>Homo_sapien_NSD1
------------------------------------------------------------------MDQTCELPRRNCLL
PFSNPVNLDAPEDKDSPFGNGQSNFSEPLNGCTMQLSTVS-GTSQNAYGQDSPSCYIPLRRLQDLASMINVEYLNGSADG
SESFQDPEKSDSRAQTPIVCTSLSPGGPT---------------------------------------------------
------------------------------------------------ALAMKQEPSCNNSPELQVKVTKTIKNGFLHFE
NFTCVDDADVDSEMDPEQPVTEDESIEEIFEETQTNATCNYETKSENGVKVAMGSEQDSTPESRHGAVKSPFLPLAPQTE
TQKNKQRNEVDGSNEKAALLPAPFSLGDTNITIEEQLNSINLSFQDDPDSSTSTLGNMLELPG---TSSSSTSQELPFCQ
PKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMK--VSNRRPY-----RQYYVEAFGDPSERAWVAGKAIV
MFEGRHQFEEL---PVLRRRGKQKEKGYRHKVPQKILSKWEASVGLAEQYDVPKGSKNRKCIPGSIKLDSEEDMPFEDCT
ND-PESEHDLLLNGCLKSLAFDSEHSADEKEKPCAKSRARKSSDNPKRTSVKKGHIQFEAHK------------------
------DERRGKIPENLGLNFISGDISDTQASNELSRIANSLTGSNTAPGSFLFSSCGKN-----TAKKEFETSNGDSLL
GLPEGALISKCSREKNKPQ-------------------------------------------------------------
---RSLVCGSK-VKLCYIG-------------------------------------------------------------
--------------AGDEEKRSDSISICTTSDDGSSD--LDPIEHSSESDNSVLEIPDAFDRTENMLSM-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------QKNEKIKYSRFAATNTRVKAKQKPLISNSHTDHLMGCTKSAEPG-TETSQVNLSDLKASTLVHKPQSD
FTNDALSPKFNLSSSISSENSLIKGGAANQALLHSKS-KQPKFRSIKCKHKENPVMAEPPVINEECSLKCCSSDTK---G
SPLASISKSGKVDGLKLLNNMHEKTRDSSDIETAVVKHVLSELKELSYRSLGEDVSDSGTSKPSKPLLFSSASSQNHIPI
EPDYKFSTLLMMLKDMHDSKTKEQRLMTAQNLVSYRSPGRGDCSTNSPVGVSKVLVSGGSTHNSEKKGDGTQNSANPSPS
G-GDSALSGELSASLPGLLSDKRD---LPASGKSRSDCVTRRNCGRSKPSSKLRDAFSAQMVKNTVNRKALKTERKRKLN
QLPSVTLDAVLQGDRERG----GSLRGGAEDPSKEDPLQIMGHLTSEDG-DHFSDVHFDSKVKQSDPGKISEKGLSFEN-
--GKGPELDSVMNSEN---DELNGVNQVVPKKRWQRLNQRRTKPRKRMNRFKEKENSECAFRVLLPSDPVQEGRDEFPEH
RTP-SASILEEPLTEQNHADCLDSAGPRLNVCDKSSASIGDMEKEPGIPSLTPQAELPEPAVRSEKKRLRKPSKWLLEYT
EEYDQIFAPKKKQKKVQEQVHKVSSRCEEESLLARGRSS--AQNKQVDENSL-----------ISTKEEPPVLEREAPFL
EGPLAQSELG------GGHAELPQLTLSVPV-APEVSPRPA-------LESEELLVKTPGNYESKRQRKPTKKLLES-ND
LDPGFMPKKGDLGLSKKCYEAGHLENGITESCATSYSKDFGG--GTTKIFDK-----------------------PRKRK
RQRHAAAKMQCKKVKNDDSSKEIPG-SEGELMPHRTATSPKETVEEGVEHDPGMPASKKMQGERGGGAALKENVCQNCEK
LGE--LLLCEAQCCGAFHLECLGLTEMPRGKFICNECRTGIHTCFVCKQSGE------DVKRCLLPLCGKFYHEECVQKY
PPTVMQNKG-FRCSLHICITCHAAN------PANVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTP-
RRGCRNHEHVNVSWCFVCSE-----------------------------------------------------GGSLLCC
DSCPAAFHRECLNI-DIPEG---NWYCNDCKA---------------GKKPHYREIVWVKVGRYR-WWPAEICHPRAVPS
NIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMG--KGVDGTYKKALQEAAARFEELKAQKELRQLQED
RKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFSKRQ
YPEVEIFRTL-QRGWGLRTKTDIKK------------------GEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTL
DKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAG-TELTFNYNLECLGNG-KTVCKCGAPNCSG
FLGVRPKN------QPIATEEKSKKFKKKQQGKRRTQGEITKEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRP
AG-----------KWECPWHQCDI--CGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIRE
YVPPPVPLPPGPSTHLAEQ-STGMAAQAPKMSDKPPADTNQMLSLSKKALAGTCQRPLLP-ERPLERTDSRPQPLDK---
--VRDLAGSGTKSQSLVSSQRPLDRPPAVAGPRPQLSDKPS-PVTSPSSSPSVRS--------QPLERPLGTADPR---L
DKSIGAASPRPQSLEKTSV-------------PTGLRLPPPDRL------------------------------------
------------------------------------------------------LITSSPKPQTSDRPTD----------
------------------------------------------------------------------------KPHASLSQ
RLPPPEKVLS-------AVVQTLVAKEKALRPVDQNTQS----KNRAALVMDLIDLTPRQKERAASPHQVTPQADEKMPV
LESSSWPASKGLG----HMPRAVEK-GCVSDP-LQTSGKAAAPS-EDPWQAVKSLTQARLLSQPPAK-AFLYEPTTQASG
RASAGAEQTPGPLSQSPGLVKQAKQ----MVGGQQLPALAAKSG----QSFRSLGKAPASLPTEEK-----KLVTTEQSP
WALG--KASSRAGLWPIVAGQTLAQSCWSAGSTQTLAQTCWSLGR-----GQD--PKPEQNTLPALNQAPSSHKCAESEQ
K
>Mus_musculus_NSD1
------------------------------------------------------------------MDRTCELSRRNCLL
SFSNPVNLDASEDKDSPFGNGQSNFSEPLNGCTMQLPTAASGTSQNAYGQDSPSCYIPLRRLQDLASMINVEYLSGSADG
SESFQDPAKSDSRAQSPIVCTSLSPGGPT---------------------------------------------------
------------------------------------------------ALAMKQEPTCNNSPELQLRVTKTTKNGFLHFE
NFTGVDDADVDSEMDPEQPVTEDESIEEIFEETQTNATCNYEPKSENGVEVAMGSEQDSMPESRHGAVERPFLPLAPQTE
KQKNKQRSEVDGSNEKTALLPAPTSLGDTNVTVEEQFNSINLSFQDDPDSSPSPLGNMLEIPG---TSSPSTSQELPFCQ
PKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMK--VANRRPY-----REYYVEAFGDPSEKAWVAGKAIV
MFEGRHQFEEL---PVLRKRGKQKEKGYRHKVPQKILSKWEASVGLAEQYDVPKGSKNQKCVSSSVKLDSEEDMPFEDCT
ND-PDSEH-LLLNGCLKSLAFDSEHSADEKEKPCAKSRVRKSSDNIKRTSVKKDLVPFESRK------------------
------EERRGKIPDNLGLDFISGGVSDKQASNELSRIANSLTGSSTAPGSFLFSSSVQN-----TAKTDFETPDCDSLS
GLSESALISKHSGEKKKLQ-------------------------------------------------------------
---PGQVCSSK-VQLCYVG-------------------------------------------------------------
--------------AGDEEKRSNSVSVSTTSDDGCSD--LDPTEHNSGFQNSVLGITDAFDKTENALSV-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------HKN-ETQYSRYPVTN-RIKEKQKSLITNSHADHLMGSTKTMEPETAELSQVNLSDLKISSPIPKPQPE
FRNDGLTTKFSAPPGIRNENPLTKGGLANQTLLPLKC-RQPKFRSIKCKHKESPAVAETSATSEDLSLKCCSSDTN---G
SPLANISKSGKGEGLKLLNNMHEKTRDSSDIETAVVKHVLSELKELSYRSLSEDVSDSGTAKASKPLLFSSASSQNHIPI
EPDYKFSTLLMMLKDMHDSKTKEQRLMTAQNLASYRTPDRGDCSSGSPVGTSKVLVLGSSTPNSEKPGDSTQDSVHQSPG
G-GDSALSGELSSSLSSLASDKRE---LPACGKIRSNCIPRRNCGRAKPSSKLRETISAQMVKPSVNPKALKTERKRKFS
RLPAVTLAANRLGNKESG-SVNGPSRGGAEDPGKEEPLQQMDLLRNEDT--HFSDVHFDSKAKQSDPDKNLEKEPSFEN-
--RKGPELGSEMNTEN---DELHGVNQVVPKKRWQRLNQRRPKPGKRANRFREKENSEGAFGVLLPADAVQKAREDYLEQ
RAP-PTSKPEDSAADPNHGSHSESVAPRLNVCEKSSVGMGDVEKETGIPSLMPQTKLPEPAIRSEKKRLRKPSKWLLEYT
EEYDQIFAPKKKQKKVQEQVHKVSSRCEDESLLARCQPS--AQNKQVDENSL-----------ISTKEEPPVLEREAPFL
EGPLAQSDLG------VTHAELPQLTLSVPV-APEASPRPA-------LESEELLVKTPGNYESKRQRKPTKKLLES-ND
LDPGFMPKKGDLGLSRKCFEASRSGNGIVESRATSHLKEFSG--GTTKIFDK-----------------------PRKRK
RQRLVTARVHYKKVKKEDLTKDTPS-SEGELLIHRTAASPKEILEEGVEHDPGMSASKKLQVERGGGAALKENVCQNCEK
LGE--LLLCEAQCCGAFHLECLGLPEMPRGKFICNECHTGIHTCFVCKQSGE------DVKRCLLPLCGKFYHEECVQKY
PPTVTQNKG-FRCPLHICITCHAAN------PANVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTP-
RRGCRNHEHVNVSWCFVCSE-----------------------------------------------------GGSLLCC
DSCPAAFHRECLNI-DIPEG---NWYCNDCKA---------------GKKPHYREIVWVKVGRYR-WWPAEICHPRAVPS
NIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMG--KGVDGTYKKALQEAAARFEELKAQKELRQLQED
RKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGVRCQNQCFSKRQ
YPDVEIFRTL-QRGWGLRTKTDIKK------------------GEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTL
DKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAG-TELTFNYNLECLGNG-KTVCKCGAPNCSG
FLGVRPKN------QPIVTEEKSRKFKRKPHGKRRSQGEVTKEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRP
AG-----------KWECPWHQCDV--CGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIRE
YVPPTATSPPSPGTQPKEQ-SSEMATQGPKKSDQPPTDATQLLPLSKKALTGSCQRPLLP-ERPPERTDSSSHLLDR---
--IRDLAGSGTKSQSLVSSQRPQDRPPAKEGPRPQPPDRAS-PMTRPSSSPSVSS--------LPLERPLRMTDSR---L
DKSIGAASPKSQAVEKTPA-------------STGLRLSSPDRL------------------------------------
------------------------------------------------------LTTNSPKPQISDRPPE----------
------------------------------------------------------------------------KSHASLTQ
RLPPPEKVLS-------AVVQSLVAKEKALRPVDQNTQS----KHRPAVVMDLIDLTPRQKERAASPQEVTPQADEKTAM
LESSSWPSSKGLG----HIPRATEK-ISVSES-LQPSGKVAAPS-EHPWQAVKSLTHARFLSPPSAK-AFLYESATQASG
RTPVGAEQTPGPPSPAPGLVKQVKQ----LSRG-----LTAKSG----QSFRSLGKISASLPNEEK-----KLTTTEQSP
WGLG--KASPGAGLWPIVAGQTLAQACWSAGGTQTLAQTCWSLGR-----GQD--PKPE-NAIQALNQAPSSRKCADSEK
K
>Callithrix_jacchus_NSD1
------------------------------------------------------------------MDQTCELPRRNCLL
PFSNPVILDAPEDKDSPFGNGQSNFSEPLNGCTMQLSTVS-GTSQNAYGQDSPSCYIPLRRLQDLASMINVEYLNGSADG
SESFQDPEKSHSRAQTPIVCTSLSPGGPT---------------------------------------------------
------------------------------------------------TLAMKQEPSCNNSPELQVKVTKTIKNGFLHFE
NITCLDDADVDSEMDPEQPVTEEESIEEIFEETQTNATCNYETKSENGVKVAMGSEQDSTPESRHGAVKSPFLPLAPQTE
TQKNKQRNEVDGSNEKAALLPAPFSLGDTNVTIEEQLNSINLSFQDDPDSCTSTLGNMLELPG---TSSSSTSQELPFCQ
PKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMK--VSNRRPY-----RQYYVEAFGDPSERAWVAGKAIV
MFEGRHQFEEL---PVLRRRGKQKEKGYRHKVPQKILSKWEASVGLAEQYDVPKGSKNRKCIPGSIKLDSEEDMPFEDCT
ND-PESEHDLLLNGCLKSLAFDSEHSADEKEKPCAKSRARKSSDNPKRTSVKKGHIQFETRK------------------
------DERRGKIPENLGLNFLSGDVSDTQASNELSRIANSLTGSNTAPGGFLFSSCGKN-----TAKKEFETSNGDSLL
GLPEGALISKCSREKNKPQ-------------------------------------------------------------
---RSLMCGSK-VKLCYIG-------------------------------------------------------------
--------------AGDEEKRSDSISICTTSDDGSSD--LDPIEHSSESDNSVLEITDAFDRTENMLSM-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------QKNEKIKYSRFAATNTRVKTKQKPLINNSHTDHLMNCTKSAEPG-TEMSQVNLADLKASTLVHKPQSD
FTNGDLAPKFNMSSNISSENLLIKGGAANQALLHSKS-KQPKFRSIKCKHKENPVMVESSVINKECSLKCCSSDNK---G
SPLASISKSGKVDGLKLLNNMHEKTRDSNVIETAVVNHVLSELKELSYRSLGEDVSDSGTSKPSKPLLFSSASSQNHIPI
EPDYKFSTLLMMLKDMHDSKTKEQQLMTAQNLVPYRSPGHGECSANSPVGASKVLVSGGSTHNSEKKGDCTQNSANPSPS
G-GDSALSGELSASLPGLVSDRRD---LPTSGKSRSNCVTRRNCGRSKPSSKLRDAFSAKMGKNAVNRKALKTERKRKLN
QLPSVTLDAALQGDREHG----GSLRGGMEDCSKEEPLQIMDHLTSEDG-DRFSDVHFDNNIKQSDPDKISEKGPSFEN-
--GKGPELDSEMNSEN---DELSGVNQVVPKKRWQRLNQRRTKPRKRINRFKEKENSECAFGVLLPSDPVQEGRSEFPEH
RTP-SANILEEPLTDQNHADCLDSVRPRLNVCDKSSASIGDMEKEPGIPSLTPQAELPEPAVRSEKKRLRKPSKWLLEYT
EEYDQIFAPKKKQKKVQEQVHKVSSRCEEESLLARGRSS--AQNKQVDENSL-----------ISTKEEPPVLEREAPFL
EGPLAQSELG------GGHAELPQLTLSVPV-APEVSPRPA-------LESEELLVKTPGNYESKRQRKPTKKLLES-ND
LDPGFMPKKGDLGLSKKCYEAGHLGSGITESCTTSYSKDFGG--GTTKIFDK-----------------------PRKRK
RQRHAAAKMQCKKVKNDDSSKEISS-SEGELMPHRTAASPKETLEEGVEHDPGMPASKKMQGERGGGAALKENVCQNCEK
LGE--LLLCEAQCCGAFHLECLGLTEMPRGKFICNECHTGIHTCFVCKQSGE------DVKRCLLPLCGKFYHEECVQKY
PPTVMQNKG-FRCSLHICITCHAAN------PANVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTP-
RRGCRNHEHVNVSWCFVCSE-----------------------------------------------------GGSLLCC
DSCPAAFHRECLNI-DIPEG---NWYCNDCKA---------------GKKPHYREIVWVKVGRYR-WWPAEICHPRAVPS
NIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMG--KGVDGTYKKALQEAAARFEELKAQKELRQLQED
RKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFSKRQ
YPEVEIFRTL-QRGWGLRTKTDIKK------------------GEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTL
DKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAG-TELTFNYNLECLGNG-KTVCKCGAPNCSG
FLGVRPKN------QPIATEEKSKKFKKKQQGKRRSQGEITKEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRP
AG-----------KWECPWHQCDI--CGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIRE
YVPPPVPLPPGPSTHLAEQ-SSGTAAQAPKMSDKPPADTNQTLSLSKKALAGTCQRPLLP-ERPLERTDSRPQPLDK---
--VRDLAGSGTKSQSLVSSQRPLDRPPAVAGPRPQLYDKLT-PVTSRSSSPSVRS--------QSLERPLGKADPR---L
DKSIGAASSRPQSLEKTPV-------------PTGLRLPPSDRL------------------------------------
------------------------------------------------------LITSSPKTQTSDKPPD----------
------------------------------------------------------------------------KPSATLSQ
RLPPPEKVLS-------AVVQTLVAKEKALRPVDQNTQS----KNRAALVMDLIDLTPRQKERAASPHEVTPQADEKIPV
LESSSWPASKGLG----HIPRAVEK-GSMSNP-LQTPGKA-----EDPWQAVKSLTQARLLSQPPAK-AFLYEPTTQASG
RAPAGTEQTPGPLSQAPGLMKQMKQ----MVGGQQLPALAAKSG----QSFRSLGKAPASLPTEEK-----KLVTTEQSP
WALG--KASTRAGLWPLVAGQTLAQSCWSAGSTQTLAQTCWSLGR-----GQD--PKPEQNTLPALNQAPSSHKCAESEQ
K
>Rattus_norvegicus_NSD1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------------------MCH
PKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMK--VANRRPY-----REYYVEAFGDPSEKAWVAGKAIV
MFEGRHQFEEL---PVLRKRGKQKEKGYRHKVPQKILSKWEASVGLAEQCDVPRGPKTQKCVPSSAKLDSEEDMPFEDCA
ND-PDSEHDLLLNGCLKSLAFDSEHSADEKEKPCAKSRVRKSSDNIKRTSVKKGLMPFEAQK------------------
------EERRGKSPENLGLDFLSGGVSDKQASNELSRIANSLTGSSAAPGQFLFSSCGQN-----TAKTDFETPNCDSLS
GLSESALISKHSGEKKKLQ-------------------------------------------------------------
---PGQVCSSK-VQLCYVG-------------------------------------------------------------
--------------AGDEEKRSDSVSVCTTSDDGSSD--LDPTEHNSEFHKSVLEVTDALDKTENALSM-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------HKN-ETKYSRYPATN-RVKEKQKSLITNSHTDHLMDSTKTVEPGTAEISQVNLSDLKISSPIPKPQPE
FRNDGLTTKFNAPPGIRNENSLTKGGLANQTLLPLKC-RQPKFRSIKCKHKESPTAAETSATSEDLSLKCCSSDTN---G
SPMTSISKSGKGEGLKLLNNMHEKTRDSSDIETAVVKHVLSELKELSYRSLSEDVSDSGTSKSSKPLLFSSASSQNHIPI
EPDYKFSTLLMMLKDMHDSKTKEQRLMTAQNVASYRTPDRGDCSSGSPVGTSKVLVLGGSTHNSEKPGDSTQDSVRLSPG
G-GDSALSGELSSSLSVLPSDKRD---LPACGKIRSNCIPRRNCGRAKLSPKLRVTISTQMAKPSVNPKALKTERKRKLS
RLPAVTLAANGLGNKESGGSVNGPLKGGAQDPAKEEPLQQMDLLRNE-------ETHFDSKVKQSDPDKILEKEPSFEN-
--RKGPEVGSEINIEN---DEPHGVDQVVPKKRWQRLNQRRPKPGKRASRFREKENSEGAFGVLLPGDPVQKGRDDYLEQ
RAP-PTSILEDSAADPNHVSHSESVGPRLNVCDKSSVSMGDLEKETGIPSLTPQTKIPEPAVRSEKKRLRKPSKWLLEYT
EEYDQIFAPKKKQKKVQEQVHKVSSRCEDESLLARCRSS--AQNKQVDENSL-----------ISTKEEPPVLEREAPFL
EGPLVQSDLG------VAHAELPQLTLSVPV-APEVSPRPT-------LESEELLVKTPGNYEGKRQRKPTKKLLES-ND
LDPGFMPKKGDLGLSRKCCESGHLENGVGDSRATPHLKEFGG--GTTRIFDK-----------------------PRKRK
RQRHGTARVHYKRVKKEDSARETPSSAEGELMIHRTAASPKEILEEGIEHDPGMSASKRLQGERGGGAALKENVCQNCEK
LGE--LLLCEAQCCGAFHLECLGLTEMPRGKFICNECRTGIHTCFVCKQSGE------DVKRCLLPLCGKFYHEECVQKY
PPTVVQNKG-FRCPLHICITCHAAN------PANVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTP-
RRGCRNHEHVNVSWCFVCSE-----------------------------------------------------GGSLLCC
DSCPAAFHRECLNI-DIPEG---NWYCNDCKA---------------GKKPHYREIVWVKVGRYR-WWPAEICHPRAVPS
NIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMG--KGVDGTYKKALQEAAARFEELKAQKELRQLQED
RKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFSKRQ
YPDVEIFRTL-QRGWGLRTKTDIKK------------------GEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTL
DKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAG-TELTFNYNLECLGNG-KTVCKCGAPNCSG
FLGVRPKN------QPIVTEEKSRKFKRKPHGKRRSQGEVTKEREDECFSCGDGGQLVSCKKPGCPKVYHADCLNLTKRP
AG-----------KWECPWHQCDV--CGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIRE
YVPPTATLSPSPGTQQTEQ-SSEMGTQGPKKSDQPPTDATQMLSLSKKAVTGTCQRPLLP-ERPPERTDSSSHLLDR---
--IRDLAGSGTKSQSLVSSQRPQDRPPAKEGPRPQPPDRAS-PVTRPSSSPSVSS--------LPLERPLRMTEPR---L
DKSIGAASPKSQAVEKPPA-------------PTGLRLSSPDRL------------------------------------
------------------------------------------------------LNTNSPKPQISDRPPD----------
------------------------------------------------------------------------KSHASLTQ
RLPPPEKVLS-------AVVQSLVAKEKALRPVDQNTQA----KHRAAVVMDLIDLTPRQKERAASPQEVTAQADEKTPV
LESSSRPTSRGLG----HVPRAVEK-GGVSDP-LQPPGKSAAPS-EHPWQAVKSLTHARFLSPPSAK-AFLYESAIQASG
RAPVGSEQTPGPPSPAPGLLKQVKQ----LSRG-----LTAKSG----QSFRSLGKISASLPNEEK-----KLTTTEQSP
WGLG--KASPGAGLWPIVAGQTLAQACWSSGGTQTLAQNCWSLGR-----GQD--PKPEQNAIQALNQAPSSRKCAESEQ
K
>Equus_caballus_NSD1
------------------------------------------------------------------MDQTCELPRRNCLL
PFTNPVNLDAPEDKDSPFGNGQSNFSEPLNGCTMQLSTAS-GTSQNAYGQDSPSCYIPLRRLQDLASMINVEYLNGSTDG
SESFQDPEKSDSRAQSPIVCTSLSPGGPT---------------------------------------------------
------------------------------------------------ALAMKQEPSCNNSPELQVKVTKTIKNGFLHFE
NFTCVDDADVDSEMDPEQPVTEDESIEEIFEETQTNATCNYEPKSENGVDVAMGNEQDSTPESRHGAVKPPFLPLAPQTE
TQKNKQRNEVDGSNEKAALLPAPFSLGDTNVTVEEQLNSINLSFQDDPDSSTSTLGNMLELPG---TSSS-TSQELPF--
--------------------------------------------------------------------------------
-------------------------------VPQKILSKWEASVGLAEQYDVPKGSKNRKCVTSSIKLDSEEDMPFEDCT
ND-PESEHDLLLNGCLKSLAFDSEHSGDEKEKPCAKSRARKSSDNPKRTSVKKGHMQFEAHK------------------
------EERRGKIPENLGLNFVSGDVSDKQASNELSRIANSLTGSSTAPGSFLFSSCAKN-----TAKKEFETSNCDSLL
GLSEGALISKRSGEKKKLQ-------------------------------------------------------------
---RGLVCSSK-VQLCYIG-------------------------------------------------------------
--------------AGDEEKRSDSVSICTTSDDGSSD--LDPIDHSSESDNSVLEITDAFDRTESMLSV-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------QKDEKIKYSRYPATNTKVKAKQKSLITNSHTDHFTDCTKTAEPG-TETSQVNLSDLKVSTLVRKTQSD
FRNDSLSPKFNTPSSISTENSLMKGGATNQTLLHSKS-KPPKIRSIKCKHKENPVVLEPLITNEDCSLKCCSSDIK---G
SPLTSISKSGKVDGLKLLSNMHEKTRDSSDIETAVVKHVLSELKELSYRSLSEDVSDSGTSKPSKPLLFSSAPGQNHIPI
EPDYKFSTLLMMLKDMHDSKTKEQRLMTAQNLVSYRSPGVGDCSTSSPVGASKVLVSGGPTQNLEKNEDGTQDPIRPSPS
G-GDSTLSGELSASLPGLMSDRRD---LPASGKSRSNCVTRRNCGRSKPSAKLRDGFSAQMGKNTVNRKALKTERKRKLN
RLPAVTLEAALQGDRESGGSEKGSSRGGAEDPGKEEPLQLMGHLTNEDG-AHFSDVRFDNKVNQSDPDKIPEKGSSFEN-
--RKGPELDSEMNSEN---DEPNGINQVVPKKRWQRLNQRRTKPRKRTNRFREKENSEGAFGVLLPADPVKKR-DEFPEH
RPPPSTNTLEDALTDPSHDGRLDSIGPCLNVCDKSNASIVGMEKEPGIPSLTPQPELPEPAVRSEKKRLRKPSKWLLEYT
EEYDQIFAPKKKQKKVQEQVHKVSSRCEEESLLARCRSN--VQNKQVDENSL-----------ISTKEEPPVLEREAPFL
EGPLAQSELG------GGHAELPQLTLSVPV-APEVSPRPA-------LESEELLVKTPGNYESKRQRKPTKKLLES-ND
LDPGFMPKKGELGLSKKCYEAGRLENDITESHAASHSKEFGG--GTTKIFDK-----------------------PRKRK
RQRHATAKVHCKKVKNDDSSKETTS-SEGELMTHRTAASPKEPVEDGVENEHGMTASKKLQGERGGGAALKENVCQNCEK
LGE--LLLCEAQCCGAFHLECLGLNEMPRGKFICNECRTGIHTCFVCKQSGE------DVKRCLLPLCGKFYHEECVQKY
PPTVMQNKG-FRCSLHICITCHAAN------PASVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTP-
RRGCRNHEHVNVSWCFVCSE-----------------------------------------------------GGSLLCC
DSCPAAFHRECLNI-DIPEG---NWYCNDCKA---------------GKKPHYREIVWVKVGRYR-WWPAEICHPRAVPS
NIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMG--KGVDGTYKKALQEAAARFEELKAQKELRQLQED
RKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFTKRQ
YPEVEIFRTL-QRGWGLRTKTDIKK------------------GEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTL
DKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAG-TELTFNYNLECLGNG-KTVCKCGAPNCSG
FLGVRPKN------QPIATEEKSKRFKKKQQGKRRTQGEITKEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRP
AG-----------KWECPWHQCDI--CGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIRE
YVPPPVPLPPGPSTHLADQ-SSGVAAQGPKMSDKPPADTNQMLSLSKKALAGTCQRPPLP-ERLPDRTDSRPLTIDR---
--VRDLAGSGTKPQSLVSSQKPLDRPPAVAGPRPQLSDKPS-PVTGPSSSTSVRS--------LPLERPLGTAEPR---L
DKSIGAASPRPQSVEKTPV-------------PSGLRLPPPDRL------------------------------------
------------------------------------------------------LVTSSPKPQTPDRLPD----------
------------------------------------------------------------------------KSHGSLSQ
RLPPPDTILS-------AVVQTLVAKEKALRPVDQNTQS----KNRAALVMDLIDLTPRQKERAASPHEVTPQADEKLPV
LESSSWPASKGLG----QIPRAVER-GSLSDSVLQPPGKAAAPL-EHSWQAVKSLTQARLLSQPSAK-AFLYEPATQASG
RAPPGAEQTPGPPSQVPGLVKQVKQ----MVGGQQLPGLTARSG----QSFRPLGKAPSSLSTEEK-----KLATTEQSP
WALA--KSSPGPGLWPMVAGQTLAQSCWSTGSTQTLAQTCWSLGR-----GQD--PKPEQNTLSALNQGPSSHKCAESQQ
K
>Monodelphis_domestica_NSD1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------MIELPG---TSSSSTSQELQFCQ
PKKKPAPLKYGVGQLVWAKFNRRPWWPSRICCDPLINTHSKMK--VSSQRPY-----RQYYVEALGDPSEKAWVAGKSIV
LFEGRHQFEEL---PVLRRRGKQKEKGYRHKVPKKILSKWEASVGLAEQRDVPKDFKVRKRIRTSAKLDSEEDMPFEDCT
ND-PESEHERVLNGCLKSLAFDSETSSDEKVKPCTKSRVRKRSTSLKRTSIKKSSSAFESHK------------------
------EERREKITETLGLNYISSDVSDKQASTELCRIASSLSAASNTTTNYLFSSCGKT-----TTKKEFETSNCDSLL
GLSESVLISSSSVEIKKPL-------------------------------------------------------------
---RSMVHSAKPSRLCYIS-------------------------------------------------------------
--------------AGDEEKRSDSASLWTTSDEESSDSDLDLIDQSSESDGSALEISGSFEKNESESPM-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------EKNEKVQYSRYRTKNSRVKARKRSRKTSSHLDHLLDCTKAPEPG-SEESQGADSDSKMPIIAR-----
--NDNLSTKYTMPQSISHENSFVKSGLTNQPLLQSKHNKQPKARSIKCKHKESPTAEQPSVLDEDFSLKCCSSDSK---G
SPLDCVVNSGKLDSLKLLSNMHEKPRDPAEIETVVVKHVLSELKELSYRSLNDDLNDSGSSKINKPLLFPSSSGPTCLPI
EPNYKFSTLLMMLKDMHDSKTKEQQLMTTQNVVSYRSPGLGDCSSSSAAGGSKSLVSGGLTHKTEKNGNCIQDSVCQNPG
G-SESSLTQESSGSLTGLLSKKRR---LTASSRRRANSITRRNCARSKSS-KLQDGFLAQMGKDTIESKDLKSEKKRKLN
QPPNMTIETALGECKEAPTSVNKSLSSGPADSKRKQSLQLMEHLTGEDC-AHFSDVHFDPMIKKPETDKNPEKCPSFEN-
--GEVLELDSEMNSESSLSDESNDVNHVAPKKRWQRFNQSRAKTSKRISRSSREKNSKSAFGGLHPCDFLLEG-NEGPED
RPSSPSKVLEE-EKKQKCEGHLDIVVPQLNVCDKPNSD--GLPRESGLSNFPPQPELNT----QEKKRLRKPSKWLLEYT
EKYDQIFAPKKKQKKVQEQLPKVSSLKENEVQTTQCQPSTDLQNKPVEESS-------------STKEDPPVLEREAPFL
EGPIGQSELG------GGNAELPELTLSVPI-TREVSSWSS-------LDSEEPSLK-PRNYESKRQRKPTKKLLES-ND
LDPGFMPKKGDLTLLRKVWVV--------------------------FVFEK-----------------------QRKRK
RQRHVAA--HCKKVRNEDSSREAQN-SEGEPITPGTTASPKDSIEESVEHDHGMPVSKKMQAERGGGAALKENVCQNCEK
VGE--LLLCEAQCCGAFHLECIGLTEMPKGKFICKECRTGILCTENAHYYGE------DVKRCLLPLCGKFT????????
