>Homo_sapiens_HDGF
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------MHPEGGQFVPQLLGHLLATKLKRFLLSKGG--RRAQIPDVS-RATPHTI
DEMPEAAVKS----TANKYQVFFFGTHETAFLG--PKDLFPYE---ESKEKFGKPNKR--KGFSEGLWEIENNPTVKASG
YQ-----------------------------------------------------SSQKKS-CVEEPEPEPE--AAEG--
--------------------------------------------------------------------------------
-------------------------------------------DGDKKGNAEGSSDE--EGKLVIDEPAKEKNEK-----
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------GALKRRAGDLLEDS---------------------PKR
PKEAENPEGE--------------------------EKEAATLEVERPLPMEVEKNSTPSEPGSG---------------
------------------------------------------------------RGPPQEEE-----EEEDEEEEATKED
AE--------APG-IRDHESL-----------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------
>Pan_troglodytes_HDGF
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------MHPEGGQFVPQLLGHLLATKLKRFLLSKGG--RRAQIPDVS-RATPHTI
DEMPEAAVKS----TANKYQVFFFGTHETAFLG--PKDLFPYE---ESKEKFGKPNKR--KGFSEGLWEIENNPTVKASG
YQ-----------------------------------------------------SSQKKS-CVEEPEPEPE--AAEG--
--------------------------------------------------------------------------------
-------------------------------------------DGDKKGNAEGSSDE--EGKLVIDEPAKEKNEK-----
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------GALKRRAGDLLEDS---------------------PKR
PKEAENPEGE--------------------------EKEAATLEGERPLPMEVEKNSTPSEPGSG---------------
------------------------------------------------------RGPPQEEE-----EEEDEEEEATKED
AE--------APG-IRDHESL-----------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------
>Callithrix_jacchus_HDGF
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------MHPKGGQFVPQLLGHVLATKLKPFLLSKGR--RRAQILDVS-GATPHTI
DEMPEAAVKS----TANKYQVFFFGTHETAFLG--PKDLFPYE---ESKEKFGKPNKR--KGFSEGLWEIENNPTVKASG
YQ-----------------------------------------------------SSQKKS-CVEEPEPEPE--ATEG--
--------------------------------------------------------------------------------
-------------------------------------------DSDKKGNAEGSSDE--EGKLVIDEPAKEKNEK-----
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------GALKRRAGDLLEDS---------------------PKR
PKEAENPEEE--------------------------EKEAATLEGERPLPVEVEKNSTPSEPGSG---------------
------------------------------------------------------RGPPQEEE-----EEEEEEEEAAKED
AE--------VPA-IRDHESL-----------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------
>Mus_musculus_HDGF
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------MSRSNRQKEYKCGDLVFAKMKGYP--HWPARI
DEMPEAAVKS----TANKYQVFFFGTHETAFLG--PKDLFPYE---ESKEKFGKPNKR--KGFSEGLWEIENNPTVKASG
YQ-----------------------------------------------------SSQKKS-CAAEPEVEPE--AHEG--
--------------------------------------------------------------------------------
-------------------------------------------DGDKKGSAEGSSDE--EGKLVIDEPAKEKNEK-----
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------GTLKRRAGDVLEDS---------------------PKR
PKESGDHEEE--------------------------DKEIAALEGERPLPVEVEKNSTPSEPDSG---------------
------------------------------------------------------QGPPAEEE-----EGE---EEAAKEE
AE--------AQG-VRDHESL-----------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------
>Rattus_norvegicus_HDGF
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------MSRSNRQKEYKCGDLVFAKMKGYP--HWPARI
