>Homo_sapiens-PDK2(ENSP_420927)
---------------------------------------MRWVWALLKNAS----------------------------L
AGAPKYIEHFSKFSPSPLSMKQFLDFGSSNACEKTSFTFLRQELPVRLANIMKEINLLPDRVLSTPSVQLVQSW-YVQSL
LDIMEFLDKDPEDHRTLSQ--------------------FTDALVTIRN-RHNDVVPTMAQGVLEYKDTYG---DDPVSN
QNIQYFLDRFYLSRISIRMLINQHT---LIFDGSTN--PAHPKHIGSIDPNCNVSEVVK---DAYDM-AKLLCDKYYMAS
PDLEIQEIN-AANSKQPIHMVYVPSHLYHMLFELFKNAMRATVESHE--SSLILPPIKVMVALGEEDLSIK------MSD
RGGGVPLRKIERLFSYMYSTAPTPQPGTGG--TPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLK---ALST
DSVERLPVYNKSAWRHYQTIQEAGDWCVPSTEPKNTSTYRVS-------------
>Macaca_mulatta-PDK2(ENSMMUP_19264)
---------------------------------------MRWVWALLKNAS----------------------------L
AGAPKYIEHFSKFSPSPLSMKQFLDFGSSNACEKTSFTFLRQELPVRLANIMKEINLLPDRVLSTPSVQLVQSW-YVQSL
LDIMEFLDKDPEDHRTLSQ--------------------FTDALVTIRN-RHNDVVPTMAQGVLEYKDTYG---DDPVSN
QNIQYFLDRFYLSRISIRMLINQHT---LIFDGSTN--PAHPKHIGSIDPNCNVSEVVK---DAYDM-AKLLCDKYYMAS
PDLEIQEIN-G----ESVAMCVSVLGLGTQQGKVRWGVRRWTVSRQG--RS------RVIIVLLIHLINIW------TGH
SGS----------HLYMYSTAPTPQPGTGG--TPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLK---ALST
DSVERLPVYNKSAWRHYQTIQEAGDWCVPSTEPKNTSTYRVS-------------
>Gorilla_gorilla-PDK2(ENSGGOP_15203)
ARQGKGREEAAEPRRWAERCASAARAGTTT--QVAAAAAMRWVWALLKNAS----------------------------L
AGAPKYIEHFSKFSPSPLSMKQFLDFGSSNACEKTSFTFLRQELPVRLANIMKEINLLPDRVLSTPSVQLVQSW-YVQSL
LDIMEFLDKDPEDHRTLSQ--------------------FTDALVTIRN-RHNDVVPTMAQGVLEYKDTYG---DDPVSN
QNIQYFLDRFYLSRISIRMLINQHT---LIFDGSTN--PAHPKHIGSIDPNCNVSEVVK---DAYDM-AKLLCDKYYMAS
PDLEIQEIN-AANSKQPIHMVYVPSHLYHMLFELFKNAMRATVESHE--SSLILPPIKVMVALGEEDLSIK------MSD
RGGGVPLRKIERLFSYMYSTAPTPQPGTGG--TPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLK---ALST
DSVERLPVYNKSAWRHYQTIQEAGDWCVPSTEPKNTSTYRVS-------------
>Mus_musculus-PDK2(ENSMUSP_41447)
---------------------------------------MRWVRALLKNAS----------------------------L
AGAPKYIEHFSKFSPSPLSMKQFLDFGSSNACEKTSFTFLRQELPVRLANIMKEINLLPDRVLGTPSVQLVQSW-YVQSL
LDIMEFLDKDPEDHRTLSQ--------------------FTDALVTIRN-RHNDVVPTMAQGVLEYKDTYG---DDPVSN
QNIQYFLDRFYLSRISIRMLINQHT---LIFDGSTN--PAHPKHIGSIDPNCSVSDVVK---DAYDM-AKLLCDKYYMAS
PDLEIQEVN-ATNANQPIHMVYVPSHLYHMLFELFKNAMRATVESHE--SSLTLPPIKIMVALGEEDLSIK------MSD
RGGGVPLRKIERLFSYMYSTAPTPQPGTGG--TPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLK---ALST
DSVERLPVYNKSAWRHYQTIQEAGDWCVPSTEPKNTSTYRVS-------------
>Oryctolagus_cuniculus-PDK2(ENSOCUP_23...
---------------------------------------MRWVRALLKNAS----------------------------L
AGAPKYIEHFSKFSPSPLSIKQFLDFGSSNACEKTSFTFLRQELPVRLANIMKEINLLPDRVLGTPSVQLVQSW-YVQSL
LDIMEFLDKDPEDQRTLNQ--------------------KLVALCTSSTGRRNGEKATVQNGERKKKNKTV---LYLKRL
QNVN-------LCRL-VTVLFLTTA---LLFDGSTN--PAHPKHIGSIDPNCNVSEVVK---DAYDM-AKLLCDKYYMAS
PELDIQEVN-AANSKQPIHMVYVPSHLYHMLFELFKNAMRATVESHE--SSLVLPPIKVMVALGEEDLSIK------MSD
RGGGVPLRKIERLFSYMYSTAPTPQPGTGG--TPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLK---ALST
DSVERLPVYNKSAWRHYQPIQEAGDWCVPSTEPKNTSTYRVS-------------
>Bos_taurus-PDK2(ENSBTAP_11523)
-------GRRGTGPDWAEQSASAARAGSRTRVLEVVAIAMRWVRALLKNAS----------------------------L
AGAPKYIEHFSKFSPSPLSMKQFLDFGSSNACEKTSFTFLRQELPVRLANIMKEINLLPDRVLSTPSVQLVQSW-YVQSL
LDIMEFLDKDPEDHRTLSQ--------------------FTDALVTIRN-RHNDVVPTMAQGVLEYKDTYG---DDPVSN
QNIQYFLDRFYLSRISIRMLINQHT---LLFDGRTN--PAHPKHIGSIDPNCNVSEVVK---DAYDM-AKLLCDKYYMAS
PDLEIQEIN-ASNSKQPIHMVYVPSHLYHMLFELFKNAMRATVESHE--SSVTLPPVKVMVALGEEDLSIK------MSD
RGGGVPLRKIDRLFSYMYSTAPTPQPGTGG--TPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLK---ALST
DSVERLPVYNKSAWRHYQTIQEAGDWCVPSTEPKNTSTYRVS-------------
>Pteropus_vampyrus-PDK2(ENSPVAP_6479)
---------------------------------------MRWVRALLKNAS----------------------------L
AGAPKYIEHFSKFSPSPLSMKQFLDFGSSNACEKTSFTFLRQELPVRLANIMKEINLLPDRVLSTPSVQLVQSW-YVQSL
LDIMEFLDKDPEDRQTLSQ--------------------FTEALVTIRN-RHNDVVPTMAQGVLEYKDAYG---DDPVSN
QNIQYFLDRFYLSRISIRMLINQHT---LIFDGSTN--PAHPKHIGSIDPNCSVSEVVK---DAYDM-AKLLCDKYYMAS
PDLEIQEIS-ASNSKQPIHMVYVPSHLYHILFELFKNAMRATVESHE--SSLILPPIKIMVALGKEDLSIK------MSD
QGGGVPLRKIERLFSYMYSTAPTPQLGTGG--TPLAGFGYGLPISRLYAKYFQGDLHLFSMEGFGTDAVIYLK---ALST
DSVERLPVYNKSAWRHYQTIQEAGDWCVPSTEPKNTSTYRVS-------------
>Monodelphis_domestica-PDK2(ENSMODP_15...
