>Rattus_norvegicus_(Rat)METTL2A(Chromosome_10:_94522903-94536622)
---------------------------------------------------------------MAASLSEGVPETEDRKR
PQFG---------------------NRFLSDPARVFHHNAWDNVKWSEEQAAAAERKVQENSSQLVCP----EKQ-ADYE
VNAHKYWDDFYKVHENGFFKDRHWLFTEFPELAPSHD--HLVNLHLEKQKNEVSKP-RSSEDGPGLA------AEQHKRP
CTSHGCETRVPPVEEPVTQKLTHLEICADDFPGSSATYRILEVGCGVGNTVFPILQT-NNNP------DLFVYCCDFSAT
AIELVKTN----------------------SEYDPSRCFAFVHDLCDEDQSYPMPKDSLDVIVLIFVLS----AIVPDKM
QKAISKLSRLLKPGGVMLLRDYGRYDMAQLRFKKGQCLSGNFYVRGDGTRVYFFTQDELDTLFTAAGLEKVQN-------
----VVDRRLQVNRGKQLTMYRVWIQCKYSKPLVPSASQHVPTPHTT---------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Rattus_norvegicus_(Rat)METTL6(Chromosome_16:_6924471-6939562)
-------------------------------------------------------------------------------M
T---------------------------SLQRKGPQTR------ILSTGEEEKL--KRDQALVSAF--------KQQKLE
KEAQKNWDLFYKRNSTNFFKDRHWTTREFEELRS----------------------------------------------
-----------------------------CREYEGQKLTLLEAGCGVGNCLFPLLEEDSNIF---------AYACDFSPR
AVDYVKQH----------------------PLYNAERCKVFQCDLTRDDLLDHIPPESVDAVTLIFVLS----AVHPEKM
HLVLLNVYKVLKPGRSVLFRDYGLNDHAMLRFKAGSKLGENFYVRQDGTRSYFFTDEFLAKLFVDAGYEEVVN-------
----EYVFRETVNKKEGLCVPRVFLQSKFRKPPKDPAPTTDSASLLRKEF------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Rattus_norvegicus_(Rat)METTL8(Chromosome_3:_53215967-53310093)
----------------------------------------------------MNVIWRNCICRLRQGKVPHRCQSGVHPV
APLG---------------------SRILTDPTKVFEHNMWDHMQWSKEEEDEARKKVEENSATRVAP----EEQ-VKFE
NAANKYWDTFYQTHKNKFFKNRNWLLREFPEILPVDQNTKEKLGESSWDPARSSIS---------RTQGTETHRQETFVS
--SEPGSRERS-ASNPDLEEYSRGPRKAEQFPGSKATFRILEVPCLGDKTGTPVFNQRRNIP------GSFLYCCDFAPE
AVELVKSH----------------------EAYSEAHCSAFIHDVCDDGLAYPFPDGTLDVILLVFVLS----SIHPDRM
QAVIHRLSRLLKPGGMLLFRDHGRYDNAQLRFKKGRCLSENFYVRGDGTRAYFFTKGEIHRMFCEAGLHEKQN-------
----LVDHRLQVNRKKQIQMHRVWVQGKFQKPSC-WTPRSAD--------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Branchiostoma_floridae_(Amphioxus)METTL2AXP_002606144
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------------MYCCDFSAT
AIDIVKQQ----------------------PDYNTRRCHAFVHDLTDTTSSLPFPPASLDIIIMIFVLS----AIHPDKM
QSTVDHLAKYLKPGGKLLFRDYGRYDLAQLRFKKGRCLSDNFYVRGDGTRVYFFTQDELRTLFGSAGLQEELI-------
----HVDRRLQVNRGRQVKMYRVWLLCKFTKPLD----------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Caenorhabditis_elegans_(Nematode)METTL2A(Chromosome_II:_14969826-14970843)
------------------------------------------------------------MKDEPIMACAEENPDEKPKC
NPFG---------------------TRFLTDDTKVFEHNAWDDVEWSPEQQEEAQRIVQGQKSMKVDE----EKA-MRLL
STPADQWDAFYAHNENRFFKDRNWLLKEFPELNVEDESNLQKE-------------------------------------
------------------------------------KIEILEVGCGVGNTTFPLLQVNNSSS------RLMLHSCDYAPN
AIRVLKSQ----------------------DAYDPEKMNAFVWDITQPASQEAPNVGSLDYIVCIYVLS----AIHPDNI
KNALKNLVRLLKPGGSLLLKDYGRYDLTQLRFKKDRLIDGNLYCRGDGTLVYFFDMEELETLLAEHGLQKKVM-------
----HVDRRLIVNRAKQVKMYRQWIQGKFLKSC-----------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Gallus_gallus_(Chicken)METTL6(Chromosome_2:_41408897-41416546)
------------------------------------------------------------MFHENTSADCLSTLTTSTED
G---------------------------AFQTKGHNTR------ILSPEEAERL--ANDRVLVSDF--------KQLKLE
KEAQKNWDLFYKRNSTNFFKDRHWTTREFQELKA----------------------------------------------
-----------------------------CREFADQKLTILEAGCGVGNCLFPLLEEDLNIF---------AYACDFSPR
AVEYVKKN----------------------SLYSTERCKVFQCDLTKDDLLENIPADSVDVVTLIFVLS----AIHPDKM
HLVLKNIYKVLKPGKCVLFRDYGLYDHAMLRFKSGSKLGENFYVRQDGTRSYFFTTEFLSQLFRAEGYEEVVN-------
----EYVHRETVNRKEDLRVPRVFLQSKFQKPFSKT--------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Pan_troglodytes(Chimpanzee)METTL2A(Chromosome_7:_130011295-130036200)
---------------------------------------------------------------MAGSYPEGAPAVLADKR
QQFG---------------------SRFLSDPARVFHHNAWDNVEWSEEQAAAAERKVQENSIQRVCQ----EKQ-VDYE
INAHKYWNDFYKIHENGFFKDRHWLFTEFPELAPSQNQNHLKDWFLENK-SEVCEC-RNNEDGPGLIM-----EEQHKCS
LKSLEHKTQTPPVEENVTQKISDLEICADEFPGSSATYRILEVGCGVGNTVFPILQT-NNDP------GLFVYCCDFSST
AIELVQTN----------------------SEYDPSRCFAFVHDLCDEEKSYPVPKGSLDIIILIFVLS----AIVPDKM
QKAINRLSRLLKPGGMVLLRDYGRYDMAQLRFKKGQCLSGNFYVRGDGTRVYFFTQEEPDMLFTTAGLEKVQN-------
----LVDRRLQVNRGKQLTMYRVWIQCKYCKPLLSSTS------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Pan_troglodytes(Chimpanzee)METTL6(Chromosome_3:_15646373-15664404)
-------------------------------------------------------------------------------M
A---------------------------SLQRKGLQAR------ILTSEDEEKL--KRDQTLVSDF--------KQQKLE
QEAQKNWDLFYKRNSTNFFKDRHWTTREFEELRS----------------------------------------------
-----------------------------CREFEDQKLTMLEAGCGVGNCLFPLLEEDPNIF---------AYACDFSPR
