>Homo_sapiens-WISP1(ENSP_250160)
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----------------------------MRWFLPWTLAAVTAAAASTVLATALSPA-PTTMDFTPAPLEDTSSRPQFCKW
PCECPPSPP-----RCPLGVS------------------------LITDG---CEC---------------CKMCAQQLG
DNCTEA---AICDPHRGLYCDYSGDRPRYAIGVCA-Q----------VVGVGCVLDGVRYNNGQSF--------------
-QPNCKYNCTCIDGA-------VGCTP-------LCLRVRPP--------------------------------------
-RLWCPHPRRVSIPGHC-------CEQWVCEDDAKRPRKTAPRDTGA---------------------------------
--------------------------FDAVGEVEAWHRNCIAYTSPWSPCSTSCGLGVSTRISNVNAQCWPEQESR----
--------------------------LCNLRPCDVDIHTLIKA-------------------GKKCLAVYQPEASMNFTL
AG------------------------------CISTRSYQPKYCGVCMD-------------------------------
NRCCIPYKSKTIDVSFQCPDGLGFSRQVLWINACFCNLSCRNPNDIFADLESYPDFSEIAN-------------------
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>Macaca_mulatta-WISP1(ENSMMUP_13337)
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----------------------------MRWFLPWMLAAVTAAATSGVLATALSPA-PTTMDFTPAPLEDTSSRPQFCKW
PCECPPSPP-----RCPLGVS------------------------LITDG---CEC---------------CKMCAQQLG
DNCTEA---AICDPHRGLYCDYSGDRPRYAIGVCA-Q----------VVGVGCVLDGVRYNNGQSF--------------
-QPNCKYNCTCIDGA-------VGCTP-------LCLRVRPP--------------------------------------
-RLWCLNPRRVSIPGHC-------CERWVCEDDARRPRKTAPRDTGA---------------------------------
--------------------------FDAVGEIEPWHRNCIAYTSPWSPCSTSCGLGVSTRISNVNAQCWPEQESR----
--------------------------LCNLRPCDVDIRTLIKA-------------------GKKCLAVYQPEASMNFTL
AG------------------------------CISTRSYQPKYCGVCRD-------------------------------
SRCCIPYKSKTINVSFQCPDGLGFSRQVLWINACFCNLSCRNPNDIFADLESYPDFSEIAN-------------------
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>Mus_musculus-WISP1(ENSMUSP_5255)
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----------------------------MRWLLPWTLAAVAVLRVGNILATALSPT-PTTMTFTPAPLEETTTRPEFCKW
PCECPQSPP-----RCPLGVS------------------------LITDG---CEC---------------CKICAQQLG
DNCTEA---AICDPHRGLYCDYSGDRPRYAIGVCA-Q----------VVGVGCVLDGVRYTNGESF--------------
-QPNCRYNCTCIDGT-------VGCTP-------LCLSPRPP--------------------------------------
-RLWCRQPRHVRVPGQC-------CEQWVCDDDARRPRQTALLDTRA---------------------------------
--------------------------FAASGAVEQRYENCIAYTSPWSPCSTTCGLGISTRISNVNARCWPEQESR----
--------------------------LCNLRPCDVDIQLHIKA-------------------GKKCLAVYQPEEATNFTL
AG------------------------------CVSTRTYRPKYCGVCTD-------------------------------
NRCCIPYKSKTISVDFQCPEGPGFSRQVLWINACFCNLSCRNPNDIFADLESYPDFEEIAN-------------------
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>Rattus_norvegicus-WISP1(ENSRNOP_9673)
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----------------------------MRWLLPWTLAAVAVLMVGNILATALSPT-PTTMTFTPAPLEETITRPEFCKW
PCECPQAPP-----RCPLGVS------------------------LITDG---CEC---------------CKICAQQLG
DNCTEA---AVCDPHRGLYCDYSGDRPRYAIGVCA-Q----------VVGVGCVLDGVRYTNGESF--------------
-QPNCRYNCTCIDGT-------VGCTP-------LCLSPRPP--------------------------------------
-RLWCRQPRHVRVPGQC-------CEQWVCDDDARRPRQTALLDTRA---------------------------------
--------------------------FAASGAVEQRYENCIAYTSPWSPCSTTCGLGISTRISNVNARCWPEQESR----
--------------------------LCNLRPCDVDIRPHIKA-------------------GKKCLAVYQPEEATNFTL
AS------------------------------CVSTRTYQPKYCGVCTD-------------------------------
NRCCIPYKSKTISVDFQCPEGPGFSRQVLWINACFCNLSCRNPNDIFADLESYPDFAEIAN-------------------
