>Homo_sapiens_RNF13
--------------------------------------------------------------------------------
--------------------MLLSIGMLMLSATQVYTILT-VQLFAFLN-------------------------------
LLPVEADILAYNFENASQT----------------FDDLPARFGYRLPAEGLKGFLINSK-------PENACEPIVPPP-
VK--------DNSSGTFIVLIRRLD--CNFDIKVLNAQRAGYKAAIVHNV----DSDDLISMGSNDIEV--LKKIDIPSV
FIGESSANSLKDEFTYEKGGHLILVPEFSL-----------------------------PLEYYLIPFLIIVGICLILIV
IFMITK----FVQDRHRARRNRLRKD--QLKKLPVHK-FKKG-----------------------------DEYDVCAIC
LDEYEDGDKLRILPC-SHAYHCKCVDPWLTKTKK---TCPVCKQKVVPSQ------------------------------
---------GDSDS---DTDSSQEENE-VTEHTPL---------------LRPLASVSAQ--------------------
--------------------------------------------------------------------------------
--------------------------------------------SFGALSESRSHQNMTESSDYEE--------------
---------DDNEDTDSSDAENEINEHDVVVQLQPNGERDYNIANTV---------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Pan_troglodytes_RNF13
--------------------------------------------------------------------------------
--------------------MLLSIGMLMLSATQVYTILT-VQLFAFLN-------------------------------
LLPVEADILAYNFENASQT----------------FDDLPARFGYRLPAEGLKGFLINSK-------PENACEPIVPPP-
VK--------DNSSGTFIVLIRRLD--CNFDIKVLNAQRAGYKAAIVHNV----DSDDLISMGSNDIEV--LKKIDIPSV
FIGESSANSLKDEFTYEKGGHLILVPEFSL-----------------------------PLEYYLIPFLIIVGICLILIV
IFMITK----FVQDRHRARRNRLRKD--QLKKLPVHK-FKKG-----------------------------DEYDVCAIC
LDEYEDGDKLRILPC-SHAYHCKCVDPWLTKTKK---TCPVCKQKVVPSQ------------------------------
---------GDSDS---DTDSSQEENE-VTEHTPL---------------LRPLASVSAQ--------------------
--------------------------------------------------------------------------------
--------------------------------------------SFGALSESRSHQNMTESSDYEE--------------
---------DDNEDTDSSDAENEINEHDVVVQLQPNGERDYNIANTV---------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Gorilla_gorilla_RNF13
--------------------------------------------------------------------------------
--------------------MLLSIGMLMLSATQVYTILT-VQLFAFLN-------------------------------
LLPVEADILAYNFENASQT----------------FDDLPARFGYRLPAEGLKGFLINSK-------PENACEPIVPPP-
VK--------DNSSGTFIVLIRRLD--CNFDIKVLNAQRAGYKAAIVHNV----DSDDLISMGSNDIEV--LKKIDIPSV
FIGESSANSLKDEFTYEKGGHLILVPEFSL-----------------------------PLEYYLIPFLIIVGICLILIV
IFMITK----FVQDRHRARRNRLRKD--QLKKLPVHK-FKKG-----------------------------DEYDVCAIC
LDEYEDGDKLRILPC-SHAYHCKCVDPWLTKTKK---TCPVCKQKVVPSQ------------------------------
---------GDSDS---DTDSSQEENE-VTEHTPL---------------LRPLASVSAQ--------------------
--------------------------------------------------------------------------------
--------------------------------------------SFGALSESRSHQNMTESSDYEE--------------
---------DDNEDTDSSDAENEINEHDVVVQLQPNGERDYNIANTV---------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Macaca_mulatta_RNF13
--------------------------------------------------------------------------------
--------------------MLLSIGMLMLSATQVYTILT-VQLFAFLN-------------------------------
LLPVEADILAYNFENASQT----------------FDDLPARFGYRLPAEGLKGFLINSK-------PENACEPIVPPP-
VK--------DNSSGAFIVLIRRLD--CNFDIKVC-VYTSISSLSFISSM----TLDKIILLFFYTVEV--LKKIDIPSV
FIGESSANSLKDEFTYEKGGHLILVPEFSL-----------------------------PLEYYLIPFLIIVGICLILIV
IFMITK----FVQDRHRARRNRLRKD--QLKKLPVHK-FKKG-----------------------------DEYDVCAIC
LDEYEDGDKLRILPC-SHAYHCKCVDPWLTKTKK---TCPVCKQKVVPSQ------------------------------
---------GDSDS---DTDSSQEENE-VTEHTPL---------------LRPLASVSAQ--------------------
--------------------------------------------------------------------------------
--------------------------------------------SFGALSESRSHQNMTESSDYEE--------------
---------DDNEDTDSSDAENEINEHDVVVQLQPNGERDYNIANTV---------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Bos_taurus_RNF13
--------------------------------------------------------------------------------
--------------------MLLSIGMLMLSATQVYTILT-VQLFAFLN-------------------------------
LLPVEADILAYNFENASQT----------------FDDLPARFGYRLPAEGLKGFLINSK-------PENACEPIVPPP-
VR--------DNSSGTFIVLIRRLD--CNFDEKVLNAQRAGYKAAIVHNV----DSDDLISMGSNDIEV--LKKIDIPSV
FIGESSANSLKDEFTYEKGGHIILVPEFSL-----------------------------PLEYYLIPFLIIVGICLILIV
IFMITK----FVQDRHRARRNRLRKD--QLKKLPVHK-FKKG-----------------------------DEYDVCAIC
LDEYEDGDKLRILPC-SHAYHCKCVDPWLTKTKK---TCPVCKQKVVPSQ------------------------------
---------GDSDS---DTDSSQEENE-VSEHTPL---------------LRPLASASTQ--------------------
--------------------------------------------------------------------------------
--------------------------------------------SFGALSESRSHQNMTESSDYEE--------------
---------DDN-DTDSSDAENEINEHSVVVQLQPNGERDYNIANTV---------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Loxodonta_africana_RNF13
--------------------------------------------------------------------------------
--------------------MLLSIGMLMLSATQVYTILT-VQLFAFLN-------------------------------
LLPVEADILAVSTENASQT----------------FDDLPARFGYRLPAEGLKGFLINSK-------PENACEPIVPPP-
LK--------DNSSGTFIVLIRRLD--CNFDVKVLNAQRAGFKAAIVHNV----DSDDLISMGSNDIEV--LKKIDIPSV
FIGESSANSLKDEFTYEKGGHIVLVPEFSL-----------------------------PLEYYLIPFLIIVGICLILIV
IFMITK----FVQDRHRARRNRLRKD--QLKKLPIHK-FKKG-----------------------------DEYDVCAIC
LDEYEDGDKLRILPC-SHAYHCKCVDPWLTKTKK---TCPVCKQKVVPSQ------------------------------
---------GDSDS---DTDSSQEENE-VSEHTPL---------------LRPLASVSAQ--------------------
--------------------------------------------------------------------------------
--------------------------------------------SFGALAESRSRQNTTESSDYEE--------------
---------DDHEDTDSSDAENDISEHSVVVQLQPDGGRDYNIANTV---------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Takifugu_rubripes_RNF13_a
--------------------------------------------------------------------------------
--------------------MLLSLGMLMLSATQIYTIFT-VQLFAFLN-------------------------------
LLPVEADIAAYTFDNKTES----------------FEDLPARFGYRLPTEGLKGFLIGAR-------PENACEPIEPPP-
-R--------DNLTGAFIVLIKRFE--CNFDVKVLNAQKAGYRAAIVHNV----NSDDLISMGSNDLDI--MKQIDIPSV
FVSEETANSLKEDYIYDKGGHVVLMPDFSL-----------------------------PLEYYLIPFLIIVGICLILIV
VFMITK----FVQDRRRARRSRLHKD--QLKKLPIHK-YKK--G---------------------------DSYDVCAIC
