------------------GEVCTKQ-
RK--------------------------------------------KGSHGLEIFQRCDCAKGLSCKV------------
----WKDA-----------------TYSSKARLHVCQKI-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Macaca_mulatta_DKK2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------MA
ASMRCKDSSRCLLL--LAAVLMVESSQIGSSRAKLNSIKSSLGGETPAQAANRSAG------------------------
------------------------------------------------------IYQGLAFGGSKKGKNL----------
---GQAYPCSSDKECEVGRYCHSPHQGSSA--------------------------------------------------
-------------CMVCRRKKKRC-------------------------------HRDGMCCPGT---------------
RCNNG-ICIPVTESILT---------------------------------------------------------------
-------------------------------------------------------------------PHIPALDGTRHRD
--------------------------------------------------------------------------------
-------------------------------------------------------RNHGHYSNHDLGWQNLGRPHTKMSH
IK----------------------------------------------------------------GHEGDPCLR-----
SSDCI----------------------------------EGFC-------------------------CARHFWT-----
-------------------------------------------KICKPVLHQ--------------------GEVCTKQ-
RK--------------------------------------------KGSHGLEIFQRCDCAKGLSCKV------------
----WKDA-----------------TYSSKARLHVCQKI-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Mus_musculus_DKK2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------MA
ALMRVKDSSRCLLL--LAAVLMVESSQLGSSRAKLNSIKSSLGGETPAQSANRSAG------------------------
------------------------------------------------------MNQGLAFGGSKKGKSL----------
---GQAYPCSSDKECEVGRYCHSPHQGSSA--------------------------------------------------
-------------CMLCRRKKKRC-------------------------------HRDGMCCPGT---------------
RCNNG-ICIPVTESILT---------------------------------------------------------------
-------------------------------------------------------------------PHIPALDGTRHRD
--------------------------------------------------------------------------------
-------------------------------------------------------RNHGHYSNHDLGWQNLGRPHSKMPH
IK----------------------------------------------------------------GHEGDPCLR-----
SSDCI----------------------------------DGFC-------------------------CARHFWT-----
-------------------------------------------KICKPVLHQ--------------------GEVCTKQ-
RK--------------------------------------------KGSHGLEIFQRCDCAKGLSCKV------------
----WKDA-----------------TYSSKARLHVCQKI-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Oryctolagus_cuniculus_DKK2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MAGKDSSRCLLL--LAAVLMVESSQLGNSRAKLNSIKSSLGGETPAQAANRSAG------------------------
------------------------------------------------------IYQGLAFGGSKKGKNL----------
---GQAYPCSSDKECEVGRYCHSPHQGSSA--------------------------------------------------
-------------CMVCRRKKKRC-------------------------------HRDGMCCPGT---------------
RCNNG-ICIPVTESILT---------------------------------------------------------------
-------------------------------------------------------------------PHIPALDGTRHRD
--------------------------------------------------------------------------------
-------------------------------------------------------RNHGHYSNHDLGWQNLGRPHTKMSH
IK----------------------------------------------------------------GHEGDPCLR-----
SSDCI----------------------------------EGFC-------------------------CARHFWT-----
-------------------------------------------KICKPVLHQ--------------------GEVCTKQ-
RK--------------------------------------------KGSHGLEIFQRCDCAKGLSCKV------------
----WKDA-----------------SYSSKARLHVCQKI-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Canis_familiaris_DKK2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------MA
AWMRGKDSSRCLLL--LAAVLMVESSQLGGSRAKLNSIKSSLGGETPAQVANRSAG------------------------
------------------------------------------------------TYQGLAFGGSKKGKNL----------
---GQAYPCSSDKECEIGRYCHSPHQGSSA--------------------------------------------------
-------------CMVCRRKKKRC-------------------------------HRDGMCCPGT---------------
RCNNG-ICIPVTESILT---------------------------------------------------------------
-------------------------------------------------------------------PHIPALDGTRHRD
--------------------------------------------------------------------------------
-------------------------------------------------------RNHGHYSNHDLGWQNLGRQHTKMSH
IK----------------------------------------------------------------GHEGDPCLR-----
SSDCI----------------------------------EGFC-------------------------CARHFWT-----
-------------------------------------------KICKPVLHQ--------------------GEVCTKQ-
RK--------------------------------------------KGSHGLEIFQRCDCAKGLSCKV------------
----WKDA-----------------TYSSKARLHVCQKI-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Equus_caballus_DKK2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------MA
ALMRSKDSSRCLLL--LAAVLMVESSQLGSSRAKLNSIKSSLGGETPAQAANRSAG------------------------
------------------------------------------------------TYQGLAFGGSKKGKNP----------
---GQAYPCSSDKECEVGRYCHSPHQGSSA--------------------------------------------------
-------------CMVCRRKKKRC-------------------------------HRDGMCCPGA---------------