--------------------------------------------------------------------------------
--?PKYIEHFSKFSPSPLSMKQFLDFGSSNACEKTSFTFLRQELPVRLANIMKEINLLPDRVLGTPSVQLVQSW-YVQSL
LDIMEFLDKDPEDHRTLGQ--------------------FTDALVTIRN-RHNDVVPTMAQGVLEYKEAYG---DDPVSN
QNIQYFLDRFYLSRISIRMLINQHT---LIFDGSTN--PAHPKHIGSIDPNCDVSEVVK---DAYDM-AKLLCDKYYMAS
PSLEIQEIN-ASNSKQPIHMVYVPSHLYHMLFELFKNAMRATVESHE--SSLTLPPIKVMVALGEEDLSIK------MSD
RGGGVPLRKIERLFSYMYSTAPTPQLGTGG--TPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLK---ALST
DSVERLPVYNKSAWRHYQTIQEAGDWCVPSTEPKNTSTYRVS-------------
>Taeniopygia_guttata-PDK2(ENSTGUP_15019)
--------------------------------------------------------------------------------
--------------------------GSSNACEKTSFAFLRQELPVRLSNIMKEINLLPDRVLRTPSVQLVQSW-YVQSL
LDIMEFHDRDPEDQATLGQ----------------------AALVSPRA-TPSPGAAGASSGFCQRPHLAG----NPGLN
RAVPRDLFKCSLSVFSHSWHVKILL----LYPDGLF--LMCASVIRKTTQPDSLQESIL---PAVGL-IRLPLILGSGLS
PPIPVSVPTPACNSEQPVSMVYVRSHLYHMLFELFKNAMRATVESHE--SSPRLPAIRVLVALGQEDLSIR------MSD
RGMGVPLRKIERLFSYMYSTAPTPQLGSGG--APL---------------------------------------------
-------------------------------------------------------
>Danio_rerio-PDK2(ENSDARP_12861)
---------------------------------------MKFVRFIMKNAAL----------------------------
ANVPHHIEHFSKFSPSPLSMKQFLDFGSTNACEKTSFVFLRQELPVRLSNIMKEINLLPKRLLTTPSVQMVHSW-YIQSL
MEILEFLEKSPDDHSILEE--------------------FVAALVNIRN-RHNDVVPTMAQGVIEYKEVFGQ---DPVTN
QNIQYFLDRFYLSRISIRMLINQHT---LVFDGATN--PVHPNTIGSIDPHCQVADVVK---DAYES-ARMLCDQYYLNS
PDLDLQELNT-NNRNQPISIVYVPSHLYHILFELFKNAMRATIENHK--EGSNLPAIQVMVAVGGEDLTIK------MSD
RGGGVPFRKMENLFSYMYSTAPTPQMDEKQ-RAPLAGFGYGLPISRLYAKYFQGDLQLYSMEGHGTDAVIHLK---ALST
DSVERLPVFNKTARRNYEVTQGADDWCVPSREPLDLAVFKLAK------------
>Oryzias_latipes-PDK2(ENSORLP_15232)
------------------------------RGAEINTATMKSVRFIMQNAAL----------------------------
ASLPKHIDHFSKFSPSPLSMKQFIDFGSINACEKTSFVFLRQELPVRLSNIMKEINLLPDKLLTTPSVQMVQRW-YIQSL
MEILEFLDKNPDDQQILGD--------------------FADALVTIRN-RHNDVVPTMAQGVMEYKEVFPQ---DVVTN
QNIQYFLDRFYMSRISIRMLINQHT---LVFNGTTN--PAHPTTIGSIEPHCQVGEVVQ---DAFHS-AKMLCDQYYLRS
PDLLLQEMNH-KKTSHPISIVYVPSHLYHMLFELFKNAMRATIETHE--NKNNLPPIKALVSLGGEDMSIK------VSD
VGGGVPFRKIENLFSYMYSTAPTPQIGEHT-RTPLAGFGYGLPISRLYAKYFQGDLQLYSMEGYGTDAVIYLK---ALST
DSVERLPVYNKTALKNYKICQEADDWCVPSKEPLDLRKYRVA-------------
>Takifugu_rubripes-PDK2(ENSTRUP_33230)
---------------------------------------MKFVRFIMKNAAL----------------------------
ASAPKHIEHFSKFSPSPLSMKQFLDFGSINACEKTSFVFLRQELPVRLSNIMKEINLLPDRLLTTPSVQMVQSW-YIQSL
MEILEFLDRNPDDHKVLGQ--------------------FVDTLVTIRN-RHNDVVPTMAQGIIEYKEAFPQ---DPVTN
QNIQYFLDRFYTSRISIRMLINQHT---LIFDGTAN--PVHPNTIGSIDPHCHVGDVVQ---DAFHS-AKMLCDQYYLRS
PDLVLREMS--GKKNPPVSIVYVPSHLYHMLFELFKNAMRATIETHE--SSDHLPPVHVLVSLGDEDVSIK------VCD
TGGGVPFRRIENLFSYMYSTAPAPQLGEHT-RPPLAGFGYGLPISRLYAKYFQGDLQLYSMEGHGTDAVIYLK---ALST
DSIERLPVYNKTALKNYQLRQEADDWCVPSKEPLDLSNYKGPK------------
>Takifugu_rubripes-PDK2(ENSTRUP_21884)
---------------------------------------MKFVRSLMKAAAL----------------------------
ANVPKHIDHFSKFSPSPLSMKQFLDFGTINACERTSFVFLRQELPVRLSNIMKEINLLPDRLLGTPSVQLVQSW-YTQSL
MEILEFLDKTPDDQSVLET--------------------FLEVLETIRN-RHNEVVPTMAQGVIEYKDAFDQQ--DAVTD
HNIQYFLDRFYTSRISIRMLINQHSN--SCVQWQHK--PGSPNTIGCIDSVCDVTEVTR---DAYES-AKLLCEQYYLGA
PELELRQMNA-NNVREPIQISYVPSHLYHMLFELFKNAMRATIETHE--SSRTLPPIKVMIALGGEDLSIK------MSD
RGGGVPFRRTERLFSYMYSTAPRPCIEDKH-RAPLAGFGYGLPISRLYARYFQGDLQLFSMEGNGTDAIIHLK---ALST
DSVERLPVFNKSALRHYKLSLEADDWCVPSKEPLNLANYRAQK------------
>Tetraodon_nigroviridis-PDK2(ENSTNIP_2...
------------------------------------AAAMKLVRFIARSAAL----------------------------
ASAPTHIEHFSKFSPSPLSMKQFLDFGSINACEKTSFVFLRQELPVRLSNIMKEINLLPGRLLTTPSVQMVQSW-YIQSL
MEILEF-DKNPDDHKVLGE--------------------FVDALVTIRN-RHNDVVPTMAQGILEYKEAFPQ---DPVTN
QNIQYFLDRFYTSRISIRMLINQHT---LIFDGSAN--PVHPNTIGSIAPHCQVGDVVQ---DAFHS-AKMLCDQYYLCS
PDLVLQEMSA-GEKKPPISIVYVPSHLYHMLFELFKNAMRATIETHE--NSDQLPPVHVMVALGDEDVSIK------VSD
TGGGVPFRKIENLFSYMYSTAPAPQIGQHA-RTPLAGFGYGLPISRLYAKYFQGDLQLYSMEGHGTDAVIYLK---ALST
DSIERLPVYNKTALKNYRLRQEADDWCVPSKEPLDLSSYKVP-------------
>Tetraodon_nigroviridis-PDK2(ENSTNIP_4...
---------------------------------------MKLVRSLMKTAAL----------------------------
ANVPKHIEHFSKFSPSPLSMKQFLDFGTINACERTSFVFLRQELPVRLSNIMKEINLLPDRLLGTPSVQLVQSW------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------
>Gasterosteus_aculeatus-PDK2(ENSGACP_5...
