>Homo_sapiens_RGS13
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------MSRRNCWICKMCRDESKRP-------------------------------
---------------PSNL-------------------------------------------------------------
----------------------TLEEVLQ---WA-QSFENL-MATK---YGPVVYAAYLKMEHSDENI--QFWMACETYK
KIA--SRWSRISRAKKLYKIYIQPQSPREIN----IDSSTRETIIRNIQE-PTETC---FEEAQKIVYMHMERDSYPRFL
KSEMYQKLLK---------TMQSNNSF-----------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Macaca_mulatta_RGS13
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------MSRRNCWICKVFRDESKRP-------------------------------
---------------PSNL-------------------------------------------------------------
----------------------TLEEVLQ---WA-QSFENL-MATK---YGPVVYAAYLKMEHSDENI--QFWMACETYK
KIA--SRWSRTSRAKKLYRIYIQPQSPREIN----IDNSTRQTIIKNIQE-PTETC---FEEAQKIVYMHMERDSYPRFL
KSEMYQKLLK---------TMQSNNSF-----------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Mus_musculus_RGS13
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------MSRHICWICKLCRDESKRL-------------------------------
---------------PSNL-------------------------------------------------------------
----------------------TLDEVLK---WA-QSLESL-MATK---YGPIVYTAYLKLEHSDENI--KFWMACETYK
KIA--SRRGRISRAKKLYNIYIQPQSPREIN----IDSTTREAIIKSIRE-PTQTC---FEEAQKIVYMHMEMDSYPRFL
KSEMYQQLLK---------TVQSQSS------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Rattus_norvegicus_RGS13
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------MSRHICWICKLCRHESKRL-------------------------------
---------------PSNL-------------------------------------------------------------
----------------------TLDEVLK---WA-QSLESL-MATK---YGPVVYTAYLKLEHSDENI--KFWMACETYK
KIA--SRRGRISRAKKLYNLYIQPQSPREIN----IDSTTREAIIKSIRE-PTQTC---FEEAQKIVYMHMEMDSYPRFL
KSEMYQKLLK---------TVQSKSC------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Homo_sapiens_RGS8
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------MWNTLTRSLSDHPVGKDPQ--------------------------------
--------------------------------------------------------------------------------
--------------------------AMRTGQRQNKGMRTRLGCLSHKSDSCSDFTAILP--------------------
---------DKPNRALK---------------------------------------------------------------
--------------------RLSTEEATRWA----DSFDVL-LSHK---YGVAAFRAFLKTEFSEENL--EFWLACEEFK
KTR--STAKLVSKAHRIFEEFVDVQAPREVN----IDFQTREATRKNLQE-PSLTC---FDQAQGKVHSLMEKDSYPRFL
RSKMYLDLLSQSQRRLS---------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Callithrix_jacchus_RGS8
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------MWSALTRSLSDHPVGKDPQ--------------------------------
--------------------------------------------------------------------------------
--------------------------AMRTGQRQNKGMRTRLGCLSHKSDSCSDFTAILP--------------------
---------DKPNRALK---------------------------------------------------------------
--------------------RLSTEEATRWA----DSFDVL-LSHK---YGVAAFRAFLKTEFSEENL--EFWLACEEFK
KTR--STAKLVSKAHRIFEEFVDVQAPREVN----IDFQTREATRKNMQE-PSLTC---FDQAQGKVHSLMEKDSYPRFL
RSKMYLDLLSQSQRRLS---------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Mus_musculus_RGS8
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------MRTSQRQNKGMRTRLGCLSHKSDSCSDFTAILP--------------------
---------DKPNRALK---------------------------------------------------------------
--------------------RLSTEEATRWA----ESFDVL-LSHK---YGVAAFRAFLKTEFSEENL--EFWLACEEFK
KTR--STAKLVTKAHRIFEEFVDVQAPREVN----IDFQTREATRKNMQE-PSLTC---FDQAQGKVHSLMEKDSYPRFL
RSKMYLDLLSQSQRRLS---------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Gallus_gallus_RGS8
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------M--------------------------------
