>Homo_sapiens-PLEKHA3(ENSP_234453)
-----------------------------------------------------------------------MEGVLYKWT
NYLTG---------------------------WQPRWFVLDNGILSYYD-------------------------------
----------SQDDVCKGSKGSIKMAVCEIK--VHSADNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTR
TKKEKEIS-----------------ETSESLKTKMSELRLYCDLLMQQVHTIQ-EFVHH---------------DENHSS
PSAENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMF-QLHHPDPLVSPVS------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------PSPVQM--MKRSVSHPGS
CSSERSSHSIKEPVSTLH------------------------------------------------------RL-----S
QRRRRTYSDTDSCS--------------------DIPLEDPDRPVHCSKNTLNGDLAS----------------------
--------------------------------------------------ATIPEESRLMA--------KKQSESEDTLP
SFSS-----------------------------------------------------------
>Pan_troglodytes-PLEKHA3(ENSPTRP_21689)
-----------------------------------------------------------------------MEGVLYKWT
NYLTG---------------------------WQPRWFVLDNGILSYYD-------------------------------
----------SQDDVCKGSKGSIKMAVCEIK--VHSADNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTR
TKKEKEIS-----------------ETSESLKTKMSELRLYCDLLMQQVHTIQ-EFVHH---------------DENHSS
PSAENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMF-QLHHPDPLVSPVS------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------PSPVQM--MKRSVSHPGS
CSSERSSHSIKEPVSTLH------------------------------------------------------RL-----S
QRRRRTYSDTDSCS--------------------DIPLEDPDRPVHCSKNTLNGDLAS----------------------
--------------------------------------------------ATIPEESRLMA--------KKQSESEDTLP
SFSS-----------------------------------------------------------
>Gorilla_gorilla-PLEKHA3(ENSGGOP_19243)
-----------------------------------------------------------------------MEGVLYKWT
NYLTG---------------------------WQPRWFVLDNGILSYYD-------------------------------
----------SQDDVCKGSKGSIKMAVCEIK--VHSADNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTR
TKKEKEIS-----------------ETSESLKTKMSELRLYCDLLMQQVHTIQ-EFVHH---------------DENHSS
PSAENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMF-QLHHPDPLVSPVS------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------PSPVQM--MKRSVSHPGS
CSSERSSHSIKEPVSTLH------------------------------------------------------RL-----S
QRRRRTYSDTDSCS--------------------DIPLEDPDRPVHCSKNTLNGDLAS----------------------
--------------------------------------------------ATIPEESRLMA--------KKQSESEDTLP
SFSS-----------------------------------------------------------
>Macaca_mulatta-PLEKHA3(ENSMMUP_2920)
-----------------------------------------------------------------------MEGVLYKWT
NYLTG---------------------------WQPRWFVLDNGILSYYD-------------------------------
----------SQDDVCKGSKGSIKMAVCEIK--VHSADNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTR
TKKEKEIS-----------------ETSESLKTKMSELRLYCDLLMQQVHTIQ-EFVHH---------------DENHSS
PSAENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMF-QLPHPDPLVSPVS------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------PSPGQM--MKRSVSHPGS
CSSERSSHSIKEPVSTLH------------------------------------------------------RL-----S
QRRRRTYSDTDSCN--------------------DIPLEDPDRPVHCSKNTLNGDLAS----------------------
--------------------------------------------------ATIPEESRLMA--------KKKSESEDTLP
SFSS-----------------------------------------------------------
>Erinaceus_europaeus-PLEKHA3(ENSEEUP_3777)
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------HSADNTRLELIIPGEQHFYMRAVNAAERQRWL-ALGSSKACLTDTR
TK-GKEIN-----------------ETSESLKTKMSELRLYCDLLMQQVHTIQ-EFVHH---------------DENHSP
PSIENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMF-QLTHPDPLVSPVS------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------PSPVQM--MKRSVSHPGS
CSSERTSHPMKEPVPTFY------------------------------------------------------RF-----S
QRRRRTYSDTDTCN--------------------DIPLEDPDRPVHCSRSTLNGDLAP----------------------
--------------------------------------------------VTIPEESKLTA--------KKTSESEDLLP
SFPS-----------------------------------------------------------
>Bos_taurus-PLEKHA3(ENSBTAP_1453)
-----------------------------------------------------------------------MEGVLYKWT
NYLTG---------------------------WQPRWFVLDNGILSYYD-------------------------------
----------SQDDVCKGSKGSIKMAVCEIK--VHSADNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTR
TKKEKEIS-----------------ETSESLKTKMSELRLYCDLLMKQVHTIQ-EFVHH---------------DESHSS
LSIENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMF-QLSHPDPLVSPVS------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------PSPVQM--MKRSVSHPGS
