>Homo_sapiens_FAM110D
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------MLLAPPSTPSRGRTPS------
------------------------------------------------------------------------------AV
ERL-----------------------------------------------------------------------------
-------------------------------------------EADKAKYVKTHQVIARRQEPALRG-------------
-------------------------------------------------------------SP---GPLTPHPCNELGP-
--------------------------------------------------------------------------------
-----------------------PASPRTPRPVRRGSGRRLPRP------------------------------------
-----------------DSLIFYRQKRDCKASVNKE--------------------------------------------
-------------------------------NAKGQG----------------------------------LVRRLFLGA
PRDAAPSSP-----------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------ASTERPAASGG----------WAAPQDAP----
--------------------------------------------------------------EAAGKRALCPTCS-----
--------------------------------------------------------------------------------
--LPLSEKERFFNYCGLERALVEVLG-----------------------------------AERFSPQSWGADASPQA--
GTSPP-PGSGDASDWTSSDRGVDSPGGAG------GGGGSEAAGSARD--------------------------------
--------------RRPPVSVVERNARVIQWLY-GCQRAR--GPPRESEV------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------
>Pan_troglodytes_FAM110D
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------MLLAPPSTPSRGRTPS------
------------------------------------------------------------------------------AV
ERL-----------------------------------------------------------------------------
-------------------------------------------EADKAKYVKTHQVIARRQEPALRG-------------
-------------------------------------------------------------SP---GPLTPHPCNELGP-
--------------------------------------------------------------------------------
-----------------------PASPRTPRPVRRGSGRRLPRP------------------------------------
-----------------DSLIFYRQKRDCKASVNKE--------------------------------------------
-------------------------------NAKGQG----------------------------------LVRRLFLGA
PRDAAPSSP-----------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------ASTERPAASGG----------WAAPQDAP----
--------------------------------------------------------------EAAGKRALCPTCS-----
--------------------------------------------------------------------------------
--LPLSEKERFFNYCGLERALVEVLG-----------------------------------AERFSPQSWGADASPQA--
GTSPP-PGSGDASDWTSSDRGVDSPGGAS------GGGGSEAAGSARD--------------------------------
--------------GRPPVSVVERNARVIQWLY-GCQRAR--GPPRESEV------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------
>Gorilla_gorilla_FAM110D
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------MLLAPPSTPSRGRTPS------
------------------------------------------------------------------------------AV
ERL-----------------------------------------------------------------------------
-------------------------------------------EADKAKYVKTHQVIARRQEPALRG-------------
-------------------------------------------------------------SP---GPLTPHPCNELGP-
--------------------------------------------------------------------------------
-----------------------PASPRTPRPVRRGSGRRLPRP------------------------------------
-----------------DSLIFYRQKRDCKASVNKE--------------------------------------------
-------------------------------NAKGQG----------------------------------LVRRLFLGA
PRDAAPSSP-----------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------ASTERPAASGG----------WAAPQDAP----
--------------------------------------------------------------EAAGKRALCPTCS-----
--------------------------------------------------------------------------------
--LPLSEKERFFNYCGLERALVEVLG-----------------------------------AERFSPQSWGADASPQA--
GTSPP-PGSGDASDWTSSDRGVDSPGGAG------GGGGSEAAGSARD--------------------------------
--------------GRPPVSVVERNARVIQWLY-GCQRAR--GPPRESEV------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------
>Pongo_abelii_FAM110D
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------MLLAPPSTPSRGRTPS------
------------------------------------------------------------------------------AV
ERL-----------------------------------------------------------------------------
-------------------------------------------EADKAKYVKTHQVIARRQEPALRG-------------
-------------------------------------------------------------SP---GPLTPHPCNELGP-
--------------------------------------------------------------------------------