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>Canis_familiaris-WISP1(ENSCAFP_1594)
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----------------------------MRWFLPWTLAAVTAAAA-----TAFPPA-PTAMAFTPVPLEDTSSRPQFCKW
PCECPPSPP-----RCPLGVS------------------------LITDG---CEC---------------CKMCAQQLG
DNCTEA---AICDPHRGLYCDYSGDRPRYAIGVCA-Q----------VVGVGCVLDGVRYTNGQSF--------------
-QPNCKYNCTCVDGA-------VGCTP-------LCLRARPP--------------------------------------
-RLWCHRPRRVSIPGRC-------CQQWVCDHDARRPRKTAQRHTGA---------------------------------
--------------------------LAATGEVEPWHRNCIAYTSPWSPCSTTCGLGVSTRISNANSRCWPEQESR----
--------------------------LCNLRPCDVDIRLHIKE-------------------GKKCLAVYQPEAPMNFTL
AG------------------------------CSSTRSYRPKYCGVCTD-------------------------------
DRCCIPYKSKTIDVSFQCPDGPGFSRQILWINACFCNLSCRNPNDIFADLESYPDFSEIAD-------------------
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>Felis_catus-WISP1(ENSFCAP_5858)
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---------------QRLLSPLLVPGDMRELLLSTLLGAALAQ---FCCRAQGGGPSDTPPEGRPGETSEVHQRKQFCHW
PCQCPRQKP-----SCPPGVS------------------------LLRDG---CGC---------------CKVCARQAG
DMCNEA---DLCDPHKDLYSYYSANMIR---GIGEY-----------LIAVGCEFNRVHYHNGQVF--------------
-QPNPLFSCLCVSGA-------IGCTP-------LFIPKPADG-------------------------------------
---HCSGAKGRKKSDQS------NCGLGPFQQQLSTSYKTMPAYRNL---------------------------------
--------------------------------PLIWKRKCLVQATKWTPCSRTCGMGISDRVTNENSNCEMRKEKR----
--------------------------LCYIQPCDSNISKRIK--------------------------------------
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>Loxodonta_africana-WISP1(ENSLAFP_2373)
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---------------------------------------------------ALSPA-PTAMAFTPAPLEDTSSRPQFCKW
PCECPPSPP-----RCPLGVS------------------------LITDG---CEC---------------CKTCAQQLG
DNCTEA---AICDPHRGLYCDYSGDRPRYAIGVCA-Q----------VVGVGCVLDGVRYNNGQSF--------------
-QPNCRYNCTCIDGD-------LGCTP-------LCLRARPP--------------------------------------
-RLWCRHPRRVHVPGRC-------CEQWVCDDDTRKPRKTAPRDTGA---------------------------------
--------------------------LVAMGEVEPWHRNCIAYTSPWSPCSTSCGLGISTRISNANARCWPEQESR----
--------------------------LCILRPCEVDIRSLIKA-------------------GKKCLAVFQPEAPMTFTL
GG------------------------------CTSTRSYRPKYCGVCTD-------------------------------
NRCCIPYKSRTIDVPFQCPDGPGFSRQVLWINACFCNLRCTNPNDIFAHLESYPDFSEIAN-------------------
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>Pteropus_vampyrus-WISP1(ENSPVAP_1334)
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---------------------------------------------------GLSPA-PTAMAFTPAPLEDASSRPQFCKW
PCACPPSPP-----RCPLGVS------------------------LITDG---CEC---------------CKMCAQQLG
DNCTEA---AVCDPHRGLYCDYSGDRPRYAIGVCA-Q----------VVGVGCVLDGARYDNGQSF--------------
-QPNCKYNCTCVDGA-------VGCTP-------LCLRARPP--------------------------------------
-RLWCLRPRRVSLPGRC-------CEQWVCEDQAGRPRKTAPRHAGA---------------------------------
--------------------------AAAVGEAEAWPRNCLAYTSPWSPCSTSCGLGISTRVSNVNTRCWPEQESR----
--------------------------LCSLRPCDADIHLHIKE-------------------GKKCLAVYQPEAPMNFTL
AG------------------------------CVSTRSYRPKYCGVCTD-------------------------------
NRCCVPYKSKTINVSFQCPDGPGFSRQVLWINACFCNLTCRNPNDIFADLDSYPDFSEIAN-------------------
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>Monodelphis_domestica-WISP1(ENSMODP_3...