DEMPEAAVKS----TANKYQVFFFGTHETAFLG--PKDLFPYE---ESKEKFGKPNKR--KGFSEGLWEIENNPTVKASG
YQ-----------------------------------------------------SSQKKS-CAEEPEVEPE--AHEG--
--------------------------------------------------------------------------------
-------------------------------------------DGDKKGNAEGSSDE--EGKLVIDEPAKEKNEK-----
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------GMLKRRAGDMLEDS---------------------PKR
PKEPGDHEEE--------------------------EKEIAALEGERPLPVEMEKNSTPSEPDSG---------------
------------------------------------------------------QGPPPEEE-----EGE---EAAAKEE
AE--------AQG-VRDHESL-----------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------
>Felis_catus_HDGF
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------QHPERGRFVPQALGHLPASKLEPRPSAGRG--PRCQTPGSG-VGVGGGI
DEMPEAAVKS----TANKYQVFFFGTHETAFLG--PKDLFPYE---ESKEKFGKPNKR--KGFSEGLWEIENNPTVKASG
YQ-----------------------------------------------------SAPKKS-SVDEPEPEPE--ATEG--
--------------------------------------------------------------------------------
-------------------------------------------DGDKKGSAEGSSDE--EGKLVIDEPAKEKNEK-----
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------GALKRRAGDLLEDS---------------------PKR
PKETEDPEGE--------------------------EKEVAPLEAERPLPVEVEKNRTPSEPGSG---------------
------------------------------------------------------RGLPQEED------EELEEEEAAKED
SE--------APG-IRDRERV-----------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------
>Equus_caballus_HDGF
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------------I
DEMPEAAVKS----TANKYQVFFFGTHETAFLG--PKDLFPYE---ESKEKFGKPNKR--KGFSEGLWEIENNPTVKASG
YQ-----------------------------------------------------SSQKKS-SVEEPEPEPE--ATEG--
--------------------------------------------------------------------------------
-------------------------------------------DGDKKGNAEGSSDE--EGKLVIDEPTKEKNEK-----
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------GALKRRAGDLLEDS---------------------PKR
PKEAEDPEGE--------------------------EKEAATLESERPLPVEVEKNSTRSEPGSG---------------
------------------------------------------------------RGPPQEEE-----EEE-EEEEAAKED
AE--------APG-IRDHESL-----------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------
>Gallus_gallus_HDGF
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------MSRSHRQKEYKCGDLVFAKMKGYP--HWPARI
DEMPEAAVKS----SSNKYQVFFFGTHETAFLG--PKDLFPYE---ECKEKFGKPNKR--KGFSEGLWEIEHNPTVKASG
Y-Q----------------------------------------------------PTQKKT-CPEDAEPEQE---PEG--
--------------------------------------------------------------------------------
-------------------------------------------DGEKKGNAEGSSDE--EGKLVIDEQSKEKNEKA----
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------GIKRKAEDVLEDS---------------------PKR
TKEMEGQE---------------------------AEKKTDNEEAPKEEP---KPNPAEEEKEKN---------------
------------------------------------------------------SDAASVPDAN-EAKQEGKDK------
----------AEEVRDHKESL-----------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------
>Taeniopygia_guttata_HDGF
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------------I
DEMPEAAVKS----SSNKYQVFFFGTHETAFLG--PKDLFPYE---ECKEKFGKPNKR--KGFSEGLWEIENNPTVKASG
Y-Q----------------------------------------------------PTQKKS-CPTAA--ERE---AEG--