-----------------------PASPRTPRPARRGSGRRLPRP------------------------------------
-----------------DSLIFYRQKRDCKASVNKE--------------------------------------------
-------------------------------NAKGQG----------------------------------LVRRLFLGA
PRDAAPSSP-----------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------ASTERPAASGG----------WAAPQDAP----
--------------------------------------------------------------EAAGKRALCPTCS-----
--------------------------------------------------------------------------------
--LPLSEKERFFNYCGLERALVEVLG-----------------------------------AERFSPQSWGADASPQA--
GTSPP-PGSGDASDWTSSDRGVDSPDGAG------GGGGSEAAGSARD--------------------------------
--------------GRPPVSVVERNARVIQWLY-GCQRAR--GPPRESEV------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------
>Mus_musculus_FAM110D
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------MLLSSPTTPSRGRTPS------
------------------------------------------------------------------------------AV
ERL-----------------------------------------------------------------------------
-------------------------------------------EADKAKYVKTHQVIVRRQEPALRG-------------
-------------------------------------------------------------GP---GPLTPHPCNELGA-
--------------------------------------------------------------------------------
-----------------------SASPRTPGPARRGSGRRQPRP------------------------------------
-----------------DSLIFYRQKRDCKASVNKE--------------------------------------------
-------------------------------NAKGQG----------------------------------LVRRLFLGA
TRDAAPSSP-----------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------APTERPGAPAG----------WAGSPDTP----
--------------------------------------------------------------EATGKRAVCPTCS-----
--------------------------------------------------------------------------------
--LPLSEKERFFNYCGLERALVEVLG-----------------------------------AERFSPQSWGAEHGPQV--
ATSPP-PGSGDTSDWTSSDRDAGSPDCAG------GGGGSEAAGSARD--------------------------------
--------------GRPTVSVVERNARVIQWLY-GCQRAR--APPRESEV------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------
>Rattus_norvegicus_FAM110D
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------MLLASPTTPSRGRTPS------
------------------------------------------------------------------------------AV
ERL-----------------------------------------------------------------------------
-------------------------------------------EADKAKYVKTHQVIVRRQEPALRG-------------
-------------------------------------------------------------GS---GPLTPHPCNELGA-
--------------------------------------------------------------------------------
-----------------------SASPRTPGPARRGSGRRQPRP------------------------------------
-----------------DSLIFYRQKRDCKASVNKE--------------------------------------------
-------------------------------NAKGQG----------------------------------LVRRLFLGA
TRDAAPSSP-----------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------APTERPGAPAG----------WAGSPDTP----
--------------------------------------------------------------EATGKRALCPTCS-----
--------------------------------------------------------------------------------
--LPLSEKERFFNYCGLERALVEVLG-----------------------------------AERFSPQSWGAEHSPQV--
ATSPP-PGSGDTSDWTSSDRDAGSPDCAG------GGGGSEAAGSARD--------------------------------
--------------GRPTVSVVERNARVIQWLY-GCQRAR--APPRESEV------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------
>Canis_familiaris_FAM110D
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------MILASPSTPSRGRTPS------
------------------------------------------------------------------------------AV
ERL-----------------------------------------------------------------------------
-------------------------------------------EADKAKYVKTHQVIARRQEPALRG-------------
-------------------------------------------------------------GP---GPLTPHACNELGP-
--------------------------------------------------------------------------------
-----------------------PASPRTPRPARRSSGRRLPRP------------------------------------
-----------------DSLIFYRQKRDCKASVNKE--------------------------------------------
-------------------------------NAKGQG----------------------------------LVRRLFLGA
PRDAPSSSP-----------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------GPTERPAAPGV----------WAAPQDAP----
--------------------------------------------------------------EAAGKRALCPTCS-----
--------------------------------------------------------------------------------
--LPLSEKERFFNYCGLERALVEVLG-----------------------------------AERFSPQSWGADASPQP--