-------RSLVLPCWSFASLVAKRRNPSREPGPPPKATTMKFVRYIMKNAAL----------------------------
ASVPKHVDHFSKFSPSPLSMKQFLDFGSINACEKTSFVFLRQELPVRLSNIMKEINLLPSKLLTTPSVQTVQSW-YIQSL
MEILEFLDKNPDD-KVLGE--------------------FVDSLVTIRN-RHNHVVPTMAQGIIEYKEAFPQ---DQVTN
QNIQYFLDRFYMSRISIRMLINQHT---LVFDGTLN--PVHPNTIGSIDPHCEVGDVVQGVPDAFRS-AKMLCDQYYLRS
PDLILQEMCRTKKKNLPISIVYVPSHLYHMLFELFKNAMRATIETHD--HSSTLPPVEVMVALGDEDLSIK------MSD
RGGGVPFRRMDKLFSYMYSTAPAPRIGERT-RPPLAGFGYGLPISRLYAQYFQGDLQLFSMEGHGTDAVIYLK---ALST
DSVERLPVYNKTALKNYKVSLEVDDWCIPSREPLDLSVHKVP-------------
>Homo_sapiens-PDK4(ENSP_5178)
---------------------------------------MKAARFVLR-SAGSLNGA-----------------------
GLVPREVEHFSRYSPSPLSMKQLLDFGSENACERTSFAFLRQELPVRLANILKEIDILPTQLVNTSSVQLVKSW-YIQSL
MDLVEFHEKSPDDQKALSD--------------------FVDTLIKVRN-RHHNVVPTMAQGIIEYKDACT---VDPVTN
QNLQYFLDRFYMNRISTRMLMNQHI---LIFSD-SQ--TGNPSHIGSIDPNCDVVAVVQ---DAFEC-SRMLCDQYYLSS
PELKLTQVN-GKFPDQPIHIVYVPSHLHHMLFELFKNAMRATVEHQE--NQPSLTPIEVIVVLGKEDLTIK------ISD
RGGGVPLRIIDRLFSYTYSTAPTPVMDN-SRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYLK---ALSS
ESIEKLPVFNKSAFKHYQMSSEADDWCIPSREPKNLAKEVAM-------------
>Macaca_mulatta-PDK4(ENSMMUP_28178)
---------------------------------------MKAARFVLR-SAGSLSGA-----------------------
GLVPREVEHFSRYSPSPLSMKQLLDFGSENACERTSFAFLRQELPVRLANILREIDILPTQLINTSSVQLVKSW-YIQSL
MDLVEFHEKSPDDQKALSD--------------------FVDTLIKVRN-RHHNVVPTMAQGIIEYKDACT---VDPVTN
QNLQYFLDRFYMNRISTRMLMNQHI---LIFSD-SQ--TGNPTHIGSIDPNCDVVAVVQ---DAFEC-SRMLCDQYYLTS
PELKLTQVN-GKFPDQPIHIVYVPSHLHHMLFELFKNAMRATVEHQE--NRPSLTPIEVIVVLGKEDLTIK------ISD
RGGGVPLRIIDRLFSYTYSTAPTPVMDN-SRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYLK---ALSS
ESIEKLPVFNMSAFKHYQMSSEADDWCIPSREPKNLAKEAAM-------------
>Gorilla_gorilla-PDK4(ENSGGOP_2427)
---------------------------------------MKAARFVLR-SAGSLNGA-----------------------
GLVPREVEHFSRYSPSPLSMKQLLDFGSENACERTSFAFLRQELPVRLANILKEIDILPTQLVNTSSVQLVKSW-YIQSL
MDLVEFHEKSPDDQKALSD--------------------FVDTLIKVRN-RHHNVVPTMAQGIIEYKDACT---VDPVTN
QNLQYFLDRFYMNRISTRMLMNQHI---LIFSD-SQ--TGNPSHIGSIDPNCDVVAVVQ---DAFEC-SRMLCDQYYLTS
PELKLTQVN-GKFPDQPIHIVYVPSHLHHMLFELFKNAMRATVEHQE--NQPSLTPIEVIVVLGKEDLTIK------ISD
RGGGVPLRIIDRLFSYTYSTAPTPVMDN-SRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYLK---ALSS
ESVEKLPVFNKSAFKHYQMSSEADDWCIPSREPKNLAKEVAM-------------
>Mus_musculus-PDK4(ENSMUSP_19721)
---------------------------------------MKAARFVMR-SASSLSSA-----------------------
SLVPREVELFSRYSPSPLSMKQLLDFGSENACERTSFAFLRQELPVRLANILKEIDILPDRLVNTPSVQLVKSW-YIQSL
MDLVEFHEKSPEDQKALSE--------------------FVDTLVKVRN-RHHNVVPTMAQGILEYKDTCT---VDPVTN
QNLQYFLDRFYMNRISTRMLMNQHI---LIFSD-SK--TGNPSHIGSIDPNCDVVAVVQ---DAFEC-AKMLCDQYYLTS
PELNLTQVN-GKFPGQPIHIVYVPSHLHHMLFELFKNAMRATVEHQE--NRPSLTPVEATVVLGKEDLTIK------ISD
RGGGVPLRITDRLFSYTYSTAPTPVMDN-SRNAPLAGFGYGLPISRLYAKYFQGDLNLYSMSGYGTDAIIYLK---ALSS
ESVEKLPVFNKSAFKHYQMSSEADDWCIPSREPKNLAKEKLAV------------
>Oryctolagus_cuniculus-PDK4(ENSOCUP_14...
---------------------------------------MKAARFVMR-SAGSLSGA-----------------------
GLVPREVEHFSRYSPSPLSMKQLLDFGSENACERTSFAFLRQELPVRLANILKEIDILPERLINTSSVQLVKSW-YIQSL
MDLVEFHEKSPDDQKALSD--------------------FVDTLIKVRN-RHHNVVPTMAQGIIEYKDACT---VDPITN
QNLQYFLDRFYMNRISTRMLMNQHI---LIFSD-AQ--TGNPSHIGSIDPNCDVAAVVQ---DAFES-SKMLCDQYYLTS
PELKLTQVN-GKFPGQPIHIVYVPSHLHHMLFELFKNAMRATVEHQE--NWPSLTPIEVIVVLGKEDLTIK------ISD
RGGGVPLRITDRLFSYTYSTAPTPVMDN-SRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYLK---ALSS
ESVEKLPVFNKSAFKHYQMSSEADDWCIPSKEPKNLAKEKVAA------------
>Bos_taurus-PDK4(ENSBTAP_38686)
---------------------------------------MKAARFVMR-SAGTL--------------------------
--IPREVEHFSRYSPSPLSMKQLLDFGSENACERTSFAFLRQELPVRLANILKEIYILPDRLVNTSSVQLVKSW-YMQSL
MELVEFHEKSPEDQKALSD--------------------FVDTLIKVRN-RHHDVIPTMAQGILEYKDACT---VDPVTN
QNLQYFLDRFYMNRISTRMLMNQHI---LIFGD-LQ--TGNPSLIGSIDPNCDVAAVVQ---DAFEC-SKMLCDQYYLTS
PELNLTQVN-VKFPGQPIHIVYVPSHLHHMLFELFKNAMRATVEHQQ--NWPSLTPIQVIVVLGKEDLTIK------ISD
RGGGVPLRVIDRLFSYTYSTAPTPVMDN-SRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLPGYGTDAIIYLK---ALSS
ESIEKLPVFNKSAF-HYQTSSEAGDWCIQAG-TKNLARKKCCV------------
>Pteropus_vampyrus-PDK4(ENSPVAP_11022)
---------------------------------------MRVARFVMR-SAGSL--------------------------
--IPREVEHFSRYSPSPLSMKQLLDFGSESACERTSFAFLRQELPVRLANILKEIDILPDQLINTASVQLVKSW-YIQSL
MDLVEFHERNPEDQKVLSD--------------------FVDTLIEVRN-RHHNVVPTMAQGIIEFKDGCT---VDPITN
QNLQYFLDRFYMNRISTRMLMNQHI---LIFSD-LQ--TRNPSHIGSIDPKCDVVAVVQ---DAFEC-SRMLCDQYYLTS
PELKLTQVN-EKFPGQPIHIVYVSSHLHHMLFELFKNAMRATVEHQE--NQPSLTPIEVIVVLGKEDLTIK------ISD
RGGGVPLRIIDRLFSYTYSTAPTPVMDN-SRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYLK---ALSS
ESIEKLPVFNKSAFKHYQMSNEADDWCVPSKEPKNLANEKVAV------------
>Monodelphis_domestica-PDK4(ENSMODP_20...
--------------------------------------------------------------------------------
------VERFSRYSPSPLSMKQLLDFGSENACERTSFAFLRQELPVRLANILKEIDILPDRLVKTASVQLVKSW-YIQSL
MDLVEFHEKSPDDHKALSD--------------------FVDALIKVRN-RHHDVVPTMAQGILEYKDSGA---ADAGSS
QNLQYFLDRFYMNRISTRMLMNQHI---LIFGE-SK--SGNPSHIGSIDPHCDVVAVVQ---DAYES-ARLLCDQYYLVS
PELKLAQVN-GKLPGQPIHIVYVPSHLHHMLFELFKNAMRATVEHQE--SQPALTPIDVTVVLGNEDLTIKASTFSGISD
RGGGVPLRIIDRLFSYTYSTAPTPVMDN-SRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYLK---ALSS
ESVEKLPVFNKSAFKHYQTSLAADDWCAPSKEPRNLSKEKAEA------------
>Ornithorhynchus_anatinus-PDK4(ENSOANP...