--------------------------------------------------------------------------------
-------------------------------------------DGEKKGNAEGSSDE--EGKLVIDEQSKEKNEKG----
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------GTKRKAEDALEDS---------------------PKR
PKDAEGQE---------------------------GDKKVDNEEAPKE-----EPKGNP--GE-----------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------
>Xenopus_tropicalis_HDGF
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------MSRSNRQREYKCGDLVFAKMKGYP--HWPARV
DEVPEPNAKS----SANKYQVFFFGTHETAYLG--SKDIFPYE---ETKEKYGKTNKR--KGFSEGLWEIENNPTVKSSG
HQPSRKRSSTT-------------------------------KAGRGGGAKNSGKAARKKNLEEDEDADADAEEKEEA--
--------------------------------------------------------------------------------
-------------------------------------------DSEKKGNAEGSSDE--EGKLVIDEQSKEKSDK-----
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------TANKRKAEDTAESS---------------------PKK
AKVEDDKEPEKN-----------------------EKEESNEEERVQTPEAGKEKNREPPKPAED---------------
------------------------------------------------------SGKEKVEE-----------KPAVGEE
TK-------------EQKESL-----------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------
>Takifugu_rubripes_HDGF_b
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------MPRSNRQREYKPGDLVFAKMKGYP--HWPARI
DELPEGAVKS----PSNKYQVFFFGTHETALLG--ANDLFPYD---EHKEKFGKAKKR--KGFAEGLWEIENNPTVTHEA
YEPFGD------------------------QFSNLIMFENDSGIEILITATRSSIVMSKKDDASEG--------AGEA--
--------------------------------------------------------------------------------
-------------------------------------------GSPEKADAEGSSDED-EGALVIDEKSEK---------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------GGNKRKVEEPTEVS---------------------PKR
LKDSEGEGDS----------------------------KVD---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------
>Tetraodon_nigroviridis_HDGF_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------MPRSNRQREYKPGDLVFAKMKGYP--HWPARI
DELPEGAVKS----PSNKYQVFFFGTHETALLG--ANDLFPYD---EHKEKFGKAKKR--KGFAEGLWEIENNPTVTHEG
YE------------------------------------------------------SSKKDDASEG--------AGDA--
--------------------------------------------------------------------------------
-------------------------------------------GSPEKADAERSSDED-EGALVIDEKSEK---------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------GGNKRKAEESTEVS---------------------PKR
LKDSEGEGDS----------------------------KVDGNKSNA----EAKLNDVAG--------------------
----------------------------------------------------------ADLKA------EAQEKAPDGGQ
LT--------AEK-------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------
>Homo_sapiens_HDGFL1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------MSAYGMPMYKSGDLVFAKLKGYA--HWPARI
EHMTQP----------NRYQVFFFGTHETAFLS--PKRLFPYK---ECKEKFGKPNKR--RGFSAGLWEIENNPTVQASD
CP-----------------------------------------------------LASEKG-SGDGP--WPEPEAAEG--
--------------------------------------------------------------------------------
-------------------------------------------DEDKPTHAGGGGDE--LGKPDDDKPTEEEK-------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------GPLKRSAGDPPEDA---------------------PKR
PKEAAPDQEEEA-----------EAERAAEAERAAAAAAATAVDEESPFLVAVENGSAPSEPGLV---------------
------------------------------------------------------CEPPQPEEEELREEEVADEEASQEWH