LDEYEEGDKLRVLPC-SHAYHSKCVDPWLTKTKK---TCPVCKQKVVPSQ------------------------------
---------GDSDSDSEEGDSGPDENE-VSESTPL---------------LRSLASTSAH--------------------
--------------------------------------------------------------------------------
--------------------------------------------SFGTMSAESRSEQDQDSSEY-D--------------
------------EELDSSDSEE-VTVETVVVQMQQPRSDGRDHDPARV--------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Tetraodon_nigroviridis_RNF13_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------RR-------P-----CLVPP--
--------------------------------QVLNAQKAGYRAAIVHNV----NSDDLISMGSNDVDV--MKQIDIPSV
FVSEETANSLKGGYLYDKGGHLVLMPDFSL-----------------------------PLEYYLIPFLIIVGICLILIV
VFMITK----FVQDRRRARRSRLHKD--QLKKLPIHK-YKK--G---------------------------DSYDVCAIC
LDEYEDGDKLRVLPC-SHAYHSKCVDPWLTKTKK---TCPVCKQKVVPSQ------------------------------
---------GDSDSDSEEGDSGPDENE-ASESTPL---------------LRSLASTSAH--------------------
--------------------------------------------------------------------------------
--------------------------------------------SFGTMSAGSRSEHDQESSEY-D--------------
------------EELDS------MTVETVVVQMQPPQ-----QDPTRV--------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Gasterosteus_aculeatus_RNF13_a
--------------------------------------------------------------------------------
--------------------MLLSLGMLMLSATQIYTIFT-VQLFAFLN-------------------------------
LLPVGADIAAYSFDNKTEN----------------FDDLPARFGYRLPSDGLKGFLIGAR-------PENACEPIEPPP-
-R--------DNMTGAYIVLIKRFD--CNFDIKVLHAQKAGYKAAIVHNV----VSDDLISMGSNDLDI--MKQIDIPSV
FVSEQTANSLKEDFAFDKGGHVVLMPDFSL-----------------------------PLEYYLIPFLIIVGICLILIV
VFMITK----FVQDRHRARRSRLRKD--QLKKLPIHK-YKKDTG---------------------------DNYDVCAIC
LDEYEEGDKLRVLPC-SHAYHSKCVDPWLTKTKK---TCPVCKQKVVPSQ------------------------------
---------GDSDS--EEGGSGPDENEEVSESTPL---------------LRSLASTSAH--------------------
--------------------------------------------------------------------------------
--------------------------------------------SFGTMSGASRSEHEQESSDYED--------------
------------DELDSSEEEEEVTVETVVVQMQQPCPEGLEHDL-----------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Strongylocentrotus_purpuratus_RNF13
--------------------------------------------------------------------------------
---------------------MMLFSSRRSYQMKMDVGQVVVALVVLCT-------------------------------
EIMQITADVIATSQHNDTTA---------------FQSVTAAFGSP-PDGQMQGLLVVAN-------PIEACGPIQ----
-VPPLL---PNVTGVY-FALIKRGS--CNFDKKVYNAQQARYMGAIVYND----EGNVLTTMSGSQ----YNKLIYIPSV
FVGKDSGETLQGMNYSTGYHVVLLATESPS------------------------------LGFYFLPFISVTSTCLLFFA
MYAIAK----YVRDQRRQRKARLSRD--HLKKLPIKX-XSSGDE-----------------------------YDICAIC
LDDYEEGQKLRILPC-NHAYHCKCIDPWLTNNRR---TCPICKRKVIPPG------------------------------
---------MADSDEE-SDSEAGDAPNENTPLLSS---------------MHSDNLSDHG--------------------
--------------------------------------------------------------------------------
--------------------------------------------AVGGLAETATPPPSPMTSVEGDDY------------
--------PPIDTLIKVESDSESSGSFPLEEAKGNIQDPPNSNVLSVTVHSENEIDPSTSSAPKV---------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Apis_mellifera_RNF13
--------------------------------------------------------------------------------
---------------MKQCCLS------------HQLQLWLMFLVFCVM-------------------------------
CNRADILVFSAAARHQIEEE---------------FRDMPARFGGLIPSEGIKGMVVYAE-------PPTACHEIQGPPN
STSY---------IGNWISLIARYN--CSFERKVRMAQKAGYDAVIIHNV----NSNKLEPMLAKDPTG-----IIIPSV
FVSEITGLIIKENYLYDELYFVLINDDSPF----------------------------NIT-HLLLPFAIVVGICFLIMV
IFMIVR----CIKDRRRQQRHRLPNS--SLKKIPTHK-YTKG-----------------------------DPYETCAIC
LDDYAEGEKLRVLPC-AHAYHTKCIDPWLTKNRR---VCPVCKRKVFA--------------------------------
----------ADEQV---VTDE--SDSDADDTTPL---------------IREGHQGTQG----------GTFSR-----
--------------------------------------------------------------------------------
---------------------QRENPFNRARRSQTRQH------DIIHFNSSSDSEELLDTT------------------
------------DEEASVSAGE----PSSGTVFRPFDIHSING--------ELPDLECSVSSTKPH--TVNLYT------
---------------------------------DVEEFPAP-------VVQITNCNIRTN---------SQTSNSGGSVP
IESEATNFINTDSEK---IDIHV---------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Anopheles_gambiae_RNF13
------------------------------------------------------------------------------ML
PQSLIMVKGGYARRPMNRAAHRSPKFVHHRQYHHRLVMLVAMVLMLAQP-------------------------------
CVRADILVYQMLN-DQIIEE---------------FRDLPATFGGEIPDSGLKVLADRAD-------PPDGCTEMRPAPN
ITS------------KFAVVIARYN--CSFEVKVRNAQQAGYAMVIVHNV----GSNDLEHMSANHPQD-----LLIPSV
FVGESAGRSIIEAYLYDHDYALVITDDIPF----------------------------NISNNLIIPFAIVVGLCFIIMV
LFMIIR----CIRERRRRMRHRLPAR--VLRKIGIVK-FAKG-----------------------------MRFDTCAIC
LEDFVENERLRVLPC-RHAYHAICIDPWLTKNRR---VCPICKRRVIVRG------------------------------
---------EARQRR---YSSDSMSSTNADESTPL---------------LNSTENSTSGSAAGVVTAPPATSSSSPVTA
AVAPSGNSGAG---------------------------------------------------------------------
--------------------AQTAAAAAPQRDQQQLQQNAAPDSHVMEVPPSDDDDEMLDDRNVPSARWLLRGRTSSQQQ
HQQQQQPQQQPLNESPYSPIGDNVATPSRWRFFQRFFTRSTAQSDTEGNNIQEPPAPAQAPSPQPFSPTVPLGTGNNILN
AHLSGSFHGSEDTTDDELLDAMQRDRTKQRQFRSAPDMPSTSVGARLGVAALPNVNFNPAGGGANAPAAPAESSSGGGAP
RRYPRQPMPRHERRRNGNNNSHIV--------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Nematostella_vectensis_RNF13
--------------------------------------------------------------------------------
----------------------MERTFLLAVLLTIFVSSGLGEDTTTLT-------------------------------
DYNRICVIPLGQSVNETEKC---------------YEYGLADFG-QLLSRSIQGFGVLAS-------PKNACSTV----Q
PIKSK------SNMFWFLVIE-DGG--CSFGEKAYMAQKGEYDAAIIYSL----TSDKIIDMESDEYG--RK-ADDIVAI
HIGKTAAKELTRIDVLARNN---IVINPQYL-------------------------LLWNLEVYILPFAVIVGICFVLMG
LFMISR----YYRHYLEKRRNRLSLT--NLRKIPTKK-FKKGDEYYDVCAICLDEYKEGDKLRILPCDHGDEYYDVCAIC
LDEYKEGDKLRILPC-DHAYHCKCVDPWLTEGKR---TCPVCKRPVETSK------------------------------
---------KKK-------QGIQGSADAEQG---H---------------HEHEPSETTP--------------------
--------------------------------------------------------------------------------
--------------------------------------------LIRPSTQTSTALPV----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Hydra_magnipapillata_RNF13