CSTERSSHSIKEPVSALH------------------------------------------------------RL-----S
QRRRRTYSDTDSCN--------------------DVPLEDPDRPVHCSRNTLNGDLAS----------------------
--------------------------------------------------ATIPEESRFMA--------KKKSESEDPLL
SFSS-----------------------------------------------------------
>Mus_musculus-PLEKHA3(ENSMUSP_107551)
-----------------------------------------------------------------------MEGVLYKWT
NYLTG---------------------------WQPRWFVLDNGILSYYD-------------------------------
----------SQDDVCKGSKGSIKMAVCEIK--VHPADNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTR
TAKEKEIS-----------------ETSESLKTKMSELRLYCDLLMQQVHTIQ-EFVHR---------------DERHPS
PSVENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMF-QLPHPDPLVSPVS------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------PSPVQM--MKRSASHPGS
CSSERSSCSIKEPASALH------------------------------------------------------RL-----P
QRRRRTYSDTDSCN--------------------DVPPEDPERPLHCSGNTLNGDLAS----------------------
--------------------------------------------------ATIPEESRLMA--------KTQSE--EPLL
PFS------------------------------------------------------------
>Rattus_norvegicus-PLEKHA3_(ENSRNOP_16132)
-----------------------------------------------------------------------MEGVLYKWT
NYLTS---------------------------WQPRWFVLDNGILSYYD-------------------------------
----------SQDDVCKGSKGSIKMAVCEIK--VHSADNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTR
TAKEKEIS-----------------ETSESLKTKMSELRLYCDLLMQQVHTIQ-EFVHH---------------DEDHSS
PSVENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMF-QLPHPDPLVSPVS------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------PSPVQM--MKRSASHPGP
CSSERSSCSIKEPASALH------------------------------------------------------RL-----P
QRRRRTYSDTDSCN--------------------DVPPEDPERPLHCSGNTLNGDLAS----------------------
--------------------------------------------------AAIREESRLTA--------KTHSESEEPLP
PFS------------------------------------------------------------
>Oryctolagus_cuniculus-PLEKHA3(ENSOCUP_4767)
-----------------------------------------------------------------------MEGVLYKWT
NYLTG---------------------------WQPRWFVLDNGILSYYD-------------------------------
----------SQDDVCKGSKGSIKMAVCEIK--VHSADNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTR
TKKEKEIS-----------------ETSESLKTKMSELRLYCDLLMQQVHTIQ-EFVHH---------------DESRSS
PSIENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMF-QLPHPDPLVSPVS------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------PSPVQM--MKRSVSHPGS
CNSERSSHCTKEPVSTLH------------------------------------------------------RL-----S
QRRRRTYSDTDSCN--------------------DIPLEESDRPTHCSRNTLNGDLTS----------------------
--------------------------------------------------ATIPEENRLTA--------KKKPESEALLP
PFSS-----------------------------------------------------------
>Loxodonta_africana-PLEKHA3(ENSLAFP_5359)
-----------------------------------------------------------------------MEGVLYKWT
NYLTG---------------------------WQPRWFVLDNGILSYYD-------------------------------
----------SQDDVCKGSKGSIKMAVCEIK--VHSADNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTR
TKKEKEIS-----------------ETSESLKTKMSELRLYCDLLMQQVHTIQ-EFVHH---------------DETHSS
PSVENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMF-QLPHPDPLVSPVS------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------PSPVQM--MKRSVSHPGT
CSSERSSHAVKEPASTLH------------------------------------------------------RL-----S
QRRRRTYSDTDSCN--------------------DIPLEDPERPVHCSRNTLNGDLAS----------------------
--------------------------------------------------AAIPEENKCTA--------KKKSELEDPLP
SFS------------------------------------------------------------
>Monodelphis_domestica-PLEKHA3(ENSMODP_12354)
-----------------------------------------------------------------------MEGVLYKWT
NYLTG---------------------------WQPRWFVLDNGILSYYD-------------------------------
----------SQDDVCKGSKGSIKMAVCEIK--VHPADNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSAKACLTDTR
AKKEKEIS-----------------ETNESLKTKMSELRLYCDLLMQQVHTIQ-EFVHH---------------DDSHSS
PSVENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMF-QLPHPDPLVSPVS------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------PSPVQM--MKRSISHPGS
YSSERSSHTVKEPGPSLH------------------------------------------------------RI-----S
QRRRRTYSDTD-YN--------------------DIPPEDPDRPVHCSRNILNGDLAS----------------------
--------------------------------------------------ATIPEENRTMS--------KKRSELEDVLP
SFSS-----------------------------------------------------------
>Ornithorhynchus_anatinus-PLEKHA3_(ENSOANP_13762)
