>Homo_sapiens_GRHL3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------MSNEL
D-------FRSVRLLKNDPVNL--QKFSYTS--EDEAWKTYLENPLTAATKAMMRVNGDDDSVAALSFLYDYYMG-----
--------------------------------------------------PKEKRILSSSTGGRNDQGKRYYHGMEYETD
LTPLESPTHLMKFLTE--NVSGTPEYPDLL--------------------------------------------------
----------------------------KKNNLMSLEGALPTPGKAAPLPAGPSKLEAGSVD--------SYLLPTT---
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------DMYD
NGSLNSLFESIHGV--PPTQRWQPDSTFKDDPQESM-------LFPDILKTSPEPPCPEDYPSLK-------SDFEYTLG
SPKAIHIKSGESPMAYLNK---GQFYPVTLRTPAGGKGLALSS----NKVKSVVMVVFDNEKVPVEQLRFWKHWHSRQPT
AKQ------RVIDVADC------------------------KENFNTVEHIEEVAYNALSFVWNVNE--EAKVFIGVNCL
STDFSSQK--GVKGVPLNLQIDTYDCG-----L----------------------------------GTERLVHRAVCQI
KIFCD-KGAERKMRDDERKQFRRKVKCPDSSN--------------------------SGVKGCLLSGFR----------
-------------------------GNETTYLRPETD-------------LETPPVLFIPNVHFSSLQRSGG--------
------------------------------------------------------AAPSAGPSSSN---------------
---------------------------RLPLKRTCSPFTEEFEPLPSKQ-------------------------------
---------AKEGDLQR-------------------------VLLYVRRETEE---------------------------
--------------------------------------------------------------------------------
VFDALMLKTPDLK-----------------GLRNAISEKYGFPEENIYK---------------VYKKCKRGETS-LLHP
RLSRHPPPDCLECSHPVTQVRNMGFGDGFWRQR-------------DLDSN----PSPTTVNSLHFTVNSE---------
----------
>Gorilla_gorilla_GRHL3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------MSNEL
D-------FRSVRLLKNDPVNL--QKFSYTS--EDEAWKTYLENPLTAATKAMMRVNGDDDSVAALSFLYDYYMG-----
--------------------------------------------------PKEKRILSSSTGGRNDQGKRYYHGMEYETD
LTPLESPTHLMKFLTE--NVSGTPEYPDLL--------------------------------------------------
----------------------------KKNNLMSLEGALPTPGKAAPLPAGPSKLEAGSVD--------SYLLPTS---
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------DMYD
NGSLNSLFESIHGV--PPTQRWQPDSTFKDDPQESM-------LFPDILKTSPEPPCPEDYPSLK-------SDFEYTLG
SPKAIHIKSGESPMAYLNK---GQFYPVTLRTPAGGKGLALSS----NKVKSVVMVVFDNEKVPVEQLRFWKHWHSRQPT
AKQ------RVIDVADC------------------------KENFNTVEHIEEVAYNALSFVWNVNE--EAKVFIGVNCL
STDFSSQK--GVKGVPLNLQIDTYDCG-----L----------------------------------GTERLVHRAVCQI
KIFCD-KGAERKMRDDERKQFRRKVKCPDSSN--------------------------SGVKGCLLSGFR----------
-------------------------GNETTYLRPETD-------------LETPPVLFIPNVHFSSLQRSGG--------
------------------------------------------------------AAPSAGPSSSN---------------
---------------------------RLPLKRTCSPFTEEFEPLPSKQ-------------------------------
---------AKEDDLQR-------------------------VLLYVRRETEE---------------------------
--------------------------------------------------------------------------------
VFDALMLKTPDLK-----------------GLRNAISEKYGFPEENIYK---------------VYKKCKRGETS-LLHP
RLSHHPPPDCLECSHPVTQVRNMGFGDGFWRQR-------------DLDSN----PSPTTVNSLHFTVNSE---------
----------
>Mus_musculus_GRHL3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------MSNEL
D-------FRSVRLLKNDPVSF--QKFPYSN--EDEAWKTYLENPLTAATKAMMRVNGDEESVAALSFLYDYYM------
-------------------------------------------------GPKEKRILSSSTGGRNDQGKKFYHSMDYEPD
LAPLESPTHLMKFLTE--NVSGSPDYTDQL--------------------------------------------------
----------------------------KKNNLLGLEGVLPTPGKTNTVPPGPSKLEASSMD--------SYLLPAS---
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------DIYD
NGSLNSLFESIHGV--PPTQRWQPDSTFKDDPQESL-------LFPDILKTSPDPPCPEDYPGLK-------SDFEYTLG
SPKAIHIKAGESPMAYLNK---GQFYPVTLRTPAGGKGLALSS----SKVKSVVMVVFDNDKVPVEQLRFWRHWHSRQPT
AKQ------RVIDVADC------------------------KENFNTVQHIEEVAYNALSFVWNVNE--EAKVFIGVNCL
STDFSSQK--GVKGVPLNLQIDTYDCG-----A----------------------------------GTERLVHRAVCQI
KIFCD-KGAERKMRDDERKQFRRKVKCPDSSNN-------------------------AGIKGCLLSGFR----------
-------------------------GNETTYLRPETD-------------LETQPVLFIPNLHFSSLQRPGG--------
------------------------------------------------------VVPSAGHSSSD---------------
---------------------------RLPLKRTCSPFAEEFEPLPSKQ-------------------------------
---------AKEDDLQR-------------------------VLLYVRRETEE---------------------------
--------------------------------------------------------------------------------
VFDALMLKTPDLK-----------------GLRNAISEKYGLPEENICK---------------VYKKCKRGILVNMDNN
IIQHYSNHVAFLLDMG------------------------------ELDGK----IQIILKEL-----------------
----------
>Rattus_norvegicus_GRHL3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------MSNEL
D-------FRSVRLLKNDPVSF--QKFPYNN--EDEAWKTYLENPLTAATKAIMRVNGDDESVAALSFLYDYYM------
-------------------------------------------------GPKEKRILSSSTGGRNDQGKKYYHSMDYEPD
LAPLESPTHLMKFLTE--NVSGSPDYTDQL--------------------------------------------------
----------------------------KKNNLLGLEGALPTPGKTSTLPPGPSKLEAGSMD--------SYLLPTS---
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------DMYD
NSSLNSLFESIHGV--PPTH-----------------------------------------------------DFEYTLG
SPKAIHIKAGESPMAYLNK---GQFYPVTLRTPAGGKGLSLSS----SKVKSVVMIVFDNDKVPVEQLRFWRHWHSRQPT
AKQ------RVIDVADC------------------------KENFNTVQHIEEVAYNALSFVWNVNE--EAKVFIGVNCL
STDFSSQK--GVKGVPLNLQIDTYDCG-----A----------------------------------GTERL--------
-------GAERKMRDDERKQFRRKVKCPDSSNN--------------------------GIKGCLLSGFR----------
-------------------------GNETTYLRPEAD-------------LETQPVLFIPNLHFSSLQRPGG--------
------------------------------------------------------VVPSAGHSSSD---------------
---------------------------RLPLKRTCSPFAEEFEPLPSKQ-------------------------------
---------AKEDDLQR-------------------------VLLYVRRETEE---------------------------
--------------------------------------------------------------------------------
VFDALMLKTPDLK-----------------GLRNAISEKYGFPEENICK---------------VYKKCKRGILVNMDNN