---------------------------------------MNAARLMLR-GAGSLSSS-----------------------
--VPREVEHFSRYSPSPLSIKQLLDFGTENACERTSFAFLRQELPVRLANILKEIDILPDRLVNTSSVQLDKAWVYIQSL
MDLVEFHEKNPDDQKALSD--------------------FIDALITVRN-RNHNVVPTMAQGIIEYKDACP---VDLVTN
QNLQYFLDRFYMNRISTRMLMNQHI---LIFSD-TK--TGNPSHIGSIDPNCDVVSVVQ---DAFES-SLLLCEL--ISR
PEIFLSLLL-GKVPGQPIHIVYVPSHLHHMLFELFKNAMRATVEHQE--NCPSLSPIEVTVVLGKEDLTIK------ISD
RGGGVPLRITDRLFSYTYTTAPTPVMDN-SRNAPLVGDSLASSLPRL---------------------------------
-------------------------------------------------------
>Gallus_gallus-PDK4(ENSGALP_15774)
---------------------RRLADRLTEHPPTAATAAMKAARIALR-TAVPLAGA-----------------GGVRSS
-RLPREVEQFSRFSPSPLSIKQLLDFGSTNGCERTSFAFLRQELPVRFANILREIELLPDKLLSTPSVQLVKSW-YIQSL
MELVEFHQKSPDDQKVLSE--------------------FIDTLIRVRN-RHHDVVPTMAQGVIEYKDMFK---VDPVTN
QNIQYFLDRFYMSRISTRMLMNQHTKTALLFDDKSR--SGHPRHIGSIDPCCDVVEVVN---DAFQS-SKMLCDQYYLTS
PELKLNQVN-GKFPGEPINIVYVPSHLFHMLFELFKNSMRATVEFQE--NSPSLSPVEVTVVLGQEDLAIK------ISD
RGGGVPVRKIEQLFSYMYSTAPRPRMDD-GRQTPLAGFGYGLPISRLYAKYFQGDLNLYSICGYGTDAIIYLK---A---
-------------------------------------------------------
>Taeniopygia_guttata-PDK4(ENSTGUP_1637)
---------------------------------------MKAARIALR-SAAPLAGAN----------------AGSSSG
-RLPKEVEQFSRFSPSPLSIKQLLDFGSTNGCERTSFAFLRQELPVRFANILKEIDLLPDRLLGTPSVKLVKSW-YIQSL
QELIEFHQKSPDDQKVLSD--------------------FIDTLIRVRN-RHHDVVPTMAQGVIEYKDTYK---VDPVTN
QNIQYFLDRFYMSRISTRMLMNQHT---LLFDDKSG--SGHPRHIGSIDPCCDVVEVVN---DAYES-AKLLCDQYYLTS
PELKLTQVN-GKAPGEPISIVYVPSHLFHMLFELFKNSMRATVEFQE--NSPTLSPVEVTVVLGKEDLAIK------VSD
RGGGVPVRKIERLFSYMYSTAPRPNVDD-GRNTPLAGFGYGLPISRLYAKYFQGDLNLYSICGYGTDAIIYLK---ALST
ESIEKLPVFNKSASKHYQATSEADDWCVPSKDPKNMAKQSAAS------------
>Anolis_carolinensis-PDK4(ENSACAP_13895)
---------------------------------------MKAARIALR-NAGPLATTS----------------HGLPSS
GRATREVEHFARYSPSPLSIKQFLDFGSTNACERTSFSFLRHELPVRLANILKEIDLLPSPLLSTPSVQLVKSW-YVQSL
MELVEFHDKKSDDHKVLSD--------------------FIDAIIKVRN-RHHDVVPTMAQGVLEYRDSSK---MDPFIN
QNIQYFLDRFYMNRISIRMLINQHT---LIFDNNNS--IGNPRHIGCIDPCCDVVDLVH---DAFQS-AQMLCDQYYFAS
PELKLTQVN-GKTAGQPIHIVYVPSHLFHMLFELFKNAMRATVEHQE--SKPSLDPVEVTVVLGKEDLSIK------ISD
RGGGVPVRKIESLFSYTYSTAPKPVMDN-NNTTPLAGFGYGLPISRLYAKYFHGDINLCSISGYGTDALIYLK---ALST
ESIEKLPVFNKSACKHYQTPIEADDWCVPSKEPKNLSRQSAAA------------
>Danio_rerio-PDK4(ENSDARP_71589)
---------------------------------------MYICKDFTSVSQCSLLHN-----------------------
IKLARLVTILVCSSRVKFLRSPVLLSGSANACEKTSFMFLRQELPVRLANIMKEIDFLPDKLLGTPSLKLLQSW-YAQSL
MELVDFLEKDPDDKKILTK--------------------FTETLINVRN-RHNNVVPTMAQGVLEYKEAFG---VDPVTN
QNVQYFLDRFYMSRISTRMLMNQHT---LIFDGSTN--PAHPKHIGSIDPNCDVVEVVR---DAYES-SKMLCDQYYLTS
PEVEIKQVN-IKGPSDPIHIVYVPSHLYHMLFELFKNAMRATVETHE--TSLHLPPIKVRVSLGTEDLTIK------MSD
RGSGVPLRKIERLFSYMYSTAPSPVAED-TRNAPLAGFGYGLPISRLYAKYFQGDLQLYSMEGYGTSAVIYLK---ALST
ESIERLPVFNKSALRHYQTSTEADDWCIPSSEPKKLGKYEFSV------------
>Oryzias_latipes-PDK4(ENSORLP_5600)
----------------------------------LTGITMKFAQFWR--SKGSFSG------------------------
--ILKQVERFSKFSPSPLSMKQFIDFGSTNACEKTSFVFLRQELPVRLANIMKEIDYLPDKLLSTPSVKLLNSW-YSRSL
MELVDFLEKDPDDKDVLKN--------------------FTKTLVNVRN-RHNNVVPTMAQGVLEYKDAFG---VDPVTN
QNVQYFLDRFYMSRISTRMLMNQHT---LIFDGSVN--PAHPKHIGSIDPSCDVVEVVK---DAFET-SKMLCEQYYLTS
PDMEITEVN-SKNPDQPLHIVYVPSHLYHMLFELFKNAMRATVETHE--TSPTLPPIKVRISLGSEDLTIK------MSD
KGGGVPLRKIERLFSYMYSTAPSPVHMDNSRNAPLAGFGYGLPISRLYAKYFQGDLQLYSMEGYGTSAVIYLK---ALSS
ESVERLPVFNKSALRHYQTSMEADDWCMPSKDPKKLGKNEMT-------------
>Takifugu_rubripes-PDK4(ENSTRUP_40834)
---------------------------------------MKFGQFLW--KNASVLG------------------------
--IPKQVERFSKFSPSPLSMKQFLDFGSANACEKTSFVFLRQELPVRLANIMKEIDFLPDKLLGTPSLKLLTSW-YSQSL
LDLVEFLEKDPDDKEVLTS--------------------FTQALVNIRN-RHNNVVPTMAQGVLEYKEAFG---VDPVTN
QNVQYFLDRFYMSRISIRMLMNQHT---LIFEGSVN--PAHPKHIGSIDPSCDVVEVVK---DAYET-SKMLCEQYYLTS
PDMEITEVN-SKSPNQPLDIVYVPSHLYHMLFELFKNAMRATVETHE--TSATLPPVKVRVSLGSEDLTIK------MSD
RGGGVPLRKIERLFSYMYSTAPSPVHVDNSRNAPLAGFGYGLPISRLYAKYFQGDLQLYSMEGYGTSAVIYLK---ALSS
ESVERLPVFNKSALRHYRASTEADDWCMPSKDPRKLGKSERTQ------------
>Gasterosteus_aculeatus-PDK4(ENSGACP_8...