??????--G-FRCSLHMCITCHAAN------PASLSASKGRLMRCVRCPVAYHANDFCLAAGSKVLASNSIICPNHFAP-
RRGCRNHEHVNVSWCFVCSE-----------------------------------------------------GGSLLCC
DSCPAAFHRECLNI-DIPEG---NWYCNDCKA---------------GKKPHYREVVWVKVGRYR-WWPAEICHPRAIPS
NIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMG--KGVDGTYKKALQEAAVRFEELKAQKELRQLQED
RKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKASDENPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFSKRQ
YPEVEIFRTL-QRGWGLRTKTDIKK------------------GEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTL
DKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAG-TELTFNYNLECLGNG-KTVCKCGAPNCSG
FLGVRPKN------HPNPTEEKSKKLKRRQQVKRRSQGEITKEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRP
AG-----------KWECPWHQCDV--CGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIRE
YVPPPVPLTSGANTHLAEQ-PSEIPAQRPLMVDKAPGAMGQRLQLSEKTLVGTCQRPQLS-DKPLVMPDSTPQSPDK---
--SPGVSGP--RPQPLEVGQRPADTSLVVTSPRPQLSDKSSQALSGSKSPPSVRSSVAAGLRSQLLDRPLALAGPKPQSL
DKSLSTISSKSQQPDRPVV-------------TTGPRLQPSDKS------------------------------------
------------------------------------------------------PITNGPKPQTSDKP------------
--------------------------------------------------------------------------LVPLGQ
RLPPSEKVLS-------AVVQNLVSNEKALRPVDQNTRP----KDRATMVLELS---PRQKERAASPHEITPQPTEKLPV
LEQSPWPVNKALG----QMPRAAEK-VHPSEAVLQASGRASAPV-EHTWQAGKTLIQARLIPRPPAK-GYLFEQAPRAAG
RVPVSMEQSSGSFGKA---LASGEP----MAGSPQSPGLATKATPLMVQSPRPPVKSPDLGPPAEK-----RLAMTEHPP
WALG--KSPAGPG--PSGADQSLAQTCRSPGSPQTLAQTCRPLGKGLN-KGPD--PKPEQSAVPALNQTPSNHEPAESKQ
K
>Gallus_gallus_NSD1
------------------------------------------------------------------MEQACEVSRRSCLV
PFG--TSLPAAEPKGGPFGEPRG----------PEPPAMQLAAAKPGFGQDPSSCYIPLRRLQDLASMISAEYLGGPADG
AEALPDPGSPPPRAPA----------------------------------------------------------------
----------------------------------------------------PQEPPGGAGPE-----------------
-------------------------------------------------------------------------PAALGFP
LLLRDGGDDEEEEEEEEEEDDDDDEEDDDDDDDEEPEHSRGAGSPEPPRLQPAELPGSDGGPGEDAEPSGSAAAALQLIR
AKKKPTPVKYEVGDLVWAKFNRRPWWPCTICHDAVLDCHSKMK--VSNRRPY-----REYYVDPLGEPSEKAWVAGKAIV
LFEGRHQFEEL---PVLRRRGKQKEKGYKHKVPQRFMAKWEVSVGQAEDM-LLGGPEDQKCSQNSSELDSEKEVQSEYYS
NGPGAK-KDRQLNGCFKSLAFDSKHSANEKGKSHIKPHMKKSSESRKRTRVKKSGMREEASK------------------
------GEIQEETPESIVNNMIVGDLPEKHASHELRRIAKSITASNSTRENHLLSSFGERRFENITLKSDYGSHKSDALK
NTLQGDLFSNASLEREKSS-------------------------------------------------------------
---LGILCSSK-LQIHYSAS------------------------------------------------------------
-------------EAGVEKKQTESDSSSSLSDGGNSD--VDTMDQSSERASSTLEVSDSSDKMEKEFPM-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------TSSGNIKLSMYFSQKSSRRARKKSYRDRKPLGGLVTSRLDAEFA-HRELEGGSSDAEMSLTALECSSD
VRNDNLSLANKHATPQSVSKDSSWSAVANQTTLKLKNMKLPRIRSIKCKHKEKVAGLEPSLAEEESGMNHCSSDTKGFSG
LQRDSLQRSGKADGQKLLNNVHEKPRDSAEIETAVVKHVLSELKELSYRSMNDDVGDSGTPKATVPLLFSSASGHGRLPI
EPNYRFSTLLMMLKDIHDSKAKEQQLMTGQNIVPYRNTGTADGSGGNSASSLTSLSIVGPPFKIEKNGDCAQETVSPNSS
SISNSSFSRNPPAKLPGSGTGKREPANAAVSGTNGTNCVPKRNCSKSKQSTKLGD-------KTVSNRKDLKPGGPSKF-
-LSRLSRDSGEHAFRVHG-SVASPLGNEAEDTERKESVDLTEHSTDEDS-ACLSDDNLGRIGRRPEAGRNTERCASAEN-
--GESPDLDSEANSESSLGDEANDVNHVAPKKRWQRFNQSSARSNKHISRSREKGNLESAF--GLNSHGFSLKGNECLGR
RHSPHSKVLEADLTVQDYENHLDLVEKRLNVCGKPNNSVMDSETKLGNFAPQSEF---SAQVHSERKRLRKPSKRLLEYA
EEYDHLFAPKKKSRKSQEQLRKVNSVARS-GFEGGLPAQR-SPDRETQRGPSPLVSTP-----FSTKESPPILEAECSFS
-ELEPHASDP-SEQLIEGQSDFPELVLSSSD-VSEVSASP---------DAEERFLK-SGNFESKRQRKPTKKLLES-ND
LDTAFMPKKEEWTPPKKG--TGPSESDSLELYSPAHFPDLG-EAS-EKLLEK-----------------------QRKRK
RPRHSSAAVHSKKEKNGERLGETPR-SEGETLVHGTSTSPKGGHEDGSENDHGVPSSKKIQGERGGGAALKENVCQICEK
PGE--LLLCEAQCCGAFHLQCLGLSEMPTGKFICNECSTGVHTCFVCKNCGQ------DVKRCLLPLCGKYYHEECIQKY
PPTVTQNKG-FRCSLHICMTCHAAN------PTNISASKGRLMRCVRCPVAYHSNDFCLAAGSVVLASNSIICPNHFTA-
RRGCRNHEHVNVSWCFVCSE-----------------------------------------------------GGSLLCC
ESCPAAFHRECLNI-EMPEG---SWYCNDCKA---------------GKKPHYKEVVWVKVGRYR-WWPAEICHPRTIPV
NIQKMKHDIGEFPVLFFGSKDYLWTHQARVFPYMEGDVSSKDKMG--KGVDGIYKKALHEAAVRFEELKAQKELRQLQED
KKNDKKPPPYKHIKVNRPVGKVQIFTADLSEIPRCNCKPTDENPCGLDSECINRMLLYECHPLVCPAGERCQNQCFSKRQ
YPEVQIFRTL-ARGWGLQAKTDIRK------------------GEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTL
DKDRIIDAGPKGNYARFMNHCCQPNCETQKWCVNGDTRVGLFAIVNIKAG-TELTFNYNLECLGNG-KTVCKCGAPNCSG
FLGVRPKS------QPTLSEEKSKKLKRRPQMKRRSQAEVMKEREDECFSCGDGGQLVSCKKAGCPKVYHADCLNLTKRP
AG-----------KWECPWHQCDM--CGKEAASFCEMCPRSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIRE
YVPPMGALTNGDDTQPPEQ-PPADTDPSIQPLDRLPQSVAFKLQSPEKPP-ATLALRLPPSEKPPTTLALRVQPSNKPPT
TLALRLPPPDKPPAALALRLPPSNKPPTTLSLRLKPSNKPP-TTLSLRLQPSDKPPTTLSLRLQPSDRPQAALSLRLQP-
EKQPVILALKPQQPDKPPTNAVLWPLDESSGDASEPHLPSKSPPGTPHSLDGSLVPAGALLQLSDEPPAIAEVLELSDKS
LIDTETQEIELLDEFPAKCLHPQLSDRLLATAGTLQSQPVDEPPVAEQPQLLSKASAQSPQPQPAEKSPSSAIPHIPASE
EILSPDVEVLWPLPIENVPTSPVSRILPMEKAPGLGVLRLPPPEKASFSGAVRVSAVEKAPSSGALHAFAPEKAPASGMP
RILPSDKGPSLGVSWPLSLEKAHGSRSPHILPTDKALGSGALRIPLMQKVLSPGVLRPLPLEKAADAGALRPLPLEKALG
SGVARPQLLERPPSLTATWPQASDKLAAAVAPRPQALDKPPAASAPRLLLSEKALRPVDQNAQPKERGAPAAELSPQQKE
RTMLAGEQISWSAGKAVAHVGQVPWPTEKLQTHEQSHWPTAKALTPAEQSPRTAEKL--PEPTLQPSWEVASVP-AEQTP
WTSERLRVFEQTPRPAREAPVPQEQTQWIVTNIQTIEQISWLSGKVHIPRGQD--PLPEQNTALAHNQDSVCHELADSEP
K
>Anolis_carolinensis_NSD1
--------------------------------------------------------------------------------
---------------------------------MDSEASFFSAAEEHPGED-------IKFLMEKRAAAICNTKAEPQSR
AERIQETQQRAPVKMR----------------------------------------------------------------
----------------------------------------------------HNEMVSGLFPT-----------------
-------------------------------------------------------------------------PVLP---
--ERIQSNSAVGSRHEKVCMYPMYLPGNTERKKEKPCNVTKVSEKEDPGQSPATL-GNLIERLEASVTSKSPATRMPAGQ
NKKKPAPVKYEAGDLVWAKFNRRPWWPCKICHDPILDTHSKMK--VSNRRPH-----RQYCVETLGDPSERAWVVGKAIV
VFEGRHQFEEL---PVLRRKGKQKEKDYRHKVPKRFMAKWEISVGLTSEY-LKQN-GTQKCIQTSSKMDSEKETRLMGSH
EKVSLNEQNMQLNGCLKSFALDSKHFAHDKEKIVTKSRTKKSSDTRKRNRVRKSSTKLETSK------------------
------KEYGEKVPVDNVKDMVATNVPDKQASHELCRIAKSLMGSKGTVENYLLSSFGERQFENKTKKPEHEFSHRNSQQ
ERPK------VSVKKKKNL-------------------------------------------------------------
---TGLIYTSK-LQQHYSTT------------------------------------------------------------
-------------DAGVERKQVDSDSSDTFN--------FLSLDQS-IAAASTYSVLKNGDSVNKKRKE-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------RSSR-------QKNKYSARVPKSNSRRRKTLQGSLDR--------NAHMEAGRVEFHEPSFAEEVALA
YRNDNLTFADKHTTLQSKGFTS------------QMDTKQLQFRNIKCKHKGATARTESFLKEDECSSDSCFSATKGSLG
SHLDASTKSGNVDGPKPLNSAHENSRDSAEIETAVVKHVLSELKELSYRSLNDEAKDSGPPKTTVPLLFSSIPGQNHLPV
EPDYKFSTLLMMLKDIHDSKTKEKQLMTTQNIVAYRSPNGSGSSGNNTLSDLTSLPTTGTAPKLEKK-------------
--------------------------------------------------------------------------------
--------------------------QEAECQKPKE--------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------EKKRLRKPSKRLLEYA
EEYDHIFPPKKKKR-SREPFRKASSLERSEGKQKDSTGKK-ARKKHLEKKPLDSVSSASSPSASSSKESPPVLEAERSLS
DEPDSHSMEPRSEMPVLTLSSPNALEKEDEEGEEETSAAPPVLLPVLHPQTGGQLMK-SGRFGTKRKRKPTKKLLES-ND
LDTTFIPKRE-WTSIKKCSEAGPLDTEIPEFYPTTQVLDVA-EAAPEKVPVK-----------------------QRRRK
RQRRPFTAAPHKKERSKGVVGETHS-FQRDRAANGTTGSPKEITEEGSENYPGVPSSKRMQGERGGGAALKENVCQICEK
PGE--LLLCEAQCCGAFHLECLGLSEMPKGKFICTECSTGVHTCFVCKNSGE------NVKRCLLPLCGKYYHEECIQKY
PPTVIQNKG-FRCSLHICMTCHAAN------PTNVSASKGRLMRCVRCPVAYHSNDFCLAAGTVILASNSMICPNHFTA-
RRGCRNHEHVNVSWCFVCSE-----------------------------------------------------GGSLLCC
ESCPAAFHRECLNI-DMPEG---SWYCNDCKA---------------GKKPHYKEVVWVKVGRYR-WWPAEICHPKTIPV
NIQKMKHVIGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMA--KGVDGIYKKALQEAATRFEELKAQKELRQLQED
KRNDKKPPPYKHIKVNRPIGKVQIFTADLSEIPRCNCKPADENPCGLDSECINRMLLYECHPAVCPAGNRCQNQCFTKRQ
YPEVEIFRTL-ARGWGLQAKRDIKK------------------GEFVNEYVGELIDEEECRARIRHAQEHDITNFYMLTL
DKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFAITNVKAG-TELTFNYNLECLGNG-KTVCKCGAPNCSG
FLGVRPKN------QPPASEDKSKKFKRR-HGKRKSQAGILKEREDECFSCGDGGQLVSCKRPGCPKVYHADCLSLTRRP
AG-----------KWECPWHQCDV--CRKEAASFCEMCPRSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIRE
YAPSTESAADCQNTQPSDQ-QPAATGLKSQPSERLPLTVALRLQPSDKSPSSSLALRLKSSDKPPSSVALKLQSSDKSPS
TMALKLQPSDKLPSTLALSLKPSDKLPSTLSLRLKPSDKLS-SALALRLQSSDKPLSAVALRLHPSEKSPSTVALKLQPS
EKVDSTVAQKLQPSEKLSS--------------TEVHELQPSEKSTTMEASGS----------QDEP-------------
--------------FAAEASGPQTTD--------------------------KHSTAENPGPERSDVSPS----------
---------------ANRPTSPIL-----------------------------------------------EKSPATEIP
KVH--------------MLEKVVAAESPRPQPLDRAIPVGPLPQSSGRPVPS-LSLRPQPVVKPVTPIALRSKPTEKSAT
PEGAQPQTPNRLSAVVDSWPVLSDKDSTTTGLRSQLSDRLPAPVNSRPLLSEKALRPVDQNAQPKERPSVTLEQNTQQKE
RTSVSEEQSCRPTGKFSPFVGQTTCPLENLQIHEKTPWLSTKVLPSMEQSLWTAEKLQSPEQSLCSGQEGASAPSMEQTF
WSSERLCSFEQPPWPGREAPLSSGQTSWLPRNIQTFEQISWLSGKAQTPVGQDVLPLSEQNAVLVLNQDTPGHEPTESKH
N
>Danio_rerio_NSD1
--------------------------------------------------------------------------------
----MNQSYKVAGRDGSECRGDPQDSRALDVRIGS-----CGQQSTKADQSSAMHFLNPGYKLSAPFAYNQRESTSNYSP
LRRLQDLTTMVNHADGGLQDKDFHGRNKL---------------------------------------------------
------------------------------------------------LMHSPIG-GNEFGIGLYNTTNSQGN------T
AIQDLDKNGFSPVSSDSLEHFSPISNGFLHFDSTLFDSGDSKDNDEDVKG--EVATFKDTSKKCQKRNVAKTETQSSHRL
DANKHS-------SKNTAKSDPPASPFHVPFTMMEDFDSMDDYSDSDCDLPSTENCASIFNLSKRAHSPSDSHSNPSSSP
KKKQLLSVKYSIGDVVWAKFNRRPWWPCHVTTDPQIDVHTKMK--DPSRRPC-----RLYFVRMFGEIVDQAWVPAKATF
PFEGGDQFEKL---PVLRRRGRQKEKDYKYTVPKRLIPSWKASVLEAEASLTKQLNSEPPLTLIQDVCVPITEDKAHKKN
PA----------CPKSTTLSTPSSSLLSNGLNASVKNRLKPG--------TASKKKATKKMI------------------
------QSQSIKLSETPSLFKSKSNPSSDKPSIATDPLDSPYSDIDSVPRILCSKRIDESLQVELEKELSTKTTKVQACK
KTSKNSVDKPGKKTD-----------------------------------------------------------------
--VKCLKNSKL---------------------------------------------------------------------
------------KKSTPKDKTLKATSSRLKESSSPG--------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------SSDGSFAMHSHYLPASSGLIVRALAAGEETKEKDLSHEP
NSHS--PSSEHSSQTNHELSKQNWEVKNNS----------------ESSEESVDASDSPPNPTSIKRIKKRPQKNGIH-K
DPPPKSHEESESKVNNESMFSDTSSSSIPSP-SISPMDAFQDIKELSFRSLVKEECSSGE-SPLRA--------------
DSNYKFSTFLMLLKDLHDSR----------------------EKEGKPLTLPPTSPSSLIKEE-----------------
--------------------------PSLIPVGEEP--------PNEVLCEKEFAEQSSLPGKTS---------------
------------------------------TPNNSKQSKAKLKSTVK---------------------------------
--KESQKPDVVIDSVSPLKKPISPVGLDVLDKSLPLLG---DLPKSSDVSAAVTDVCAKG-----TISKVAPKKRWKTFE
SELGKSIKPKSDQVDSTLDEVKSVSTEPNGVFKDGLQESAHSD-----------VP-NKKDAS-ENKRLRKPSKRLIECG
EEYEQIFPSKKKTKKS------------------------TESCKTGSCISNT----------TPE--QPASDQITLDAV
SSSSAEKPLD----HVVAEEQKPPADVLVPPSAPKSP---SCATSLETEPC----EKKSAPLERKRPRKSVHKVLDCAIE
GESVKIPKKGESRQHKTNPEES--GVRDLEKQEEAGPPPSSPCAVSAQS-----------------EGELRTSSPIQPDV
PSVSQIPVEGEQSSPSKPQINNEDSLISEGFAAGLNDSAFSSRDSLS--GDLSGLSTNKRSVERGGGASLKENVCQVCEK
TGE--LLLCEGQCCGAFHLQCIGLTETPKGRFICQECKMGVHTCFVCKKPDK------EVRRCMIPVCGKFYHMDCILKY
SPTVAQNRG-FRCSIHVCLSCYITN------PNNPGISKGRLTRCVRCPVAYHANDYCMAAGSVPLANNSFLCPNHFTP-
RKGCKNHEHINVSWCFVCSE-----------------------------------------------------GGSLLCC
ESCPAAFHRECLNI-EMPQG---SWFCNDCRA---------------GKKPHYKDILWVKVGRYR-WWPAEVTQPKSVPE
NISRMKHEVGEFPVHFFGSKDYVWTYQARCFPYMEGDANNKEKMG--KGADAVYKKALNEAADRFRELLKEKEMRQLQED
RKNDKKPPPYKHIKVNKQIGKVLIITADLSEIPRCNCKATDENPCGIDSECINRMLLYECHSQVCPAGERCQNQSFTKRQ
YTEVEIFRTL-SRGWGLRSISDIKK------------------GAFVNEYVGEVIDEEECRSRIKNAQDNDICNFYMLTL
DKDRIIDAGPKGNESRFMNHSCQPNCETQKWTVNGDTRVGLFALEDIPKG-VELTFNYNLECLGNG-KTVCKCGAPNCSG
FLGVRPKN------QPPSDD-KTRKLRRKVSGKRKSQSEVTKEREDECFYCGDGGQIVSCKKPGCPKVYHADCLNLSKRP
AG-----------RWECPWHQCNE--CGREAASYCEMCPNSYCEQHREGMLFISKLDGKLSCSEHDPCGPDPLEPGEIRE
YVPSTSIVG---------QAPNMSASGRITQPALP-----------------PAAPLFIPAQNR-----PAFQSQRD---
-------------------------------PYGDEVVDNILPSSSPKDIKEEDMSD-----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------GEVVFEEG---EEEEEDLELVDDEDDEEEIDCRGMGLEDEEEEEEFEDYEDDFVNVDFV
GTED--------------GDEVEGDEQETSWDELVEAEK-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Takifugu_rubripes_NSD1a
-----------------------------------------------------------MRNLNGTHTQTNPFLFLLTGS
SRDDMNQSYRPSVRVGSVYGSGQTERRPLNGLVSTSYGNQCGVVKRGSDPLSALQLPSPSAAQPAGFRNSQPKRADCYSQ
LKRVPDLNRVVIRTDSDR--RDLDSRTDF---------------------------------------------------
------------------------------------------------HCASPIS-DAEFDTPSVLLPPSPGSDDVEPLE
PLQDVNRNEFSHRGLDGLGHCSPIPNGYLHFGSTLFDSSDIKEEQHSSRG--DLAPFYHSSRSSQGQADTDADGSRA---
EKRTYKPTLFNLMSKTISELNPTLSPSALPEITMRDGWSLGEECDSDGELNSPIDPG--------LNSPTGTKST-SNSP
KKRPLPVVKYVKGDLVWAKFNRRPWWPC-HICDSDQGTHTKMK--DPSPRPC-----RVYFLETIGEILERAWVPESAIL
PFKGGHEFKDL---PVLRRRGKQKEKDYKYTIPKSLLTAWKVSVAEAEYLLPERQRNTESVLLPSVNGEERVPSPVPPEK
TH----------KLPSFTVDSRTT---HNGSPPNPHPVKTPAALHSNKNQPCKKKKKCLSDI------------------
------FGHMIGGSKETSVIKVVDQFHTTTCALTEESGDSPYADLESVPMLHRPKRAAVPPVQAAHRPVRKDHGSAQVRT
EFTDKANPSTGSSYS-----------------------------------------------------------------
--PDCLTNSLP---------------------------------------------------------------------
------------SNHLEQG--VSSSSDITSGSSKMH--------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------SAT---------FPASSGLMTRALKAEEDTDLKEATRQS
STHVRAKLSPLTPVDASTEPDVFLSSEPPS----------------GAP-------HTSPKRRARKPDKKQIRNGSLT-A
PRITESNVLPDQPVEIKAEN-VPQPVSSSSPPSVSSVDGLQDVKELMFKSLVKEESSSSDLSVFRP--------------
DANYKFSTLLMLLKDMHDTR----------------------EKDGKPLTLPPSP--VLIKEE-----------------
--------------------------PLVIPTAAGGGRGSCDGLTRGIKVETGQAERATVLRNSR---------------
------------------------------VKSKKRTKPIMSSESYNFQ-----------------------DFPTKSLI
ENPDKRHRKRRLPAKIKPVIPGLSSDLANLAYGREYVTGHADLAGPSSCPPGVSDTSANYLDKNCGPSTVAPKKRWQMVE
DDDSKSKVKRRVSLEMNGSFIASSPDLHPEEEKQGNSDSFFSE-----------TNYSTAGNA-ESKRLRKPTKRLLESA
EEYEQIFATKKKSKKS------------------------PSESSTSETSGPT----------LLHNLGAGLEAVTSTPS
HVVAVDASSE----HGPSEDEVYSVVSSVSPVKTQPPPNTDAEQEPHLAP-----KTGLLLQEQKRPRKPSQKVLECTIE
EVAVGPAKKKELKRPRGDSDQIRSEVKVLLDKAQAGSLRKEKPSSGAPS-----------------APVAASHCSESEDL
LNLTPPHHSPSPGCSDIPKPESDLEPCSAVDQQNLHSGAVTPKPEVLSTGLIDSFTSQIDIKGKIGPTSLKENVCQVCER
TGD--LLACDGHCYGAFHPQCIGLSAAPKGKFFCRECSSGVHSCFVCKTSGN------GVKRCMIPLCGKFYHNDCITAF
SATQPHNKG-LRCPLHVCLSCHINY------PHSNCS-KGRLARCVRCPVAYHANDNCMAAGSLVLANNSFLCPSHFTP-
RKGCKNHEHINVSWCFVCSE-----------------------------------------------------GGSLLCC
ESCPAAFHRECLNI-EMPQG---SWFCNDCKA---------------GKRPRFKDILWVKWGRFR-WWPAEVCLAKDVPH
NILKMKHDVGEFPVQFFGSRDFVWTYQARVFPYMEGDTHNIETMG--KGADAVYKKALSEAAERFKELQAERVMRQLQED
RKNDKKPPPYRHIKVNRAIGKVQFITADLSEIPRCNCKASDENPCGVDSECINRMLMYECHPQVCAAGERCQNQAFTKRE
YTPVEIYRTL-SCGWGLRAVSDIKK------------------GAFVIEYVGEVIDEEECRARIKHAQENDIFNFYMLTL
DKDRIIDAGPKGNQARFMNHCCQPNCETQKWTVNGDTRVGLFALQDIPKG-KELNFNYNLECLGNG-KTVCKCGAPNCSG
FLGVRPKN------QPSAEKLKLKEGKRRVSMKKKTKQEVTKEREDECFSCGDGGQIVSCKKPGCPKVYHADCLNLAKRP
AG-----------RWECPWHQCDI--CGKEAASFCEMCPSSYCKEHRDGMLFISKLDGKLSCSEHDPCGPEPLEPGEIRE
YVPNMTSVRPKNMPPAISMVPVSKSCSPAPTASLP-------------TEHRPPPRLYINTKTATSSFVPFKRSYLT---
-------------------------------DEGDEGDEKPVSAPSSSSSSTEERED-----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------GEVEDGEVCQLEVEEDDEEEEDDDEDEEDDDDDDETGEMEIVEEEELLYSGDLLEDNSK
EDTGGGNVFDDWSDYVDEEEDGEVEDDEDEWRMVVDEDK-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Takifugu_rubripes_NSD1b
--------------------------------------------------MSGPYTGPNQY----SCPLTSGADLS----
LSRCHDHRTSLTMSAVTSSLKHPPVYGFTPREHCFSSSSSSSSSSSYSPLRRLQHLTTMVSQPDLVLPLREPERSWEWGS
SQREMGPAADCTG---NVYSTTQNLRKEG---------------------------------------------------
------------------------------------------------NLGKSTGGQKAAADGK------------SQDK
EKKTEGGFSGPSSPAFSLESNSPFANGFLHFESSLFEDEDNSQEQDSSG------ESQDKQENVPHSHLSVSNSDSK---
--------------TSTFPTTKVVTRSQSSGQRRRYWDGSDDEWDSDTELFLLSDSY-------------SRHSM--NSP
KKKSLPPLKFLEGEVIWAKFNRRPWWPCEVIVDPALGNYHRVK--EPSERPC-----RLYYVRTFGEPVEVMWVEDKSTH
TFHGGFELEHL---PLLRRKGKQREQNYRCTIPKRYHNSWNSSVAEAESVLQKRPKMASSALLSIEDAFLES-SALEEAN
KD----------QTTVAPSSPPAVQETTPDTNGCISSPVLSSPTMTPAKPSTLKKSGKK---------------------
--------KPNKSSKQLKSKHSKMTFYNSFDQCDRDSEECPYSDLESVPKILCPKALERQQKIPAPIQTSVAAVKEVKKQ
PEVQSGLWFSKSGKDRRPKTISPVPDRTLFSKVPSKKKNSPVVNKKSLV--PGSSSGRGDLSGLPDKPKTPVPAETEPPS
EQAEHLKCKNGPAASRT--------FGRDSDPAEKSPIPVETVRPPHKGGPSKGRHTIGDTTHNVTCAAPDNSDTEQALK
PNTEG--ILNDESKISESVESTAHTEQSEAAKHTKPTDSNSEGPEELEADDTSGDGLDVNATEREKQARLKAKCRMPFVK
LIRKDLQ---FKNSSVTVSSSDHPECTKIKKTLDANVADAPKPSDSVDNIPSSSVGQETKSEPATVSVKKMKASGGTSIL
CLSAEPVKIILSSHISRLSDETGSPEEESIHLN-------VSPNTVAHPPPHPSPPPPPSPGKSINSSERSD-----ISG
QTSTAN--VPSQQPVTLGFTNVLSYESSKEVIHKTKRASGKVGKHVLPEQPAHLPASSRLMTRALKAMQEQEKSGKARKA
HRQQEDLVVCTSKTSTRH----PETKRDRPGKMSTHSKNNGELDEDTFSSCSTPTTLSSETADFEGNVKSEDEDLSIS-S
TPPMDFIPLTSRVKSKKEDHSSEGSSSSLSSSPFSFMNAFKNLEEVSFQSLASEA--DGKPVSFKA--------------
NKNYKFSTFLMMLKDLHDTR----------------------ERDGTPLELQIGPASAHVKKE-----------------
--------------------------PLVMPGEVPTAGKHELTEHIGDNNNLNPNK--LTQNEDR---------------
------------------------------TWLVSKRPYIRKA-------------------------------------
---NSNRIKKKANRRVPSQPSRSGPGFPGLESP----PAVDSSRVGSHIQSVLDIKSNNWERLTGSHEAVTLEETAR--W
SRVTENLENMMPLKQRTCSSALVLEQPNGLLADCNKTGPWLMR-----------NVGDGDKSRTAHKRVRKPSKRLIEWS
EEYDQIFSTRKKSKKP----LHMIGKA-VQPVTTTPDLLAMDKDTHERPSLKF----------IPEIQTPPPEEITPTQS
-ELKIPSTEN----SQ--DAPVDTVDTLTPPPETDASLPEGFIKHPG----------SAPLLGRKRKRKPTQKILEYCLE
AEASAGPKKKVKTLKSISNQSLESDADCAPPSVKSKTKLLAPSSSSLTTTEVSNLGPSQANLPPICPGPSPPVPATPKPD
HFELPSADINAPQAADVKAHVIRKDAAESEGEQSSLDHSFSSMKDELLLCDDTLSPSRKIIGDRGGPASMKENICQVCEK
TGE--LLLCEGQCCGAFHLACISLAEAPKGKFICPECKSGIHTCFVCKKRSE------DVRRCMIPVCGKFYHGECIANF
APTVAVNRG-FRCSIHVCLTCFIAN------PNSSTISKGRLVRCVRCPIAYHATDLCMAAGCVILSNNSIICPNHFTP-
RRGVKNHEHVNVSWCFVCTE-----------------------------------------------------GGSLLCC
ESCPAAFHRECLNI-EMPKG---SWYCNDCKA---------------GKKPRFKDILWVKVGRYR-WWPAEVSHPKTIPD
NILRMRHDVGEFPVHFFGSNDYLWTYQARVFPYMDVDANSKEKMG--KGVDATYKKALEEAAVRFRELQAEKELRQLQED
KKNDRKPPPYKHIKVNRPIGKVQIFTADLSEIPRCNCKATDESPCGMESECINRMLLYECHPQVCPAGERCLNQAFTKRQ
YSQVEIFRTL-SRGWGLRCVHDIKK------------------GQFVSEYVGEVIDEEECRSRIRHAQENDICNFYMLTL
DKDRIIDAGPKGNEARFMNHCCQPNCETQKWTVSGDTRVGLFALVDIPAG-TELTFNYNLECLGNG-KTVCKCGAPNCSG
FLGVRPKN------NPPSED-KGR--KRRGHGKRKKKVVVTKEREDECFSCGDGGQMVSCKKPGCPKVYHADCLNLTKRP
AG-----------RWECPWHQCDI--CGKEAASFCEMCPSSYCNKHREGLLFISKLDGKLCCSEHDPCGPEPLEPGEIRE
YKPE----TSGLGMAVIQSCASNSTASSVMPKTRTDREISAGAGT-CAPESLPAFSIPVPVTVPAGTSAGPRPPVGS---
-------------------------------DLPSSPHVFDLPHYSPISSYDEE--------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------EEELLAEVEDDEELVEEGQQKSDEEDEEAVYLEEDEEEEDDEEEE-------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Oryzias_latipes_NSD1a
--------------------------------------------------------------------------------
----MNQSYRAGLRVGSVFGSTQPELRAHN--GSTSYGNRCGVVKRGSAQATPAPLPPSSLKQTAFLGYGQPERPCCYSP
QRRP---------QHPSK--SDLHPHHNI---------------------------------------------------
------------------------------------------------HCASPIDEDDEFEAPLVQLPPSPGDDDLEPFE
TLQDGSRNGFSPGSPDSFDRCSPIPNGCLHFESTLFDSSDVKEEDEGRQGGEDLTPFHHPSNSNQDRTATKCKTTWSSGV
DRIPYKPTVFNLMSKTISELNPTLSPSALPEITLRDGWNLGEELDSDVELSS-FDPG--------LISPAGTNSN-SNSP
KKKLLPAVRYSEGDLVWAKFNRRPWWPCRVIYDPDQGFHTKMK--VPSPRPC-----RMYFLETVGEVAERAWVPNGVIL
PFEGGHQFEDL---PVLRRRGKQKEKDYKYTIPKSLLTAWKVSVAEAELLLPGRQSNSA--LSVSTGEGERIPSPVSKEK
EA----------DDPSVSLDLIQSPLPTEAPNGNEHQPLKNSSVQAKKIKTVKRKKKCLSDI------------------
------FGHIVGGSKESAAS-VGSQLNSSSRVLKEEPKDSPYADLDSVPMLHRPKRTPVSPEHDVG-AFRLKEGSPTESK
NSRVKVKQILDLSHS-----------------------------------------------------------------
--SDGLRNQLP---------------------------------------------------------------------
------------CKEGKSDHKSDGCAELLLRSDEKG--------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------TTP---------LPASNRLMRKALKAKEETDQKDALAPN
HIPTQTPPHPRTDATWTNAPIKTEMSENWD----------------SPGNVFLPINHSSPKRRTGKLEKKLVCNGSLI-K
SKRKDVSEQHFQSVKMEAESSQSEPSSASTSMSLSPEDAFPEGKELRFKSLAADN-KVTDPSVFRP--------------
NSSYKFSTFLMLLKDIHDTR----------------------EKEGNPLKIPPPP--ALIKEE-----------------
--------------------------PLVIPTSADPLTGSGDGSTLRIMSENGQSGKSSVPQSTQ---------------
------------------------------RRAKSKTQTVPAANTYQCE-----------------------DVP---LC
TQSDKQRRKQRLPSKLKVRKPCPTADLANMAHGREFVSGHTDPLDPGSDPFAAPPDSSASYLDGNSEISAAPKKRWQLVE
GADERMASD-------ASQLTGASPEAVPETEKHADSDSLS-----------------SAGQS-ENKRLRKPTKRLLEST
EEYEQMFSSKKRLKKH------------------------GSESSKMETLGMS----------TLHDFSAAEGFDTSSSV
DPAESQLEMR----PSLSQDELSPVATSASPVSPQPSFDSEAAEKTDLPLG----SDTAQIQERKRPRKLSHKVLECTIE
EVSAAPARRKEQKGLADITSDVKVLVKKTQFAAAAAAAAAGKKDPVPSA-----------------SPDSA--------V
ASKLPQRRSPTPQPCKSPKQEDETEPCSTEEKQTTHTGTLTPKPEVLPTGLNDSFSSQVDGKGKT--SSLKENVCQVCER
PGD--LLVCEGHCYGAFHLQCVGLSVAPKGKFFCQECNTGDHMCFVCKKSGD-------VKRCIIPLCGKFYHMDCILAF
SATQPHNKG-FRCPLHVCLSCHITN------PVNVFSSKGRLARCVRCPVAYHANDNCMAAGSVVLDNNTFLCPNHFTP-
RKGCKNHEHINVSWCFVCSE-----------------------------------------------------GGSLLCC
EACPAAFHRECLNI-EMPQG---SWFCNDCKA---------------GKKPRIKDILWVKWGRYR-WWPAEVCLARDVPN
NILRMKHEVGEFPVQFFGSKDFVWTYQARVFPYMEGDTHNIEKMG--KGADAIYKKALSEAAERFKELQTEREMKQLQED
RKNDKKPPPYRHIKVNRPIGKVQIITADLSEVPRCNCKASDENPCGADSECINRMLMYECHPQVCAAGERCQNQAFTKRQ
YTTVEIYRTL-SCGWGLRAVSDIKK------------------GAFVSEYVGEVIDEEECRARIRHAQEHDICNFYMLTL
DKDRVIDAGPKGNQARFMNHSCQPNCETQKWTVNGDTRVGLFALQDIAKG-EELTFNYNLECRGNG-KTVCKCGAPNCSG
FLGVRPKN------QPPAEKVKLKEGKRRVGMKKKTKQQVMKEREDECFSCGDGGQIVSCKKPGCPKVYHADCLNLAKRP
AG-----------RWECPWHQCDL--CGKEAASFCEMCPSSYCKEHREGMLFISKLDGKLSCSEHDPCGPDPLEPGEIRE
YMPSMASVRPGAVAAPVLDARRASSSSSSSSSSSPYVPISYPDSQTAASKREPPPRLYINTKTATSSFIPSSSSYLA---
-------------------------------DTTEET------TTSSSASSKDERED-----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------GEVEEGEVCALDMQEVEEDEEDEENDT----------EMLEEKEEEPIYGGDLVEDEEG
EDEDDPWG-------SCFDDDGEVEEEDFESWGKLEDEK-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Oryzias_latipes_NSD1b
--------------------------------------------------MSGPTSGPGRKSLHSTCPLTPTRDPSTHSG
PSRRHSHKVDLTMSAAASSLKHTSVYGFAQMD-----SSSTLPSSSYSPLRRLQHLTTMVSQSDLVLPLKEPESAWKWGA
QKSDRMEGDKNSWSDCRKFSGSQTMSREE---------------------------------------------------
------------------------------------------------TPAQSAYGQKQAEVQKGRSESDSVRFTDSATD
EKRTEGCFSGPPSPAFSLDSNSPFANGLLHFESSLFEDEENDEEQGTTSPIGGLRDKEQGTENASESSPRKLSSNSK---
--------------EAALPSAKVVTRSQSSGLRRRYWDGSEDEWYSDSELFLFDDSS-------------SKQSVQPNSL
KKNSLPPLKFVEDEVVWAKFNRRPWWPCEVLVDPAQGVYHKVK--EPSDRPC-----RLYHVRTFGQPEEQVWVEDKSIH
TFHGGFEFERL---LLLRRRGKQRVQNNKCTIAKRFQESWKFSVAEAEAVLPARPKMAS-ISFSMDDLCQFS-SPPETEK
KS----------QPTLTPFTLPACTLS---ETSHLTNGSLSSPITPAEKPSTLGKSSSK---------------------
--------KKSKSSKDPNSKHVKKTLHNSPKDTDRNNEECPYSDLESVPKILCPKALERQTNS-VPSQPSVMVAKELKKQ
PEVQSGLWFSKSGKDRRPKTTSPMPDRSLFSKLPSKKKNSSTVCKKTLITTPSYVSGSGDSAPLLDKNK---PAETSLVP
RKTSSLNCTNNQAGIKTSDSVEAFVDQPDLLDREKNLLSVEVVCLKARPSASKSTDSVSEPPSSKRESKDDKRDSELSKN
VDFDGQSSLFKNKKNVSETKNSVKIATKPVNDTIFDQEKKTDKTIKLCLQSKSNDSLSI----LEKQTSLVSKCRLPYVK
LIRKEIKDRRYLNSSGTVFTAGTVVCKEKEKEPNGTKTCQSQQKDSR----TSASKDHSVAEPEKGSVKKVKTIDRSGKL
HLSTDQSLGNRTEVSSVSAVDLGSKLVEEAVLNSKTRKETQSTSKQTHLPESKNNPGSAVPNKSSEQEKGSEEHISSISA
STANALPGLCEEEPLCEDYRTPESFCSGKPKKVSKKSKRVREVNEVLKAQPAHLPASNRLMTRALRAMCDPTKQDIVGKK
AEQKQILKSFRKTNHVRKNHKTKLEFYTKIKALKSHHPDKSECDQGKISSSSSPSLMFSDSSDFED-VKSEDEDLSIS-S
TPPMDFIPLTSKVKTKHEGQSSDIYSPS-PPSPFSFLRAFKNVEEVSFQSLGADR--GGKPISFKP--------------
KPNCRFSTFLMMLKDLHDTR----------------------ERDGAPLELEIGPPSAHVKKE-----------------
--------------------------PLVMPGEAASAGGDQETTCALTDSSAIPDKSVEALNEGG---------------
------------------------------ASQTPKKSSNRRT-------------------------------------
---NSGWFKSKPNRRAPCSPAKSGPGFPGLESLSEMMPAEDSLEAMEWSSRVVDFQSSSWDEPGGGSDAVGAEQQEENPW
SMAKQNLTAPLLLEQRERDTAE--EQPDCLVSDFIKRDSSFAN-----------ISGEDDKAVGAHKRVRKPSKRLIEWT
EEYEQIFGTRKKTKKP----LQLIGKASPTPVTSAPEPLDSDNNTSDRPPSTA----------LPEIQTPPPEEIAATTP
PELQIPSSQH----TKPRDTPVLSTDTLTPPPEVEPLLSEVSPKDNKEV--------SLPVLEKKRKRKPTQKILEYCLE
AEASTGPKKKIKGLRNNSSSTAHSDSAPPLLKLKSKAALTPTPTSEVTP------CPPTPSIQINHRAALPPHPAPSPPE
PRQLETAKADAPPAEDQNIPDDPKDVSEGEGDQCSPDHSFSSAKDDFGLCDDSVLPARKIIGDRGGPASMKETICQVCEK
TGE--LLLCEGQCCGAFHLACISLADAPKGKFVCPECKSGVHTCFVCKKRGE------DVRRCMIPVCGKFYHGECITNH
APTAPVNRG-FRCSIHVCLTCFIAN------PNSSSISKGRLVRCVRCPVAYHATDLCMAAGSVVLSSNSIVCPNHFTP-
RRGVKNHEHVNVSWCFVCTE-----------------------------------------------------GGSLLCC
ESCPAAFHRECLNI-EMPKG---SWYCNDCKA---------------GKKPHYKDILWVKVGRYR-WWPAEVSHPKTIPE
NIQRMRHDVGEFPVHFFGSNDYLWTYQARVFPYMDVDANSKEKMG--KGVDTTYKKALEEAAVRFRELQAEKELRQLQED
RKNDRKPPPYKHIKVNRPIGKVQIFTADLSEVPRCNCKATDESPCGSDSECINRMLLYECNPQVCPAGEKCLNQAFTKRQ
YSQVEIFRTL-SRGWGLRCVHDIKK------------------GQFVSEYVGEVIDEEECRSRIRHAQENDICNFYMLTL
DKDRIIDAGPKGNEARFMNHCCQPNCETQKWTVNGDTRVGLFALVDVKAG-TELTFNYNLECLGNG-KTVCKCGAPNCSG
FLGVRPKN------NPPSDD-KGRKMKRRGHGRRKKKVVLAKEREDECFSCGDGGQMVSCKKPGCPKVYHADCLNLTKRP
AG-----------RWECPWHQCDV--CGKEAASFCEMCPSSYCCQHRDGLLFISKLDGKLSCSEHDPCGPEPLEPGEIRE
YNPAPRALTSGLGMAVIPAAAASSSARSLRQTDRGAHEGGDGGG---AGEPFPPFSIKVPITIPVAPPAASPPHT-----
-------------------------------DTPSSP--FHLPHYSPISSYEEERDV-----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------FEEDEEELLEDSHDDGEAVMEEEEEEEEGLDYLELEEEQEEDEDEEE------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Petromyzon_marinus_NSD3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------PPHSQPTPEKASGSPEIKLKITKTYFNGKALFE
SSLCGDLVVTPE----------QPGQQQQPKESSAATAADVKQSTLLRTKGRPRKLQPVKGPPGS---------------
--------------------------------------GTSVPPVSHSVGACVLPARPVHPSTPPLPTTP----------
---PLSADLYSIGDVVWAKISGHPWWPCMVSCDPKLGIHMRVK-VGQVKSFT-----RQYHVQFFGEAAERAWVCYRSLV
MFSTREQYELLVSELAKRTSSASERTKILKPMASRVRSQWFVGVAEAEAAAALCREERN---------------------
---------------------EKFTFIYFDVKP-KDMGHHKGQTPSSSQKKKTPSQNNIIET------------------
------------KLTLNIPPRFYISFNNVEQRCHGCVDCAASHSSG----------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------SVNLDV