--------------------------------------------------------------------------------
-------------------------TYEMINWYYLLVICLQMVNLVSLT-------------------------------
IYT----YPPAHS-NLSKLM---------------FHDVEADFG-SMPTEGISGALDLSI-------PYNACYHL----Y
PAPKKD---LPNTNFFALIQE-SSG--CSYSEQVIHAQEAGYKGAIIYSR----TNNDPIIMGGD--------GPIIVAV
YVKKSVGQDLKQFLYKTGST---IKIAPNDP-------------------------QMS-LSIYLVPFAIVVGVCFFFML
AFSVGR----YVRYWLRIRRSRLSPA--NLKKIPTKK-FKKGDE-----------------------------FDVCAIC
IEEYVQNDKIRILPC-NHAYHCKCVDPWLTSGKK---LCPVCKQTVESDL------------------------------
---------KRTSKNV-IINGNDGNSNDVNGSSAL---------------TEESEDENTP--------------------
--------------------------------------------------------------------------------
--------------------------------------------LLAASQNLPNSGAMA---------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Branchiostoma_floridae_RNF13
--------------------------------------------------------------------------------
---------------------MFPCRPVPSYITVLYIYAVINLFLLLH--------------------------------
-VCTVDADVIVTDSINNTVN---------------FMDMPSNFGSQLPDMGIQGYLAAVN-------PPHACKAVG----
-PPP-----PNITELNPIALIRRGN--CDFDIKVLNAEKSGFKAAIVYND----ESDVILQMNGNKCKFVYYMEVTIPSV
FVGLTDGMELQRYDWRTGSQVKLTPDFTIP------------------------------LHFYLLPFAIIVGICFVLML
IFMVAK----FVRDRRRQRRSRLSKE--HLKKIPTKK-FKKGDE-----------------------------YDVCAIC
LDDYEEGDKLRILPC-SHG---------RSYNRS---I------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Homo_sapiens_RNF43
--------------------------------------------------------------------------------
-----------------------MSGGHQLQLAALWPWLLMATLQAGFGR-----------------------------T
GLVLAAAVESERSAEQKAIIR-----------VIPLKMDPTGKLNLTLEGVFAGVAEITP--AEGKLMQS--HPLYLCNA
SDDDNLEPG-FISIVKLESPRRAPRP-CLSLASKARMAGERGASAVLFDITEDRAAAEQLQQP--LGLTWPVVLIWGNDA
EKLMEFVYKNQKAHVRIELK----EPP-AWPD------------------------YDVWILMTVVGTIFVIILASVLRI
RCRPRHSRPDPLQQRTAWAISQLATRRYQAS-CRQARGEWPDSGSSCSS------------------------APVCAIC
LEEFSEGQELRVISC-LHEFHRNCVDPWLHQHRT----CPLCMFNITEGD-------------SFSQSLGPSRSYQ----
-------------EPGRRLHLIRQHPGHAHYHLPAAYLLGPSRS-AVARPPRPGPFLPSQ---EPGM----GPRHHRFPR
AAHP--------------RAPGEQQRLAGAQ--HPYAQGWGLSHLQ-STSQH-----------------PA-ACPVP---
-----------------------------LRRARPPDSSGSGESYC---TERSGYLADGPASDSSS------------GP
CHGSSSDSVVNCTDISLQGVHGSSSTFCSSLSSDFDPLVYCSPK------------------------------------
-------GDPQRVDMQPSVTS---RPRSLDSVVP-------TGETQVSSHVHYHRHRHHHYKKRF-----QWHGRKPGPE
TGVPQSRPPIPRTQPQPEPPSPDQQVTRSNSAAPSGRLSNPQCPRALPEPAPGPVDASSICP----STSSLFNLQKSSLS
ARHPQRKRRGGPSEPTPGSRPQDATVHPACQIFPHYTPSVAYPWSPEAHPLICGPPGLDKRLLPETPGPCYSNSQPVWLC
LTPRQPLEPHPPGEGPSEWSSDTAEGRPCPYPHCQVLSAQPGSEEE-LEELCEQAV------------------------
-
>Mus_musculus_RNF43
--------------------------------------------------------------------------------
-----------------------MSGGHQLQLAVLWPWLLMATLHAGFGH-----------------------------T
GRVLAAAVESERSAEQKAVIR-----------VIPLKMDPTGKLNLTLEGVFAGVAEVTP--AEGKLMQS--HPLYLCNA
SDDDNLEPG-FISIVKLESPRRAPRP-CLSLASKARMAGERGANAVLFDITEDRSAAEQLQQP--LGLTKPVVLIWGSDA
AKLMEFVYKNRKAYVWIELK----EPP-AGAN------------------------YDVWILLTVVGTVFVIILASVLRI
RCRPHHSRPDPLQQRTARAISQLATRRYQAG-CRRARAEWPDSGSSCSS------------------------TPVCAIC
LEEFSEGQELRVISC-LHEFHRTCVDPWLYQHRT----CPLCMFNIVEGD-------------SFSQAPAASPSYQ----
-------------EPGRRLHLIRQHPGHAHYHLPSAYLLGPSRT-SVARTPRPRPFLPSQ---EPSM----GSRHQRLPR
TSHL--------------RAPEEQQHLAVSP--HPYAQGWGLNRLR-CTSQH-----------------PA-ACPVA---
-----------------------------LRRARPHESSGSGESYC---TERSGYLADGPASDSSS------------GP
CHGSSSDSVVNCTDVSLQGIHGSSSTFRSSLSSDFDPLVYCSPE------------------------------------
-------GDLQGKGIQPSVTS---RPRSLDSVVP-------RGETQVSSHIHYHRHRHHHYKRQF-----QWHGRKPGPE
TGIPQSMPAASHT--QLEPSLPDQQLITPNPTASS-MLPNPQRPRALTEPAPGLAEASSPSPSPKPNPSGLLNLQKSSLT
VRHPHRKRRGGPSEPLPTSLPPDLTVHTACPVFPHYSPRLAYPWPPEVHPLMFRPPGPDRRLLHEVPGPCYSSSQPVWLY
LNPCQPLGPCLPGEGHSKWTFDSPEGRRCPYSHCQVLPAQPGSEEE-LEELCEQAV------------------------
-
>Pan_troglodytes_RNF43
--------------------------------------------------------------------------------
-----------------------MSGGHQLQLAALWPWLLMATLQAGFGR-----------------------------T
GLVLAAAVESERSAEQKAIIR-----------VIPLKMDPTGKLNLTLEGVFAGVAEITP--AEGKLMQS--HPLYLCNA
SDDDHLEPG-FISIVKLESPRRAPRP-CLSLASKARMAGERGASAVLFDITEDRAAAEQLQQP--LGLTWPVVLIWGNDA
EKLMEFVYKNQKAHVRIELK----EPP-AWPD------------------------YDVWILLTVVGTIFVIILASVLRI
RCRPRHSRPDPLQQRTAWAISQLATRRYQAS-CRQARGEWPDSGSSCSS------------------------APVCAIC
LEEFSEGQELRVISC-LHEFHRNCVDPWLHQHRT----CPLCMFNIIEGD-------------SFSQSLGPSRSYQ----
-------------EPGRRLHLIRQHPGHAHYHLPAAYLLGPSRS-AVARPPRPGPFLASQ---EPGM----GPRHHRFPR
AAHP--------------RAPGEQQRLAGAQ--HPYAQGWGLSHLQ-STSQH-----------------PA-ACPVP---
-----------------------------LRRARPPDSSGSGESYC---TERSGYLADGPASDSSS------------GP
CHGSSSDSVVNCTDISLQGVHGSSSTFCSSLSSDFDPLVYCSPK------------------------------------
-------GDPQRVDMQPSVTS---RPRSLDSVVP-------TGETQVSSHVHYHRHRHHHYKKRF-----QWHGRKPGPE
TGVPQSRPPIPRTQPQPEPPSPDQQVTRSNSAAPSGRLSNPQCPRALPEPAPGPVEASSICP----STSSLFNLQKSSLS
ARHPQRKRRGGPSEPTPGSRPQDATVHPACQIFPHYTPSVAYPWSPEAHPLICGPPGLDRRLLPETPGPCYSNSQPVWLC
LTPRQPPEPHPPGEGPSEWSSDTAEGRPCPYPHCQVLSAQPGSEEE-LEELCEQAV------------------------
-
>Gorilla_gorilla_RNF43
--------------------------------------------------------------------------------
-----------------------MSGGHQLQLAALWPWLLMATLQAGFGR-----------------------------T
GLVLAAAVESERSAEQKAIIR-----------VIPLKMDPTGKLNLTLEGVFAGVAEITP--AEGKLMQS--HPLYLCNA
SDDDNLEPG-FISIVKLESPRRAPRP-CLSLASKARMAGERGASAVLFDITEDRAAAEQLQQP--LGLTWPVVLIWGNDA
EKLMEFVYKNQKAHVRIELK----EPP-AWPD------------------------YDVWILLTVVGTIFVIILASVLRI
RCRPHHSRPDPLQQRTAWAISQLATRRYQAS-CRQARGEWPDSGSSCSS------------------------APVCAIC
LEEFSEGQELRVISC-LHEFHRNCVDPWLHQHRT----CPLCMFNIIEGD-------------SFSQSLGPSRSYQ----
-------------EPGRRLHLIRQHPGHAHYHLPAAYLLGPSRS-AVARPPRPGPFLPSQ---EPGM----GPRHHRFPR
AAHP--------------RAPGEQQRLAGAQ--HPYAQGWGLSHLQ-STSQH-----------------PA-ACPVP---
-----------------------------LRRARPPDSSGSGESYC---TERSGYLADGPASDSSS------------GP
CHGSSSDSVVNCTDISLQGVHGSSSTFCSSLSSDFDPLVYCSPK------------------------------------
-------GDPQRVDMQPSVTS---RPRSLDSVVP-------TGETQVSSHVHYHRHRHHHYKKRF-----QWHGRKPGPE