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-----------------------------------------ALIQNS-----------TVMPPTSVPAEDTSSRPQFCKW
PCECPPTAP-----RCPPGIS------------------------LITDG---CEC---------------CKVCAQQLG
DNCTEA---ATCDPHRGLYCDYSGDGPRYAIGVCARK----------MVGVGCVLDGVRYRNGQSS--------------
-QPNCKFNCTCINGA-------VGCIP-------LCTNSRAP--------------------------------------
-RLWCPNPKKIKMAGRC-------CEQWICD-DSRKPRKTLPRHISP---------------------------------
--------------------------AASEGDTESWQKNCIVHTSSWSPCSRSCGMGISTRISNNNAQCQLSKERR----
--------------------------LCNLRPCEVDITQHIKP-------------------GKKCLAVYQAELPMNLTI
SG------------------------------CVSTNSYRPKYCGICTD-------------------------------
NRCCTPYKSKTIVVNFQCPDGPGFSWKLMWINACFCNLSCRNPNDIFADLEQYHDYAEIAN-------------------
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>Ornithorhynchus_anatinus-WISP1(ENSOAN...
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----------------------------LPWLLPWLLAAATVRSGVMQVSGWLARIRPSSPVSVPSPRLSSGARTQYCKW
PCECPATAP-----RCAPGVS------------------------LVTDG---CEC---------------CPVCARQLG
ATCDEA---APCDRHRGLYCDYSTDSPRYEIGVCA-H----------VVGVGCVLDGVRYRNGQSF--------------
-QPNCKYNCTCINGA-------VGCVP-------LCLSSRPP--------------------------------------
-LVWC-------------------CDRWVCD-DAKKLRRASPRHVPA---------------------------------
--------------------------PAYEGDGGLGQHNCMSYTSPWSLCSRSCGMGISTRISNANERCQLTTESR----
--------------------------LCNLRPCQEGIVQHIKP-------------------GKKCLAVHRPEEPRNFTI
SG------------------------------CVSRNTYRPKFCGVCTD-------------------------------
GRCCTPYKSKTIDVIFVCPDGPGFSRKVMWINACFCHLSCKNPNDIFADLEHYHDYSEIAD-------------------
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>Gallus_gallus-WISP1(ENSGALP_26101)
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-----------------------------------------AIAQTS-----------TTMTPTIPAAKEAYTRTQYCKW
PCECPKSPP-----RCSIGVS------------------------LVTDG---CDC---------------CKMCAKQRG
ENCTEA---DTCDFHRGLYCDYSGDRPRYEIGVCS-Q----------IVGVGCVLNGVRYNNGDTF--------------
-QPNCKYNCTCINGA-------VGCIP-------MCTNSRPP--------------------------------------
-LVWCPNPKLIKMAGKC-------CEQWVCD-DSKKIRKTSPRHISS---------------------------------
--------------------------AAYEGEDEAWQKNCIVHTSPWSPCSKTCGLGISTRISNDNDQCRLLKESR----
--------------------------LCNMRPCEVDITKHIKP-------------------GKKCLAVYRTNEPMNYTI
SG------------------------------CMSKSPYRPKYCGICTD-------------------------------
NRCCTPYKSKTIEVRFECPDGTEISWKIMWINACFCNLNCKNPNDIFADLAHYHDYSEIAN-------------------
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>Taeniopygia_guttata-WISP1(ENSTGUP_12943)
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----------------------------MRWLLPWILAAS-SILQVSLETAGESSA-HVSLQRSPSPTTETYTRTQYCRW
PCECPRSPP-----RCAVGVS------------------------LVTDG---CDC---------------CKTCARQRG
ESCTEA---DTCDFHRGLYCDYSGDRPRYEIGVCA-Q----------IVGVGCVLNGVRYKNGETF--------------
-QPNCKYNCTCINGA-------VGCVP-------MCTNSRPP--------------------------------------
-LVWCPNPKLIKMAGKC-------CEQWVCD-DSRKIRKTSPRHISS---------------------------------
--------------------------AAYEGEDEAWQKNCIVHTSPWSPCSKTCGLGISTRISNDNEQCRLLKESR----
--------------------------LCNMRPCEVDITQHIKP-------------------GKKCLAVYRANEPMNYTI
SG------------------------------CVSKSSYRPKYCGVCTD-------------------------------
NRCCTPYKSKTIEVRFQCPDGTEFSWKIMWINACFCNLNCRNPNDIFADLAHYYDYSEIAN-------------------