IFSSSHRRKLDDGSS---LTAASVSGQERDDVGNDEVRRAREHTN------------------------------GAGGG
GGLTPKKKRGISLENNVAVRSWHRSI------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------IMFARNAHSS
DGIYPATFITATSNLCLTV-------------------------------------------------------------
--------------------------------------------------------------EAESQSSLLRRPQAGESG
VEESVPRKRVRKEPKNTAAQCHTKPALCS------------------------------------GVWMVAKLSDSCKPL
KKRSRASTTDSTSPSECDEEGALPPDAEVMVTRSLIYHACSAASPAGQGEAVYQEGSEDSQSEGKRGSSKRDALCLACEK
TGGGSLVSCEGQCCGTFHVECLGVQTAPGDKVMCNECSTGLHVCFACKCAGA------EVRRCAVSSCGRFYHEECVQRS
SAAVFEGRR-FRCPLHVCLSCHLAYP------ASSRASRGRMQRCVRCPVAYHTSDSCLAAGSKVLSPYSIVCSGHFTP-
-NKRDSTWHVNVNWCFLCSRGVIGAPLPDAGLALFEQSSHYLLSEYKRSSELGKLPMIPVVPAAAAKACGK--GGCLLCC
ESCPAAFHPECLGM-EPPEG---TWCCAECRA---------------GKKPQYHDIVWVKLGNYR-WWPAEICQPRNIPQ
NIQNLKHTVGQFPVQFFGSHDYYWTTQGRVFPYMEGDK-GSTDYKT-NCLNKTFKRALLEAAARYQALKAQRETREAQET
ERSERKPPTYKHIKSNKPVGRVQVYTADVSEIPRCNCKPTDESPCGLDSECLNRMLQYECHPSICPAGDRCQNQAFTKRA
YPPSQIVKTA-GRGWGLLTLVSIRK------------------GEFVNEYVGELIDEEECRKRIKYAHEKNLSNFYMLTI
EKDRIIDAGPKGNFSRFMNHSCQPNCETQKWTVNGDTRVGLFATSDIATG-TELTFNYNLDCLGNE-KTICKCGAPNCSG
FLGVRPKTA-----AAAATEEKAKKAKRKARGRRPRTETARAEHEDECYRCGDGGELVMCDKKACPKAYHLSCLNLTKPP
FG-----------KWECPWHHCDV--CGRPSVRSCELCPNSFCKEHQAGLLTRLTRDGRICCEEHD--------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Latimeria_chalumnae_NSD1
-----------------------------------------------------------MDQAHELCRINCLLPFSNPVE
LEAPDNKQFNGRDPGNPFEPGNGCTMELPAAFQNTASKSAQDHSACYSPLRRLQDLASMIN--MDYLDINGSKDGAKPVQ
APGKIHLRPEVPQAYTTLKTDYRSSPTES---------------------------------------------------
------------------------------------------------ESIHNSSPELKLKITKVQSRCFEPVFGEGAQG
DIQITSLDQASEREKEGKQRTKRKKKVAKNDISCHLDSKEENVTEKRRRRRKTTSKLERSGGSKTEFAPLTPMLHAEIKQ
NCRELQEN----TVGKIETIELCRVPLKLENSSCKIEELYHEAKFSYTAETKDNTEKTENKIKPRGADTIHSSVNLDFCS
IKKKPVPVKYKVGDLVWAKLNRRPWWPCRVCSDPLLDTHSKMK--VPSRRPC-----RQYYVQNVGDLSDQAWVAGKATV
LFEGRHQFEEL---PVCRR-GKQKEKPYTYKISQKLLPVWEMSVKIAEDAFSKSAKDQGYSSESKDSSKAKDDISTEMES
HA----------KCLINGCVKSSDSFCGKSGSEKIKIPSETTAKKNSSGNKRRARVRKITNT------------------
------CEKFVTESADRIKENHIKHPTSGEREDSVGGLEDDHTSNFGSKHNAAEDKVSIVLSNTGNKTTEKKVSMSTGAI
NDLVCSPCLHYKQTPS----------------------------------------------------------------
--TTLLDVSCEI--------------------------------------------------------------------
------------NKTKVEKKKDSGAFCNTEEHQKSGRKLKGLSTLSNNVKKTPRSLKKN---------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------VKKERKKCTKSNETVEGYNSGPEEEETLSLKSDIAVLEDKCSETGPTGLETLTTALSRKNSEV
STKLPEKFLIASPVHHNSNEDSKLSTLSHMIASPFNPFSKNTSRPPRNRSVKFRSEDVGFPLPPKTESATKCPSVEVK-E
LAGPSLVSAAKAKGVHDQKPSSSPHGNSTEIENAVVKHVLSELKELSFRSLNKEDGNSVTSKTMAPKDPTGVCVANNLHA
NQNYKFSTLLMLLKDFHDKSKEVKKTAHQNMVGFNVPHTVNCSETNSSEELKPSVSNGSVDGSDEAEGVIQEVSPNRNPE
K------LPVVRITATKLSEIKNESIPSNVRNATKNVTSTLAKSKRVVKKDNLSKEIDSSTNEDSKFEFHVDSSVNHVHN
GVDDSALEKCRHFNGSVKKLVDFRSTETDQVINKDHTPREEESLQKTDK-----------------------KPKMDKGI
LEKAITDEEDGAQQEAKFNNKHSPSCTSTDLNSVAPKKRWKQFSQNTVKTNKRLIKSRERHRSLVPSEEIKDCSRNLKCK
PELETVSQQAEDKLCENLKQNKSLSTATLEILDCVKSSKFAQFSLQR-SIPQLTLAKDLKFLQSEKKRLRKPSKRLLEYT
EEYDQIFAPKKKQKKSVDHSLKVRCMEQASLLRALLPEQQTSSPGAPAPVERA----------SSPGAPAPAERASSPGA
SAPAERASSP----GAPAPAEQASLPGALPLAEQASSPRASPLLEQASLPG-----ALPPVYERKRLRKPTKKLLES-TD
LDPGFVPNKFSCALSLSFFSNNSLENGSFQYCAFSKHSGHEKGSKVLFW---------------------------LLRK
RLRQKASSSVTPNKKVKSEPREEIPDAEGQTSSSDHGDHLKEQAEDMCDPDRAVSSLKKPQTERGGGAAMKENVCQVCEK
PGE--LLLCEAQCCGAFHLQCIGLTRMPEGKFICSECSTGIHTCFICKINGA------DVKRCLVPICGKFYHEECVKKF
PPTAMQNRG-FRCSLHTCLSCHAVN------PSNSSASKGRLLRCVRCPVAYHATDFCMAAGSMILASNSIICPNHFTP-
RKGCKNHEHVNVSWCFVCSE-----------------------------------------------------GGSLLCC
ESCPAAFHRECLNI-DMPEG---NWYCNDCKA---------------GKKPHYKEVVWVKVGGYR-WWPAEVCHPKNIPP
NIQKMKHDIGEFPVHFFGSKDYLWTHQARVFPYMEGDVSSKDKMG--KATDGTYKKALQEAAVRFEELKAVKEMRQLQED
KKNDKKPPPYKPIKVNRPVGKVQIFTADLSEIPRCNCKASDENPCGLDSECINRMLMYECHPNVCPAGEGCQNQCFTKRN
YPHVEIFRTM-GRGWGLCSKVDLKK------------------GEFVNEYVGELIDEEECRARIKHAQENDISNFYMLTL
DKDRIIDAGPKGNHARFMNHSCQPNCETQKWTVNGDTRVGLFALCDIPAG-SELTFNYNLECLGNG-KTVCKCGSPNCSG
FLGVRPKN------QPSSTDDKSKKLKKKPQLKRKSQAEVTKEREDECFSCGDPGQLVSCKKPGCPKVYHADCLNLKKRP
AG-----------RWECPWHQCDM--CGQEAASFCEMCPSSFCEKHRDEKLFISKLDGRLCCTEHDPCGPNPLEPGEIRE
YTLPPK---------------------------------------------NQPDNQNPPTNESTIKPIKLQS-------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Ciona_intestinalis_NSDa
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------RCIRCPTAFHIGDDCIAAGSILLPGLNIICPDHFEP-
LKTTPHHQPVHVSWCFVCSK-----------------------------------------------------GGQLMCC
ETCPAAFHPLCVGFPQTPEG---EWFCRDCRY---------------KKRPLYGEIVWVKLGSYR-WWPGEITHPNEIPD
NIQRLHHGIGEFVVRFFGSNDYFWLNKRRVFAYQEGDTGATSTNCS-RGISSVFNKALQEAQESFEELMSYRQKLQDVKT
QK---KRPMYKHIKTNKPVGGVQIYTAELSEIARCICKKTDPNPCGPESECLNRMLMYECHSDLCPAGEKCQNQRFQKRE
YPSSEVFKTS-WGGWALRAKDLIKK------------------GEFVSEYVGELVDSEECMRRIEDAHKNNVTNFYMLTI
DKDRIIDAGPKGNYSRFMNHSCDPNCETQKWMVNGDTRVGLFALREIQDG-EELMFNYNLDCLGND-KTPCMCGSANCSG
FIGVRPKP------QMGENGNNG-KSVKRKRRRQESKNVP--KHDDFCFRCRQVGTLVCCDVRACQRAFCLRCLRLTKSP
FG-----------KWQCPWHHCDF--CGRRAQNFCHFCPNSFCSSHVANQLLPSVPNKYDCCTDHD--------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Ciona_savignyi_NSDb
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----ELIHCIGGCCQSFHPGCLEDKVSSVADFTCKHCKDDNHACFICKKNSSVETQLGEVKRCTVLKCGRSYHSECLIAQ
AMINSS-----KCTLHQCGTCTTK-------EKEDTNNVANPSRCIKCPTAFHIGDECIAAGSIMLPGLNIICPDHFEP-
LKTTPHHQPVHVSWCFVCSK-----------------------------------------------------GGELMCC
ETCPASFHPICVGLDKTPDD---EWFCRDCRN---------------KKRPLYGEIVWVKLGSYR-WWPGEITHPNEIPD
NIQRLQHGIGEFVVRFFGSNDYFWLNKRRVFAYQEGDTGATSSNCS-RGISSVFNKALQEAQESFEELVSRQQKIQDVKQ
QK---KRPVYKHIKVNRPIGSVQIYTAELSEIPRCICKKTDPNPCGPESECLNRMLMYECHADLCPAGDKCQNQHFQKRD
YPQSEVFKTT-WGGWALKTKTLIKKVTLPGHAPIFMIINSNPQGEFVSEYVGELVDGEECMRRIEHAHKNNVTNFYMLTI
DKDRIIDAGPKGNYSRFMNHCCDPNCETQKWTVNGDTRVGLFALGEIAAG-EELTFNYNLDCLGND-KTPCMCGSSNCSG
FIGVRPK---------NGNGNN--KSVKRKRRRNESKNLP--KHDDFCFRCRQVGTLVCCDVRACQRAFCLACLRLTKPP
FGECLLFVLSGACKWQCPWHHCDF--CGRRAQHFCHFCPNSFCASH----------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Drosophila_melanogaster_NSD
-----------------------------------------------------MKLSTDAHSEIEGDAAHGNVLCNSASD
SLTATDEVAAGNDESVATEGDDVEIPRDTNNSTPVRLLDKPGQNPVQNGAQPAAEESELESQRQTPVQKQQQQRVSMVNR
KRDLINLQSALSPKYIGYANANSPTPLSDSDDTIRTTRRRVNQAAALNNSSAG---------------------------
-----------------ETLAHDNASPRTPGGGGGGGGDDSANQLLSKTYMSPIEKLLIKNGASSPNSTGFEAGSEDLGI
RPIVRKHVKRKMKRVPKAKVTLELDEKNQQEVDEKSVKTEPIDEEVDRTDEAPTQEAQTTAISIKSETEAEHKAAVDVHI
KQEDTIRLDIVNNPVESTSIVITEEPKDLEKSTEELAFALPLASSTEVDLKSPPDLSSTALATSIKSPSSVSIDSAKGLS
IVTDPGWPTYQVGDLFWGKVFSYCFWPCMVCPDPLGQIVGNMPSHPQRSSLDNANVPIQVHVRFFADNGRRNWIKPENLL
TFAGLKAFDDMREELRIKHGPKSAKYRQMVPKRTK-VVIWRQAIEEAQAMTQIPYSDRL---------------------
---------------------EKFYQTYENVVTLNRQKRKRTKYMMQDTSDVGSSLYDSTDN------------------
--------------LHNKQGTQLLAVKRERSESPFSPAFSPVKSKN----------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------EKRAKRRKLSNG
TEADTGSNSMAVTPSQTETTVDSSAYENPEFRQLLSAVMEYVMMNR-----------------------------SDEKV
EKVLLSVVSNIWSLKQIQLRELER--------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------DLASGEIEEPLG
SSVVGRGSGVGTIKRLSNR-------------------------------------------------------------
-------------------------------------------------------------LMTMMVRRSMTPVVTPSTT
PAPSEPDRRLSEPPKTKKPVNRPIEEVIED---------------------------------------------ILQLD
SKYLFRGLSREPICKYCYQAGSDLVRCSRTCSSWLHADCLERKVTGAPMPKIGSRKALVIPPTSKSPSPDEDHVTADAKE
VVAVGTSLVCHECNVGEPEGCVICHQVESPAVPSTPRKEDSSSHTPIEDKLL---------TCSQPMCGKRFHTSCCKYW
PQASSSKHS-ARCPRHVCHTCVSDDP----SGKFQQLGSSKLAKCVRCPATYHQLSKCIPAGTQMLNTTNIICPRHNIA-
----KADAHVNVLWCYICVK-----------------------------------------------------GGELVCC
ETCPIAVHAHCRNIPIKTNES---YICEECES---------------GRLPLYGEIVWAKFNNFR-WWPAIILPPTEVPS
NILKKAHGENDFVVRFFGTHDHGWISRRRVYLYIEGDTGDGHKTKS--QLFRNYTTGVEEASRFLPIIKARRQEQDMERQ
SGNKLHPPPYVKIKTNKAVPPLRFSQ-NLEDLSTCNCLPVDEHPCGPEAGCLNRMLFNECNPEYCKAGSLCENRMFEQRK
SPRLEVVYMN-ERGFGLVNREPIAV------------------GDFVIEYVGEVINHAEFQRRMEQKQRDRDENYYFLGV
EKDFIIDAGPKGNLARFMNHSCEPNCETQKWTVNCIHRVGIFAIKDIPVN-SELTFNYLWDDLMNNSKKACFCGAKRCSG
EIGGKLKDD-------AVKAHAKLKQMRRAKASAVRIHVKPKKTPKVKHISADDEPMDAKDE------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Capitella_teleta_NSD
--------------------------------------------------------------------------------
----------------------------MEDLSQEFSPERVSAEAAASPPSVPSPASHAPVINASPTPIKLRIRRSVCDG
KTEVSSEEIIEGPP------------------------------------------------------------------
-------------------------------------------------APSPQIPVAAAAPPPKRARTKG---------
-----------------------ELKKQLQEKRGKRGGLLPVLPPPPEPLPPPLQPPLPPITQKP---------------
----------------------------------------KLELKQPD--------------------------------
--PDAKDAKFLIGDMLWGRVAGHPWWPCMVGYDPFQGIFTRIQ-----RAKA-----RMTHVHFFGSEGERGWVPDKSLI
PFEGKEAFEKYCS----MMQDKDKKNKKNYIIAGRRRKAWEFAVKDAESAQPLSKAERQ---------------------
--------------------------ALFAVAPPVEDSLKRPSDTTPPVAKRQKRSQSITSP------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------MENQSVAQFTVFCMRRRDALKRDHPDFSPEQVDELLKT----------------------------------
----QWDSLDADQKSLFIPMG-----------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------QDFAHLS
KHMPQTTAPTGKSDGPPS--------------------------------------------------------------
----------------------------------------------------------------VEELKPRNLDSLLDKV
VEQHVSEEVCFSGDAFHLQHFNLQGD------------------------------------------------STKDEI
APKKKSRTCKVKEESSDSTDAQDSDVAGEKAR-------RLAMPSIEWTDGCPPYDLELLKLTTTSASVRKESLCGVCEK
PNE--LLHCVGPCLGHFHAACLGLSVVPTSTFKCDECSTGIHSCFTCKKADK------ETKKCSSHGCGKFYHMKCVSGI
RSAKVDNGH-FTCPLHACATCAVDD------VYKPKPKQNRLLRCVRCPTAYHAGDFCVSAGSQQLNGQSIICGDHFQP-
VKGNSHHTMYHMSWCFACSV-----------------------------------------------------GGTLLCC
DTCPCAYHAECLNI-QPPEG---AWHCELCTN---------------GKRPVFGDIIWVKLGMYRRWWPSEICHPKNVPT
NIQNMRHQLGEFPVKFLGTHDYFWLHRGRVFEYEEDDKATTLKASESNSLGKSFNQAVKEAALVNKMWNTIKEQLKGDID
QK---KPSAYKHIKSNFPIGSVQIYKSPSN---VCECTAQMENPCGEQGNCLNRLTLVECHPQMCKAGEKCQNQRFMKRE
YPDQSAYRTG-ARGWGLKTNVDIKK------------------GQFVNEYVGDLIDSEECQRRIKAAHDNNIVNFYMLTL
DNRRIIDAGPKGNLSRFMNHSCDPNLVTQKWTVNGDVRVGLFAVCDIPAG-TELTFNYNLAAVGST-KTVCQCKSANCSG
FLGIPPKQ------NSSSDSEKPKKKKKKKEKKKK-------IYDNDCYRCGDGGELLLCDQTTCPRAYHLKCLNLEKPP
TG-----------QWCCPWHHCDD--CGRRALKLCSECPNSFCPQHLEGNIF----------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Helobdella_robusta_NSD
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------MTT------TALKCNVNNCSFYYHVNCLKTL
KYGKCEKRS-LTCSHHTCASCAADAE------KMGMAERGKMLKCIVCPNAYHTGDLCIAAGSRILSNGWIICGDHHQMS
DNKRKHQEHVNVAWCFSCGE-----------------------------------------------------GGSLVCC
ENCPASFHPACCET-PPSEEE--KWICELCLD---------------GKRPLYGEIVWCKAGIYR-WWPGEICHPRNVPT
NIQNIAHGIGDFPVRFFGSYDYLWTHKGRVFSFQEGDKKGAKRGSS-KSFVEVFSKALDEADVAARIYYDERNKK---DL
KVYDKKPGPYKHVKSNVPIGKVEIFKVPLTEIPRCQCSPEMPSPCGPDSDCINRLMMYECDVAVCPAGEMCLNRAIQSRW
DVDTEYFRTADNRGWGLRTKIDIKK------------------GQFIHEYVGDLIDEEECKERLRRAKESNVTNFYMLTL
DKNRIIDAGPKGNNSRFMNHSCQPNCETQKWNVNGDVRVGLFAMRFIEAG-EELTFNYNFDCLGDK-KTICHCGMPVCSG
FLGERPKS-------TSTEAERTLITKKKKRRARNVTK-DLIVHEDLCFRCGLGGELVLCDKTGCTKSYHLDCLNLNHLP
RG-----------KWICPWHLCNEENCGKWSSQLCSMCPNSFCSRHTEGNIIVLAT-GRIVCDDHPPSCPQL--------
-QYLLSKDWEELKSRD----------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Trichoplax_adhaerens_NSD
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------MISPK
KVKGRGNKATSNKVEKRKLSKPRSRARESPGS---------------------------------------KGVCMLCEG
IGE-KLVTCQGGCFSKFHLECLGITEWPVKGFKCQECTSGTRKCFVCGSSEP------PVLPCKVAGCGKCYHDTCISQF
TCGQVSEEGCIRCPRHVCTTCTAFAISKN-DENFDVVIQKKLARCIYCPVSYHASEACLPAGCKVLNSSAIICNKHLDA-
-----KVKHVNVGWCFACSQ-----------------------------------------------------GGNLICC
ELCPASYHENCLDEKCRPKPNEDKWFCRGCID---------------GKFPVIGDIVWVKIGAYR-WWPAEVCNRKYVPD
NILALKHGPGEFSVQFLGSHDYSWTSISRIFGYEEEDIDGRASKLGRKGIVKSFGKALKEAEEKFTQRKISREKKEAKSQ
ERRSQKPPSYKHIKMNKLVD--ALIRPNLTEYTPCSCKPTDEAPCGSSSNCINRMLMCECNSSMCPAGDKCQNQRFQKLE
YAKSEIFKSN-QCGWGLKSAEDIYA------------------GTLVVEYVGELLNEKTCYQRIKMAQSKGEKNFYMLNI
DKDVIIDAGQKGNLARFMNHSCQPNCETHKWTVNGLTCIGLFAIDDIKQG-EELTFDYRLHAVGND-QAECHCGSKLCRK
YLGAKIKSTTTTKGKDGGNNKSNKNNNGQGKRKKRKKRKRAIKHEDECYVCGDGGQLIMCSRKSCYKCYHLECLTIDGIP
RG-----------KWDCPWHHCDI--CGKAANQLCSRCPNSFCKTHANGRIQSKNSCGEMVLLCHQCIDDDQDINKSN--
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Pan_troglodytes_NSD1
------------------------------------------------------------------MDQTCELPRRNCLL
PFSNPVNLDAPEDKDSPFGNGQSNFSEPLNGCTMQLSTVS-GTSQNAYGQDSPSCYIPLRRLQDLASMINVEYLNGSADG
SESFQDPEKSDSRAQTPIVCTSLSPGGPT---------------------------------------------------
------------------------------------------------ALAMKQEPSCNNSPELQVKVTKTIKNGFLHFE
NFTCVDDADVDSEMDPEQPVTEDESIEEIFEETQTNATCNYETKSENGVKVAMGSEQDSTPESRHGAVKSPFLPLAPQTE
TQKNKQRNEVDGSNEKAALLPAPFSLGDTNITIEEQLNSINLSFQDDPDSSTSTLGNMLELPG---TSSSSTSQELPFCQ
PKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMK--VSNRRPY-----RQYYVEAFGDPSERAWVAGKAIV
MFEGRHQFEEL---PVLRRRGKQKEKGYRHKVPQKILSKWEASVGLAEQYDVPKGSKNRKCIPGSIKLDSEEDMPFEDCT
ND-PESEHDLLLNGCLKSLAFDSEHSADEKEKPCAKSRARKSSDNPKRTSVKKGHIQFEAHK------------------
------DERRGKIPENLGLNFISGDISDTQASNELSRIANSLTGSNTAPGSFLFSSCGKN-----TAKKEFETSNGDSLL
GLPEGALISKCSREKNKPQ-------------------------------------------------------------
---RSLVCGSK-VKLCYIG-------------------------------------------------------------
--------------AGDEEKRSDSISICTTSDDGSSD--LDPIEHSSESDNSVLEIPDAFDRTENMLSM-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------QKNEKIKYSRFAATNTRVKAKQKPLISNSHTDHLMGCTKSAEPG-TETSQVNLSDLKASTLVHKPQSD
FTNDALSPKFNMSSSISSENSLIKGGAANQALLHSKS-KQPKFRSIKCKHKENPVMVEPPVINEECSLKCCSSDTK---G
SPLASISKSGKVDGLKLLNNMHEKTRDSSDIETAVVKHVLSELKELSYRSLGEDVSDSGTSKPSKPLLFSSASSQNHIPI
EPDYKFSTLLMMLKDMHDSKTKEQRLMTAQNLVSYRSPGRGDCSTNSPVGVSKVLVSGGSTHNSEKKGDGTQNSANPSPS
G-GDSALSGELSASLPGLVSDKRD---LPASGKSRSDCVTRRNCGRSKPSSKLRDAFSAQMVKNTVNRKALKTERKRKLN
QLPSVTLDAVLQGDREHG----GSLRGGAEDPSKEDPLQIMGHLTSEDG-DHFSDVHFDSKVKQSDPGKISEKGLSFEN-
--GKGPELDSVMNSEN---DELNGVNQVVPKKRWQRLNQRRTKPRKRMNRFKEKENSECAFRVLLPSDPVQEGRDEFPEH
RTPPSASILEEPLTEQNHADCLDSVGPRLNVCDKSSASIGDMEKEPGIPSLTPQAELPEPAVRSEKKRLRKPSKWLLEYT
EEYDQIFAPKKKQKKVQEQVHKVSSRCEEESLLARGRSS--AQNKQVDENSL-----------ISTKEEPPVLEREAPFL
EGPLAQSELG------GGHAELPQLTLSVPV-APEVSPRPA-------LESEELLVKTPGNYESKRQRKPTKKLLES-ND
LDPGFMPKKGDLGLSKKCYEAGHLENGITESCATSYSKDFGG--GTTKIFDK-----------------------PRKRK
RQRHAAAKMQCKKVKNDDSSKEIPG-SEGELMPHRTATSPKETVEEGVEHDPGMPASKKMQGERGGGAALKENVCQNCEK
LGE--LLLCEAQCCGAFHLECLGLTEMPRGKFICNECRTGIHTCFVCKQSGE------DVKRCLLPLCGKFYHEECVQKY
PPTVMQNKG-FRCSLHICITCHAAN------PANVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTP-
RRGCRNHEHVNVSWCFVCSE-----------------------------------------------------GGSLLCC
DSCPAAFHRECLNI-DIPEG---NWYCNDCKA---------------GKKPHYREIVWVKVGRYR-WWPAEICHPRAVPS
NIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMG--KGVDGTYKKALQEAAARFEELKAQKELRQLQED
RKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFSKRQ
YPEVEIFRTL-QRGWGLRTKTDIKK------------------GEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTL
DKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAG-TELTFNYNLECLGNG-KTVCKCGAPNCSG
FLGVRPKN------QPIATEEKSKKFKKKQQGKRRTQGEITKEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRP
AG-----------KWECPWHQCDI--CGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIRE
YVPPPVPLPPGPSTHLAEQ-STGMAAQAPKMSDKPPADTNQTLSLSKKALAGTCQRPLLP-ERPLERTDSRPQPLDK---
--VRDLAGSGTKSQSLVSSQRPLDRPPAVAGPRPQLSDKPS-PVTSPSSSPSVRS--------QPLERPLGTADPR---L
DKSIGAASPRPQSLEKTPV-------------PTGLRLPPPDRL------------------------------------
------------------------------------------------------LITSSPKPQTSDRPTD----------
------------------------------------------------------------------------KPHASLSQ
RLPPPEKVLS-------AVVQTLVAKEKALRPVDQNTQS----KNRAALVMDLIDLTPRQKERAASPHEVTPQADEKMPV
LESSSWPASKGLG----HMPRAVEK-GCVSDP-LQTSGKAAAPS-EDPWQAVKSLTQARLLSQPPAK-AFLYEPTTQASG
RASAGAEQTPGPLSQSLGLVKQAKQ----MVGGQQLPALAAKSG----QSFRSLGKAPASLPTEEK-----KLVTTEQSP
WALG--KASSRAGLWPIVAGQTLAQSCWSAGSTQTLAQTCWSLGR-----GQD--PKPEQNTLPALNQAPSSHKCAESEQ
K
>Gorilla_gorilla_NSD1
------------------------------------------------------------------MDQTCELPRRNCLL
PFSNPVNLDAPEDKDSPFGNGQSNFSEPLNGCTMQLSTVS-GTSQNAYGQDSPSCYIPLRRLQDLASMINVEYLNGSADG
SESFQDPEKSDSRAQTPIVCTSLSPGGPT---------------------------------------------------
------------------------------------------------ALAMKQEPSCNNSPELQVKVTKTIKNGFLHFE
NFTCVDDADVDSEMDPEQPVTEDESIEEIFEETQTNATCNYETKSENGVKVAMGSEQDSTPESRHGAVKSPFLPLAPQTE
TQKNKQRNEVDGSNEKAALLPAPFSLGDTNITIEEQLNSINLSFQDDPDSSTSTLGNMLELPG---TSSSSTSQELPFCQ
PKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMK--VSNRRPY-----RQYYVEAFGDPSERAWVAGKAIV
MFEGRHQFEEL---PVLRRRGKQKEKGYRHKVPQKILSKWEASVGLAEQYDVPKGSKNRKCIPGSIKLDSEEDMPFEDCT
ND-PESEHDLLLNGCLKSLAFDSEHSADEKEKPCAKSRARKSSDNPKRTSVKKGHIQFEAHK------------------
------DERRGKIPENLGLNFISGDISDTQASNELSRIANSLTGSNTAPGSFLFSSCGKN-----TAKKEFETSNGDSLL
GLPEGALISKCSREKNKPQ-------------------------------------------------------------
---RSLVCGSK-VKLCYIG-------------------------------------------------------------
--------------AGDEEKRSDSISICTTSDDGSSD--LDPIEHSSESDNSVLEIPDAFDRTENMLSM-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------QKNEKIKYSRFAATNTRVKAKQKPLISNSHTDHLMGCTKSAEPG-TETSQVNLSDLKASTLVHKPQSD
FTNDALSPKFNMSSSISSENSLIKGGAANQALLHSKS-KQPKFRSIKCKHKENPVMVEPPVINEECSLKCCSSDTK---G
SPLASISKSGKVDGLKLLNNMHEKTRDSSDIETAVVKHVLSELKELSYRSLGEDVSDSGTSKPSKPLLFSSASSQNHIPI
EPDYKFSTLLMMLKDMHDSKTKEQRLMTAQNLVSYRSPGRGDCSTNSPVGVSKVLVSGGSTHNSEKKGDGTQNSANPSPS
G-GDSALSGELSASLPGLVSDKRD---LPASGKSRSDCVTRRNCGRSKPSSKLRDAFSAQMVKNTVNRKALKTERKRKLN
QLASVTLDAVLQGDREHG----GSLRGGAEVPSKEDPLQIMGHLTSEDG-DHFSDVHFDNKVKQSDPGKISEKGLSFEN-
--RKGPELDSVMNSEN---DELNGVNQVVPKKRWQRLNQRRTKPRKRMNRFKEKENSECAFRVLLPSDPVQEGRDEFPEH
RTPPSASILEEPLTEQNHADCLDSVGPRLNVCDKSSASIGDMEKEPGIPSLTPQAELPEPAVRSEKKRLRKPSKWLLEYT
EEYDQIFAPKKKQKKVQEQVHKVSSRCEEESLLARGRSS--AQNKQVDENSL-----------ISTKEEPPVLEREAPFL
EGPLAQSELG------GGHAELPQLTLSVPV-APEVSPRPA-------LESEELLVKTPGNYESKRQRKPTKKLLES-ND
LDPGFMPKKGDLGLSKKCYEAGHLENGITESCATSYSKDFGG--GTTKIFDK-----------------------PRKRK
RQRHAAAKMQCKKVKNDDSSKEIPG-SEGELMPHRTATSPKETVEEGVEHDPGMPASKKIQGERGGGAALKENVCQNCEK
LGE--LLLCEAQCCGAFHLECLGLTEMPRGKFICNECRTGIHTCFVCKQSGE------DVKRCLLPLCGKFYHEECVQKY
PPTVMQNKG-FRCSLHICITCHAAN------PANVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTP-
RRGCRNHEHVNVSWCFVCSE-----------------------------------------------------GGSLLCC
DSCPAAFHRECLNI-DIPEG---NWYCNDCKA---------------GKKPHYREIVWVKVGRYR-WWPAEICHPRAVPS
NIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMG--KGVDGTYKKALQEAAARFEELKAQKELRQLQED
RKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFSKRQ
YPEVEIFRTL-QRGWGLRTKTDIKK------------------GEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTL
DKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAG-TELTFNYNLECLGNG-KTVCKCGAPNCSG
FLGVRPKN------QPIATEEKAKKFKKKQQGKRRTQGEITKEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRP
AG-----------KWECPWHQCDI--CGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIRE
YVPPPVPLPPGPSTHLAEQ-STGMAAQAPKMSDKPPADTNQTLSLSKKALAGTCQRPLLP-ERPLERTDSRPQPLDK---
--VRDLAGSGTKSQSLVSSQRPLDRPPAVAGPRPQLSDKPS-PVTSPSSSPSVRS--------QPLERPLGTADPR---L
DKSIGAASPRPQSLEKTPV-------------PTGLRLPPPDRL------------------------------------
------------------------------------------------------LITSSPKPQTSDRPTD----------
------------------------------------------------------------------------KPHASLSQ
RLPPPEKVLS-------AVVQTLVAKEKALRPVDQNTQS----KNRAALVMDLIDLTPRQKERAASPHEVTPQADEKMPV
LESSSWPASKGLG----HMPRAVEK-GCVSDP-LQTSGKAAAPS-EDPWQAVKSLTQARLLSQPPAK-AFLYEPTTQASG
RASAGAEQTPGPLSQSSGLVKQAKQ----MVGGQQLPALAAKSG----QSFRSLGKAPASLPTEEK-----KLVTTEQSP
WALG--KASSRAGLWPIVAGQTLAQSCWSAGSTQTLAQTCWSLGR-----GQD--PKPEQNTLPALNQAPSSHKCAESEQ
K
>Macaca_mulatta_NSD1
------------------------------------------------------------------MDQTCELPRRNCLL
PFSNPVNLDAPEDKDSPFGNGQSNFSEPLNGCTMQLSTVS-GTSQNAYGQDSPSCYIPLRRLQDLASMINVEYLNGSADG
SESFQDPEKSDSRAQTPIVCTSLSPGGPT---------------------------------------------------
------------------------------------------------ALAMKQELSCNNSPELQVKVTKTIKNGFLHFE
NFTCVDDADVDSEMDPEQPVTEDESIEEIFEETQTNATCNYETKSENGVKVAMGSEQDSTPESRHGAVKSPFLPLAPQTE
TQKNKQRNEVDGSNEKAALLPAPFSLGDTNITIEEQLNSINLSFQDDPDSSTSTLGNMLELPG---TSSSSTSQELPFCQ
AKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMK--VSNRRPY-----RQYYVEAFGDPSERAWVAGKAIV
MFEGRHQFEEL---PVLRRRGKQKEKGYRHKVPQKILSKWEASVGLAEQYDVPKGSKNRKCIPGSIKLDSEEDMPFEDCT
ND-PESEHDLLLNGCLKSLAFDSEHSADEKEKPCAKSRARKSSDNPKRTSVKKGHIQFEAHK------------------
------DERRGKIPENLGLNFISGDISDTQASNELSRIANSLTGSNTAPGSFLFSSCGKN-----TAKKEFETSNGDALL
GLPEGALISKCSREKNKPQ-------------------------------------------------------------
---RSLVCGSK-VKLCYIG-------------------------------------------------------------
--------------AGDEEKRSDSISICTTSDDGSSD--LDPIEHSSESDNSVLEITDAFDRTENMLSM-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------QKNEKIKYSRFAATNTRVKAKQKPLISNSHTDHLMGCTKSAEPG-TETSQVNLSDLKASTLVHKPQSD
FTSDDLSPKFNMSSSISSENSLIKGGAVNQALLHSKS-KQPKFRSIKCKHKENPVMVEPPVTNDEYSLKCCSSDTK---G
SPLASISKSGKVDGLKLLNNMHEKTRDSSDIETAVVKHVLSELKELSYRSLGEDVSDSGTSKPSKPLLFSSPS-QNHIPI
EPDYKFSTLLMMLKDMHDSKTKEQRLMTAQNLVSYRSPGRGDCSTNSPVGVSKVLVSGGSTHNSEKKGDGTQNSANLSPS
G-GDSALSGELSASLPGLVSDKRD---LPVSGKSRSNCVTRRNCGRSKPSSKLRDAFSAQVVKNTVNRKALKTERKRKLN
QLSSVTLDAVLQGDREHG----GSLRGGAEDPSKEEPLQIMGHLTSEDG-DHFSDVHFDNKVKQSDPGKISEKGPSFEN-
--GKGPELDSVMNSEN---DELNGVNQVVPKKRWQRLNQRRTKPRKRMNRFKEKENSECAFGALLPSDPVQEGRDEFPEH
RTS-SASILEEPLTDQKHADCLDSVGPRLNVCDKSSASIGDMEKEPGIPSLTPQAELPEPAVRSEKKRLRKPSKWLLEYT
EEYDQIFAPKKKQKKVQEQVHKVSSRCEEESLLARGRSS--AQNKQVDENSL-----------ISTKEEPPVLEREAPFL
EGPLAQSELG------GGHAELPQLTLSVPV-APEVSPRPA-------LESEELLVKTPGNYESKRQRKPTKKLLES-ND
LDPGFMPKKGDLGLSKKCYEAGHLENGITESCATSYSKDFGG--GTSKIFDR-----------------------PRKRK
RQRHAAAKMQCKKVKNDDSSKEIPS-LEGELMPHRTAASPKETVEEGVEHDSGMPASKKMQGERGGGAALKENVCQNCEK
LGE--LLLCEAQCCGAFHLECLGLTEMPRGKFICNECRTGIHTCFVCKQSGE------DVKRCLLPLCGKFYHEECVQKY
PPTVMQNKG-FRCSLHICITCHAAN------PANVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTP-
RRGCRNHEHVNVSWCFVCSE-----------------------------------------------------GGSLLCC
DSCPAAFHRECLNI-DIPEG---NWYCNDCKA---------------GKKPHYREIVWVKVGRYR-WWPAEICHPRAVPS
NIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMG--KGVDGTYKKALQEAAARFEELKAQKELRQLQED
RKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFSKRQ
YPEVEIFRTL-QRGWGLRTKTDIKK------------------GEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTL
DKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAG-TELTFNYNLECLGNG-KTVCKCGAPNCSG
FLGVRPKN------QPIATEEKSKKFKKKQQGKRRTQGEITKEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRP
AG-----------KWECPWHQCDI--CGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIRE
YVPPPVPLPPGPSTHLAEQ-STGMAAQAPKMSDKPPADTNQTLSLSKKALAGTCQRPLLP-ERPLERTDSRSQPLDK---
--VRDLAGSGTKSQSLVSSQRPLDRQPAVAGPRPQLSDKPS-PVTSPSSSPSVRS--------QPLERPLGTADPR---L
DKSIGAASPRPQSLEKTPV-------------PTGLRLPPPDRL------------------------------------
------------------------------------------------------LITSSPKPQTSDRPPD----------
------------------------------------------------------------------------KPHASLSQ
RLPPPEKVLS-------AVVQTLVAKEKALRPVDQNTQS----KNRAALVMDLIDLTPRQKERAASPHEVTPQADEKMPV
LESSSWPASKGLG----HMPRAVEK-GSVSDP-LQTSGKVAAHS-EDPWQAVKSFTQARLLSQPPAK-AFLYEPTTQASG
RAPAGTEQTPGPLSQVPGLVKQAKQ----MIGGQQLPALAARSG----QSFRSLGKAPASLPTEEK-----KLVTTEQSP
WALG--KASSRAGLWPIVAGQTLAQSCWSPGSTQTLTQTCWSLGR-----GQD--PKPEQNTLPALNQAPSSHKCAESEQ
K
>Nematostella_vectensis_NSD
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------MFCGDCNSAYHPDCIGLSTAPKGKFKCDECTSGVHSCFVCRQTG-------DVKACSQPLCSKFYHKECLQSY
KCSKIDGDR-IYCPLHFCSTCISN---------KTPVNRGRLTKCIRCPTAYHAG--CLVAGCMPITSHLMVCAKHFLP-
NKSKAHHTHVNVNWCFVCSI-----------------------------------------------------GGTLICC
ESCPAAFHPECISYEGIPEG---RFYCKDCVE---------------GKSLLYGDIVWVKLGMYR-WWPAMICNPRDVPT
NIQSMRHQPGEFPVMFLGSHDFYWIHKGRVFSYQDGDKGT-ESGNN-KYLAKVFKKALVEAKEKYDEWKKAREDKAEQDL
QRFCKKPPQYKHIKTN-KCTTAQRIILDPSEMPVCECTP--DQACGQDANCLNLMLQFECVASRCPAGDKCQNQRFQKRQ
YVDCEPFRAH-SRGWGLRSKQAIKK------------------GTFVIEYVGELIDDATCRERVKKGDDD--TNYYMLTI
DKDCIIDAGPMGNLSRFMNHSCYPNCETQKWTVNGEVRVGLFTSRDVESQ-EELTFDYCLDCHGNE-KKKCHCGSQNCSG
FLGVRPKTQ-----NAQMNEDKAKNAALKRRKRKPKKPAVKQVHEDDCFICGDGGQLIMCDRSGCLKCYHVDCLNLDKKP
QG-----------RWQCPWHFCDN--CGKRATVLCSECPNSFCRSHAQGQINSTDKNTFLCTDHVDEVLPGMTDKFLATD
QVLNALDLINGDLTGIRPTELDHLQQKPEYLELGS---------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Otolemur_garnettii_NSD1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------VSNRRPY-----RQYYVEAFGDPSERAWVAGKAIV
MFEGRHQFEEL---PVLRRRGKQKEKGYRHKVPQKILSKWEASVGLAEQYDVPRGSKSRKCVTSSIKLDSEEDVLFEDCT
ND-PESEHDLLLNGCLKSLAFDSEHSADEKEKPCAKSRARKSSDNPKRTSVKKGFMQFEAHK------------------
------EDRRGKISENLGLNFISGDVSEKQASNELSRIANSLTGSSAVPGNFLFSSCGKN-----TAKKEFETANCDSLL
GLPEGALISKRSGEKKKPQ-------------------------------------------------------------
---RGLLCSSK-VQLCYIG-------------------------------------------------------------
--------------AGDEEKRSDSISICTTSDDGSSD--LDPVEHSSESDNSVLEITDAFDRTENILSM-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------QKNEKIKYSRYPGTNSRVKAKQKPLITNSHTDNLTDCTKTAEPR-TETSRVNLSDLTVSTPVHKPQSD
FRNDGLSPKFSMASSISSENSLIKGGATNRPLLHSKS-KQPKFRNIKYKHKETSVIVEPPVTNEDCSLKCCSSDMK---G
SHLASISKSGKVDGLKLLNNMHEKTRDSNDIETAVVKHVLSELKELSYRSLGEEVNESGTSKPPKPLLFSSASSQNHIPI
EPDYKFSTLLMMLKDMHDSKTKEQRLMTASNLVSYRSSGRGDCSTSGPAGASKVLVSGGSTHNSEKNRDGIQDSTNPIPS
G-GDSAVSGELSASLPGFVSNRRD---IPASGKSRPNCVTRRTCGRSKPSSKLRDAFSAQMGKNTVNRKALKTERKRKLN
RLPAMTLEAALQGDRESG----GSLTGGTEDLGKDESLQLTGHLTGKDGTEHLSDGHLDNKVKKPEPDKIPEKGPGFENK
KGQKGQELDSEMNSEN---DEPNGVNQAVPKKRWQRLNQRRTKPRKRTNRFREKENSEGAFGVLLPSDPVQEKRDEFLEH
RTPPSTNIPEDALTDTNRAGHLDSVGSQLNIRDKSSTSLGDVEKEPGIPSLTPQAELPEPAVRSEKKRLRKPSKWLLEYT