TGVPQSRPPIPRTQPQPEPPSPDQQVTRSNSAAPSGRLSNPQCPRALPEPAPGPVEASSICP----STSSLFSLQKSSLS
ARHPQRKRRGGPSEPTPGSRPQDATVHPACQIFPHYTPSVAYPWSPEAHPLICGPPGLDRRLLPETPGPCYSNSQPVWLC
LTPRQPPEPHPPGEGPSEWSSDTTEGRPCPYPHCQVLSAQPGSEEE-LEELCEQAV------------------------
-
>Macaca_mulatta_RNF43
--------------------------------------------------------------------------------
-----------------------MSGGHQLQLAALWPWLLMATLQAGFGR-----------------------------T
GLVLAAAVESERSAEQKAIIR-----------VIPLKMDPTGKLNLTLEGVFAGVAEITP--AEGKLMQAKSHPLYLCNA
SDDDNLEPG-FISIVKLESPRRAPRP-CLSLASKARMAGERGASAVLFDITEDRAAAEQLQQP--LGLTWPVVLIWGNDA
EKLMEFVYKNQKAHVRIELK----EPP-AWPD------------------------YDVWILLTVVGTIFVIILASVLRI
RCRPRHSRPDPLQQRTAWAISQLATRRYQAS-CRQAQGEWPDSGSSCSS------------------------APVCAIC
LEEFSEGQELRVISC-LHEFHRNCVDPWLHQHRT----CPLCMFNIIEGD-------------SFSQSLGPSRSYQ----
-------------EPGRRLHLIRQHPGHAHYHLPAAYLLGPSQS-TVAWPPQPGPFLPSQ---EPGM----GPRHHRLPR
AAHP--------------RAPGEQQRLAGAQ--HPYAQGWGLSHLQ-STSQH-----------------PA-ARPVP---
-----------------------------LRRARPPDSSGSGESYC---TERSGYLADGPASDSSS------------GP
CHGSSSDSVVNCTDISLQGVHGSSSTFCSSLSSDFDSLVYCSPE------------------------------------
-------GDPQRVDMHPSVTS---RPRSLDSVVP-------TGETQVSSHVHYHRHRHHHYKKRF-----QWHGRKPGPE
TGVPSSRPPIPRTQPQPEPASPDQHVTRSNSAVPSGRLSNPQRPRALPEPAPGPVEASSICL----STSSLFNLQKSSLS
ARHPQRKRRGCPSEPTPGSRPQDATVHPACQIFPHFTPSVAYSWSPEAHPLIFGPPGLDRRLLPETPGPCYSNSQPVWLC
LTPHRSPEPHPPGEGPSEWSSDTAEGRPCPHPHCQVLSAQPGSEEE-LEELCEQAV------------------------
-
>Bos_taurus_RNF43
--------------------------------------------------------------------------------
-----------------------MSGGHQLQLAALWPWLLMATLQAGFGR-----------------------------T
GLVLAAAVESERSAEQKAIIR-----------VIPLKMDPTGKLNLTLEGVFAGVAEITP--AEGKLMQS--HPLYLCNA
SDDDNLEPG-FISIVKLESPQRAPRP-CLSLASKARMAGERGASAVLFDITEDRAAAEQLQQP--LGLTWPVVLIWGHDA
EKLMEFVYKNRKAHVRIELK----EPP-TWPD------------------------YDVWILLTVVGIIFVVILALVLRI
RCRPRHSRPDPLQQRTAWAISQLATRSYRAG-CRGARKEWPDSGSSCSS------------------------APVCAIC
LEEFSEGQELRVISC-LHEFHRTCVDPWLHQHRT----CPLCMFNIVEGD-------------SLSQSLGPSRAYQ----
-------------EPGRRLHLIRQHPGHAHYHLPAAYLLGPSRS-AVARPTRPGPFLPSQ---EPGV----GARHHRQPR
TTHP--------------RAPGEPQRLAVAP--RPYAPGWGLSHLR-CTSQH-----------------PA-TCPAP---
-----------------------------PRRTRPHDSSGSGESYR---TERSGYLADGPASDSSS------------GP
CHGSSSDSVVNCTDVSLQGIHGSSSTFRSSLSSDFDPLVYCSPE------------------------------------
-------GEPPGKAAQPSMAS---RPRSLDSVVP-------VGETQVSSHIHYHRHRHHHYRRRF-----RWHGRKADPE
TAVPPSRPAVPRTQLQPEPPSPDLHATRCSPAALSGQPPAPQRPRALTEPAPGPPDASSSSP----AASSLFHLQKSSLS
VRHPQRRRRGGPLEPTPASRSQDLTTHPTCQIFPHYGPSLAHPWSPEAHPLFFGHPGLERRLLPEAPGPTYPSSQPVWLC
LTPRQALGPHPSGEGPSAWSSGNPEGRPCPYPHCQVLPAQPGTEEE-LEELCEQAV------------------------
-
>Loxodonta_africana_RNF43
--------------------------------------------------------------------------------
-----------------------MSGGHQLQLAALWPWLLMATLQAGFGR-----------------------------T
GLVLAAAVESERSTEQKAIIR-----------VIPLKMDPTGKLNLTLEGVFAGVAEITP--AEGKLMQS--HPLYLCNA
SDDDNLEPG-FISIVKLESPRRAPRP-CLSLASKARMAGERGASAVLFDITEDRAAAEQLQQP--LGLTWPVVLIWGNDA
EKLMEFVYKNRKAHVRIELK----EPP-AWPD------------------------YDVWILLTVVGTIFVVILASVLRI
RCRPHHSRPEPLQQRTAWAISQLATRRYRAS-CKRARAEWPDSGSSCSS------------------------APMCAIC
LEEFSEGQELRVISC-LHEFHRTCVDPWLHQHRT----CPLCMFNIVEGD-------------SFSQPLGPSRPYQ----
-------------EPGRRLHLIRQHPGHAHYHFPAAYLLGPSRSSSVVRPPRPGPFLPSQ---EPGS----GPRHHRLPR
GAHP--------------RPVGEQQCLAMAQ--LPYAQGWGLSRLR-CTSQH-----------------PA-ACPVP---
-----------------------------PRRARPHDSSGSGESYC---TERSGYLADGPASDSSS------------GP
CHGSSSDSVVNCTDISLQGVHGSSSTFRSSLSSDFDPLVYCSPE------------------------------------
-------GEPQKEEPHVSVAS---RPRSLDSVVP-------SGETQVSSHIHYHRHRHHHYKKRF-----QWHGRKAGPE
TGHPQSRPGVPRTQLQLEPTSPDEQAARSTSPAPSGQLPSPQRPKAITEPAPGPAEASSPSS----IPSSLLSLQKSSHP
ARHPQRKRRGGPSEPTPVSQPQDLTAHPGCRMFPHYGPRLAYPWSPEAHPLIFGPSGLDRRLLPETPAPHYSSSQPVWLC
LTPRLPLGPHPPEEGSSEWSPGTTEGRPCPYPHCQVLPAQPGSEEEELEVLCEQAV------------------------
-
>Gallus_gallus_RNF43
--------------------------------------------------------------------------------
-----------------------MSGGPQLQLVVLWPWLLMASLQAGLGR-----------------------------T
GLALAAAVESERTAVQKAIIR-----------VIPLKVEPI-----VLEGEFASVAEVTP--AEGKLLQS--HPLSLCNT
SEDEHTESG-FITIVKLEQPDRDPNP-CLSLANKAKLAGERGARAILFDITDDESAADQLKKP--RGLSQPVVLIRGHDA
ELLMGVVNKNREAHVKIEVK----EPP-AWPD------------------------YDVWILLTVVSTVVVIILIFVVRT
KCQLNR-TQDSVQQQTMQAIGQLATRRYQAR-CRQAS--WWDSASSCSS------------------------APVCAIC
LEEFTEGQELRIISC-SHEFHRECVDPWLQQHHT----CPLCMFNILARD-------------SVDQATVAGSRLAP---
----------RDMEPGRRLHLFRQHPGHSLYHLPHPYPQRNLRS-FPSEPAHSNPFFHSP---ELS--------------
------------------------QLLRGQQHPNPPACGQ--PPHRTCSLQP-----------------TP-PCLGLKAA
LAQRQHRAPVPR---------------RGVSHGHQHNSSGSGESYL---TEHSGYLADGPGSDSSS------------GP
CHGSSSDSVLNCTDISLQGIHGSCSTFRSSLSSDYDPFVYCSSD------------------------------------
-------GPTMDNGPERQRALRETRPRSLDLMVPGGA---APAKAQVLNHIHYHHHQHHHYRRDV-----ECPPGRAGPG
PGQRKSRY--SGAKPLESRTELQEAPPVGQPASPQQGREPPHAPSASPNRLDFGVDANRQSGA--AGTSPVLLPQRHSLQ
SRH-HRRKRKCPLELDPALLPEDSALP---NHIPHSHP-AGHRCSPEVQP-----------LIPSSPMPCSTGSRPLWKC
LVP-----------------------------------------------------------------------------
-
>Anolis_carolinensis_RNF43
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------MTG--------FELTS------------------PPLLIFSQ--
-----------------------------QSN------------------------YDLWILLTVVSTVLVIILIFIVRT
RCQPRR-NQAHAQEETLQAINQLATRRYQSR-RRRPGAPNGDSASSCSS------------------------APVCAIC
LEEFSEGQELRIITC-FHEFHRCCVDPWLKEHQT----CPLCMFNIVGPP-------------ERPAQRPTNHSRRRAFG
GRIRHPFPKTSRFHPQGELLLYCPLVAVLPHSFPRVLLAVLCVGEQNFGAPQKNNHMCRAR--PPSCGDMREASHKDGKN
IKNI--------------RASPGQHPCRRPILSLQKQLRLLLTHTKNSKTRHK--------------VIPAGSCPKPGGP
PVAGVFGVRSAAGLPLPERQGLLAPAPVRLPPGSPGNPCCQSESCHGAPSEPSGYLPDGPGSDSSS------------GP
CHGSSSDSILNCTDVSLTAIHGSCSTFRSSLSSDYDPFAF----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Tetraodon_nigroviridis_RNF43_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---MSLVNRNEEAIVRINIM----LNPPRWPH------------------------YDVGIVLTIVLAILTIILIFALRY
KCRSNR-TWDSVHQQTRQAISRLETKTYNSQGCSGSHRQRAPWGSASSSNS----------------------SPICAIC