AIEYVKQN----------------------PLYDTERCKVFQCDLTKDDLLDHVPPESVDVVMLIFVLS----AVHPDKM
HLVLQNIYKVLKPGKSVLFRDYGLYDHAMLRFKAGSKLGENFYVRQDGTRSYFFTDDFLAQLFMDTGYEEVVN-------
----EYVFRETVNKKEGLCVPRVFLQSKFLKPPKNPSPVVLGLDPKS---------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Pan_troglodytes(Chimpanzee)METTL8(Chromosome_2B:_175759018-175871341)
----------------------------------------------------MNMIWRNSISCLRLGKVPRRYQSGYHPV
APLG---------------------SRILTDPAKVFEHNMWDHMQWSKEEEAAARKKVKENSAVRVLL----EEQ-VKYE
REASKYWDTFYKIHKNKFFKDRNWLLREFPEILPVDQKPEEKARESSWDHVKTSATNCFSRMHCPTVPDEKNHYEKSSGS
--SEGQSKTESDFSNLDSEKHKKGPMETGLFPGSNATFRILEVGCGAGNSVFPILNTLQNSP------ESFLYCCDFASG
AVELVKSH----------------------SSYRATQCFAFVHDVCDDGLPYPFPDGILDVILLVFVLS----SIHPDRM
QGVVNRLSKLLKPGGMLLFRDYGRYDKTQLRFKKGHCLSENFYVRGDGTRAYFFTKGEVHSMFCKASLDEKQN-------
----LVDRRLQVNRKKQVKMHRVWIQGKFQKPLH-QTQNSSDMVSTLLSQD-----------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Ciona_intestinalis_(Ascidian)METTL2A(Chromosome_7:_5903036-5903995)
--------------------------------------------------------------------------MDDTKR
PTFG---------------------NRFLKDDAQVFLHNAWDNVEWTEEQESNARQITTAQAENSMPD----EEQ-EKFL
SEAPKFWDKFYEKHENKFFKDRHWLFTEFPELLLVKESKDNEELLCNDDTNDGELL------------------SNNETT
VGS---------------------------FPGSDSKVKFMEIGCGVGNTIFPILKV-NNE-------NLFMYGCDYSQT
AVDIVKNH----------------------KEFNPKSAFVFVHDISTED-EFPIPNESLDVVIMIFVLS----ALQFRKM
GGAVKRIAKLLKPGGVILFRDYGRYDMAQLRFKHRRCISDNFYTRGDGTMVYFFTQGEVKEIFTSAGLMEEQN-------
----LVDRRLQVNRARQIKMYRVWVQAKYRK-------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Ciona_intestinalis_(Ascidian)METTL6(Chromosome_8:_3731993-3734341)
--------------------------------------------------------------------------MEDFES
K----------------------------SQYTSSQVR------SLSDDELQMLENQNKR-LVTEF--------RSQKLE
VEAKKMWDLFYKRNTTNFFKDRHWTSREFGEIEQ----------------------------------------------
------------------------------RIHNNQQTVLLEAGCGVGNAIFPLMAQAKDLF---------VYACDFSPR
AVELVKDN----------------------PSYSETKCKAFQCDLGTDHLSYTIQENSVDLVTLIFVLS----AIHPDKF
EFVLRNIHKVLKPGGYLLFRDYGLNDWAMLRFNNGSKISENFYVRQDGTRAYYFKKEELESLTCASGFDVVSN-------
----EYVMRETINKKKNLKVPRVFLQGKYQKP------------------APT---------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Ciona_savignyi_(Ascidian)METTL2A(reftig_65:_492611-495552)
------------------------------------------------------------------------------ES
-----------------------------SQWTTEEVR------PLTAEEKVMLEKQVSL-LVSDF--------RRDKLE
LEARKMWDLFYKRNSVNFFKDRHWTTREFNEIEE----------------------------------------------
------------------------------RIKSNEHTVLLEAGCGVGNAIFPLMDKYSNLF---------VYACDFSPR
AVQHVKDN----------------------PGFSKKNCNAFQCDISTQSLCDNIQENSVDLVTLIFVLS----AIHPNKF
EFVFENIHKVLKPGGYLLFRDYGLNDWAMLRFSTGSKIAENFYVRQDGTRAYYFKKGELENLASSNGFLVSSN-------
----EYVMRETVNKKKNLKVPRVFLQGKYQK-------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Bos_taurus_(Cow)METTL2A(Chromosome_19:_47512361-47523553)
---------------------------------------------------------------MDCSFPEGDPAAVCGKR
QQFG---------------------SRFLSDPARVFHHNAWDNVEWSEEQAAEAERKVQENSTQRVCQ----EKQ-ADYE
INANKYWNNFYKIHENGFFKDRHWLFTEFPELAPSQN--HLKNLLSENKRSEVYEYYRSGEDGPDLTI-----EEQHRCS
SVSLGDKTQPPLTEESVTQKLHHLEICANEFPGSSATYRILEVGCGVGNTVFPILQT-NNDP------SLFVYCCDFSST
AVELVQTN----------------------SAYDPSRCFAFVHDLCDEDKSYPMPENSLDVIILIFVLS----AIVPDKM
QNAINRLSRLLKPGGIMLLRDYGRYDMAQLRFKKGQCLSENFYVRGDGTRVYFFTQDELDTLFTTAGLEKVQN-------
----LVDRRLQVNRGKQLTMYRVWIQCKYRKPLGSSTG------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Bos_taurus_(Cow)METTL6(Chromosome_1:_154171377-154187728)
-------------------------------------------------------------------------------M
A---------------------------ALQRRGLQTR------ILSSEEEEKL--KRDQALVSDF--------KQQKLE
KEAQKNWDLFYKRNSTNFFKDRHWTTREFEELRS----------------------------------------------
-----------------------------CREFEDQKLTILEAGCGVGNCLFPLLEEDPDIF---------AYACDFSPR
AVEYVKQN----------------------PLYDTERCKVFQCDLTKDDLLEHVPPESVDVVTLIFVLS----AVHPDKM
HLVLQNIYKVLKPGKSVLFRDYGLYDHAMLRFKAGSKLAENFYVRQDGTRSYFFTDEFLARLFLDTGYEEEVN-------
----EYVFRETVNKKEGLCVPRVFLQSKFRKSQKNPIPVTPDLGHES---------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Bos_taurus_(Cow)METTL8(Chromosome_2:_25117252-25154865)
----------------------------------------------------MNVIWRNYISCPRMRKVPHRYQSGCHPV
APLG---------------------SRILTDPTKVFEHNMWDNLEWCTEDLALSRRKVYDNTAIRIIQ----NES-LKYE
SEASKYWDTFYKIHKNKFFKDRNWLLREFPEILPVGQKTEEKVKELSWNHVKINAESFFSKMHCPTMPEEKNHYKESSGS
--SDGQSKAGSDFSKLDSEEYRERPLKTELFPGSNAAFRILEVGCGAGNSVFPILNTLQNVP------EFFLYCCDFASG
AVELVKSH----------------------ASYRAAQCCAFVHDVCDHGLPYPFPDGTLDVILLVFVLS----SIHPDRM
QGVINRLSKLLKPGGMLLFRDYGRYDKTQLRFKRGHCLSENFYVRGDGTRAYFFTKGEVHNMFCKAGLDEKQN-------