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>Xenopus_tropicalis-WISP1(ENSXETP_24033)
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---------------------------------------------------------------------------QFCKW
PCDCPQVPP-----ACPAGVS------------------------LLTDG---CDC---------------CKTCAKQRG
ENCTEA---DTCDTHKGLYCDYSGDSPRYEVGVCG-Q----------MTGVGCVLNGIRYVNGQSF--------------
-QPNCKYNCTCVNGD-------VGCVP-------LCTNSRPP--------------------------------------
-LVWCQNPKRVKMTGKC-------CEQWICD-DFKRVRKTSPRHIASP--------------------------------
-----------------------AS-VAYGGESESWHNNCIVQTTSWSPCSKTCGLGISTRISNENDKCRLRKERR----
--------------------------LCDMRPCDVDITQHIRT-------------------GKKCLSVYREAEPKNFTI
SG------------------------------CLSKRPYRPKYCGVCTD-------------------------------
DRCCIPYKSKTIQVEFECPDGSGFTWNVMWINACFCNLSCRKPNDIFADLQSYHDYTEIV--------------------
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>Anolis_carolinensis-WISP1(ENSACAP_11426)
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------------------------------------------------------------------------TRTQYCKW
PCECPKTPP-----VCPAGTS------------------------LLTDG---CEC---------------CKMCAKQIG
ENCTEA---DICDVHRGLYCDYSRDRPRYEIGVCA-Q----------MVGVGCLLNGIRYKNGESF--------------
-QPNCKYNCTCINGA-------VGCTP-------LCTDSKPP--------------------------------------
-LVWCPNPRQIKMTGQC-------CEQWVCD-YSKKIRKTSPRHISS---------------------------------
--------------------------AVYEGEIETWQKNCILHTSFWSPCSKTCGMGISTRISNDNDQCRLMKESR----
--------------------------LCNLRPCEEDIIKHIKP-------------------GKKCLAVYRRDEPMNYTL
SG------------------------------CTSETTYRPKYCGVCTD-------------------------------
NRCCTPYKSKTIEVNFQCPDGTGFIRKTMWINACFCNLSCKNPNDIFADLAHYHDYSEIAN-------------------
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>Danio_rerio-WISP1(ENSDARP_99684)
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----------------------------MWRLLSWILLTSS---LHQASFHNSTD------SPPMTTELDPYNRNRYCKW
PCKCPKSAL-----VCPHGVS------------------------LLTDG---CDC---------------CKACAKQAG
ETCNER---DICDYHKGLYCDYSADKPRYEKGVCA-Y----------VMGTGCEYNGVIYRNGQSF--------------
-QPNCKYRCLCVNGA-------IGCVP-------LCTDSLPP--------------------------------------
-RVWCQSPKRVKIPGQC-------CEKWICE-ESRKPRKTNPRHAPAE--------------------------------
-----------------------VS------ANDIWHNNCIAQTTPWSPCSKTCGRGISLRISNENAGCVMEKESR----
--------------------------LCNLRPCEVDITKHFRP-------------------GKKCLNIYREPEFQNFTI
SG------------------------------CVSKKPYWPKYCGVCTD-------------------------------
ERCCIPYKSKTIEVEFECPDGALLTWKYMWINACFCNLSCRNPNDIFADLEQYYEFNEIVN-------------------
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>Danio_rerio-WISP1(ENSDARP_70978)
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----------------------------MSWILMWSLLSACAPQIHSASAQDSSNL----LSTEEPITPQPYNRSQYCQW
PCKCPKTPP-----MCPPGVS------------------------LLMDG---CDC---------------CRACAKQVR
EACNEK---ENCDHHRGLYCDYSADKPRYEKGVCA-F----------LPGTGCEHNGVIYRNGQSF--------------
-QPNCKYQCLCVNGA-------IGCVP-------LCNESQPP--------------------------------------
-RVWCQNPQRVKVHGQC-------CELWICD-ESRRGRKTAPRHTMAA--------------------------------
-----------------------LSS-----VKKNWHKNCVAQTTSWSPCSKTCGRGVSLRITNNNKKCEMVNESR----
--------------------------LCNIRPCNVDITKHIKP-------------------GKKCLNIYRAEKPQNFTI