AE--------APG-GGDRDSL-----------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------
>Pan_troglodytes_HDGFL1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------MSDYSMPTYKSGDLVFAKLKGYA--HWPARI
EDMTQP----------NRYQVFFFGTHETAFLS--PKRLFPYK---ECKEKFGKPNKR--RGFSEGLWEIENNPTVQASD
CP-----------------------------------------------------LASEKG-SGDGP--WPEPEAAEG--
--------------------------------------------------------------------------------
-------------------------------------------DEDKPTHAGGGGDE--LGKPDDDKPTEEEK-------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------GPLKRSAGDPPEDA---------------------PKR
PKKAAPDQEEKE-----------EAEAERAAA--AMAAAAAAVDEECPFLVAVENGSAPSEPGLA---------------
------------------------------------------------------CEPPQPEEEELREEEVADEEASQEWH
AE--------APG-GGDRDSL-----------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------
>Macaca_mulatta_HDGFL1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------MSAYGMPMYKSGDLVFAKLKGYA--HWPARI
EHMTQP----------NRYQVFFFGTHETAFLS--PKRLFPYK---ECKEKFGKPNKR--RGFSEGLWEIENNPTVQAAD
CP-----------------------------------------------------LALEKG-GGDGP--RPEPEAAEG--
--------------------------------------------------------------------------------
-------------------------------------------DADKPTHADGGGDD--VGKPHDDKPAEEKEEK-----
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------GPLKRSAGDPPEDA---------------------PKR
PKEAAPDQEEKE-----------EKEE------AEAAAAAATFDEESPLLVAVENGSAPSEPGLA---------------
------------------------------------------------------CEPPQPEEEELREEEVAEEEASQEWH
AE--------APG-GGDRDSV-----------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------
>Bos_taurus_HDGFL1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------MSRFYRRKYKCGDLVFAKLKGYA--HWPARI
EQTAEA----------NRYQVFFFGTHETAFLG--PRHLFPYE---ESKEKFGKPNKR--RGFSEGLWEIENNPTVQASD
YQ-----------------------------------------------------CALEKS-CPEE----PEPEVAEG--
--------------------------------------------------------------------------------
-------------------------------------------GEDPKSHTNGGDDDD-QGKLGVDLPAEEENEK-----
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------ETLKRTAEDPPEDI---------------------PKR
PKEADP--EEGE-----------ERKE--------AAAVAEEAEDARPLLVEVENDPAASVLGLA---------------
------------------------------------------------------WGLPVMEQE--------PEEESAERE
AQ--------APGVGGGHESQ-----------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------
>Loxodonta_africana_HDGFL1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------MSLHNRRK-YKRGDLVFAKLKGFM--HWPARI
EQTYES----------NKYQVFFFGTHETAFLG--PKNLFPYE---ESKEKFGKPNKR--RGFSEGLWEIENNPTVKASD
CH-----------------------------------------------------LSQEKS-CRTEPHHKKT--TTEG--
--------------------------------------------------------------------------------
-------------------------------------------DGDKKRTNEGGGHK--EGKPALDEPTKE--EK-----
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------AALKRGAGDLLEYS---------------------PKR
PKEAELKREE---------------------------KEEVRIDGERPLLVEAENSSTPSEPNSV---------------
------------------------------------------------------CNPPQEKR------EPEEVEEAPKKE
AE--------APE-ARDQESL-----------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------