----LVDRRLQVNRKKKVKMHRVWVQGKFQKPLH-LTQKSSNLVFSVLSHE-----------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Loxodonta_Africana_(Elephant)METTL2A(SuperContig_scaffold_31:_28391051-28405232)
------------------------------------------------------------------RALKSPLRVPNGKR
EQFG---------------------SRFLSDPARVFHHNAWDNVEWSEEQAAAAEKKVRENSAQRMPQ----EKQ-VDYE
INAHKYWNDFYKIHENGFFKDRHWLFTEFPELAPSQNQNHLKGLLSEDKKSEIPEY-RSSEDGPGLTT-----EEQHKSS
SSSRRDKTQAPSVKN-ITQKLSHLGICADEFPGSSATYRILEVGCGVGNTVFPILQT-NNDP------GLFVYCCDFSST
AVELVQTN----------------------SEYDPSRCLAFVHDLCDEDQSYPMPRDSLDIIILVFVLS----AVAPDKM
QKAVNRLSRLLRPGGMMLLRDYGRYDMAQLRFKKGQCLSENFYVRGDGTRVYFFTQDELDTLFTAAGLEKVQN-------
----LVDHRLQVNRGKQLTMYRVWIQCKYRKPL-----------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Loxodonta_Africana_(Elephant)METTL6(SuperContig_scaffold_103:_683898-701765)
-------------------------------------------------------------------------------M
A---------------------------SLQRKGLQAR------MLSSEEEEKL--KRDQALVSDF--------KQQKLE
KEAQKNWDLFYKRNSTNFFKDRHWTTREFEELRS----------------------------------------------
-----------------------------CREFEDEKLTVLEAGCGVGNCLFPLLEEDLNIF---------AYACDFSPR
AVEYVKQN----------------------PSYNTERCKVFQCDLTKDDLLEHVPSESVDVVMLIFVLS----AIHPDRM
QLVLQNVYKVLKPGKCVLFRDYGLYDHAMLRFKAGSKLGENFYVRQDGTRSYFFTDEFLAQLFTDTGYEEVIN-------
----EYVFRETVNKKEGLCVPRVFLQSKFRKPPKHPAPTSPGPGPESQVL------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Loxodonta_Africana_(Elephant)METTL8(SuperContig_scaffold_3:_55821628-55866082)
----------------------------------------------------MNVIWRNSISCLKIGKAPHRYQSDYRPT
APLG---------------------SRILTDPTKVFEHNMWDHMQWSKEEEEAARKKVEENSAVRVLL----KEQEIHFH
FSALKYRSIFYKIHKNKFFKDRNWLLREFPEILPVDQKTTEKVGELSWDHVKTNTANCFSRMHCPTMPEGKNHYKKNPGS
--SNGRSKAESDFSKPDSEEHRKGPLKTDLFPGSNATFRILEVGCGAGNSVFPILNILQNVP------GSFLYCCDFASG
AVDLVKSH----------------------SSYRAAQCSAFVHDVCDDGLPYPFPDGILDVILLVFVLS----SIHPDSF
S---------------------------------------------------FF--------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Drosophila_melanogaster_(Fruit_fly)METTL2A(Chromosome_3L:_1637942-1639231)
---------------------------------------------MLTTSSSTMLGKYGWQILRRLASKSWEHTRQRKKP
SGAG---------------------SRVLTDAREVFEFNAWDHVQWDEEQELAAKAAVAKNSTSKMEA----EQK-ERFQ
TDAPKFWDSFYGIHDNRFFKDRHWLFTEFPELAPLAADSAVLQ-------------------------------------
------------------------------------PRSIFELGCGVGNTILPLLQY-SSEP------QLKVFGCDFSAR
AIEILRSQ----------------------RQFDEKRCEVFVMDATLDHWQVPFEENSQDIIVMIFVLS----AIEPKKM
QRVLDNCYRYLRPGGLLLFRDYGRYDLAQLRFKSGKCMEDNFYVRGDGTMVYFFTEEELRGMMTQAGLQEEQL-------
----IVDRRLQVNRCRGLKMYRVWIQTKFRKPL-----------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Drosophila_melanogaster_(Fruit_fly)METTL6(Chromosome_2R:_13620760-13621988)
--------------------------------------------------------------------------MEPLEP
------------------------------DVITTQAK------ELSAVERQKLDEQNKRGLVPEY--------KANKLE
IDAQRNWDIFYKRNETRFFKDRHWTTREFQELLD----------------------------------------------
------------------------------QEEFHEKRTLFEVGCGVGNLVFPLLEEQTSEEGCFSNSRFFFYACDFSPR
AVEFVRSN----------------------PLYDPSQISAFQCDITTQQVHDHIPPSSVDICTLIFVLS----AIHPQKF
KDVVQNLGKLLKPGGLLLFRDYGLYDMAQLRFKPGNKIAENLYVRQDGTRSYFFSEEEVSKLFQENGFEVITN-------
----AYVHRRTLNLKEGVDVPRIFLQGKFRR-------------------KNL---------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Takifugu_rubripes_(Fugu)METTL2A(scaffold_15:_1743932-1746233)
-----------------------------------------------MAAPHAAVA--GEAGSGDTELSLASSISEDGKR
PQFG---------------------TRFLTDPRQVFQHNAWDNVEWTEEQEASAKKKVLENC-QPLPS----EKQ-EEYE
NRANEYWNDFYTIHENRFFKDRHWLFTEFPELCPQCSPNNVTHQKVSSTGRCVQDE-----------------ERAKQGA
AVS-PINVN---------------------FPGATASYRILEVGCGVGNTVFPILKT-NNDP------ELFVYCCDFSST
AVDLVKTN----------------------PEYNLGRCFAFVHDLSDVEANYPIPDGTLDVIVLIFVLS----ALHPIKM
QASISRLARLLKPGGVMLLRDYGRYDMAQLRFKKGRCLSDNFYVRGDGTRVYFFTQEELHSMFTEAGLEKVQN-------
----LVDRRLQVNRGKQLTMYRVWIQCKYHKP--LVPS------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Takifugu_rubripes_(Fugu)METTL6a_(scaffold_290:_14351-16248)
------------------------------------------------------------------------KESESISS
V---------------------------LGQDTKATNR------VLTQEEMDKL--DGE-VLVSDF--------KQIKLE
KEAQKNWDLFYKRNSTNFFKDRHWTTREFEELKA----------------------------------------------
-----------------------------CREFASQQLVLLEAGCGVGNCIFPLLDDELNIF---------VYACDFSPR
AVEFVSKN----------------------PLYSPERCCAFQCDLTKDDLRENVPEGSVDVITLIFVLS----AVHPDKM
KLVLQNISRVLKPGGIALFRDYGLHDHAMLRFKSGSKLGENFYVRQDGTRSYFFSK------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Gorilla_gorilla_(Gorilla)METTL6_(Chromosome_3:_15849005-15864866)