--------------------------------------------------------------------------------
--------------------------AALLIPRRNRGMRTRLGCLSHKSDSYNDFTAILP--------------------
---------DKPNRALK---------------------------------------------------------------
--------------------RLSTEEATRWA----DSFDVL-LSHK---YGLAAFRAFLKTEFSEENL--EFWLACEDFK
KTR--STAKLAAKAQRIFEEFIDVQAPREVN----IDFQTRELTRRNMQE-PSLSC---FDQAQGKVHSLMEKDSYPRFL
RSKIYTDLLSQTQRRLS---------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Anolis_carolinensis_RGS8
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------MKEDAPRCSDQSLCDHTLGKELQ--------------------------------
--------------------------------------------------------------------------------
--------------------------STRTGQRQNRGMRTRLGCLSHKSDSCSDFTAILP--------------------
---------DKPNRALK---------------------------------------------------------------
--------------------RLSTEEATRWG----DSFDVL-LSHK---YGVAAFRAFLKTEFSEENL--EFWLACEEFK
KTR--STAKLASKAQRIFEEFVDVQAPREVN----IDFQTREVTRRNIQE-PSSSC---FDQAQGKIHSLMEKDSYPRFL
RSKIYTDLLSQTQRRLS---------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Danio_rerio_RGS8_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------MKTRLGCLSNKSDSCSDFSEFLPP-------------------
-------AQERTTRYL----------------------------------------------------------------
--------------------KLSNDEVTRWA----DSFDIL-LSNK---YGLAAFRTFLKTEFSDENI--EFWLACEDYK
KIK--SPAKMMSKANKIYKEFIDVHAPREVN----IDHRTREETKNRLLE-PTPHS---LNEVQAKVYSLMEKDSYPRFI
RSKIYQDLLNRTQIYCQRKSV-----------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Takifugu_rubripes_RGS8_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------SCIVWM--------------------------------
--------------------------------------------------------------------------------
--------------------------PE-----RTPTMKTRLGCLSKKSDSYSDFSEFLPP-------------------
-------AHDTTARWLN---------------------------------------------------------------
--------------------RLSTDEVVRWS----ESFDHL-LSHK---HGLAAFRTFLKSEFSDENI--EFWMACEEYK
KTK--SSTKLVSKANKIYQEFLDIQAPREVN----IDHRTREKTKQSLED-PSPTS---LNEVQAKVYSLMERDSYPRFL
RSKMYKDLVSRAHARGQ---------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Tetraodon_nigroviridis_RGS8_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------M--------------------------------
--------------------------------------------------------------------------------
--------------------------HSLYDPKQDPTMKTRLGCLSKKSDSYSDFSEFLPP-------------------
-------AHETTARCLN---------------------------------------------------------------
--------------------RLSTDEVVRWS----ESFEHL-LSHK---HGLAAFRTFLKSEFSDENI--EFWMACEEYK
KTK--SSTKLVSKANKIYKEFIDTQAPREVN----IDHRTREKTKQSLED-PSPTS---LNEVQAKIYSLMERDSYPRFL
RSKMYQDMVSRAHAQGQRRSV-----------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Gasterosteus_aculeatus_RGS8_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------MKTRLGCLSNKSDSYSDFSEFLPP-------------------
-------AHETTARCL----------------------------------------------------------------
--------------------KVSTDEVVRWS----ESFDHL-LSHK---YGLAAFRTFLKSEFSDENI--EFWMACEEYK
KIK--SSTKLVSKANKIFQEFIDIQAPREVN----IDYRTREKTKQSLED-PSPTS---LNEVQGKVYGLMEKDSYPRFL
RSKMYQDMVNRANAHGQRRSV-----------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Oryzias_latipes_RGS8_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------L--------------------------------
--------------------------------------------------------------------------------
--------------------------AALLQFGRLSTMKTRLGCLSKKSDSYSDFSEFLPP-------------------
-------AHETTARCLNTSH------------------------------------------------------------