IIQHYSNHVAFLLDMG------------------------------ELDGK----IQIILKEL-----------------
----------
>Bos_taurus_GRHL3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------------SF-------
S-------FRSVRLLKNDPVNF--QKFPYTN--EDEAWKTYLENPLTAATKAMMRVNGDDDSVAALSFLYDYYM------
-------------------------------------------------GPKEKRLLSSSTGGRNDQGKRYYHGMEYEMD
LTPLESPTHLMKFLTE--NVSGTPEYPDVL--------------------------------------------------
----------------------------KKNNLMSVEGAAPTPGKAALLPAGPSKLETGSVD--------SYLLPTS---
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------DVYD
NGSLSSLFESIHGV--PPTQRWQPDSTFKDDPQESL-------LFPDILKTSPEPPGPEDYPNPK-------SDFEYTLG
SPKAIHIKSGESPMAYLNK---GQFYPVTLRTPAGGKGLALSS----NKVKSVVMVVFDNEKGPVEQLRFWKHWHSRQPT
AKQ------RVIDVADC------------------------KENFNTVQHIEEVAYNALSFVWNVHE--EAKVFVGVNCL
STDFSSQK--GVKGVPLNLQIDTYDCG-----S----------------------------------GTERLVHRAVCQI
KIFCD-KGAERKMRDDERKQFRRKVKCPDSSN--------------------------SGIKGSLLAGFR----------
-------------------------GNETTYLRPEAD-------------LETPPVLFIPNVHFSSLQRPGG--------
------------------------------------------------------LILSK-KNNVD---------------
---------------------------ELALKRTCSPFTEEFEPLPSKQ-------------------------------
---------AKEDDLQR-------------------------VLLYVRRETEE---------------------------
--------------------------------------------------------------------------------
VFDALMLKTPDLK-----------------GLRSAISEKYGFPEENIYK---------------VYKKCKRGILVNMDNN
IIRHYSNHVAFLLDMG------------------------------ELDGK----IQIILKEL-----------------
----------
>Monodelphis_domestica_GRHL3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------MSNEL
D-------FRSVQVLKNDAVNF--QKFSCTN--EDEAWKTYLGNPLTAATKAMMRVNGDEDSVAALSFLYDYYMG-----
--------------------------------------------------PKEKRILSSSTGARSDLGKRYHHGMEYEVD
FPPLESPTHLMKFLTE--NVSGSQEYPDLT--------------------------------------------------
----------------------------KKNNLMNLEGTAST--KSGLLPPGPSKLEDSPADG-------SYLLPTG---
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------DMYD
S-SLSNLFETIHGP--PPQQRWQPDSTFKDDGQESL-------LFPDILKSPSEPQCPEDYPGTK-------SDFEYTLG
SPKAIHIKSGESPMAYLNK---GQFYPVTLRTPGGGRCLHLSS----NKVKSMIMVVFDNEKIPVEQLRFWKHWHSRQPT
AKQ------RVIDVADC------------------------KENFNTVQHIEEVAYNALSFVWNVNE--EAKVFIGVNCL
STDFSTQK--GVKGVPLNLQIDTYDCG-----T----------------------------------GTDRLVHRAVCQI
KIFCD-KGAERKMRDDERKQFRRKAKCPDSSN--------------------------NGLKGCPLSNFR----------
-------------------------GNETTYLRPETD-------------LESQPVLFIPNIHFSNLQRNGV--------
------------------------------------------------------AGSPTIHNGTN---------------
---------------------------RLPLKRTCSPFSDDFDLLPPKQ-------------------------------
---------AKEDDLQR-------------------------VLLYVRRETEE---------------------------
--------------------------------------------------------------------------------
VFDALMLKTPDLK-----------------GLRNAISEKYGFPEESIYK---------------VYKKCKRGILVNMDNN
IIQHYSNHVAFLLDMG------------------------------ELDGK----IQIILKEL-----------------
----------
>Gallus_gallus_GRHL3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------MRCCLDMRIHLKQKGEQKQQNSPH
S-------FRSVRLMKNDTMNF--QKFSYTN--EDEAWKTYLENPLTAATKAMMRVNGDDDSVAALSLLYDYYMV-----
--------------------------------------------------PKEKRILPSGMMGRNELGKRQYHGMEYDSD
ITSFDGSAHLMKLLSE--NTSMTQEYCEPQ--------------------------------------------------
----------------------------KKNGLS-LEG-IPTPHKPAMLPPGTSKLD-ATP-D-------TYMVPPG---
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------DLYD
NSALNSLFETNPVA--TPQQRWQPDSTFKEDPQESL-------LFSDILKPQPEPPCSESYPTDGV----K-SDFEYTLG
SPKAIHIKSGDSPMAYLNK---GQFYPITLRAAGDSKCLHLSS----NKVKSVVMIVFDNEKIPTEQLKFWKHWHSRQPT
AKQ------RVIDVADC------------------------KENFNTVQNIEELAYNALSFVWNIHE--EAKVFIGVNCL
STDFSSQK--GVKGVPLNLQIDTYDYG-----N----------------------------------GTNHLVHRAVCQI
KIFCD-KGAERKMRDDERKQFRRKGKCLDSNN--------------------------NGLKGCLLSGFR----------
-------------------------GNEITFLRPETD-------------LETQPVLFIPNLHFSNQQRCGT--------
------------------------------------------------------ALPPA-VPNSA---------------
--------------------------NRLPLKRSGTSFTDEFDPVPPKQ-------------------------------
---------TKEEDPQR-------------------------VLLYVRRESEE---------------------------
--------------------------------------------------------------------------------
VFDALMLKTPDLQ-----------------GLRMAISEKYGLPEESIYK---------------VYKKCKRGILVNMDNN
IIQHYSNHMAFLLDMV------------------------------EAEDK----IQVILKEL-----------------
----------
>Anolis_carolinensis_GRHL3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------IALLR
S-------FRSVRLLKNDGMGF--QKFSCMN--EDEAWKTYLENPLTAATKAMMRVNGDDESVAALSLLCDYYMI-----
--------------------------------------------------PKEKRYVPSGNTGRNDIGKRHCHVMDYEPD
ISSFENSAQLMKLLAE--NVSVSQEYTDLP--------------------------------------------------
----------------------------KKNGLV-LDG-LPAPHKPPALPPGPSKME-ANPAE-------SYMIPSG---
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------DVYD
NGSLHSLFDAIHVA--PPQQRWQPDSTFKEDPQESL-------IFNDILKTQPEVPCSEGYSLNDA----K-SDFEYTLG
SPKAIHIKSGESPMAYLNK---GQFYPVSLKTVGDTKGLHLSS----DKVKSVVMVVFDNEKIPMEQLKFWKHWHSRQPT
AKQ------RVIDVADC------------------------KENFNTVQHIEEVAYNALSFVWNVAE--EAKVFVGVNCL
STDFSSQK--GVKGVPLNLQIDTYDFG-----T----------------------------------GTNRLVHRAICQI
KIFCD-KGAERKMRDDERKQFRRKGKCLDANN--------------------------NSLKSCLVSGFR----------
-------------------------GNEITYLKPQAD-------------LETQPVLFIPNVHFSNLQRCAT--------
------------------------------------------------------VLPASGVPHDP---------------
--------------------------SSALLLLC--QFLLEISPGPPLI-------------------------------
---------SALLLHLP-------------------------VLLYVRRESEE---------------------------
--------------------------------------------------------------------------------