-------------------------------------------------------------------------------M
A---------------------------SLQRIGLQAR------ILTSEEEETL--KRDQTLVSDF--------KQQKLE
QEAQKNWDLFYKRNSTNFFKDRHWTTREFEELRS----------------------------------------------
-----------------------------CREFEDQKLTMLEAGCGVGNCLFPLLEEDSNIF---------AYACDFSPR
AIEYVKQN----------------------PLYDTERCKVFQCDLTKDDLLDHVPPESVDVVMLIFVLS----AVHPDKM
HLVLQNIYKVLKPGKSVLFRDYGLYDHAMLRFKAGSKLGENFYVRQDGTRSYFFTDDFLAQLFMDTGYEEVVN-------
----EYVFRETVNKKEGLCVPRVFLQSKFLKPPKNPSPVVLGLDPKS---------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Apis_mellifera_(Honey_bee)METTL2AXP_624474
---------------------------------------------------------------MEEDISKHQQNESNNKR
PQFG---------------------NRILSNNNNVFQHNAWDNIIWDEEQQNLAKQKVNENSTITMSD----EKI-WEYE
HEAYKYWDKFYGIHENKFFKDRHWLFTEFPELAVDIVKQNIKQP---------------------------------LRF
KNENIKK------------NGQETHENILDLPSKNGNK-ILEIGCGVGNTVFPILLY-NTDA------NLFVYCCDFSAK
ALDILKQN----------------------SAYDTSRCKAFILDVTQEEWETPFEPESLDIIVLIFVLS----AINPEKM
KHIIEQIHKYLKSGGLVLFRDYGRYDLAQLRFKKGSCLANNFYVRGDGTRVYFFTQEEIRILFTSCGFIEEQN-------
----LIDRRLQINRGKQLKMYRVWIQGKYRK-------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Apis_mellifera_(Honey_bee)METTL6XP_623532
-------------------------------------------------------------------------MAESMKS
------------------------------EYASHVAK------QLTEEEIVKMRAQNSR-LVSEF--------RANQLE
KDAKKHWDLFYKRNDTRFFKDRHWTTREFDELLN----------------------------------------------
------------------------------LNTKNEQNVLFEVGCGVGNFVYPLIEDGLKFK--------MIFACDLSSR
AVELTKNH----------------------SLYDPENMKIFQTDITTENCFLEVN-YPVNIATLIFVLS----AIHPKKF
RKVVENLYNVLDKGGIVLFRDYGLYDMAQLRFKPGHKISENLYMRQDGTRTYYFSEKEVSNLFRSVGFEVLTC-------
----HYVQRRTVNFKEKIDVPRIFVQGKFVKPPRHPRPPPLPPLDDSMLGRNTFGCEGGGALVPTRGDSPSPRPFFHHVR
GDLYIKALFWVAKASETTISLTYPVPYLTDKQLAYRNNTLFRINMRSLVILVLVAVAISRVSCRELKGDKRSSRLPLKGK
RGIVDYSGGSSYNSPLISSGYTGGYSSAHSPSIPSIQSLGGGTMGYSLGSGGLGHNFGISLGGQHFGGAQSYSSPGLGSL
AGGGGLFSPPSKNGPVTFGIHGGGGSSSSTSYSAPVYATGVHGLSSYGSGSSHQGISLSSMLGSGHSYGLPASSLGSGHA
LSMIHSISPGYAASGGLVIDSSSLGKGSSSYSLPLSSSHGSSSLSTGSSSSYALPVSSGSSHSGISALHSGSTASYSLPV
SSGSSIGGHISFSGGSSADSYSLPASSISASHPYVTVMSDASSSSSGSSSYSSPSSSYSAPASGSISSYSSPASSYSSSG
YSGTSSSYSPIYSAPSTSYGTPMESHGSYSNLAARYVEYPGSKSYEDSTSSNKYDTISYSSPSGKY
>Hydra_magnipapillata_(Hydra)METTL2AXP_002156347
------------------------------------------------------------------------MIFENEVY
G---------------------------FST-------KDDQILSEVELKKLAC--DRN--LVSNY--------KQIQLE
INAQKNWDLFYKRNSTKFFKDRHWTTREFDEITS----------------------------------------------
-----------------------------EKLNDKK---LLEVGCGCGNAIFPLIEENKNIF---------VYACDFSSR
AIEYVKAH----------------------KLYELSRCLAFQSDVTKDNLCSFVPEASIDIALMIFVLS----AVHPDKM
KEVLQNVHRVLKPGGIVLFRDYGLYDHAMLRFGPGHKLDDRFYVRQDGTRAYYFSTDKLFELFTSCGYEVVEN-------
----TYIHRRTINKKEGIDVPRIFVQGKFTKLS-----------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Hydra_magnipapillata_(Hydra)METTL8XP_00216525
----------------------------MDIVTTGVANGKSKQRVVLGESVSSWVDIVSGVPQGSVLGPILFLIYINDLL
S---------------------------QLTNQLLLYADDCKVIALSRLSKMQT--VNCPAIEEGYSDSSGVADKQIQLE
INAQKNWDLFYKRNSTKFFKDRHWTTREFDEITS----------------------------------------------
-----------------------------QKLNDKK---LLEVGCGCGNAIFPLIEENKNIF---------VYACDFSSR
AIEYVKAH----------------------KLYELSRCLAFQSDVTKDNLCSFVPEASIDIALMIFVLS----AVHPGKM
KEVLQNVHRVLKPGGIVLFRDYGLYDHAMLRFGPGHKLDDRFYVRQDGTRAYYFSTDKLFELFTSCGYEVVEN-------
----TYIHRRTINKKEGIDVPRIFVQGKFTKLS-----------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Anolis_carolinensis_(Lizard)METTL6(Chromosome_6:_36445680-36453110)
-------------------------------------------------------------------------------S
G---------------------------GFPKRGHKMR------TLSPEEAERL--AKDPVVVSDF--------KQQKLE
KEAQRNWDLFYKRNSTNFFKDRHWTTREFEELKA----------------------------------------------
-----------------------------CREFDDQKLTILEAGCGVGNCLFPLLEEDLNIF---------AYACDFSPR
AVEYVKQN----------------------PLYDPQRCKVFQCDLTKDDLLENVPPDSVDVATLIFVLS----AIHPEKM
HLVLCNIYKVLKPGKCVLFRDYGLYDHAMLRFKSANKLGENFYVRQDGTRSYFFSDDFLAELFLSAGYKQVVN-------
----EYVLRETVNKKEGLCVPRVFLQSKFQKPHKE---------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Macaca_mulatta_(Macaque)(Chromosome_16:_57929156-57956471)
---------------------------------------------------------------MAGSYPEGAPAVLADKR
QQFG---------------------NRFLSDPARVFHHNAWDNVEWSEEQAAAAERKVQENSTQRVCQ----EKQ-VDYE
INAHKYWNNFYKIHENGFFKDRHWLFTEFPELAPSQNQNHLKDWFLENKRSEVPEC-RNNEDGPSLIM-----EEQHKCS
SKSLEHKTETPPVEENVTQKISDLEICADEFPGSSATYRILEVGCGVGNTVFPILQT-NNDP------GLFVYCCDFSST
AIELVQTN----------------------PEYDPSRCFAFVHDLCDEEKSYPVPKGSLDIIILIFVLS----AIVPDKM
QKAINRLSRLLKPGGMMLLRDYGRYDMAQLRFKKGQCLSGNFYVRGDGTRVYFFTQEELDMLFTTAGLEKVQN-------
