>Homo_sapiens_SH3GL1
---------------------------------------------------------------------MSVAGLK----
KQFYKAS-QLVSEKVGGAEGT-KLDDDFKEMEKK--------------VDVT----SKAVTEVLARTIEYLQPNPASRAK
LTMLNTVSKIRGQVKN---PGYPQSEGLLGECMIRHG-KELGGE---SNFGDA---LLDAGESMKRLAEVKDSLDIEVKQ
N-FIDPLQNLCEKDLKEIQHHLKKLEGRRLDFDYKKKRQ-----------------------------------------
------GKIPDEELRQALEKFEESKEVAETSMHNLLETDI--EQVSQLSALVDAQLDYHRQAVQILDELAEKLKRR---M
REASSRPKREYKPK------------------PREPFDLGEPE--------------QSNGGFPC---------------
----------TTAPKIA-----------------------------ASSSFRSSDKPIRTPSRSMP-PLDQPSCKALYDF
EPEN-DGELGFHEGD---VITLTN--------------QIDENWYEG------------MLDGQSG-----FFPLSYVEV
LVPLPQ---------------------------------
>Pan_troglodytes_SH3GL1
---------------------------------------------------------------------MSVAGLK----
KQFYKAS-QLVSEKVGGAEGT-KLDDDFKEMEKK--------------VDVT----SKAVTEVLARTIEYLQPNP-----
--------------------------------------------------GDA---LLDAGESMKRLAEVKDSLDIEVKQ
N-FIDPLQNLCEKDLKEIQHHLKKLEGRRLDFDYKKKRQ-----------------------------------------
------GKIPDEELRQALEKFEESKEVAETSMHNLLETD----------------------------------------M
REASSRPKREYKPK------------------PREPFDLGEPE--------------QSNGGFPC---------------
----------TTAPKIA-----------------------------ASSSFRSSDKPIRTPSRSMP-PLDQPSCKALYDF
EPEN-DGELGFREGD---VITLTN--------------QIDENWYEG------------MLDGQSG-----FFPLSYVEV
LVPLPQ---------------------------------
>Callithrix_jacchus_SH3GL1
--------------------------------------------------------------------------------
----------------GAEGT-KLDDDFKEMEKK--------------VDVT----SKAVTEVLARTIEYLQPNPASRAK
LTMLNTVSKIRGQVKN---PGYPQSEGLLGECMIRHG-KELG-E---SNFGDA---LLDAGESMKRLAEVKDSLDIEVKQ
N-FIDPLQNLCEKDLKEIQHHLKKLEGRRLDFDYKKKRQ-----------------------------------------
------GKIPDEELRQALEKFEESKEVAETSMHNLLGTDI--EQVSQLSALVDAQLDYHRQAVQILDELAEKLKRR---M
REASSRPKREYKPK------------------PREPFDLGEPE--------------QSNGGLPC---------------
----------TSAPKIT-----------------------------ASSSFRSSDKPIRTPSRSMR-ECPRPA-------
--------------------------------------------------------------------------------
---------------------------------------
>Mus_musculus_SH3GL1
---------------------------------------------------------------------MSVAGLK----
KQFYKAS-QLVSEKVGGAEGT-KLDDDFKDMEKK--------------VDVT----SKAVAEVLVRTIEYLQPNPASRAK
LTMLNTVSKIRGQVKN---PGYPQSEGLLGECMVRHG-KELGGE---SNFGDA---LLDAGESMKRLAEVKDSLDIEVKQ
N-FIDPLQNLCDKDLKEIQHHLKKLEGRRLDFDYKKKRQ-----------------------------------------
------GKIPDEELRQALEKFEESKEVAETSMHNLLETDI--EQVSQLSALVDAQLDYHRQAVQILEELADKLKRR---V
REASSRPKREFKPR------------------PREPFELGELE--------------QPNGGFPC---------------
----------APAPKIT-----------------------------ASSSFRSSDKPIRMPSKSMP-PLDQPSCKALYDF
EPEN-DGELGFREGD---LITLTN--------------QIDENWYEG------------MLHGQSG-----FFPLSYVQV
LVPLPQ---------------------------------
>Canis_familiaris_SH3GL1
---------------------------------------------------------------------MSVAGLK----
KQFYKAS-QLVSEKVGGAEGT-KLDEDFKEMEKK--------------VDVT----SKAVTEVLARTIEYLQPNPASRAK
LTMLNTVSKIRGQVKN---PGYPQSEGLLGECMIRHG-KELGGE---SNFGDA---LLDAGESMKRLAEVKDSLDIEVKQ
N-FIDPLQNLCDKDLKEIQHHLKKLEGRRLDFDYKKKRQ-----------------------------------------
------GRIPDEELRQALEKFEESKEVAETSMHNLLETDI--EQVSQLCALVDAQLDYHRQAVQILDELADKLKRR---M
RDASSRPKREYKPK------------------PREPFDLGEPE--------------QSNGGFPC---------------
----------ATAPKIP-----------------------------ASSSFRSSDKPIRTPSRSMP-PLDQPSCKALYDF