VFDALMLKTPDLK-----------------GLRNAISEKYGLPEESIYK---------------VYKKCKRGILVNMDNN
IIQHYSNHMAFLLDVV------------------------------EAEEK----FQVTLKEL-----------------
----------
>Xenopus_tropicalis_GRHL3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------MSNEL
D-------YRPVMLLQNDIN----LKYSSPN--DDEAWSKYLENPMTAATKAMMRANGDDDGVAALSLLYDYYR------
-------------------------------------------------VPKEKRIITQGSTGRCDQVKR--SCIEYDSD
ISTYDS-TQLMRFLND--NNSSTHEYSETH--------------------------------------------------
----------------------------KKNSYLSLDCLINP----SKLPLSSGKLDNNAHD--------DFMATSC---
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------DVYE
KNPLTTLFDPIHVP--PPQQRWQPDSTFKEDTPEPL-------IFNDILRSQAESTCSEDYIPGEA----N-RDFECTLE
SPKAIHIKSGESPMAYLNK---GQFYPVNLRTAETRKCVHLTS----NKVKSVVMVVFDNEKNPEEQLKRWKHWHSRQPT
AKQ------RVIDVADY------------------------KENCNTVENIEEVAYNALSFVWNINE--EAKIFIGINCL
STDFSSQK--GVKGVPLNLQIDTYDFE-----T----------------------------------GVKRLIHRAVCQI
KIFCD-KGAERKMRDEERKQFRRKGKSADQNN--------------------------KDIKASVLPGYR----------
-------------------------GSDFTYLRPVTD-------------METHPVLFIPNIHYSNLQRCGV--------
------------------------------------------------------VLQSAADNSD----------------
---------------------------RLSLKRSSQSFPESFEAPPSKQ-------------------------------
---------QTNEDPQR-------------------------VLLYVRRETEE---------------------------
--------------------------------------------------------------------------------
VFDALMLKTPDLK-----------------GLRNAISEKYELPEERICR---------------VYKKCKRGILVNMDNN
IIQHYSNHVAFLLDLT------------------------------DVDGK----IQVTLKEL-----------------
----------
>Homo_sapiens_TFCP2L1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------MLFWHT-------------
--------------------------------------------------------QPEHYNQHNSGS----------YL
R-----------DVLALP------IFKQEE--------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------PQLSPENEARLPPLQY-------------------------------------------------VLC
AATSPAVKLHEETLTYLNQG---QSYEIRLLENRKLGDFQDLNT---KYVKSIIRVVFHDRRLQYTEHQQLEGWRWSRPG
DRI------LDIDIPLS------------------------VGILDPR--ASPTQLNAVEFLWDPA--KRASAFIQVHCI
STEFTPRKHGGEKGVPFRVQIDTFKQNENGEYT-------------------------------------EHLHSASCQI
KVFKP-KGADRKQKTDREKMEKRTAQEK--------------------------EKYQPSYETTILTE------------
----------------------------CSPWPDVA-------------YQVNSAPS--PSYNGS-PNSFG-----LGEG
-----NASPTH--PVEALPVGSD------------------------------HLLPSASIQDAQQWLHRNRFSQFCRLF
ASFS----------------------GADLLKMSRDDLVQICGPADGIRLFN----------------------------
-------------AIKG-------------------RNVRPKMTIYVCQELEQNRVPLQQKRDGSG--------------
-----------------------------------------------------DSN----------------------LS
VYHAIFLEELTTL-----------------ELIEKIANLYSISPQHIHR---------------VYRQGPTGIHVVVSNE
MVQN-FQDESCFVLSTIK---------------------------AESNDG----YHIILKCGL----------------
----------
>Macaca_mulatta_TFCP2L1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------MLFWHT-------------
--------------------------------------------------------QPEHYNQHNSGS----------YL
R-----------DVLALP------IFKQEE--------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------PQLSPENEARLPPLQY-------------------------------------------------VLC
AATSPAVKLHEETLTYLNQG---QSYEIRLLENRKLGDFQDLNT---KYVKSIIRVVFHDRRLQYTEHQQLEGWRWSRPG
DRI------LDIDIPLS------------------------VGILDPR--ASPTQLNAVEFLWDPA--KRASAFIQVHCI
STEFTPRKHGGEKGVPFRVQIDTFKQNENGEYT-------------------------------------EHLHSASCQI
KVFKP-KGADRKQKTDREKMEKRTAQEK--------------------------EKYQPSYETTILTE------------
----------------------------CSPWPDVA-------------YQVNSAPS--PSYNGS-PNSFG-----LGEG
-----NTSPTH--PVEALPVGSD------------------------------HLLPSASIQDAQQWLHRNRFSQFCRLF
ASFS----------------------GADLLKMSRDDLVQICGPADGIRLFN----------------------------
-------------AIKG-------------------RNVRPKMTIYVCQELEQNRVPLQQKREGSG--------------
-----------------------------------------------------DSN----------------------LC
VYHAIFLEELTTL-----------------ELIEKIANLYSISPQHIHR---------------VYRQGPTGIHVVVSNE
MVQN-FQDESCFVLSTIK---------------------------AESNDG----YHIILKCGL----------------
----------
>Mus_musculus_TFCP2L1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------MLFWHT-------------
--------------------------------------------------------QPEHYNQHNSGS----------YL
R-----------DVLALP------IFKQEE--------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------PQLSPENGARLPPLQY-------------------------------------------------VLC
AATSPAVKLHEETLTYLNQG---QSYEIRLLENRKLGDFQDLNT---KYVKSIIRVVFHDRRLQYTEYQQLEGWRWSRPG
DRI------LDIDIPLS------------------------VGILDPR--ASPTQLNAVEFLWDPS--KRASAFIQVHCI
STEFTPRKHGGEKGVPFRVQIDTFKQNESGDYS-------------------------------------EHLHSASCQI
KVFKP-KGADRKQKTDREKMEKRTAQEK--------------------------EKYQPSYETTILTE------------
----------------------------CSPWPDVP-------------YQANNTPS--PSYNGS-PNSFG-----LREG
-----NSSPNH--PVEPLPLGSD------------------------------HLLPSASIQDAQQWLHRNRFSQFCWLF
ASFS----------------------GADLLKMSRDDLVQVCGPADGIRLFN----------------------------
-------------AIKG-------------------RNVRPKMTIYVCQELEQNQLPLPQKQDDSG--------------
-----------------------------------------------------DNS----------------------LC
VYHAIFLEELTTL-----------------ELTEKIASLYSIPPQHIHR---------------VYRQGPAGIHVVVSNE
MVQN-FQDESCFILSTLK---------------------------AESNDG----YHIILKCGL----------------
----------
>Canis_familiaris_TFCP2L1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------XYNQHSSGS----------YL
R-----------DVLALP------IFKQEE--------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------PQLSPENEARLPPLQY-------------------------------------------------VLC
AATSPAVKLHEETLTYLNQG---QSYEIRLLENRKLGDFQDLNT---KYVKSIIRVVFHDRRLQYTEHQQLEGWRWSRPG