LEEFQDGQHLRIISC-AHEFHKDCVDPWLLQHRT----CPLCMHNIM---------------------------------
-------------EQSQGFLHHHP-TVAQGTTPSLNMLPFGPGCGYHRPAEG--PGRPHRFGSNCR-----NSAHHYAPR
R------------------SCHNYRSSCPAQ---RSASSSRLYHGP-SAGPQ-----------------PR-RAPG----
-------------------------------HSRQGDGSCSGGSYH---TERSGYLADGPASDSSS------------GP
CHGSSSDSVLNCTDVSLQGVYGSWSTFRSSLSSDYDPFVYYGPG------------------------------------
-------NGHSAARRSSLDTCAQTRPRSLDSVENKMGCPEEPQPQTVFNHVHYHRHRHHHYEEEE-----HSQGPVRGSD
EELG---------------------ATAAAPAALGLDTDSPVTLKHSPCLCPNPEPTDRPSPGT----DCQD--------
------RDPG-----SPTGLRL----------------------------------------------------------
--------------------------------------------------------------------------------
-
>Oryzias_latipes_RNF43_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------QARMALDKGAQAVIFDVSDDANAAAELREA--NSFSRPVVLVEAQGA
EDLMGLVNKNEEANVVIEIK----VEP-KWLH------------------------YDVSILLTIILVIFTIVLIFVFRY
KCKSNR-TWDSVHQQTVQAINRLETKTYSTQNCSGSQRHRGAWGSASSSNS----------------------SPVCAIC
LEEFQDGQHLRIISC-AHEFHKACVDPWLLQHRT----CPLCMHNIMAQ-------------------------------
----------QNSEQSQGFLHSQPYSNPQHHPFPQHAIPFSMRPLYPHGLSGPYPNLGHYSGSSPMD----TQTLHFLSS
RQLG--------------AGCGYHHPAEVPG---RPHRTGGSCRTP-THHYT-----------------PR-RSCHNYRS
FCPAQ------------------------RTRSRQDEASCSGGSYH---TDRSGYFPDGPASDSSS------------GP
CHGSSSDSVLNCTDVSLQGVYGSWSTFRSSLSSDYDPFVYYGPG------------------------------------
-------AGR-LPNTNSPEVSSQVRPRSLDSVVNKAGSPEE-QPQTVS--IHYHRHRHHHYEE-----------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Takifugu_rubripes_RNF43_b
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------ARMALDKGAQAVIFDVSDDADAAAELREA--DSLPRPVVMVESDDA
EELMALVNKNEEAVVRIEIM----VNPPRWPH------------------------YDMGIVLTIVLAVLTIVLIFALRY
KCRSSR-TWDSVHQQTRQAISRLETKTYNSQGCSGPHHQRAPWGSASSSNS----------------------SPVCAIC
LEEFQDGQHLRIISC-AHEFHKDCVDPWLLQHRT----CPLCMHNIMALG-------------TSCLWLPPPGTERQAQR
------FRLQQSSEQSQGFLHHHPYSGPRNHHFPQHAVPFSLRPQYPCGPSGPYPDLGHYNGSSPR-----TSSHHYGPR
R------------------SCHTYRSSCPAQ---RSASSSRLYHGP-SVGPQ-----------------PR-RTLG----
-------------------------------HGRQGEGSCSGGSYH---TERSGYLADGPASDSSS------------GP
CHGSSSDSVLNCTDVSLQGVYGSWSTFRSSLSSDYDPFVYYGPG------------------------------------
-------NGHSAARRSSLDTCAQTRPRSLDSVENKAVCPEEQQPQTVFNHIHYHRHRHHHYEEEE-----HSQSPARGSE
EELG---------------------ATAAAPAALSLDKDSPE---HSPCLCPNPDRTG-PAGGP----QHPHPLWSESRF
LLPPARAAPGPAACPSSSGLRN----------------------------------------------------------
--------------------------------------------------------------------------------
-
>Ciona_intestinalis_RNF43
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------QIHPLSLCNV
VGDDQLYEYGWVGVVELGPSYLEPRP-CLSVYGKAKRALEKGATAVIFDITNQPDAVSQLSSEYYERLDRPIVLVQGQSA
FHLINLIRDQQVARARIQSGVPTKSEDQYNQY------------------------FNMAVFMGCFVVVFVICIVLLIKL
KCWRRE-RSVSMANIASETLRRMKTRKFRVDPRKQWTDDC------SNTS-----------------------EQLCAIC
LEVFNENEELRVIPC-SHEFHKHCVDPWLKEKLT----CPLCNFNILGDP-----------------PNLQRRSRQIS--
------------------SPSVTSRSTIHVTPRRQIFNDYNGYEEGRYENNCPPYESCYTGSRHTNAYYGGHFTELFCDA
PNGA----------------QILQNNKFDVVPCVGTVVPHNHYFRRRQPTPH----------------------------
---------------FYDRSAIPNGASAYQPQRENVGISEFLPKPTNREELSSGSFATPKQLTNFDLPPAYES----LET
SRNLPEYCATQTCVTPPYRSIRGCTLYRR-SSGTNTNYRN----------------------------------------
-----------AHNTYMPELDLDSRPVSLRSGYLPDSDGVS--DKVDTTPYLFGPFSVTTTTQCV---------CVVTDT
TCCVTDTSVRSVFGSSLISDAPAPPCDS--ILKIPHRSSTPCIGYSSSDAEVGARISVSSLEG--VLESVSVPTVYDDAV
NY----------DEIWFDDVMVNDVTSSTSPRLTKHNRAGH--VTTSTNHAADKVTRCAV--------------------
--------------------------------------------------------------------------------
-
>Homo_sapiens_RNF128
--------------------------------------------------------------------------------
-------------------MGPPPGAGVSCRGGCGFSRLLAWCFLLALS-----------------------PQAPGSRG
AEAVWTAYLNVSWRVPHTG----------VNRTVWELSEEGVYGQDSPLEPVAGVLVPPDG----PGALNACNPHTNFTV
PTV-----WGSTVQVSWLALIQRGGG-CTFADKIH-LAYERGASGAVIFNFPG-TRNEVIPMSHPGAVDIVAIMIGNLKG
TKILQSI-QRGIQVTMVIEVG-KKHGPWV---------------------------NHYSIFFVSVSFFIITAATVGYFI
FYSARR--LRNARAQSRKQ-RQLKADAKKAIGRLQLRTLKQGDKEIGPD------------------------GDSCAVC
IELYKPNDLVRILTC-NHIFHKTCVDPWLLEHRT----CPMCKCDILKAL------------------------------
---------GIEVDVEDGS-VSLQVPVSNEISN----------------SASSHEEDNRS--------------------
--------------------------------------------------------------------------------
--------------------------------------------ETASSGYASVQGTDEPPLEEHVQSTNESLQLVNHEA
-NSVAVDVIPHVDNPTFEEDETPNQETAVREIKS----------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Mus_musculus_RNF128
--------------------------------------------------------------------------------
-------------------MGPPPGIGVYCRGGCGAARLLAWCFLLALS-----------------------PHAPGSRG
AEAVWTAYLNVSWRVPHTG----------VNRTVWELSEEGVYGQDSPLEPVSGVLVPPDG----PGALNACNPHTNFTV
PTV-----WGSTVQVSWLALIQRGGG-CTFADKIH-LASERGASGAVIFNFPG-TRNEVIPMSHPGAGDIVAIMIGNLKG
TKILQSI-QRGIQVTMVIEVG-KKHGPWV---------------------------NHYSIFFVSVSFFIITAATVGYFI
FYSARR--LRNARAQSRKQ-RQLKADAKKAIGKLQLRTLKQGDKEIGPD------------------------GDSCAVC
IELYKPNDLVRILTC-NHIFHKTCVDPWLLEHRT----CPMCKCDILKAL------------------------------
---------GIEVDVEDGS-VSLQVPVSNEASN----------------TASPHEEDSRS--------------------
--------------------------------------------------------------------------------
--------------------------------------------ETASSGYASVQGADEPPLEEHAQSANENLQLVNHEA
-NSVAVDVVPHVDNPTFEEDETPDQEAAVREIKS----------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Pan_troglodytes_RNF128
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------SNTKKPWIALIERGN--CTFSEKIQ-MAYERGASGAVIFNFPG-TRNEVIPMSHPGAVDIVAIMIGNLKG
TKILQSI-QRGIQVTMVIEVG-KKHGPWV---------------------------NHYSIFFVSVSFFIITAATVGYFI
FYSARR--LRNARAQSRKQ-RQLKADAKKAIGRLQLRTLKQGDKEIGPD------------------------GDSCAVC
IELYKPNDLVRILTC-NHIFHKTCVDPWLLEHRT----CPMCKCDILKAL------------------------------
---------GIEVDVEDGS-VSLQVPVSNEISN----------------SASSHEEDNRS--------------------
--------------------------------------------------------------------------------
--------------------------------------------ETASSGYASVQGTDEPPLEEHVQSTNENLQLVNHEA
-NSVAVDVIPHVDNPTFEEDETPNQETAVREIKS----------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Gorilla_gorilla_RNF128