---------------------------------------MKFAQFLL--KSSSVSG------------------------
--IPRQVERFAKFSPSPLSMKQFIDFGSADACEKTSFVFLRQELPVRLANIMKEIDFLPDKLLGTPSLKLLISW-YSQSL
MEIVDFLEKDPDDKDVLTN--------------------FTQTLVNVRN-RHNNVVPTLAQGVVEYKDAFG---VDPVTN
QNVQYFLDRFYMSRISTRMLMNQHT---LIFDGSVN--PAHPKHIGSIDPSCAVVEVIK---DAYDT-SKMLCEQYYLTS
PDMEIIEVN-SKNPDQPLHIVYVPSHLYHMLFELFKNAMRATVETHE--TSPALPPIKVRVSLGTEDLTIK------MSD
RGGGVPLRKIERLFSYMYSTAPSPVHMDNSRNAPLAGFGYGLPISRLYAKYFQGDLQLYSMEGYGTSAVIYLK---ALSS
ESVERLPVFNKSALRHYQTSIEADDWCMPSRDPKKLGNSKEKQKYFKLNRTH---
>Homo_sapiens-PDK1(ENSP_376352)
---------------------------------------MRLARLLRGAALAGPGPGLRAAGF--SRSFSSDSGSSPASE
RGVPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLANIMKEISLLPDNLLRTPSVQLVQSW-YIQSL
QELLDFKDKSAEDAKAIYERPRRTWLQVSSLCCMACKMIFTDTVIRIRN-RHNDVIPTMAQGVIEYKESFG---VDPVTS
QNVQYFLDRFYMSRISIRMLLNQHS---LLFGGKGKGSPSHRKHIGSINPNCNVLEVIK---DGYEN-ARRLCDLYYINS
PELELEELN-AKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHA-NRG-VYPPIQVHVTLGNEDLTVK------MSD
RGGGVPLRKIDRLFNYMYSTAPRPRVETSR-AVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIK---ALST
DSIERLPVYNKAAWKHYNTNHEADDWCVPSREPKDMTTFR----SA---------
>Macaca_mulatta-PDK1(ENSMMUP_38143)
--------------------------------------------------------------------------------
--------------------------GSVNACEKTSFMFLRQELPVRLANIMKEISLLPDNLLRTPSVQLVQSW-YIQSL
QELLDFKDKSAEDAKAIYERPK-TWLQVSSLFSMACK-IFTDTVIRIRN-RHNDVIPTMAQGVIEYKESFG---VDPVTS
QNVQYFLDRFYMSRISIRMLLNQHS---LLFGGKGKGSPSHRKHIGSINPNCNVVEVIK---DGYEN-ARRLCDLYYINS
PELELGELN-AKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHA-NRG-VYPPIQVHVTLGNEDLTVK------MSD
RGGGVPLRKIDRLFNYMYSTAPRPRVETSR-AVPLVLCFCQLPSTCSSCQISGIRINKILIECYLICFFFFFQ---ALST
DSIERLPVYNKAAWKHYNTNHEADDWCVPSREPKDMTTFR----SA---------
>Gorilla_gorilla-PDK1(ENSGGOP_4049)
---------------------------------------MRLARLLRGAALAGPGPGLRAAGS--SRSFSSDSGSSPASE
RGVPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLANIMKEISLLPDNLLRTPSVQLVQSW-YIQSL
QELLDFKDKSAEDAKAIYERPRRTWLQVSSLCCMACKMIFTDTVIRIRN-RHNDVIPTMAQGVIEYKESFG---VDPVTS
QNVQYFLDRFYMSRISIRMLLNQHS---LLFGGKGKGSPSHRKHIGSINPNCNVVEVIK---DGYEN-ARRLCDLYYINS
PELELEELN-AKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHA-NRG-VYPPIQVHVTLGNEDLTVK------MSD
RGGGVPLRKIDRLFNYMYSTAPRPRVETSR-AVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIK---ALST
DSVERLPVYNKAAWKHYNTNHEADDWCVPSREPKDMTTFR----SA---------
>Mus_musculus-PDK1(ENSMUSP_6669)
---------------------------------------MRLARLLRGGTSVRPLCAVPCASR--SLASASASGSGPASE
LGVPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLANIMKEISLLPDNLLRTPSVQLVQSW-YIQSL
QELLDFKDKSAEDAKTIYE--------------------FTDTVIRIRN-RHNDVIPTMAQGVTEYKESFG---VDPVTS
QNVQYFLDRFYMSRISIRMLLNQHS---LLFGGKG--SPSHRKHIGSINPNCDVVEVIK---DGYEN-ARRLCDLYYVNS
PELELEELN-AKSPGQTIQVVYVPSHLYHMVFELFKNAMRATMEHHA-DKG-VYPPIQVHVTLGEEDLTVK------MSD
RGGGVPLRKIDRLFNYMYSTAPRPRVETSR-AVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIK---ALST
ESVERLPVYNKAAWKHYKANHEADDWCVPSREPKDMTTFR----SS---------
>Oryctolagus_cuniculus-PDK1(ENSOCUP_357)
--------------------------------------------------------------------------------
--------------------------GSVNACEKTSFMFLRQELPVRLANIMKEISLLPDNLLRTPSVQLVQSW-YIQSL
QELLDFKDKSAEDAKAVYD--------------------FTDTVIRIRN-RHNDVIPTMAQGVIEYKESFG---VDPVTS
QNVQYFLDRFYMSRISIRMLLNQHS---LLFGGKG--SPSHRKHIGSINPNCNVVEVIK---DGYEN-ARRLCDLYYINS
PELELEELN-AKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHA-DKG-VYPPIQVHVTLGNEDLTVK------MSD
RGGGVPLRKIDRLFNYMYSTAPRPRVETSR-AVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIK---ALST
ESIERLPVYNKAAWKHYNTNHEADDWCVPSREPKDMTTFR----SA---------
>Bos_taurus-PDK1(ENSBTAP_38331)
---------------------------------------MRLARLLRVATSAGPGPELRAAGPSVSRSLTSDSGSGPAPE
RGVPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLANIMKEISLLPDNLLRTPSVQLVQSW-YIQSL
QELLEFKDKSAEDAKTIYD--------------------FTDTVIRIRN-RHNDVIPTMAEGVVEYKESFG---VDPVTS
QNVQYFLDRFYMSRISIRMLLNQHS---LLFGGKGKGSLSHRKHVGSINPNCSVVEVIK---DGYEN-ARRLCDLYYINS
PELELEELN-AKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHA-DKG-VYPPIQVHVTLGKEDLTVK------MSD
RGGGVPLRKIDRLFNYMYSTAPRPRVETSR-AVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIK---ALST
ESIERLPVYNKAAWKHYNTNHEADDWCVPSREPKDMTTFR----SA---------
>Pteropus_vampyrus-PDK1(ENSPVAP_10686)
---------------------------------------MRLARLLRGAASAGPGP--RTFRSSASRSLTSDSGSGPAPE
RGVPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLANIMKEISLLPDNLLRTPSVQLVQSW-YIQSL
QELLDFKDKSADDAKTIYERSIKTCLWVSSL-AVVCKIIFTDTVIRIRN-RHNDVIPTMAQGVIEYKESFG---VDPVTS
QNVQYFLDRFFMSRISIRMLLNQHS---LLFGGKNKGSPSHRKHIGSINPNCNVVEVIQ---DGYEN-ARRLCDLYYINS
PELELEELN-AKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEYHA-DKG-VYPPIQVHITLGNEDLTVK------MSD
RGGGVPLRKIDRLFNYMYSTAPRPRVETSR-AAPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIK---ALST
DSIERLPVYNKAAWKHYNTNHEADDWCVPSREPKDMTTFR----SA---------
>Monodelphis_domestica-PDK1(ENSMODP_11...
---------------------------------------MRLVRYLRRAVSASPGP---------GPGPSPNPGPGAGPE
RSVPGPVDFYSRFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLANIMKEISLLPDNLLRTPSVQLVQSW-YIQSL
QELLYFKNKSAEDAKAVYD--------------------FTDTVIRIRN-RHNDVIPTMAQ-CDEYKESFG---VDPVTS
QNVQYFLDRFYMSRISIRMLLNQHS---LLFGGKGKGSSTHRKHIGSINPNCNVVEVIK---DGYEN-AKRLCDLYYVNS
PELELEELN-AKSPGQPMQVVYVPSHLYHMVFELFKNAMRATMEHHA-DKG-VYPPIQVHVTLGNEDLTVK------MSD
RGGGVPLRKIDRLFNYMYSTAPRPRVETSR-AVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIK---ALST
ESVERLPVYNKAAWKHYNTNHEADDWCVPSSEPKDMTTFR----SV---------
>Ornithorhynchus_anatinus-PDK1(ENSOANP...