DRI------LDIDIPLS------------------------VGILDPR--ASPTQLNAVEFLWDPS--KRASAFIQVHCI
STEFTPRKHGGEKGVPFRVQIDTFKQNENGEYT-------------------------------------EHLHSASCQI
KVFKP-KGADRKQKTDREKMEKRTAQEK--------------------------EKYQPSYETTILTE------------
----------------------------CSPWPDMA-------------YQVNSAPS--PSYNGS-PNSFG-----LGEG
-----NSSPTH--PVETLPLSND------------------------------HLLPSASIQDAQQWLHRNRFSQFCRLF
ASFS----------------------GADLLKMSRDDLVQICGPADGIRLFN----------------------------
-------------AIKG-------------------RNVRPKMTIYVCQELEQNRAPLQQKRDGG---------------
-----------------------------------------------------DSS----------------------LC
VYHAIFLEELTTL-----------------ELVEKIASLYSISPQHIHR---------------VYRQGPTGIHVVVSNE
MVQN-FQDESCFILSTLK---------------------------AESNDG----YHIILKCGL----------------
----------
>Felis_catus_TFCP2L1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------FITRDT-------------
--------------------------------------------------------QREEGDQDMSGG----------FV
QS----------DVLALP------IFKQEE--------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------PQLSPESEARLPPLQY-------------------------------------------------VLC
AATSPAVKLHEETLTYLNQG---QSYEIRLLENRKLGDFQDLNT---KYVKSIIRVVFHDRRLQYTEHQQLEGWRWSRPG
DRI------LDIDIPLS------------------------VGILDPR--ASPTQLNAVEFLWEPS--KRASAFIQVHCI
STEFTPRKHGGEKGVPFRVQIDTFKQNDNGEYT-------------------------------------EHLHSASCQI
KVFKP-KGADRKQKTDREKMEKRTAQEK--------------------------EKYQPSYETTILTE------------
----------------------------CSPWPDMA-------------YQVNSAPS--PSYNGS-PNSFG-----LGEG
-----NSSPTH--PVETLPLGND------------------------------HLLPSASIQDAQQWLHRNRFSQFCRLF
ASFS----------------------GADLLKMSRDDLVQICGPADGIRLFN----------------------------
-------------AIKG-------------------RNVRPKMTIYVCQELEQNRAPLQQKRDGGG--------------
-----------------------------------------------------DSS----------------------LC
VYHAIFLEELTTL-----------------ELVEKIANLYSISPQHIHR---------------VYRQGPTGIHVVVSNE
MVQN-FQDESCFILSTLK---------------------------AESNDG----YHVILKCGL----------------
----------
>Drosophila_melanogaster_TFCP2L1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------MALSFLSQNSGLLDLQSIFDPQYTHHQQQQQQLLHLSHHPQHHIQQHQNQQLQQQAEQIQQHQQERTLSTKFDL
NLFNELDQMEFNNLNRSQYQNNNNNNSISNNQNSNNNTNTTNGISENLNQIQNRHFISGYHHQHIGSDYEQVINFVDSPP
NSEESWT-------------DGQSKDSPGPQIIDVQTIYLNSGSRKRRMDWDSLDIGQSENSPTASQSGDLPSKVAHQ--
-------------------------------------------------------EKEKHKREKHSGRSSWSDDIGFDLN
AEFNSNSYLNNENFLSFSP--TLTTLKQEPQTDQIKPSPKVSLDNASASPSIAIAKLDEVQNSPSQAISGQDSANGSGSA
ANGKHDVNSGLACGCGSPQ-------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------GSPLANAEYELNEKGKPQQLSVLDPAKIEIGS------------------ANG-----ATHAEDHKFQYILA
AATSIATKNNEETLTYLNQ---GQSYEIKL---KKIGDLSLYRD---KILKSVIKICFHERRLQFMEREQMQQWQQSRPG
ERI------IEVDVPLS------------------------YGLCHVSQPLSSGSLNTVEIFWDPL--KEVGVYIKVNCI
STEFTPKKHGGEKGVPFRLQIETYIENTNSATASGSGGSNNSAIASGSGSSGSAAPASPERTPSAGSNGKQAVHAAACQI
KVFKL-KGADRKHKQDREKIQKRPQSEQ--------------------------EKFQPSYECTIMNDISLDLVMSATTT
GCYS---------------------PEYMKLWPNSPVHIP------KYDGMLPFAPSAASPATSSSPIAIN---SVTSTN
SPTLKLMDATNMVSPQHVPADMDDYS--------------------------QNIMPESTPSQVTQWLTNHRLTAYLSTF
AQFS----------------------GADIMRMSKEDLIQICGLADGIRMFN----------------------------
-------------ILRA-------------------KTIAPRLTLYASVDGCSYNAIYLLSNTAKEL-------------
----------------------------------------------QQKLFKMPGFY---------------------EF
MAKASAQENGAGG-----------------AATAAAAALFNNWGMHSKYSGSGSNIFNDANKSCVYISGPSGILVTITDE
VLNNEIKDGSLYALEVQA------------------------------GKVI---LKLINKQDNN---------------
----------
>Apis_mellifera_TFCP2L1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------MELQFIMDGSADALNGTIWFPNTPSPPYEQLSPVRQNRCDPIATQHAMGYHSAENSLRQDKYN
SPKDSPEDGVQIRSSSESPQHLSPSSDNSPNCQQSTLKRRAGEPLSQITELE-KKHAKRDGSVGSNGSGQG---------
---------------------------------------------WSTQVEELAEHLAADFDGSLSALA--------ASD
LATAVASYNMSEALLALPSL---TVFKQEAPSPENQQNSNLNHVSQRTINSAPTNNVNNSVEADSNNNGQTAASLHQ---
---LLYPSNEEYPPTSSSG-------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------NHVSSSQQGSELNEDCRFQY-------------------------------------------------VLA
AATSIATKVNEETLTYLNQ---GQSYEIKL---KKLGDLSAYRG---KILKSTIRICFHERRLQYTEREQMLAWQRARPG
ERL------LEVDVPLS------------------------YGMVDVC--QPSPSNNSVEFMWDPT--KEVGVYIKVNCI
STEFTPKKHGGEKGVPFRIQVETRLPGG------------------------------------------PRLHAASCQV
KVFKL-KGADRKHKQDRDKILRRPPHEQ--------------------------DKYQPSYDCTVLSDIPLDSLSSSNVI
TQ------------------------SGGSPYASTEAISPQSR----STISGNTSPVVAPLALSVSNPGIVPLV-PASDA
VKENVGTAPALPSPAAILPDQSCIETERSS--------------------CLVQLSPDASAAQTTTWLRASRFNAFESTF
ASFS----------------------ASDILRLSRDDLIQICGLADGIRLFN----------------------------
-------------ALHS-------------------KAPTPKLTLYFSLEDNSS--------------------------
--------------------------------------------------------------------------------
LWRVAYLDSLTSS-----------------ALINKLLNTLSLSHDRLHS---------------VLFLGPQGIHVLVTDE
LVAN-MKDESMYFVETIK---------------------------DNASER----YKLLLKPSSRS--------------
----------
>Homo_sapiens_GRHL1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------MTQEY
D------NKRPVLVLQNEALYP--QRRSYTS--EDEAWKSFLENPLTAATKAMMSINGDEDSAAALGLLYDYYKVP----
--------------------------------------------------RERRSSTA-KPEVEHPEPDHSKRNSIPIVT
EQPLISAG--ENRVQVLKNVPFNIVLPHGNQ-------------------------------------------------
-------------------------LGIDKRGHLTAPDTTVTVSIATMPTH-SIKTETQPHGFAVGIPPA-VYHPEP---
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------TERVVVFD
RNLNTDQFS--SGAQAPNAQRRTPDSTFSETFKEGVQEVF-FPSDLSLRMPG---MNSEDY-VFDS---VSGNNFEYTLE
ASKSLRQKPGDSTMTYLNK---GQFYPITLKEVSSSEGIHHPI----SKVRSVIMVVFAEDKSREDQLRHWKYWHSRQHT
AKQ------RCIDIADY------------------------KESFNTISNIEEIAYNAISFTWDIND--EAKVFISVNCL