>Homo_sapiens_HDGFRP2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------MPHAFKPGDLVFAKMKGYP--HWPARI
DDIADGAVKP----PPNKYPIFFFGTHETAFLG--PKDLFPYD---KCKDKYGKPNKR--KGFNEGLWEIQNNPHASYSA
P---------------------PPVSSSDSEAPEANPADGSDADEDDEDRGVMAVTAVTATAASDRMESDSDSDKSSDNS
G--LKRKTPALKMSVS-KRARKASSDLDQA-SVSPSEEENSES-------------------------------------
-----------------------------------------SSESEKTSDQDFTPEKKAAVRAPRRGPLGGRKKKKAPS-
----ASDSDSKADSDG----AKPEPVAMARSASSS---SSSSSSSDSDVSV-----KKPPRGRK-PAEKPLPKPRGRKPK
PERPPSSSSSDSDSD----EVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKE---RRRERADRGEAE-RG
SGGSSGDELREDDEPVKK-RGRKGRGRGPPSSSDSE--------------------------------------------
-------------PEAELEREAKKSAKKPQ--SSSTEPARKPGQKEKRVRPEEKQQAKPVK--VERTRKRSEGFSMDRKV
EKKK---EPSVEEK---LQKLHSEIKFALKVDSPDVKRCLNALEELGTLQVTSQILQKNTDVVATLKKIRRYKANKDVME
KAAEVYTRLKSRVLGPKIEAVQKVNKAGMEKEKAEEKLAGEELAGEEAPQEKAEDKPSTDLSAPVNGEATSQKGESAEDK
EHEEGRDSEEGPRCGSSEDLH--DSVREGPDLDRPGSDRQERERARGDSEALDEES------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------
>Pan_troglodytes_HDGFRP2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------MPHAFKPGDLVFAKMKGYP--HWPARI
DDIADGAVKP----PPNKYPIFFFGTHETAFLG--PKDLFPYD---KCKDKYGKPNKR--KGFNEGLWEIQNNPHASYSA
P---------------------PPVSSSDSEAPEANPAGGSDADEDDEDRGVMAVTAVTATAASDRMESDSDSDKSSDNS
G--LKRKTPALKMSVL-KRARKASSDLDQA-SVSPSEEENSES-------------------------------------
-----------------------------------------SCESEKTSDQDFTPEKKAAVRAPRRGPLGGRKKK-----
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------AKKSAKKLQ--SSSTEPARKPGQKEKRARPEEKQQAKPVK--VERTRKRSEGFSMDRKV
EKKK---EPSVEEK---LQKLHSEIKFALKVDSPDVKRCLNALEELGTLQVTSQILQKNTDVVATLKKIRRYKANKDVME
KAAEVYTRLKSRVLGPKIEAVQKANKAGMEKEKAEEKLAGEELAGEEAPQEKAEDKPSTDLSAPVNGEATSQKGESTEDK
EHEEGRDSEEGPRCGSSEDLH--DSIREGPDLDRPGSDRQERERARGDSEALDEES------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------
>Gorilla_gorilla_HDGFRP2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
P---------------------QPVSSSDSEAPEANPAGGSDADEDDEDRGVMAVTAVTATAASDRMESDSDSDKSSDNS
G--LKRKTPALKMSVS-KRARKASSDLDQA-SVSPSEEENSES-------------------------------------
-----------------------------------------SSESEKTSDQDFTPEKKAAVRAPRRGPLGGRKKKKAPS-
----ASDSDSKADSDG----AKPEPVAMARSASSS---SSSSSSSDSDVSV-----KKPPRGRK-PAEKPPPKPRGRKPK
PERPPSSSSSDSDSD----EVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKE---RRRERADRGEAE-RG
SGGSSGDEFREDDEPVKK-RGRKGRGRGPPSSSDSE--------------------------------------------
-------------PEAELEREAKKSAKKLQ--SSSTEPARKPGQKEKRARPEEKQQAKPVK--VERTRKRSEGFSMDRKV
EKKK---EPSVEEK---LQKLHSEIKFALKVDSPDVKRCLNALEELGTLQVTSQILQKNTDVVATLKKIRRYKANKDVME
KAAEVYTRLKSRVLGPKIEAVQKANKAGMEKEKAEEKLAGEELAGEEAPQEKAEDKPSTDLSAPVNGEATLQKGESAEDK
EHEEGRDSEEGPRCGSSEDLH--DSVREGPDLDRPGSDRQECERARGDSEALDEDS------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------
>Mus_musculus_HDGFRP2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------MPHAFKPGDLVFAKMKGYP--HWPARI
DDIADGAVKP----PPNKYPIFFFGTHETAFLG--PKDLFPYD---KCKDKYGKPNKR--KGFNEGLWEIQNNPHASYSA
P---------------------PPVSSSDSEAPEADLGCGSDVDKDKESRRVMTVTAVTTTATSDRMESDSDSDKSSDHS
G--LKRKTPVLKVSVS-KRARRASSDLDQA-SVSPSEED-SES-------------------------------------
-----------------------------------------PSESEKTSDQDFTPEKKTAARPPRRGPLGGRKKKKVPS-
----ASDSDSKADSDG----AKEEPVVTAQPSPSSSSSSSSSSSSDSDVSV-----KKPPRGRK-PAEKPPPKPRGRRPK