--------------------------------------------------------------------------------
-------------------MGPPPRAGVSCRGGCGSSRLLAWCFLLALS-----------------------PQAPGSRG
AEAVWTAYLNVSWRVPHTG----------VNRTVWELSEEGVYGQDSPLEPVSGVLVPPDG----PGALNACNPHTNFTV
PTV-----WGSTVQVSWLALIQRGGG-CTFADKIH-LAYERGASGAVIFNFPG-TRNEVIPMSHPGAGDIVAIMIGNLKG
TKILQSI-QRGIQVTMVIEVG-KKHGPWV---------------------------NHYSIFFVSVSFFIITAATVGYFI
FYSARR--LRNARAQSRKQ-RQLKADAKKAIGRLQLRTLKQGDKEIGPD------------------------GDSCAVC
IELYKPNDLVRILTC-NHIFHKTCVDPWLLEHRT----CPMCKCDILKAL------------------------------
---------GIEVDVEDGS-VSLQVPVSNETSN----------------SASSHEEDNRS--------------------
--------------------------------------------------------------------------------
--------------------------------------------ETASSGYASVQGADEPPLEEHVQSTNENLQLVNHEA
-NSVSVDVVPHVDNPTFEEDETPDQETAVREIKS----------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Rattus_norvegicus_RNF128
--------------------------------------------------------------------------------
-------------------MGPPPGIGVYCRGGCGAARLLAWCFLLALS-----------------------PHAPGSRG
AEAVWTAYLNVSWRVPHPG----------VNRTVWELSEEGVYGQDSPLEPVSGVLVPPDG----PGALNACNPHTNFTV
PTV-----WGSTVQVSWLALIQRGGG-CTFADKIH-LAYERGASGAVIFNFPG-TRNEVIPMSHPGAGDIVAIMIGNLKG
TKILQSI-QRGIQVTMVIEVG-KKHGPWV---------------------------NHYSIFFVSVSFFIITAATVGYFI
FYSARR--LRNARAQSRKQ-RQLKADAKKAIGRLQLRTLKQGDKEIGPD------------------------GDSCAVC
IELYKPNDVVRILTC-NHIFHKTCVDPWLLEHRT----CPMCKCDILKAL------------------------------
---------GIEVDVEDGS-VSLQVPVSNEASN----------------TASPHEEDNRS--------------------
--------------------------------------------------------------------------------
--------------------------------------------ETASSGYASVQGADEPPLEEHAQSANENLQLVNHEA
-NSVAVDVVPHVDNPTFEEDETPDQEMAVREVKS----------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Bos_taurus_RNF128
--------------------------------------------------------------------------------
-------------------MGQLPGAGVFCRGGCGFSRLLAWCFLLVLS-----------------------PQTPGSRG
AEAVWTAYLNVSWRVPHTG----------VNRTVWELSEEGVYGQDSPLEPVAGVLVPPDG----PGALNACNPHTNFTV
PTVPGD--WGSSVQVSWLALIQRGGG-CTFADKIH-LAYERGASGAVIFNFPG-TRNEVIPMSHPGAGDIVAIMIGNLKG
TKILQSI-QRGIQVTMVIEVG-KKHGPWV---------------------------NHYSIFFVSVSFFIITAATVGYFI
FYSARR--LRNARAQSRKQ-RQLKADAKKAIGRLQLRTLKQGDKEIGPD------------------------GDSCAVC
IELYKPNDLVRILTC-NHVFHKTCVDPWLLEHRT----CPMCKCDILKAL------------------------------
---------GIEVDVEDGS-VSLQVPVSNETSS----------------NASPHEEDNRS--------------------
--------------------------------------------------------------------------------
--------------------------------------------ETASSGYASVQGADEPPLEEHAHSANENLQLVNHEA
-NSMAVDVVPHVDNPTFEEDESPDQETTVREIKS----------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Loxodonta_africana_RNF128
--------------------------------------------------------------------------------
-------------------MGPPPATGVSCRGGCGSSRLLAWCFLLALS-----------------------PHAPGCRG
AEAVWTAYLNVSWWVPHTG----------VNRTVWELSEEGVYGQDSPLEPVAGVLVPPDG----PGALNACNPHTNFTV
PTVPGD--WGNNVQVSWLALIQRGGG-CTFADKIH-LAYERGASGAVIFNFPG-TRNEVIPMSHPGAGDIVAIMIGNLKG
TKILQSI-QKGIQVTMVIEVG-KKHGPWV---------------------------NHYSIFFVSVSFFIITAATVGYFI
FYSARR--LRNARAQSRKQ-RQLKADAKKAIGRLQLRTLKQGDEEIGPD------------------------GDSCAVC
IELYKPNDLVRILTC-NHIFHKTCVDPWLLEHRT----CPMCKCDILKAL------------------------------
---------GIEVDVEDGS-VSLQVPVSSETSN----------------STSPHEEDNRS--------------------
--------------------------------------------------------------------------------
--------------------------------------------ETASSGYASVQGADEPPLEEHVQSANENLQLVNHEA
-SSMAVDVVPHVDNPTFEEDETPDQEAAVREIKS----------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Gallus_gallus_RNF128
--------------------------------------------------------------------------------
--------------------------------MKQENKFSPVCFLVIVG-----------------------VLFR----
TTETTAERAFVSLLYFNST----------SNRSASEQCECGLYGLNSPLLSAQGFVAIPK-----AASLQACDWNTQFT-
-----------ITEPPWIALIERGN--CTFAEKIK-VAARRGATAAVIYNAPA-KRNYPIPMSHIGAGSIVAIMIGNLKG
MEILRRI-ESGLKVTMVIEVG-KKHGPWM---------------------------NHYSIFFVSVSFFIVTAATVGYFI
FYSARR--FRITRAQSRKQ-RQLKAEAKKAIGQLQLRTLKQGDKETGPD------------------------GDSCAVC
IELYKPNEVVRILTC-NHLFHKNCIDPWLLEHRT----CPMCKCDILKVL------------------------------
---------GVEVDAEDGA-ESVQATVSSGTSN----------------ITSINEMDSHS--------------------
--------------------------------------------------------------------------------
--------------------------------------------ETASSGYASVQGADESVLEEHAPSENDNTHLVNNES
-QTSAVTVLPPLDNPTFEADET-----QVSEVRS----------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Anolis_carolinensis_RNF128
--------------------------------------------------------------------------------
-------MKSFPRGLGGKSVWRTEAAGSGCSCCCRRACAVAGAAFAEVNSAVGDAGVRGGAG----------PGSPPSGG
GGLLPYGVVGVAERVVVPG----------RERERERVERGRERPVRAGLASAGAWGRVAVP----EGALEACGAHVNFSG
GAAG-------LPEPPWLALVRRGGG-CTFSQKIN-AAALSGAKAAVVFNAPGGQGNEVQVMIHPGTGNTVAIMISYLKG
KEILRKM-EQGYQVTMFIEVG-KKHGPWM---------------------------NNYSIFFVSVSFFIVTAATVGYFI
FYSARR--LRIARAQNRKQ-RRLKADAKKAISQLQLRTLKQGDKETGPD------------------------ADSCAVC
IEVYKPNDVVRILTC-NHLFHKNCIDPWLLEHRT----CPMCKCDILKAL------------------------------
---------GIEVDIEDGA-ESIQPTEPSNIP-----------------SVP--EEDNHS--------------------
--------------------------------------------------------------------------------
--------------------------------------------ETASSGYASVQGADEPVPEEPAHSESDNLQLVNNNA
LQPPPVDVLPHLDNPAFEADEAHVQEAKS---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Xenopus_tropicalis_RNF128
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------GTKDTVAIMIGNIKG
NEIVEVI-KGGMQVMMVIEVG-RKHGSWI---------------------------NHYSIFFVSVSFFIVTAATVGYFI
FYSARR--WRLTRAQNKKM-KQLKAEAKKAIGKLQLRTIKQGDKVMSRDY-----------------------AFGCTLC
LRKWAFIIIIILHTCSNHFFHKNCIDPWLLEHRT----CPMCKCDILKSL------------------------------
---------GIAEDEEETT-SAAIPSVSSELQRS---------------TVQTIEEENRS--------------------
--------------------------------------------------------------------------------
--------------------------------------------ETASSGYASVRGGDEPVDEG----------------