-----------------------------------------------------------------------LPSVLFHSS
LFIQC---------------------------WQPRWFVLDNGILSYYD-------------------------------
----------SQDDVCKGSKGSIKMAVCEIK--VHPTDNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTR
TKKEKEIS-----------------ETNESLKTKMSELRLYCDLLMQQVHTIQ-EFVHH---------------EENHSS
PSIENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMF-QLPHPDPLVSPVS------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------PSPVQM--MKRSISHPGS
YGSERNSHSMKEQISSFH------------------------------------------------------RL-----S
QQHRRTYSDTDSYN--------------------DSPFEDPDRPILCSRDALNGDLTS----------------------
--------------------------------------------------ATIPEENRSAT--------KKRTELEDPFL
SST------------------------------------------------------------
>Gallus_gallus-PLEKHA3(ENSGALP_32659)
-----------------------------------------------------------------------MEGVLYKWT
NYLAG---------------------------WQPRWFVLDNGILSYYD-------------------------------
----------SQDDVCKGSKGSIKMAVCEIK--VHATDNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSAKACLADTR
TKKEKEIS-----------------ETNESLKTKMSELRLYCDLLMQQVHTIQ-EFVHH---------------DETCSP
PSIENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMF-QLPHPDPLVSPVS------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------PSPVQM--MKRSISHPGP
CYSERDNHSVKEPVSSLH------------------------------------------------------RL-----S
QQRRRTYSDTASYS--------------------DTPPEDSQRSAHCPRNAVNGDLVS----------------------
--------------------------------------------------STIPEENRSIS--------NERSELEGSLS
SFSS-----------------------------------------------------------
>Taeniopygia_guttata-PLEKHA3(ENSTGUP_9483)
-----------------------------------------------------------------------MEGVLYKWT
-TTSG---------------------------WQPRWFVLDNGILSYYD-------------------------------
----------SQDDVCKGSKGSIKMAVCEIK--VHATDNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSAKACLADTR
TKKEKEIS-----------------ETNESLKTKMSELRLYCDLLMQQVHTIQ-EFVHH---------------DETRSP
PSIENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMF-QLPHPDPLVSPVS------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------PSPIQM--MKRSISHPGP
CSSERINHSVKEPGLSLH------------------------------------------------------RV-----S
QRRRRTVSDTESYS--------------------DTLSEDSQGSAHCSRSAVNGDLVS----------------------
--------------------------------------------------STIPEESKSVS--------KERSELEETP-
-FI------------------------------------------------------------
>Anolis_carolinensis-PLEKHA3(ENSACAP_16986)
-----------------------------------------------------------------------YNKKLMLCS
LFALG---------------------------WQPRWFVLDNGILSYYD-------------------------------
----------SQDDVCKGSKGSIKMAVCEIKAKVHPTDSTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTK
TKKEKETN-----------------ETSESLKTKMSELRLYCDLLMQQVHTIQ-EYVHH---------------DKNSSS
PTVENMN-----EASSLLSATCDTFITTLEECVKIAN---AKFKPEMF-QLPHPDPLVSPVS------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------PSPVQM--MKRSVSHPGT
CYPERSGHFTKEPISSSH------------------------------------------------------RL-----S
QKCRRAVSDAGPSI--------------------DIPLEDTDRPASCSRDTLNGDLAPP---------------------
--------------------------------------------------AVLPETSLPLCD------SKKEPELEETLP
PTF------------------------------------------------------------
>Xenopus_tropicalis-PLEKHA3(ENSXETP_32856)
-----------------------------------------------------------------------MEGVLYKWT
NYITG---------------------------WQPRWFVLDNGILSYYD-------------------------------
----------SQDDVCKGSKGSIKMAVCEIK--VHSTDNTRMELIIPGEQHFYVKAVNAAERQRWLVALGSSKACLADNR
TRKEKEIS-----------------ETNESLKTKMSELRLYCDLLMQQVHTIQ-EFVNH---------------DEHRPS
PSTENMN-----EASSLLSATCNTFITTLEECVKIAN---AKFKPEMY-QLVPHD--VSAVS------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------PSPVQM--MKRSMSHPGT
YISEGGSQSYKD--SSFH------------------------------------------------------RA-----T
HRRRSAYSDTETCNN-------------------DVFLEEMEGPAHCLKTGINGDLSP----------------------
--------------------------------------------------ANVQEENRQKS--------KKLCESENSPV
SLSF-----------------------------------------------------------
>Danio_rerio-PLEKHA3(ENSDARP_73572)
-----------------------------------------------------------------------MEGVLYKWT
NYMTG---------------------------WQPRWFVLDNGIISYYD-------------------------------
----------SQDDVCKGSKGSIKMSVCEIK--VHPTDNTRLELIIPGEQHFYVKAVNAAERQKWLVALGSSKAGLIDTR
TKKERELT-----------------ETTESLKTKMSELRLYCDLLMQQVHTIQ-ESVEQ---------------HEEPAV
ANTETRN-----EASSLLSATCETFIKTLEECMKIAN---SKFKTDML-QSSPSDSIMSPVS------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------PSPVQMSRMKRSISHPGT