SG------------------------------CTSTNTYRPKYCGVCTD-------------------------------
ERCCIPYKSKTIEVDFQCPNGPGFTWQVMWINACFCNLSCKNPNDIFTDLEQYHEKREI---------------------
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>Oryzias_latipes-WISP1(ENSORLP_4375)
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----------------------------MRALLLWILTAAGIQQAYALNSTAMPL-----STAFTPPPTDAYNRTQYCKW
PCECPEVPP-----KCPPGVS------------------------LLTDG---CEC---------------CKACARQVG
EVCNEA---DTCDYHKGLYCDYSSDKPRYEKGVCA-Y----------MVGTGCEHNGVIYRNGQSF--------------
-QPSCKYQCVCVNGA-------IGCVA-------LCSESQPP--------------------------------------
-RVWCQNPRRIKVRGQC-------CEKWICD-EPRRGRKAAPRHAVEG--------------------------------
-----------------------KHTFLYLSKNRSWDNNCISQTTSWSPCSKTCGRGLSLRISNANDQCQMVKESR----
--------------------------LCNLRPCEVDITNHIKP-------------------GKKCLNIYREDQPLNLTL
SG------------------------------CTSKKQYRPKYCGVCTD-------------------------------
ERCCIPYKSKTIDVEFECPNGAGFTWKMMWIQACFCNLSCRNPNDIFAELENYYGYPEVID-------------------
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>Takifugu_rubripes-WISP1(ENSTRUP_26949)
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----------------------------MSWLLWWIVTAAGIQQAFSQNSTAMSP--ATTTPSITTAAPETYNRTQYCKW
PCECASVTP-----TCPLGVS------------------------LLMDG---CDC---------------CKTCARQVG
EVCNEA---DTCDYHKGLYCDYSSDMPRYEKGVCA-Y----------MAGSGCEHDGVIYRNGQSF--------------
-TPSCKYQCVCVNGA-------IGCVG-------LCTESQPP--------------------------------------
-RVWCQTPRRVKVPGQC-------CEKWICD-EPRRGRKTAPRHAIEG--------------------------------
-----------------------PAAP---AETRSVHKNCISQTTSWSPCSKSCGRGLSLRVSNANERCELVKESR----
--------------------------LCNLRPCEVDITHYIKP-------------------GKKCLNIYREDLPSNFTL
SG------------------------------CTSKKLYRPKYCGVCTD-------------------------------
ERCCIPYKSKTIDIEFECPNGTSFTWKMLWIQACFCNLSCRNPNDIFTELENYYGYSEIVN-------------------
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>Tetraodon_nigroviridis-WISP1(ENSTNIP_...
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----------------------------MSWLLLWILTAAGIQQVGTKASPASSHN-LTAVPAVASAAPDAHSRTQYCKW
PCVCPDAPP-----TCPPGVS------------------------LLVDG---CDC---------------CKTCARQVG
EGCDEA---ATCDHHRGLYCDYSADKPRYEKGVCA-Y----------MAGSGCEHDGVIYRNGQSF--------------
-APSCKYQCVCVNGA-------IGCVG-------LCAESQPPP-------------------------------------
-RVWCQAPRRVKVPGQC-------CERWICD-EARRGRKTAPRHAIE---------------------------------
------------------------AAP---AETRSWHRNCIPQTSSWSPCSRSCGRGLSLRVSNANERCELVKESR----
--------------------------LCNLRPCEVNITGYIKP-------------------GKKCLNIYREELPSNLTI
SG------------------------------CTSKRPYRPKYCGVCTD-------------------------------
ERCCIPYKSRTVEVEFQCPNGTGFSWKMLWIQACFCNLSCRNPNDIFTELDSYYGYSEIVN-------------------
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>Gasterosteus_aculeatus-WISP1(ENSGACP_...
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----------------------------MTWLLVWILTAAGIQQAHSQNSTVMPP-----ATAATSTDAEPYNRTEICKW
PCVCPEVAP-----SCPPGVS------------------------LFLDG---CEC---------------CKACARQVG
EVCNEA---DTCDYHKGLYCDYSSDKPRYEKGVCA-Y----------LGGTGCEHDGVIYRNGQSF--------------
-KPSCKYQCVCVDGA-------IGCVA-------LCTESQPP--------------------------------------
-RVWCQTPRRVKVRGQC-------CEQWICD-EPKRGRKTAPRHAVEA--------------------------------
-----------------------SP-----AETRSWHKNCITQTTSWSPCSKSCGRGVSLRVSNANDQCELVKESR----