EEYDQIFAPKKKQKKVQEQVHKVSSRCEEESLVARCRSS--AQNKQVDENNL-----------ISTKEEPPVLEREAPFL
EGPLAQSELG------GGHAELPQLTLSVPV-APEVSPRPA-------LESEELLVKTPGNYESKRQRKPTKKLLES-ND
LDPGFMPKKGDLGLSKKCYEAGRLENGIAD---ASRSKEFGG--GTTKVFDK-----------------------PRKRK
RQRHATTKVQCKKVKSDDSSKETPS-SEGELMTHRTTGSPKETVEEGIEHDSGMPASKKMQGERGGGAALKENVCQNCEK
LGE--LLLCEAQCCGAFHLECLGLTEMPRGKFICNECRTGIHTCFVCKQSGE------DVKRCLLPLCGKFYHEECVQKY
PPTVIQNKG-FRCSLHICITCHAAN------PASVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTP-
RRGCRNHEHVNVSWCFVCSE-----------------------------------------------------GGSLLCC
DSCPAAFHRECLNI-DIPEG---NWYCNDCKA---------------GKKPHYREIVWVKVGRYR-WWPAEICHPRAIPS
NIDKMKHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMG--KGVDGTYKKALQEAAARFEELKAQKELRQLQED
RKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFSKRQ
YPEVEIFRTL-QRGWGLRTKTDIKK------------------GEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTL
DKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAG-TELTFNYNLECLGNG-KTVCKCGAPNCSG
FLGVRPKN------QPIATEEKSKKFKKKQQGKRRSQGEITKEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRP
AG-----------KWECPWHQCDI--CGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIRE
YVPP-VQLPTGPSTHPAEQ-SSGATAQEPKMSDKPPADTNQMLSLSKKALTGTCQRPLLP-ERLLERPDSRTQPLDR---
--VRDLAGSGTKPQSLIPSQRSLDRPP--AGPRPQLSDKPS-PVTGPSSSPSVRS--------QPLERPLGMADPR---L
DKSIGAASPRPQALEKTPV-------------PTGLRLAPPDRL------------------------------------
------------------------------------------------------LISSSPKPQTSDRPSD----------
------------------------------------------------------------------------KSHASLSQ
RLPPPEKVLS-------AVVQTLVAKEKALRPVDQNTQS----KNRAALVMDLIDLTPRQKERAASPHEAIAQADEKMPV
LESSSWSASRGLG----PMPRAVEK-TSMSDSRLQPPGKASAPS-EHSWQAVKSLTQARLLSQPPAK-AFLYEPASQASG
RVSSGAEQSLGPPVQPLGLGKQAKQ----MVGGQQLSGLAAKSG----QTYRSLGKTSASLPTEEK-----KLATTEQSP
WVLG--KTSPGAGLWPMVAGQTLAQSCWSTGSTQTLAQTCWSLGR-----GQD--PKPEQNTLPALNQAPSSYKCAESEQ
K
>Bos_taurus_NSD1
------------------------------------------------------------------MDQTCELPRRNCLL
PFSNPVNLDAPEDKDSPFGNGQSNFSEPLNGCTMQLSTAS-GTSQNAYGQDSPSCYIPLRKLQDLASMINVEYLNGSADG
SESFQDPEKSDSRAQSPVVCTSLNPGGPT---------------------------------------------------
------------------------------------------------ALAMKQEPSCNNSPELQVKVTKTVKNGFLHFE
NFTCVDDADVDSEMDPEQPVTEDESIEEIFEETQTNATCNYEPKSENGVDVAMGDEQDSTPDSRHGAGKPPFLPLAPQTE
TQRNKQRSDVDGSHEKAALLPAPLSLGDTNVTIEEQLNSINLSFQDDPDSSTSTLGNMLELPG---TSSSSTSQELPFCQ
PKKKATPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMK--VSNRRPY-----RQYYVEAFGDPSERAWVAGKAIV
MFEGRHQFEEL---PVLRRRGKQKEKGYRHKVPQKILSKWEASVGLAEQYDIPKGSKNRKCVTSSIKLDSEEDMPFEDCT
ND-PESEHDLLLNGCLKSLAFDSEHSADEKEKPCAKSRARKSSDNPKRTSVKKGHMQFETHK------------------
------EERRGKIPENLGLNFISGDVSDKQASNELSRIANSLTGPSTAPGSFLFSSCAKN-----TAKKEFETSNCDSLL
GLSEGALISKRSGEKKKFQ-------------------------------------------------------------
---RGLMCSSK-VQLCYIG-------------------------------------------------------------
--------------AGDEEKRSDSISICTTSDDGSSD--LDPVDHSSESDNSVLEITDAFDRSENLLPV-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------QKNEKVKYSRYPATNTKVKAKQKSLITNSHTDHLINCTKTTEPG-TETSQINLSDLKVSTLVRKPQPD
FRNDGFSPKFNTSSSISSENSIIKGGAKNQALLHSKS-KQPKIRSIKCKHKENPVVAEPPVANEDCSLKCCSSDNK---G
SPLASISKSGKVDGLKLLSNMHEKTRDSSDIETAVVKHVLSELKELSYRSLSEDVSDSGTSKPSKPLLFSSASGQNHIPI
EPDYKFSTLLMMLKDMHDSKTKEQRIMTAQNLVSYRSPGLGDCSTSSPVSAPKVLVSGGSNHSSEKSGDGTQDPVHPGPG
G-GDSALSGELSTSLPGLGSDKRD---LPASGKNRSNCVTRRNCGRSKPS-KFRDGFSAQMGKNTVNRKALKTERRRKLN
ELPAVTLEAALQGDRESRGSEKSSSRGEAEDPGKEPTLQLMGHLTSEDG-AHFSSVSFDNKVNQSDPEKIPEKGPSFEI-
--RKVPELDSEMNSEN---DEPSSINEAVPKKRWQRLNQRRTKPRKRTNRFKEKENSEGAFGVLLSADPVKKE-DEFPEQ
RPPASTNKLEDALTDPNHANHLDSAGPRLNVCDKSNASNEEMEKEPGIPSLTPQPELPEPAVRSEKKRLRKPSKWLLEYT
EEYDQIFAPKKKQKKTQEQVHKVSSRCEEESLLARCRSS--AQNKQVDENSL-----------ISTKEEPPVLEREAPFL
EGPLAQSELG------GGHAELPQLTLSVPV-APEVSPRPA-------LESEELLVKPPGNYESKRQRKPTKKLLES-ND
LDPGFMPKKGDLGLTKKCYEAGHLENDINESCAAPRSKEFGG--GTTKLFDK-----------------------PRKRK
RQRHATAKLHCKKVKNDISSKETPN-SEGELMTHRTAASPKETVEEGVENDHGMPASKKLQGERGGGAALKENVCQNCEK
LGE--LLLCEAQCCGAFHLECLGLTEMPRGKFICNECRTGIHTCFVCKQSGE------DVKRCLLPLCGKFYHEECVQKY
PPTVMQNKG-FRCSLHICTTCHAAN------PASVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTP-
RRGCRNHEHVNVSWCFVCSE-----------------------------------------------------GGSLLCC
DSCPAAFHRECLNI-DIPEG---NWYCNDCKA---------------GKKPHYREIVWVKVGRYR-WWPAEICHPRAVPS
NIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMG--KGVDGTYKKALQEAAARFEELKAQKELRQLQED
RKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFTKRQ
YPEVEIFRTL-QRGWGLRTKTDIKK------------------GEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTL
DKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAG-TELTFNYNLECLGNG-KTVCKCGAPNCSG
FLGVRPKN------QPIATEEKSKKFKKKQQGKRRTQGEVTKEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRP
AG-----------KWECPWHQCDI--CGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIRE
YVPPPVPLPPGPSTHLAEQ-SSGVAAQGPKMSDKPSADTNPSLSLSKKALAGTCQRPPLP-ERPPDRTDSRPQPVDR---
--VRDLAGSGTKPQSLVSSQKPLDRPPAVAGPRPQLSDKPS-PVTGPSSSPSVRS--------QPLERPLGTADPR---L
DKSIGAASPRPQSLEKTPV-------------PTGLRLPPPEKL------------------------------------
------------------------------------------------------LVTSGPKPQTSDRPPD----------
------------------------------------------------------------------------KSHVSLSQ
RLPPPDKVLS-------AVVQTLVAKEKALRPVDQNTQS----KNRAALVMDLIDLTPRQKDRAGSPHELTPQADEKMPV
LESSSWPASKGLG----QIPRAVER-GSVSDAVLQPLGKAAATS-EHSWQAVKSLTQARLLSQPPAK-AFLYEPATQASG
RAPAGAEQTPGPPSQAPGLVKQVKQ----MAGGQQLPGLAAKSG----QSFRPLGKS--SLSTEEK-----KLAPTEQSP
WALG--KASPGPGLWPMVAGQTLAQSCWSSGSTQTLAQTCWSLGR-----GKD--PKPEQSTLPALNQAPSSHKCAESEQ
K
>Felis_catus_NSD1
------------------------------------------------------------------MDQTCELPRRNCLL
PFSNPVNLDAPEDKDSPFGNGQSNFSEPLNGCTMQLSTAS-GTSQNAYGQDSPSCYIPLRRLQDLASMINVEYLNGSADG
SESFQDPEKSDSRAQSPVVCTSLSPGGPT---------------------------------------------------
------------------------------------------------ALAMKQEPSCNNSPELQVKVTKTIKNGFLHFE
NFTCVDDADVDSEMDPEQPVTEDESIEEIFEETQTNATCNYEPKSENGVDVAMGNEQDSTSESRNGAVKSPFLPLAPQTE
TQKNKQRNEVDGSNEKAALLPAPFSLGDTNVTIEEQLNSINLSFQDDPDSSTSTLGNMLELPG---TSSSSTSQELPFCQ
PKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMK--VSNRRPY-----RQYYVEAFGDPSERAWVAGKAIV
MFEGRHQFEEL---PVLRRRGKQKEKGYRHKVPQKILSKWEASVGLAEQYDVPKGSKNRRCVTSSIKLDSEEDMPFEDCT
ND-PESEHDLLLNGCLKSLAFDSEHSADEKEKPCAKSRARKSSDNPKRTSMKKGHIQFEAHK------------------
------EERRGKIPENLGLNFISGDVSDKQASNELSRIANSLTGSSTAPGNFLFSSCAKN-----TAKKEFETSNCDSLL
GLSEGALISKHSGEKKKLQ-------------------------------------------------------------
---RGLVCSSK-VQLCYIG-------------------------------------------------------------
--------------AGDEEKRSDSISICTTSDDGSSD--LDPIDHSSESDNSVLEITDAFDRTENILSV-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------QKNEKVKYTRYPATNTKVKAKQKSLITNSHTDHLMDCTKTGEPG-TETSQVNLSDLKVSTLIRKPQSE
FRNDGFSPKFNTPSSISSENSLIKGGATSQALLHSKS-KQPKIRSIKCKHKENPVVVESSVTNEDCSLKCCSSDTK---G
SPLASISKSGKVDGLKLLSNMHEKTRDSNDIETAVVKHVLSELKELSYRSLSEDVSDSGTSKPSKPLLFSPASGQNHIPI
EPDYKFSTLLMMLKDMHDSKTKEQRLMTAQNLVSYRSPGLGDCSTSSPVAASKALVSGSSTHNSEKNGDGTQNPVRPSPS
G-GDSALSGELSVSVPSLVSDRRD---LPASGKSRANCVTRRNCGRSKPSSKLRDSFSSQMGKNTLNRKALKTERKRKLN
RLPAVTLETALQGDRPSGGSENGCSRGGLEDPGKEEPLQLMGHLTSEDS-AHFSSVNFDDKVNQSNPDKIPEKGPSFEN-
--RKGPELDTEVNSEN---DEPNGVNQAVPKKRWQRLNQRRTKPRKRTNRFREKENSEGAFGVLLPADPVKKG-DEFPEH
RPPTSTNILEDALADPNHASCLDSVGPRLNVCDKSSASIEEMEKEPGIPNLTPQPELPEPAMRSEKKRLRKPSKWLLEYT
EEYDQIFAPKKKQKKVQEQVHKVSSRCEEESLLARCRSS--AQNKRVDENSL-----------ISTKEEPPVLEREAPFL
EGPLAQSELG------GGHAELPQLTLSVPV-APEVSPRPA-------LESEELLVKTPGNYESKRQRKPTKKLLES-ND
LDPGFMPKKGDLGLSKKCYEAGHLENDINESRAASHSKEFGG--GTTKIFDK-----------------------PRKRK
RQRHSTAKVHCKKMKNDDSSKETPI-SEGELMTHRTAASPKDTVEEGVENDHGMPASKKLQGERGGGAALKENVCQNCEK
LGE--LLLCEAQCCGAFHLECLGLTEMPRGKFICNECRTGIHTCFVCKQSGE------DVKRCLLPLCGKFYHEECVQKY
PPTVMQNKG-FRCSLHICITCHAAN------PASVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTP-
RRGCRNHEHVNVSWCFVCSE-----------------------------------------------------GGSLLCC
DSCPAAFHRECLNI-DIPEG---NWYCNDCKA---------------GKKPHYREIVWVKVGRYR-WWPAEICHPRAVPS
NIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMG--KGVDGTYKKALQEAAARFEELKAQKELRQLQED
RKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATDDNPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFTKRQ
YPEVEIFRTL-QRGWGLRTKTDIKK------------------GEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTL
DKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAG-TELTFNYNLECLGNG-KTVCKCGAPNCSG
FLGVRPKN------QPIATEEKSKKFKKKQQGKRRTQGEITKEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRP
AG-----------KWECPWHQCDI--CGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIRE
YVPPPVPLPPGPGTHLAEH-SSGVAAQGPKMLDKLPADTNQTLSLSKKALAGTCQRPPLP-ERPPDRTDSRPQPVDR---
--VRDLAGSGTKPQSLVSSQKPLDRPPAVAGPRPQLSDKPS-PVTGISSSPSVRS--------QPLERPLGTADPR---L
DKSIGAASPRPQSLEKAPV-------------PTGLRLPPPDRL------------------------------------
------------------------------------------------------LVTSGPKPQTSDRPPD----------
------------------------------------------------------------------------KSHASLSQ
RLPPPDKVLS-------AVVQTLVAKEKALRPVDQNTQS----KNRAALVMDLMDLTPHQKERAASPHEVTSQIDEKMPV
LESSSWTASKGLG----QMPRAVER-GSVADPILQPPGKAAVPS-EHPWQAVKSLTQARLLSQAPAK-AFLYEPTTPASG
RASVGVEQTPGPPSQAPGLMKQVKQ----MAGGQQLPGLAAKNG----QSFRPLGKAPSSLCTEEK-----KLATAEQSP
WALG--KASPGPGLWPIVAGQTISPSCWSSGSTQTLAQTCWSLGR-----GQD--PKPEQNTLPALNQAPSSHKCAESEQ
K
>Canis_lupus_familiaris_NSD1
------------------------------------------------------------------MDQTCELPRRNCLL
PFSNPVNLDAPEDKDSPFGNGQSNFSEPLNGCTMQLSTAS-GTSQNAYGQDSPSCYIPLRRLQDLASMINVEYLNGSADG
SESFQDPEKSDSRAQSPVVCTSLSPGGPT---------------------------------------------------
------------------------------------------------ALAMKQEPSCNNSPELQVKVTKTIKNGFLHFE
NFTCVDDADVDSEMDPEQPVTEDESIEEIFEETQTNAICNYEPKSENGVDVAMGNEQDSTPESRHGAVKSPFLPLAPQTE
TQKNKQRNEVDGSNEKAALLPAPFALGDTNVTIEEQLNSINLSFQDDPDSSTSTLGNMLELPG---TSSSSTSQELPFCQ
PKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMK--VSNRRPY-----RQYYVEAFGDPSERAWVAGKAIV
MFEGRHQFEEL---PVLRRRGKQKEKGYRHKVPQKILSKWEASVGLAEQYDVPKGSKNRRCVSSSIKLDSEEDMPFEDCT
ND-PESEHDLLLNGCLKSLAFDSEHSADEKEKPCAKSRARKSSDNPKRTSMKKGHMQFEAHK------------------
------EERRGKIPENLGLSFISGDVSDKQASNELSRIANSLTGSNTAPGSFLFSSCGKN-----TAKKEFETSNCDSLL
GLSEGALISKHSEEKKKLQ-------------------------------------------------------------
---RGLMCSSK-VQLCYIG-------------------------------------------------------------
--------------AGDEEKRSDSISICTTSDDGSSD--LDPIDNSSESDNSVLEITDAFDRTENMLSV-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------QKNEKVKYTRYPATNTKVKAKQKSLITNSHTDHLMDCAKTVEPG-TETSQVNLSDLKVSAVVRKPQSD
FRNDSFSPKFNTPSSISSENSLIKSGATNQALLHAKS-KQPKIRSIKCKHKENPVVVEPPVTNEDCSLKCCSSDTK---G
SPLASISKSGKVDGLKLLSNMHEKTRDSNDIETAVVKHVLSELKELSYRSLSEDVSDSGTSKPSKPLLFSSASGQNHIPI
EPDYKFSTLLMMLKDMHDSKTKEQRLMTAQNLVSYRSPGLGDCSSSSPVSASKVLVSGSSTHSSEKNGDGTQKSVRPSPS
G-GDSALSGELSVPVPGLVSDRRD---VPASSKSHSDCVTRRNCGRSKPSSKLRDSFAAQMGRNTLNRKALKTERKRKLS
RLPAVTLEAALQGDRVSGDSENGSSRGGLEDSGKEEPLQLMGHLTSEDS-AHFSSVHFDNKVNHPDPDKIPEKGPSFEN-
--RKGPELDNEMNSEN---DEPSGVNQAVPKKRWQRLNQRRTKPRKRTNRFREKENSEGAFGVLLPSDPVKKG-DEFPEH
RPPTSTNVIEDTLADPNHTSCLDSIGPRLNVCDKSSASVEEMEKEPGIPSLTPQPELPEPAVRSEKKRLRKPSKWLLEYT
EEYDQIFAPKKKQKKVQEQVHKVSSRCEEESLLARCRSS--AQNKQVDENSL-----------ISTKEEPPVLEREAPFL
EGPLAQSELG------GGHAELPQLTLSVPV-APEVSPRPI-------LESEELLVKTPGNYESKRQRKPTKKLLES-ND
LDPGFMPKKGDLGLSKKCYEAGHLENDS-ESRAASR--EYGG--GAAKIFDK-----------------------PRKRK
RQRHATAKVHCKKMKNDDSSKETPG-SEGELMTHRTAASPKETVEESVENDHGMPASKKLQGERGGGAALKENVCQNCEK
LGE--LLLCEAQCCGAFHLECLGLTEMPRGKFICNECRTGIHTCFVCKQSGE------DVKRCLLPLCGKFYHEECVQKY
PPTVMQNKG-FRCSLHICITCHAAN------PASVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTP-
RRGCRNHEHVNVSWCFVCSE-----------------------------------------------------GGSLLCC
DSCPAAFHRECLNI-DIPEG---NWYCNDCKA---------------GKKPHYREIVWVKVGRYR-WWPAEICHPRAVPS
NIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMG--KGVDGTYKKALQEAAARFEELKAQKELRQLQED
RKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATDDNPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFTKRQ
YPEVEIFRTL-QRGWGLRTKTDIKK------------------GEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTL
DKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAG-TELTFNYNLECLGNG-KTVCKCGAPNCSG
FLGVRPKN------QPIATEEKSKKFKKKQQGKRRTQGEITKEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRP
AG-----------KWECPWHQCDI--CGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIRE
YVPPPVPLPPGPGTHLAEH-SSGVAAQGPKMLDKLPADTNQTLSLSKKALAGTCQRPLLP-ERPPDRTDSRPQPVDR---
--VRDLAGSGTKPQSLVSSQKPLDRPPAVAGPRPLLSDKPS-PVTGISSSPSVRS--------QSLERPLGTADPR---L
DKSIGAASPRPQSLEKTPG-------------PPGLRLPPPDRL------------------------------------
------------------------------------------------------LVTSSPKPQTSDRPPD----------
------------------------------------------------------------------------KSHASLSQ
RLPPPDKVLS-------AVVQTLVAKEKALRPVDQNTQS----KNRAALVMDLIDLTPHQKERAASPHEVTPQVDEKMPV
LESSSWTASKGLG----QMPRAVER-GSMSDPVLQPPGKTAVPS-EHPWQAVKSLTQARLLSQPSAK-AFLYEPTTQASG
RAPAGVEQIPGPPSQAPGLVKQVKQ----MTGGQQLPGLAAKSG----QSFRPLGKAPSTLCTEEK-----KLATAEQSP
WALG--KSSPGPGLWPMVAGQTISPSCWSSGNTQTLAQTCWSLGR-----GQD--PKPEQNTLPALNQAPSSHKCAESEQ
K
>Myotis_lucifugus_NSD1
------------------------------------------------------------------MDQTSELPRRNCLL
PFSNPVNLDAPEDKDSPFGNGQSTFSEPLNECTMQLSTAS-GTSQNAYGQDSPSCYIPLRKLQDLASMINVEYLNGSADG
SESFQDPEKSDSRAQSPIVCTSLSPGGPT---------------------------------------------------
------------------------------------------------ALAMKQEPSCNNSPELQVKVTKTVKNGFLHFE
NFTCVDDADVDSEMDPEQPVTEDESIEEIFEETQTNATCNYEPKSENGVDVAMGNEQDSTPESRHGAVKSPFLPLAPQTE
TQKNKQRNEVDGSNEKASLLPAPFSLGDTNVTIEEQLNSVNLSFQDDPDSSTSTLGNMLELPG---TSSSSTSQELPFCQ
PKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMK--VSNRRPY-----RQYYVEAFGDPSERAWVAGKAIV
MFEGRHQFEEL---PVLRRRGKQKEKGYRHKVPQKILSKWEASVGLAEQYDVPKGSKNRKCVSSSIKLDSEEDMPFEDCT
ND-PESEHDLLLNGCLKSLAFDSEHSADEKEKPCAKSRVRKSTDNPKRTCVKKGHMQFETNK------------------
------EERRGKIPENLGINFISGDVSDKQASNELSRIANSLTGASTAPGSFLFSSCAKN-----PAKKEFETSNCDSLL
GLSEGALISKRSGEKKKLQ-------------------------------------------------------------
---RGLVCSSK-VQLCYIK-------------------------------------------------------------
--------------AGDEEKRSDSISICTTSDDGSSD--LDPIDHSSESDNSVLEITDAFDRTENMLSL-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------QKNEKVKYSRYPATNTKVKAKQKSLITSSLTDHLTDCTKTAESG-TETSQVNLSDFKVSTLVRKPQMD
FRNDGFSTKFNTPSSICSENSLIKGGATNQTLLHSKS-KQPKIRSIKCKHKENP-VVEPPVTNEDCSLKCCSSDTK---G
SPLASISKSGKGDGLKLLSNMHEKTRDSNDIETAVVKHVLSELKELSYRSLSEDVSESGTSKPSKPLLFSSASSQNHIPI
EPDYKFSTLLMMLKDMHDSKTKEQRLMTAQNLVSYRSPGLGDCSTSSPLGTSKVLVSGASNHNSEKNGDGTQDPVYPSPS
G-GDSALSGELSASLPGLVSDRRD---LPASGKSRSNCVTRRNCGRSKPS-KLQDAFSGQMGKNTANHRALKTERKRKLN
QVPAVIPEAALPGDRQNAASENGSLGGGAEDPAKEEPLQLMGHLTSEDS-AHFSDVHFDNKVNQSEPDKT-EKGSIFEN-
--RKGPELDSEMNSEN---DEPSGVNQVVPKKRWQRLNQRRTKPRKRTNRFREKENSEGSFGVSLSADSVKKG-GEFPEH
RPSPSTNILEDVLTDPNHTGHLDSVGPLLNVCDKSGANTEEMEKEPGIPTLTPQPELPEPAVRSEKKRLRKPSKWLLEYT
EEYDQIFAPKKKQKKVQEQVHKVSSRCEEENLLARSRSN--AQNKQVDENSL-----------ISTKEEPPVLEREAPFL
EGPLSHSELG------GGHAELPQLTLSVPV-ALEVSPRPP-------LKSEELLVKTPGNYESKRQRKPTKKLLES-ND
LDPGFMPKKGDIGLSKKCYDAGHLENNIAESCGASHSKKFGGVIGTTKIFDK-----------------------PRRRK
RQRHAIAKMHCKRVKNEDSSRETPG-SEGELMTHRMAASLKEAVEEGIENDHGMPASKKLQGERGGGAALKENVCQNCEK
LGE--LLLCEAQCCGAFHLECLGLTEMPRGKFICNECRTGIHTCFVCKQSGE------DVKRCLLPLCGKFYHEECVQKY
PPTVMQNKG-FRCSLHICITCHAAN------PASVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTP-
RRGCRNHEHVNVSWCFVCSE-----------------------------------------------------GGSLLCC
DSCPAAFHRECLNI-DIPEG---NWYCNDCKA---------------GKKPHYREIVWVKVGRYR-WWPAEICHPRAVPS
NIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMG--KGVDGTYKKALQEAAARFEELKAQKELRQLQED
RKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATDDNPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFTKRQ
YPEVEIFRTL-QRGWGLRTKTDIKK------------------GEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTL
DKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAG-TELTFNYNLECLGNG-KTVCKCGAPNCSG
FLGVRPKN------QPIATEEKSKKFKKKQQGKRRSQGEITKEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRP
AG-----------KWECPWHQCDI--CGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIRE
YVPPPVPLTPGPNTHVAEQQSSGVAAQGPKMLDKPPAEANQTLSLSKKTLAGTCQRPPPP-ERPPDRTDSRPQPVER---
--VRTLAGSGAKPQSLVSSQKSLDRPSIVGGPRTQLSDKPS-PVTGPSSSPSVRS--------QPLERPLGAADPR---L
DKSIGAASPRPQSLEKTPV-------------PTVLRLPPSDRL------------------------------------
------------------------------------------------------LVTSSPKPQTSDRSPD----------
------------------------------------------------------------------------KSHTSLTQ
RFPPPDKVLS-------AVVQTLVAKEKALRPVDQNTQS----KNRAALVMDLIDLTSRQKERAASPHEATPQADEKMPV
LESSSWLASKGLG----QMSRAVER-GSVSEPVLQPPGKAVAPL-EHPWQAVKSLTQARLLSPSPAK-AFLYESATQAAG
RAPAGAEQIPGPPSQALGLVKQVKQ----MAGGHQVPGLVAKSG----QSFRPLGKAPSSLSTEEK-----KLATTEQSP
WALG--KTSPGPGLWPMLAGHTLASSCWSSGSTQTLAQTCWSLGR-----GQD--PKPEQNTFPTLNQAPSSHKYAESEQ
K
>Callorhinchus_milii_NSD1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------MDHIC-----------------------------------------------------
-----------------------------EYEFTVG--------------------SSLPFSNQQRFSNSLGFSISE---
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------SSGISYRTGQNDVCG--------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------EECYN-----------------LQERSAVHLSPGFQDSTSPVLNGHGST
SPYIPLR---------------KLQDLASMIPTRFS------------------------------------DSTEAR-Q
WLDSPQDSVTQDCCVTD-KDSCSP--------------------------------------------------------
------------------------------------------SESDSTPEVKLKITKMVMNG------------------
---------------------------------------------KMMFESAICSEVETEDGKGS---------------
---------------------------------DEQSP------------------------------------------
---GIEDRE----------------------APVLP-------VLCHLRSSNRVWDLRERRRLLCDAERVG---------
--LEMVQDFRG------TRELKVEARSSFSSLMAASGSLLVEG----------TRAKAFSMATAEGKRQRKPSKKLLEST
EDYDQLFIPKKKLKPGFDPLHQVCFIPDFVILDIVFDYKHIR--------------------------------------
------------------------LLYLFSITENS---------------------------ERKRHRKPTKKLLES-TG
DFDQFVPKKK-------------------------------------------------------------------FKR
DLYHSFKSDIQP-----------------------------DSADEINDLDPFLSTSRKSQMERGGGAAKKENVCQLCEK
PGE--LLLCEGQCCGAFHLKCLGLTKMPEGKFNCSECTTGFHTCFVCRQNGE------DVKRCLMPLCGKFYHMECIEKY
PTSVALNKG-FRCSLHVCLSCHACN------PTNPRATKGRMMRCVRCPVAYHANDNCLAAGCVVLASNSIICTNHFTA-
RRGCRHHGHVNVSWCFVCSE-----------------------------------------------------GGSLLCC
ESCPAAFHRECLNI-EMPAG---KWYCNDCKA---------------GKKPRYKDIIWVKLGRYR-WWPAEVCHPKNVPT
NIQKMKHEIGEFPVRFFGSNDYFWTYQARVFSYMEGDKGSKDKTC--KGLNSIFKKALQEAAERFEELKAQKETRQAQEE
KRNEKKPPPYKHIKVNKAVGKVQIFTADLSEISRCNCKPTDENPCGQDSECLNRMLMYECHPAVCPAGEKCQNQCFTKRQ
YPEVEILKTP-GRGWGLCCKGDIKK------------------GQFVNEYVGEVIDEEECYSRIKYAQEHDICNFYMLTL
DKDRIIDAGPKGNYSRFMNHSCKPNCETQKWTVNGDTRVGLFALCEILSG-SELTFNYHLECLGTG-KTACKCGAPNCSG
YLGVQPKN------APTSADMKKKPPIPR---KRKQQSELVKDHEEECFRCGDSGQLVICKKPGCPKVYHADCLNLNKRP
AG-----------KWECPWHQCDV--CGKEAISFCELCPSSFCMDHREGALFISKLDGRLSCNEHDPCGPIPLEPGEIRE
IMPSPN---------------------------------------------KLVLHALQPLDSTLIRSIVWDENLLC---
-------------------------------IRIQA--------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Homo_sapiens_NSD2
-------------------------------------------------------------------MEFSIKQ-SPLSV
QSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKA---QLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVFNG
EPGAHDAKLRFESQ-------EMKGIGTP---------------------------------------------------
------------------------------------------------PNTTPIK---NGSPEIKLKITKTYMNGKPLFE
SSICGDSAA------DVSQSEENGQKPENKARRNRKRSIKYDSLLEQGLVEAALVSKISSPSDK----------------
----------------------------------------KIPAKKES-------------------CPN---------T
GRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLK--GQKKSA------RQYHVQFFGDAPERAWIFEKSLV
AFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERK---------------------
---------------------AKFTFLYVGDQLHLNPQVAKEAGIAAES---LGEMAESSGV------------------
------SEEAAENPKSVREEC--IPMKRRRRAKLCSSAETLESHP--DIGKSTPQKTAE---------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------ADPRRGVGSPPGRKKT
TVSMPRSRKGDAAS-QFLVFCQKHRDEVVAEHPDASGEEIEELLRS-------------------------QWSLLSEKQ
RARYNTKFALVAPVQAEEDSG------------------------------NV---------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------NGKKRNHTKRIQDPT
EDAEAEDTPRKRLRTDKH--------------------------------------------------------------
--------------------------------------------------------------SLRK-RDTITDKTARTSS
Y------KAMEAASSLKSQAATKNLS------------------------------------------------DACKPL
KKRNRASTAASSALGFSKSSSPSASLTENEVS-DSPGDEPSESPYESADETQTEVSVSSKKSERG-VTAKKEYVCQLCEK
PGS--LLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVCKESK------TDVKRCVVTQCGKFYHEACVKKY
PLTVFESRG-FRCPLHSCVSCHAS------NPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTA-
RKGKRHHAHVNVSWCFVCSK-----------------------------------------------------GGSLLCC
ESCPAAFHPDCLNI-EMPDG---SWFCNDCRA---------------GKKLHFQDIIWVKLGNYR-WWPAEVCHPKNVPP
NIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGS-RYQGV-RGIGRVFKNALQEAEARFREIKLQREARETQES
ER---KPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKPTDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQ
YPETKIIKTD-GKGWGLVAKRDIRK------------------GEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTI
DKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAG-TELTFNYNLDCLGNE-KTVCRCGASNCSG
FLGDRPKT------STTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRP
FG-----------KWECPWHHCDV--CGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGRSYCCEHDLGAASVRSTKTEKP
PPEPGKPKGKRRRRR-----GWRRVTEGK---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Mus_musculus_NSD2
-------------------------------------------------------------------MEFSIRK-SPLSV
QKVVKCMKMKQTPEILGSANGKTQNCEVNHECSVFLSKA---QLSNSLQEGVMQKFNGHDALPFLPAEKLKDLTSCVFNG
EPGAHDTKLCFEAQ-------EVKGIGTP---------------------------------------------------
------------------------------------------------PNTTPIK---NGSPEIKLKITKTYMNGKPLFE
SSICGDGAA------DVSQSEENEQKSDNKTRRNRKRSIKYDSLLEQGLVEAALVSKISSPADK----------------
----------------------------------------KIPVKKES-------------------CPN---------T
GRDRDLLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHNHTKLK--GQKKSA------RQYHVQFFGDAPERAWIFEKSLV
AFEGEEQFEKLCQESAKQAPTKAEKIKLLKPISGRLRAQWEMGIVQAEEAASMSIEERK---------------------
---------------------AKFTFLYVGDQLHLNPQVAKEAGIVTEP---LGEMVDSSGA------------------
------SEEAAVDPGSVREED--IPTKRRRRTKRSSSAENQEGDP--GTDKSTPPKMAE---------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------AEPKRGVGSPAGRKKS
TGSAPRSRKGDSAA-QFLVFCQKHRDEVVAEHPDASGEEIEELLGS-------------------------QWSMLNEKQ
KARYNTKFSLMISAQSEEDSG------------------------------NG---------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------NGKKRSHTKRADDPA
EDVDVEDAPRKRLRADKH--------------------------------------------------------------
--------------------------------------------------------------SLRKQRETITDKTARTSS
Y------KAIEAASSLKSQAATKNLS------------------------------------------------DACKPL
KKRNRASATASSALGFNKSSSPSASLTEHEVS-DSPGDEPSESPYESADETQTEASVSSKKSERG-MAAKKEYVCQLCEK
TGS--LLLCEGPCCGAFHLACLGLSRRPEGRFTCTECASGIHSCFVCKESK------MEVKRCVVNQCGKFYHEACVKKY
PLTVFESRG-FRCPLHSCMSCHAS------NPSNPRPSKGKMMRCVRCPVAYHGGDACLAAGCSVIASNSIICTGHFTA-
RKGKRHHTHVNVSWCFVCSK-----------------------------------------------------GGSLLCC
EACPAAFHPDCLNI-EMPDG---SWFCNDCRA---------------GKKLHFQDIIWVKLGNYR-WWPAEVCHPKNVPP
NIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGS-RYQGV-RGIGRVFKNALQEAEARFNEVKLQREARETQES
ER---KPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKPTDENPCGSDSECLNRMLMFECHPQVCPAGEYCQNQCFTKRQ
YPETKIIKTD-GKGWGLVAKRDIRK------------------GEFVNEYVGELIDEEECMARIKYAHENDITHFYMLTI
DKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAG-TELTFNYNLDCLGNE-KTVCRCGASNCSG
FLGDRPKT------SASLSSEEKGKKAKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRP
FG-----------KWECPWHHCDV--CGKPSTSFCHLCPNSFCKEHQDGTAFRSTQDGQSYCCEHDLRADSSSSTKTEKP
FPESLKSKGKRKKRR-----CWRRVTDGK---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Callithrix_jacchus_NSD2
-------------------------------------------------------------------MEFSIKQ-SPLSV
QSVVKCIMMKQTPEILGSANGKTPSCEVNRECSVFLSKA---QLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVFNG
EPGAHDAKLRFESP-------EMKGIGTP---------------------------------------------------
------------------------------------------------PHTTPIK---NGSPEIKLKITKTYMNGKPLFE
SSICGDSAA------DVSQSEENGQKPENKARRNRKRSIKYDSLLEQGLVEAALVSKISSPSDK----------------
----------------------------------------KIPAKKES-------------------CPN---------T
GRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLK--GQKKSA------RQYHVQFFGDAPERAWIFEKSLV
AFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERK---------------------
---------------------AKFTFLYVGDQLHLNPQVAKEAGIAAES---SGEMAESSGV------------------
------SEEAAENSKSVREEG--IPMKRRRRAKQCSSAETLESEP--DIVKSTPQKTAE---------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------ADPRRGVGSPPGRKKA
TVSTPRSRKGDAAS-QFLVFCQKHRDEVVAEHPDASGEEIEELLRS-------------------------QWSLLSEKQ
RARYNTKFALVAPVQAEEDSG------------------------------NI---------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------NGKKRNHPKRTQDPT
EDLEAEDTPRKRLRTDKH--------------------------------------------------------------
--------------------------------------------------------------SLRK-RDTITDKTARTSS
Y------KAMEAASSLKSQAATKNLS------------------------------------------------DACKPL
KKRNRASTAASSALGFSKSSSPSASLTENEVS-DSPGDEPSESPYESADETQTEVSVSSKKSERG-VTAKKEYVCQLCEK
PGS--LLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVCKENK------TDVKRCVVTQCGKFYHEACVKKY
PLTVFESRG-FRCPLHSCVSCHAS------NPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTA-