YNYERSS--LPKDCVAFQ------------------------------------------------------KS-----S
QRRTRTCSDTEAHS--------------------DRGPDDIER-LMFHRANINGDSTP----------------------
---------------------------------------------------SIPEEVGTST--------KFLSETDTPES
DLSL-----------------------------------------------------------
>Oryzias_latipes-PLEKHA3(ENSORLP_24324)
-----------------------------------------------------------------------MEGILYKWT
NYMTG---------------------------WQPRWFVLENGVISYYD-------------------------------
----------SEDDVNKGSKGSIKMSVCDIK--VHPTDSTRLDLIIPGEQHFYVRAVNAAERQRWLVALGSSKAGNLDSK
KHGGEKSR-----------------RCPECLKTKMSELRLYCDLLVQQVQTIQSQNNTG---------------DEATPT
SEVSTLP-------ASLLSATCTTFIQTLEECMSLAN---QSLMPDLR-PAEKVTLSLN----VK---------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------TCLFSSAQMKRSVSHPGT
YSFER-G-MLKECVSGAQ------------------------------------------------------RS-----M
PRRPRTCSDSSVY-------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------
>Gasterosteus_aculeatus-PLEKHA3(ENSGACP_15363)
-----------------------------------------------------------------------MEGILYKWT
NYMTG---------------------------WQPRWFVLEGGVISYYD-------------------------------
----------SEDDVDKGSKGSIKMSVCDIK--VHPTDTTRLELIIPGEQHFYVRAVNAAERQRWLVALGSSKAGTLESH
RHKDRQLA-----------------QSPDCLKTKMSELRLYCDLLVQQVQTIQSQHTSD---------------TEETPT
SESEESE------SSSLLSATCATFIRTLEECMTLAN---QSMTPDLR-PPERVILLLLPMDKTF---------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------PAFVSPAQLKRSTSHPGT
YSFDRSG-VLKEYSSGGQ------------------------------------------------------KS-----S
QRRTRTFSDSSLYDA-------------------ER-----------LLPTLNGDSS-----------------------
----------------------------------------------------IPEER--PDS------PKTTPTDTDTDL
SI-------------------------------------------------------------
>Takifugu_rubripes-PLEKHA3(ENSTRUP_15479)
-----------------------------------------------------------------------MEGILYKWT
NYMTG---------------------------WQPRWFVLENGVISYYD-------------------------------
----------SEDDVGKGSKGSIKMSVCDIK--VHPTDPTRLELIIPGEQHFYVRAVNAAERQRWLVALGSSKAGTLDGH
KHKDIEEKT--------------ETTGPDGLKTKMSELRLYCDLLVQQVQTIQTQYTAD---------------TEAPPT
VEVAHLLFS--PNKASLLSATCSTFIRTLEECMTLAN---QSLTSDLR-PTERVTTPLL-----S---------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------GLL-LFAQMKRSISHPGT
YSFDRSG-VLKEYLSAGQ------------------------------------------------------RS-----A
QRRNRTCSDSFVYDA-------------------EFHACFMRVCFPGASPGFSGDPAI----------------------
----------------------------------------------------IPEERGLSVS------PKTTPTDTDTDL
SI-------------------------------------------------------------
>Tetraodon_nigroviridis-PLEKHA3(ENSTNIP_12769)
-----------------------------------------------------------------------MEGILYKWT
NYMTG---------------------------WQPRWFVLENGVISYYD-------------------------------
----------SEDDVGKGSKGSIKMSVCDIK--VHPTDPTRLELIIPGEQHFYVRAVNAAERQRWLVALGSSKAGTLDSH
KHKDLCLS-----------------AGPDGLKTKMSELRLYCDLLVQQVQTIQTQYSAD---------------TEAAPT
VEVARLP-------ASLLSATCATFIRTLEECMTLAN---QSLTPDLR-PTERVTTPLS-----A---------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------AIFSKITQMKRSISHPGT
YSFDRSG-VLKEYVSAGQ------------------------------------------------------RS-----V
QRRNRTCSDSSVY-------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------
>Oryzias_latipes-PLEKHA9(ENSORLP_9275)
-----------------------------------------------------------------------MEGTLHKWT
NYISG---------------------------WQPRWFVLDGGILSYYD-------------------------------
----------SQEDAWKGCKGSIKISVCEIQ--VHTSDSTRVDLTIPGEQYFYLKAINAAERQKWLVAMGTAKACLTDNR
TKREKE-----------------LQENTEALKTKMSELRLYCDLLLQQVNKIK--ES------------------DELGQ
TVETGLD------TGKMVKSTCTTFLKTLEECMQIAN---RTFSTDVTAHSPPGTPPLAAIKQNKSIKLANHLNLNLGEK
RKD--ASPERSGQSGAEEPEKPEVHPFPS---------------------------------------------------
-----------------------------SKTGFQTAHSPGGSLGK--EPVNPAPGSNQPSPELEHLEQPAEGDEKYDTP
EEKETKQEQNNKVDQSQELPNNSEINGVRLQRETASVQEENGE--DETQKVEDTEQVE--TFFSTMSHRFNDIRLDDDNG
IPTQEFLDSCYAIVPVLD------------------------------------------------------KLGSTVFA
PVKMDFVGNIKKIH------QKLMSDPECFPTLQSIVQHEVRTEVAQVRNSATEALLWLRRGLKFLKEFLSEVNAGERDI
QG-----------------------------------------ALNNAYGKTLRIYHGWVVRGVFALALRAAPCYESFTA
ALVTREGDELHSEFTNS---MHRDLGMYLPAMEKQLAILDELYEEYNLESDEVV---------
>Takifugu_rubripes-PLEKHA9(ENSTRUP_39875)
-----------------------------------------------------------------------MEGMLYKWT
NYISG---------------------------WQPRWFVLEGGTLSYYD-------------------------------
----------SQEDAWKGCKGSIKVSVCEIQ--VHSTDATRVDLTIPGEQYFYLRAINAAERQKWLVALGTAKACLTDNR