STDFSSQK--GVKGLPLNIQVDTYSYN-----N----------------------------------RSNKPVHRAYCQI
KVFCD-KGAERKIRDEERKQSKRK---------------------------------VSDVKVPLLPSH-----------
------------------------KRMDITVFKPFID-------------LDTQPVLFIPDVHFANLQRGTHVLP-----
----------------------------------------------------IASEELE-GEGSV---------------
-----------------------------LKRGPYGTEDDFAVPPSTKL-------------------------------
---------ARIEEPKR-------------------------VLLYVRKESEE---------------------------
--------------------------------------------------------------------------------
VFDALMLKTPSLK-----------------GLMEAISDKYDVPHDKIGK---------------IFKKCKKGILVNMDDN
IVKHYSNEDTFQLQIE------------------------------EAGGS----YKLTLTEI-----------------
----------
>Callithrix_jacchus_GRHL1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------MTQEY
D------NKRPVLVLQNEALYP--QRRSYTS--EDEAWKSFLENPLTAATKAMMSINGDEDSAAALGLLYDYYKVP----
--------------------------------------------------RERRSSTA-KPEVEHPEPDHSKRNSIPIVT
EQPLISAG--ENRVQVLKNVPFNIVLPHGNQ-------------------------------------------------
-------------------------LGIDKRGHLTAPDTTVTVSIATMPTH-SIKTETQPHGFAVGIPPA-VYHPEP---
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------TERVVVFD
RNLNTDQFS--SGAQAPNAQRRTPDSTFSETFKEGIQEVF-FPSDLSLRMPG---MNSEDY-VFDS---VSGNNFEYTLE
ASKSLRQKPGDSTMTYLNK---GQFYPITLKEVSSNEGVHHPI----SKVRSVIMVVFAEDKSREDQLRHWKYWHSRQHT
AKQ------RCIDIADY------------------------KESFNTISNIEEIAYNAISFTWDIND--EAKVFISVNCL
STDFSSQK--GVKGLPLNIQIDTYSYN-----N----------------------------------RSNKPVHRAYCQI
KVFCD-KGAERKIRDEERKQSKRK---------------------------------VSDVKVPLLPSH-----------
------------------------KRMDITVFKPFLD-------------LDTQPVLFIPDVHFANLQRGTHVLP-----
----------------------------------------------------IASEELE-GEGSA---------------
-----------------------------LKRGPYGTEDDFSVPPSTKL-------------------------------
---------SRIEEPKR-------------------------VLLYVRKESEE---------------------------
--------------------------------------------------------------------------------
VFDALMLKTPSLK-----------------GLMEAISDKYDVPHDKIGK---------------IFKKCKKGILVNMDDN
IVKHYSNEDTFQLQIE------------------------------EAGGS----YKLTLTEI-----------------
----------
>Mus_musculus_GRHL1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------MTQEY
D------NKRPVLVLQNEALYP--QRRSYTS--EDEAWKSFLENPLTAATKAMMSINGDEDSAAALGLLYDYYKVP----
--------------------------------------------------RERRSSAV-KPEGEHPEPEHSKRNSIPNVT
EQPLISAG--ENRVQVLKNVPFNIVLPHSNQ-------------------------------------------------
-------------------------LGIDKRGHLTAPDTTVTVSIATMPTH-SIKTEIQPHGFAVGIPPA-VYHSEP---
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------TERVVVFD
RSLSTDQFS--SGTQPPNAQRRTPDSTFSETFKEGVQEVF-FPSELSLRMPG---MNSEDY-VFDN---VSGNNFEYTLE
ASKSLRQKQGDSTMTYLNK---GQFYPVTLKEGSSNEGIHHPI----SKVRSVIMVVFAEDKSREDQLRHWKYWHSRQHT
AKQ------RCIDIADY------------------------KESFNTISNIEEIAYNAISFTWDIND--EAKVFISVNCL
STDFSSQK--GVKGLPLNIQIDTYSYN-----N----------------------------------RSNKPVHRAYCQI
KVFCD-KGAERKIRDEERKQSKRK---------------------------------VSDVKVQLLPSH-----------
------------------------KRTDITVFKPFLD-------------LDTQPVLFIPDVHFTNLQRGSHVLS-----
----------------------------------------------------LPSEELE-GEGSV---------------
-----------------------------LKRGPFGTEDDFGVPPPAKL-------------------------------
---------TRTEEPKR-------------------------VLLYVRKESEE---------------------------
--------------------------------------------------------------------------------
VFDALMLKTPSLK-----------------GLMEAISDKYDVPHDKIGK---------------IFKKCKKGILVNMDDN
IVKHYSNEDTFQLQIE------------------------------EAGGS----YKLTLTEI-----------------
----------
>Rattus_norvegicus_GRHL1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------NSIPNVT
EQPLISAG--ENRVQVLKNVPFNIVLPHSNQ-------------------------------------------------
-------------------------LGIDKRGHLTAPDTTVTVSIATMPTH-SIKTEIQPHGFTVGIPPA-VYHSEP---
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------TERVVVFD
RSLSTDQFS--SGPQPPNAQRRTPDSTFSETFKEGVQEVF-FPSELSLRMPG---MTSEDY-VFDS---VSGNNFEYTLE
ASKSLRQKQGDSTMTYLNK---GQFYPVTLKEVSSNEGIHHPI----SKVRSVIMVVFAEDKSREDQLRHWKYWHSRQHT
AKQ------RCIDIGEW------------------------PRSPPTSRRLQCPASQVLLLLAIINF--LLKVFISVNCL
STDFSSQK--GVKGLPLNIQIDTYSYN-----N----------------------------------RSNKPVHRAYCQI
KVFCD-KGAERKIRDEERKQSKRK---------------------------------VSDVKVQLLPSH-----------
------------------------KRTDITVFKPFLD-------------LDTQPVLFIPDVHFTNLQRGSHVLS-----
----------------------------------------------------LPTEELE-GDGSV---------------
-----------------------------LKRGPFGTEDDFGVPPPAKL-------------------------------
---------ARTEEPKR-------------------------VLLYVRKESEE---------------------------
--------------------------------------------------------------------------------
VFDALMLKTPSLK-----------------GLMEAISDKYDVPHDKIGK---------------IFKKCKKGILVNMDDN
IVKHYSNEDTFQLQIE------------------------------EAGGS----YKLTLTEI-----------------
----------
>Bos_taurus_GRHL1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------MTQEY
D------NKRPVLVLQNEALYS--QRRSYTS--EDEAWKSFLENPLTAATKAMMSINGDEDSAAALGLLYDYYKVP----
--------------------------------------------------RERRSSAA-KADVEHAEPDHSKRN-VPNVT
EQPLISAG--ENRVQVLKNVPFNIVLPHGNQ-------------------------------------------------
-------------------------LGIDKRGHPTAPDTTVTVSISAMPTH-AIKTESQPHGFTVGIPPA-VYHPEP---
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------TERVVVFD
RNLNADQFG--SGAQPPNAQRRTPDSTFSETFKEGVQEVF-FPSDLSLRMPG---MNSEDY-VFDS---VSGNNFEYTLE
ASKSLRQKPGDSTMTYLNK---GQFYPVTLKEVSGSEAVHHPI----GKVRSVIMVVFAEDKSREDQLRHWKYWHSRQHT
AKQ------RCIDIADY------------------------KESFNTISNIEEIAYNAISFTWDIND--EAKVFISVNCL
STDFSSQK--GVKGLPLNIQIDTYSYN-----N----------------------------------RSNKPVHRAYCQI