RCNNG-ICIPVTESILT---------------------------------------------------------------
-------------------------------------------------------------------PHIPALDGTRHRD
--------------------------------------------------------------------------------
-------------------------------------------------------RNHGHYSNHDLGWQNLGRPHTKMPH
IK----------------------------------------------------------------GHDGDPCLR-----
SSDCI----------------------------------EGFC-------------------------CARHFWT-----
-------------------------------------------KICKPVLHQ--------------------GEVCTKQ-
RK--------------------------------------------KGSHGLEIFQRCDCAKGLSCKV------------
----WKDA-----------------TYSSKARLHVCQKI-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Loxodonta_africana_DKK2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------MA
ALMRGKDSSCCLLL--LAAVLMVESSQLGSSRAKLNSIKSSLGGETPAQAANRSAG------------------------
------------------------------------------------------IYQGLAFGGSKKGKNL----------
---GQAYPCSSDKECEVGRYCHSPHQGSSA--------------------------------------------------
-------------CMVCRRKKKRC-------------------------------HRDGMCCHGT---------------
RCNNG-ICIPVTESILT---------------------------------------------------------------
-------------------------------------------------------------------PHIPALDGARHRD
--------------------------------------------------------------------------------
-------------------------------------------------------RNHGHYSNHDLGWQNLGRPHSKMSH
IK----------------------------------------------------------------GHEGDPCLR-----
STDCI----------------------------------EGFC-------------------------CARHFWT-----
-------------------------------------------KICKPVLHQ--------------------GEVCTKQ-
RK--------------------------------------------KGSHGLEIFQRCDCAKGLSCKV------------
----WKDA-----------------TYSSKARLHVCQKI-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Monodelphis_domestica_DKK2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------MT
LMMWNKESSRCLLL--LAAVLMVESSQLGSSRSKLNSIKSVLGGETPTQATNRSAA------------------------
------------------------------------------------------VYQGLTFGSSKKGKNLGQVGKSSKHN
HQQGEAYPCSSDKECEVGRYCNSPHQGSSA--------------------------------------------------
-------------CLVCRRKKKRC-------------------------------HRDGMCCPGT---------------
RCNNG-ICIPVTESILT---------------------------------------------------------------
-------------------------------------------------------------------PHIPALDGMRHRD
--------------------------------------------------------------------------------
-------------------------------------------------------RNHGHYSHHDLGWQNLGRPHSKMSH
IK----------------------------------------------------------------GHEGDPCLR-----
SSDCM----------------------------------EGFC-------------------------CARHFWT-----
-------------------------------------------KICKPVLHQ--------------------GEVCTKQ-
RK--------------------------------------------KGSHGLEIFQRCDCAKGLSCKV------------
----WKDA-----------------TYSSKARLHVCQKI-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Gallus_gallus_DKK2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------MI
VLMWNK-CSCCLLL--LAAVLIVESSQLDSSSSKVNSIKSTLMGEAPTQATNRSAG------------------------
------------------------------------------------------IHQGLKLASSKKGKMLEQMRKPPKHY
HRQGEVYPCTNDKECEVGRYCHSPHQASSA--------------------------------------------------
-------------CMLCRRKKKRC-------------------------------HRDGMCCPGN---------------
RCNNG-ICVPVTENILT---------------------------------------------------------------
-------------------------------------------------------------------PHIPALDGPR--N
--------------------------------------------------------------------------------
-------------------------------------------------------KKNSHYTSKDLGWQNLGRAQSKLSH
IK----------------------------------------------------------------GHEGDPCLR-----
SSDCI----------------------------------EGHC-------------------------CARHFWT-----
-------------------------------------------KICKPVLHQ--------------------GEVCTKQ-
RK--------------------------------------------KGSHGLEIFQRCDCAKGLSCKV------------
----WKDA-----------------TSSSKSRLHVCQKI-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Taeniopygia_guttata_DKK2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------MI
VLMWNK-CSCCLLL--LAAVLIVESSQLDSSSSKVNSIKSTLMGEAPTQATNRSAG------------------------
------------------------------------------------------IHQGLMLASMKKS-------------
CQSQTAYPCTNDKECEVGRYCHSPHQATSA--------------------------------------------------
-------------CMLCRRKKKRC-------------------------------HRDGMCCPGN---------------
RCNNG-ICIPVTESILT---------------------------------------------------------------
-------------------------------------------------------------------PHIPALEGPR--N
--------------------------------------------------------------------------------
-------------------------------------------------------KKNGHYASKDLGWHNLGRPRSKLSH
IK----------------------------------------------------------------GHEGDPCLR-----
SSDCI----------------------------------EGHC-------------------------CARHFWT-----
-------------------------------------------KICKPVLHQ--------------------GEVCTKQ-
RK--------------------------------------------KGSHGLEIFQRCDCAKGLSCKV------------