------AVTSEQLKQTF---RLSTDEVVRWS----DSFEHL-LSHK---YGLAAFRTFLKSEFSDENI--EFWMACEEYK
KIK--SSTKLLSKANKIFKEFIEVQSPREVN----IDYRTREKTKQSLAD-PTPTS---LNEVQGKIYSLMEKDSYPRFL
RSKMYQDMINRAHAQGQRRSV-----------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Homo_sapiens_RGS1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------MRAAAISTP-------
----------------KLDKMPGMFFSAN---PKELK-GTTHSLLD----------------------------------
--------------------------------------------------------------------------------
-----------------------DKMQKRRPKTFGMDMKAYLRSMIPHLES-----------------------------
-------GMKSSKSKD-VL-------------------------------------------------------------
----------------------SAAEVMQ---WS-QSLEKL-LANQ---TGQNVFGSFLKSEFSEENI--EFWLACEDYK
KT---ESDLLPCKAEEIYKAFVHSDAAKQIN----IDFRTRESTAKKIKA-PTPTC---FDEAQKVIYTLMEKDSYPRFL
KSDIYLNLLN---------DLQANSLK-----------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Mus_musculus_RGS1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------MRAAAISMP-------
----------------RLNKMPGMFFSAS---PKDSK-EHSHSLLD----------------------------------
--------------------------------------------------------------------------------
-----------------------DKKQKKRPKTFGMDVKTYLRSMIPHLES-----------------------------
-------GMKSAKSKD-IL-------------------------------------------------------------
----------------------SAEEVMQ---WS-QSLEKL-LANQ---TGQNVFGRFLKSEFSEENI--EFWLACEDYK
KT---ETDLLHNKAENIYKAFVHSDAVKQIN----IDFHTRESTAKKIKT-PTPTS---FDEAQKVIYSLMEKDSYPRFL
KSNIYLNLLN---------DLQANTLK-----------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Monodelphis_domestica_RGS1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------MRAAAISTP-------
----------------RLNKMPGIFFSSAN--TNELK-GSDHLLLD----------------------------------
--------------------------------------------------------------------------------
-----------------------DKTQKKKPKAFGTDLKAYLKSMLPHLES-----------------------------
-------GIKSSKSKD-IL-------------------------------------------------------------
----------------------SVTEVIQ---WS-QSLEKL-LTNQ---TGLAVFGNFLKSEFSEENI--EFWLACEDYK
RT---ESDHLHCKAEKIYKAFVQSDATKQIN----IDFHTRESTAKKIQV-PTPTS---FDEAQKVIYTLMERDSYPRFL
KSEVYLKLLS---------ELQGNSLK-----------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Xenopus_tropicalis_RGS1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------AADINVN-------
----------------ALYKMPGIFFSHAN----ALK--EVDNKPD----------------------------------
--------------------------------------------------------------------------------
-----------------------EVMAQKK-KNFAVDLKNYLKSMLPHLETM-----KSSS-------------------
-------STSSSDSEKNKL-------------------------------------------------------------
----------------------TPDEIIQ---WT-MSLEKL-LISE---DGQSVFREFLKSEFSEENI--EFWLACEDYK
ATN--DSEELRCKANVIYQEFIQPNANKQIN----IDFSTRNSVTKDLLE-PTITT---FNDAQKMIFILMERDSYPRFL
KSEIFLRLAE---------RHHGNNVRG----------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Homo_sapiens_RGS18
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------METTLLFFSQINMCESKEKTFFKLIHGSG----------------------------------
--------------------------------------------------------------------------------
-----------------------KEETSKEAKIRAKEKRNRLSLLVQKPE----FHEDTRS-------------------
-------SRSGHLAKETRV-------------------------------------------------------------
----------------------SPEEAVK---WG-ESFDKL-LSHR---DGLEAFTRFLKTEFSEENI--EFWIACEDFK
KSK--GPQQIHLKAKAIYEKFIQTDAPKEVN----LDFHTKEVITNSITQ-PTLHS---FDAAQSRVYQLMEQDSYTRFL
KSDIYLDLMEG--RPQRPTNLRRRSRSFTCNEFQDVQSDVAIWL------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Mus_musculus_RGS18