PERPPSTSSSDSDSDSG--EVDRISEWKRRDEERRRELEARRRREQEEELRRLREQEREEKE---RRKERAERG------
--GSSGEELEDE-EPVKK-RSRKARGRGTPSSSDSE--------------------------------------------
-------------PEGELGKEGKKLAKKSQ--LPGSESARKPGQKEKRGRPDEKPRARPVK--VERTRKRSEGLSLERKG
EKKK---EPSVEER---LQKLHSEIKFALKVDNPDVRKCLSALEELGTLQVTSQILQKNTDVVATLKKIRRYKANKDVMA
KAAEVYTRLKSRVLGPKVEALQKVNKAGAEKERADNEKLE-EQPGEQAPRELAEDEPSTDRSAPVNGEATSQKGENMEDR
AQEDGQDSEDGPRGGSSEELH--DSPRDNSDPAKPGNERQDHERTRLASESANDDNEDS---------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------
>Rattus_norvegicus_HDGFRP2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------MPHAFKPGDLVFAKMKGYP--HWPARI
DDIADGAVKP----PPNKYPIFFFGTHETAFLG--PKDLFPYD---KCKDKYGKPNKR--KGFNEGLWEIQNNPHASYSA
P---------------------LPVSSSDSEAPEADLGGGSDADKEKEARRVMTVTAVTTTATSGRTESDSDSDKNSDHS
G--LKRKTPVLKMSVS-KRARKASSDLDQA-SVSPSEED-SES-------------------------------------
-----------------------------------------PSESEKTSDQDFTPEKKTIARAPRRAPLGGRKKKKVPS-
----ASDSDSRADSDG----AKEEPVVTAQPSPSSSSSSSSSSASDSDVSI-----KKPPRGRK-PAEKPPPKPRGRRSK
PERPPSTSSSDSDSDSG--EVDRISEWKRRDEERRRELEARRRREQEEELRRLREQEREEKE---RRKERAERG------
--GSSGEELEDE-EPVKK-RSRKARGRGTPSSSDSE--------------------------------------------
-------------PEGELGKEGKKLAKKSQ--LQGSESARKPGQKEKRGRPDEKPRARPVK--VERTRKRSEGLSLDRKG
EKKK---EPSVEER---LQKLHSEIKFALKVDNPDVRRCLSALEELGTLQVTSQILQKNTDVVATLKKIRRYKANKDVMA
KAAEVYTRLKSRVLGPKVEALQKVNKAGAEKERADGEKVE-EQPGEQAPRELAEDEPSTDRSAPVNGEAASQKGENTEDG
AQEDGQDLEDGPRGGSSEELH--DSPQDSSDPARPGNEHQDHERMQLASESADDDDEDS---------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------
>Canis_familiaris_HDGFRP2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------WPHLLAAQGTIFGFAQRMQMP--NW--KI
DDIADGAVKP----PPNKYPIFFFGTHETAFLG--PKDLFPYD---KCKDKYGKPNKR--KGFNEGLWEIQNNPHASYSA
P---------------------LPVSSSDSEAPEADPAGGS---EDDEVRGVMAVTAVTATAASDRMESDSDSDKSSDNS
G--LKRKAAALKMSVS-KRTRKASSDLDQA-SVSPSEEENSES-------------------------------------
-----------------------------------------SSESEKTSDQDFTPEKKAVVRAPRRGPLAGRKKKKAPS-
----ASDSDSKAESDG----AKVEPVAVARSAPSSSSSSSSSSSSDSDVSV-----KKPPRGRK-PAEKPPPKPRGRKPK
PERPPTSSSSDSDSD----EVDRISEWKRRDEERRRELEARRRREQEEELRRLREQEKEEKE---RRRER-ERGEAPA--
SGGSSGDELGDEDEPVRK-RGRKGRGRGPQSSSDSG--------------------------------------------
-------------PEAELQREAKKTAR------QSTEPTRRPSQKEKRGRPEERPRARPAK--VERTRKRSEGFPPDRKV
EKKK---EPSVEEK---LQKLHSEIKFALKVDNPDVKRCLNALEELGTLQVTSQILQKNTDVVATLKKIRRYKANKEVME
KAAEVYTRLKSRVLGPKIEAIQKATRAGVEKERAEVEKAEEALAGEEAPMERVEDEANADLSAPVNGEATSQKGESMEDK
EQEGGQNSEEGLGCGSSEEPLHNDNAREGSELDAPGKERQERARVRMDSESLDEED------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------
>Pteropus_vampyrus_HDGFRP2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------MPHAFKPGDLVFAKMKGYP--HWPARI
DDIADGAVKP----PPNKYPIFFFGTHETAFLG--PKDLFPYD---KWKDKYGKPNKR--KGFNEGLWEIQNNPHASYSA
P---------------------LPVSSSDSEAPEADPAGGS---EDDEARGVMAVTAVTAAATSDRMESDSDSDKSSENS
G--LKRKASALKMSAS-KRARKASSDLDQA-SMSPSEEENSES-------------------------------------
-----------------------------------------SSESEKTSDQDFTPEKKAVVRAPRRGPLAGRKKKKPPS-
----ASDSDSKPESEG----AKGEPAAVARSASCSSSSASSSSSSDSDVSV-----KKPTRGRK-PAEKPPPKPRGRKPK
PERPPSTSSSDSDSD----EVDRISEWKRRDEQRRRELEARRRREQEEELRRLREREQEEKEEKGRRREQAERGDALRGG
SGASSADELRDEDQPVRKQRVRKGRARGPQSSSDSE--------------------------------------------