GASPP-PGSGDTSDWTSSDGDTDRPDGADRGGG--GGGGSEAAGSARD--------------------------------
--------------GRPPVSVVERNARVIQWLY-GCQRAR--GPPRESEV------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------
>Bos_taurus_FAM110D
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------MLLASPSTPSRGRTPS------
------------------------------------------------------------------------------AV
ERL-----------------------------------------------------------------------------
-------------------------------------------EADKAKYVKTHQVIARRQEPALRG-------------
-------------------------------------------------------------GP---GPLTPHTCNELGP-
--------------------------------------------------------------------------------
-----------------------PPSPRTPRPARRGSGRRLPRP------------------------------------
-----------------DSLIFYRQKRDCKASVNKE--------------------------------------------
-------------------------------NAKGQG----------------------------------LVRRLFLGS
PRDVASSSA-----------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------GSSERPAAPGG----------WTAPQDAP----
--------------------------------------------------------------EAAGKRALCPTCS-----
--------------------------------------------------------------------------------
--LPLSEKERFFNYCGLERALVEVLG-----------------------------------AERFSPQSWGADASPQP--
GTSPP-PGSGDASDWTSSEGGADRRDGA-------EGGGSAAAGSERD--------------------------------
--------------GRPQVSVVERNARVIQWLY-GCQRAR--GPPRESEV------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------
>Gallus_gallus_FAM110D
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------MVPLGSTPRAVCTSGRDVSPLRLLNRGPESLRAQLAGGSGGRTPS------
------------------------------------------------------------------------------AV
ERL-----------------------------------------------------------------------------
-------------------------------------------EADKVKYVKSQQVINSRQEPALRGCSP----------
-----------------------------------------------------------CCSPRGRRLLALQRCHELCHG
SDLSCDGSR-----------------------------------------------------------------------
----------------------KAPCPSSPVPRRGGGSRRLLRP------------------------------------
-----------------DSLVIYRQKRDCPV-INKE--------------------------------------------
-------------------------------NTKGYG----------------------------------LVRRLFQGP
LRDKPPSSPSAQGSDKAPESPMLWVS------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------MEQAEDVRTPGAGGSSSSTVPMPDS--------PVPQPPEAPSLAQ
----------------------------------------------------------PPASPSPSKPALGLRLS-----
--------------------------------------------------------------------------------
--LPLSEKERFFNYCGLDRAMVEGLG-----------------------------------KERFVPAGWDAAS-ARLHG
SCEWE---PSQASGCSGED-----------------AGPGEEEPDTRL--------------------------------
--------------C-SAISVVERNARVIKWLY-GCQRAW--AAAKESTV------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------
>Anolis_carolinensis_FAM110D
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------YLRKQLEGTAGMRTPS------
------------------------------------------------------------------------------AV
ERL-----------------------------------------------------------------------------
-------------------------------------------EADKAKYVKSQQVIDRRQEPVLLCYSL----------
-----------------------------------------------------------QSSPCCRRPLARHQRLVVTKD
GLGPKKLPP-----------------------------------------------------------------------
----------------------TPPSPQSPIARRGGG-RRLLRP------------------------------------
-----------------DSLVIYRQKRDCSA-VNKE--------------------------------------------
-------------------------------NTKSYG----------------------------------IVRRLFQSP
LRD-----------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------GHNSRVVSTEG----------VEHPQRDP----
-------------------------------------------------------------GPTDSKRKLCLSSS-----
--------------------------------------------------------------------------------
--LPLSEKERFFNYCGLDRNLVQVLG-----------------------------------AERFKPGTWDARSSGRFPG
SVASA---SSLQHG-SGE------------------EGPAEE-PSEKP--------------------------------
--------------S-TSISLVERNARVIKWLY-SCQQAQ--TAAKESTV------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------
>Danio_rerio_FAM110D_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------MKPLTPIGSPSPLRLLNKGPDYLRRQMDAGSRGRSIS------
------------------------------------------------------------------------------AV
ERL-----------------------------------------------------------------------------