--------------------------------------------------------------------------------
--------------------------GSVNACEKTSFMFLRQELPVRLANIMKEISLLPDNLLRTPSVQLVQSW-YIQSL
QELLDFKDKSAEDSKTIYD--------------------FTDTVITIRN-RHNDVIPTMAQGVVEYKESFG---VDPVTS
QNVQYFLDRFYMSRISIRMLLNQHS---LLFGGKNKGSTAHRKHIGSINPNCNVVEVIK---DGYEN-ARSLCDLYYINS
PELKLVELN-AKSPGQPMQVVYVPSHLYHMVFELFKNAMRATMEHHA-DKG-VYPPIHVHVTLGNEDLTVK------MSD
RGGGVPLRKIDRLFNYMYSTAPRPRVETSR-AVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIK---ALST
ESVERLPVYNKSAWKHYKTNHEADDWCVPSSEPKDMTTFR----SA---------
>Gallus_gallus-PDK1(ENSGALP_21580)
---------------------------------------MRLLRALLRCASP----------------------------
GSIPQQVDFYSRFSPSPLSMKQFLDFGSENACEKTSFMFLRQELPVRLANIMKEISLLPDNLLRTPSVQLVQSW-YVQSL
QEILDFKDKSSEDSGAIHS--------------------FTDTVIKIRN-RHNDVIPTMAQGVIEYKESFG---IDPVTS
QNVQYFLDRFYMSRISIRMLLNQHS---LLFGGKIN--PAHPKHIGSIDPSCNVVGVIR---DGYES-AKSLCDLYYMSS
PELVLEELN-IKSPGQPMQVVYVPSHLYHMVFELFKNAMRATMEHNA-DRC-IYPPIHVHVTLGNEDLTVK------MSD
RGGGVPMRKIDRLFNYMYSTAPRPRVETSR-ATPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIK---ALST
ESIERLPVYNKAAWKHYKANHEADDWCVPSSEPKDMTTFR----ST---------
>Taeniopygia_guttata-PDK1(ENSTGUP_8792)
---------------------------------------MRLLRALLRGAAA----------------------------
GNIPQQVDFYSRFSPSPLSMKQFLDFGSENACEKTSFMFLRQELPVRLANIMKEISLLPDNLLRTPSVQLVQSW-YVQSL
QEILDFKDKSSEDSGAIHS--------------------FTDTVIKIRN-RHNDVIPTMAQGVIEYKESFG---IDPVTS
QNVQYFLDRFYMSRISIRMLLNQHS---LLFGGKIN--PAHPKHIGSIDPNCNVVEVIR---DGYEN-AKTLCDLYYMSS
PELILEELN-SKSPGQPMQVVYVPSHLYHMVFELFKNAMRATMEHHA-DRS-IYPAIHVHITLGNEDLTVK------MSD
RGGGVPMRKIDRLFNYMYSTAPRPRVETSR-ATPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIK---ALST
ESIERLPVYNKAAWKHYKANHEADDWCVPSSEPKDMTTFR----SM---------
>Danio_rerio-PDK1(ENSDARP_22009)
---------------------------------------MRIFRTLLN--------------------------------
-AASKQIDFYSRFSPSPLSMKQFIDFGSENACEKTSFTFLRQELPVRLANIMKEIDLLPDNLLRTPSVRLVQSW-YMQSF
QDILEFKDKDADDETVNHD--------------------FTDAVIKIRN-RHNDVVPTMAQGVVEYKETYG---TDPITS
QNMQYFLDRFYMSRISIRMLLNQHT---LLFGGKVRDNPAHPKQIGSIDPSCRVTDVVK---DAYEN-ARNLCDRYYMNS
PELVLEEFN-VKGPDKPVTVVYVPSHLYHMVFELFKNAMRATMELYE-DAM-EYPPVHVQIVLGHEDLTVK------VSD
RGGGVPLRKIDRLFTYTYSTAPRPQMDTSR-ATPLAGYGYGLPISRLYARYFQGDLKLYSMEGFGTDAVIYIR---ALST
DSIERLPVYNKSAWKHYKTIHEADDWCVPSKEPKDMTTFR----SF---------
>Oryzias_latipes-PDK1(ENSORLP_21782)
---------------------------------------MRLLRFLR-------------------------------KS
VAVGKDIDYYSKFSPSPLSMKQFLDFGSENACEKTSFAFLRQELPVRLANIMKEINLLPDNLLRTSSVSLVQSW-YMQSF
QDILKFKDKNADNEKVTHE--------------------FTDAVIKIRN-RHNDVIPTMAQGVVEYKETYG---TDPVVS
QNVQYFLDRFYMSRISIRMLLNQHT---LLFGGKV--NPAHPKQIGSIDPHCHVTEVIK---DAYEN-ARNLCDRYYMNS
PDLILEEFN-AKEPGSPVTVVYVPSHLYHMVFELFKNAMRATMELCG-DTM-ECPPIQAQVALGSEDLTVK------VSD
RGGGVPMRKIDRLFTYTYSTAPRPSIDGSS-GAPLAGYGYGLPISRLYARYFQGDLKLYSLEGYGTDAVIYIR---ALST
ESIERLPVYNKSAWKHYKTIHEADDWCVPSKEPKDMTTFR----SF---------
>Takifugu_rubripes-PDK1(ENSTRUP_45340)
---------------------------------------MRILRFLR-------------------------------SS
ISAGKDIDYYSKFSPSPLSMKQFLDFGSENACEKTSFAFLRQELPVRLANIMKEINLLPDNLLRTPSVRLVQSW-YMQSF
QDILEFRDRNAEDEKVTHESVKVYILLVSGL-------SFTNAVIKIRN-RHNDVIPTMAQGVVEYKETYG---TDPVVS
QNVQYFLDRFYMSRISIRMLLNQHT---LIFGGKV--NPAHPKQIGGIDPHCRVSDVVR---DAFEN-ARNLCDRYYMNS
PELVLEEFN-VEEKEKPITVVYVPSHLYHMVFELFKNAMRATMELYG-DAM-EYPAVHAQVALGNEDLTVK------VSD
RGGGVPLRKIDRLFTYTYSTAPRPSLDGSR-AAPLAGYGYGLPISRLYARYFQGDLKLYSLEGHGTDAVIYIR---ALST
ESIERLPVYNKSAWKHYKTIHEADDWCVPSKEPKDMTTFR----SF---------
>Tetraodon_nigroviridis-PDK1(ENSTNIP_2...
-------------------------QLLCRILLIKLNTRLTLLPCQRRQASRQTAT-----------------GSDDKNS
VSAGKDIDYYSKFSPSPLSMKQFLDFGSENACEKTSFAFLRQELPVRLN-IMKEINLLPDNLLRTPSVRLVQSW-YMQSF
QDILEFRDRNAEDEKVTHD--------------------FTDAVIKIRN-RHNDVVPTMAQGVVEYKETYG---TDPVVS
QNVQYFLDRFYMSRISIRMLLNQHT---LLFGGKV--NPAHPNQIGSIDPHCGVSEVVR---DAFEN-ARNLCDRYYMNS
PELVLEEFN-VEEKGKPVTVVYVPSHLYHMVFELFKNAMRATMELYG-DAM-EYPAIHAQVALGNEDLTVK------VSD
RGGGVPLRKIERLFTYTYSTAPRPSLDGSR-AAPLAGYGYGLPISRLYARYFQGDLKLYSMEGHGTDAVIYIR---ALST
ESIERLPVYNKSAWKHYKTIHEADDWCVP-KEPKDMTTFR----SF---------
>Homo_sapiens-PDK3(ENSP_387536)
---------------------------------------MRLFRWLLK--------------------------------
QPVPKQIERYSRFSPSPLSIKQFLDFGRDNACEKTSYMFLRKELPVRLANTMREVNLLPDNLLNRPSVGLVQSW-YMQSF
LELLEYENKSPEDPQVLDN--------------------FLQVLIKVRN-RHNDVVPTMAQGVIEYKEKFG---FDPFIS
TNIQYFLDRFYTNRISFRMLINQHT---LLFGGDTN--PVHPKHIGSIDPTCNVADVVK---DAYET-AKMLCEQYYLVA
PELEVEEFN-AKAPDKPIQVVYVPSHLFHMLFELFKNSMRATVELYE-DRKEGYPAVKTLVTLGKEDLSIK------ISD
LGGGVPLRKIDRLFNYMYSTAPRPSLEPTR-AAPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLK---ALSS
ESFERLPVFNKSAWRHYKTTPEADDWSNPSSEPRDASKYK---AKQDKIKTNRTF
>Macaca_mulatta-PDK3(ENSMMUP_16843)
---------------------------------------MRLFRWLLK--------------------------------
QPVPKQIERYSRFSPSPLSIKQFLDFGRDNACEKTSYMFLRKELPVRLANTMREVNLLPDNLLNRPSVGLVQSW-YMQSF
LELLEYENKSPEDPQVLDN--------------------FLQVLIKVR--RHNDVVPTMAQGVTIVISPKC---F-PVVN
LLTCIFGCRNFISSLVFQLLTHQLS---LLFGGDTN--PVHPKHIGSIDPTCNVADVVK---DAYET-AKMLCEQYYLVA
PELEVEEFN-AKAPDKPIQVVYVPSHLFHMLFELFKNSMRATVELYE-DRKEGYPAVKTLVTLGKEDLSIK------ISD
LGGGVPLRKIDRLFNYMYSTAPRPSLEPTR-AAPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLK---ALSS
ESFERLPVFNKSAWRHYKTTPEADDWSNPSSEPRDASKYK---AKQ---------
>Gorilla_gorilla-PDK3(ENSGGOP_26417)