--------------------------LCNLRPCEVDITKHIKP-------------------GKTCLNIYREEEASHLTI
SG------------------------------CTSRKQYRPKYCGVCTD-------------------------------
ERCCIPYKSKTIDVEFECPNGSAFTWQMLWVQACFCNLSCRNPNDIFAGLENYYGYPEVMN-------------------
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>Apis_mellifera-WISP1(XP_392489.3)
MSLAVTRWPLEELASAGLRGKDHDARERVVPLVVSNGSSEGRVERGGGHEHGGPLKEGLEQPSSALLLPGRGVDRRDDRC
EGIERCAEDVGGEEATDAGRRATVDEQSSRGVIVGGWSKGREASRGEDRGGGAASSSEAPVLVHRWRDQQAAALDLHSVG
GESGGSEVVRSKARARNGCPPAAVVESGLVGEETLLERRGVCSAQRQSRGSSSGGISGRHHAENARRGIAAAAAAATTAP
NNRSCRVHGRRRDRSRGKATEQRHPVENTRDLTSNEYECSVIRLEQDPILEPVRILGCPPSEGLEISSFLEPAPSYVYQG
INVGRLAGNEAACFSLYDPNNILPKSRAGSIAKILEGPNRAVKDINRKVLAMARAMTPAWSLRLLGVSCGSVVCAWGLLL
ILSVLGGGASHGTALGSFGLGSLSGAMEDMNSARCPWLCTCTGQEVDCSHRGLTQIPGDLVTFLVAEKLDLQGNNISVIF
KTDFEDMATLHVLWLSNNQIHTIERGAFQDLVGVEKLDLSHNQIATIGPKTLRGISSLKYLLLDNNVLTCIDEASIRELK
DLEILMLNNNKLTTLGKEMLNGFSHLRTLKLVDNPLSCDCHLAWLSRHLKSYPRLGQHTKCASPIHLKDRNIADVQEHEF
KCSGPVERTGSECSAEPQCPHPCRCADGIVDCRENSLTKVPTHLPEDTTELRLEQNRITEIPPKAFSPYRKLRRIDLSNN
QIKKVAADAFHGLKSLESLVLYGNKITELPSGLFQGLTNLQLLLLNANEISCIRTDLFRDLTSLTLLSLYDNNIRSLANG
TFANLRSIETLHLARNPFICDCNLRWLNAYLHAHPIETSGAKCESPKRAQKRKIDSMRDDKFKCKGDEELLTKRAGECIL
PGECPDPCVCNGATVDCSNKKLTSIPKELPIYTSTLLLANNELDKIKADGLFEKLPELQHLDLRKNKISRIEASSFQGAH
KLTDLLLSENRLREVHNKMFTGLTNLKTLNLHGNAITCVMQGSFDGLTHIRTINMQGNPLSCNCHLAWFAGWLRKRETPL
SGVVGHCHDPPRLKDAIVKDIPHHEFKCNNDSVGCLGDDYCPPQCNCAGSVVRCSRSQLTEIPRGIPPETTELYLDVNDI
KTIQPERLNHLRILTRLDLSNNQIGMLSNDTFRNLTKLSHLIISYNKLQCVQRNALAGLKSLRIMSLHGNDISVIPEGAF
EDLQSITHLALGSNPLYCDCSMRWLAEWVKKDYVEAGIARCMEPPAMRDKLLLTTPATAFQCKTEVLAKCDLCYTSPCQN
GGFCEALPDRKFRCKCAPGYHG-DRCEHKIDACYGNPCGNTGTCKVLEEGRFSCDCAPGYKGLRCENNVDDCEDNKCSNN
STCVDLVQAYRCECAPGFMGEYCEEKIPFCTKGHDPC----------ENGGRCVDHGTHYSCECPIGFTGLNCSTNLDDC
VDHMCQNGATCIDGINNY---ECKCAAD--YTGRYCEAAPSTVML-----------------------------------
YPQTSPCAHHDCQHGACFQPAPASAADYLCQCHPGYTGKRCEYLTSLSFVDNSSLVELEPLRTRPEANVTIVFTTTQENG
VLLYNGQNGDHIAVELFNGRVRVSYDVGNYPTSTMYSYEMVADGKAHVAELLAIKKNFTMRVDNGAARSIINEGPKEYLK
LVAPMYVGGVAPEVANVAFTEFHLRNITSFQGCISEMWINHKLVDFSNAAKMHRVTPGCMSNEEEADEARDVVEAEGIVM
TGPGTIISDPCTGHECRKGSQCVPSPIGNGYTCRCQTGWQGRYCEKAPTCRKEHTREYYSENGCRSRRPVKLAKCWGSCG
NSCCLPRKTKRRKVRLICADGMRYTKDVDLVRKCTCTRKCY---------------------------------------
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>Ciona_intestinalis-WISP1(ENSCINP_13895)
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-------------------------------MLFSVYIVMMIVTSQFYLSMATPNFDLRRSNQSTEGDFYPARSEARECQ
DCTCPDTPG-----TCPPGVS------------------------RIMDG---CDC---------------CKMCAKQLN
EPCDVR---MRCDHHKGLYC------DMNTGLCKAS------------PGVACYVGGSWYDNGQTF--------------
-QLSCKVTCSCIDGD-------IACMP-------TCLPHKPS--------------------------------------
-IRECRHPRLIHRRGEC-------CEEWVCT------RNGRLDPGIELQ-------------------------------
----------------------EHEVKERPVQPVVFRENCMVQTTEWSDCSKSCGFGVSNRVSNDNADCKLKKEMR----
--------------------------LCNIRPCSMTESTVITR-------------------RRSCRKTIRHSSRVRFSL
SG------------------------------CLSRDTYRQKYCGFCT--------------------------------
GKCCGPKVSKTIKVQFNCESGTNFTRNMMMIKKCSCS-SCPNDFLNLSTYNRAMVGDMVRST------------------
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>Ciona_savignyi-WISP1(ENSCSAVP_13965)
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---------------------------------------------------------CPY--------------------