-------------------------------------------EADKAKYVKTQQVINTKQEPVLVP-------------
-----------------------------------------------------------CATP---PPVPRRNLTTSTPS
TPVLLPRNQMVPFSAPSFSRDENED-----DSRKENCRNESDVETNNNANKPPVLSP-----------------------
--------------------RTPLVAPHSAPIMRRSNGKRMLRP------------------------------------
-----------------DSLVIYRQKKECKSP--GE--------------------------------------------
-----------------------------NINGNIEVKGYS------------------------------FVRRLFQGS
MREKSSVNDVAQKTVINEEKASSSRDGDSRMS------------------------------------------------
--------------------------------------------------------------------------------
------------------------------WSNDKDTVDGGVETRRSSKSEREHSSAEIQNNNEEKQPKICLRNSTRNSN
NND---------------------------------------------MDPWKPVIPWKRTNMKRSKSELRLRCS-----
--------------------------------------------------------------------------------
--LAISEQERFFDYCGLDFDMVERLG-----------------------------------PENFLAGASSVDTLSLLLR
SVGGGG---SEPSEFSRHS-----------------GEGIFQEELAEQ--------------------------------
--------------IPTGVSIIERNARVIKWLY-GCRSAAQ-EGPKESTV------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------
>Takifugu_rubripes_FAM110D_b
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------LPGDSKRINMKPLTPIGSPSPLRLLNKGPDYLRRQIDGGGHGRTIS------
------------------------------------------------------------------------------AV
ERL-----------------------------------------------------------------------------
-------------------------------------------EADKAKYVKSQQVINTKQEPVLVP-------------
-----------------------------------------------------------CATP---PPQPRRGVSLPGNV
TPRLPPRSSTTPFSTTSGSLTP-----------KENRRTSVDIEVHNRSNVSFGMPP-----------------------
--------------IPRTPGGNSLVAPHSAPVLRRSSGKRMMRP------------------------------------
-----------------DSLVIYRQKKECKSPSGGT--------------------------------------------
----------------------------VGENNNME------------------------------------SRRSSK-T
ERERSPESLPSHAFGSTLERTR----------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------NGFRNGANEGAKTVATNGNHSSNPDDDADDDPWKRASPQPAARR--
----------------------------------------------------------KFGELRRSKSDLRLRCS-----
--------------------------------------------------------------------------------
--VALSEQDYFFDFCGLDMDMIQRLG-----------------------------------RENFLSGASSIDTLSLALR
SVVGDGCGGSEPSEFSRHS-----------------GDGLFEEELAEQ--------------------------------
--------------LPTGVSIIERNARVIKWLY-GCKNAAE-EGPKESTV------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------
>Gasterosteus_aculeatus_FAM110D_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------MKPLTPVGSPSPLRLLNKGPDYLRRQMDGGGHGRSVS------
------------------------------------------------------------------------------AV
ERL-----------------------------------------------------------------------------
-------------------------------------------EADKAKYVKSQQVINAKQEPALVP-------------
-----------------------------------------------------------CATP---PPQPRRAASIPGSP
APGLAPRRPSNAASSALSGSFASRDENENYDSRKENRRTSVDVEARNRSNANGALPP-----------------------
--------------VPRTPGVGSLVAPHSAPVLRRSTGKRMLRP------------------------------------
-----------------DSLLIYRQKKECKSPHGAA--------------------------------------------
----------------------------AGDNSNTEG------------------------------------------S
TREKA---------AGGEGRIQ----------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------KM--------------------------------------------
--------------------------------------------------------------LRRSESDLRLRCS-----
--------------------------------------------------------------------------------
--AALSEQELFFAFCGLDVDMVDRLG-----------------------------------RTNFLSAASSLGTLSLALR
SVDGDD--RSEPSEFSQHS-----------------GDGLFQEELAEQ--------------------------------
--------------PPTGVSIIERNARVIKWLY-GCRNAAR-EGPKESTV------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------
>Oryzias_latipes_FAM110D_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------SPSPLRLLNKGPDYLRRQIDGGGHGRSIS------
------------------------------------------------------------------------------AV
ERL-----------------------------------------------------------------------------
-------------------------------------------EADKAKYVKSQQVINTKQEPVLVP-------------
-----------------------------------------------------------CATP---PPHTRRAFSTPGSL
TPRLPPRRLSNTPFSISSGSFPSRDENENDDSRKENRRTSVDIEVHNRSNVNYVTPP-----------------------