-------------AEAELDREAKKSAKKLQ--QQSTEPARRPSQKEKRGRPEEKPRARPAK--VERTRKRSEGFTPERKV
EKKK---EPSVEEK---LQKLHSEIKFALKVDNPDVKRCLNALEELGTLQVTSHILQKNTDVVATLKKIRRYKANKEVME
KAAEVYTRLKSRVLGPKIEAIQKAARTGAEKERTEAEKAEAALGGEDPPSERAEDEASADLSASVNGEATSQKGGSMEDK
EQEEGQNSEEGPVGGSSEDLLHNDSVREGPDLDGPGQDRQERERVHVDSESLDDEDS-----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------
>Monodelphis_domestica_HDGFRP2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------MPHAFKPGDLMKKVLKGGW--QNVPRI
DDIADGAVKP----PPNKYPIFFFGTHETAFLG--PKDLFPYE---KYKDKYGKPNKR--KGFNEGLWEIQNNPHASYSA
P---------------------PPVSSSDSEVPENDPMAGSDAEDEAGL---MAVAAVTAASASEKMESDEESDKGSEHS
G--IKRKAPPLKMPVA-KRARKASSDLDLA-SATPSEDENSES-------------------------------------
-----------------------------------------SSESEKNSDQDFTPEKKTVVRAPRRGLVGGRKKKKVAS-
----GSDSDSKADSEEAH----------NKSVVVTKSDSDSDSDSDSDISV-----KKPSRGRK-PVEKPPPKPRGRKPK
VERVPSSSSSDSDSDS---EVDRISEWKRRDEERRRELEEKRKREQEEELRRLREQEKEEKE---RKKERAEKED-----
--THPNSDSSEAEIKDDEPIKKRGKKGRGRAPSTSD--------------------------------------------
-------------SEPELEKEVKKPTKKPQ--SQSLEPSKKPNQKEKRSRPEEKSRAKPVK--VERARKKSEVLP-ERRV
EKKK---EPSVEEK---LQKLHSEIKFALKVDNPDVKRCLSALEELGSLQVTSQILQKNTDVVATLKKIRRYKANQEVME
KAAEVYTKLKSRVLGPKVEANQKANKPALEKVKAEVEKIEDQLAGGEAPKEKTEEEPSADISTPVNGESTTQKGESGEDK
EQEEGQNMGEGQRCGSSEDLHNDNIQE-DPELDRPGNDRQDRERVRMDSESLDEES------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------
>Gallus_gallus_HDGFRP2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------MPHSFKPGDLVFAKMKGYP--HWPARI
DDIADGAVKP----PPNKYPIFFFGTHETAFLG--PKDLFPYE---KYKDKYGKPNKR--KGFNEGLWEIQNNPHASYSA
P---------------------PPASSSDSDIPENDPMGGSDAGDDEDD---AAMAAVTTEKMESDEDSDR----GSDHS
G--LKRKSLAMKMPVA-KRPRKSSSE-DQG-SPSLTEEENSET-------------------------------------
-----------------------------------------SSESEKNSDQDFTPEKKPVARAPRRMPAGGRKKKKVES-
----GSDSDSKVDSDSEMG---------NATVDMTKSDSNSDSDSD--VSV-----KKPQRGRK-PAEKPPPKPRGRKPK
LERVPISSSSDSDSDS---DVDRISEWKRRDEERRRELEEKRKREQEEEIRRLREQEKEEKE---KRKEKAEKGE-----
--EVHSDSDSS----ADDEVAKKGRKGRGKAPSSSD--------------------------------------------
-------------SELEMEKEVKKPTKKQ-----PSELSRKPNQKEKRGRAEEKPRNKPLK--VERGRKKSDLIP-ERRM
EKKKAP-EPTVEEK---LQKLHSEIKFALKVDNPDIKRCLNALEELGALQVTSHILQKHTDVVATLKKIRRYKANKDVME
KAAEVYTRLKSRVLGPKMEAIQKANKAGPEKDKGDVEKGQEKLSGGETQNEKGEEEMNADLSGPVNGESLSQKTEGTEEQ
ERDKSRGPGAGELEAPSEEAHNN-----VQDYPSAER-----ERVRGESESVDDAEES----------------------
--------------------------------------------------------------------------------
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-------------------------------------------------
>Anolis_carolinensis_HDGFRP2
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-----------------------------------------------------MSQEFKPGDLIFAKMKGYP--HWPARV
DEVPDGAVKP----PTNKMPIFFFGTHETAFLG--PKDIFPYA---ENKEKYGKPNKR--KGFNEGLWEIDNNPKVKFSS
QQSQPAVNTADDKETHEDTSLDATEGSEQKMGPKRRKATALKGSVKQDS-LDTEVEIEEKEMETPKED-DSSEKQISEDV
VKSGDVPVPKVARRGRKRKAEKQAELEEATVAA----AAATTVA------------------------------------
-----------------------------------------VVTVPKTSPKRGRPAATEVKIPKPRGRPKLIKPTCPPE-
--------------------------------------SNTVNEEDKTKR---------------------------KGA
DEKIPKKQ-KKDEESQR---EEDKVRKDPDKKEGKKEVETKKKTTTKLG--SASDSEEDGEEQ-----------------
---------------