TKREKE-----------------LQENTDALKTKMSELRLYCDLLLQQVNKIK--EN------------------DELVD
TAETAID------NGNMVKSTCATFLKTLEECMQIAN---HTFSLDMATQSPPGSPPVAAIKPRK---VSPNIGTDLSEA
PVEPVAHDNHSLDSGPEGPEEPDKPDDLH---------------------------------------------------
-----------------------------NKS--TEVTNTKSVTDE--DMVGPNAHAPQDAPESKHYDATTR------EA
DDKQTDQEQKHKVDQSLEEETCTDAVQHHQEQEAAPDQHQWETC-TDPAEPEDTEQVE--TFFSTMSHRFSDLRLDDDNG
IPTQEFLDSCYAIVPVLD------------------------------------------------------KLGSTVFA
PVKMDFVGNIKKIH------QKLMSDPGSFPTLQSIVLNEVQNNVALVRNSATEALLWLRRGLKFLKEFLSEVNAGQQDI
QG-----------------------------------------ALNNAYGKTLRQYHGWVVRGVFALALRAAPSYQSFSA
ALVLREGDELKSGFTRG---MHRDLGVYLPAMEKQLAILDDLYEEYNLESDEVV---------
>Danio_rerio-PLEKHA9(ENSDARP_59622)
-----------------------------------------------------------------------MEGVLYKWT
NYISG---------------------------WQPRWFVLEGGTLSYYD-------------------------------
----------SQEDAWKGCKGSIKISVCEIQ--VHPSDFTRVDLIIPGEQYFYLRAINAAERQKWLVALGTAKACLTDNR
TKREKE-----------------LQENSEALKTKMSELRLYCDLLLQQVNKIQ--ESPL---------------AETSAG
SGEGGDE------TGNLVKSTCTTFLKTLEECMHIAS---RTFNPDLLSRTPPGSPSVATIKPQK-IKSNDPKNLHPGET
RKD---LINTSGTSAHES--GPDNEPPPS---------------------------------------------------
-----------------------------PQENISTAHTESGLMEDQNDLIEPNNGS---SSSTQDHEEPVE------EQ
QKDGSTEDADHSQEEQQEVSMSPTQNKQEVQEDIQTDLELNETQSENKQEEEDEDKVD--TFFSTMSHRFSDIILEEDSG
IPTQAFLDSCYAIVPVLD------------------------------------------------------KLGPTVFA
PVKIDFVGNIKKIQ------QKVVSDPESFPTLQSIVLHEVKTEVAQVRNSATEALLWLKRGLKFLKEFLYEINTGVKDV
QG-----------------------------------------ALYNAYGKTLRQYHGWVVRGVFALALRAAPSYEGFMA
ALVSYEGDELKEGFRTG---MHRDLDIYLPAMENQLSILDTLYEEYGLESDEIV---------
>Anolis_carolinensis-PLEKHA9(ENSACAP_936)
-----------------------------------------------------------------------QAYVIQLCS
FFFPG---------------------------WQPRWFLLAGGVLSYYD-------------------------------
----------SREDAWKGCKGSIQMAVCEIQ--VHPTDNTRVDLIIPGEQYFYLKSKNAADRQKWLVALGTAKACLTDIR
TLKEK-----------------EFSENTDALKTKMAELRLYCDLLVQQADKTK--VTP----------------LSNVSE
VLQNGVD------TGALLTTTCTTFLKTLDECMQIAN---VAFSSELLYQPTSGSPHSAFYKLNK-LKLPSIFSRGVAER
QMELKNTENGYIYANAN-LPEQTPVLLKT---------------------------------------------------
-----------------------------DDSLYSSKINVIVAIIE--------------------------------KN
NTCNNTNNNRD--GSKKDGKDKLLPKIPDRDTKSLELPADSIGKSTPLSEETNKDFK---TFFSAMSIRFSDIELSEDEG
IPTEEFLRSCYEIVPVLD------------------------------------------------------KLGPTVFA
PVKMDFEGNIKKIN------QKYITSKDDFHTLQKLILHEVSSGDAQLRNSATEALMWLKRGLKFLKEFLIEIKNGEKNI
QT-----------------------------------------ALNHAYGKTLRQYHGWVVRGVFALALRASPTYEGFAL
ALSIGEHKYQEDIFYNS---MQRDLDIYLPAMEKQLSILDALYEEHGLESNEVV---------
>Ornithorhynchus_anatinus-PLEKHA9(ENSOANP_17160)
--------------------------------------------------------------------------------
---SG---------------------------WQPRWFLLCGGILSYYD-------------------------------
----------SPEDAWKGCKGSIQMAVCEIQ--VHPADNTRMDLIIPGEQYFYLKARNVAERQRWLVALGSAKACLTDSR
AQKEK-----------------EFTENTETLKTKMSELRLYCDLLVQQVDKTR--EAT----------------AAGVSG
S-EEGID------VGALLRSTCNTFLKTLEECMQIAN---TTFTSELLYPTPPGSPRLAVLKPSK-MKHPIIPIHNPVER
QMELNSCENGSLNVEVTDSEPTPVTN-ET---------------------------------------------------
-----------------------------PSDLKLAENDGTMSAEE--------------------------------SS
GDGIAFSGQE----TKQAGERGISPASGRCDNDLMPPGGDFLSESTKSQREEEKEEVR--TFFSAMNTSFSDIELLEDSG
IPTEAFLESCYAVVPVLD------------------------------------------------------KLGPTVFA
PVKMDLVGNIKKERDHESCVERIIKNQSVKSQKRRVIVIGAVLKGAYTAKFVGHAEGWADRGNKGLSMERISLKFSNSSL
QT-----------------------------------------VKDNAYGKTLRQHHGWVVRGVFALALRAAPSYEDFVA
ALTVREGDDQKEAFSIG---MERDLNVYLPAMEKQLEILDTL---------------------
>Gallus_gallus-PLEKHA9(ENSGALP_18216)
-----------------------------------------------------------------------MEGVLYKWT
NYLSG---------------------------WQPRWFLLCGGILSYYD-------------------------------
----------SQEDAWKGCKGSIQMAVCEIQ--VHPADNTRMDLIIPGEQYFYLKARNAVERQKWLVALGTAKACLTDSR
TQKEK-----------------EFTENTEALKTKMSELRLYCNLLVQQVHKTK--EAS----------------ISAVSE
P-ESGID------VGALLKSTCDTFLKTLEECMQIAN---TAFTSELLHQTPPGSPHLAVLRTNK-IKHSVLSSHTSTER
QMELNPCENGSIKAENN-QQEQT--LIKS---------------------------------------------------
-----------------------------LACLN-------LETNE--------------------------------RS
SDVSVEDHIEE--VMKEDGENKLQAVESLDAHKLLQTETNSLSGLTLCEEDEDENENGFPTFFSVMSNRFSDIELQEEEG
IPTEEFLESCYAIVPVLD------------------------------------------------------KLGPTVFA
PVKMDFVGNIKKIN------QKFITNKEEFDTLQKIVLHEVSAGVAQVRNSATEALLWLKRGLKFLKGFLTEVKNGEKNI
QT-----------------------------------------ALNNAYGKTLRQHHGWVVRGVFALALRAAPTYEDFVA