ECACQNEPK-----HCPIGVS------------------------LVTDG---CNC---------------CKVCARQVG
DECNDQE--KVCDPHRNLFCDYSGSRSGDLGVCRAR------------SGRPCMNNGVRLSSGAEY--------------
-EPSCKYRCWCIDGN-------EGCLP-------LCPHETQVPK------------------------------------
-FSVCPNARLVPVSGEC-------CDQWECDSPTGEVVRIDCLSAYASE-------------------------------
----------------------DTVIVVEHHERTRGHSSCVVHTSAWSPCSKTCGLGVSVRVSNDNPQCQLSRGMR----
--------------------------LCQLRPCQGNR-YSPKK-------------------GRHCLRQKRAPKRETLTY
AG------------------------------CTSQRKSRPRYCGGCNNP------------------------------
SRCCTPKLTRTISVRFRCPNGSIFSKNVMVIRSCQCHSNCSRSAIHREVFQYALHDDML---------------------
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>Branchiostoma_floridae-WISP1(C_110154)
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-------------------------------------------------MKVTQSSVAAVVVFLTCLVHALPEGKGGCDG
TCACPAQPV-----TCVPGVR------------------------LLEDR---CGCR--------------CKVCASLLG
EECSEM---APCDDTVGLYCDYSADKPTGICKATF--------------QTPCVFQGKVYQSGESF--------------
-ELSCRETCVCQNGA-------VGCMP-------LCPQEVRMP-------------------------------------
-SDDCPFPQLEKVPGKC-------CKQWMCDAKPKELSAKGPMPMIAG--------------------------------
------------------------KLERKPETEYPEPVACLLQATSWSQCSVTCGMGVSTRVSNHNPECRMQVEKR----
--------------------------ICQMRPCDLQYLNHIKVRTSL------FIKSRGGWDGKKCRSTIRSMEPSKITF
SWY--------------------------NTRCTTVKAYKWRWCGGCTIS------------------------------
GRCCTPYKVKTTTMDFICEDRTPIKQDVAWIHSCTCHRNCPLA-------------------------------------
------------------------------------
>Homo_sapiens-WISP2(ENSP_190983)
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------MRGTPKTHLLAFSLLCLLSKVRTQLCPT
PCTCPWPPP-----RCPLGVP------------------------LVLDG---CGC---------------CRVCARRLG
EPCDQL---HVCDASQGLVCQPGAGPGGRGALCLLAE-----------DDSSCEVNGRLYREGETF--------------
-QPHCSIRCRCEDGG-------FTCVP-------LCSEDVRLP-------------------------------------
-SWDCPHPRRVEVLGKC-------CPEWVCGQGGG-LGTQPLPAQG----------------------------------
--------------------PQFSGLVS----SLPPGVPCPEWSTAWGPCSTTCGLGMATRVSNQNRFCRLETQRR----
--------------------------LCLSRPCPPSRGRS----------------------PQNSAF------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Macaca_mulatta-WISP2(ENSMMUP_13901)
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------VAE-----------DDGSCEVNGRLYQEGETF--------------
-QPHCSIRCRCEDGG-------FTCVP-------LCSEDVRLP-------------------------------------
-SWDCPYPRRVEVLGKC-------CPEWVCGQGGG-LGAQPLPAQG----------------------------------
--------------------PQFSGLVS----SLPPGVPCPEWSTAWGPCSTTCGLGMATRVTNQNRFCRLETQRR----
--------------------------LCLSRPCPPSRGRS----------------------PRNSAF------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Mus_musculus-WISP2(ENSMUSP_29188)
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------MRGNPLIHLLAISFLCILSMVYAQLCPA
PCACPWTPP-----QCPPGVP------------------------LVLDG---CGC---------------CRVCARRLG
ESCDHL---HVCDPSQGLVCQPGAGPSGRGAVCLFEE-----------DDGSCEVNGRRYLDGETF--------------
-KPNCRVLCRCDDGG-------FTCLP-------LCSEDVRLP-------------------------------------
-SWDCPRPRRIQVPGRC-------CPEWVCDQAVMQPAIQPSSAQG----------------------------------
--------------------HQLSALVT----PASADGPCPNWSTAWGPCSTTCGLGIATRVSNQNRFCQLEIQRR----
--------------------------LCLSRPCLASRSHG----------------------SWNSAF------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Rattus_norvegicus-WISP2(ENSRNOP_14346)