KVFCD-KGAERKIRDEERKQSKRKGKCT--------------------DPSSQLN-AFSDVKVPLLPSH-----------
------------------------KRMDITVFKPFID-------------LDTQPVLFIPDVHFASLQRGAHVLP-----
----------------------------------------------------IASEELE-GEGSS---------------
-----------------------------LKRGPYSAEDDFVIPPPAKL-------------------------------
---------TRVEEPKR-------------------------VLLYVRKESEE---------------------------
--------------------------------------------------------------------------------
VFDALMLKTPSLK-----------------GLMEAISDKYDVPQEKIGK---------------IFKKCKKGILVNMDDN
IVKHYSNEDTFQLQME------------------------------ESGGS----FKLTLTEI-----------------
----------
>Xenopus_tropicalis_GRHL1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------MTQDY
D------NKRPVLVLQNDGLYQ--QRRSYTS--EDEAWKSFLENPLTAATKAMMSINGDEDSAAALGLLYDYYKVP----
--------------------------------------------------RERRPSAA-KQEHDHADQEHNKRNGLPQIN
EQALLS----ENRVQVLKTVPFNIVVPLANQ-------------------------------------------------
-------------------------V--DKRGHLTTPDTTAAVSITSLPAH-PIKTESQSHCFSVGLQSV--FHTEP---
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------TERIVTFD
RTVPSDHFT--SNSQPPNSQRRTPDSTFSETYKEDVPEVF-FPPDLSLRMGS---MNSEDY-VFDS---VAGNNFEYTLE
ASKSLRPKPGDSTMTYLNK---GQFYPITLKEIGGNKGIHHPI----SKVRSVIMVVFADDKSREDQLRHWKYWHSRQHT
AKQ------RCIDIADY------------------------KESFNTISNIEEIAYNAISFTWDLND--EGKVFISVNCL
STDFSSQK--GVKGLPLNLQIDTYSYN-----N----------------------------------RSNKPVHRAYCQI
KVFCD-KGAERKIRDEERKQSKRK---------------------------------VQDVKVGLPPSH-----------
------------------------KRTDITVFKPMMD-------------LDTQPVLFIPDVHFANLQRTTHVLP-----
----------------------------------------------------IAPEDME-GELSSP--------------
----------------------------GMKRVPFSPEEDFTAPP-AKL-------------------------------
---------PRVDEPKR-------------------------VLLYVRRETEE---------------------------
--------------------------------------------------------------------------------
VFDALMLKTPTLK-----------------GLMEAVSDKYEVPIEKIGK---------------IFKKCKKGILVNMDDN
IIKHYSNEDTFQLQIE------------------------------ESGGS----YKLTLTEI-----------------
----------
>Danio_rerio_GRHL1_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------MSQEH
E------NKRAVLVLPNDPAYN--QRRPYTS--EDEAWKSFLENPLTAATKAMMSINGDEDSAAALGLLYDYYKVP----
--------------------------------------------------RDKRTISQQKTDVLGSDVDPNKRNMLTP-L
QETSMQLG--DNRIQVLKGVPLNIVLPG-NQ-------------------------------------------------
-------------------------HVQDKRGLFPSPDTTVTVSIAPVASN-SVKTEGPSHGFSVTVPNP--HCAEP---
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------DSHTVVFD
RQLPHN--QFSPNTQP----RTP-DSTFPE-----NPDVFSFPGDLQLRMGP---ITQDDYGTFDT---VSGNNFEYILE
ASKSLRQKSGDGTMTYLNK---GQFYPITLRETDNGKLLQGPI----CKVRSVVMVVFGEEKSRDDQLKHWKYWHSRQHT
AKQ------RCIDIADY------------------------KESFNTISNIEEISYNAISFTWDISE--EAKIFISVNCL
STDFSSQK--GVKGLPLNIQIDTYSYN-----N----------------------------------RSNKPIHRAYCQI
KVFCD-KGAERKIRDEERKQSRRKGKCP--------------------DVNPPLGNFGADVKVPLLH-------------
------------------------KRTDMTVFRTLTD-------------FETQPVLFIPDIHFSTFQRH----------
------------------------------------------------------AFTAEDSEEG-S--------------
----------------------------AMKRLPY-TEEEFGSPP-NKL-------------------------------
---------ARMDEPKR-------------------------VLLYVRRETEE---------------------------
--------------------------------------------------------------------------------
VFDALMLKTPTLK-----------------GLVEAISEKYEVSLEKIGK---------------VYKKCKKGILVNMDDN
IIKHYSNEDTFQIQME------------------------------EMGGM----IKLTLTEIE----------------
----------
>Takifugu_rubripes_GRHL1_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------MSQEH
D------NKRAVLVLQNEPGYGG-QRRSFTT--EDEAWKSFLENPLTAATKAMMSINGDEDSAAALGLLYDYYKVP----
--------------------------------------------------REKRTIPQNKPEALICDVDPNKRHQLQAGH
SITSLHDVGMENKIQVVKG-PFNIL-----Q-------------------------------------------------
-------------------------LAQDKRSQFSSPDTTVTVSIATVPNYPPIKTEVPSHSFSVTMPN---NCAET---
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------DGHAGVFE
RQLAHNGVQFSPSTQS----CTPPDSTFPESFKDSSQEVFSFPGELQLRMSS---IASEEYPQFDA---APGNNFEYTLE
ASKSLRQKTGDGTMTYLNK---GQFYPITLREIDN-KGIQQPI----TKVRSVVMVVFGEEKCRDDQLKHWKYWHSRQHT
AKQ------RCLDIADY------------------------KESFNTIGNIEEISYNAISFTWDTSD--EAKIFISVNCL
STDFSSQK--GVKGLPLNLQIDTYSYN-----N----------------------------------RSNKPIHRAYCQI
KVFCD-KGAERKIRDEERKQSRRK---------------------------------VADVKVPILQ-------------
------------------------KRNDVTIFKMMTD-------------FETQPILFIPDIHFSTFQRHGQYTL-----
----------------------------------------------------KAASETEEGEESSS--------------
----------------------------GMKRLPF-SDDEFASPP-NKM-------------------------------
---------AREEEPKK-------------------------VLLYVRKETEE---------------------------
--------------------------------------------------------------------------------
VFDAVMLKDPSLK-----------------GLVEAISEKYELPLEKIGK---------------VYKKCKKGILVHMDDN
IIRHYSNEDTFQITME------------------------------ELGGM----YKLTLTEI-----------------
----------
>Tetraodon_nigroviridis_GRHL1_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------MSQEH
D------NKRAVLVLQNEPGYGG-QRRSFTT--EDEAWKSFLENPLTAATKAMMSINGDEDSAAALGLLYDYYKVP----
--------------------------------------------------REKRTIPQNKPEALICDVDPNKRHQIQAGH
SIVPVHDAGVENKIQVVKG-PFNIL-----Q-------------------------------------------------
-------------------------LAQDKRGQFSSPDTTVTVSIAAVPNYQPIKTEGPSHSFSVSIPN---SCAET---
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------DGHVGVFD
RQLAHNGVPFSPGAQS----RTPPDSTFPESFKDGSQEVFSFPGDLQLRMSS---IASEEYPPFDA---VPGNNFEYTLE
ASKSLRQKTGDGTMTYLNK---GQFYPITLREIDN-KTVQQPI----TKVRSVVMVVFGEEKCRDDQLKHWKYWHSRQHT