--------------SPRTPGTNKLVAPHSAPVLRKSTGKRMLRP------------------------------------
-----------------DSLVIYRQKKECKSLSDAA--------------------------------------------
----------------------------AGENNNVDVKGQS------------------------------FVRRLFQGS
MREKN---------GGGEGRIQ----------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------KMVIGLGP--TTKMLQTAQEAVKPTKNEVLSVYPALDPDSDLKT--
----------------------------------------------------------QATELQRSKSDLLLHCS-----
--------------------------------------------------------------------------------
--VAFSEQEHFFDFCGLDMDMIERLG-----------------------------------RQNFLSGASSTDTLSLALR
SVSEDSGGASEPSEFSRHS-----------------GDGLFQEELAEQ--------------------------------
--------------LPTGVSIIERNARVIKWLY-GCKNAAQ-EGPKESTV------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------
>Hydra_magnipapillata_FAM110D
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------MEECEFKEHFRVNRNTFNFLVYELHPLLGKTTTTFREP-----
----------------------------------------------------------------------------ISVV
KRV-----------------------------------------------------------------------------
--------------------------------------------AVALHYLASCEEYRGVSSLFGIG-------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------KSIANLIVHEFINAVN----------------------------------
------------------DILLPKYVKFPLSVEN----------------------------------------------
-----------------------------------------------------------------------LIKHSRDFE
AILG----------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------FQKCIGAVDGCHIP----
--------------------------------------------------------------------------------
IFAPKDQAISYYNYKGWYSIVLFSVVD---------------------------------CRYRFIYTSVGSPGRNNDSY
IFQNSSLKAILESSLFDKCC--------------------KELGDS----------------------------------
---------------LVPLCLIGDSAFPLTRHL-LKPYPKNLELSEI---------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------
>Amphimedon_queenslandica_FAM110D
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------MDNSVFIGARPGDSEQALSSVVNYSTSKS
SFFIVCEIFAIVLQRQTSLLTLTTLAHISSELSIFIDLLPKELLGAVRALCIPNAIYKACATGYSQLAQKSNVLSTPGMH
KNFVTFIGLLLAFNCFTIHDIITYIIKPMFKVYLLHPQQSSQANQGTLSLQFVSLLLRHILVDKYIRGEVNDDGVNIVYP
PFVSHYLLAKSKELSFDVVLNLLKELLKLSKDTLRSSRGTTWGGKTGMSILVESFPSGSQGNEAALIKLRETMELIAEQD
WVREQCSKQDSKQLLHVEKLGDASLSPAQAQYLLHLLIPYCPEDTVKRINESSGSLPPFMTHPEQTVDRILKNLDQWT--
---------------------------------------------------------------------------LHNAL
LHLN----------------------------------------------------------------------------
------------------------------------------LNINSSLHLHSIDHLSQSVIQVFEDSCTEEWTEDSSS-
---------------------------------------------------------QVDGAYCPSIWLVTPLVSELPKS
VLGKILKSAGN---------------------------------------------------------------------
-------------VLGKGQWWNLDRQQERRRSTRASITPTTPNPKTGLQWQQPFLELVLACMNSNHSNHEELLGPLQKQL
TTFLTAFEKDSFPADEQNKSMLYTALKLRLGLVGSMLPSVCSVCESNVLDWVSLLIPLICSGAVDRQPDNSELFTNCLDM
LSALLQALSPDFHMCVFSGGEEGKKSYIMCIKKMKSDLASSKSTCKQEIQQLFP--------------LPQKLYEVTVVK
PPSAFSQQFRIPEKVQG---------------------------------------------------------------
--------------------------------------------------------------------------------
----LRVQEVKEISPWEIIEGIKNSGPFQLSWFGATRIKRKPLKYLEQEKQIQHHTHQHFLSNSGHLLGGSGPSTSRHSV
FLPDSNDSTNGAIGGG----------------------------GGGGGVSSDSGDNAIPPGAASTAGGTRASVGG----
-----------------------------------------------------------------------------TGE
GSGLDNKAEILLQINKMNREQQPSLTTQPGP-----------------------------LPPTFHTTGQVGVSNTPHQL
TQQQPMQRQIPHGMMQQHSAAQMMRPPPHFLQRQLEYMTPEQRNHFMSLPNEE---------------------------
--------------KRVYLSNLQRTFRERRMLEQQQQQQQQQQLMFRHPMHPRPMQVAPPMQMTQVLQQRMMPRYGPQHM
GPPQMHHSGGYMMPGHHPAMFRQPPPGPMYTMHRPPMHHNLPPHHQ----------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------
>Homo_sapiens_FAM110C
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------MRALAALSAP---PNERLLPRDPAATRDPD-AARPARR--------
-----------------------------------------------------------------------------SAV
ERL-----------------------------------------------------------------------------
-------------------------------------------AADRAKYVRGRPGTGRGVAS-----------------
------------------------------------------------------------------EGSGPGAIKCPGND
P-------------------------------------------------------------------------------
----------------------GPPARAPAPVARRAIARKPLRP------------------------------------
-----------------DSLIIYRQK--CEFVRGS---------------------------------------------