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------MDMSLVFFSQLNMCESKEKTFFKLMHGSG----------------------------------
--------------------------------------------------------------------------------
-----------------------KEETSIEAKIRAKEKRNRLSLLLQRPD----FHGETQA-------------------
-------SRSALLAKETRV-------------------------------------------------------------
----------------------SPEEAVK---WA-ESFDKL-LSHR---DGVDAFTRFLKTEFSEENI--EFWVACEDFK
KCK--EPQQIILKAKAIYEKFIQNDAPKEVN----IDFHTKEVIAKSIAQ-PTLHS---FDTAQSRVYQLMEHDSYKRFL
KSETYLHLIEG--RPQRPTNLRRRSRSFTYNDFQDVKSDVAIWL------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Gallus_gallus_RGS18
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------MENPLLLFPQLNISASKDKSYYKVMKPTV----------------------------------
--------------------------------------------------------------------------------
-----------------------KEEPNKASKPGAKQKRNRLSLLLQKSE----LHEAEHL-------------------
-------GKPTNLTKAPSV-------------------------------------------------------------
----------------------SPEEAMK---WG-ESFDKL-LSQK---DGLDAFTRFLKTEFSEENI--EFWIACEDYK
KSK--TTNELFPKAKTIYEMFIRKDAPKEVN----LDFKTKEVTSQNIEQ-PVITT---FDAAQNTVYRLMEQDSYPRFL
RSDLYLNLVKG--RNPGRPTLRRRSRSFTVNDFQGVRPDFTIWQ------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Anolis_carolinensis_RGS18
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------PDVIKK---WG-ESFYNL-ISQK---AGVDTFTQFLRSEFSEENI--EFWMACEDYK
KCK--DASQLSLKAQAIYETFIEKEAPKEVN----LDFNTKVCTSENMSH-PTLNT---FDAAQNKIYALMEQDSYPRFL
KSDLYLDMVHG--QPRGHSALRRRSRSFTFNEFKDVQPDFAIWM------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Danio_rerio_RGS18_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------MRSEDEQLAC------------------------------
--------------------------------------------------------------------------------
---------------------RMKETHL-----RSKDKKGRLSLLLARSG----SHENVSP-------------------
-------DKK-PQAKSNHI-------------------------------------------------------------
----------------------PPDVAMK---WS-DSFEDL-LSHS---DGVEVFTRFLRTEFSEENI--EFWLACEDFK
TTE--SSTKLQTKAKQIHAIFIDKEAPKEIN----IDHSTKAAIEKNILQ-PTNSC---FDAAQHKIYGLMKRDCYPRFL
ASDIYLTLTKR--SGP-PTMTRRRSRSFVFNERPEG---TAAWL------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Takifugu_rubripes_RGS18_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------METLLLLFPQFSFTAQKEEVYFRMLGPGATQAA------------------------------
--------------------------------------------------------------------------------
---------------------KMKEDSSSHGRQKDKERTSRLSLFLAKSG----SHENVSP-------------------
-------HKT-TNSTANNV-------------------------------------------------------------
----------------------SPELALR---WS-DSFEEL-LSHS---DGVEVFSQFLRKEFSKENI--EFWLACEEFK
TID--SRTKMLSKAKYIYTVFCETDSPKEIN----IDYNTRMAIQRSMAK-PTKGC---FEAAQQQVYNLMKKDSYPRFL
LSDTYLNLTRR--RGPGATMFRRRSRSCVFNERGEAAAEPSAW-------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Tetraodon_nigroviridis_RGS18_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------METLLLLFPQFSYTTQKQEAYCRMLAPGASRAL------------------------------
--------------------------------------------------------------------------------
---------------------KMKEDSS---GQKDKERKSRLSLFLTKSG----SHENVSP-------------------
-------HKK-KNAPANNV-------------------------------------------------------------
----------------------SPESALQ---WS-DSFEEL-LSHS---DGVEVFSQFLRKEFSEENI--EFWLACEEYK
TID--SETKLLSKAKYIYTVFCEPDSPKEIN----IDYNTRMAIQRGVAK-PTKGC---FEAAQLQVYNLMKKDSYPRFL
LSDTYLRLTGR--RGPRANMFRRRSRSCVFDERGEAAAERSAW-------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Gasterosteus_aculeatus_RGS18_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------MKDDSS---RQKDKERKSRLSLFLTKSG----SHENVSP-------------------