----LVDRRLQVNRGKQLTMYRVWIQCKYCKPLLSSTS------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Macaca_mulatta_(Macaque)METTL6(Chromosome_2:_157739948-157757392)
-------------------------------------------------------------------------------M
T---------------------------SLPRKRLQAR------VLSSEEEEKL--KRDQTLVSDF--------KQHKLE
QEAQKNWDLFYKRNSTNFFKDRHWTTREFEELRS----------------------------------------------
-----------------------------CREFEDQKLTILEAGCGVGNCLFPLLEEDPNIF---------AYACDFSPR
AVEYVKQN----------------------PLYDTERCKVFQCDLTKDDLLDHVPPGSVDVVMLIFVLS----AVHPEKM
HLVLENIYKVLKPGKSVLFRDYGLYDHAMLRFKAGSKLGENFYVRQDGTRSYFFTDEFLAQLFMDTGYEEVVN-------
----EYVFRETVNKKEGL--------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Macaca_mulatta_(Macaque)METTL8(Chromosome_12:_35007353-35016039)
--------------------------------------------------------------------------------
----------------------------------------------------------------------------VKYE
REASKYWDTFYKIHKNKFFKDRNWLLREFPEILPVDQKPEEKARESSWDLVNTSATNCFSRMHCPTMPEEKNHYEKSSGS
--SEGQSKTESDFSNLD-----------GLFPGSNATFRILEVGCGAGNSVFPILNTLQNSP------ESFLYCCDFASG
AGELIKSH----------------------SSYRAAQCFAFVHDVCDDGLPYPFPDGILDVILLVFVLS----SIHPDR-
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Oryzias_latipes_(Medaka)METTL2A(Chromosome_8:_5685381-5687945)
-----------------------------------------------MEAPCAVDA--VAAGSSETGHSLSGSSSAESRR
PQFG---------------------TRFLTDPKQVFQHNAWDNVEWTDEQEEAAKRKVSENS-YPLPA----EKQ-EEYD
SRANEYWNEFYTIHENRFFKDRHWLFTEFPELAPQCSVLNHTS-HIDEPQGSNLDQ-----------------NRCRDSG
AED---SRD---------------------FPGSSASYRILEVGCGVGNTVFPILKT-NNDP------GLFVYCCDFSST
AVELVKNN----------------------PEYDPGRCFAFVQDLSDADASYPIPDGSLDVIVLIFVLS----ALHPDKM
QASIRRLARLLKPGGMILLRDYGRYDMAQLRFKKGRCLSENFYVRGDGTRVYFFTQDELHELFTRAELEKVQN-------
----LVDRRLQVNRGKQLTMYRVWIQCKYKKAS-----------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Oryzias_latipes_(Medaka)METTL6(Chromosome_16:_23610188-23614347)
----------------------------------------------------------------MNRAEDTESTDDTPTC
L---------------------------SGQTKTSSSR------DLTQEEQGRF--KTERVLVSEF--------KQIKLE
KEARKNWDLFYKRNATNFFKDRHWTTREFEELKE----------------------------------------------
-----------------------------CREFESQKLVLLEAGCGVGNCLFPLLEDDLNIF---------VYACDFSPR
AVEFVKQN----------------------PLYCPERCCAFQCDLTKDDLTGNVPEGSVDVVTLIFVLS----AVHPEKM
KLALENINKVLKPGGVVLFRDYGLHDHAMLRFKAGSKLGENFYVRQDGTRSYFFSKEHLAQLFKEAGFVSVVN-------
----DYVLRETVNKKEGLCVQRVFLQSKFTKAALPQVSCSPVFPGSGK--------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Oryzias_latipes_(Medaka)METTL8(Chromosome_21:_23977170-23980133)
---------------------------------------------------------------LAPSFAVKFKNTKPRPV
APLG---------------------SRILTNTDDIFKHNMWDHIKWTVEDKENARQKVQENSSVQIPA----PER-GKFD
AEACQFWDKFYEVHQSKFFKDRRWLFLEFPELLHPSHRENRVTN-VHHEHKVIQIQSGCT-------ADTEKRHYQHNDP
TGGSWKIN------NWNYQEAQQELKDVPSFLGHDASFRILEVGCGVGNSVFPILNNIRNT-------DSFLYCCDFSAR
AIQMVQDH----------------------QDYDKSICHAFVHDICEEGSSFPFPPQSLDVILAVFVLS----SIHPERL
QGVVNRLSSYLKPGGMFLFRDYGRYDFSQLRFKKGRCLSDHFYTRGDGTCVYYFTEEEVGDLFSKAGLEEIQN-------
----LEDRRLQVNRKKKVAMRRVWIQSKFRKPSLHFLPEHSP--------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Anopheles_gambiae_(Mosquito)METTL2AXP_316017
---------------------------------------------MTETTEETIP---------------TDQSEQPSVR
PQFG---------------------NRFLSAGDDVFQHNAWDNVQWDEEQENAALEGVKKNSSVKLSD----AEV-TRLE
TEADQNWDRFYGIHQNRFFKDRHWLFTEFPELAPAKGPNTVPERVLPDGE------------------------------
-------------------PVKRAEEVSQESDGQQRSRTIFEIGCGVGNTVFPILKY-SEEK------NLMIYASDFSRQ
AIDIMCQS----------------------PEYDTNRCKAFVLDATADRWDVPFAENSIDIVVLIFVLS----AIDPERM
QHVVNQIARYLKPGGMVMLRDYGRYDLAQLRFKPGKCLKDNFYVRGDGTLVYFFTQEDLRTLFTSAGLVEEQN-------
----IVDRRLQVNRGKMVKMYRVWVQVKFRKPTDN---------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Anopheles_gambiae_(Mosquito)METTL6XP_318925
------------------------------------------------QVELTSHPRLAYRHTQFSKGFSTPKQSLSFKS
EPSFCRYEKSKQPRSLAKGTNGTQKAFNLGDVVTDAAK------ILTEEERTKLEEQNKR-LVTPF--------QALKLE
QEARKHWDLFYKRNENRFFKDRHWTTREFSELLAGED-------------------------------------------
---------------PAAAASSSPLAKPDNVERISVEKKLLEIGCGVGNLIFPLIEDGHRDY--------FIYACDLSPR
AVELVQKH----------------------NLYDERYMKAFACDITTEEVFQTLPEASLDIVTLIFVLS----AIHPEKF
QSTVANIYRLLKPGGVVLFRDYGLYDMAQLRFKPGHKIAENFYMRQDGTRSYYFAEEEVSKLFCQTGFTVMVN-------
----SYIHRRTVNPKENIDVPRIFVQGKFLKP------------------EQT---------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Mus_musculus_(Mouse)METTL2A(Chromosome_11:_105126425-105140394)
---------------------------------------------------------------MAASFPEGVPETEDGKR