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------MRGSPLIHLLATSFLCLLSMVCAQLCRT
PCTCPWTPP-----QCPQGVP------------------------LVLDG---CGC---------------CKVCARRLG
ESCDHL---HVCDPSQGLVCQPGAGPGGHGAVCLLDE-----------DDGSCEVNGRRYLDGETF--------------
-KPNCRVLCRCDDGG-------FTCLP-------LCSEDVRLP-------------------------------------
-SWDCPRPKRIQVPGRC-------CPEWVCDQGVT-PAIQRSTAQG----------------------------------
--------------------HQLSALVT----PASADAPCPNWSTAWGPCSTTCGLGIATRVSNQNRFCQLEIQRR----
--------------------------LCLPRPCLAARSHS----------------------SWNSAF------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Canis_familiaris-WISP2(ENSCAFP_13996)
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------MRGTPQTLLLAFSLLCLLSKVCAQLCPT
PCACPWPPP-----RCPPGVP------------------------LVLDG---CSC---------------CRVCARRLG
EPCDHL---HVCDPSQGLVCQPRAGPGGRGALCLWGD-----------DEGSCEVNGRVYQDGETF--------------
-QPHCRIRCHCEDGG-------FTCVP-------LCSEDVRLP-------------------------------------
-SWDCPHPRRVEVPGRC-------CPEWVCDRGGE-LGTQPLPAQGG---------------------------------
--------------------PQFSGLAA----PPPPGVPCPEWSTAWGPCSTTCGLGVATRVSNQNLLCRLETQRR----
--------------------------LCLPRPCPPARGRS----------------------PWNSTF------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Loxodonta_africana-WISP2(ENSLAFP_2517)
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------MRGRSQTHLLTFFLLFLLSKVCAQLCPT
PCACPWPPP-----RCPLGVP------------------------LVLDG---CGC---------------CRVCARRLG
EPCDHL---HVCDSSQGLVCQLG-RPCARGALCLLGE-----------DDGTCEVNGRLYQDGETF--------------
-QPHCRIRCRCEDGG-------FTCVS-------LCSEDVLLP-------------------------------------
-SRDCPQPRRVEVPGKC-------CPEWVCTDT---LGVQTLPARE----------------------------------
--------------------PQFFGLVA----PQP--MPCPEWSTAWSACSTTCGLGVATRVSNQNRFCRLETQRR----
--------------------------LCFPGLCPPARGRS----------------------PPYRAF------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Equus_caballus-WISP2(ENSECAP_12197)
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------MRGTLQTHLLAFSLLCLFSKVCAQLCPT
PCACPWPPP-----RCPLGVP------------------------LVLDG---CNC---------------CQVCARRLG
EPCDHR---HVCDSSQGLVCQP--VPGGRGAVCLWGE-----------DDGRCEVNGRVYRDGETF--------------
-QPHCRLRCRCEDGG-------FTCVP-------LCPEDVRLP-------------------------------------
-SRDCPRPRRVDVPGRC-------CPEWVCDQGAG-PGVQPLPAQG----------------------------------
--------------------PQFSGFVA----PSSPGVPCPEWSTAWGPCSTTCGLGITTRVSNQNPFCRLETQRR----
--------------------------LCLPGPCPPPRGRS----------------------PWNSTF------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Myotis_lucifugus-WISP2(ENSMLUP_14745)
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------MRGTPQTHLLAVSFLCLLSKVCAQLCPM
PCACPWPPP-----QCPPGVP------------------------LVLDG---CNC---------------CRVCARRLG
EPCDHL---HVCDSSQGLVCQLGAGPGGQGAVCLWAE-----------DDGSCEVNGRRFRDGEAF--------------
-QPHCRVRCRCEDGG-------FTCVP-------LCSEDVRLP-------------------------------------
-SWDCPHPRRVEVPGKC-------CPEWVCDQAGA-LGGQPLLAPG----------------------------------
--------------------LQAAGLVA----PLPPGVPCPEWSTAWGPCSTTCGLGVTTRVSNQNRFCRLETQRR----
--------------------------LCLPGPCPPARGHN----------------------PLLGAF------------
--------------------------------------------------------------------------------
-------------------------------------------------------