-----------------------------GADGPRAS----------------------------------LVKKLFQGP
GKDKAPVP----RT-------------------GDEGKAG----------------------------------------
--------------------------------------------------------------------------------
--------NPETVPTTPGPAADPAIP----ETPAPAAR--S-----AAPSSVPAA---------------PPGPEP-RVV
R----------------------------------------------------------RRGLQRSQSDLSSRYS-----
--------------------------------------------------------------------------------
--AALAESDTFFQYCGLDPEVVEALG-----------------------------------RENFTAGSDC-----VTLK
VRSVS--VATSGSGFSRHSGGD--DEGLQE---------EELIEQVP---------------------------------
----------------STTSVIERNARIIKWLY-TCKKAKETPSQEQSRTRGSKPSR-----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------
>Gorilla_gorilla_FAM110C
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------S---------------------------------------------
-----------------------------GADGPRAS----------------------------------LVKKLFQGP
GKDKAPVP----RT-------------------EDEGKAG----------------------------------------
--------------------------------------------------------------------------------
--------NPETVPTTPGPAADPATP----ETPAPAAR--S-----AAPSSVPAA---------------PPGPEP-RVV
R----------------------------------------------------------RRGLQRSQSDLSSRYS-----
--------------------------------------------------------------------------------
--AALAESDTFFQYCGLDPEVVEALG-----------------------------------RENFTAGSDC-----VTLK
VRSVS--VATSGSGFSRHSGGD--DDGLQE---------EELIEQVP---------------------------------
----------------STTSVIERNARIIKWLY-TCKKAKETPSQEQSRTRGSKPSR-----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------
>Macaca_mulatta_FAM110C
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------L-AAQPEGE--------
-----------------------------------------------------------------------------SAV
ERL-----------------------------------------------------------------------------
-------------------------------------------AADRAKYVRGRPGTGRGVAS-----------------
------------------------------------------------------------------EGSGPGAIKCPGND
--------------------------------------------------------------------------------
----------------------------------RAIARKPLRP------------------------------------
-----------------DSLIIYRQK--CEFMRGA---------------------------------------------
-----------------------------GADGPRAS----------------------------------LVKKLFQGP
GKDKVPVP----RT-------------------GDEGKTG----------------------------------------
--------------------------------------------------------------------------------
--------NPETVPTKPGAAADLAPP----ETPAPAAR--S-----AAPSSVPAA---------------PPGPEP-RVL
R----------------------------------------------------------RRGLQRSQSDLSSRYS-----
--------------------------------------------------------------------------------
--AALAESDTFFQYCGLDPEVVEALG-----------------------------------RENFTAGSDR-----VTLK
VRSVS--VATSGSGFSRHSG-D--DDGLQE---------EELIEQVP---------------------------------
----------------STTSVIERNARIIKWLY-TCKKAKETPSQEQSRTR-----------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------
>Mus_musculus_FAM110C
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------MRALPTLDSL---ARMRPPLGDPRAAEDTL-TPRPANK--------
-----------------------------------------------------------------------------SAV
ERL-----------------------------------------------------------------------------
-------------------------------------------AADRAKYVRSTLGSSRGPVS-----------------
------------------------------------------------------------------EHRVPEAPGVQHRN
P-------------------------------------------------------------------------------
----------------------IPSALAPAPVARRAIARKPLRP------------------------------------
-----------------DSLVIYRQK--CEFVRGS---------------------------------------------
-----------------------------DADCSRVG----------------------------------LMKKFFQGS
GKDKMAVAPETTRV-------------------ADEDKTTKETEATWTKSS-----------------------------
-----QAAAARPASMLPPPTPVVAVKSPAEKTRVANEDKTTKETEATWTKSSQAAAARPASMLPPPTPVVAVKSPAEKTR
VANEDKTTKETEATWTKSSQAAATRPASMLPPPTPVVAVKSPALPFEVAPRVPVG---------------CSGVQL-RVS
R----------------------------------------------------------SKGLQRSQSDLSSRYS-----
--------------------------------------------------------------------------------
--IAKAESDTFFKYCGLDPDVVEALG-----------------------------------RENFSAGSDC-----VTLK
VRSVS--MAASDSSFSRHSE-----DGLQE---------EELLEQVP---------------------------------