PQFG---------------------HRFLSDPARVFHHNAWDNVKWSEEQAAAAERKVQENSSPLVCP----EKQ-VDYE
VNAHKYWDDFYRIHENGFFKDRHWLFTEFPELAPSHS--HLTGVPLEKQRSDVC------EDGPGLT------AEQHKCS
CASPGCETQVPPLEEPVTQKLGHLEISGEEFPGSSATYRILEVGCGVGNTVFPILQT-NNNP------NLFVYCCDFSAT
AIELLKTN----------------------SQYDPSRCYAFVHDLCDEDQSYPVPEDSLDVIVLIFVLS----AIVPDKM
QKAISKLSRLLKPGGVMLLRDYGRYDMAQLRFKKGQCLSGNFYVRGDGTRVYFFTQGELDTLFTAAGLEKVQN-------
----LVDRRLQVNRGKQLTMYRVWIQCKYSKPLALRSSQHVPIPHATESSSHSGLL------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Mus_musculus_(Mouse)METTL6(Chromosome_14:_31478320-31495030)
-------------------------------------------------------------------------------M
A---------------------------SFQRKGLQAR------ILSTEEEEKL--KRDQALVSAF--------KQQKLE
KEAQKNWDLFYKRNSTNFFKDRHWTTREFEELRS----------------------------------------------
-----------------------------CREYEGQKLTLLEAGCGVGNCLFPLLEEDLNLF---------AYACDFSPR
AVDYVKQH----------------------PLYNAERCKVFQCDLTRDDLLDHVPPESVDAVTLIFVLS----AVHPEKM
RLVLLNVYKVLKPGRSVLFRDYGLNDHAMLRFKAGSKLGENFYVRQDGTRSYFFTDEFLAQLFVDAGYEEVVN-------
----EYVFRETVNKKEGLCVPRVFLQSKFRKPPKDPAPTSDSASL-----------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Mus_musculus_(Mouse)METTL8(Chromosome_2:_70964561-71055583)
----------------------------------------------------MNVIWRSCICRLRQGKVPHRCQSGVHPV
APLG---------------------SRILTDPAKVFEHNMWDHMQWSKEEEDAARKKVEENSATRVAP----EEQ-VKFE
SDANKYWDIFYQTHKNKFFKNRNWLLREFPEILPVNQNTKEKVGESSWDQVGSSIS---------RTQGTETHCQESFVS
--PEPGSRGRS-APDPDLEEYSKGPGKTEPFPGSNATFRILEVGCGAGNSVFPILNTLQNIP------GSFLYCCDFASE
AVELVKSH----------------------ESYSEAQCSAFIHDVCDDGLAYPFPDGILDVVLLVFVLS----SIHPDRM
QAVAHRLSRLLKPGGMLLFRDHGRYDNAQLRFKKGRCLSENFYVRGDGTRAYFFTKGEIRRMFCEAGLHEKQN-------
----LVDHRLQVNRKKQVQMHRVWIQGKFQKPSP-WTPQSGN--------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Nematostella_vectensis_(Sea_anemone)METTL2AXP_001637965
-------------------------------------------------------------------------MAEGKDI
R---------------------------DIQNETESSIQGLYPRVLTDEEKQKL--ERDTSCISEF--------KRNKLE
QDARKNWDLFYKRNSTNFFKDRRWTTREFTELLN----------------------------------------------
-----------------------------VEDEKLNEKVLLEAGCGVGNLINPLLEEGYNFY---------FHACDFSPR
AVNFVKES----------------------PFYDEAKVNAFQCDLTKDDLLENIPACSVDIATLIFVLS----AIHPDKM
ITALLNIFKVLKPGGLLLLRDYGLYDHAMLRFAPGHKLSEQFYVRQDGTRAFYFSQDDLEVLFKKAGFVVLMN-------
----KYVEKRTVNKKENIDVPRIFVQGKFMKPES----------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Monodelphis_domestica_(Opossum)METTL2A(Chromosome_2:_208905141-208932130)
---------------------------------------------------------------MADSCPESVSATTRDKR
VQFG---------------------NRFLNDPARVFQHNAWDNVEWSEEQEAEAERRVRENSAQRVPP----EKQ-VDYE
VNAHKYWNNFYKIHENGFFKDRHWLFTEFPELTPNQNKSNLKNLLLKDGDFEIIEH-RNSGNGLGLIVSNT--QEQHKAS
SHSVDDKEQKHPIEE-TTQNTCHLDINTDGFPGSSATYRILEVGCGVGNTVFPILHT-NNDP------GLFVYCCDFSTT
AVDLVQTN----------------------SEYDPSRCFAFVHDLCDEEKSYPMPRESLDVIILIFVLS----SIVPDKM
QNAITRLSYLLKPGGMILLRDYGRYDMAQLRFKTGRCLSENFYVRGDGTRVYFFTQDELDTLFTTAGLEKVQN-------
----MVDHRLQVNRGKQLTMYRVWIQCKYRKPFSPNIS------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Monodelphis_domestica_(Opossum)METTL8(Chromosome_4:_181416514-181490560)
----------------------------------------------------MNAIQRLWASSLRKRRMWVRFQSNDRPA
VPLG---------------------SRILADPAKVYEHNMWDHMEWSQEEEEAAREKTTENSSVRVQL----EDQ-VKYE
NQASKYWNNFYEIHKNKFFKDRNWLLREFPEILPVGLQTKEEKEKMSWDCVKTDPTDSFLKTDCLAVPKRIESYKNDFGD
NFTYSQSKIRS-SDSQHPNKKKEEAAKTKLFPGSCATFRILEVGCGAGNSVFPILNALKNAP------ETFLYCCDFASE
AVELVKSH----------------------SSYSPAQCSAFVHDVCDDGLSYPFPDGILDVILLVFVLS----SIHPDRM
QGVVNRLSKLLKPGGMLLFRDHGRYDFTQLRFKKGYCLSENFYVRGDGTRAYFFTKGEVHNMFHQAGLDEKQN-------
----LVDRRLQVNRKKKVKMYRVWVQGKFQKPLHSFHHNHSDNCIPGISAG-----------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Strongylocentrotus_purpuratus_(Sea_urchin)METTL2AXP_780030
MILGCHFLKHGLALGSKIIRHRKGFSTSVHAYQVRGDENLHVKELLEERNHQYPSSDSGKIMSAGEELPVTKDDAASVKR
PQFG---------------------NRFLENPDNVFQHNAWDNVAWDPEQLEAAKKKVGENSSQQVET----EKK-ELYE
ADADRYWNEFYSLHQHKFFKDRHWLFTEFPELSSDNAQASAKECSSERGASQETSE-PRTMDSLTTGGSNT--SAEATER
KNEDCEHGPTSSRTSRSESGTDEIHAASDDFPGKSAHKRILEVGCGVGNTIFPILQT-NADP------GLFVYGCDFSSV
AVDIVRQH----------------------AEYNPSRCHAFVCDVSDPAASFPVPDNSLDLVVLIFVMS----AINPDRF
LSTIQTLTRLLKPGGRILFRDYGRYDLAQLRFKKGRCLSENFYVRGDGTRVYFFTQDELRELFISAGLVEEQN-------
----TIDKRLQVNRGRQLTMYRVWIQCKYRKP------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Strongylocentrotus_purpuratus_(Sea_urchin)METTL6XP_794407
-------------------------------------------------------------------------MEKEKDG
G---------------------------GWVTTKQ-------PRDLTEAEKQKL--AEDETCVSDF--------KQNKLE
LEAKKNWDLFYKRNSTNFFKDRHWTTREFEELI-----------------------------------------------