----WKDA-----------------TSSSKSRLHVCQKI-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Anolis_carolinensis_DKK2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------MG
VRGGSRGSSPRPLL--FLAALLVAAESSQPEGAQANAIKATLLGEAPTQATNRSTP------------------------
------------------------------------------------------FHQGGAPGSGKKSKLFGPGGKGLKHY
HRQGEAYPCTNDKECEVGKYCHSPHQAISA--------------------------------------------------
-------------CMICRRKKKRC-------------------------------HRDGMCCPGN---------------
RCNNG-ICIPVTESILT---------------------------------------------------------------
-------------------------------------------------------------------PHIPALEVPR--N
--------------------------------------------------------------------------------
-------------------------------------------------------KKNNHYPTKDLGWQNLGKGQTKLTH
LK----------------------------------------------------------------GHEGDPCLR-----
SSDCS----------------------------------EGFC-------------------------CARHFWT-----
-------------------------------------------KICKPVLHQ--------------------GEVCTKQ-
RK--------------------------------------------KGSHGLEIFQRCDCAKGLNCKI------------
----WKDA-----------------TYSSKARLHVCQKI-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Xenopus_tropicalis_DKK2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------MNMV
LLGMNGECCCLLPL--LAAVLMVESSQLDVSSSKMNAIKSVLLVQTPTAATNKSES------------------------
------------------------------------------------------IHHG---VSHKKGKSN----------
---GQAYPCISDKECEVGRYCYSPHQAPSS--------------------------------------------------
-------------CMLCRRKKKRC-------------------------------HRDGMCCPGN---------------
RCNNG-ICIPVAETIMS---------------------------------------------------------------
-------------------------------------------------------------------PHIPALETRP---
--------------------------------------------------------------------------------
-------------------------------------------------------KKNGHISNKDLGWQNLGKHHSKIPL
IK----------------------------------------------------------------GHEGDPCLR-----
STDCI----------------------------------EGHC-------------------------CARHFWT-----
-------------------------------------------KICKPVLHQ--------------------GEVCTKL-
RK--------------------------------------------KGSHGLEIFQRCDCAKGLSCKV------------
----WKDA-----------------TYSSKSRLHICQKI-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Danio_rerio_DKK2_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-MLTVTRSRCCWMLPLIVAFVRMGETQGIESQAQVNSIKS--LEPQP-AAANRSG-------------------------
--------------------------------------------------------ASYSGIPKKSN-------------
-IPAQGYPCSSDKECVVGTYCHSPQHAPSR--------------------------------------------------
-------------CLSCRRRKKRC-------------------------------HRDNMCCPGN---------------
RCSNY-ICIPISESALS---------------------------------------------------------------
-------------------------------------------------------------------SHKSSMD------
--------------------------------------------------------------------------------
--------------------------------------------------------ENNKFSIKEKNWKKNGKAHAKISL
KG-----------------------------------------------------------------HEGDPCLR-----
SSDCS----------------------------------EGYC-------------------------CARHFWT-----
-------------------------------------------KICKPVLRQ--------------------GEVCTKQ-
RK--------------------------------------------KGSHGLEIFQRCDCAKGLACKV------------
----WKDA-----------------TSFSRSRLHVCQRI-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Takifugu_rubripes_DKK2_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------------L
RMLFLTWNRCCVVM-FLVAILNMGTSQVSETRPKANSIKPAGLEDAPTPATNRST-------------------------
--------------------------------------------------------TAHSRITKKYN-------------
-ILKQVYPCSSDKECSLGSYCHSPHHAPSR--------------------------------------------------
-------------CLNCRRRKKRC-------------------------------NRDAMCCPGN---------------
RCSNY-ICVPISESVLS---------------------------------------------------------------
-------------------------------------------------------------------PHISPLD------
--------------------------------------------------------------------------------
--------------------------------------------------------EHNKHPTREHSWRKSGKMHAKHPL
KR-----------------------------------------------------------------HEGDACLR-----
SSDCL----------------------------------EGYC-------------------------CARHFWT-----
-------------------------------------------KICKPVLRQ--------------------GEVCTKQ-
RK--------------------------------------------KGAHGLEIFQRCDCAKGLSCKV------------
----WKDA-----------------TSSTKSRLHMCQKI-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Tetraodon_nigroviridis_DKK2_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------------------FSP
RMFILTWNRCCIVM-FLAAILNMGTSQVSETRPKANSIKPAGLEEVPTPATNRST-------------------------
--------------------------------------------------------TVHSRITKKHN-------------
-ILTQVYPCSSDKECSMGSYCHSPHHAPSR--------------------------------------------------
-------------CLNCRRRKKRC-------------------------------NRDAMCCPGN---------------
RCSNY-VCIPISESVLS---------------------------------------------------------------
-------------------------------------------------------------------PHISPLD------