AKQ------RCLDIADY------------------------KESFNTIGNIEEISYNAISFTWDTND--EAKIFISVNCL
STDFSSQK--GVKGLPLNLQIDTYSYN-----N----------------------------------RSNKPIHRAYCQI
KVFCD-KGAERKIRDEERKQSRRK---------------------------------VVDVKVPILQ-------------
------------------------KRNDVTVFKMMTD-------------FETQPILFIPDIHFSTFQRH----------
----------------------------------------------------AVPVSAQSSAHCSS--------------
----------------------------GIKRLPF-SDDEFASPP-SKM-------------------------------
---------AREEEPKKAT-----------------------VLLYVRKEAEE---------------------------
--------------------------------------------------------------------------------
VFDAVMLKNPTLK-----------------GLVEAISEKYELPLEKMGK---------------VYKKCKKGILVHMDDN
IIKHYSNEDTFQITVE------------------------------ELGGM----YKLTLTEI-----------------
----------
>Gasterosteus_aculeatus_GRHL1_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------MSQEH
D------NKRAVLVLQNEPGYAG-QRRSFTT--EDEAWKSFLENPLTAATKAMMSINGDEDSAAALGLLYDYYKVP----
--------------------------------------------------RDKRTITQSKPEALVCDVDPNKRHQIQLGH
PIP-LQEGGLENRIQVLKG-PFNIL-----Q-------------------------------------------------
-------------------------LAQDKRAQFASPDTTVTVSIAAVPNYTTVKTEGPAHGFSVTVPN---NCAET---
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------AGHVGVYD
RQLAHNVVQFSPGTHT----RTPPDSTFSESYKDGSQEVYSFPGDIQLRMA----MSPEDYTPFNT---VLGNNFEYTLE
ASKSLRQKSGDGTMTYLNK---GQFYPITLREADH-KAMQQPI----TKVRSVVMVVFGEEKCRDDQLKHWKYWHSRQHT
AKQ------RCLDIADY------------------------KESFNTIGNIEEISYNAISFTWDTNE--EAKIFISVNCL
STDFSSQK--GVKGLPLNLQIDTYSYN-----N----------------------------------RSNKPIHRAYSHI
KVFCD-KGAERKIRDEERKQTRRK---------------------------------VADAKVPLLQ-------------
------------------------KRNDVTFFKTMSD-------------HETQPVLFIPDIHFSTFQRQFP--------
----------------------------------------------------MQPFPTEDVEES-S--------------
----------------------------GMKRLPF-SDEEFGSPP-NKM-------------------------------
---------ARGGEPKK-------------------------VLLYVRKEAEE---------------------------
--------------------------------------------------------------------------------
VFDALMLKNPTLK-----------------GLVEAISEKYELPLDKVGK---------------VYKKCKKGILVHMDDN
IIKHYSNEDTFQITME------------------------------EMGGM----YKLTLTEI-----------------
----------
>Oryzias_latipes_GRHL1_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------MSQEH
DNF--IPSKRAVVVLQNKQGYGN-QRRSFTT--EDEAWKSFLENPLTAATKAMMSINGDEDSAAALGFLYDYYEVP----
--------------------------------------------------RDKRTIHQPKTELLASDVDPNKRQGKSS--
LEICLQEANMDNRVQVLKT-PINIL-----Q-------------------------------------------------
-------------------------LTSDKRTHFPSPDTTVTVSIATVPNYQSVKTEGPSHGFSVTVPN---NCND----
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------AGVFD
RQLNQNAIQFSPSTQS----RTPPDSTFPESFKDGSQE--------EVFKHP---PPQVKMFAFDQ---NCSNNFEYSLE
ASKSLRQKTGDGTMTYLNK---GQFYPITLREVDN-KGIQQPI----TKVRSVVMVVFGEEKCREDQLKHWKYWHSRQHT
AKQ------RCLDIADY------------------------KESFNTIDNIEEISYNAISFTWDTNE--EAKIFISVNCL
STDFSSQK--GVKGLPLNLQIDTYSYN-----N----------------------------------RSNKPIHRAYCQI
KVFCD-KGAERKIRDEERKQSRRKGKVP--------------------DLSCNPP--FADMKVPILQ-------------
------------------------KRNDVTIFKMMND-------------LETQPVLFIPDIHFSALQRHPMKS------
----------------------------------------------------YNPFSAEEGEDR-Y--------------
----------------------------VSHLLYI-SDDEFAPPP-NKM-------------------------------
---------PRVDEPKK-------------------------VLLYVRKETEE---------------------------
--------------------------------------------------------------------------------
VFDALMLKNPTLK-----------------GLMEAISEKYELPLDKIGK---------------VYKKCKKGILVHMDDN
IIKHYSNEDTFQITME------------------------------DQGGT----YKLTLTEI-----------------
----------
>Branchiostoma_floridae_GRHL1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----MTQEVDNSKRSVVVLQNEALYRNTYSSRDEDEAWRSYLENPLTAATTAMLNINGDEDSAAALGLLYDYYKV-----
--------------------------------------------------PKEKRMNAN--------YVTRTPMGPPETD
QPSRDLTMLRNVPLADSITSSGFDGHHAHSS-------------------------------------------------
-------------------------PVTTQPPATSPLTVRADHH--------IHIHKPDHSPMIVAKPDEMDRTPDSAFS
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------------EATFKDHQQ
EHDVLGDDMSAFQVFNYNISQVSLAAAHVQRRQQPELLQQVITETQIMPPP----------------EPINGVAFEYILE
APKSLRQKPGEASMSYVNK---GQFYAVTLTEAGS-SPWRHHS----TKVRSVIQVVFGDGRSEEEQLKHWRYWHARQHT
ARQ------RIIDMADY------------------------KESTNVIENIDEIAHNAIAFSWDVRE--TGKVFISVNCL
STDFSSQK--GIK-------IDTYTDY-----F----------------------------------KGATPVHRAYVQI
KVFCD-KGAERKIRDEVRKISKKKQSEEIKS------------------------------------QIPSH--------
------------------------KRNELAYFKPMAD-------------LKTPPVLFVPDFIPAARAP-PQITQ-----
----------------------------------------------------PVTFGLTPPFDR----------------
----------------------------GMKRSFSEDSAYSPESSPTP--------------------------------
---------AAKVANKS-------------------------VLLYVRKEEDD---------------------------
--------------------------------------------------------------------------------
VYDALMLREPSVQ-----------------GLLSAVEEKYKVPNDKVSK---------------VFKKSKKGILVNIDDN
IIEHYCNEDTFIIELQ------------------------------EETDGNIRVILTEVQDTP----------------
----------
>Caenorhabditis_elegans_GRHL1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------MSFQLDQSTSVIKTAPPGRLEFKNEPIDIASSNIQDLAKMQTLDGYYQQTS---
------LQLPQSQ-------------------------------------QYHRMYENVYNNQQILYAQTQNFQYPSTLL
TNGSLAQTEWRGQQMDTSAYSNTGYSRSS---------------------------------------------------
------------------------TSQQPQYTQQVTENERIVYKPVDMPSPVDSGIGGDISILNPK--------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------EEFFTSADGGSMLERSSERTLSHRDSP---------------------LVIPKLYN-----NLGFQYVLE
APISTSVRRDDDRMTYVNK---GQFYTVSLEYTPDLNKC-LKS----QTVKSQLMVVFREDKTYEEEIKTWQSWHARQHV