---------------------------------------MRLFRWLLK--------------------------------
QPVPKQIERYSRFSPSPLSIKQFLDFGRDNACEKTSYMFLRKELPVRLANTMREVNLLPDNLLNRPSVGLVQSW-YMQSF
LELLEYENKSPEDPQVLDN--------------------FLQVLIKVRN-RHNDVVPTMAQGVIEYKEKFG---FDPFIS
TNIQYFLDRFYTNRISFRMLINQHT---LLFGGDTN--PVHPKHIGSIDPTCNVADVVK---VLSQTKAKVHCDIWYLVY
VSLHCDDFS-AKAPDKPIQVVYVPSHLFHMLFELFKNSMRATVELYE-DRKEGYPAVKTLVTLGKEDLSIK------ISD
LGGGVPLRKIDRLFNYMYSTAPRPSLEPTR-AAPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLK---ALSS
ESFERLPVFNKSAWRHYKTTPEADDWSNPSSEPRDASKYK---AKQ---------
>Mus_musculus-PDK3(ENSMUSP_36604)
---------------------------------------MRLFYRLLK--------------------------------
QPVPKQIERYSRFSPSPLSIKQFLDFGRDNACEKTSYMFLRKELPVRLANTMREVNLLPDNLLNRPSVGLVQSW-YMQSF
LELLEYENKSPEDPRVLDN--------------------FLNVLINIRN-RHNDVVPTMAQGVIEYKEKFG---FDPFIS
SNIQYFLDRFYTNRISFRMLINQHT---LLFGGDTN--PAHPKHIGSIDPTCNVADVVK---DAYET-AKMLCEQYYLVA
PELEVEEFN-AKAPNKPIQVVYVPSHLFHMLFELFKNSMRATVELHE-DKKEGYPAVKTLVTLGKEDLSIK------ISD
LGGGVPLRKIDRLFNYMYSTAPRPSLEPTR-AAPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLK---ALSS
ESFERLPVFNKSAWRHYKTTPEADDWSNPSSEPRDASKYK---AKQDKIKSNRTF
>Oryctolagus_cuniculus-PDK3(ENSOCUP_6414)
---------------------------------------MRLFQWLLK--------------------------------
QPVPKQIERYSRFSPSPLSIKQFLDFGRDNACEKTSYMFLRKELPVRLANTMREVNLLPDNLLNRPSVGLVQSW-YMQSF
LELLEYENKSPEDPQVLDN--------------------FLQVLIKVRN-RHNDVVPTMAQGVIEYKEKFG---FDPFIS
SNIQYFLDRFYTNRISFRMLINQHT---LLFGGDTN--PAHPKHIGSIDPTCNVADVVK---DAYET-AKMLCEQYYLVA
PELEVEEFN-AKAPDKPIQVVYVPSHLFHMLFELFKNSMRATVELYE-DRKEGYPAVKTLVTLGKEDLSIK------ISD
LGGGVPLRKIDRLFNYMYSTAPRPSLEPTR-AAPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLK---ALSS
ESFERLPVFNKSAWRHYKTTPEADDWSNPSREPRDASKYK---AKQDKIKTNRTF
>Bos_taurus-PDK3(ENSBTAP_23706)
---------------------------------------MRLFRLLLK--------------------------------
QPVPKQIERYSRFSPSPLSIKQFLDFGRDNACEKTSYMFLRKELPVRLANTMREVNLLPENLLNRPSVGLVQSW-YMQSF
LELLEYENKSPEDPQVLDN--------------------FLQVLIKVRN-RHNDVVPTMAQGVIEYKEKFG---FDPFIS
SNIQYFLDRFYTNRISFRMLINQHT---LLFGGDTN--PVHPKHIGSIDPTCNVADVVK---DAYET-AKMLCEQYYLVA
PELEVEEFN-AKAPNKPIQVVYVPSHLFHMLFELFKNSMRATVELYE-DRKEGYPAVKTLVTLGKEDLSIK------ISD
LGGGVPLRKIDRLFNYMYSTAPRPSLEPTR-AAPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLK---ALSS
ESFERLPVFNKSAWRHYKSTAEADDWSNPSSEPRDASKYK---AKQDKMKTNRTL
>Pteropus_vampyrus-PDK3(ENSPVAP_855)
--------------------------------------------------------------------------------
---------------------------RDNACEKTSYMFLRKELPVRLANTMREVNLLPDNLLNRPSVGLVQSW-YMQSF
LELLEYENKSPEDPKVLDN--------------------FLQVLIKVRN-RHNDVVPTMAQGVIEYKEKFG---FDPFIS
SNIQYFLDRFYTNRISFRMLINQHT---LLFGGDTN--PAHPKHIGSIDPACSVADVVK---DAYET-AKMLCEQYYMAA
PELEVEEFN-AKAPNKPIQVVYVPSHLFHMLFELFKNSMRATVELYE-DRKESYPSVKTLVTLGKEDLSIK------ITD
LGGGVPLRKIDRLFNYMYSTAPKPSLEPSR-AAPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLK---ALSS
ESFERLPVFNKSAWRHYKTTPEADDWSNPSSEPRDASKYK---AKQ---------
>Erinaceus_europaeus-PDK3(ENSEEUP_12850)
--------------------------------------------------------------------------------
---------------------------RDNACEKTSYMFLRKELPVRLANTMREVNLLPDNLLNRPSVGLVQSW-YMQSF
LELLEYENKSPEDPQVLDN--------------------FLQVLINVRN-RHNDVVPTMAQGVIEYKEKFG---FDPFIS
SNIQYFLDRFYTNRISFRMLINQHT---LLFGGDTN--PAHPKHIGSIDPTCNVADVVK---DAYET-AKMLCEQYYLVA
PELEIEEFN-AKAPDKPIQVVYVPSHLFHMLFELFKNSMRATVELYE-DRKEAYPAVKTLVTLGKEDLSIK------ISD
QGGGVPLRKIDRLFNYMYSTAPRPSLEPTR-AAPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLK---ALSS
ESFERLPVFNKSAWRHYKTTPEADDWSNPSSEPRDASKYK---VKQ---------
>Monodelphis_domestica-PDK3(ENSMODP_9219)
---------------------------------------MRLYRWLLK--------------------------------
QPVPKQIEQYSRFSPSPLSIKQFLDFGRDNACEKTSYMFLRKELPVRLANTMREVNLLPDNLLSRPSVGLVQSW-YMQSF
LEFLEYENKSPEDQQVLDD--------------------FLQDLIKVRN-RHNDVVPTMAQGVIEYKEKYG---FDPFIS
SNIQYFLDRFYTNRISFRMLINQHT---LLFGDDTN--PSHPKHIGSIDPNCNVAEVVK---DAYET-AKMLCEQYYMVA
PELEVEEFH-AKAPDKPIQVVYVPSHLFHMLFELFKNSMRATVELYE-NRKEGYPSIKTLVTLGKEDLSIK------ISD
HGGGVPLRKIDRLFNYMYSTAPRPSLEPSR-AAPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLK---ALSS
ESFERLPVFNKSAWRHYKTTPEADDWSNPSSEPKDASKYR---AKLDKIKTNRTF
>Gallus_gallus-PDK3(ENSGALP_26284)
---------------------------------------MRLCGALLK--------------------------------
SPIPKQIEYYSRFSPSPLSIKQFLDFGRDNACEKTSYMFLRKELPVRLANTMREVNLLPDNLLNRPSVGLVQSW-YMQSF
LELLEYENKSPEDPHVLDD--------------------FLDVLIKVRN-RHNDVVPTMAQGVIEYKEKYG---FDPFVS
SNIQYFLDRFYTNRISFRMLINQHT---LLFGGDIN--PAHPKHIGSIDPNCNVAEVVK---DAYET-AKMLCEQYYLVA
PDLEVEEFN-AKAPNKPIQVVYVPSHLFHMLFELFKNSMRATVELHE-GKREGYPSIKTLVTLGKEDLSIK------ISD
QGGGVPLRKIDRLFNYMYSTAPRPSLEPTR-AVPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGSDAVIYLK---ALSS
ESFERLPVFNKSAWRHYKTTPEADDWSNPSSEPRDASKYK---ANR---------
>Taeniopygia_guttata-PDK3(ENSTGUP_7416)
---------------------------------------MRLCGAMLK--------------------------------
SPIPKQIEYYSRFSPSPLSIKQFLDFGRDNACEKTSYMFLRKELPVRLANTMREVNLLPDNLLNRPSVGLVQSW-YMQSF
LELLEYENKSPEDPHVLDD--------------------FLDVLIKVRN-RHNDVVPTMAQGVIEYKEKYG---FDPFVS
SNIQYFLDRFYTNRISFRMLINQHT---LLFGGDIN--PAHPKHIGSIDPNCDVTEVVK---DAYET-AKMLCEQYYTVA
PDLEIEEFN-AKAPNKPIQVVYVPSHLFHMLFELFKNSMRATVELHE-GKKEAYPSIKTLVTLGKEDLSIK------ISD
QGGGVPLRKIERLFNYMYSTAPRPSLEPSR-AVPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGSDAVIYLK---ALSS
ESFERLPVFNKSAWRHYKTTPEADDWSNPSSEPRDASKYK---ANR---------