----------------STTSVVERNARIIKWLF-TCKKAKETPSQKLQGPA-----------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------
>Rattus_norvegicus_FAM110C
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------MRALPTLDSL---ARTRPSLGDSRAAEGTL-TRQPANK--------
-----------------------------------------------------------------------------SAV
ERL-----------------------------------------------------------------------------
-------------------------------------------AADRAKYVRSTLGSSRGPVS-----------------
------------------------------------------------------------------ENRVPEAPGVQHRN
P-------------------------------------------------------------------------------
----------------------IPSTLAPAPVARRAVARKPLRP------------------------------------
-----------------DSLVIYRQK--CEFVRGS---------------------------------------------
-----------------------------DADSSRVG----------------------------------LMKKFFQGS
GKDKMSVTPETTRV-------------------ADEYKT-----------------------------------------
--------------------------------------------------------------------------------
--------KETEATWTKASQAAAAKPASMLPPPAPVVAMESPALPFEVAPRVPVR---------------RSGVEL-RAS
R----------------------------------------------------------SKGLQRSQSDLSSRYS-----
--------------------------------------------------------------------------------
--TARAESDTFFQYCGLDPEVVESLG-----------------------------------RENFSAASDC-----VTPK
MRSVS--MATSDSSFSRHSE-----DGLQE---------EELLEQVP---------------------------------
----------------STTSVVERNARIIKWLF-TCKKAKETPSQKLQEPA-----------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------
>Canis_familiaris_FAM110C
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------MRALPGLDAP---QRQRPPAQQPEGPRGRD-AAVPARR--------
-----------------------------------------------------------------------------SAA
ERL-----------------------------------------------------------------------------
-------------------------------------------AADRAKYLRGPRGAGPAPEG-----------------
------------------------------------------------------------------SSAGPSAGAAGAPG
P-------------------------------------------------------------------------------
----------------------PAPAPAPGAVARRTVARRPLRP------------------------------------
-----------------DSLVIYRQK--CDFVRGQ---------------------------------------------
-----------------------------GADGPRAG----------------------------------LVRKLFPGP
GRDRAAACPGTARG-------------------DDELRAR----------------------------------------
--------------------------------------------------------------------------------
--------REGAVVSRPGSVGAPAAPGTPRGAPPAPPAPPA-----PPASSAPPA---------------PPGTPR-RAP
AAPPAAPGTPRG---------APAAPPAPPAPPTPPASCAAPRTPASSAPPGPQPRGSRRGGLRRSQSDLSSRYS-----
--------------------------------------------------------------------------------
--ASLAEFDTFFQFCGLDPEVLDALG-----------------------------------RENFSAGSDR-----VTPQ
VRSVS--VATSDSGFSRRSGG---QEGLQE---------EELTEQVP---------------------------------
----------------STTSVVERNARIIKWLY-TCKRAKETPGQGLQGPA-----------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------
>Felis_catus_FAM110C
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------PAGGEG-RAP
-------------------------------------------------------------ELQRSQSDLSSRCS-----
--------------------------------------------------------------------------------
--ASLAEFDTFFQFCGLEPEVVEALG-----------------------------------RENFSAGSDR-----VTLK
VRSVS--VATSDSGFSRHSGG---EEGLQE---------EELTEQVP---------------------------------
----------------STTSVVDRNARIIKWLY-TCKKARETPGQGLQ--------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------
>Xenopus_tropicalis_FAM110C
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MPTDIMHAVRMHPIAELQHPSPAVPLRLLTRGPDYLRRQMEALGSPRANL------
-----------------------------------------------------------------------------SAV
ERL-----------------------------------------------------------------------------
-------------------------------------------AADKAKYVKTPQQQQQGVCVG--------------GS
----------------------------------------------------SSAGGSRGDPRGSSASDSSSGSSRGSQQ
E-------------------------------------------------------------------------------
----------------------GTRGQQGTAPVRRGSSKRSNRP------------------------------------
-----------------DSLVIYRLK--SRGEGQQ---------------------------------------------
------------------------------AEPARVG----------------------------------LVRRLFL--
-KEKPPGS------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------AIPVPPQEHST-----PCPSERLSP------------