RKGKRHHAHVNVSWCFVCSK-----------------------------------------------------GGSLLCC
ESCPAAFHPDCLNI-EMPDG---SWFCNDCRA---------------GKKLHFQDIIWVKLGNYR-WWPAEVCHPKNVPP
NIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGS-RYQGV-RGIGRVFKNALQEAEARFREIKLQREARETQES
ER---KPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKPTDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQ
YPETKIIKTD-GKGWGLVAKRDIRK------------------GEFVNEYVGEVIDEEECMARIKHAHENDITHFYMLTI
DKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAG-TELTFNYNLDCLGNE-KTVCRCGASNCSG
FLGDRPKT------STTLSSEEKGKKAKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRP
FG-----------KWECPWHHCDV--CGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGRSYCCEHDLGAASVRSTKTEKP
PPEPGKPKGKRRRRR-----GWRRVTEGK---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Rattus_norvegicus_NSD2
-------------------------------------------------------------------MEFSIRK-SPLSV
QKVVKCMKMKQAPEILGSANGKTQNCEVNHECSVFLSKA---QLSNSLQEGVMQKFNGHDALPFLPAEKLKDLTSCVFNG
EPGAHDTKLCFETQ-------EVKGIGTP---------------------------------------------------
------------------------------------------------PNTTPIK---NGSPEIKLKITKTYMNGKPLFE
SSICGDGAA------DMSQSEENGQKSDNKTRRNRKRSIKYDSLLEQGLVEAALVSKISSPEDK----------------
----------------------------------------KIPVKKES-------------------CPN---------S
GRDRDLLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHNHTKLK--GQKKSA------RQYHVQFFGDAPERAWIFEKSLV
AFEGEEQFEKLCQESAKQAPTKAEKIKLLKPISGRLRAQWEMGIVQAEEAASMSVEERK---------------------
---------------------AKFTFLYVGDQLRLNPQVAKEAGIATEP---LGEMVDSSVA------------------
------NEEAAVDPGTMREED--IPVKRRRRAKRSSSAENQEGDP--GTEKSTPPKMAD---------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------AEPKRGVGSPAGRKRS
TGSASRSRKGDSAA-QFLVFCQKHRDEVVAEHPDASEEEIEELLGS-------------------------QWSMLNEKQ
KARYNTKFSLMISAQSEEDSG------------------------------NT---------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------SGKKRTHTKRTDDPP
EDVDVEDAPRKRLRTDKH--------------------------------------------------------------
--------------------------------------------------------------SLRKQRETITDKTARTSS
Y------KAIEAASSLKSQAATKNLS------------------------------------------------DACKPL
KKRNRASATASSALGFNKSSSPSASLTENEVS-DNPGDEPSESPYESADETQTEASVSSKKSERG-MAAKKEYVCQLCEK
TGS--LLLCEGPCCGAFHLACLGLSQRPEGRFTCTECASGIHSCFVCKESK------MEVKRCMVNQCGKFYHEACVKKY
PLTVFESRG-FRCPLHSCMSCHAS------NPSNPRPSKGKMMRCVRCPVAYHGGDACLAAGCSVIASNSIICTGHFTA-
RKGKRHHTHVNVSWCFVCSK-----------------------------------------------------GGSLLCC
EACPAAFHPDCLSI-EMPDG---SWFCNDCRA---------------GKKLHFQDIIWVKLGNYR-WWPAEVCHPKNVPP
NIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGS-RYQGV-RGIGRVFKNALQEAEARFNEIKLQREARETQES
ER---KPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKPTDENPCGSDSECLNRMLMFECHPQVCPAGEYCQNQCFTKRQ
YPETKIIKTD-GKGWGLVAKRDIRK------------------GEFVNEYVGELIDEEECMARIKYAHENDITHFYMLTI
DKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAG-TELTFNYNLDCLGNE-KTVCRCGASNCSG
FLGDRPKT------STSLSSEEKSKKAKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRP
FG-----------KWECPWHHCDV--CGKPSTSFCHLCPNSFCKEHQDGTAFRSTQDGQSYCCEHDLRADSANNTKTEKP
FLDSLKAKGKRKKRR-----CWRRVTDGK---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Equus_caballus_NSD2
MGASLFLISSHPLEFWHFHWLSLTGDCSCTVKTPHHHIAAREVFLKPPPSCTWASCGRRAMLQVVHVVAQQCCP-QLVHL
QKVVKCIKMKQAPEILGNTNGKTQNCEVNRECSVFLSKA---QLSTSLQEGVMQKFNGHDALPFIPTEKLKDLTSRVFNG
EPGAHDARLRFESQ-------EMKGIGTP---------------------------------------------------
------------------------------------------------PNTTPIK---NGSPEIKLKITKTYMNGKPLFE
SSICGDGAA------TVSQSEENGQKPENKARRNRKRSIKYDSLLEQGLVEAALVSKISGPSDK----------------
----------------------------------------KIPAKKES-------------------CPS---------T
GKDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLK--GQKKSA------RQYHVQFFGDAPERAWIFEKSLV
TFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERK---------------------
---------------------AKFTFLYVGDQLRLNPHVAKEAGIAVES---LGEMVESSGV------------------
------TEEAAYNSKPMREEG--IPIKRRRRAKLPSSAENQESDP--GTVKTTPQKTAE---------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------GDSKRGVGSPSGRKKA
TASTPRSRKGDAAS-QFLVFCQKHRDEVVAEHPDASSEEIEELLGS-------------------------QWNMLNEKQ
KARYNTKFALVASSQSEEDSGSSLKSFGEA----KRKVFQDSPKRRPRPRSNL---------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------NGKKRNHTKRTQDPT
EDVEVEDAPRKRLRTDKQ--------------------------------------------------------------
--------------------------------------------------------------GLRK-REMITDKTARTSS
C------KAIEAASSLKSQAATKHLS------------------------------------------------DACKPL
KKRNRASAAASSALAFSKSSSPSASLTENEVS-DGQGDEPLESPYESADETQTEVSVSSKKSERG-VTAKKEYVCQLCEK
TGS--LVLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHTCFVCKENK------TDVKRCVVSQCGKFYHEACVRKY
PLTVFESRG-FRCPLHSCVSCHAS------NPSNPRPSKGKMMRCVRCPVAYHGGDACLAAGCSVIASNSIICTGHFTA-
RKGKRHHAHVNVSWCFVCSK-----------------------------------------------------GGSLLCC
ESCPAAFHPDCLNI-EMPDG---SWFCNDCRA---------------GKKLHFQDIIWVKLGNYR-WWPAEVCHPKNVPP
NIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGS-RYQGV-RGIGRVFKNALQEAEARFREIKLQREARETQEN
ER---KPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKPTDENPCGFDSECLNRMLMFECHPQVCPAGEYCQNQCFTKRQ
YPETKIIKTD-GKGWGLVAKRDIRK------------------GEFVNEYVGELIDEEECMARIKYAHENDITHFYMLTI
DKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAG-TELTFNYNLDCLGNE-KTVCRCGASNCSG
FLGDRPKT------STSLSSEEKGKKTKKKTRRRRTKGEGKKKSEDECFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRP
FG-----------KWECPWHHCDV--CGKPSTSFCHFCPNSFCKEHQDGTAFSSTQDGRSYCCEHDLGAESVRSAKTEKP
FPEPMKSKGKRKKRR-----CWRRVTEGK---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Monodelphis_domestica_NSD2
-------------------------------------------------------------------MNFSIRRNSPSLT
QKIVSQLKMKQVPEILGNTNGKTQNCEVNRECSVFLSKA---QISTTLPEGVMQKFNGHEALPFIPAEKLKDLTSRVFNG
ESGAQDAKLRFESQ-------EIKGIGTP---------------------------------------------------
------------------------------------------------PHTTPIK---NGSPEIKLKITKTYMNGKPLFE
SSICGDNGP------DVSQSEENEQKLENKSRRNRKRSIKYDSLLEQGLVEAALVSKASSPSEK----------------
----------------------------------------KILAKRES-------------------YPN---------I
NKEKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLK--GQKKSA------RQYHVQFFGDAPERAWIFEKSLV
SFEGEEQFEKLCQESAKQAPTKAEKIKLLKPISGKLRTQWEMGIIQAKEAVSMTVEERK---------------------
---------------------AKFTFVYVRDRLHLNPQVAKEAGIAVDP--LEEIE-ESSDM------------------
------SEETAQNLK-HKELG--VPIKRRRRSKLLSCTDNLESDS--GPKNITPQRAAEQ--------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------ADSKRGLGSPVGRKKA
AASTPRSRKGDSGS-QFLVFCQKHRDEVVAEHPDASSEEIEELLES-------------------------QWNMLNEKQ
KARYNTKFAIVTSPKSEEDSGSSLKNIGDT----KRKVFQDSPKRRSRSRSNL---------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------HGKKRNNTKRTQHPT
EDFEVQEPPRKRLRMDKQ--------------------------------------------------------------
--------------------------------------------------------------NNRK-RETSNDKATKTNS
S------KVTETSSSLKNQSATKNLS------------------------------------------------DACKPL
KKRNRASATESSTLAFSKSSSPSTSLTENEIS-DGQGDEPSESPYESADETQTEISISSKKSERG-TTAKKEYVCQLCEK
SGN--LLLCEGPCYGAFHLSCLGLSRRPEGKFICSECTSGIHSCFVCKEKK------TEVKRCVVSQCGKFYHEACVKKY
HLTVFESRG-FRCPLHSCVSCHVT------NPSNPRSSKGKMMRCVRCPVAYHGGDGCLAAGCSVIASNNIVCTNHFTA-
RKGKSHHAHVNVSWCFVCSK-----------------------------------------------------GGSLLCC
ESCPAAFHPDCLNI-EMPDG---SWYCNDCRA---------------GKKLHFQDIIWVKLGNYR-WWPAEVCHPKNVPP
NIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGS-RYQGI-KGIGKVFKNALHEAEARFREIKLQREARETQEN
ER---KPPPYKHIKVNKPCGKVQIYTADVSEIPKCNCKPTDENPCGFDSECLNRMLMYECHPQVCPAGEQCQNQCFTKRQ
YPETKIIKTD-GKGWGLVAKRDIKK------------------GEFVNEYVGELIDEEECMARIKYAHENDITHFYMLTI
DKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAG-TELTFNYNLDCLGNE-KTVCRCGASNCSG
FLGDRPKN------SAALSSEEKGKKTKKKTRRRRTKGEGKKESEDDCFRCGDGGQLVLCDRKCCTKAYHLSCLDLVKRP
FG-----------KWECPWHHCDV--CGKPSVSFCHFCPNSFCKEHQDGTVFSTTQDGRLCCSEHDFGVESIRNPKTEKP
FPEPTKLKPKRKKRR-----CWRRKTECK---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Gallus_gallus_NSD2
-------------------------------------------------------------------MDFSIKRSSQLLT
RKIN-YLKMKQVPEILGNTNGKTQNCEVNRECSVYLGKA---QLSATLQEGVMQKYNGHDALPFIPADKLKDLTSRVFNG
ESGAQDAKLRFEPQ-------EIKGVGTP---------------------------------------------------
------------------------------------------------PNTTPIK---NGSPEIKLKITKTYMNGKPLFE
SSICGDNGA------DVSQSEENEQKTTNKERRNRKRSIKYDSLLEQGLVEAALVSKTSSSPEN----------------
----------------------------------------KAPAKRDS-------------------TQST--------I
KDDKVHLLKYNIGDLVWSKVSGFPWWPCMVSADPILHSYTKLK--GQKKSF------RQYHVQFFGDAPERAWIFEKSLV
PFKGKDQFEQLCQESAKQALTKAEKIKMLKPVPGKLRPQWEIGVKQASEAVGMTVEERK---------------------
---------------------AKYTFIYIRDRPHLNPQVAKEVGIAVEL--LEEEVDESSYS------------------
------NEETSENLKSMKESG--IPNKRRRRTSKLSATDDTQESSQLETKNTTPQKSSEQ--------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------AESKRGIGSPLSRKKT
PASTPRSRKGDAVS-QFLVFCQKHRDEVVAEHPDASSEEIEELLES-------------------------QWNMLSEKQ
KARYNTKFAIVTSPKSEEDSGSSLKNIGEA----KRKVFQDSPKRRSRSRSNL---------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------HGNKRNQKKRTKEPT
EDFEVQEAPRKRLRMDKQ--------------------------------------------------------------
--------------------------------------------------------------NNRK-RETSNDKTAKTNS
T------KVTETSSSQKNQSATKNLS------------------------------------------------DACKPL
KKRNRASAAESSTLAFSKSSSPSASLTENEIF-DGPGDERSESPYESADETQTEVSISSKKSERG-TGTKKEYVCQLCEK
TGD--LLLCEGLCYRAFHVSCLGLSGRPAGKFVCSECTSGVHTCFVCKERK------ADLKRCVVSHCGKFYHEACVKKF
HLTVFESRG-FRCPLHSCLSCHVS------NPSHPRISKGKMMRCVRCPVAYHAGDVCIAAGCAVIASNSIVCTNHFTA-
MKGKSHHAHVNVSWCFVCSK-----------------------------------------------------GGSLLCC
ESCPAAFHPDCLNI-EMPDG---SWYCNDCRA---------------GKKLHFQDIIWVKLGNYR-WWPAEVCHPKNVPP
NIQKMKHEIGEFPVFFFGSKDYFWTHQARVFPYMEGDRGS-RYRGI-KGIGKVFKNALQEAEARFREIKLQREAKETQES
ER---KPPPYKHIKVNKPCGKVQIYTADISEIPKCNCKPTDENPCGFDSECLNRMLMYECHPQVCPAGERCQNQCFTKRE
YPETEIIKTD-GKGWGLVAKRDIKK------------------GEFVNEYVGELIDEEECMARIKYAHENDITHFYMLTI
DKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAG-TELTFNYNLDCLGNE-KTVCKCGAPNCSG
FLGDRPKN------SSTNASEEKGKKTKKRTRRRRTKNEGKKESEDDCFRCGDGGQLVLCDRKSCTKAYHLSCLDLVKRP
FG-----------KWECPWHHCDV--CGKPSVSFCHFCPNSFCKEHQDGTVLNSTLNGQLCCSEHVLGVDSVETQKTEKP
RKKLNKLKPKRKERN-----RWMR-AECK---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Anolis_carolinensis_NSD2
--------------------------------------------------------------------------------
----------------------------------------------------MPKYNGHDALPFIPADKLKDLTSRVFNG
ESGTQDSKLHFESR-------DIKEAGTP---------------------------------------------------
------------------------------------------------PNTTPIK---NGSPEIKLKITKTYMNGKPLFE
SSICGDNGI------EVPQVEESEKKTSNKERRNRKRSNRYDSLLEQDFVEASSVSNASSAENRG---------------
----------------------------------------KKREEKRN-------------------TPN----------
NFTDHHLLRYHIGDIVWSKVSGYPWWPCMISTDPLLHNFTKLN--GQKKSF------RQYHVQFFGDSPERAWVFERSLA
PFKGEEQFEQLCQESAKHSLTKADKIKMLKPVSGKLRPQWEMGVKQAKDALSLTMEERK---------------------
---------------------TKYTFIYIRGRPLLNPQVAKEAGLVVKS----LEEMDKIYT------------------
------DEDISKSLKSRKGHD--IPAKRRRKTKLLVMTESEEDFMHAKNIGMSDKSSNSE--------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------KDLEEGEG------KR
VSGSPISRKGDAVS-QFLVFCQKHRDEVVAEHPEAATDEIEELLES-------------------------QWNMLSEKQ
KARYNTKFAIMTSPKSEEDTG------------------------------NL---------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------HGNKRKPIKRTKKHT
EDFEVEEAPRKRLRMDKR--------------------------------------------------------------
--------------------------------------------------------------NYRK-RERSNDKPEKTYS
S------KVTETSS----QKNQSGLS------------------------------------------------DACKPL
KKRNRASAAESSHLGYSKSSSPSVSLIENEIS-DSLGDERSESPYESADEALAEISQS-KKSDRG-AATKKEYVCQICEK
PGE--LLLCEGRCFGAFHAGCTGLSAKPVGHFICTECSSGIHSCFVCKEKK------PEVKRCIVSHCGKFYHETCVKKF
HLTVFENRG-FRCPLHSCVSCHVT------GPSNPKVSKGKMIRCVRCPIAYHASDACVAAGCAMITSSSIICTNHFTA-
KKGKSHHAHVNVSWCFVCSK-----------------------------------------------------GGSLLCC
ESCPAAFHPDCLNI-EMPDG---SWYCNDCKA---------------GKKIHFQDIIWVKLGKYR-WWPAEVCHPKNIPP
NIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGS-RYQGI-KGIGKVFKNALQDAEARFREIKFQREAKETQEN
ER---KPPPYKHIKVNKPFGKVQVYTADISEIPKCNCKPSDENPCGFDSECLNRMLMYECHPQVCPAGERCQNQCFTKRQ
YPETKIIKTD-GKGWGLIAKRDIKK------------------GEFVNEYVGELIDEEECMARIKYAHENDITHFYMLTI
DKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVHGDTRVGLFAVCDIPEG-TELTFNYNLDCLGNE-KTVCKCGAPNCSG
FLGDRPKN------SSSNASEEKGKKTKR-IRRRKTKNKARKKTEDYCFRCGDGGQLVLCDRKFCTKAYHLSCLDLIKRP
FG-----------KWECPWHHCDV--CGKLSVAFCHFCPNSFCKDHQDDAVLDSNLNGQLFCTDH--IEENFTEKKMKRT
ARKMITLKSKRRQRN-----KWKKQHTCGKL-------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Callorhinchus_milii_NSD2
-----------------------------------------------------------------MAQPCRFIGNPLPLA
QDLLNPISMKQVPEILGIANRKSQNGEMDSEHSLLPDKTAT-QLSAALQDGVMHRLNGHDATSAYRSDKLKDLTALMLNG
DSGAVQEPLSVQASSPVDCSIENRGSETP---------------------------------------------------
------------------------------------------------PHTTPKK---SGSPEIKLRITKTYLNGKPLFE
SSLCGDLQIDDPEIIEHQQNVEEKEENQERRKRKRKRSVKYDALLEQNLAEVALVSKTSNTPDAD---------------
----------------------------------------EKIAKEDL-------------------EEEEERDEETKEK
DKEKDVPVKYNVGDMVWSKVSGYPWWACMISSDPLLNTHTKVK--GLNRAIG-----RQYHVQFFGEAPERAWIFEKSIV
PFEGAQQYDQLIQDCAKHATSKAEKNKLLKPIPAKIRVQWDVGISQAEEALMMTPEDRK---------------------
---------------------AKYTFVYDHDRPLLPPQVAKETGVPVERIEGRKYPAEESLS------------------
------TKENFADSRGSRKRNSSVPNKNRRCSKPSESQKTPTKQCINRTVEPSEGSPSERTVC-----------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------RSSDSESGTGSPMTKRKS
GAPTQRIRKCDTAFAQFMAFCQKHRDELAEEHPDASSEEIEELLES-------------------------QWAMLSDKQ
RARYNTKFSLVTPVTDHKSPAASGFSAASPGATRRKVLQDSPKRTTRSSVSSD---------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------STRQRRLSRKIVDYR
EDSPERIGSNRRLKRDYY--------------------------------------------------------------
--------------------------------------------------------------EDEKYDSNNANQTEASVS
DGIEAGETSSVVNAPQNSQSDISKLS------------------------------------------------DACKPL
KKRSRASTTETLAPAVSKNPSPLTVFTENETSFDGQLESADESADETPTEASSVSSKKSQGERGGSAAAKKESVCQVCEN
AGE--LLFCEGQCCGAFHLTCLGLSKMPQGKFMCSECLSGVHTCFVCKKNG------PDVKRCIVPLCGKFYHEDCVRKY
PPTVFENKR-FRCPLHSCISCHATNAT---NPSNPRVTKGRMMRCVRCPVAYHGGETCIAAGSVVLAANSIICTSHFVP-
KKGYSHHAHVNVSWCFVCSK-----------------------------------------------------GGSLLCC
ESCPAAFHPECLNI-DMPEG---SWYCNDCKA---------------GKKPHYKDIIWVKLGSYR-WWPAEICHPRSVPT
NIQNMKHEIGEFPVHFFGSNDYFWTHRARVFPYMEGDKGC-KDNKI-KGLSKAFKKALQEAGDRFQDLKAQRETREAQEN
ERNGRKPPPYKPIKINKSFGRVQIYTADISEIPRCNCKPTDDNPCGLDSECLNRMLMYECHPSVCPAAGQCQNQCFTKRQ
YPETQVVKTV-GKGWGLISKTGIKK------------------GVFVNEYIGEVIDEDECRARIRFAQEHDIANFYMLTL
DKDRIIDAGPKGNYSRFMNHSCQPNCETQKWTVNGETRVGLFSVCDIPAG-IELTFNYNLDCLGNE-KTICKCGAPNCSG
FLGVRPKT------ASN-GSDDKGKRGKKKIRKRKTKHEGRKEHEDECFRCRDGGQLVLCDRKICSKAYHLSCLSLTKPP
FG-----------KWECPWHHCDV--CGKLSVVFCQFCPNSFCKDHQKETVFKSKLDGRPCCSEHDHCNTAEPLEQCKKM
ETVLSLKDTVKSES------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Danio_rerio_NSD2
--------------------------------------------------------------------MTDSKGGSLPAM
PEPKSPTSMKQLSDSPGGRN---GLVDGITDPTML-MNKAATQLAATPQESVPQMIGSHGHN--HTHEHLKDLTSRLLNG
DTEKIPKLCAAPAG-----QPLLKGVEPV---------------------------------------------------
------------------------------------------------SQHASPPRKTSVSPELTVKITKCVVNLGGKPN
RYEVDYTEEK----AEETDAPLRLPEGVLTSPTARRDRQKKKGMVRKRIPPYPILTHAASSDQSPLLHPTINSNDITIEP
CGLPVESIEHTHGDMPTCVTAFPDEQPLSDCEETVDAQGVDETDDAQG-------------------ENDVKE------S
YTETQSNVHFSVGDVIWTKVSGYPWWPCMITTDPEFNMHFRSK---VNSRTG-----LLYHVQYFGDTPERGYVFEKCIV
TFSGKHQYQSLSRSNQLP-INISGRKR---AVPRKFRQKWEIGVSQAKEALGLLTEERL---------------------
---------------------AKFSFVYEDGKAQLNPHMLQVLEEQRNQ----GLQEEPVQR------------------
------EPQELVSLTPPDSTHSSPTNSSTTSTIPSLFSNPIDSSTSSGKTALPRKARKPS--------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------VKTNRRKQRSSTIEWI
VTEASSAKQMPLTESTVQCEVNTEHKKKGKTNAGKRPYRKKDLLCIDLDLQPKASQKKPRHIRQKFPAAPNSVKKRKIKA
GVSICDTLNTVSTSAGLSEVK-------------------------------A---------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------SAPSTKLWEKEDASS
KGMKKVCKRSRESKQDVTL-------------------------------------------------------------
----------------------------------------------------QPKKKSKLEKDFKKWKCPKAASSAPAAV
PAPRGRRRKTDRDENRKRSKKASK------------------------------------------------EEPPPKAK
RGRKRKEESGRQSFP-ASKKCRPSSYAEPE---------RPDSPSDSTDESHP-----SKKAERT-PGAKKESVCLVCEQ
TGE-DIVTCAGQCYGTYHLHCIG-VERSAEKILCTACSTGVHVCFTCKKSE------GEVRRCCALHCGRFYHEACVRLS
ALTVFENRG-FRCPLHTCLSCHYS------GRAACKATKGKMMRCLRCPVAYHVGDLCVAAGSEMISSSAIVCTNHFRA-
KKGYSHHSHVNVSWCFICSK-----------------------------------------------------GGRLLCC
ESCPAAFHPDCLNI-AMPDG---SWFCNDCRS---------------GKKPKYRDVIWVKLGNYR-WWPAEIRHPKNIPT
NIQHLRHEIGEFPVFFFGSKDYFWTHQGRVFPYMEGDRGS-KYQ-Q-TGIGKVFKNALLDAETRFKEIEMEREAKEAHEN
NK---KPPPFKYIKVNKPCGRVQVYTADISEIPKCNCKPSTERPCSFESECLNRMLLYECHPQVCPAGERCQNQDFTKRL
YPETKIIRTA-GKGWGLISLRDIKK------------------GEFVNEYVGELIDEEECRSRIRHAQENDITHFYMLTI
DKDRIIDAGPKGNYSRFMNHSCQPNCETQKWTVNGDTRVGLFAVCDIPAG-TELTFNYNLDCLGNE-KTVCRCGAPNCSG
FLGDRPKN--------GHTSEPKAKLQKKKPKRKRARNEG-KKSEDECFRCGDGGQLVLCDKKGCTKAYHLSCLDRTKRP
FG-----------RWDCPWHHCDV--CGKNSAAFCQLCPNSFCKAHQEGALRSHPLTGQLCCQEHEDSDIRPQTETAQLP
P----PTKPRKYRRRAEAKTTSKAPLKKRPRKNAEV--------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Takifugu_rubripes_NSD2
---------------------------------------------------------------------MDSKGSSLPSM
PEPANPVSMKQLPEPLSVRK---NGGDMSSDHSML-MDKAAAHLAATLQDSVLQKMASHSHG-NHSHERLKDLTSLVLNG
DQD-TLPKLSTPE------QPLLKSAEVP---------------------------------------------------
------------------------------------------------TTNGTHQHNCSSHSEPELKVTVPQVVTQQPPF
QPSSVNGTSL----ATTTESTVRTPEKREDAKKRRGRPHKEKPQASLRPAPVPAEPLHSVNAKD----------------
----------------------------------------ASGAVGEP-------------------DLKPEA------K
HKESPLLITLSVGDLVWTKVSGYPWWPCMVTTDPNFNSHFKQKQKASSSKTG-----VLYHVQYFGDAPERGYVFEKNTV
PFTGEDQYHDLCQCKKPP-ASRSAHKKMAPSVPRKFRAQWNMGIIQAKEALNMPVEERM---------------------
---------------------ANFLFLYDDKGPRLNPHIMEKLKPEASL----DRDPEFRAQ------------------
------PDLPSQPADPLGDLTAQFSNSTSAEMKGAVSSKEMLHPPAETQDPLSSAAEAQA--------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------DTSQEIKGS----EQT
QSAKKTVRRKKSAAENSSDPVKKKRKTAQSRPTEDAPESFSVT-----------------------------GQGVKKRQ
KKNIPAKQ--RTDS-AAEQDP-------------------------------K---------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------TSPERPLSGEAAVKG
PGLKKRRKINKEAEKEA---------------------------------------------------------------
------------------------------------------------------------------------GSSEENSK
KRRR-NKPEKDATGTQKQQKKAAELL--------------------------------------------TDDQNAEKPK
RKRKRRQDGENQAAASKAKKRRLSPCPDPEVS---GGEERPDSPIDSLDG--------TKKGER-----KKEFVCQSCEK
AGE-DLVPCEGQCCGMFHLQCLG-MMELEDKLLCQECSTGVHSCFHCKKSE------GSVRRCHVPHCGKFYHEACIRLN
PLTVFDNKG-FRCPLHTCLGCCCS------SRTKHKPSKGRLMRCLRCPVAYHAGDLCVAAGSEMVTSTAIICTNHFNA-
KKAYRHHSHVNVSWCFVCSK-----------------------------------------------------GGQLLCC
ESCPAAFHPDCLNI-AMPDG---SWFCNDCRA---------------GKKPKYRDIIWVKLGKYR-WWPAEIHHPRNIPT
NIQHLRHEIGEFPVFFFGSRDYFWTHQGRVFPYMEGDRGS-KYQ-R-TGIGKVFKHALLEAEARFKEIKMKREKKEAQQY
SR---KPPPYKFIKVNKPVGKVQVYAADVSEIPKCNCKPSDERPCGFESECLNRMLQYECHPQVCPSGERCGNQDFTQRL
YPDTKIIKTP-GKGWGLITLRDIKK------------------GEFVNEYIGELIDEEECRARIKYAQENNVTNFYMLTI
DKDRIIDAGPKGNYSRFMNHSCQPNCETQKWTVNGDTRVGLFAICDVPAG-TELTFNYNLDCLGNE-KTACCCGAPNCSG
FLGDRPKN------SNGHAAEPKAKRGKRKYKKRKSEGR--KKSEDECFRCGDGGQLVLCDKKTCTKAYHLSCLNLTKRP
FG-----------RWDCPWHHCDV--CGKNSEAFCQLCPNSFCKCHQEGALRPSPVTGQLCCQEHEELDVPTSPGRDDGS
E----TNTTSPAGTDGRPPKGSNARTKSSKRKAE----------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Tetraodon_nigroviridis_NSD2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------ITLSVGDLVWTKVSGYPWWPCMVTSDPEINCHFKQKQKASSSKTG-----ALYHVQYFGDAPERGYIFEKNMV
PFTGEDQYQDLCQCKKKP-ASRSVHKKMAPSVPRKLRAQWNMGIIQANEALSMSVEERM---------------------
---------------------ANFLFLYDDKGPHLNPHIMEKLKPEPGL----DHGAGLRLQ------------------
------PDHRSPPADPLGDLTAHFSNSTSAALQPQPDAQSTPFTCSCSQDPHAAAASPAD--------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------APQKKRRRS----KQA
QTPQKTARRKKSAAENSSDPVKKRRKSKPSPSAEEAPGSVSAAPSVPGQWEVEPQQSPVRQRGAKSDLLACSGEGVKKRQ
KKSLPDKQ--RTDSTGLLQTK-------------------------------K---------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------LSLRRPLSDDTAEKG
PGVKKRRKMNKEAEKEVR--------------------------------------------------------------
----------------------------------------------------------SVCSDFCSQCVSKAGTSEESGK
KQKR-RRRKLERNATEKPLKNPAD------------------------------------------------DQDAEKPK
RRRKRKQDGENQAPASKAKKRRSSPCPEPEVS---GSEGRPDSPSDSLDG--------TKKGER-----KKEFVCQSCEE
AGE-DLVPCEGQCCGMFHLQCLGVLLEPDDKVLCQECSTGVHSCFHCKKSE------GSVRRCHVPHCGKFYHEACIRLN
PLTVFDNKG-FRCPLHTCLGCCYG------NRTKPKSTKGRLMRCLRCPVAYHAGDLCVAAGSEMVTSAAIICTNHFNA-
KKAYRHHSHVNVSWCFVCSKVP---------------------------------------------------GGRLLCC
ESCPAAFHPDCLNI-AMPDG---SWFCNDCRA---------------GKKPKYRDIIWVKLGKYR-WWPAEIYHPRNIPT
NIQHLRHEIGEFPVFFFGSRDYFWTHQGRVFPYMEGDRGS-KYQ-R-TGIGKVFKHALLEAEARFKEIKMKREKKEAQQY
SR---KPPPYKFIKVNKPVGKVQVYAADISEIPKCNCKPSDERPCGFESECLNRMLQYECHPQVCPSGERCCNQDFTQRL
YPDTKIIKTP-GKGWGLITLRDIKK------------------GEFVNEYIGELIDEEECRARIKYAQENNITNFYMLTI
DKDRIIDAGPKGNYSRFMNHSCQPNCETQKWTVNGDTRVGLFAVCDIPAEGTELTFNYNLDCLGNE-KTVCCCGAPNCSG
FLGDRPKN------SNGHTAEPKAKRGKKKYKKRKSEGK--KKSEDECFRCGDGGQLVLCDKKTCTKAYHLSCLNLTKRP
FG-----------RWDCPWHHCDV--CGKNSEAFCQLCPNSFCKSHQEGALRPSPLTGQLCCQEHEELDVPPGQVTTPLG
V----EAKPLRLHRRASPTKTSFKRPGKPKRSLKV---------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Gasterosteus_aculeatus_NSD2
---------------------------------------------------------------------MESKGSSLPTM
PEPANPISMKQPPESLGVRQ---AGGDMSGDPALLMMDKAAAQLAATLQDGVLQKMAGHSHN-NHGHERLKDLTSRVLNG
DQD-ALPKLCAPE------PPMFKGAEAP---------------------------------------------------
------------------------------------------------ATNGTHQHTCSPHADHEHKATIPQVVQQ-PAF
EPRCANGTSL----STAT------EDAVSAMEPERLMRFFFYSYFKETKVLYFIPLISSL--------------------
-----------------------------------------LQPDFPP-------------------PLKGVD------P
REESAAVVGFSVGDLVWTKVAGYPWWPCMVTTDPEFNNHVKQKQKAANSRMG-----PLYHVQYFGDAPERGYIFEKNMV
TFTGEDQYQELRQGRQQP-ASRVVLKRTAPSVPRKLQAQWNMGVIQAKEACGMSLDERM---------------------
---------------------GNFAFLYDDDGPHLNPCILEKSPKK----------------------------------
-------ALRRGKRHKDAEQNSARENIGERAK---------------------AIEAETV--------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------VPEKKKRRP----RQA
ASPA----KTVGRRNNTSEPVK-KRKPKVASLTADVTEPVPLPLS----------------GWFPVKSPALNGHMWLVKR
QRGFIVVE--QLYSRGSERRR-------------------------------L---------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------QRTKLSSLKRDVKQA
KKLKHRSKSPNESLTLSEV-------------------------------------------------------------
----------------------------------------------------W----NGVKYQHQMDNKHIVDSSEGTDK
KQRR-QKPDGDSKEPKKKKKTTAKLKALLPGKPRAPTSSSKLF-------------------------VFTENQDAEKPE
RSRKRKQDGGNASAPSTAKRRRLTPCPEPEGS---GSEGRPDSPSDSLDG--------TKKGDR-----KKEFVCQTCEQ
AGD-DLVPCEGQCCGMFHLRCLGLSLKPDEKLLCQECSSGVHSCFTCKQSE------GAVRRCHVPHCGRFYHEACIRLS
PLTVFDNKG-FRCPLHACLSCHYG------CRSKQRSTKGRLTRCLRCPVAYHAGDPCVAAGSEMVTSTAIICTNHFNA-
KKGYSHHSHVNVSWCFVCSK-----------------------------------------------------GGQLLCC
ESCPAAFHPDCLNI-AMPDG---SWFCNDCRA---------------GKKPKYRDIIWVKLGKYR-WWPAEIHHPRNIPT
NIQHLRHEIGEFPVFFFGSKDYFWTHQGRVFPYMEGDRGS-KHQ-K-TGIGKVFKNALLEAEARFKQIKLKREAKEAQEN
SR---KPPAYKFIKVNKPVGKVHVYTADVSEIPKCNCKPADERPCGFESECLNRMLQYECHPQVCPSGARCCNRDFTKRL
YPETKIIKTP-GKGWGLISLRDVKK------------------GEFVNEYIGELVDEEECRARIKYAHENNISDFYMLTI
DKDRIIDAGPKGNYSRFMNHSCQPNCETQKWTVNGDTRVGLFAVRDIPAG-TELTFNYNLDCLGNE-KTVCRCGAPNCSG
FLGDRPKN------SSSQTAEAKAKRSKRKYRRRKAEGQ--KKSDDDCFRCGDGGQLVLCGKKTCSKAYHLYCLNLNKRP
FG-----------RWDCPWHHCDV--CGKNSEAFCQLCPNSFCKAHQEGALRSWPPTGQLCCLEHEEQPEGPG-APDPGA
VIAALQATPPAPDAGSRPAK------SSRKAGGVEGK-------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Gasterosteus_aculeatus_NSD1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------FFSLLLSGVHTCFVCKTSGS------GVKRCIIPLCGKFYHNDCILAY
SATQPHNKG-SRCPLHVCLSCHITN------PLNICSTKGRLARCVRCPVAYHANDNCMAAGSLVLANNSFLCPNHFTP-
RKGCKNHEHINVSWCFVCSE-----------------------------------------------------GGSLLCC
EACPAAFHQECLNI-EMPQG---SWFCNDCKA---------------GKRPRIKDILWVKWGRYR-WWPAEVCLTRDVPD
NILRMKHEVGEFPVQFFGSKDFVWTYQARVFPYMEGDTHNIEKMG--KGADAIYKNALTDAAERFRELKAEKEMKQLQED
RKNDKKPPPYKHIKVNRPIGKVQIFTADLSEIPRCNCKASDENPCGIDSECINRMLMYECHPQVCVAGERCQNQAFTKRQ
YTPVEIFRTL-SRGWGLVGVSDIKK------------------GAFVSEYVGEVIDEEECRARIRHAQENDISNFYMLTV
DKDRIIDAGPKGNQARFMNHCCQPNCETQKWTVNGDTRVGLFALQDIPKG-VELNFNYNLECLGNG-KTACKCGAPNCSG
FLGVRPKN------QPSAEKLK--EGKRKVPMKKKTKQEVTKEREDECFSCGDGGQIVSCKKPGCPKVYHADCLNLAKRP
AG-----------RWECPWHQCDV--CGKEAASFCEMCPSSYCKEHREGMLFISKLDGKLSCSEHD--------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Oryzias_latipes_NSD2
---------------------------------------------------------------------MDGKGSSLPSM
PEPANPVSMKQPPESLSVRK---ALGDVTSDPALL-MDKAAAQLAATLQDGVLQKMAGHNH---HTHEKLKDLTALVLNG
DQDAVLPQLCAPE------PPMFKGAEAP---------------------------------------------------
------------------------------------------------TATGPHQLNGTAHAEPELTVSVPQVVQQ-PSL
EPYCANGVGL----VTEDT--LSGPDGRHEVKKRRGTANKPKAQVNSTFVLPVDHENTGE--------------------
-----------------------------------------EPAVAQP-------------------ALMSAL------P
GGECPSRTRFCPGDVVWTKVSGYPWWPCMVTNDPEFNSHFKEKQKAVTCELD-----ILYHVQYFGDAAERGYVFERNMV
SFSGEEQYPELCQGIRLP-GSCVTHRKTSASVPQKLQAQWNMGVIQAKEALCMPPDERL---------------------
---------------------ENFGFLYNEEGPQLNPHILEKLKPE----------------------------------