---------QHI--------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Homo_sapiens_RNF130
--------------------------------------------------------------------------------
-----------------------MSCAGR-AGPARLAALALLTCSLWPAR------------------------ADN--A
SQEYYTALINVTVQEP------------GRGAPLTFRIDRGRYGLDSPKAEVRGQVLAPLP-LHGVADHLGCDPQTRFFV
PPNIK----------QWIALLQRGN--CTFKEKIS-RAAFHNAVAVVIYNNK--SKEEPVTMTHPGTGDIIAVMITELRG
KDILSYL-EKNISVQMTIAVGTRMPPKNF---------------------------SRGSLVFVSISFIVLMIISSAWLI
FYFIQK--IRYTNARDRNQ-RRLGDAAKKAISKLTTRTVKKGDKETDPD------------------------FDHCAVC
IESYKQNDVVRILPC-KHVFHKSCVDPWLSEHCT----CPMCKLNILKAL------------------------------
---------GIVPNLPCTDNVAFDMERLTRTQAVN-----------RRSALGDLAGDNSL--------------------
--------------------------------------------------------------------------------
--------------------------------------------GLEP-LRTSGISPLPQDGELTPRT-GEINIAVTKEW
FIIASFG-----LLSALTLCYMIIR-ATASLNANEVEWF-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Mus_musculus_RNF130
--------------------------------------------------------------------------------
-----------------------MSGAAR-AGPARLAALALLTCSLWPTR------------------------ADN--A
SQEYYTALINVTVQEP------------GRGTPLTFRIDRGRYGLDSPKAEVRGQVLAPLP-IHGVADHLGCDPQTRFFV
PPNIK----------QWIALLQRGN--CTFKEKIS-RAAFHNAVAVVIYNNK--SKEEPVTMTHPGTGDIIAVMITELRG
KDILSYL-EKNISVQMTIAVGTRMPPKNF---------------------------SRGSLVFVSISFIVLMIISSAWLI
FYFIQK--IRYTNARDRNQ-RRLGDAAKKAISKLTTRTVKKGDKETDPD------------------------FDHCAVC
IESYKQNDVVRVLPC-KHVFHKSCVDPWLSEHCT----CPMCKLNILKAL------------------------------
---------GIVPNLPCTDNVAFDMERLTRTQAVN-----------RRAALGDLAGDSSL--------------------
--------------------------------------------------------------------------------
--------------------------------------------GLEP-LRTSGISPLPQDGELTPRT-GEINIAVTKEW
FIIASFG-----LLSALTLCYMIIR-ATASLNANEVEWF-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Pan_troglodytes_RNF130
--------------------------------------------------------------------------------
-----------------------MSCAGR-AGPARLAALALLTCSLWPAR------------------------ADN--A
SQEYYTALINVTVQEP------------GRGAPLTFRIDRGRYGLDSPKAEVRGQVLAPLP-LHGVADHLGCDPQTRFFV
PPNIK----------QWIALLQRGN--CTFKEKIS-RAAFHNAVAVVIYNNK--SKEEPVTMTHPGTGDIIAVMITELRG
KDILSYL-EKNISVQMTIAVGTRMPPKNF---------------------------SRGSLVFVSISFIVLMIISSAWLI
FYFIQK--IRYTNARDRNQ-RRLGDAAKKAISKLTTRTVKKGDKETDPD------------------------FDHCAVC
IESYKQNDVVRILPC-KHVFHKSCVDPWLSEHCT----CPMCKLNILKAL------------------------------
---------GIVPNLPCTDNVAFDMERLTRTQAVN-----------RRSALGDLAGDNSL--------------------
--------------------------------------------------------------------------------
--------------------------------------------GLEP-LRTSGISPLPQDGELTPRT-GEINIAVTKEW
FIIASFG-----LLSALTLCYMIIR-ATASLNANEVEWF-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Gorilla_gorilla_RNF130
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------ADHLGCDPQTRFFV
PPNIK----------QWIALLQRGN--CTFKEKIS-RAAFHNAVAVVIYNNK--SKEEPVTMTHPGTGDIIAVMITELRG
KDILSYL-EKNISVQMTIAVGTRMPPKNF---------------------------SRGSLVFVSISFIVLMIISSAWLI
FYFIQK--IRYTNARDRNQ-RRLGDAAKKAISKLTTRTVKKGDKETDPD------------------------FDHCAVC
IESYKQNDVVRILPC-KHVFHKSCVDPWLSEHCT----CPMCKLNILKAL------------------------------
---------GIVPNLPCTDNVAFDMERLTRTQAVN-----------RRSALGDLAGDNSL--------------------
--------------------------------------------------------------------------------
--------------------------------------------GLEP-LRTSGISPLPQDGELTPRT-GEINIAVTKEW
FIIASFG-----LLSALTLCYMIIR-ATASLNANEVEWF-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Macaca_mulatta_RNF130
--------------------------------------------------------------------------------
-----------------------------------------XTCSLWPAR------------------------ADN--A
SQEYYTALINVTVQEP------------GRGAPLTFRIDRGRYGLDSPKAEVRGQVLAPLP-LHG-GEHTGSERERHIFA
TVLCG----------HLLALLPRLE--C---KKIS-RAAFHNAVAVVIYNNK--SKEEPVTMTHPGTGDIIAVMITELRG
KDILSYL-EKNISVQMTIAVGTRMPPKNF---------------------------SRGSLVFVSISFIVLMIISSAWLI
FYFIQK--IRYTNARDRNQ-RRLGDAAKKAISKLTTRTVKKGDKETDPD------------------------FDHCAVC
IESYKQNDVVRILPC-KHVFHKSCVDPWLSEHCT----CPMCKLNILKAL------------------------------
---------GIVPNLPCTDNVAFDMERLTRTQAVN-----------RRSALGDLAGDNSL--------------------
--------------------------------------------------------------------------------
--------------------------------------------GLEP-LRTSGISPLPQDGELTPRT-GEINIAVTKEW
FIIASFG-----LLSALTLCYMIIR-ATASLNANE---------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Bos_taurus_RNF130
--------------------------------------------------------------------------------
------------------------GGEAR-AGPARLAAFALLTCSLWPAR------------------------ADN--A
SQEYYTALINVTVQEP------------GRGAPLTFRIDRGRYGLDSPKAEVRGQVLAPLP-IHGVADHLGCDPQTRFFV
PPNIK----------QWIALLQRGN--CTFKEKIS-RAAFHNAVAVVIYNNK--SKEEPVTMTHPGTGDIIAVMITELRG
KDILSYL-EKNISVQMTIAVGTRMPPKNF---------------------------SRGSLVFVSISFIVLMIISSAWLI
FYFIQK--IRYTNARDRNQ-RRLGDAAKKAISKLTTRTVKKGDKETDPD------------------------FDHCAVC
IESYKQNDVVRILPC-KHVFHKSCVDPWLSEHCT----CPMCKLNILKAL------------------------------
---------GIVPNLPCTDNVAFDMERLTRTQAVN-----------RRSALGELASDNSL--------------------
--------------------------------------------------------------------------------
--------------------------------------------GLEP-LRTSGISPLPQDGELTPRT-GEINIAVTKEW
FIIASFG-----LLSALTLCYMIIR-ATASLNANEIQWF-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Loxodonta_africana_RNF130
--------------------------------------------------------------------------------
-----------------------MGGAAR-AGPGRLAALALLTCSVWPAR------------------------ADN--A
SQEYYTALINVTVQEP------------GRGAPLTFRIDRGRYGLDSPKAEVRGQVLAPLP-IHGVADHLGCDPQTRFFV
PPNIK----------QWIALLQRGN--CTFKEKIS-RAAFHNAVAVVIYNNK--SKEEPVTMTHPGTGDIIAVMITELRG
KDILSYL-EKNISVQMTIAVGARMPPKNF---------------------------SRGSLVFVSISFIVLMIISSAWLI
FYFIQK--IRYTNARDRNQ-RRLGDAAKKAISKLTTRTVKKGDKETDPD------------------------FDHCAVC
IESYKQNDVVRILPC-KHVFHKSCVDPWLSEHCT----CPMCKLNILKAL------------------------------
---------GIVPNLPCTDNVAFDMERLTRTQAVN-----------RRSALSDLASDSSL--------------------
--------------------------------------------------------------------------------