-----------------------------AESREGKQKSLLEVGCGVGNTVYPLLDASPEIF---------IHCCDFSPR
AVQFVKEH----------------------SAYDPARVNAFQCDITCDDLTNNIAASSVDMVTMFFVLS----AIHPDKM
LQSIQNIYKALCPGGLVLFRDYGLHDHAMLRFSKGHKLSENFYVRQDGTRAFYFSTDVLSDLFIKAGFDVVVN-------
----EYVYRETVNKKEGLSVPRVFVQSKFSKKIAENS-------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Gasterosteus_aculeatus_(Stickleback)METTL6(scaffold_122:_13517-15684)
-------------------------------------------------MALSQRGRFPGESEASHPKEDVGSNGELPPR
L---------------------------PGRNQSSTAES-----VPPRGERDGL--GGSAAPASGF--------RLRKLE
EEAQKNWDLFYKRNTTNFFKDRHWTTREFQELQA----------------------------------------------
-----------------------------CRELEAQRLVLLEAGCGVGNCLFPLLEDDRDVF---------VYACDFSPR
AVDLVKKN----------------------PLYTPERCCAFQCDLTKDDLRTQVPEGGVDVVTLIFVLS----AVHPDKM
QLVLQNISRVLKPGGVVLFRDYGLNDHAMLRFKARSKLGENFYVRQDGTRSYFFSKELLAELFAGAGLQSVSN-------
----DYVLRETVNKKEGLCVPRVFLQSKFTKPGQSQGC------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Gasterosteus_aculeatus_(Stickleback)METTL8(groupXVI:_10271231-10276592)
----------------------------------------------------MHQLQSFSVAKVLSRLSSRLHSTRGRPS
APLG---------------------SRILTKNDDIFKHNMWDHVQWTEEEKENARQKAKENSSTQIPL----KEQ-GTFD
TEACQYWDKFYQMHQERFFKDRKWLFLEFPELLPYGAKGQNANGRLGDQQASHPRPTGSSP------TDTETRLQQPNGP
THHHRNTT--PPDHQGAAPEKNKAPKQTPTFPGQQSSFRILEVGCGVGNSVFPILSSIKET-------DAYLYCCDFSPC
AIQLVKDH----------------------PDYSDSMCHAFVHDICEE-ASFPFPPKSLDVILAVFVLS----SIHPERT
QGIVKRLSTYLKHGGIFLFRDYGRYDFSQLRFKKGRCLSENFYTRGDGTCVYFFTKGEVHDLFSSAGLEEIQN-------
----LEDRRLQVNRGKKVAMHRVWMQSKYRKL------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Tetraodon_nigroviridis_(Tetraodon)METTL2A(Chromosome_3:_13418764-13421503)
-----------------------------------------------MAAPDAVAG--VEAGGGDTDLALASSITEDGKR
PQFG---------------------TRFLTDPRQVFQHNAWDNVEWTEEQEASAKKKVLENS-QPLPS----EKQ-EEYE
NRANEYWNEFYTIHENRFFKDRHWLFTEFPELCPQWN-SSVNDQEVSSTGAGFLDE-----------------EQTKKIT
AVPHIINAH---------------------FPGATASYRILEVGCGVGNTVFPILKT-NNDP------DLFVYCCDFSST
AVDLVKTN----------------------PEYDPGRCFAFVHDLGDVEADYPVPNGTLDVIVLIFVLS----ALHPNKM
QASISRLSQLLKPGGVMLLRDYGRYDMAQLRFKKGRCLSDNFYVRGDGTRVYFFTQDELHSIFTGAGLEKVQN-------
----LVDRRLQVNRGKQLTMYRVWIQCKYRKPPAAIPDAVEGGTEHNHN-------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Tetraodon_nigroviridis_(Tetraodon)METTL6(Chromosome_Un_random:_34558737-34560227)
-------------------------------------------------------------------------------M
C---------------------------RFEKQSIRNR------VLTQEEMDKL--GAE-VLVSDF--------KQIKLE
EEAQKNWDLFYKRNTTNFFKDRHWTTREFEELKA----------------------------------------------
-----------------------------CREFAAQRLVLLEAGCGVGNCIFPLLEDDLTLF---------VYACDFSPR
AVEFVKKH----------------------PLYCPERCCAFQCDLTKDDLRQHVPEGSVDVITLIFVLS----AVHPDKM
TLVLQNISRVLKPGGILLFRDYGLHDHAMLRFKAGSKLGENFYVRQDGTRSYFFSKDFLAKLVEEAGLQPVAN-------
----DYVLRETVNKKEGLCVPRVFLQSKFTKPSQSRSL------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Taeniopygia_guttata_(Zebra_finch)METTL6(Chromosome_2:_61884839-61892030)
--------------------------------------------------------------------------------
G---------------------------AFQKKGHSAR------VLSPEEAEKL--AKDQVLVSDF--------KQLKLE
KEAQKNWDLFYKRNSTNFFKDRHWTTREFQELKA----------------------------------------------
-----------------------------CREFADQKLTILEAGCGVGNCLFPLLEEDMNIF---------AYACDFSPR
AVDYVKKN----------------------ALYNTERCKVFQCDLTKDDLLDNIPADSVDVVTLIFVLS----AIHPDKM
HLVLRNIYKVLKPGKCVLFRDYGLYDHAMLRFKSGSKLGENFYVRQDGTRSYFFTEEFLSQLFKAEGYEQVVN-------
----EYVQRETVNRKEDLHVPRVFLQSKFQKP------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Danio_rerio_(Zebrafish)METTL2A(Chromosome_3:_19552544-19570044)
-----------------------------------------------MAAPAVAADSPVIENMPETAGGATENSAEAQKR
PQFG---------------------TRFLTDPRQVFQHNAWDNVEWSAEQEEAALKKVQENS-QPLPA----EKQ-EEFD
DRANEYWNDFYTIHENRFFKDRHWLFTEFPELAPQQK--HLRGAEEKESLEHMLNG-----------------EDVSSN-
------HTHDE-------------------FPGASASYRILEVGCGVGNTVFPILKT-NNDP------GLFVYCCDFSST
AVDLVKSN----------------------PEYDPSRCHAFVHDMSDESGEYPMPDHSLDVIVLIFVLS----ALHPEKM
QKSINRLGRLLKPGGVLLLRDYGRYDMAQLRFKKGRCLSENFYVRGDGTRVYFFTQDELHDLFSSAGLEKLQN-------
----LVDRRLQVNRGKQLTMYRVWVQCKYRKVLAPT--------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Homo_sapiens_(Human)METTL2A(Chromosome_17:_60501228-60527454)
---------------------------------------------------------------MAGSYPEGAPAVLADKR
QQFG---------------------SRFLRDPARVFHHNAWDNVEWSEEQAAAAERKVQENSIQRVCQ----EKQ-VDYE
INAHKYWNDFYKIHENGFFKDRHWLFTEFPELAPSQNQNHLKDWFLENK-SEVPEC-RNNEDGPGLIM-----EEQHKCS
SKSLEHKTQTLPVEENVTQKISDLEICADEFPGSSATYRILEVGCGVGNTVFPILQT-NNDP------GLFVYCCDFSST
AIELVQTN----------------------SEYDPSRCFAFVHDLCDEEKSYPVPKGSLDIIILIFVLS----AIVPDKM