SKQ------RILEIDSK------------------------NSSGMIG-QIEEIGNNAVQFYWNPSDPSGVRISIAVQCL
STDFSTQK--GVKGLPLHVQIDTYDGE----------------------------------------NDKVPFHRGYCQI
KVFCD-KGAERKLRDEDKRAQKRKVQEYTAGALPG-----------------------GRKKSDGEYHD-----------
-------------------------QCERSEFYHMRE-------------LDKPAALFIAPEEF----------------
--------------------------------------------------------------------------------
-----------------------EPRYVDSTSLSFDMSEIEPIPTKRPRTS-----------------------------
----------------------------------------ERIMLYVRKRDEQ---------------------------
--------------------------------------------------------------------------------
IYQPLHVVPASLS-----------------GLALAIANKFGADPDKMSG---------------VYKRCAKGITVKVDDE
MLRLYCNEDTFIIDVEH-----------------------------ATDGS----TAATLIEVAPTNPNSYSNS------
----------
>Homo_sapiens_GRHL2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------MSQES
-----DNNKRLVALVPMPSDPPFNTRRAYTS--EDEAWKSYLENPLTAATKAMMSINGDEDSAAALGLLYDYYKV-----
--------------------------------------------------PRDKRLLSVSKASDSQEDQEK-RNCLGTSE
AQSNLSG--GENRVQVLKTVPVNLSLNQDHL-------------------------------------------------
-------------------------ENSKREQYSISFPESSAIIP--VSGITVVKAEDFTPVFMA--PPVHYPRGDG---
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------------EEQRVVIFE
QTQYDVPSLATHSAYLKDDQRSTPDSTYSESFKDA--------ATEKFRSAS---VGAEEY-MYD---QTSSGTFQYTLE
ATKSLRQKQGEGPMTYLNK---GQFYAITLSETGDNKCFRHPI----SKVRSVVMVVFSEDKNRDEQLKYWKYWHSRQHT
AKQ------RVLDIADY------------------------KESFNTIGNIEEIAYNAVSFTWDVNE--EAKIFITVNCL
STDFSSQK--GVKGLPLMIQIDTYSYN-----N----------------------------------RSNKPIHRAYCQI
KVFCD-KGAERKIRDEERKQNRKKGKG---------------------QASQTQCNSSSDGKLAAIPLQ-----------
------------------------KKSDITYFKTMPD-------------LHSQPVLFIPDVHFANLQRTGQVY------
----------------------------------------------------YNTDDER--EGGSV--------------
----------------------------LVKRM-FRPMEEEFGPVPSKQ-------------------------------
---------MKEEGTKR-------------------------VLLYVRKETDD---------------------------
--------------------------------------------------------------------------------
VFDALMLKSPTVK-----------------GLMEAISEKYGLPVEKIAK---------------LYKKSKKGILVNMDDN
IIEHYSNEDTFILNME------------------------------SMVEG----FKVTLMEI-----------------
----------
>Gorilla_gorilla_GRHL2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------MSQES
-----DNNKRLVALVPMPSDPPFNTRRAYTS--EDEAWKSYLENPLTAATKAMMSINGDEDSAAALGLLYDYYKV-----
--------------------------------------------------PRDKRLLSVSKASDSQEDQEK-RNCLGTSE
AQSNLSG--GENRVQVLKTVPVNLSLNQDHL-------------------------------------------------
-------------------------ENSKREQYSISFPESSAIIP--VSGITVVKAEDFTPVFMA--PPVHYPRGDG---
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------------EEQRVVIFE
QTQYDVPSLATHSAYLKDDQRSTPDSTYSESFKDA--------TTEKFRSAS---VGAEEY-MYD---QTSSGTFQYTLE
ATKSLRQKQGEGPMTYLNK---GQFYAITLSETGDNKCFRHPI----SKVRSVVMVVFSEDKNRDEQLKYWKYWHSRQHT
AKQ------RVLDIADY------------------------KESFNTIGNIEEIAYNAVSFTWDVNE--EAKIFITVNCL
STDFSSQK--GVKGLPLMIQIDTYSYN-----N----------------------------------RSNKPIHRAYCQI
KVFCD-KGAERKIRDEERKQNRKKGKG---------------------QASQTQCNSSSDGKLAAIPLQ-----------
------------------------KKSDITYFKTMPD-------------LHSQPVLFIPDVHFANLQRTGQVY------
----------------------------------------------------YNTDDER--EGGSV--------------
----------------------------LVKRM-FRPMEEEFGPVPSKQ-------------------------------
---------MKEEGTKR-------------------------VLLYVRKETDD---------------------------
--------------------------------------------------------------------------------
VFDALMLKSPTVK-----------------GLMEAISEKYGLPVEKIAK---------------LYKKSKKGILVNMDDN
IIEHYSNEDTFILNME------------------------------SMVEG----FKVTLMEI-----------------
----------
>Mus_musculus_GRHL2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------MSQES
-----DNNKRLVALVPMPSDPPFNTRRAYTS--EDEAWKSYLENPLTAATKAMMSINGDEDSAAALGLLYDYYKV-----
--------------------------------------------------PRDKRLLSVSKASDSQEDQDK-RNCLGTSE
AQINLSG--GENRVQVLKTVPVNLCLSQDHM-------------------------------------------------
-------------------------ENSKREQYSVSITESSAVIP--VSGITVVKAEDFTPVFMA--PPVHYPRADS---
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------------EEQRVVIFE
QTQYDLPSIASHSSYLKDDQRSTPDSTYSESFKDG--------ASEKFRSTS---VGADEY-TYD---QTGSGTFQYTLE
ATKSLRQKQGEGPMTYLNK---GQFYAITLSETGDNKCFRHPI----SKVRSVVMVVFSEDKNRDEQLKYWKYWHSRQHT
AKQ------RVLDIADY------------------------KESFNTIGNIEEIAYNAVSFTWDVNE--EAKIFITVNCL
STDFSSQK--GVKGLPLMIQIDTYSYN-----N----------------------------------RSNKPIHRAYCQI
KVFCD-KGAERKIRDEERKQNRKKGKG---------------------QASQAQCNNSSDGKMAAIPLQ-----------
------------------------KKSDITYFKTMPD-------------LHSQPVLFIPDVHFANLQRTGQVY------
----------------------------------------------------YNTDDER--EGSSV--------------
----------------------------LVKRM-FRPMEEEFGPTPSKQ-------------------------------
---------IKEENVKR-------------------------VLLYVRKENDD---------------------------
--------------------------------------------------------------------------------
VFDALMLKSPTVK-----------------GLMEALSEKYGLPVEKITK---------------LYKKSKKGILVNMDDN
IIEHYSNEDTFILNME------------------------------SMVEG----FKITLMEI-----------------
----------
>Felis_catus_GRHL2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------LNKEQ
-----SSTKRLVALVPMPSDPPFNTRRAYTS--EDEAWKSYLENPLTAATKAMMSINGDEDSAAALGLLYDYYKV-----
--------------------------------------------------PRDKRLLSVSKASDSQEEPDK-RNCLGTTE
AQNNLTG--GENRVQVLKTVPVNLSLNQDHL-------------------------------------------------
-------------------------ENSKREQYSTNISESPAIIP--VSGITVVKAEDFTPVFMA--PPVHCPRGDG---
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------------EEQRVLIFE
QTQYGVPSMASHSTYLKDDQRSTPDSTYSESFKDG-