--------------------------------------------------------------------------------
--------------------------------------------------------EHNKHSTKEHSWRKSGKMHAKHPL
KT----------------------------------------------------------------GHEGDACLR-----
SSDCL----------------------------------EGYC-------------------------CARHFWT-----
-------------------------------------------KICKPVLRQ--------------------GEVCTKQ-
RK--------------------------------------------KGAHGLEIFQRCDCAKGLSCKV------------
----WKDA-----------------TSSTKSRLHMCQKI-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Gasterosteus_aculeatus_DKK2_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------LGSV
WMLVLTWDRCCALM-VLVATLRTGTTLLSEAHPKANLIKPALSGGTPTPATNLSD-------------------------
--------------------------------------------------------AVHLGITKKHYT------------
-LAQQVYPCSNDKECSVGSYCHSPQQAPSR--------------------------------------------------
-------------CLSCRRRKKRC-------------------------------HRDAMCCPGN---------------
RCSNY-MCVPISESVLS---------------------------------------------------------------
-------------------------------------------------------------------PHIPALD------
--------------------------------------------------------------------------------
--------------------------------------------------------EHNKLSNKDHGWRKSGKGHAKHSL
KG-----------------------------------------------------------------HEGDPCLR-----
SSDCS----------------------------------EGYC-------------------------CARHFWT-----
-------------------------------------------KICKPVLRQ--------------------GEVCTKQ-
RK--------------------------------------------KGSHGLEIFQRCDCAKGLSCKV------------
----WKDA-----------------TSSSKSRLHMCQKI-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Oryzias_latipes_DKK2_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------------------VVS
RMLATTWNRCCVLM-FLIVSVRT---DASEGRPKENSIKSGLIEEKPTAATNRSAG------------------------
------------------------------------------------------LVSVTQIHGFCKGH------------
-GAEQVYPCSNDKECSVGSYCHSPQQSPSR--------------------------------------------------
-------------CLSCRRKMKRC-------------------------------NRDSMCCPGN---------------
RCSNY-ICVPVFESVLS---------------------------------------------------------------
-------------------------------------------------------------------PHIPALD------
--------------------------------------------------------------------------------
--------------------------------------------------------EHSKHSTKYHSWRKKGKAQAKHSL
KG-----------------------------------------------------------------HEGDPCLR-----
SSDCS----------------------------------EGYC-------------------------CARHFWT-----
-------------------------------------------KICKPVLRQ--------------------GEVCTKQ-
RK--------------------------------------------KGSHGLEIFQRCDCAKGLSCKV------------
----WKDA-----------------TSLSKSRLHMCQKI-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Homo_sapiens_DKK4
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------MVAAVL----LGLSWLCSPLGALVLDFNNIRSSADLHGARKGS-----------------------------
--------------------------------------------------------------------------------
-------QCLSDTDCNTRKFCLQPR-DEK-PF------------------------------------------------
-------------CATCRGLRRRC-------------------------------QRDAMCCPGT---------------
LCVND-VCTTMEDATPI---------------------------------------------------------------
-------------------------------------------------------------------LERQLDEQDGTHA
--------------------------------------------------------------------------------
-------------------------------------------------------EGTTGHPVQENQPKRKPSIKKSQGR
KG----------------------------------------------------------------QE-GESCLR-----
TFDCG----------------------------------PGLC-------------------------CARHFWT-----
-------------------------------------------KICKPVLLE--------------------GQVCSRRG
HK--------------------------------------------DTAQAPEIFQRCDCGPGLLCRS------------
----QLTS-----------------N-RQHARLRVCQKIEKL--------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Gorilla_gorilla_DKK4
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------MVAAVL----LGLSWLCSPLGALVLDFNNIRSSADLHGARKGS-----------------------------
--------------------------------------------------------------------------------
-------QCLSDTDCNTRKFCLQPH-NEK-PF------------------------------------------------
-------------CATCRGLRRRC-------------------------------QRDAMCCPGT---------------
LCVND-VCTTMEDATPI---------------------------------------------------------------
-------------------------------------------------------------------LERQLDEQDGTHA
--------------------------------------------------------------------------------
-------------------------------------------------------EGTTGHPVQENQPKRKPSIKKSQGR
KG----------------------------------------------------------------QE-GESCLR-----
TFDCG----------------------------------PGLC-------------------------CARHFWT-----
-------------------------------------------KICKPVLLE--------------------GQVCSRRG
HK--------------------------------------------DTAQAPEIFQRCDCGPGLLCRS------------
----QLTS-----------------N-QQHARLRVCQKIEKL--------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------