-------DCDDGVLDGQARLLSD-PNSSSSSD---------------------SLAEP----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------VAQKKRRRP----RQA
QTKAD-KRKSKCAASRTRDPVKTKRKPKLPSSTEDRLG--------------------------------------TVRR
ERRKRSKR--PQAGAAADRDQ-------------------------------P---------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------PRRRRSALKDPEKQA
S-------------------------------------------------------------------------------
-------------------------------------------------------------------------TSEGPNK
RRRK-TRDGGEAR--KRADKSQPRLQ---------------------------------------------EDQSTEKPK
RRRKRKQDG--EMKTSKAKKRRSSPCPDAEGS---GSEERPDSPSDSLDG--------TKKGEK-----RKEFVCQVCEQ
AGE-DLVPCEGQCCGMFHLHCLGPSFKPEDKLLCQQCRAGIHSCFACKQSE------GEVRRCHVVHCGKFYHEACIRLN
PLTVFDNKG-LRCPLHACLSCHYG------SRTKHKSTKGRLMRCLRCPVAYHVGDLCVAAGSEMITNTAIVCTNHFNA-
KKGYSHHSHVNVSWCFVCSK-----------------------------------------------------GGQLLCC
ESCPAAFHPDCLNI-AMPDG---SWYCNDCRA---------------GKKPRYRDIIWVKLGTYR-WWPAEIQHPRNIPT
NIQHLRHEIGEFPVFFFGSRDYFWTHQGRVFPYMEGDRGS-KHQ-R-TGIGRVFKNALLEAEARFKEMKMKREAKEAQES
SR---KPPPYKFIKVNRPYGRVQVYTADVSEIPKCNCKPTDERPCGFESECLNRMLQYECHPQVCPSGERCCNQDFTKRL
YPETKIIKTP-GKGWGLVALRDIKK------------------GKFVNEYIGELIDEEECRARIKYAHENNITNFYMLTI
DKDRIIDAGPKGNYSRFMNHSCQPNCETQKWTVNGDTRVGLFAVCHIPAG-TELTFNYNLDCLGNE-KTICRCGAPNCSG
FLGDRPKN------SNGHAAEPKGKRPKRKYKKRRSEGK--KKSEDECFRCGDGGQLVLCDKKTCTKAYHLSCLNLTKRP
FG-----------RWDCPWHHCDV--CGKNSEAFCQLCPNSFCKAHQEGGLWPRPPGGELCCLEHDELEGANGPAHDPGS
VGGAAAPAPLSRSRGSRKADRPGGRTKSSKRKAAEA--------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Lepisosteus_oculatus_NSD2
-------------------------------------------------------------------MDLNAKGSSLPLM
PEHLSPVSMKQAPEALSSRKSQAAGVEMSADPAILMDKAAAAQLVATLQDTVIQISG----------ERLKDLTSRVLNG
DQD-KLPKLCAAEP-----PPLLKGGDPP---------------------------------------------------
------------------------------------------------TPHASPPKKGD-SPEIKLKITKTVANGKPRFE
SCFCEDGEVP----AAAAAPAAQKRKERENKGRKRRRRLVRAEPRRRPLLAPAASSPASVASGSGAGTACKVG-------
---------------------------------HSSFSTPPLASSSVS-------------------PVQEPL------K
DSEGELPGKFSVGDVVWTKVSGYPWWPCMVTKDQALSSHIKLK--AVNSRTS-----VQYHVQFFGNAPEHGYIFEKSIV
PFGGEQQYRELCQESARPCAARSDKKKLPKSVPAKLRAQWEIGITQAKEAAGMETRERL---------------------
---------------------AKFTFAYVNGRPQLSPRVLGELGLEE-R----DPAALPRAC------------------
------QESAALPPEPPGPPAAPHRRSTSWTKR----------TPTIKAPGRIRAGKGRQ--------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------WPLKKRKEVS---TVS
KQKEDQAQPDDQAVAESLDVSKENGKDSLAPKLKGRRGRRRLHPR----------------------------PAVKKAQ
LEDAFVEVSLSESSAPLGPGR-------------------------------R---------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------VRKTKPCAHRELRKK
SDLIGSPKSTHPKRLGKR--------------------------------------------------------------
---------------------------------------------------------PLDDTEVDKVEQPRKRARLNSST
PQRKTRKSKLLAETTERAVESAPAPRTSR-----------------------------------------WGSKPLEQRQ
PAKKRKRASAGRPSLSPASK-RPSPAAAHTES---SGEERPVSPCESTDDAPPGTSASVKRAERG-SAAKKDNVCQVCEL
PGE-ALLLCEGQCCGAFHPRCVGLKEKPPGKFLCQECTTGVRPCFSCKQAA------GELKRCAVPQCGRFYHEACVRQS
ALTVFENKG-FRCPLHVCLSCHVS------HPSRLKAKKGKMLRCVRCPVAYHAGDQCIAAGCELLTSSSIICTNHFTA-
KKGYSHHTHVNVSWCFVCSK-----------------------------------------------------GGSLLCC
ESCPAAFHPDCLNI-GMPDG---SWYCNDCKA---------------GKKPKYRDIIWVKLGSYR-WWPAEIRHPRGIPT
NIQHLRHELGEFPVFFFGSKDYFWTHQARVFPYMEGDRGS-KYQ-R-NGIGKVFKNALLEAEMRFKEIKMEREAKEAQEN
DR---KPPPYKYIKVNKPCGKVQIRTADISEIPKCNCKPVDEKPCGFESECLNRMLMYECHPAVCPAGASCQNQGFTKRQ
YPETKIIKTA-GKGWGLVAKRDIKK------------------GEFVNEYVGELIDEEECRARIKYAQENDITHFYMLTI
DKDRVIDAGLKGNYSRFMNHSCQPNCETQKWTVNGDTRVGLFAVCDIPAG-TELTFNYNLDCLGNE-KTVCRCGAPNCSG
FLGDRPKN------APSGASEDKGKKAKKKLRRRRARHEG-KKSEDECFRCGDGGQLVLCDKKGCTKAYHLSCLDLTKRP
FG-----------RWDCPWHHCDV--CGKNSVAFCQLCPNSFCKAHQEGALRPWGTSGQLCCQEHEDQELHPSLDRKEAE
A----ERPPADRQRPAKNSKKA----------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Latimeria_chalumnae_NSD2
-------------------------------------------------------------------MDLSAKGSSLLLK
QELLNPISMKPAAGILGSANGKTQNGEMNPDPAVLIDK-----VAATLHEGVITKLNSHDALPFLQADKLKNLTSRVLNG
DSETQESKLAADAQ-------EVMGTRTP---------------------------------------------------
------------------------------------------------PHNTPKK---SGSPEIKLKITKTYMNGKPLFE
SSICGDGEAG-----ETELPVEKDLITESKEKRVRKKSLKYDALLEQSLAEAALEVKTSNASQK----------------
----------------------------------------EEKVKSIS-------------------CEN----------
-DGEDQTPKYGIGAIVWSKVSGYPWWPCMVSADPLLNSHFRIK--GQNRTF------RQYHVQFFGDAPERAWICEKGIV
PYEGQEQFEQLCQESIKQA-AKTEKNKLRKTVPAKWRAQWDIGLTQAEEAKEMTVEDRK---------------------
---------------------AKYTFVYVKDHPRLNPQVAMKMGIPVEP---LEDFSETSES------------------
------LASATCQEKGKRDSR--ASREKRRASKPSASSRRRSTSS-------------ER--------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------TDSESPVVSPVSKKRG
GVSTPRSKKGDAAMTQFLVFCQKHRDEVVAEHPDASGEEIEELLES-------------------------QWNMLSEKQ
RARYNTKFSIVTP-RVEPNSP------------------------------ER---------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------NSAKGKQRKRPLEVT
EDTATQEAPKKRLRHDSQ--------------------------------------------------------------
--------------------------------------------------------------NQNK-GKHSKPKSSADSG
A------KATETVASLNKQSAISKLA------------------------------------------------DACKPL
KKRNRSSAAESPAP--SKSSSPSNTLTENETPSEGHGDERSDSPYESADETQTEVSVSSKKSERGAAAAKREFVCQICET
TGE--LLHCEGQCFGVFHLNCLGLSEKPRGKFVCRECTSGVHTCFACKKND------ADVKRCIAPQCGKFYHEECVKKY
QSTMFESKG-FRCPFHTCVSCQAA------YPTNPRATKGKMVRCIRCPVAYHGGDLCIAAGCAILTANSIICTNHFRA-
NKGKSHHSHINVSWCFVCSK-----------------------------------------------------GGSLLCC
ESCPAAFHPDCLNI-EMPDG---SWYCNDCRA---------------GKKPRYQDIVWVKLGNYR-WWPAEVCHPKNVPA
NIQKMKHDIGEFPVFFFGSKDYYWTHQARIFPYMEGDRGS-KHQ-T-KGIGKVFKNALKEAEARFLEVKLQRETKEAQEN
ER---KPPPYKYIKVNKPCGKVQIHTADISEIPKCNCKPTDENPCGLDSECLNRMLMYECHPAVCPAGERCQNQCFTKRQ
YPETKIIKTE-GKGWGLISKRDIKK------------------GEFVNEYVGELIDEEECRARIKHAHENDITHFYMLTI
DKDRIIDAGPKGNYSRFMNHSCQPNCETQKWTVNGDTRVGLFAVCDIPKE-TELTFNYNLDCLGNE-KTVCRCGAPNCSG
FLGDRPKN------ASTNNADDKGKKAKKKPKKRKSKSEGKKEYEDECFRCGDGGELVLCDRKSCTKAYHLSCLDLTKRP
FG-----------KWECPWHHCDV--CGKPSVTFCHFCPNSFCKEHQEGVLFRSAVEGQMCCSEHDLDVDNTREPQTTLQ
ETSNLLPKKSRANNR--------AQTDHT---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Myotis_lucifugus_NSD2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------ESPDESADETQTEVSVSSKKSERG-LTARKEHVCQLCEK
PGR--LLLCEGACCGAFHLSCLGLPRPPEGGFVCSECVSGIHSCFVCKEST------ADAKRCSVPQCGKFYHEACVRRF
PLTVFEGRG-FRCPLHGCVSCHAS------HPSSSRATKGKMMRCLRCPVAYHGGDACLAAGCLVVSSHSIVCTAHFTA-
RKGKRHHAHVNVSWCFVCSK-----------------------------------------------------GGSLLCC
ESCPAAFHPDCLSI-DMPDG---SWFCNDCRA---------------GKRLHHQDIVWVKLGNYR-WWPAEVCHPKNVPP
NIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGS-RYQGV-SGIGRVFKNALQEAEARFREIKLQREARETQES
ER---KPPPYKHIKVSARAG-GGVWGAPSPAAPRCTCLP--ACPASLSGALLHEHEG--CGQPVCQLSRRRDSYCHRTRP
P-------AP-G-GLQPVLR---PQ------------------GEFVNEYVGELIDDEECRARIKHAQENDITHFYMLTI
DKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAMCDIPAG-TELTFNYNLDCLGNE-KTVCRCGAPNCSG
FLGDRPKT------STVLSSEEKGKKTKKKSRRRRTKGEGKKESEDECFRCGDGGQLVLCDRKSCTKAYHLSCLGLGKRP
FG-----------KWVCPWHHCDV--CGKPSASFCHLCPNSFCKEHQDGTTWRSTADGRSYCCEHDSGAEAQS------P
FPAPRRPQGRRRR-------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Canis_lupus_familiaris_NSD2
--------------------------------------------------------------------------------
--------MKQAPEILGNTNGKTQNCEVNRECSVFLSKA---HLSTSLQEGVMQKFNGHDALPFIPSEKLKDLTSRVFNG
EPGAHDAKLRFESQ-------EGKGLGTP---------------------------------------------------
------------------------------------------------PNTTPIK---NGSPEIKLKITKTYMNGKPLFE
SSICGDGAA------AVSQSEENGQKAENKARRSRKRSIKYDSFLEQGLVEAALVSKISSPSDK----------------
----------------------------------------KIAAKKES-------------------CPN---------T
GRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHNYTKLK--GQKKSA------RQYHVQFFGDAPERAWIFEKSLV
AFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSIEERK---------------------
---------------------AKFTFLYVGDQLHLNPHVAKEASIAVES---PAQVVESSGV------------------
------IEEAADNPKSLREEG--IPIKRRRRAKLSGSAENQESEP--GTVKSTPQKVAE---------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------ADPKRGVGCPPGRKKS
VASTPRSRKGDAAS-RFLVFCQKHRDEVVAEHPDASGEEIEELLGS-------------------------QWDMLNEKQ
KARYNTKFALVASSQSEEDSG------------------------------NI---------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------NGKKRIHTKRTQEPT
EDADGEDAPRKRLRTDKH--------------------------------------------------------------
--------------------------------------------------------------GLRK-RETINDKTARTSS
C------KAIEAASSLKSQAATKHLS------------------------------------------------DACKPL
KKRNRASTAAS-STPFSKSSSPSASLTENEVS-DGPGDEPLESPYESADETQTEVSISSKKSERG-VTAKKEYVCQLCEK
TGS--LVLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVCKESK------TDVKRCVVSQCGKFYHEACVRKY
PLAVFESRG-FRCPLHSCVSCHAS------NPSNPRPSKGKMMRCVRCPVAYHGGDACLAAGCSVIASNSIICTGHFTA-
RKGKRHHAHVNVSWCFVCSK-----------------------------------------------------GGSLLCC
ESCPAAFHPDCLNI-DMPDG---SWFCNDCRA---------------GKRLHFQDIIWVKLGNYR-WWPAEVCHPKNVPP
NIQNLKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGS-RYQGV-RGIGRVFKNALQEAEARFREIKLQREARETQEN
ER---KPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKPTDENPCGFDSECLNRMLMFECHPQVCPAGEYCQNQCFTKRQ
YPETKIIKTD-GKGWGLVAKRDIRK------------------GEFVNEYVGELIDEEECMARIKYAHENDITHFYMLTI
DKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAG-TELTFNYNLDCLGNE-KTVCRCGASNCSG
FLGDRPKT------SASLSSDEKGKKTKKRTRRRRTRGEGKKESEDECFRCGDGGQLVLCDRKSCTKAYHLSCLGLGKRP
FG-----------KWECPWHHCDV--CGKPSTSFCHFCPNSFCKEHQDGTAFSSTQDGRSYCYEHDLGAESARSTKTEKP
FPEPMKSKGKRKKRR-----CWRRVTEGK---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Felis_catus_NSD2
--------------------------------------------------------------------------------
--------MKQAPETLGSTNGKTQNCEVNRECSVFLSKA---QLSTSLQEGVMQKFNGHDALPFIPSEKLKDLTSRVFNG
EPGAHDARLRFESQ-------EVKALGTP---------------------------------------------------
------------------------------------------------PSTTPIK---NGSPEIKLKITKTYMNGKPLFE
SSICGDGAA------AVSQSEEHGQKPENKARRNRKRSIKYDSLLEHGLVEAALVSRISSPSDK----------------
----------------------------------------KVAAKKES-------------------CPN---------T
GRDKDHLLKYSVGDLVWSKVSGYPWWPCMVSADPLLHNYTKLK--GQKKSA------RQYHVQFFGDAPERAWIFEKSLV
AFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWETGIVQAEEAASMSVEERK---------------------
---------------------AKFTFLYVGERLHLNPHVAKEAGVSVEAP-PLGPMVEPSGV------------------
------PEEAAADPKSMREEG--VPIKRRRRGKLSSSAENRAGDP--GTVQSTPQKMAE---------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------ADPKRGVGSPPGRKKA
TASAPRSRKGDAAS-QFLVFCQKHRDEVVAEHPDASAEEVKELLGS-------------------------QWDMLNEKQ
KARYNTKFALVASPQSEEDSG------------------------------NV---------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------NGKKRNHTKRTQDPP
EDVEIEDAPRKRLRTDKH--------------------------------------------------------------
--------------------------------------------------------------GLRK-RETASDKTARTGS
C------KAMEAATSLKSQAATKHLS------------------------------------------------DACKPL
KKRNRASAAASCAP-FSKSSSPSASLTENEVS-DGPGDEPAESPYESADETQTEASVSSKKSERG-VAAKKEYVCQLCEK
PGS--LLLCEGPCCGAFHLACLGLARRPEGRFTCSECASGIHSCFVCKESK------TDVRRCVVSQCGKFYHEACVRKY
PLTVFESRG-FRCPLHSCVTCHAS------NPSNPRPSKGKMMRCVRCPVAYHGGDACLAAGCSVIASHSIICTSHFTA-
RKGKRHHAHVNVSWCFVCSK-----------------------------------------------------GGSLLCC
ESCPAAFHPDCLSI-EMPDG---SWFCNECRA---------------GKKLHFQDVVWVKLGNYR-WWPAEVCHPKNVPP
NIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGS-RYQGV-RGIGRVFKNALQEAEARFREIKLQREARETQES
ER---KPPPYKHIKVNKPYGKVQIHTADISEIPKCNCKPTDENPCGFDSECLNRMLMFECHPQVCPAGEYCQNQCFTKRQ
YPETKIIKTD-GKGWGLVAKRDIRK------------------GEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTI
DKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAG-TELTFNYNLDCLGNE-KTVCRCGASNCSG
FLGDRPKT------STSLSSEEKGKKSKKRTRRRRTRGEGKKESEDECFRCGDGGQLVLCDRKSCTKAYHLSCLGLGKRP
FG-----------KWECPWHHCDV--CGRPSTSFCHFCPNSFCKEHQDGAALGSTRDGRPCCCEHDLGAVSARSAQTGKP
FPEPSKSKGKRKRRSEEPAPGVVIVTVL----------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Bos_taurus_NSD2
-------------------------------------------------------------------MEFSVRK-SPLSA
PKVVKCVKMKQAPEVLGSANGKTPSCDVSRECSVFLSKA---QLSAGLQDGVVQKFNGHDALPFIPAERLKDLTSRVFNG
EPGAHDAKLRFESQ-------EVKGLGTP---------------------------------------------------
------------------------------------------------PHTTPVK---NGSPEIKLKITKTYMNGKPLFE
SSICGDGAA------AVSHSEADGQRPEYKARRSRKRSAQRGPVLEHGLGEAALASRLSSPVDK----------------
----------------------------------------KIPVKRES-------------------CPN---------S
SRDKGQLLKYDVGDLVWSKVSGYPWWPCMVSADPLLHSHTRLK--GQKKSA------RQYHVQFFGDAPERAWIFEKSLV
AFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGLVQAEAAARMAVEERK---------------------
---------------------AKFTFLYVGDQLRLNPHVAKEAGVAVES---LGEAAEPSGV------------------
------EEEAADSPKSSGEEG--APVKRRRRAKLSSSTENLPGDP--GPGRATPQKVAE---------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------ADSRRGAGSPPGRKKA
AASTPRSRRGDAAS-QFLVFCQKHRDEVVAEHPDASAEEIEELLAS-------------------------QWNMLNEKQ
KARYHTKFALVAPPQSEEDSG------------------------------NL---------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------NGKKRSHTKRTQGLR
GDAEVEEAPRKRLRTDRH--------------------------------------------------------------
--------------------------------------------------------------GLRK-RETITDKTARTTS
C------KALEAASSLKSQAATKHLS------------------------------------------------DACKPL
KKRHRAPAAAATTLTFSKSSSPSASLTENEVS-DGPGDEPPESPDESADETQTEASVSSKRSERG-ATARKEHVCQLCEE
PGS--LVLCEGPCCGAFHLACLGLSRRPEGRLLCGECTSGIHSCFVCKESK------SDVKRCVVSQCGKFYHEACVRRF
PLTVFESRG-FRCPLHSCLSCHAS------NPSNPRPSKGKMLRCVRCPVAYHGGDACLAAGCSVIASNSIICTNHFTA-
RKGKRHHAHVNVSWCFVCSK-----------------------------------------------------GGSLLCC
ESCPAAFHPDCLSI-EMPDG---SWFCNDCRA---------------GKKLHFQDIIWVKLGNYR-WWPAEVCHPKNVPP
NIQKMKHEVGEFPVFFFGSKDYYWTHQARVFPYMEGDRGS-RYQGV-RGIGRVFKNALQEAEARFREIKLQREARETQES
ER---RPPPYKHIKVNKPYGKVQVHTADISEIPKCNCKPTDENPCGSDSQCLNRMLMFECHPQVCPAGESCQNQCFTKRQ
YPETKIVRTD-GKGWGLVAKRDIRK------------------GEFVNEYVGELIDEEECMARIKRAHENDITHFYMLTI
DKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAG-TELTFNYNLDCLGNE-KTVCRCGASNCSG
FLGDRPKT------SAPLSSEEKGKKTKKKARRRRTKGEGKKPSEDECFRCGDGGQLVLCDRKSCTKAYHLPCLGLGKRP
FG-----------KWECPWHHCDV--CGKPSTAFCHFCPNSFCKDHQDTAAFSSTQDGRLYCSEHDFRAEPARSAQTEQP
CPGPSKAKGRRRRRR-----CWRRVMEGE---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Pan_troglodytes_NSD2
-------------------------------------------------------------------MEFSIKQ-SPLSV
QSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKA---QLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVFNG
EPGAHDAKLRFESQ-------EMKGIGTP---------------------------------------------------
------------------------------------------------PNTTPIK---NGSPEIKLKITKTYMNGKPLFE
SSICGDSAA------DVSQSEENGQKPENKARRNRKRSIKYDSLLEQGLVEAALVSKISSPSDK----------------
----------------------------------------KIPAKKES-------------------CPN---------T
GRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLK--GQKKSA------RQYHVQFFGDAPERAWIFEKSLV
AFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERK---------------------
---------------------AKFTFLYVGDQLHLNPQVAKEAGIAAES---LGEMAESSGV------------------
------GEEAAENPKSVREEC--IPMKRRRRAKLCSSAETLESHP--DIGKSTPQKTAE---------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------ADPRRGVGSPPGRKKT
TVSMPRSRKGDAAS-QFLVFCQKHRDEVVAEHPDASGEEIEELLRS-------------------------QWSLLSEKQ
RARYNTKFALVAPVQAEEDSG------------------------------NV---------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------NGKKRNHTKRIQDPT
EDAEAEDTPRKRLRTDKH--------------------------------------------------------------
--------------------------------------------------------------SLRK-RDTITDKTARTSS
Y------KAMEAASSLKSQAATKNLS------------------------------------------------DACKPL
KKRNRASTAASSALGFSKSSSPSASLTENEVS-DSPGDEPSESPYESADETQTEVSVSSKKSERG-VTAKKEYVCQLCEK
PGS--LLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVCKESK------TDVKRCVVTQCGKFYHEACVKKY
PLTVFESRG-FRCPLHSCVSCHAS------NPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTA-
RKGKRHHAHVNVSWCFVCSK-----------------------------------------------------GGSLLCC
ESCPAAFHPDCLNI-EMPDG---SWFCNDCRA---------------GKKLHFQDIIWVKLGNYR-WWPAEVCHPKNVPP
NIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGS-RYQGV-RGIGRVFKNALQEAEARFREIKLQREARETQES
ER---KPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKPTDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQ
YPETKIIKTD-GKGWGLVAKRDIRK------------------GEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTI
DKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAG-TELTFNYNLDCLGNE-KTVCRCGASNCSG
FLGDRPKT------STTLSSEEKGKKTKKKMRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRP
FG-----------KWECPWHHCDV--CGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGRSYCCEHDLGAASVRSTKTEKP
PPEPGKPKGKRRRRR-----GWRRVTEGK---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Gorilla_gorilla_NSD2
-------------------------------------------------------------------MEFSIKQ-SPLSV
QSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKA---QLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVFNG
EPGAHDAKLRFESQ-------EMKGIGTP---------------------------------------------------
------------------------------------------------PNTTPIK---NGSPEIKLKITKTYMNGKPLFE
SSICGDSAA------DVSQSEENGQKPENKARRNRKRSIKYDSLLEQGLVEAALVSKISSPSDK----------------
----------------------------------------KIPAKKES-------------------CPN---------T
GRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLK--GQKKSA------RQYHVQFFGDAPERAWIFEKSLV
AFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERK---------------------
---------------------AKFTFLYVGDQLHLNPQVAKEAGIAAES---LGEMAESSGV------------------
------SEEAAENPKSVREEC--IPMKRRRRAKLCSSAETLESHP--DIGKSTPQKTAE---------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------ADPRRGVGSPPGRKKT
TVSVPRSRKGDAAS-QFLVFCQKHRDEVVAEHPDASGEEIEELLRS-------------------------QWSLLSEKQ
RARYNTKFALVAPVQAEEDSG------------------------------NV---------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------NGKKRNHTKRIQDPT
EDAEAEDTPRKRLRTDKH--------------------------------------------------------------
--------------------------------------------------------------SLRK-RDTITDKTARTSS
Y------KAMEAASSLKSQAATKNLS------------------------------------------------DACKPL
KKRNRASTAASSALGFSKSSSPSASLTENEVS-DSLGDEPSESPYESADETQTEVSVSSKKSERG-VTAKKEYVCQLCEK
PGS--LLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVCKESK------TDVKRCVVTQCGKFYHEACVKKY
PLTVFESRG-FRCPLHSCVSCHAS------NPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTA-
RKGKRHHAHVNVSWCFVCSK-----------------------------------------------------GGSLLCC
ESCPAAFHPDCLNI-EMPDG---SWFCNDCRA---------------GKKLHFQDIIWVKLGNYR-WWPAEVCHPKNVPP
NIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGS-RYQGV-RGIGRVFKNALQEAEARFREIKLQREARETQES
ER---KPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKPTDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQ
YPETKIIKTD-GKGWGLVAKRDIRK------------------GEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTI
DKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAG-TELTFNYNLDCLGNE-KTVCRCGASNCSG
FLGDRPKT------STTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRP
FG-----------KWECPWHHCDV--CGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGRSYCCEHDLGAASVRSTKTEKP
PPEPGKPKGKRRRRR-----GWRRVTEGK---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Macaca_mulatta_NSD2
-------------------------------------------------------------------MEFSIKQ-SPLSV
QSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKA---QLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVFNG
EPGAHDAKLRFESQ-------EMKGIGTP---------------------------------------------------
------------------------------------------------PNTTPIK---NGSPEIKLKITKTYMNGKPLFE
SSICGDSAA------DVSQSEENGQKPENKARRNRKRSIKYDSLLEQGLVEAALVSKISSPSDK----------------
----------------------------------------KIPAKKES-------------------CPN---------T
GRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLK--GQKKSA------RQYHVQFFGDAPERAWIFEKSLV
AFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERK---------------------
---------------------AKFTFLYVGDQLHLNPQVAKEAGIAAES---FGEMAESSGV------------------
------GEEAAENPKSAREEG--VPMKRRRRAKLCSSAETLESDP--DVVKSTPQKTAE---------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------ADPRRGVASPPGRKKT
TASTPRSRKGDAAS-QFLVFCQKHRDEVVAEHPDASGEEIEELLRS-------------------------QWSLLSEKQ
RARYNTKFALVAPVQAEEDSG------------------------------NV---------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------NGKKRNHTKRTQDPT
EDVEVEDTPRKRLRTDKH--------------------------------------------------------------
--------------------------------------------------------------SLRK-RDTITDKTARTSS
Y------KAMEAASSLKSQAATKNLS------------------------------------------------DACKPL
KKRNRASTAASSALGFSKSSSPSASLTENEVS-DSLGDEPSESPYESADETQTEVSVSSKKSERG-VTAKKEYVCQLCEK
PGS--LLLCEGPCCGAFHLACLGLSRRPEGRFTCSEW---IHSCFVCKESK------TDVKRCVVTQCGKFYHEACVKKY
PLTVFESRG-FRCPLHSCVSCHAS------NPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTA-
RKGKRHHAHVNVSWCFVCSK-----------------------------------------------------GGSLLCC
ESCPAAFHPDCLNI-EMPDG---SWFCNDCRA---------------GKKLHFQDIIWVKLGNYR-WWPAEVCHPKNVPP
NIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGS-RYQGV-RGIGRVFKNALQEAEARFREIKLQREARETQES
ER---KPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKPTDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQ
YPETKIIKTD-GKGWGLVAKRDIRK------------------GEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTI
DKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAG-TELTFNYNLDCLGNE-KTVCRCGASNCSG
FLGDRPKT------STTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRP
FG-----------KWECPWHHCDV--CGKPSTSFCHFCPNSFCKEHQDGTAFSCTPDGRSYCCEHDLGAASVRSAKTEKP
PPEPGKPKGKRRRRR-----GWRRVTEGK---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Otolemur_garnettii_NSD2
-------------------------------------------------------------------MEFSIKK-NPLSV
QKVVKCIKMKQAPEILGNTNGKTQSCEVNRECSVFLSKA---QLSNSLQEGVMQKFNGRDALPFIPAEKLKDLTSRVFNG
EPGTHDAKLRFEPQ-------EMKGMGTP---------------------------------------------------
------------------------------------------------PSTTPVK---NGSPEIKLKITKTYMNGKPLFE
SSICGDSAA------DMSQSGENGQKSENKARRNRKRSVKYDSLLEQGLVEAALVSKISSPSDK----------------
----------------------------------------KIPLKKDS-------------------CPS---------I
GRDKDCLLKYNIGDLVWSKVSGYPWWPCMVSADPLLHSYTKLK--GQKKSA------RQYHVQFFGDAPERAWIFEKSLV
AFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERK---------------------
---------------------AKFTFVYVGDQLHLNPQVAKEAGIAVEF---SGEMAGASEV------------------
------SEETAENPKFVREEA--IPVKRRRRTKLSGSAENQESDP--GTGRNSPQKMAE---------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------ADPKRGVGSPPGRKKT
TASTPRSRKGDAAS-QFLVFCQKHRDEVVAEHPDASGEEIEELLGS-------------------------QWNMLNEKQ
KARYNTKFAPVTSAPSEEDSG------------------------------NL---------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------NGKKRNHTKRTQNPT
DDIEVEDAPRKRLRTDKH--------------------------------------------------------------
--------------------------------------------------------------SLRK-RDTITDKTTRTSS
Y------KVTEAASSLKSQAATKNLS------------------------------------------------DACKPL
KKRNRASATASSALGFSKSSSPSASLTENEVS-DSPGDEPSESPYESADETQTEVSISSKKSERG-MTAKKEYVCQLCEK
TGS--LLLCEGPCCGAFHLSCLGLSRRPEGRFTCSECTSGIHSCFVCKESK------TDVKRCVVTQCGKFYHETCVRKF
PLTVFESRG-FRCPLHSCVSCHAS------NPANPRPSKGKMMRCVRCPVAYHGGDACLAAGCSVIASNSIVCTAHFTA-
RKGKRHHAHVNVSWCFVCSK-----------------------------------------------------GGSLLCC
ESCPAAFHPDCLNI-EMPDG---SWFCNDCRA---------------GKRLHFQDIIWVKLGNYR-WWPAEVCHPKNVPP
NIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGS-RYQGV-RGIGRVFKNALQEAEARFREIKLQREARETQEN
ER---KPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKPTDENPCGFDSECLNRMLMFECHPQVCPAGEYCQNQCFTKRQ
YPETKIIKTD-GKGWGLVAKRDIRK------------------GEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTI
DKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAG-TAL--------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Homo_Sapien_NSD3
-------------------------------------------------------------MDFSFSFMQGIMGNTIQQP
PQLIDSANIRQE-DAFDNNSDIAEDGGQTPYEATL--QQGFQYP-ATTEDLPPLTNGYPSSISVYETQTKYQSYNQYPNG
SANGFGAVRNFSPTDYYHSEIPNTRPHEILEKPSPPQP------------------------------------------
--------------------------------------------PPPPSVPQTVIPKKTGSPEIKLKITKTIQNGRELFE
SSLCGDLLNEVQASEHT-----KSKHESRKEKRKKSNKHDSSRSEERKSHKIPKLEPEEQNRPNE---------------
--------------------------------------RVDTVSEKPREEPVLKEEAPVQPILSSVPTTE----------
---VSTGVKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKIN-TRGA---------REYHVQFFSNQPERAWVHEKRVR
EYKGHKQYEELLAEATKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERI---------------------
---------------------EQYTFIYIDKQPEEALSQAKKSVASKTEVKKTRRPRSVLNT------------------
------------QPEQTNAGEVASSLSSTEIRRHSQRRHTSAEEEE----------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------PPPVKIA
WKTAAARKSLPASIT---MHKGSLDLQKCNMSPVVKIEQVFALQN----------------------------ATGDGKF
IDQFVYSTKGIGNKTEISVRGQDRLI------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------ISTPNQRNEKPT
QS---VSSPEATSGSTGSV-------------------------------------------------------------
--------------------------------------------------------------EKKQQRRSIRTRSESEKS
TEV-VPKKKIKKEQVETVPQATVKTG---------------------------------------LQKGASEISDSCKPL
KKRSRASTDVEMT-SSAYRDTSDSDSRGLSDLQVGFGKQVDSPSATADADVSDVQSMDSSLSRRGTGMSKKDTVCQICES
SGD-SLIPCEGECCKHFHLECLGLASLPDSKFICMECKTGQHPCFSCKVSGK------DVKRCSVGACGKFYHEACVRKF
PTAIFESKG-FRCPQHCCSACSMEK-------DIHKASKGRMMRCLRCPVAYHSGDACIAAGSMLVSSYILICSNHS---