>Anolis_carolinensis-PDK3(ENSACAP_7054)
--------------------------------------------------------------------------------
--------------------------GRDNACEKTSYMFLRKELPVRLANTMREVNLLPDNLLNRPSVKLVQSW-YMQSF
LELLEYENKSPEDPHVLDN--------------------FLDILIKVRN-RHNDVVPTMAQGVIEYKEKYG---FDPFVS
SNIQYFLDRFYTNRISFRMLINQHT---LLFGGVTN--PAHPKHIGSIDPTCNVADVVE---DAFAT-AKMLCEQYYQAA
PDLEIEEFN-AKAPGKPIQVVYVPSHLFHMLFELFKNSMRATVELHE-GKCESYPSIKALVTLGKEDLSIK------ISD
KGGGVPLRKIDRLFNYMYSTAPRPSLEPSR-AVPLAGYGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLK---ALSS
ESFERLPVFNKSAWRHYKTTPEADDWSNPSSEPRDASKYKKCLTQQYNIKDKFSV
>Danio_rerio-PDK3(ENSDARP_15430)
---------------------------------------MRLYAFLLQ--------------------------------
NHLPK-IEYYSRFSPSPLSIKQFLEFGRDNACEKTSYMFLRKELPVRLANTMREVNLLPDRLLSQPSVKLVQKW-YLQSF
LELLEFENRKPEDGHALND--------------------FLETLIEIRN-RHNDVVPTMAQGVIEYKEKFG---FDPFVS
SNIQYFLDRFYTNRISFRMLINQHT---LLFGNDIN--PAHPKHIGSIDPSCNVAEVVT---DAYET-AKMVCEQYYQAA
PELKIEEFNAAKAPQKPIQAVYVPSHLFHMLFELFKNAMRATNDLHE-GSKEGLPLIKAKVTLGIEDLSVK------ISD
RGGGVALRKIDRLFNYTYSTAPTPSLDSK--RVPLAGFGHGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLK---ALSS
ESFERLPVFNKSAWRHYQGGPGADDWSNPSKEPRDTSKYK---AKTTDIKNTTSF
>Danio_rerio-PDK3(ENSDARP_110197)
---------------------------------------MKLFICLLK--------------------------------
DVTHK-IEYYSRFSPSPMSIKQFLDFGRENACEKTSYMFLRKELAVRLANTMREVTLLPDSLQIQPSVKLVESW-YSQSF
EELLKFEKRSPEDPHTLND--------------------FLEMLIKIRN-RHNDVVPTMAQGVIEYKEKFG---FDPFIS
SNVQYFLDRFYTNRISFRMLINQHT---LLFGDAAC--LAQPKHIGSIDPACNVAEVVR---DAYET-AKMLCEQYYMMA
PELKIGEFN-SKNPKKPVQAVYVPSHLFHMLFELFKNSMRATVELYE-NSSEGLPPVKAMVTLGKEDLSIK------ISD
KGGGVPLRKIDRLFNYMYSTAPTPRLDPSQPAVPLAGFGYGLPISRLYARYFQGDLNLYSVEGFGTDAVIHLK---ALSS
ESFERLPVFNKSAWRHYQTGPEADDWSNPSSDPRDASTYK---ATNLKIKSSIML
>Oryzias_latipes-PDK3(ENSORLP_9459)
---------------------------------------MRLFLSLLK--------------------------------
NAHPK-IEYYSRYSPSPLSIKQFLDFGRDNACEKTSYVFLRKELPVRLANTMREVNLLPDKLLSQPSVRLVQKW-YMQSF
VELLDYENRKPEDPHTLND--------------------FLEVLIEIRN-RHNDVVPTMAQGVIEYKEKFG---FDPFVS
SNIQYFLDRFYTNRISFRMLINQHT---LLFGNDTN--PAHPKHIGSIDPTCNVAEVVK---DAYDT-AKMLCEKYYFAA
PELKIEEFN-MKAPNKPIQVVYVPSHLFHMLFELFKNSMRATVELHE-NSAEGLPPVKTRVTLGKEDLSVK------ISD
KGGGVPLRKIDRLFNYMYSTAPTPSLEPG--AVPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLK---ALSS
ESFERLPVFNKSAWRHYKTSPEADDWSNPSKEPRDASKSI---YKANR-------
>Takifugu_rubripes-PDK3(ENSTRUP_21358)
-----------------------------KRLTRFNLHLGQVFTHVKK--------------------------------
NVNPK-IEYYSRFSPSPLSIKQFLDFGRENACEKTSYMFLRKELPVRLANTMKEVNLLPDKLLSQPSVKLVQKW-YMQSF
VELLDYENRNPEDSHTLND--------------------FLELLIEIRN-RHNDVVPTMAQGVIEYKEKFG---FDPFIS
SNVQYFLDRFYTNRISFRMLINQHT---LLFGNDTN--PAHPKHIGSIDPTCSVAEVVS---DAYDT-AKMLCEKYYLAA
PKLKIEEFN-TKAAGKPIQVVYVPSHLFHMLFELFKNSMRATVELHE-TSREGLPPVKAKVTLGKEDLSIK------ISD
RGGGVPLRKIDRLFHYMYSTAPTPSLEHG--AVPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLKRYKALSS
ESFERLPVFNKSAWRHYKTSAEADDWSNPSKEPRDASKSN---YKA---------
>Tetraodon_nigroviridis-PDK3(ENSTNIP_1...
---------------------------------------MRIFTFLLK--------------------------------
NSNPK-IEYYSKFSPSPLSIKQFLDFGRENACEKTSYMFLRKELPVRLANTMKEVNLLPDKLLGQPSVRLVQKW-YMQSF
VELLDYENRNPEDAHTLND--------------------FLELLIEIRN-RHND-VPTMAQGVIEYREKFG---FDPFIS
SNVQYFLDRFYTNRISFRMLINQHT---LLFGNDTN--PAHPKHIGSIDPTCSVAEVVN---DAYDT-AKMLCEKYYLAA
PELSIQEFN-TKAAGKPIQVVYVPSHLFHMLFELFKNSMRATVELHQ-TSGEGLPPVKAKVTLGKEDLSIK------ISD
RGGGVPLRKIDRLFHYMYSTAPTPSLEQG--AVPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLK---ALSS
ESFERLPVFNKSAWRHYTTSPEADDWSNPSKEPRDASKSN---YKANR-------
>Gasterosteus_aculeatus-PDK3(ENSGACP_3...
---------------------------------------MRIFTCLLK--------------------------------
NANPK-IEYYSRFSPSPLSIKQFLDFGRDNACEKTSYMFLRKELPVRLANTMREVNLLPDKLLSQPSVRLVQKW-YMQSF
VELLDYENRKPEDCEALND--------------------FLELLIEIRN-RHNNVVPTMAQGVIEYKEKFG---FDPFIS
SNVQYFLDRFYTNRISFRMLINQHT---LLFGDDTN--PAHPKHFGSIDPACSVAEVVS---DAYDT-AKMLCEKFYLDA
PELKIEEFN-MKAPKRPIQAVYVPSHLFHMLFELFKNSMRATVELHE-NSEQGLPPIKAKVTLGKEDLSIK------ISD
RGGGVPLRKIDRLFNYTYSTAPTPSLEPG--SVPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLK---ALSS
ESFERLPVFNKSAWRHYTTTPEADDWSNPSTEPRDASKSN---FKAKR-------
>Drosophila_melanogaster-PDK1(FBpp_111...
---------------------------------------MRLFPVRFSAASS--------------------------SM
ASLAKMLDFYSGFNPSPLSIKQFMDFG-QNACEKKSYIFLRKELPVRLANIMKEIALLPDNLLHTRSVSEVSSW-YVKSF
EDVLVYEKAEPTHDN-LQK--------------------FVADLDLIRN-RHNDVVQTMAQGVIEMKENEGG-QVDAPTE
SSIQYFLDRLYMSRISIRMLINQHT---LLFGGNP---HAGGRHIGCLDPACDLSDVVR---DAYEN-ARFLCDQYYLTS
PALEIQQHSSEPGDNLPIRTVYVPSHLYYMLFELFKNSMRAVVEHHGHDNNDTLPPLKVAICKGKEDICVK------ISD
QGGGIPRSQTDQLFKYMYSTAPQPSKSDLH-TVPLAGYGYGLPISRLYARYFHGDIVLLSCEGFGTDAIIYLK---ALSD
EANELLPIFNKTSSKFYRATVPTGDWSNQSSDMNARQLSATTPKRCDFLQDA---
>Branchiostoma_floridae-PDK1(XP_2592098)
--------------------------------------MMRLSPR---------------------------------IL
KSLPALVDHYSRFSPSPLSIQQFLDFGSKNACEKKSFTFLRQELPVRLANIMKEINLLPDTLLKMPSVELVQSW-YIQSL
TEILHFENKSPSDSAIIEN--------------------FTETLYNIRK-RHSNVVETMAQGVIELRDTHG---IDHQTD
SNIQYFLDRFYMSRISIRMLIHQH---------ET---HP--RHVGSIDPNCEVESVVL---DAYEN-AKFLCDQYYLAS
PELDLVSHNGIK-KSSPITVVYVPSHLYHMLFELFKNAMRAIVEYHGTAALD-YPKVKCQVSLGKEDLTIK------ISD
QGGGIPKSAMDVLFNYMYSTAPQPPKSGST-TAPLAGYGYGLPLSRLYAKYFQGDLQLVSQEGYGTDALIWLK---ALSS
EANELLPVFNTTSSRHYGTNIPTSDWSSPYTPRGS-QNSVRTFLTFRI-------