ALSVEDCDPQEETFYRA---MQRDLSIYLPAMEKQLNILDTLYEVHGLESDEVV---------
>Taeniopygia_guttata-PLEKHA9(ENSTGUP_3106)
-----------------------------------------------------------------------MEGVLYKWT
NYLSG---------------------------WQPRWFLLCGGILSYYD-------------------------------
----------SQEDAWKGCKGSIQMAVCEIQ--VHPADNTRMDLIIPGEQYFYLKARNAVERQKWLVALGTAKACLTDSR
TQKEKGKNTLLL--------AHNFTENTEALKTKMSELRLYCNLLVQQVHKTK--EAS----------------ISGVSE
P-ESEID------MGALLKSTCDTFLKTLEECMQIAN---TAFTSELLHQTPPGSPNLAVLRMSK-VKHSVLPSHTSTER
QVELNPCENGCVKGEIK-HQEQA--VIKS---------------------------------------------------
-----------------------------LECLN-------LETNE--------------------------------GA
GDIYVEDHVAK--DLANDGEDKLQAVEGCGAHKLLQSETNSLSGLTLCEEERNENDS--PTFFSVMSNRFSDIELQEEEG
IPTEEFLESCYAIVPVLD------------------------------------------------------KLGPTVFA
PVKMDFVGNIKKIN------QKFITNKEEFDTLQKIVLHEVNAGVAQVRNSATEALLWLKRGLKFLKGFLTEVKNGEKNI
QT-----------------------------------------ALNNAYGKTLRQHHGWVVRGVFALALRAAPTYEDFVA
ALSVDECNPQEETFYKG---MQRDLNIYLPAMEKQLNILDTLYEVHGLESDEVV---------
>Monodelphis_domestica-PLEKHA9(ENSMODP_19111)
--------------------------------------------------------------------------HHGCLS
FLFAG---------------------------WQPRWFLLCGGILSYYD-------------------------------
----------SPEDAWKGCKGSIQMAVCEIQ--VHSADNTRMDLIIPGEQYFYLKARNVAERQRWLVALGSAKACLTDIR
AQKEKG----------------EFTENTETLKTKMSELRLYCDLLVQQVNRTK--EAA----------------AAGAAD
P-KEGID------VGTLLKSTCNTFLKTLEECMQIAN---TAFTSELLYRTPPGSPRLAALKPSK-TKLPIMPIHNALER
QIALNSCENGSLNTEGSDSEEALMRN-ES---------------------------------------------------
-----------------------------PSRGRPEMGRSVAAADD--------------------------------GD
DPLAALDDFRPPPPSNLMGLEATLSSTGPLSFSICKPKG------RRAGAAQQEEEVQ--TFFSAMNTSFSDIELLEDSG
IPTEAFLESCYAVVPVLD------------------------------------------------------KLGPTVFA
PVKMDLVGNIKKVN------QKYITNKAEFTTLQKIVLHEVGADVAQVRNSATEALLWLKRGLKFLKGFLTEVRNGEKDI
QT-----------------------------------------ALNNAYGKTLRQHHGWVVRGVFALALRAAPSYEDFVA
ALTIREGDHHKEAFSLG---MQRDLNLYLPAMEKQLDILDNL---------------------
>Pteropus_vampyrus-PLEKHA9(ENSPVAP_12191)
-----------------------------------------------------------------------MEGVLYKWT
NYLSG---------------------------WQPRWFLLCGGILSYYD-------------------------------
----------SPEDAWKGCKGSIQMAVCEIQ--VHSVDNTRMDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSR
TQKEKE-----------------FAENTENLKTKMSELRLYCDLLVQQVGKTK--EVT----------------ATGVSS
S-EEGVD------VGTLLKSTCNTFLKTLEECMQIAN---AAFTSELLYRTPPGSPQLAMLKSSK-MKHPIVPIHNSLER
QMELNNCENGSLNMEINDDEEIVMKN-KS---------------------------------------------------
-----------------------------SLYMKSAEIDCSISSEE--------------------------------NT
DDNITVQGEI----MKEDGEENLGNHD----TNVLQPGSDSSSSSPESQWEEGQEVIP--TFFSTMNTSFSDIELLEDGG
IPTEAFLASCYAVVPVLD------------------------------------------------------KLGPTVFA
PVKMDLVGNIKKVN------QKYITNREEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLTEVKNGEKDI
QT-----------------------------------------ALNNAYGKTLRQHHGWVVRGVFALALRAAPSYEDFVA
ALTVKEGDHQKAAFSVG---MQRDLSLYLPAMEKQLAILDTL---------------------
>Macaca_mulatta-PLEKHA9(ENSMMUP_16456)
---------------------------------------------AAGAPRLLGSGAVRGPAGVGRVAAGAMEGVLYKWT
NYLSG---------------------------WQPRWFLLCGGILSYYD-------------------------------
----------SPEDAWKGCKGSIQMAVCEIQ--VHSVDNTRMDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSR
TQKEKGK---------------FFAENTENLKTKMSELRLYCDLLVQQVDKTK--EVT----------------TTGVSN
S-EEGID------VGTLLKSTCNTFLKTLEECMQIAN---AAFTSELLYRTPPGSPQLAMLKSSK-MKHPIIPIHNSLER
QMELSTCENGSLNMEINGEEEILMKN-KN---------------------------------------------------
-----------------------------SLSLKSAGIDCSISSEE--------------------------------NT
DDNITVQGEI----MKEDGIENLKNHD----NNLTQSGSDSS-CSPECLWEEGKEVIP--TFFSTMNTSFSDIELLEDSG
IPTEAFLASCYAVVPVLD------------------------------------------------------KLGPTVFA
PVDG--------SC------WKY---------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------
>Mus_musculus-PLEKHA9(ENSMUSP_112466)
-----------------------------------------------------------------------MEGVLYKWT
NYLSG---------------------------WQPRWFLLCGGILSYYD-------------------------------
----------SPEDAWKGCKGSIQMAVCEIQ--VHSVDNTRMDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSR
TQKEKE-----------------FAENTENLKTKMSELRLYCDLLVQQVDKTK--EVA----------------TAGVTD
S-EEGID------VGTLLKSTCNTFLKTLEECMQIAN---AAFTSELLYHTPPGSPQLAVLKSSK-MKHPIIPIHNSLER
SMELNSCENGSLSIEVNGDEEILMKT-KS---------------------------------------------------
-----------------------------SLYLKSTEVDCSISSEE--------------------------------NT