KRSSNSS-AVNVGFCFVCARGLIVQDHSDPMFSSYAYKSHYLLNESNR-AELMKLPMIP-SSSASKKKCEK--GGRLLCC
ESCPASFHPECLSI-EMPEG---CWNCNDCKA---------------GKKLHYKQIVWVKLGNYR-WWPAEICNPRSVPL
NIQGLKHDLGDFPVFFFGSHDYYWVHQGRVFPYVEGDK-SFAEGQT--SINKTFKKALEEAAKRFQELKAQRESKEALEI
EKNSRKPPPYKHIKANKVIGKVQIQVADLSEIPRCNCKPADENPCGLESECLNRMLQYECHPQVCPAGDRCQNQCFTKRL
YPDAEIIKTE-RRGWGLRTKRSIKK------------------GEFVNEYVGELIDEEECRLRIKRAHENSVTNFYMLTV
TKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDVRVGLFALCDIPAG-MELTFNYNLDCLGNG-RTECHCGADNCSG
FLGVRPKSA-----CASTNEEKAKNAKLKQKRRKIKTE-PKQMHEDYCFQCGDGGELVMCDKKDCPKAYHLLCLNLTQPP
YG-----------KWECPWHQCDE--CSSAAVSFCEFCPHSFCKDHEKGALVPSALEGRLCCSEHDPMAPVS--------
-PEYWSKIKCKWESQDHGEEVKE---------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Mus_musculus_NSD3
-------------------------------------------------------------MDFSFSFMQGIMGNTIQQP
PQLIDSANIRQE-DAFDNHSDIVEDGGPTPFEATL--QQGFQYP-PTTEDLPPLTNGYPPSISLYETQTKYPPYNQYPNG
SANGFGAVRNFSPTDYYHSEIPNTRPHEILEKPSPPQPPPLP--------------------------------------
--------------------------------------PPPPPPPPPPSVPQTVIPKKTGSPEIKLKITKTIQNGRELFE
SSLCGDLLNEVQASEHT-----KSKHESRKEKRKKSNRHESSRSEERRSHKIPKLEPEGQNRPNE---------------
--------------------------------------RVDTAPEKPREEPVLKEAIPVQPILSSVPTTE----------
---TSTGVKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHSKIN-TRGA---------REYHVQFFSNQPERAWVHEKRVR
EYKGHEQYEELLAEAAKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERV---------------------
---------------------EQYTFIYIDKQPEEASSQAKKNVTSKTEVKKPRRPRSVLNS------------------
------------QPEQTNAGEVASSQSSTDLRRQSQRRHTSLEEEE----------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------PPPVKIA
WKTAAARKSLPASIT---MHKGSLDLQKCNMSPVVKIEQVFALQN----------------------------ATGDGKF
IDQFVYSTKGIGNKTEISVRGQDRLI------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------ISSPSQRSEKPA
QS---ASSPEATSGSAGPV-------------------------------------------------------------
--------------------------------------------------------------EKKQQRRSIRTRSESEKS
AEV-VPKKKIKKEQVETAPQASLKTG---------------------------------------LQKGASEISDSCKPL
KKRSRASTDVETA-SCTYRDTSDSDSRGLSDGQVGFGKQVDSPSATADADASDAQSVDSSLSRRGVGTSKKDTVCQVCEK
AGD-CLVACEGECCRHFHVECLGLTAVPEGHFTCEECETGQHPCFSCKVSGK------DVKRCSVSVCGKFYHEACVRKF
PTAIFESKG-FRCPQHCCSSCSMEK-------DIHKASKGRMMRCLRCPVAYHVGDACVAAGSVSVSSHILICSNHS---
KR-SSQSAAINVGFCFVCARGLIVQDHSDPMFSSYAYKSHYLLSESNR-AELMKLPMIP-SSSASKKRCEK--GGRLLCC
ESCPASFHPECLSI-DMPEG---CWNCNDCKA---------------GKKLHYKQIVWVKLGNYR-WWPAEICSPRSVPL
NIQGLKHDLGDFPVFFFGSHDYYWVHQGRVFPYVEGDK-HFAEGQT--SINKTFKKALEEAAKRFQELKAQRESKEALEM
ERTSRKPPPYKHIKANKVIGKVQVQVADLSEIPRCNCKPGDENPCGLESQCLNRMSQYECHPQVCPAGDRCQNQCFTKRL
YPDAEVIKTE-RRGWGLRTKRSIKK------------------GEFVNEYVGELIDEEECRLRIKRAHENSVTNFYMLTV
TKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDVRVGLFALCDIPAG-MELTFNYNLDCLGNG-RTVCHCGADNCSG
FLGVRPKSA-----CTSAVDEKTKNAKLK-KRRKVKAE-AKPIHEDYCFQCGDGGELVMCDKKDCPKAYHLLCLNLTQPP
HG-----------KWECPWHRCDE--CGSVAVSFCEFCPHSFCKAHGKGALVPSALEGRLCCSSHDPASPVS--------
-PEYWSKIRCKWESQDSGEEVKE---------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Callithrix_jacchus_NSD3
-------------------------------------------------------------MDFSFSFMQGIMGNTIQQP
PQLIDSANIRQE-DAFDNNSDIAEDGGQTPYEATL--QQGFQYP-STTEDLPPLTNGYPSSISMYEPQTKYQSYNQYPNG
SANGFGAVRNFSPTDYYHSEIPNTRPHEILEKPSPPQP------------------------------------------
--------------------------------------------PPPPSVPQTVIPKKTGSPEIKLKITKTIQNGRELFE
SSLCGDLLNEVQASEHT-----KSKHESRKEKRKKSNKHDSSRSEERKSHKIPKLEPEEQNRPNE---------------
--------------------------------------RVDSVAEKPREDPVLKEEAPVQPILSSVPTTE----------
---VSTGVKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKIN-TRGA---------REYHVQFFSNQPERAWVHEKRVR
EYKGHKQYEELLAEATKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERI---------------------
---------------------EQYTFIYIDKQPEEALSQAKKNVASKTEVKKTRRPRSVLNT------------------
------------QPEQTNAGEVASSLSSTEIRRHSQRRHTSVEEEE----------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------PPPVKIA
WKTAAARKSLPASIT---MHKGSLDLQKCNMSPVVKIEQVFALQN----------------------------ATGDGKF
IDQFVYSTKGIGNKTEISVRGQDRLI------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------ISTPNQRNEKPT
QS---VSSPEATSGSTGSV-------------------------------------------------------------
--------------------------------------------------------------EKKQQRRSIRTRSESEKS
TEV-VPKKKIKKEQVETVPQATVKTG---------------------------------------LQKGASEISDSCKPL
KKRSRASTDVEMT-SSAYRDTSDSDSRGLSDLQVGFGKQVDSPSATADADISDVQSMDSSLSRRGTGMSKKDTVCQICES
SGD-SLIACEGECCRHFHLECLGLTSLPDSRFICMECKTGQHPCFSCKVSGK------DVKRCSVGACGKFYHEACVRKF
PTAIFESKG-FRCPQHCCSTCSMEK-------DIHKASKGRMMRCLRCPVAYHTGDACIAAGSMLVSSYILICSNHS---
KRSSNSSSAVNVGFCFVCARGLIVQDHSDPMFSSYAYKSHYLLNESNR-AELMKLPMIP-SSSASKKKCEK--GGRLLCC
ESCPASFHPECLSI-EMPEG---CWNCNDCKA---------------GKKLHYKQIVWVKLGNYR-WWPAEICNPRSVPL
NIQGLKHDLGDFPVFFFGSHDYYWVHQGRVFPYVEGDK-SFAEGQT--SINKTFKKALEEAAKRFQELKAQRESKEALEI
EKNSRKPPPYKHIKANKVIGKVQIQVADLSEIPRCNCKPADENPCGLESECLNRMLQYECHPQVCPAGDRCQNQCFTKRL
YPDAEIIKTE-RRGWGLRTKRSIKK------------------GEFVNEYVGELIDEEECRLRIKRAHENSVTNFYMLTV
TKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDVRVGLFALCDIPAG-MELTFNYNLDCLGNG-RTECHCGADNCSG
FLGVRPKSA-----CASTTEEKAKNAKLKQKRRKIKTE-PKQMHEDYCFQCGDGGELVMCDKKDCPKAYHLLCLNLTQPP
YG-----------KWECPWHQCDE--CSSAAVSFCEFCPHSFCKDHEKGALVPSALEGRLCCSEHDPMSPVS--------
-PEYWSKIKCKWESQDHGEEVKE---------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Rattus_norvegicus_NSD3
-------------------------------------------------------------MDFSFSFMQGIMGNTIQQP
PQLIDSANIRQE-DAFDNNSDIVEDGGPTPFEATL--QQGFQCP-PATEDLPPLTNGYPPSISLYETQTKYPPYSQYPNG
SANGFGAVRNFSPTDYYHSEIPNTRPHEILEKPSPPQPP-----------------------------------------
--------------------------------------PPPLLPPPPPPVPQTVIPKKTGSPEIKLKITKTIQNGRELFE
SSLCGDLLNEVQASEHL-----KSKHESRKEKRKKSSRHESSRSEERKSHKVPKLEPEGQNRPNE---------------
--------------------------------------RVDPAPEKPREEPVLKEAVPVQPILSSVPTTE----------
---TSTGVKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKIN-TRGA---------REYHVQFFSNQPERAWVHEKRVR
EYKGHEQYEELLAEAAKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALQMTREERV---------------------
---------------------EQYTFIYIDKQPEESPSQAKKSVTSKAEVKKPRRPRSVGNS------------------
------------QPEQTSAGEVASPQSSTDPRRQSQRRHTSVEEDG----------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------PPPVKIA
WRTAAARKSLPASIT---MHKGSLDLHKCNMSPVVKIEQVFALQN----------------------------ATGDGKF
IDQFVYSTKGIGNKTEISVRGQDRLI------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------ISSPSQRNEKST
PS---ASPPEATSGSAGPV-------------------------------------------------------------
--------------------------------------------------------------EKKQQRRSIRTRSESEKS
TEV-VSKKKIKKEQVETSPQASLKTG---------------------------------------LQKGASEISDSCKPL
KKRSRASTDVETA-SCTYRDTSDSDSRGPSDGQVGFGKQVDSPSAAADADASDAQSVDSSLSRRGVGLSKKDTVCQVCEN
TGD-SLVACEGECCRHFHPECLGLAAVPEGRFTCEECETGQHPCFSCKVSGK------DVKRCSVSVCGKFYHEACVRKF
PTAIFESKG-FRCPQHCCSSCSMEK-------DIHKASKGRMMKCLRCPIAYHFGDACVAAGSVSVSSHILICSNHS---
KR-SSHSAAINVGFCFVCARGLIVQDHSDPMFSSYAYKSHYLLSESNR-AELMKLPMIP-SSSASKKRCEK--GGRLLCC
ESCPASFHPECLSI-DMPEG---CWNCNDCKA---------------GKKLHYKQIVWVKLGNYR-WWPAETCSPRSVPL
NIQGLKHGVGDFPVLFFGSHDYYWVHQGRVFPYVEGDT-NFAEGQT--SINKTFKKALEEAAKRFQELKAQRESKEALEI
EKTSRKPPPYKHIKANKVIGKVQIQVADLSEIPRCNCKPGDENPCGLESECLNRMSQYECHPQVCPAGDRCQNQCFTKRL
YPDAEIIKTE-RRGWGLRTKRSIKK------------------GEFVNEYVGELIDEEECRLRIKRAHENSVTNFYMLTV
TKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDVRVGLFALCDIPAG-MELTFNYNLDCLGNG-RTVCHCGADNCSG
FLGVRPKSA-----CTSAADEKTKNAKLK-KRRRGKAE-AKQIHEDYCFQCGDGGELVMCDKKDCPKAYHLLCLNLTQPP
YG-----------KWECPWHQCDE--CGSAAISFCEFCPHSFCKAHEKGALVPSALEGRLCCSNHDPASPVS--------
-PEYWSKMRCKWESQDGGEEVKE---------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Equus_caballus_NSD3
-------------------------------------------------------------MDFSFSFMQGIMGNTIQQP
PQLIDSANIRQE-DAFDNNSDIVEDGGQTPYEATL--QQGFQYP-PTTEDLPPLTNGYPPSISMYETQTKYQSYNQYPNG
SANGFGAVRNFSPADYYHSDIPNTRPHEILEKPSPPQP------------------------------------------
--------------------------------------------PPPPSVPQTVIPKKTGSPEIKLKITKTIQNGRELFE
SSLCGDLLNEVQASEHT-----KSKHESRKEKRKKSNKHDSSRSEERKSHKIPKLEPEEQNRPNE---------------
--------------------------------------RVDTVSEKPREDLVLKEETPVQPILSSVPTTE----------
---VSTGVKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKIN-TRGA---------REYHVQFFSNQPERAWVHEKRVR
EYKGHKQYEELLAEATKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERI---------------------
---------------------EQYTFIYIDKQPEEALSQAKKNVASKAEVKKTRRPRSVLNT------------------
------------QPEQTNAGEVASSLSSTEIRRHSQRRHMSVEEEE----------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------PPPVKIA
WKTAAARKSLPASIT---MHKGSLDLQKCNMSPVVKIEQVFALQN----------------------------ATGDGKF
IDQFVYSTKGIGNKTEISVRGQDRLI------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------ISTPNQRNEKAT
QN---ISSPETTSGSTGSA-------------------------------------------------------------
--------------------------------------------------------------EKKQQRRSIRTRSESEKS
TEV-VPKKKIKKEQVETVPQATVKTG---------------------------------------LQKGASEISDSCKPL
KKRSRASTDVEMT-SSAYRDTSDSDSRGLSDLQVGFGKQVDSPSATAEADVSDVQSVDSSLSRRGIGMSKKDAVCQVCES
SGD-SLIPCEGECCKHFHLECLGLASLPDGKFVCMECKTGQHPCFSCKMSGT------DVKRCSVGACGKFYHEACVRKF
PTAIFESKG-FRCPQHCCSACSMEK-------DVHKASKGRMMRCLRCPVAYHTGDACIAAGSMSVSSCIFICSNHS---
KRSSNSSSAVNVGFCFVCARGLIVQDHSDPMFSSYAYKSHYLLNESNR-AELMKLPMIP-SSSASKKKCEK--GGRLLCC
ESCPASFHPECLSI-EMPEG---CWNCNDCKA---------------GKKLHYKQIVWVKLGNYR-WWPAEICNPRSVPL
NIQGLKHDLGDFPVFFFGSHDYYWVHQGRVFPYVEGDK-SFAEGQT--SINKTFKKALEEAAKRFQELKAQRESKEALEI
EKSSRKPPPYKHIKANKVIGKVQIQVADLSEIPRCNCKPADENPCGLESECLNRMLQYECHPQVCPAGDRCQNQCFTKRL
YPDAEIIKTE-RRGWGLRTKRSIKK------------------GEFVNEYVGELIDEEECRLRIKRAHENSVTNFYMLTV
TKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDVRVGLFALCDIPAG-MELTFNYNLDCLGNG-RTECHCGADNCSG
FLGVRPKSA-----CASTTEEKAKNAKLKQKRRKIKTE-PKQMHEDYCFQCGDGGELVMCDKKDCPKAYHLLCLNLTQPP
YG-----------KWECPWHQCNE--CSSAAVSFCEFCPRSFCKDHEKGLLVPSALEGRLCCSEHDPVSPVS--------
-SEYWSKIKCKLESQDPGEEVKE---------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Monodelphis_domestica_NSD3
-------------------------------------------------------------MDFSFSFMQGIMGNTIQQP
PQLIDSANIRQE-DAFDNSSDIVEDG-QTPYETSL--QQGFQYP-PTTEELPPITNGYPPSISMYEPQAKYQTYSQYPNG
SANGFGAVRNFSPTDYYHTEISNTRPHEVLEKPSPQQP------------------------------------------
--------------------------------------------PPPPSVPQTVIPKKTGSPEIKLKITKTIQNGRELFE
SSLCGDLLNEVQASEYA-----KSKHEGRKEKRKKSNKHDSSKSEERKSHKIPKLEPEEQNRPNE---------------
--------------------------------------RVNVLSEKPREDSMVLEETPVQQYLPSLP-AE----------
---VSTGVKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKIN-TRGA---------REYHVQFFSNQPERAWVHEKRVR
EYKGHKQYEQLLAEATKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERI---------------------
---------------------EQYTFIYVDKQPEEVLSQAKKSAASKTEVKKNRRPKAVLNT------------------
------------QPEQSNAGEAASSLPSTEIRRHSQRRHTSVEEEE----------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------PPPVKIA
WKTAAARKSLPASIT---MHKGSLDLQKCNMSPVVKIEQVFALQN----------------------------AAGDGKF
IDQFVYSTKGVGNKTEISVRGQDKLI------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------ISTTNQRNEKAT
QN---VSSPETTSGSTGSV-------------------------------------------------------------
--------------------------------------------------------------EKKQQRRSIRTRSESEKS
TEV-VPKKKIKKEQVETVPQTTVKTG---------------------------------------LQKGASEISDSCKPL
KKRSRASTDVEMT-SSAYRDTSDSDSRGLNDLQVSFGKQLDSPSAAADADASDVQSVDSSLSRRGTGTSKKDTVCQICES
YSD-SLVVCEGECCKHFHPDCLGLSSLPDGRFLCTECKTGHRTCFSCKIPGK------DVKRCSVPACGKFYHEACVRKF
ATAVFESRG-FRCPQHCCSTCSMEK-------DIHKASKGRMMRCLRCPIAYHSGDGCIAAGSRCVSSYLLICSNHS---
KRSNHSSSTINVGFCFVCARGLIVQDHSDPMFSSYAYKSHYLLNESNR-AELK-LPMIP-SSSASKKKCEK--GGKLLCC
ESCPASFHPECLNI-EMPEG---CWNCNDCKA---------------GKKLHYKQIVWVKLGNYR-WWPAEICNPRSVPL
NIQGLKHDLGDFPVFFFGSHDYYWVHQGRVFPYVEGDK-SFAEGQT--SINKTFKKALEEAAKRFHELKAQRENKEALEL
ERNSRKPPPYKHIKANKVIGKVQIQVADLSEIPRCNCKPADENPCGLESECLNRMLQYECHPQVCPAGDRCQNQCFTKRL
YPDAEVIKTE-RRGWGLRTKRSIKK------------------GEFVNEYVGELIDEEECRLRIKRAHENSITNFYMLTV
TKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDIRVGLFALCDIPAG-VELTFNYNLDCLGNG-RTECHCGADNCSG
FLGVRPKTA-----FASANEEKAKNAKLKQKKRKIKTE-QKQMHEDYCFQCGDGGELVMCDKKDCPKAYHLLCLNLTQPP
YG-----------KWECPWHQCDT--CSNSAVSFCEFCPRSFCKDHEKGALVPSTLEGRLCCSKHNPKSPVA--------
-PEYWNKIRCKLEPQDPGDEVKE---------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Gallus_gallus_NSD3
-------------------------------------------------------------MDFSFSFMQGIMGNTIQQP
PQLIDSANIRQE-DAFDASSDIAEDGGQTPYEAAL--QQGFQYPTPTAEDLPPIANGYPATINMYEPQAKFQTYSQYPNG
SANGFGTVRNFSPPEYYHMENSNARPHEVLEKPSPPQP------------------------------------------
-------------------------------------------PPPPPPVSQTVIPKKTGSPEIKLKITKTIQNGRELFE
SSLCGDLLNEVQASEYA-----KAKHEGRKEKRKKSSKHDSSRSEERKSHKIPKLEPEEQNRPNE---------------
--------------------------------------RLSMLSERPRED-ALLEEAPVQQFLPSLP-TQ----------
---VSHDIKFQVGDLVWSKVGTYPWWPCMVSCDPQLDVHTKIN-TRGA---------REYHVQFFSNQPERAWVHEKRVR
EYKGHKQYEQLLAEAAKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERI---------------------
---------------------EQYTFIYIDKEPEEVLSKAKKTTASKSETKKNRRPKPALNT------------------
------------QTEHANVVT--GSPSSAELRRQSQRRQSSAEEEE----------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------PPPVKIA
WKTAAARKSLPASIT---MHN--LDLQKCNMSPVVKIEQVFALQN----------------------------AAGDGKL
IDQFVYSTKGVGNKAEISVKGQEKLN------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------SSS-SQRNEKAT
CNVQNASSPETTSGSAGSV-------------------------------------------------------------
--------------------------------------------------------------EKKQQRRSIRTRSESEKS
TEV-VPKKKIKKEQVEMVPLTAVKTG---------------------------------------LQKGASEISDSCKPL
KKRSRASTDVELT-SSAYRDASDSDSRGLNDLQGSFGKRSDSPSAAVDADASDVQSVDSSLSRRGTGTNKKDTVCQICES
SGE-SLVSCEGECCSTFHMECLGLKAMPEEKFFCTECKNGEHTCFSCKLPGK------DVKRCSVSACGKFYHEACVRKF
ATALFESRG-FRCPQHCCSACSVDK-------DIHKASKGRMVRCFRCPIAYHSGDGCIAAGSLFVSSHILICSNHS---
KR-NHSSSAVNVGFCFVCARGLVVQDHSDPLFSSYAYKSHYLLNESNR-AELMKLPMIPPPSSASKKKCEK--GGKLLCC
ESCPASFHPECLNI-DMPEG---CWNCNDCKA---------------GKKLRYKQIVWVKLGNYR-WWPAEICNPRSVPL
NIQGLKHDIGDFPVFFFGSHDYYWVHQGRVFPYVEGDK-SFAEGQT--SINKTFKKALEEAAKRFQELKAQRESKEALEI
ERNSRKPPPYKHIKSNKVIGKVQIQVADLSEIPRCNCKPSDENPCGLESECLNRMLQYECHPQVCPAGERCQNQCFTKRL
YPDAEIIKTD-RRGWGLRTKRNIKK------------------GEFVNEYVGELIDEEECRLRIKRAHENSVTNFYMLTV
TKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDIRVGLFALCDIPAG-MELTFNYNLDCLGNG-RTECHCGAENCSG
FLGVRPKTA-----FATANEEKVKNAKLKQKKRKIKTE-QKQMHEDNCFQCGDGGELVMCDKKDCPKAYHLLCLNLTQPP
FG-----------KWECPWHQCDI--CSSPAVSFCEFCPHSFCKDHEKGALLASALDGRLCCSTHDPKSPVA--------
-PEYWNKIKCKLEPQNPVEEAKE---------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Anolis_carolinensis_NSD3
-------------------------------------------------------------MDFSFSFMQGIMGNTIQQP
PQLIDSANNRQE-DAFDASSDITEDGRQTPYEAALSLQQGFQYPTPTTEDLPPLINGFPP-ISMYEPQAKYQSYSQYPNG
SANGFGSVRNFSPPEYYQMENSNLRPHEILEKQSPPQP------------------------------------------
-------------------------------------------PPP--SVSQTVIPKKTGSPEIKLKITKTIQNGRELFE
SSLCGDLLNEVQASEYA-----KPKHEGRKEKRKKSNKHDASHSEERKSHKIPKLEPEEQNRPNE---------------
--------------------------------------RISNQSERPREEPIVLDETPVQEASPSPP-TP----------
---VVSDVTFEVGDLVWSKVGTYPWWPCMVSRDPQLEVHTKIN-TRGA---------REYHVQFFSNQPERAWVHEKRVR
EYKGRKQYDQLVAEATKQAN-HSEKQKIRKPRPQRERAQWDIGIAHAEKALKMSREERI---------------------
---------------------EQYTFIYVDKEPEEALTKTRRTVVPKMEARKNRRSKPSPSP------------------
------------QPEPASEASPASSPSNTEVRRHSQRRQSSVEEE-----------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------PPPVKIA
WKTAAARKSLPASIT---MHQGTLDLQKCNMSPVVKIEQVFALQN----------------------------AAGNGKF
IDQFVYSTKGLGSKPEIIIKGHDKLT------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------SVS-SQRNERAS
S--QRSPSPETSSGLASSV-------------------------------------------------------------
--------------------------------------------------------------EKKQQRRSIRTRSESEKS
TEV-VPKKKIKKEQVETAPQTALKTG---------------------------------------LQKGASEISDSCKPL
KKRSRASTDVELT-SSAYRDTSDSDSRGLNDLQGSFGKQSDSPSAAADADASDVQSVDSSLSRRGSGTSKKDSICQICES
SGE-SLLSCEGECYRVFHTECLGLSSQPEGKFICIECKNGQHTCFSCKLPGK------DVKRCSVNACGKFYHEACVRKF
ATTVFESRG-FRCPQHCCTSCSVDK-------DIHKASKGRMVRCLRCPIAYHSGDGCIAAGSLFVSSHILICSNHS---
KRSNHSSSAVNVGFCFVCARGLIVQDHSDPLFSSYANKSHYLLNESNR-AELMKLPMIPPSSSASKKKCEK--GGKLLCC
ESCPASFHPECLHI-EMPNG---SWNCNDCKA---------------GKKLRYKQIVWVKLGNYR-WWPAEICNPRSVPL
NIQGLKHDIGDFPVFFFGSHDYYWVHQGRVFPYVEGDK-SFAEGQT--NINKTFKKALEEAAKRFQELKAQRESKEALEI
ERNSRKPPPYKHIKSNKVVGKVQIQVADLSEIPRCNCKPSDENPCGLESECLNRMLQYECHPQVCPAGEGCQNQCFTKRL
YPEAEIIKTD-RRGWGLRTKRNIKK------------------GEFVNEYVGELIDEEECRLRIKRAHENSVTNFYMLTV
TKDRIIDAGPKGNYSRFMNHSCHPNCETQKWTVNGDVRVGLFAVCDIPAG-MELTFNYNLDCLGNG-RTECHCGADNCSG
FLGVRPKTA-----CATANEEKAKNAKLKQKKRKIKTE-QKQMHEDNCFQCGDGGELVMCDKKDCPKAYHLLCLNLTQPP
FG-----------KWECPWHQCEI--CGNPATSFCEFCPHAYCKEHEKGALVASALEGRPCCSEHNPKAPVA--------
-PEYWCKIKRRLEQQNPEEEAKE---------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Danio_rerio_NSD3
-------------------------------------------------------------MDFSFSFMQGIMGNTIQQP
PQLIDSANIRQE-DVYEAISDPGDDGGQQNFDSPL--ESGFSYP---AEDVPVITNGYPTGVGTYEQQAKFALYSQFPNG
SANGYGAIRNYGDHSLLLGEGTVLRPPVVQEKPQTHISPPSHSHHHQQPHHPHHHHHQQQQQHHP--------HNPPLLP
HHHHHHPPPASHLMPQVLPPPPPLLLPSSPPLLSPQESTISNPIGQPVNTIITTTPKKTSSPEIKLKIIKTYQNGRELFE
SSLCGDLLQEFQAGEDS-----RRQHEQKKEKRKKRGSRHGAGHEESQ---QPSKVEEERSVVVH---------------
--------------------------------------NPVQTTESQVAFREEQQPQSSLKSPKAELKEQKVEK-HCPSV
ITSTGTSQEYEIGDLVWAKVGTYPWWPCMVSSDPQSNVHTRIN-TRGC---------KEYHVQFFGSVPERAWIHEKRTV
VYKSENQFDELQAETLRKSTNPTEKQKLLKPQSQKERAQWEVGVGHAEAALQMTREERN---------------------
---------------------ENYTFIYIDKEPGADAET-AAAPAPAPD-SAPTAPTDTVTSPKATAKNRPERKQRRSRG
SAGAKEEPIPRRQQPRRQCSMNSVGETSSPNQGEDAMEQEQPCSPPKP--------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------APRPKEPSPPPVRTP
WRTAAARKLLPLSIT---MKKLNVEIIKCDWQLPKQKVELPKKTESEE-----------------RPSSRVKSPEGSSNK
AEAETCSSEEERAASPSGWSDQEHTSAEQSTG------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------IHWISASTERKQ
RC----TDVVLRCKSDQGN-------------------------------------------------------------
------------------------------------------------------VLCVCAKTERKQQRRSVRSRSESEKS
VEP-VPKKKVKKEQAETAPQMDFKTG---------------------------------------SQKGASEISDSCKPL
KKRSRASTDVEMA-SSLYRDTSDSDSRGLNDPQTGFGKRSDSPAT-VDADGSDAQSVDSSLSRQGGSSSKKDTVCHVCET
FGD-SLVSCEGDCNRLFHPECMGSNSGKESETVCQECKTGSHPCFSCKVTEG------DMKRCSVNGCGRYYHETCVRKY
TGSASDTKG-LRCPQHSCATCCLDR-------DLQKAGKGRMMRCIRCPVAYHTGDGCVAAGSVLITPHIIICSNHSSS-
RKNGHFSSPVNVGWCFICAR-----------------------------------------------------GGRLLCC
EACPASFHPECLKI-EMPEG---TWLCGECKS---------------GKKPHYKQIVWVKLGNYR-WWPAEICNPRLVPS
NIQSLKHDIGDFPVFFFGSHDYYWINQGRVFPYVESDK-NFAEGQV--GINKTFKKALEEAAKRFQELKAQRETKEALEQ
ERNSRRPPPYKLIKSNKPFGKVQLHVADLSEIPRCNCKPTDERPCSQDSQCLNRMLQYECHPQVCPAGDRCHNQCFSKRL
YPDTEVIKTT-GRGWGLKTKQDLKK------------------GDFVMEYVGELIDSEECKQRIRTANENHVTNFYMLTL
TKDRVIDAGPKGNLSRFMNHSCSPNCETQKWTVNGDVRIGLFTLCDISAD-TELTFNYNLDCLGNG-RTSCHCGSENCSG
FLGVKPKSA-----VVMEREEKVRNAKLKPKKRKLKTE-SKQTHELYCYCCGEGGELVMCDKKDCPKAYHLLCLNLSKPP
YG-----------RWECPWHQCSV--CQRTATSFCHFCPASFCREHERGQLAVSALDKQPCCSNHDPKRPLG--------
PQANRSQVTVKKEPLDGNANEEEEEEEEETGDGE----------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Takifugu_rubripes_NSD3
-------------------------------------------------------------MDFSFSFMQGIMGNTIQQP
PQLIDSANIRQE-GTCDTGSDPGEDGGP-SYDAAL--DSEFSYPPSASEDMSQVSNGYPPGLGLYEPQAKFSMYSQFPNG
SANGYGAIRSYGEHGLLPGEGTVLRGPGLQERPLSPVSPPLSTHHPHLHHHHHHHAHHYHSNQP---HIQTHPHTQSPPP
PPSQHHLSQTPHIMTHTLPHPPPLHLPSSSPPPSLVDSTPSSQPSHAPSNTSGGVLKKTSSPEIKLKIIKTYQNGKELFE
SALCGDLLEELQESQKKEASQTQRRHERKKEKRKKSARLQLQVQEQS----LNQSQTQAGTLTLP---------------
--------------------------------------DDTNMHPQLVEMP--QTEKPQKTTVKTVPKTPKVPKVHHQSV
IQETGFCKEFVIGDLVWSKVGTYPWWPCMVSSDPQMKVHTRIN-TRGH---------REYHVQFFGSVAERAWIHEKRIV
IYQGKQQFEDLQAETLRKATNPVEKQKLMKPIPQRERSQWEVGVGHAEDAFVMTRQERI---------------------
---------------------DNYTFIYVDPDPNEAPP--SKKPNIRAE-KQNRRSSGSVRKEEGGV---------KSPD
REQPPRRQLPRRQCSVSNTDDSTNSQASNDDHRESQHSATSPKQSVGC--------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------DVQDQQDSPPPVR-A
WKTAAARKLLPLSIT---MKRLNVEITKCDWPLLQKKAALSPKN---------------------DSDEKEERVEREARQ
PDLGYCSPEECRAKPEPSLEEDEDGDEGEEESD-----------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------DRRGSPASQKSEEGDMQQ
MY----SPGSHHSSPQGSQ-------------------------------------------------------------
--------------------------------------------------------------ERKLQRRSVRSRSESERG
SDP-VPKKKTKKEQAEIAPETTLRTG---------------------------------------SQKGASEISDACKPL
KKRSRASTDVEMA-SSQYRDTSDSDSRGLSDPQGLFGKNLDSPAA-ADG--SDTQSVDSGLSRQDSNTDKRDTVCQICEA
YGE-SLVVCEGDCNRQFHLECLGLTAQPEGRFICLECRNGDHPCFSCKTAGQ------EVTRCSVSGCGCYYHEDCVRKL
LGTTSSPGGGFCCPQHICSTCCLER-------DLQRASKGRLMRCIRCPVAYHTGDSCVAAGSVVLTHHIMICSSHGST-
KRNGLLTSPINVSWCFLCARGLLVQDLTDTILSSYAYKSHYLLTESNR-AEL-KLPMIPSPSSATKKNVGK--GGKLLCC
DSCPASFHPECLEM-EMPEG---PWSCSDCRT---------------GKKPHYKQIVWVKLGNYR-WWPAEICNPRLVPS
NIQSLRHDIGDFPVFFFGSHDYYWINQGRVFPYVESDK-NFVTGQI--NINKTFKKALEEAARRFQELKAQRESREALEQ
ERNSRKPPPYKFIKSNKPVGKVQMHVADLSEIQRCNCRPTDEHPCGLHSQCLNRMLQYECHPQVCPAGDNCENQGFTKRL
YAETEVVKTA-DRGWGLKANQPLKK------------------GEFVTEYVGEVIDAEECQQRIKRAHENHMTNFYMLTL
TKDRVIDAAQKGNLSRFINHSCSPNCETQKWTVNGDVHIGLFALCDIDAG-TELTFNYNLHCVGNR-RTTCNCGSDNCSG
FLGVQPTSA-----VVLEKEEKARNAKLKPKKRKLRLE-GKHTHEYYCFCCGEGGELVMCDRKDCPKAYHLLCLNLTKPP
YG-----------RWECPWHDCTI--CSAPASSSCDFCPRSFCQEHEEGALTSSSLEGRLCCSSHDPASPLGSNSCSTQP
HCSTSSPLRVKEEPETETDPMAAE--------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Tetraodon_nigroviridis_NSD3
-------------------------------------------------------------MDFSFSFMQGIMGNTIQQP
PQLIDSANIRQE-GTCDTGSDPGEDGGP-SYDAAL--DSEFSYPPSASEDMSQVSNGYPPGLGLYEPQAKFSMYSQFPNG
SANGYGAIRSYGEHGLLPGEGTVLRGPGLQERPLSPVSPP----------------------------------------
----------------------------------------------VPSNTTGGVLKKTSSPEIKLKIIKTYQNGKELFE
SALCGDLLQELQESQKKEAAQMQRRHERKKEKRKKSARLQLQVQEQSQEQSLNQSQVQAGTLTPT---------------
--------------------------------------DDPLMHPQLVETP--QTEKPQKTTVKTVPKTP----------
-------KEFVIGDLVWSKVGTYPWWPCMVSSDPQMKVHTRIN-TRGH---------REYHVQFFGSVAERAWIHEKRIV
IYQGKQQFEELQAETLRKATNPVEKQKLMKPIPQRERSQWEVGVGHAEDAFVMTRQERI---------------------
---------------------DNYTFIYVDPDPNETPP--SKKPNIKAE-KQNRRPSGSVRK------------------
------------QCSVSNTDDSTNSQASNDDQREDQHSGTSPKQSTGC--------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------EVREQPDSPPPVR-A
WKTAAARKLLPLSVT---MKRLNVEITKCDWPLLQKKAALSPKN---------------------DPDEN-----RTAGR
-------------SLNPALKKMRMGMKGRKR-------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------VMTGEGHLPQ
TY----SPGSPHSSPQGWQS------------------------------------------------------------
------------------------------------------------------SGLQGHVLERKLQRRSVRSRSESERG
SDP-VPKKKTKKEQAEMAPETTMRTG---------------------------------------SQKGASEISDACKPL
KKRSRASTDVEMA-SSQYRDTSDSDSRGLSDPQGLFGKNLDSPAA-ADG--SDTQSVDSGLSRQDSNTDKRDTVCQICEA
YGE-GLVVCEGDCSRQFHLECLGLTALPEGRFTCLECLNGKHPCFSCKTAGR------EVTRCSVSGCGCFYHEDCVRKL
LGTTSSPGGGFCCPQHICSTCCLER-------DLQRASKGRLMRCIRCPVAYHTGDSCVAAGSVILTHHIMICSSHE---
ERPPHLPR-VNVSWCFLCARGLLVQDLTDTILSSYAYKSHYLLTESNR-AEL-KLPMIPSPSSATKKNVGKDAGGKLLCC
DSCPASFHPECLEM-EMPEG---PWSCSDCRA---------------GKKPHYKQIVWVKLGNYR-WWPAEICNPRLVPS
NIQSLRHDIGDFPVFFFGSHDYYWINQGRVFPYVENDK-NFVTGQI--NINKTFKKALEEAARRFQELKAQRESREALEQ
ERNSRKPPPYKFIKSNKPVGKVQMHIADLSEVQRCNCRPTDEHPCGLQSQCLNRMLQYECHPQVCPAGDNCENQCFTKRL
YAETEVVKTA-DRGWGLKANQPIKK------------------GEFVIEYVGEVIDAEECQQRIKRAHENHMTNFYMLTL
TKDRVIDAGQKGNLSRFINHSCSPNCETQKWTVNGDVHIGLFALCDIETD-TELTFNYNLHCVGNR-RATCNCGSDNCSG
FLGVQPTSA-----VVLEKEEKAKNAKLKPKKRKLRLE-GKHTHEYYCFCCGEGGELVMCDRKDCPKAYHLLCLNLTKPP
YG-----------RWECPWHDCTL--CSTPASSFCDFCPRSFCRDHEEGALTPSSLEGRLCCSSHDPSSPL---------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Gasterosteus_aculeatus_NSD3
-------------------------------------------------------------MDFSFSFMQGIMGNTIQQP
PQLIDSANIRQE-GTCD--SDPGEDGGP-SYDAAL--DAEFSYPPSASEDMSHVSNGYPPGLGMYEPQAKFSMYSQFPNG
SANGYGAIRSYGDHVLMPGEGTVLRGPGLQERPLSPV-------------------------------------------
------------------------------PPPSLVDNTPSSQPPLGLSNTPDGPLKKTSSPEIKLKIIKTYQNGKELFE
SALCG---DLLQELQKDEATPTQRRHERKKEKRKKSAQLQLQEQDLD---QSQEQQAQEGTTEQT---------------
--------------------------------------EDPNAQPRETETPPAPTEKPPKTTIKVEPKTP----------
-KETGFCKEFVIGDLVWSKVGTYPWWPCMVSSDPQMKVHTRIN-TRGH---------REYHVQFFGSVAERAWIHEKRIV
LYQGKQQYEDLQAETLRRATNPVEKHKLLKPIPQRERSQWEVGVGHAEDAFAMSRQERI---------------------
---------------------DNYTFIYVDPDPIEGPS--SRKPTIRAE-KRNRRSSGSVGKKED---------------
-------------ISNADDAANSKASHEDKDQKGD-----SPKPDAGG--------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------DAR--QGSPPPVR-A
WKTAAARKLLPLSIT---MKRLNVEITKCDWPLLQKKAALSPK--------------------------KEQLVAREARQ
PDLGYCSPEDSRAKPEPSQ-------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------SPASRRSEEGGMQQ
TS----SPGSHHSSPHGSQ-------------------------------------------------------------
--------------------------------------------------------------ERKLQRRSVRSRSESERG
NDP-VPKKKTKKEQAETAPETTLKTG---------------------------------------SQKGASEISDACKPL
KKRSRASTDVEMA-SSQYRDTSDSDSRGLNDPQGLFGKSLDSPAA-ADADASDTQSVDSGLSRQDGSAGKRDTVCQVCEV
YGE-GLLVCEGDCGRQFHLDCLSLTAPPEGRFTCLECMNGNHTCFSCKTAGR------EVTRCSVSGCSCYYHEDCVRKL
PGTSGGSDGGFCCPQHSCSTCCLER-------DLQRASKGRLMRCIRCPVAYHTGDSCVAAGSVALTHHIMICSNHSGA-
KRNGLLTSPINVGWCFLCARGLLVQDLTDTILSSYAYKSHYLLTESNR-AEL-KLPMIPSPSSATKKNVGKDAGGKLLCC
DTCPASFHPECLEM-ETPAG---PWSCSDCRA---------------GKKPHYKQIVWVKLGNYR-WWPAEICNPRLVPS
NIQSLRHDVGDFPVFFFGSHDYYWINQGRVFPYVENDK-NFVTGQI--NINKTFKKALEEAARRFQELKAQRESREALEQ