--------------------------------------------GLEP-LRTSGISPLPQDGELTPRT-GEINIAVTKEW
FIIASFG-----LLSALTLCYMIIR-ATASLNANE---------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Gallus_gallus_RNF130
--------------------------------------------------------------------------------
--------------------MGPRWARRRRSGGGSALLLLLGHCWLWAAG------------------------ADDNGS
QLSYYTALINVTVLSP------------ERGGPTLLRIDRGRYGQDSPKVEVKGLLVTPVP-INGVADRLGCDPRTRFQV
PPNTK----------QWIALLQRGN--CTFREKIL-RAASHNATAVVIYNNI--SSEEPVTMTHQGTGDIVAVMITESKV
KEILNYL-EKNISVLMAIAVGSRVPLKNF---------------------------SRGSLVFVSISFIVLMIISSAWLI
FYFIQK--IRYTSARDRNQ-RRLGDAAKKAVGKLTTRTVKKGDKETDPD------------------------FDHCAVC
IESYKQNDVVRILPC-KHVFHKACVDPWLSEHCT----CPMCKLNILKAL------------------------------
---------GIVPNVPCTENVAFDMERLSRSQPAS-----------RRSALGDFANDSSL--------------------
--------------------------------------------------------------------------------
--------------------------------------------SLEP-LRTSGMSQLPQDGELTPRS-GEINIAVTKEW
FIIASFG-----LLSALTLCYMIIK-ATASLNANEAEWY-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Taeniopygia_guttata_RNF130
--------------------------------------------------------------------------------
--------------------------------------LLLWHGRVRPAG------------------------ADN--A
SQAYYTALINVTVLSP------------ERGGPTLLRIDRGRYGQDSPKVEVKGLLVAPVP-INGVADRLGCDPRTRFQV
PPNTK----------QWIALLQRGN--CTFKEKIL-RAASHNATAVVIYNNV--SSEEPVTMTHQGTGDIVAVMITESKV
KEILNYL-EKNISVLMAIAVGSRVPPKNF---------------------------SRGSLVFVSISFIVLMIISSAWLI
FYFIQK--IRYTSARDRNQ-RRLGDAAKKAIGKLTTRTVKKGDKETDPD------------------------FDHCAVC
IESYKQNDVVRILPC-KHVFHKVCVDPWLSEHCT----CPMCKLNILKAL------------------------------
---------GIVPNVPCTDNVAFDMERLTRGQPAS-----------RRSALGDFGTDSSL--------------------
--------------------------------------------------------------------------------
--------------------------------------------SLEP-LRTSGMSQLPQDGELTPRS-GEINIAVTKEW
FIIASFG-----LLSALTLCYMIIK-ATASLNANE---------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Anolis_carolinensis_RNF130
--------------------------------------------------------------------------------
--------------------------------------LVVLNCYALLAS------------------------ADN--T
NQAYYTAFLNVTVLNP------------ERS----AFLIRGRYGQDSPKRGVTGLLLAPLP-INGVVDRLGCDQRTRFQV
PPNTK----------QWIALLQRGN--CTFKQKIM-RAALQNASAVVIYNNV--SGEEPVTMTHQGTGDIVTVMITELKV
KEILTYL-EKNMSVLIAIAVGTRSQNKNF---------------------------SRSSLVFVSISFIVLMIISSAWLI
FYFIQK--IRYTSARDRNQ-RRLGDAAKKAVGKLTTRTVKKGDKETDPD------------------------FDHCAVC
IESYKQNDVVRILPC-KHVFHKTCVDPWLSEHCT----CPMCKLNILKAL------------------------------
---------GIVTNVPCADNMAFDMERLTRGQLGN-----------RRSVLGDFSSDTSL--------------------
--------------------------------------------------------------------------------
--------------------------------------------TLEP-LRTSGISQFPQDGELTPRT-GEINIAVTKEW
FIIASFG-----LLSALTLCYMIIK-ATASLNADEAEWY-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Xenopus_tropicalis_RNF130
--------------------------------------------------------------------------------
------------------QTGLKMIPRRSLQYLNCLPILVLFPCSMVQSG------------------------SDT--A
NMENYSALVNVTIQDP------------SSN-PVLLRIDGGRYGLDSPKTEAKGLLLTPVH-IHGAADRLGCDPQTRFNV
PPNTK----------HWIALLQRGN--CTFKEKIL-RAASHNASAVVIYNNN--SKEETVTMTHQGTGEIVAIMISEARG
REILSYV-ERNISVLMAIAVGSRNQHKNF---------------------------SRGSLVFVSISFIVLMIISSAWLI
FYFIQK--IRYTSARDRNQ-RRLGDAAKKAIGKLTTRTVKKGDKETDPD------------------------FDHCAVC
IESYKQNDIVRVLPC-KHVFHKVCVDPWLSEHCT----CPMCKLNILKAL------------------------------
---------GIAANVPCTDNVAFDMERLTRSQPPS-----------RRSAPNDPTEEGSL--------------------
--------------------------------------------------------------------------------
--------------------------------------------SLES-LRSSRISQGPHDVEAIPRT-GEINISVTKEW
FIIASFG-----LLSALTLCYMIIK-ATASLYATEVEWS-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Danio_rerio_RNF130_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------AVDLQGCCPHTRFIV
PPKTT----------HWVAIMQRGK--CTFKEKIL-KAAAFNASAVIIYNNN--TKEDTVTMAHEGTGDIVAVMITESFG
KEILGFL-EKNQTVLVSVIVGSRGMPKNI---------------------------NRGSLVFVSISFIVLMIISSAWLI
FYFIQK--IRDTSARDRSQ-RRLGDAAKKAISKLTTRTVKRGDKETEPD------------------------FNHCAVC
IEGYQLNDVVRILPC-KHVFHKMCVDPWLNEHCT----CPMCKLNILKAL------------------------------
---------GVMPNLPCVDNMAFDMDRMSRSQTSS-----------QRTALVDLSSETSI--------------------
--------------------------------------------------------------------------------
--------------------------------------------SLEP-LRHSSSSQLPSDEELIPRS-GEINIAVTTGH
FFNRNS------VSPRSVVCEMELPDIQASLDMYDDNKS-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Tetraodon_nigroviridis_RNF130_a
--------------------------------------------------------------------------------
---------------------TVGALAAGSRGASMSSLSCSQPSSALAAR------------------------SDRGVV
PEEHVGATVNATVLDG------------RGNVVQVMSSVDGRYGQNSPKVDARGVVLTPAP-RNGVVDRQGCDPATRFLV
PARTV----------QWVALLQRGN--CTFKEKIL-KAASFNATAVLIYNN---FTEKTVMMGHEGTGDTVAVMITEAFG
KELLAHL-DRNLTVLVSVLFR---PTKNI---------------------------NRGSLVFVSISFIVLMIISTAWFI
FYFIQK--IGSRSSQHRGQ-RHLGDAAKKAIGKLSTRTVKKGDKETHPD------------------------FNHCAVC
IEAYQLNDVVRILPC-KHVFHKVCVDPWLNEHCT----CPICKLNILKAL------------------------------
---------GITTSVPCVDSVVLDVERLGFAQAS-------------------DSNQPPV--------------------
--------------------------------------------------------------------------------
--------------------------------------------NLDQ-LS-------PPHAEAAPRTPADISIAVTS--
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Gasterosteus_aculeatus_RNF130_a
--------------------------------------------------------------------------------
------------------------MSPWWTRSSALLVLILVLTRSVAAAR------------------------SDRNIV
SEEYVGATVNATVMDG------------RGNVLHMMSSDEGTYGQNSPKVDTRGVVITPAQ-HHGVADRQGCDPGTRFLV
PPRNA----------HWVALLQRGN--CTFREKIL-KAAAYNATAVLIYNN---STDKTVKMGHEGTGDTVAVMITEAYG
KEILAHL-ERNLTVVVSVVVGQRGPTKNI---------------------------NRGSLVFVSISFIVLMIISSAWLI
FYFIQK--IRYTSARDRSQ-RRLGDAAKKAIGKLTTRTVKKGDKETDPD------------------------FNHCAVC
IEAYQLNDVVRILPC-KHVFHKVCVDPWLNEHCT----CPMCKLNILKAL------------------------------