DDNVTVQGEI----MKEDGEENLESHD----KDPAQPGSDSV-CSPESPWEDNEEVIP--TFFSTMNTSFSDIELLEDSG
IPTEAFLASCYAVVPVLD------------------------------------------------------KLGPTVFA
PVKMDLVGNIKKVN------QKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLTEVKNGEKDI
QT-----------------------------------------ALNNAYGKTLRQHHGWVVRGVFALALRAAPSYEDFVA
ALTIKEGDHQKEAFSAG---MQRDLSLYLPAMEKQLAILDTLYEIHGLESDEVV---------
>Rattus_norvegicus-PLEKHA9(ENSRNOP_13528)
-----------------------------------------------------------------------MEGVLYKWT
NYLSG---------------------------WQPRWFLLCGGILSYYD-------------------------------
----------SPEDAWKGCKGSIQMAVCEIQ--VHSVDNTRMDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSR
TQKEKE-----------------FAENTENLKTKMSELRLYCDLLVQQVDKTK--EVA----------------TAGVAD
S-EEGID------VGTLLRSTCNTFLKTLEECMQIAN---AAFTSELLYHTPPGSPQLAVLKSSK-MKHPIIPIHNSLER
PIELNSCENGSLSVEVNGDEELLMKTKKS---------------------------------------------------
-----------------------------SLYLKSTKADCNISSEE--------------------------------NT
DGNTTVQGER----MKEDGEENLESHD----RDLAQPGSDSV-CSPESPWEDSEEVIP--TFFSTMNTSFSDIELLEDSG
IPTEAFLASCYAVVPVLD------------------------------------------------------KLGPTVFA
PVKMDLVGNIKKVN------QKYITNKEEFTTLQKIVLHEVEADVARVRNSATEALLWLKRGLKFLKGFLTEVKNGEKDI
QT-----------------------------------------ALNNAYGKTLRQHHGWVVRGVFALALRAAPSYEDFVA
ALTIKEGDHQKEAFSAG---MQRDLSLYLPAMEKQLAILDTLYEIHGLESDEVV---------
>Homo_sapiens-PLEKHA9(ENSP_336073)
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------MSELRLCCDLLVQQVDKTK--EVT----------------TTGVSN
S-EEGID------VGTLLKSTCNTFLKTLEECMQIAN---AAFTSELLYHTPPGSPQLAMLKSSK-MKHPIIPIHNSLER
QTELSTCENGSLNMEINGEEEILMKN-KN---------------------------------------------------
-----------------------------SLYLKSAEIDCSISSEE--------------------------------NT
DDNITVQGEI----MKEDRMENLKNHD----NNLSQSGSDSS-CSPECLWEEGKEVIP--TFFSTMNTSFSDIELLEDSG
IPTEAFLASCCAVVPVLD------------------------------------------------------KLGPTVFA
PVKMDLVENIKKVN------QKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLTEVKNGEKDI
QT-----------------------------------------ALNNAYGKTLRQHHGWVVRGVFALALRATPSYEDFVA
ALTVKEGDHRKEAFSIG---MQRDLSLYLPAMKKQMAILDAL---------------------
>Homo_sapiens-PLEKHA8(ENSP_407802)
---------------------------------------------AAGAPRLLGPGAVRGPAGVGRVAAGAMEGVLYKWT
NYLSG---------------------------WQPRWFLLCGGILSYYD-------------------------------
----------SPEDAWKGCKGSIQMAVCEIQ--VHSVDNTRMDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSR
TQKEKE-----------------FAENTENLKTKMSELRLYCDLLVQQVDKTK--EVT----------------TTGVSN
S-EEGID------VGTLLKSTCNTFLKTLEECMQIAN---AAFTSELLYRTPPGSPQLAMLKSSK-MKHPIIPIHNSLER
QMELSTCENGSLNMEINGEEEILMKN-KN---------------------------------------------------
-----------------------------SLYLKSAEIDCSISSEE--------------------------------NT
DDNITVQGEI----RKEDGMENLKNHD----NNLTQSGSDSS-CSPECLWEEGKEVIP--TFFSTMNTSFSDIELLEDSG
IPTEAFLASCYAVVPVLD------------------------------------------------------KLGPTVFA
PVKMDLVGNIKKVN------QKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLTEVKNGEKDI
QT-----------------------------------------ALNNAYGKTLRQHHGWVVRGVFALALRAAPSYEDFVA
ALTVKEGDHQKEAFSIG---MQRDLSLYLPAMEKQLAILDTLYEVHGLESDEVV---------
>Macaca_mulatta-PLEKHA8(ENSMMUP_16458)
-----------------------------------------------------------------------MEGVLYKWT
NYLSG---------------------------WQPRWFLLCGGILSYYD-------------------------------
----------SPEDAWKGCKGSIQMAVCEIQ--VHSVDNTRMDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSR
TQKEKE-----------------FAENTENLKTKMSELRLYCDLLVQQVDKTK--EVT----------------TTGVSN
S-EEGID------VGTLLKSTCNTFLKTLEECMQIAN---AAFTSELLYRTPPGSPQLAMLKSSK-MKHPIIPIHNSLER
QMELSTCENGSLNMEINGEEEILMKN-KN---------------------------------------------------
-----------------------------SLSLKSAGIDCSISSEE--------------------------------NT
DDNITVQGEI----MKEDGIENLKNHD----NNLTQSGSDSS-CSPECLWEEGKEVIP--TFFSTMNTSFSDIELLEDSG
IPTEAFLASCYAVVPVLD------------------------------------------------------KLGPTVFA
PVKMDLVGNIKKVN------QKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLTEVKNGEKDI
QT-----------------------------------------ALNNAYGKTLRQHHGWVVRGVFALALRAAPSYEDFVA
ALTIKEGDHQKEAFSIG---MQRDLSLYLPAMEKQLAILDTLYEVHGLESDEVV---------
>Anopheles_gambiae-PLEKHA8(XP_565108)
---------------------------------------------MADDYYVQNNSNSDDSEVELNLSSPELKGYLSKWT
NYIHG---------------------------WQPRFIVLKDGTLSYYK-------------------------------
----------SEQDSDFGCRGAISLQKATIK--SHEFDECRFDVAIG-QNVWYLRAETPEDKSNWIEVLQSYKTDQPETV
SLRRHGSTISLQSNTLSTASGSSLKRVSRGLREKLHEIETFRDILYGQIDTLQRYFDALHTK-----------NEDQPPL