ERNSRKPPPYKIIKSNKPVGKVQVHVADLSEIQRCNCRPTDEHPCSLNSQCLNRMLQYECHPQVCPAGDSCENQCFSKRL
YAETEVIKTD-GRGWGLQTNQALRK------------------GDFVTEYVGEVIDAEECQQRIKRAHENHVADFYMLTL
TKDRVIDAGPKGNSSRFMNHSCRPNCETQKWTVNGDVRIGLFTLCDVEAG-TELTFNYNLHCVGNR-RSSCHCGSDNCSG
FLGVQPTSA-----VVMEKEEKARNAKLKPKKRKLRPE-GKQTHEYCCFCCGEGGELVMCDRKDCPKAYHLLCLNLTKPP
YG-----------RWECPWHDCSQ--CGAPASSLCDFCPSSFCRDHEAGALTSSALEGRPCCPGHDPASPL---------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Oryzias_latipes_NSD3
-------------------------------------------------------------MDFSFSFMQGIMGNTIQQP
PQLIDSANIRQD-GTCDTGSDPGEDSGP-SYDASL--DAEFPYPPSASEVMPQLPNGYPPSLGLYEPQTKF-MYSQFPNG
SANGYGALRSYGEHGLLPGEGTVLRGPGLQERPLSPVSPPLPTHHPHLHPHHLHPHHHSFQSNPPHIQTHSHPHSPPPLP
LPSQHHLLQTPHIMTHNLPPPPPLHLPSSSPPPSLVDSTPSSQPAHIPSNTPGGVLKKTSSPEIKLKIIKTYQNGKELFE
SALCGDLQELQKESQKNEAVLKQRRHERKKEKRKRSARLQAQELKQD---PSP---APPGTTEQP---------------
--------------------------------------EEEQVQLQQKETPLIQTEKPQKTVIETEPKTPKVSKVHHPSV
IQETGICKEFVIGDLVWSKVGTYPWWPCMVSSDPQMKVHTRIN-TRGH---------REYHVQFFGSVAERAWIHEKRIV
VYQGKQQFDELQAETLRKATNPVERQKLLKPIPQRERSQWEVGVGHAEDAFLMTRQERI---------------------
---------------------DNYTFIYVDPDPNEAQQ--SKKPSIRPE-KRNRRSSGSVTKKEDRCVKSPDREQQQPQQ
QPQPPRRQQPRRRCSVTNTEDSSQASTEERSQKADQRKASSPRLNAGC--------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------ETQLQQDSSPPVR-A
WKTAAARKLLPLSIT---MKRLNVEITKCDWPLLQKKTSLSPKRA--------------------NAEEKEERGEREARQ
PDLGYCSPEDSRAKPEPSPEEEEDADEGEEEGD-----------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------ERRGSPASQRSEEGGNQQ
PS----SPGSQDSSPQGSQ-------------------------------------------------------------
--------------------------------------------------------------ERKLQRRSIRSKSESERG
TDP-VPKKKTKKEQAEMAPETTLKTG---------------------------------------SQKGASEISDACKPL
KKRSRASTDVEMA-SSQYRDTSDSDSRGLSDPQGLFGKSLDSPAA-ADADASDTQSVDSGLSRQDSSNEKRDTVCQICEA
YGE-GLMVCEGDCSRQFHPECLGLSAPPDGRFTCLECKNSNHPCFSCKTTGQ------EVSRCSAPGCSCYYHEDCVWKH
PGTTSSPGGGFCCPQHSCSTCCLER-------DLQRASKGRLIHCIRCPTAYHTSDVCMAAGSVILTHHIMICSNHGST-
KKNGLLSSPVNVGWCFLCARGLLVQDLTDTILSSYAYKSHYLLTESNR-AEL-KLPMIPSPSSATKKNVGK--GGKLLCC
DSCPASFHPECLEM-DMPEG---AWSCSDCRA---------------GKKPHYKQIVWVKLGNYR-WWPAEICNPRLVPS
NIQSLRHDIGDFPVFFFGSHDYYWINQGRVFPYVENDK-NFVTGQI--NINKTFKNALEEAARRFQELKAQRESREALEQ
ERNSRKPPPYKVIKSNKPVGKVQMHVADLSEIPRCNCKPVDEHPCSIDSQCLNRMLQYECHPQVCPAGDNCENQNFTKRL
YAETEVVKTE-GRGWGLQTNQALRK------------------GDFVAEYVGEVIDSEECQQRIKRAHENHVTNFYMLTL
TKDRVIDAGPKGNSARFINHSCNPNCETQKWTVNGDVRIGIFALCDIEAG-TELTFNYNLHCVGNR-RTSCHCGSENCSG
FLGVQPTSA-----LVMEKEEKARNAKLKPKKRKLRLE-GKHTHEYFCFCCGDGGELVMCDRKDCPKAYHLLCLNLTKPP
YG-----------RWECPWHDCSV--CGSPASSHCDFCPRSFCTDHEAGALTPSSLDERPCCSSHNPLSPLGSSGS-SQR
HSSTLSPVRVKEEPEGEQAAAE----------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Lepisosteus_oculatus_NSD3
-------------------------------------------------------------MDFSFSFMQGIMGNTIQQP
PQLIDSANIRQE-DVYDAGSDNGEDGGPSAYETAL--ESGFSYPPSAAEDLPVVTNGYPPNVSLYEPQAKYAMYSQFPNG
SANGYSAIRSYSDHCLLQGENTVLRAPVVQEKPPSPSSPSATHHHHPHHQPQQQQQQHHHHHHHP---------------
-----HPHPPPPHMNPSVLPPPPPLLLPSSPPPSLATIITS-----PPHPQPPATPKKTSSPEIKLKIIKTYQNGRELFE
SSLCGDLLHEFQASEAS-----RRRHERKKEKRKKSSRHSLHRDPEEQ-QQQHELCVPEPAPEPV---------------
--------------------------------------PEPLCEPLDVHRPKLEFSPRNRTCPEAEPKEHKIQK-HFPTV
ITGTGCCKDHEVGDLVWAKVGTYPWWPCMVSCDPQSDVHTRIN-TRGH---------REYHVQFFGSVPERAWIHEKRVV
VYQGRHQFEQLQADTLRRASNPAERHKLLKPIPQRERAQWEVGIGHAEDAFQMTREERI---------------------
---------------------ENYTFIYVDKEPETSPPP-AEKPTSKADNRRARRTRSAVSSPRPDP-----SGEVSSAR
PGLPPRRQQPRRQCSMTNSEEP--PQPAQPEQDEQQPRCPVPQNQPSE--------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------EPKDQGAQQPPVKTA
WKTAAARKLLPLSIT---MKKLNVEIQKCDWPLPRDRTPSPQES------------------------------EGEDKP
SDQPVCPPRGASSKPEMSSKEQERLVSPVGR-------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------------RSDPG-MVQ
HS----STAEVSSG------------------------------------------------------------------
------------------------------------------------------------LLERKQQRRSVRSRSESEKG
TDP-VPKKKMKKEQTEMVPQAALKTG---------------------------------------SQKGASEISDSCKPL
KKRSRASTDVEMA-SYQYRDTSDSDSRGLNDSQVGFGKRSDSPTA-ADADASDAQSVDSSLSRQGTSTTKKDTVCQICEN
FGD-TLVSCEGDCSRLFHLECLGLTSLLEGKFTCMECKNGAHSCFSCKASGS------DVKRCSVSGCGRFYHESCVRKH
ANATFESKG-FRCPQHSCATCALER-------DMHKASKGRMMRCIRCPTAYHTGDSCFAAGSVVITPHIIICSNHSSS-
KKNGHITSPVNVGWCFVCARGLLVQDNSDNIFSSYAYKSHYLLTESNR-AELMKLPMIPSSSSATKKNCGK--GGRLLCC
ESCPASFHPECLNI-EMPDG---IWFCNECRI---------------GKKPHYKQIVWVKLGNYR-WWPAEICNPRLVPF
NIQTLKHDIGDFPVFFFGSHDYYWINQGRVFPYVEGDK-NFADGQI--GINKTFKKALEEAAKRFQELKAQRESKEALEQ
ERSSRKPPPYKFIKSNKPVGKVQIHVADLSEIPRCNCKPTDENPCSLDSECLNRMLQYECHPQVCPAGENCQNQCFTKRL
YPETEVIKTE-GRGWGLKTKKSLKK------------------GEFVTEYVGELIDSEECRQRIKHAHENHVTNFYMLTL
TKDRVIDAGPKGNYSRFMNHSCSPNCETQKWTVNGDVRVGLFALCDIETE-TELTFNYNLDCLGNG-RTTCHCGAENCSG
FLGVRPKSA-----VVIEKEEKAKNAKLKAKKRKIKPE-AKQNHEYFCFCCGEGGELVMCDKKDCPKAYHLLCLNLTKPP
YG-----------RWECPWHQCSV--CGRSSISFCEFCPSSFCKDHEKGALVPSALEGRLCCSSHNPKNPLT--------
-PESLNKVKVKLEPLDPPDAMGE---------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Latimeria_chalumnae_NSD3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------MYIAINTSCKLPFFSPQMKEHLPA---------------
--------------------------------------VVK---------------------------------------
---MNVEVIYQVGDLVWSKVGTYPWWPCMVSLDPQLQVHTKTN-ARGG---------REYHVQFFGSIPERAWVYEKRVQ
EYKGHSQYDQLLAEAARKATNHAEKQKILKPIPQRERAQWEVGIAHAEEALKMTKEARI---------------------
---------------------EQYTFIYVDEEPGAPASTEKHNCA-KTEAKKGRKHRTAMSP------------------
------------VSEQPTVEEEPQMSPSTEGRRQRLRRQSVVVEP-----------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------PIKMV
WKTAAARKSLPASLI---MQMGNQEGQNHETPLTENKNLVLSIQG----------------------------SGADGRL
TEKFN-ATKGATNKTETDK-GQDKHI------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------VTPASQKNERAS
LQ---HTISETASG---SL-------------------------------------------------------------
--------------------------------------------------------------EKKQQRRSVRSRSESERS
ADA-VPKKKVKKEQVEILPQAAVKTGSQKEDVFSFHDGGCRLV-----------------LKPVVWRLGASEISDSCKPL
KKRSRASTDVEVT-SLTYRDTSDSDSRGLNEVQVGFGKSADSPSAVADAEASDSQSVDSSLSRRGTGTTKKDTVCQICAS
FGE-SLVTCEGECYRLFHMECLGLTALPEGKFICIECKAGSHTCFSCKVPGT------DVKRCSVNACGRFFHESCARKY
STSMFESKG-FRCPQHCCTTCSIDK-------DIHKASKGRMMRCLQCPVAYHTGDSCVVAGSVVLTPHIIICSDHS---
KRSSHSVPAVNVGFCFVCSRGLLVQDLSDPLLSAYANKSHYLLSESYR-AELMKLPMIPSSSSASKKKVEK--GGRLLCC
ESCPASFHPECLNI-EMPEG---SWYCNECKA---------------GKKLHYKQIVWVKLGNYR-WWPAEICSPRSVPH
NIQGIKHDIGDFPVFFFGSHDYYWVHRGRVFPYVEGDK-SFAEGQI--SGSKTFKKALDEAAKRFQELKAQRESKEALEN
ERNSRKPIPYKHIRTNKPVGKVQIHIADLSEIPRCNCKPDDENPCGLDSECLNKMLQYECHPQVCPAAEHCQNQSFSKRL
YPETEVIKTE-GRGWGLQTKCNIRK------------------GEFVNEYVGELIDEQECRSRIKKAHENNVTNFYMLTL
TKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDVRVGLFALCDISAG-TELTFNYNLDCLGNG-RTKCYCAAENCSG
FLGVRPKTA-----CATATEEKAKIAKLKQKKRKIKLE-RSQMHEDYCFHCGDGGELVMCDKKDCPKAYHLLCLNLTKPP
VG-----------RWECPWHQCSE--CNSPAVSHCEFCPSSFCKDHEKGSLVSSALEGRLCCSKHDPKCPVA--------
-PESWAWMKCKTEPQDTGEEPTE---------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Pan_troglodytes_NSD3
-------------------------------------------------------------MDFSFSFMQGIMGNTIQQP
PQLIDSANIRQE-DAFDNNSDIAEDGGQTPYEATL--QQGFQYP-ATTEDLPQLTNGYPSSISVYETQTKYQSYNQYPNG
SANGFGAVRNFSPTDYYHSEIPNTRPHEILEKPSPPQP------------------------------------------
--------------------------------------------PPPPSVPQTVIPKKTGSPEIKLKITKTIQNGRELFE
SSLCGDLLNEVQASEHT-----KSKHESRKEKRKKSNKHDSSRSEERKSHKIPKLEPEEQNRPNE---------------
--------------------------------------RVDTVSEKPREEPVLKEEAPVQPILSSVPTTE----------
---VSTGVKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKIN-TRGA---------REYHVQFFSNQPERAWVHEKRVR
EYKGHKQYEELLAEATKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERI---------------------
---------------------EQYTFIYIDKQPEEALSQAKKNVASKTEVKKTRRPRSVLNT------------------
------------QPEQTNAGEVASSLSSTEIRRHSQRRHTSAEEEE----------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------PPPVKIA
WKTAAARKSLPASIT---MHKGSLDLQKCNMSPVVKIEQVFALQN----------------------------ATGDGKF
IDQFVYSTKGIGNKTEISVRGQDRLI------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------ISTPNQRNEKPT
QS---VSSPEATSGSTGSV-------------------------------------------------------------
--------------------------------------------------------------EKKQQRRSIRTRSESEKS
TEV-VPKKKIKKEQVETVPQATVKTG---------------------------------------LQKGASEISDSCKPL
KKRSRASTDVEMT-SSAYRDTSDSDSRGLSDLQVGFGKQVDSPSATADADVSDVQSMDSSLSRRGTGMSKKDTVCQICES
SGD-SLIACEGECCKHFHLECLGLTSLPDSKFICMECKTGQHPCFSCKVSGK------DVKRCSVGACGKFYHEACVRKF
PTAIFESKG-FRCPQHCCSACSMEK-------DIHKASKGRMMRCLRCPVAYHSGDACIAAGSMLVSSYILICSNHS---
KRSSNSS-AVNVGFCFVCARGLIVQDHSDPMFSSYAYKSHYLLNESNR-AELMKLPMIP-SSSASKKKCEK--GGRLLCC
ESCPASFHPECLSI-EMPEG---CWNCNDCKA---------------GKKLHYKQIVWVKLGNYR-WWPAEICNPRSVPL
NIQGLKHDLGDFPVFFFGSHDYYWVHQGRVFPYVEGDK-SFAEGQT--SINKTFKKALEEAAKRFQELKAQRESKEALEI
EKNSRKPPPYKHIKANKVIGKVQIQVADLSEIPRCNCKPADENPCGLESECLNRMLQYECHPQVCPAGDRCQNQCFTKRL
YPDAEIIKTE-RRGWGLRTKRSIKK------------------GEFVNEYVGELIDEEECRLRIKRAHENSVTNFYMLTV
TKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDVRVGLFALCDIPAG-MELTFNYNLDCLGNG-RTECHCGADNCSG
FLGVRPKSA-----CASTNEEKAKNAKLKQKRRKIKTE-PKQMHEDYCFQCGDGGELVMCDKKDCPKAYHLLCLNLTQPP
YG-----------KWECPWHQCDE--CSSAAVSFCEFCPHSFCKDHEKGALVPSALEGRLCCSEHDPMAPVS--------
-PEYWSKIKCKWESQDHGEEVKE---------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Gorilla_gorilla_NSD3
-------------------------------------------------------------MDFSFSFMQGIMGNTIQQP
PQLIDSANIRQE-DAFDNNSDIAEDGGQTPYEATL--QQGFQYP-ATTEDLPPLTNGYPSSISVYETQTKYQSYNQYPNG
SANGFGAVRNFSPTDYYHSEIPNTRPHEILEKPSPPQP------------------------------------------
--------------------------------------------PPPPSVPQTVIPKKTGSPEIKLKITKTIQNGRELFE
SSLCGDLLNEVQASEHM-----KSKHESRKEKRKKSNKHDSSRSEERKSHKIPKLEPEEQNRPNE---------------
--------------------------------------RVDTVSEKPREEPVLKEEAPVQPILSSVPTTE----------
---VSTGVKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKIN-TRGA---------REYHVQFFSNQPERAWVHEKRVR
EYKGHKQYEELLAEATKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERI---------------------
---------------------EQYTFIYIDKQPEEALSQAKKNVASKTEVKKTRRPRSVLNT------------------
------------QPEQTNAGEVASSLSSTEIRRHSQRRHTSAEEEE----------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------PPPVKIA
WKTAAARKSLPASIT---MHKGSLDLQKCNMSPVVKIEQVFALQN----------------------------ATGDGKF
IDQFVYSTKGIGNKTEISVRGQDRLI------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------ISTPNQRNEKPT
QS---VSSPEATSGSTGSV-------------------------------------------------------------
--------------------------------------------------------------EKKQQRRSIRTRSESEKS
TEV-VPKKKIKKEQVETVPQATVKTG---------------------------------------LQKGASEISDSCKPL
KKRSRASTDVEMT-SSAYRDTSDSDSRGLSDLQVGFGKQVDSPSATADADVSDVQSMDSSLSRRGTGMSKKDTVCQICES
PGD-SLIPCEGECCKHFHLECLGLTSLPDSKFICMECKTGQHPCFSCKVSGK------DVKRCSVGACGKFYHEACVRKF
PTAIFESKG-FRCPQHCCSACSMEK-------DIHKASKGRMMRCLRCPVAYHSGDACIAAGSMLVSSYILICSNHS---
KRSSNSS-AVNVGFCFVCARGLIVQDHSDPMFSSYAYKSHYLLNESNR-AELMKLPMIP-SSSASKKKCEK--GGRLLCC
ESCPASFHPECLSI-EMPEG---CWNCNDCKA---------------GKKLHYKQIVWVKLGNYR-WWPAEICNPRSVPL
NIQGLKHDLGDFPVFFFGSHDYYWVHQGRVFPYVEGDK-SFAEGQT--SINKTFKKALEEAAKRFQELKAQRESKEALEI
EKNSRKPPPYKHIKANKVIGKVQIQVADLSEIPRCNCKPADENPCGLESECLNRMLQYECHPQVCPAGDRCQNQCFTKRL
YPDAEIIKTE-RRGWGLRTKRSIKK------------------GEFVNEYVGELIDEEECRLRIKRAHENSVTNFYMLTV
TKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDVRVGLFALCDIPAG-MELTFNYNLDCLGNG-RTECHCGADNCSG
FLGVRPKSA-----CASTNEEKAKNAKLKQKRRKIKTE-PKQMHEDYCFQCGDGGELVMCDKKDCPKAYHLLCLNLTQPP
YG-----------KWECPWHQCDE--CSSAAVSFCEFCPHSFCKDHEKGALVPSALEGRLCCSEHDPMAPVS--------
-PEYWSKIKCKWESQDHGEEVKE---------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Otolemur_garnettii_NSD3
-------------------------------------------------------------MDFSFSFMQGIMGNTIQQP
PQLIDSANIRQE-DAFDNNSDIAEDGGQIPYEATL--QQGFQYP-STTEDLPPLTNGYPPSISIYETQTKYQSYNQYPNG
SANGFGAVRNFSPTDYYHSEIPNTRPQEILEKPSPPQP------------------------------------------
--------------------------------------------PPPPSVPQTVIPKKTGSPEIKLKITKTIQNGRELFE
SSLCGDLLNEVQASEHT-----KSKHESRKEKRKKSNKHDSSRSEERKSHKIPKLEPEEQNRPNE---------------
--------------------------------------RVDPASEKPREDPVLKGEAPVQPILSSVPTTE----------
---VSTGVKFQVGDLVWSKVGTYPWWPCMVSSDPLLEVHTKIN-TRGA---------REYHVQFFSNQPERAWVHEKRVR
EYKGHKQYEELLAEATKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERV---------------------
---------------------EQYTFIYIDKQPEEALSQAKKSVAAKAEAKKTRRPRSVLTT------------------
------------QPEQTDAGEAASSPSGSETRRHSQRRHTSVEEEE----------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------PPPVKIA
WKTAAARKSLPASIT---MHKGSLDLQKCNMSPVVKIEQVFALQN----------------------------ATGDGKF
IDQFVYSTKGIGNKTEISVRGQDRLI------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------ITAPNQRNEKPT
QN---TSSPEATSGSTGSV-------------------------------------------------------------
--------------------------------------------------------------EKKQQRRSIRTRSESEKS
TEV-VPKKKIKKEQVEMVPQATLKTG---------------------------------------LQKGASEISDSCKPL
KKRSRASTDVEMT-SSAYRDTSDSDSRGLSDLQVGFGKQGDSPSATADADVSDVQSVDSSLSRRGVGMSKKDTVCQICES
SGD-SLTPCEGECCKHFHLECLGLTSVPDGKFICTECKTGQHPCFSCKVSGK------DVKRCSVGACGKFYHEACVRKF
PTAIFESKG-FRCPQHCCSACSMEK-------DIHKASKGRMLRCLRCPVAYHSGDACVAAGSVFVSSCILICSGHA---
RRNSSSAAAVNVGFCFVCARGLIVQDHSDPMFSSYAYKSHYLLNESNR-AELMKLPMIP-SSSASKKKCEK--GGRLLCC
DSCPASFHPECLSM-DVPEG---CWNCSDCRT---------------GKKLHYKQIVWVKLGNYR-WWPAEICNPRAVPL
NIQGLKHDLGDFPVFFFGSHDYYWVHQGRVFPYIEGDK-SFAEGQT--SINKTFKKALEEAAKRFQELKAQRESKEALEI
EKNSRKPPPYKHIKANKVIGKVQIQVADLSEIPRCNCKPADENPCGLESECLNRMLQYECHPQVCPAGERCQNQCFTKRL
YPDAEIIKTE-RRGWGLRTKRSIKK------------------GEFVNEYVGELIDEEECRLRIKRAHENSVTNFYMLTV
TKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDVRVGLFALCDIPAG-MELTFNYNLDCLGNG-RTECHCGADNCSG
FLGVRPKSA-----CASTNEEKAKNAKLKQKRRKVKTE-PKQMHEDYCFQCGDGGELVMCDKKDCPKAYHLLCLNLTQPP
YG-----------KWECPWHQCAE--CGSAAVSFCEFCPRSFCKDHEKGALVPSALEGRLCCSEHDPRSPVS--------
-PEYWNKIKCKWESQDRGEEVKE---------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Macaca_mulatta_NSD3
-------------------------------------------------------------MDFSFSFMQGIMGNTIQQP
PQLIDSANIRQE-DAFDNNSDIAEDGGQTPYEATL--QQGFQYP-ATTEDLPPLTNGYPSSISVYETQTKYQSYSQYPNG
SANGFGAARNFSPTDYYHSEIPNTRPHEILEKPSPPQP------------------------------------------
--------------------------------------------PPPPSVPQTVIPKKTGSPEIKLKITKTIQNGRELFE
SSLCGDLLNEVQASEHT-----KSKHESRKEKRKKSNKHDSSRSEERKSHKIPKLEPEEQNRPNE---------------
--------------------------------------RVDTVSEKPREDPVLKEEAPVQPILSSVPTTE----------
---VSTGVKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHSKIN-TRGA---------REYHVQFFSNQPERAWVHEKRVR
EYKGHKQYEELLAEATKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERI---------------------
---------------------EQYTFIYIDKQPEEALSQAKKNVASKTEVKKTRRPRSVLNT------------------
------------QPEQTSAGEVASSLSSTEIRRHSQRRHTSAEEEE----------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------PPPVKIA
WKTAAARKSLPASIT---MHKGSLDLQKCNMSPVVKIEQVFALQN----------------------------ATGDGKF
IDQFVYSTKGIGNKTEISVRGQDRLI------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------ISTPNQRSEKPT
QS---ISSPEATSGSTGSV-------------------------------------------------------------
--------------------------------------------------------------EKKQQRRSIRTRSESEKS
TEV-VPKKKIKKEQVETVPQATVKTG---------------------------------------LQKGASEISDSCKPL
KKRSRASTDVEMT-SSAYRDTSDSDSRGLSDLQVGFGKQVDSPSATADADVSDVQSMDSSLSRRGTGMSKKDTVCQICES
SGD-SLIPCEGECCKHFHLECLGLTSLPDSKFVCMECKTGQHPCFSCKVSGK------DVKRCSVGACGKFYHEACVRKF
PTAIFESKG-FRCPQHCCSACSMEK-------DIHKASKGRMMRCLRCPVAYHSGDACIAAGSMLVSSYILICSNHS---
KRSSNSSAAVNVGFCFVCARGLIVQDHSDPMFSSYAYKSHYLLNESNR-AELMKLPMIP-SSSASKKKCEK--GGRLLCC
ESCPASFHPECLSI-EMPEG---CWNCNDCKA---------------GKKLHYKQIVWVKLGNYR-WWPAEICNPRSVPL
NIQGLKHDLGDFPVFFFGSHDYYWVHQGRVFPYVEGDK-SFAEGQT--SINKTFKKALEEAAKRFQELKAQRESKEALEI
EKNSRKPPPYKHIKANKVIGKVQIQVADLSEIPRCNCKPADENPCGLESECLNRMLQYECHPQVCPAGDRCQNQCFTKRL
YPDAEIIKTE-RRGWGLRTKRSIKK------------------GEFVNEYVGELIDEEECRLRIKRAHENSVTNFYMLTV
TKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDVRVGLFALCDIPAG-MELTFNYNLDCLGNG-RTECHCGADNCSG
FLGVRPKSA-----CASTTEEKAKNAKLKQKRRKIKTE-PKQMHEDYCFQCGDGGELVMCDKKDCPKAYHLLCLNLTQPP
YG-----------KWECPWHQCDE--CSSAAVSFCEFCPHSFCKDHEKGALVPSALEGRLCCSEHDPMAPVS--------
-PEYWSKIKCKWESQDHGEEVKE---------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Bos_taurus_NSD3
-------------------------------------------------------------MDFSFSFMQGIMGNTIQQP
PQLIDSANIRQE-DAFDNNSDIVEDGGQTPYEATL--QQGFQYP-PTTEDLPPLTNGYPPSISMYETQTKYQSYNQYPNG
SANGFGTVRNFSPSDYYHSEIPNTRPHEILEKPSPPQPP-----------------------------------------
--------------------------------------------PPPPSVPQTVIPKKTGSPEIKLKITKTIQNGRELFE
SSLCGDLLNEVQASEHT-----KSKHESRKEKRKKSNKHDSSRSEERKSHKIPKLEPEEQNRPNE---------------
--------------------------------------RVDPVSEKPREDPVLKEETPVQPMLPSVPTAE----------
---ASAGVKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKIN-TRGA---------REYHVQFFSNQPERAWVHEKRVR
EYKGHKQYEELLAEATRQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALTMTREERI---------------------
---------------------EQYTFIYIDKQPEETLSQAKKNVVSKAEVKKPRRPRSVLNV------------------
------------QPEQTNAGEAASSPSGTEMRRHSQRRHTGVDEDE----------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------PPPVKVA
WKTAAARKSLPASIT---MHKGSLDLQKCNMSPVVKIEQVFALQN----------------------------ATGDGKF
IDQFVYSTKGIGNKTEISVRGQDRLI------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------ISTPNQRNEKAT
QN---MSSPEATSGSAGSV-------------------------------------------------------------
--------------------------------------------------------------EKKQQRRSIRTRSESEKS
TEV-VPKKKIKKEQVETVPQATVKTG---------------------------------------LQKGASEISDSCKPL
KKRSRASTDVEMA-GSTYRDTSDSDSRGLSDLQAGFGKQVDSPSATAEADVSDVQSVDSSLSRRGTGMSRKDTVCQICES
SGD-SLIPCEGECCKHFHLECLGLSSPPDGKFVCVECKTGQHPCFSCKVSGA------DVKRCSVSACGKFYHEACVRKF
PTAVFESKG-FRCPQHCCSACSMEK-------DIHKASKGRMVRCLRCPVAYHSVDACIAAGSTLVSSCVLICSNHS---
TRSSGSSSAVNVGFCFVCARGLIVQDHSDPMFSSYAYKSHYLLNESNR-AELMKLPMIP-SSSASKKKCEK--GGRLLCC
ESCPASFHPECLSI-ETPEG---CWNCNDCKA---------------GKKLHYKQIVWAKLGNYR-WWPAEICNPRSVPL
NIQGLKHDLGDFPVFFFGSHDYYWVHQGRVFPYVEGDK-SFADGQT--SINKTFKKALEEAAKRFQELKAQRESKEALEI
EKSSRKPPPYKHIKANKVIGKVQIQVADLSEIPRCNCKPADENPCGLESECLNRMLQYECHPQVCPAGERCQNQCFTKRL
YPDAEVIRTE-RRGWGLRTKRSIKK------------------GEFVNEYVGELIDEEECRLRIKRAHEN----------
-SDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDVRVGLFALCDIPAG-MELTFNYNLDCLGNG-RTECHCGADNCSG
FLGVRPKSA-----CASTAEEKAKNAKLKPKRRKIKTE-PKQLHEDFCFQCGDGGELVMCDRKDCSKAYHLLCLNLPQPP
YG-----------KWECPWHQCDE--CSAAAVAFCEFCPRSFCKDHEKGALVPSALEGRLCCSEHDPASPVS--------
-PEYWSKIKCKLESQDHGEEVKE---------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Felis_catus_NSD3
-------------------------------------------------------------MDFSFSFMQGIMGNTIQQP
PQLIDSANIRQE-DAFDNNSDIVEDGGQTPYEATL--QQGFQYP-PTTEDLPPLTNGYPPSISMYETQTKYQSYNQYPNG
SANGFGAVRNFSPTDYYHSEIPNTRPHEILEKPSPPQP------------------------------------------
--------------------------------------------PPPPSVPQTVIPKKTGSPEIKLKITKTIQNGRELFE
SSLCGDLLNEVQASEHT-----KSKHESRKEKRKKSNKHDSSRSEERKSHKIPKLEPEEQNRPNE---------------
--------------------------------------RIDTVSEKPRDDPVLKEEPPVQPILSSVPTTE----------
---VSAGVKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKIN-TRGA---------REYHVQFFSNQPERAWVHEKRVR
EYKGHKQYEELLAEATKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERI---------------------
---------------------EQYTFIYIDKQPEEALSQAKKNVASKAEVKKTRRPRSVLNT------------------
------------QPEQTDAGEVASSPSSTEIRRQSQRRHTSVEEEE----------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------PPPVKIA
WKTAAARKSLPASIT---MHKGSLDLQKCNMSPVVKIEQVFALQN----------------------------ATGDGKF
IDQFVYSTKGIGNKTEISVRGQDRLI------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------ISTPNQRSEKAT
QN---ISSPEATSGPTGSV-------------------------------------------------------------
--------------------------------------------------------------EKKQQRRSIRTRSESEKS
TEV-VPKKKIKKEQVETVPQATVKTG---------------------------------------LQKGASEISDSCKPL
KKRSRASTDVEMT-SSAYRDTSDSDSRGLSDLQVGFGKQVDSPSATADVDVSDVQSVDSSLSRRGIGISKKDTVCQICES
SGD-SLIPCEGECCKHFHLECLGLASLPDGKFICVECKTGQHPCFSCKVSGT------DVKRCSVGACGKFYHEACVRKF
PTAIFESKG-FRCPQHCCSACSMEK-------DIYKASKGRMMRCLRCPVAYHSGDACIAAGSIFVSSYILICSNHS---
KRSSSSSSAINVGFCFVCARGLIVQDHSDPMFSSYAYKSHYLLNESNR-AELMKLPMIP-SSSASKKKCEK--GGRLLCC
ESCPASFHPECLSI-EMPEG---CWNCNDCKA---------------GKKLHYKQIVWVKLGNYR-WWPAEICNPRSVPL
NIQGLKHDLGDFPVFFFGSHDYYWVHQGRVFPYVEGDK-SFAEGQT--SINKTFKKALEEAAKRFQELKAQRESKEALEI
EKNSRKPPPYKHIKANKVIGKVQIHVADLSEIPRCNCKPADENPCGLESECLNRMLQYECHPQVCPAGERCQNQCFTKRL
YPDAEIIKTE-RRGWGLRTKRSIKK------------------GEFVNEYVGELIDEEECRLRIKRAHENSVTNFYMLTV
TKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDVRVGLFALCDIPAG-MELTFNYNLDCLGNG-RTECHCGAENCSG
FLGVRPKPT-----CASTTEEKAKNAKLKQKRRKIKAE-PKQMHEDYCFQCGDGGELVMCDKKDCPKAYHLLCLNLTQPP
YG-----------KWECPWHQCGE--CGSAAVSFCEFCPRSFCKDHREGALVPSALEGRLCCSEHDPESPVS--------
-AEYWSKIKCKLESQDRGEDLRE---------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Canis_lupus_familiaris_NSD3
-------------------------------------------------------------MDFSFSFMQGIMGNTIQQP
PQLIDSANIRQE-DAFDNNSDIVEDGGQTPYEATL--QQGFQYP-PTTEDLPPLTNGYPPSISMYETQTKYQSYNQYPNG
SANGFGAVRNFSPTDYYHSEIPNTRPHEILEKPSPPQL------------------------------------------
--------------------------------------------PPPPSVPQTVIPKKTGSPEIKLKITKTIQNGRELFE
SSLCGDLLNEVQASEHT-----KSKHESRKEKRKKSNKHDSCRSEERKSHKIPKLEPEEQNRPNE---------------
--------------------------------------RVDTVSEKPREEPVPKEEPPVQPILSSVPTTE----------
---VSAGVKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKIN-TRGA---------REYHVQFFSNQPERAWVHEKRVR
EYKGHKQYEELLAEATKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERI---------------------
---------------------EQYTFIYIDKQPEEALSQGKKNVASKAEVKKTRRPRSVLNT------------------
------------QLEQTNAGEVASSLSSTEIRRQSQRRHTSVEEEE----------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------PPPVKIA
WKTAAARKSLPASIT---MHKGSLDLQKCNMSPVVKIEQVFALQN----------------------------ATGDGKF
IDQFVYSTKGIGNKTEISVRGQDRLI------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------ISTPNQRNEKAT
QN---ISS-EATSGPTGSV-------------------------------------------------------------
--------------------------------------------------------------EKKQQRRSIRTRSESEKS
TEV-VPKKKIKKEQVETVPQATVKTG---------------------------------------LQKGASEISDSCKPL
KKRSRASTDVEMT-SSAYRDTSDSDSRGLSDLQVGFGKQVDSPSATADADVSDVQSVDSSLSRRGIGVSKKDTVCQICES
SGD-SLIPCEGECCKHFHLECLGLASVPDGKFICIECKTGQHPCFSCKVSGT------DVKRCSVGACGKFYHEACVRKF
PTAIFESKG-FRCPQHCCSACSMEK-------DIYKASKGRMMRCLRCPVAYHSGDACIAAGSIFISSYNLICSNHS---
KRKSSSSSAINVGFCFVCARGLIVQDHSDPMFSSYAYKSHYLLNESNR-AELMKLPMIP-SSSASKKKCEK--GGRLLCC
ESCPASFHPECLSI-EMPEG---CWNCNDCKA---------------GKKLHYKQIVWVKLGNYR-WWPAEICNPRSVPL
NIQGLKHDLGDFPVFFFGSHDYYWVHQGRVFPYVEGDK-SFAEGQT--SINKTFKKALEEAAKRFQELKAQRESREALEI
EKNSRKPPPYKHIKANKVIGKVQIHVADLSEIPRCNCKPADENPCGLESECLNRMLQYECHPQVCPAGERCQNQCFTKRL
YPDAEIIKTE-RRGWGLRTKRSIKK------------------GEFVNEYVGELIDEEECRLRIKRAHENSVTNFYMLTV
TKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDIRVGLFALCDIPAG-MELTFNYNLDCLGNG-RTECHCGAENCSG
FLGVRPKST-----CVSTTEEKAKNAKLKQKRRKIKAE-PKQMHEDYCFQCGDGGELVMCDKKDCPKAYHLLCLNLTQPP
YG-----------KWECPWHQCEE--CSSAAVSFCEFCPHSFCKDHEEGALVPSALEGRLCCSEHDPACPVS--------
-AEYWSKIKCKLESQDHGEELKE---------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-
>Callorhinchus_milii_NSD3
-------------------------------------------------------------MDLSYSFMKGIMGNTIQLP
QQLIDSANMRQVPDVLNAASGIGEDRGQ-TYEASL--QQGFIYPASSADSIPPVTNGYAS-VNLYDAPNKYAGYSQLPNG
SANGYGTYRNLASADYYAVENCIVKPPEIQEKAPSPPA------------------------------------------
--------------------------------------------------SEPATPKKTGSPEIKLRITKTYHNGKALFE
SSLCGDLLNEEQAQSQAQSP--LAAAREQKREKKKRKKHDSCSGEEQTRKKVIKAEPEEHKVSPF---------------
--------------------------------------GGVDSTGTMGRIAFSHYKYSIQPALGSLPCVG----------
-----GVPQYQIGDLVWSKVGTYPWWPCMVSSDPLLQIHTKIN-TRGA---------REYHVQFFGSIPERAWVHEKRVA
PYKGCSQYEILVAETARQASSTAEKQKILKPIAQRVRPQWDVGIAQVEEALKMTLEDRI---------------------
---------------------AQYTFIYVDPPLETSLESNKSPATLKSEVKRSRKPRMFPRA------------------
--------------EQEESERHLDSPSPASAGDGNGHGHPGEREAP----------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------------------KMA
WRTAAARKSLPPSLANLKVEKRNGGSSDCDVLPVAKSDQVLSVQE--------------------------------QGT
PGTCVNQYLGTCIKTDVSGREVDKAG------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------------KPTPNQKPF
VS--------GVNRLPGSL-------------------------------------------------------------
--------------------------------------------------------------ERKQQRRCVRSRSESEKS
VEA-VPKKKMRKEQVRMLLLLFVGAS---------------------------------------------ELSDACKPL
KKRSRASTDVEMT-SSSYREVNDSDCRG----LVSEGAIRDSIGACIEISVESSISR----SQRCVRTVLRPLSLKICEK
PGE-SLVPCEGECCRVFHLECLGLAELPNGKFTCMECTTGNHTCFSCKVSGK------IVKRCSVNSCGRFYHESCLRSY
STAMFEGKG-FRCPLHCCLACLADNR------EIAKATKGRMLRCLRCPTAYHTGEGCIAAGSLVLSNHSIICNNHSSAK
KGNRAALSHVNVSWCFICARGVIEQHQSESLFSSYAYKSHYLLSESNRSAELLKLAMIPPSPSATVKKCGK--GGHLLCC
ESCPASFHPECLNI-EMPEG---SWYCNDCKA---------------GKKPRYKEIVWVKLGIYR-WWPAEICNPKSVPL
NIQAMKHHIGEFPVRFFGSNDYYWVHQGRVFPYLEGDKGNVSDGRT-GSINETFKKALEETTKRFRELKALRESKEALEN
ERNERKPPAYRFVKTNKPIGKVQIYTADLSEIPRCNCKPTDESPCGLESECLNRILMYECHADVCPAGEHCQNQSFSKRL
YPDTELVKTE-GRGWGLRTKVDIKK------------------GQFVNEYVGELVDEEECRKRIKHAHENNVTNFYMLTL
TKDRVIDAGPKGNYSRFMNHSCNPNCETQKWTVSGDTRVGLFALCDVRAG-SELTFNYNLDCLGNG-KTICKCGAPNCSG
YLGVRPKTA-----AATANEEKAKNAKKKMKRRKTKMD-VRKMHEDYCYRCGDGGELVMCDKKDCPKAYHLSCLNLTKPP
FG-----------KWECPWHHCDE--CGNPATTFCDFCPNSYCREHQKGSFTACGLDGRLCCSDHEPGFHAEFD------
-RASSVSLPNHSATEDTSEEALE---------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-