-------TKK-TNTT-TNI-------------------------------------------------------------
----------------------SPETALQ---WS-DSFEEL-LKHS---DGVESFSQFLRTEFSEENI--EFWLACEEYK
TID--SDTKLLSKAKCIYTVYIDSDAPKEIN----IDYNTKAAIQKVIAK-PTKSC---FEAAQLIVYSLMKKDSYPRFL
HSDIYLRLTRR--KGPGTNMFRRRSRSCVFNDRGEATTEPSAW-------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Oryzias_latipes_RGS18_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------METLLFLFPQFTYMAPKEEAYFKMLGAEDAQAA------------------------------
--------------------------------------------------------------------------------
---------------------KMKDDSS---RQNEKERKSRFSLFLTKSG----SHENISP-------------------
-------QKK-TNTTLSNI-------------------------------------------------------------
----------------------SPETALQ---WS-DSFEDL-LKHP---DGVEAFTQFLRTEFSEENI--EFWLVCEEYK
SID--SKSKLLSKAKYIYTVFIESEAPKEVN----IDYNTKMAIKANMSH-PTRST---FEAAQMKVYSLMKKDCYPRFL
HCDIYLRLTRR--KGPGATMFRRRSRSCVFNERGEP-TQPSAW-------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Homo_sapiens_RGS16
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------MCR-TLAA-----------------------------------
--------------------------------------------------------------------------------
--------------------------FPTTCLERAKEFKTRLGIFLHKSELGCD--TGSTG-------------------
-------KFEWGSKHSKEN-------------------------------------------------------------
--------------------RNFSEDVLGWR----ESFDLL-LSSK---NGVAAFHAFLKTEFSEENL--EFWLACEEFK
KIR--SATKLASRAHQIFEEFICSEAPKEV----NIDHETHELTRMNLQT-ATATC---FDAAQGKTRTLMEKDSYPRFL
KSPAYRDLAAQASAASATLS--SCSLDEPSHT------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Pan_troglodytes_RGS16
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------MCR-TLAA-----------------------------------
--------------------------------------------------------------------------------
--------------------------FPTTCLERAKEFKTRLGIFLHKSELGCD--TGSTG-------------------
-------KFEWGSKHSKEN-------------------------------------------------------------
--------------------RNFSEDVLGWR----ESFDLL-LSSK---NGVAAFHAFLKTEFSEENL--EFWLACEEFK
KIR--SATKLASRAHQIFEEFICSEAPKEV----NIDHETRELTRMNLQT-ATATC---FDAAQGKTRTLMEKDSYPRFL
KSPAYRDLAAQASAASATLS--SCSLAEPSHT------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Mus_musculus_RGS16
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------MCR-TLAT-----------------------------------
--------------------------------------------------------------------------------
--------------------------FPNTCLERAKEFKTRLGIFLHKSELSSD--TGGIS-------------------
-------KFEWASKHNKE--------------------------------------------------------------
--------------------RSFSEDVLGWR----ESFDLL-LNSK---NGVAAFHAFLKTEFSEENL--EFWLACEEFK
KIR--SATKLASRAHHIFDEYIRSEAPKEV----NIDHETRELTKTNLQA-ATTSC---FDVAQGKTRTLMEKDSYPRFL
KSPAYRDLAAQASATSTSAP--SGSPAEPSHT------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------
>Canis_familiaris_RGS16
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------MCR-TLAA-----------------------------------
--------------------------------------------------------------------------------
--------------------------FPTTCLERAKEFKTRLGIFLHKSELGSD--TGNVG-------------------
-------KFEWSSKHSKDG-------------------------------------------------------------
--------------------RNFSEDVLGWK----ESFDSL-LSSK---NGVAAFHAFLKTEFSEENL--EFWLACEEFK
KLR--SAAKLASRAHKIFEEFIRSEAPKEV----NIDHETRELTEKNLQA-ATATC---FDVAQGKIRTLMEKDSYPRFL
KSPAYRDLAAQASAASASQS--GCSPAEPLHT------------------------------------------------
-------------------------------------