DLGDGLKPIDFRGEAITFRETTAGVIITLQHCLDIISQKEESFKKKLDKEQERRRKAEELYRTAKDELAKNRNSVIPGPD
LEEGPHSTIPEDEFFDAVETGLDKIEEDR---------------------------------------------------
----------------------------------QLRVRLKYQSQQ---------------------------------V
SCMQTEALAETEDEIPQLAEDFGTGAQAKSHKLWPEIDRICTEQLTQARQGVGEDGNGWQLFADEGEMKMYRREEEVDGM
VIDPLKSCHVVKGVTAREMCH---------------------------------------------------YFFDPAYR
NDWETTLEDVQIVDN-----VAPDTLVFLQTYKRIWPASQRDALFWSHMRRITDNLDAGANDVWIVCNHSNQNEEYPPAN
QG----------------------------------------------KCVRIYLTVILVCQTYLPPGKDSKTATRDDLT
CKITYCSTVNPGGWAPATVLRAIYKKEYPKFLKRFTGYVVDQCKAKPIMY-------------
>Caenorhabditis_elegans-PLEKHA3(Y47D3A.17c)
MVPNHCVMLDDMQKAAASGISGKNEKKRRAKIDSNEENDDISKRRQNGGNGEIRRDEEKAEKSGDKDPPRQFPSLLTSCS
SFYSSSPSTSTYCSLSSLSPSSLPPPLQKSTKIHRRIMGTLRGRLRQARKQITWCAFPVRARRKAHHRDDESVYESACGD
SEKLFGLQERNPSEVGHTCRGSINLQEARVH----TDKTTSCIVISGQSQTFHVKPQNEMDRQQWTNSLEYMRHKAITRA
ESEEDEDAQMAKT---DSNRSDALILANRQMSGKLCDLRTAANMMNKQGDELMRALN---------------GTVETDKN
SLAERADLL--KMTTSAVLQAAEEFVELSEQSAKRLN---KIVAVEQKEKALLQEQLEALAKQHSSLERAA---------
--SKCARGAAPVSVYSDQEDDEFHDAEED---------------LAMPCSNSNGPPATAGVHLTPTKRHIG---------
--------------------------AGDPSSSTCSDSGAVVVVGAHKGGRQRRTTVPERPNLPINLWSIMKNCIGKELS
KIPMPVNFSEPISVLQRVTEDLEYANLLETGAKLST-LEQMCYVAAYAASNYSTTCHRTNKPFNPLLGETFEFDRMDDLG
WRSVTEQVSHHPPAAAHH-----AEGNGWTMYQDFTMTSRFRGKYLSVIPIGFTHVVFPATKSHFSYRKITTTVHNIIVG
KLWIDNHGDMEITN------HETNEKCLLKFVPYSYFSREQPRKVYGIVRDAEGIPKYVVQGTWDKSIDMLKVSSWNGNH
EK-PKLEVDETSLKRIWTANPLPKNAEKMHNFTKLAIELNEPEEGVAPTDSRLRPDQRLMENGEWDEANRKKLEIEEKQR
VVRRRREAEKELAMKKGDKYEEYEPTWFVRVQDESNGALIHQFKGGYWEAKEQQNWEKCPDIF
>Ciona_savignyi-PLEKHA3(ENSCSAVP_16452)
--------------------------------------------------------------------SDHFKGWLWKWT
NYIKG---------------------------YQRRWFVLSNGLLSYYR-------------------------------
----------SQAEMAHTCRGTINLAGSFIV----TEDSCNFMISNGGTQTFHLKASSEVERQRWITALELAKAKATRFT
ESDDSSDE--------DSLVKNDLRNTLRALVGKLDDLATCNDLISKHGGALQRALSDLESIENNLISQNDSPALSSRIK
TVNERATLF--RITSTAMINACSDFLQLAQNQGKRWH---KAIIHEREQRLRLEETVETLAKQHNTLERALHAGTGPPRP
DPSNKDDESKQTNEIASDDEDEFVDASDK----------------GFTTEFVKDHRKTPSTASSSSIDANN---------
------------------------------ASVVLNTANVSDKSDPDKIIRERRSRIPDKPNYSVNLWSIMKNCIGKDLS
KIPMPVNFNEPLSMLQRLGEDLEYSDILDRAEKCATSQEQMAH------------------PFNPLLGETFELDRRSDLG
FKMICEQVSHHPPAAMHVDSANVSENSGWSYWEEITLVSKFRGKYLNVAPTGVVHLKFHKSGNYYTWRKVTTTVHNIIVG
KLWVDQSGDAEVVN------HTTGDRCKHKYFAYSYFSRETPRKVSGVVQDAKGIAHYVMSGTWDSYMECAKIVTTNNAN
KSKPLYKTLPS--KRLWQVHPLPVGADKMYFLTKLAVTLNEMETGIAPTDSRFRPDQRVMEEGNWDLANDLKQRLEDAQR
SRRKRRE----AAIAMGQEVEPYKPVWFEPQKCQFSGEVTHVYKNSYWESKKAQNWSACPTIF
>Drosophila_melanogaster-PLEKHA3(FBpp_84176)
-------------------------------------------------------MTDAAGNALAEKGLPEMKGWLLKWT
NYIKG---------------------------YQRRWFVLSKGVLSYYR-------------------------------
----------NQSEINHTCRGTISLHGALIH----TVDSCTFVISNGGTQTFHIKAGTEVERQSWVTALELAKAKAIRAI
ECEEEEETETA-----HVVPSQEISSVVRDLTDRLESMRTCYDLITKHGAALQRALNDLETNEE--------ESLGSRTK
IVNERATLF--RITSNAMINAGNDYLHTAEAQGHKWS---KMLHHEREQRQRLEEIIEQMAKQQSQMEQAAVLVR--QNK
PVSSTSGAGTAGSLVTSDEEMEFFDAEEHGYSGSGRSPESSDCERGTFILKMHKRRSSSEDQVEGHLEGSSSESDEQKRT
VQTVQQVCLVSAPRVASGGQGDDDDDVDKALPAKESTDSIYGRNWNPDLIKKRRDRVPDKPNHPISLWGIMKNCIGKDLS
KIPMPINFNEPLSMLQRLVEDYEYTEILDYAATCQDECEQLAYIAAFTVSAYATTTNRTGKPFNPLLGETYECDRMDDYG
WRCLAEQVSHHPPVAALH-----CESKNWTCWQEFSMTSKFRGKYVQINPLGGVYVQFPNSGRRYSWRKVTTTVNNIIVG
KLWVDQHGEMEIRGSQ----AAEGHKCILNFIPYSYFSRDVQRSVKGVVMNKDNEVKWVVRGTWDMKIEIAPVLKTSGSV
SS-PTYTTGEF--KLAWRRRPAPPDSDKFYNFTTLACQLNEEEEGVAPTDSRLRPDQRLMEQGDWDESNKEKLRLEEKQR
TERRRRENEAEEAAAEGRPYPAYEPMWFKREKEEGSEEYVHVFKNTYWEAKAAQNFEGCPDIY
>Anopheles_gambiae-PLEKHA3(XP_309799)
--------------------------------------------------------SSTSVAAAASQPEPDMKGWLLKWT
NYLKG---------------------------YQKRWFVLSKGVLSYYR-------------------------------
----------NQAEMAHTCRGTISLHGALIH----TVDSCTFVISNGGTQTFHIKAANEVERQSWVTALELAKAKAIRAM
ESDEEEEDNTA-----NTIPSEELNLVVRELTVRLENLKTCYDLITKHGAALQRALSELETG----------DDLANKTK
IVSERATLF--RISSNAMINACSDYLQTAQTQGHKWS---KMLQHERDQKLHLEEMVEQLARQHSHLEQAATRHR--PSD
HVSSATKSFNAATSASDDEDNEFYDAQEE---GGSVTQEDSSFILNIPVTTHHNHRRNSNDATGSSSEGEDGNSETQQCR
SLTAGHLSLSFSPRTGISAENLDNMDVTDRISVHSSQALTPTLANQSKVVRKRRTRVPDKPNYPLNLWSIIKNCIGKDLS
KIPMPVNFNEPLSMLQRLTEDFEYSEILDKAAQAKDTCEQLAYVTAFTVSSYSTTSNRTGKPFNPLLGETYECDRTDDLG
WRCINEQVSHHPPMAAQY-----CEGRGWRCWQEFTMTSKFRGKYIQIVPLGYAHVEFPATGNRYTWRKVTTTVHNIIVG
KLWVDNHGDMEIFGER----NAKGVKCHLKYLPYSYFTRDTQRRVKGVVMDSSNQVKWVVNGTWDSKIEIAPVTSTSGST
EN-PVYKTGNY--KTAWTRRMPPPDSDRYYNFTLLACQLNEPEPGVAPTDSRLRPDQRLMEDGKWNESNQEKLRLEEGQR
ARRRQREAEAETAAAEGRPYPPYEPIWFGKEKEEGTDNLVHVYNGTYWDAKAKGDWSKCSTIF