QKAINRLSRLLKPGGMMLLRDYGRYDMAQLRFKKGQCLSGNFYVRGDGTRVYFFTQEELDTLFTTAGLEKVQN-------
----LVDRRLQVNRGKQLTMYRVWIQCKYCKPLLSSTS------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Homo_sapiens_(Human)METTL2B(Chromosome_7:_128116783-128142978)
---------------------------------------------------------------MAGSYPEGAPAILADKR
QQFG---------------------SRFLSDPARVFHHNAWDNVEWSEEQAAAAERKVQENSIQRVCQ----EKQ-VDYE
INAHKYWNDFYKIHENGFFKDRHWLFTEFPELAPSQNQNHLKDWFLENK-SEVCEC-RNNEDGPGLIM-----EEQHKCS
SKSLEHKTQTPPVEENVTQKISDLEICADEFPGSSATYRILEVGCGVGNTVFPILQT-NNDP------GLFVYCCDFSST
AIELVQTN----------------------SEYDPSRCFAFVHDLCDEEKSYPVPKGSLDIIILIFVLS----AVVPDKM
QKAINRLSRLLKPGGMVLLRDYGRYDMAQLRFKKGQCLSGNFYVRGDGTRVYFFTQEELDTLFTTAGLEKVQN-------
----LVDRRLQVNRGKQLTMYRVWIQCKYCKPLLSSTS------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Homo_sapiens_(Human)METTL6(Chromosome_3:_15452524-15469025)
-------------------------------------------------------------------------------M
A---------------------------SLQRKGLQAR------ILTSEEEEKL--KRDQTLVSDF--------KQQKLE
QEAQKNWDLFYKRNSTNFFKDRHWTTREFEELRS----------------------------------------------
-----------------------------CREFEDQKLTMLEAGCGVGNCLFPLLEEDPNIF---------AYACDFSPR
AIEYVKQN----------------------PLYDTERCKVFQCDLTKDDLLDHVPPESVDVVMLIFVLS----AVHPDKM
HLVLQNIYKVLKPGKSVLFRDYGLYDHAMLRFKASSKLGENFYVRQDGTRSYFFTDDFLAQLFMDTGYEEVVN-------
----EYVFRETVNKKEGLCVPRVFLQSKFLKPPKNPSPVVLGLDPKS---------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Homo_sapiens_(Human)METTL8(Chromosome_2:_172180297-172290596)
----------------------------------------------------MNMIWRNSISCLRLGKVPHRYQSGYHPV
APLG---------------------SRILTDPAKVFEHNMWDHMQWSKEEEAAARKKVKENSAVRVLL----EEQ-VKYE
REASKYWDTFYKIHKNKFFKDRNWLLREFPEILPVDQKPEEKARESSWDHVKTSATNRFSRMHCPTVPDEKNHYEKSSGS
--SEGQSKTESDFSNLDSEKHKKGPMETGLFPGSNATFRILEVGCGAGNSVFPILNTLENSP------ESFLYCCDFASG
AVELVKSH----------------------SSYRATQCFAFVHDVCDDGLPYPFPDGILDVILLVFVLS----SIHPDRM
QGVVNRLSKLLKPGGMLLFRDYGRYDKTQLRFKKGHCLSENFYVRGDGTRAYFFTKGEVHSMFCKASLDEKQN-------
----LVDRRLQVNRKKQVKMH-----------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Danio_rerio_(Zebrafish)METTL8(Chromosome_9:_3515641-3531474)
------------------------------------------------------MRGLVKLTARAVSFIPCRQCGGGRPP
APLG---------------------GRILSNPDDVFKHNMWDHVQWTEEEREKARQKAEENSEEKIPV----EEQ-SKYD
REAHKYWDQFYEMHQNKFFRNRNWLFTEFPELLP-------------------PDTGGMLM------AEQEQGLESVNRE
KHDYKDTY-----------------------PGHHAAFRILEVGCGAGNSVFPIINTIRGS-------KAFLYCCDFSSR
AIELIQKH----------------------PDYDPAVCHAFVRDICDATSPFPFPPESLDIILVVFVLS----AIHPARA
QAVVRGLAGLLKQGGMVLFRDYGRYDLSQLRFKKGQCLSENFYSRQDGTCVYFFTKDEVHGLFSAAGLEELQN-------
----LEDRRLQVNRGKKILMHRVWMQSKYRKPEK----------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Takifugu_rubripes_(Fugu)METTL6b(scaffold_8140:_2753-3864)
-------------------------------------------------------------------------------S
V---------------------------LGQDTKATNR------VLTQEEMDKL--DGE-VLVSDF--------KQIKLE
KEAQKNWDLFYKRNSTNFFKDRHWTTREFEELKA----------------------------------------------
-----------------------------CREFASQQLVLLEAGCGVGNCIFPLLDDELNIF---------VYACDFSPR
AVEFVKKN----------------------PLYSPERCCAFQCDLTKDDLRENVPEGSVDVITLIFVLS----AVH-DKM
KLVLQNISRVRT------FKN------VIVSFICKAQ-------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Tetraodon_nigroviridis_(Tetraodon)METTL8b(Chromosome_2:_13809251-13811901)
---------------------------------------------------------------LCSTITTRFKGTDGRPS
APLG---------------------SRILTSPDDVFNHNMWDHIQWTEEDIENARQKAEENSSVQIPL----HEQ-RKFD
FQAREFWDKFYTMHQDKFFKDRKWLLFEFPELLPSGATN-------------MPHASGAS-------TDTENQQRHHNSP
AHHQKQTSGDPSSCQGADAEKDEDSRR--TFPGQHASFRILEVGCGVGNSLFPIIHSIRET-------NAFLFCCDFSPC
AIRLLKAN----------------------PEYDECVCHAFVHDICEETACLPFPPQSLDAILAVFVLS----AIHPDRL
QGVVNRLSSYLKHGGIFLFRDYGRYDFSQLRFKKGQCLSENFYTRGDGTCVYFFTKGETHHLFTNAGLEEVQN-------
----LQDRRLQVNRGKKVAMLRVWTQSKYRKP------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------
>Gasterosteus_aculeatus_(Stickleback)METTL2A_(groupXI:_6226291-6229551)
--------------------------------------------------------------------------------
----------------------------LTDPRQVFQHNAWDNVEWSEEQEASAKRKVSENN-QPLPQ----EKQ-EEYD
SRANEFWNGFYTIHENRFFKDRHWLFTEFPELAPQCSLDNESHLEVSDSDHSQQER-----------------LQREHRS
EVPSLSHTDGD-------------------IPGSLATYRILEVGCGVGNTVFPILKT-NNDS------GLFVYCCDFSST
AVELVKTN----------------------PEYDPGRCFAFVHDLSDVEADYPVPEGTLDVIVLIFVLS----ALHPDKM
QASISRLARLLKPGGVMLLRDYGRYDMAQLRFKKGRCLSENFYVRGDGTRVYFFTQDEVHEMFTEAGLEKMQN-------
----LVDRRLQVNRGKQLTMYRVWIQCKYRKAP-AQPLGSDGQVRGKDPPSSTIA-------------------------
-------------------------------------------------------------------