EPEN-AGELGFHEGD---VITLTN--------------QIDENWVPH------------PRQAHGT-----FLWHELPPP
AVHTALTCAPQTGPQESSSLCSAEGQI------------
>Xenopus_tropicalis_SH3GL1
---------------------------------------------------------------------MSVAGLK----
KQFYKAS-QLVSEKVGGAEGT-KLDDEFKEMEKK--------------VDVT----TKAVTDVLAKTIEYLQPNPASRAK
LSMLNTMSKIRGQVKN---PGYPQPEGVLGETMIKFG-KDLGDE---SNFGDA---LLDAGESMKRLAEVKDSLDIEVKQ
N-FLDPLQNLCDKDLKEIQHHLKKLEGRRLDYDYKKKRQ-----------------------------------------
------GKIPDEELRQAMEKFIESKEVAETSMINLLDTDV--EQVSQLTALVEAQLDYHRQAVQILDELSEKLKDR---V
RESSSRTKREFKPK------------------PRESYEYAESE--------------QSNGGFS----------------
----------NPSSKAP-----------------------------ASSSFRS-EKPARTNNRSSA-PLDQPCCKALYDF
DPEN-DGELGFRESD---IITLTN--------------QIDENWYEG------------MINGQSG-----FFPVNYVEI
LVPLPQ---------------------------------
>Danio_rerio_SH3GL1_a
---------------------------------------------------------------------MSVAGLK----
KQFYKAS-QMVSEKVGGAEGT-KLDEEFKDLERK--------------VDVT----NKAVVEVISKTSEYLQPNPASRAK
LSMLNTMSKIRGQVKS---PGYPQAEGLLGECMGKYG-RELGEE---TNFGGA---LMEVGESMKRLAEVKDSLDIDVKQ
N-FIDPLQGLCDKDLREIQHHLKKLEGRRLDYDYKKKRQ-----------------------------------------
------GKIPDEELRQALEKFHESKEVAEISMYNLLETDI--EQVSQLSSLVESQLQYHRQAVQILDELSDKLRDR---M
KDAQTRPRKEYIPK------------------PKPVIDFGETNE-------------QSNGGYTP---------------
----------SSAPP-MRN---------------------------AESYHQFGRITTRKPR---L-PAEQACCKALYDF
EPEN-EGELGFHEGD---IITLTN--------------QIDENWYEG------------MLRGQSG-----FFPLNYVEV
IVPLPH---------------------------------
>Takifugu_rubripes_SH3GL1_a
---------------------------------------------------------------------MSVAGLK----
KQFYKAS-QMVSEKVGGAEGT-KLDDDFRDLERK--------------VEVT----SKAVVEVISKTSEYLQPNPASRAK
LSMLNTMSKIRGQVKN---PGYPQAEGLLGECMTKYG-RDLGEE---TNFGGA---LVDVGESMKRLAEVKDSLDIDVKQ
N-FIDPLQGLCDKDLKEIQHHLKKLEGRRLDYDYKKKRQ-----------------------------------------
------GKIPDEEVRQALEKFHESKEVAETSMYNLLETDI--EQVSQLSSLVDSQLQYHRQAVQVLDELSDKLRDR---V
NEAQSRPRREYTPK------------------PKPIFDFGDDS--------------HSNGGYSA---------------
----------PMAPPPSRN---------------------------TGRHFLLSFILPPVSS---A-ALEQPSCKALYDF
EPEN-EGELGFHEGD---IITLTN--------------QIDENWYEG------------MLNGQSG-----FFPLNYVEV
LIPLPH---------------------------------
>Tetraodon_nigroviridis_SH3GL1_a
---------------------------------------------------------------------MSVAGLK----
KQFYKAS-QMVSEKVGGAEGT-KLDDDFRDLERK--------------VEVT----SKAVVEVISKTSEYLQPNPASRAK
LSMLNTMSKIRGQVKN---PGYPQAEGLLGECMSKYG-RDLGEE---TNFGGA---LVDVGEAMKRLAEVKDSLDIDVKQ
N-FIDPLQGLCDKDLKEIQHHLKKLEGRRLDYDYKKKRQ-----------------------------------------
------GKIPDEEVRQALEKFHESKEVAETSMYNLLETDI--EQVSQLSSLVDSQLQYHRQAVQVLEELSDKLRDR---V
NEAQSRPRREYTPK------------------PKPIFDFGEDS--------------HSNGGYSA---------------
----------PVALPPSRT---------------------------T------------------A-ALEQPSCKALYDF
EPEN-EGELGFHEGD---IITLTN--------------QIDENWYEG------------MLNGQSG-----FFPLNYVEV
LIPLPH---------------------------------
>Tetraodon_nigroviridis_SH3GL1_b
---------------------------------------------------------------------MSVAGFR----
KQFYKAS-QMVSEKVGGAEGT-KLDEDFKDLERK--------------ADVT----SKAVVELISKTSEYLQPNPATRAK
LTMLGTVSKIRGQVKS---PGYPQPEGLLGECMTKYG-RDMGQN---TGFGGA---LIDFGESMLRLAEVKDSLDIDVKQ
N-FIDPLQTVADKDIKDIQHHLKKLEGRRLDYDYKKKRQ-----------------------------------------
------GKIQDEEIRQALEKFHESKELAEGSMHNLLETDV--EQVSHLSSLVESLVQYHRQASQILEELSENLAKRNVQG
RRTQSRPKREYTPK------------------PRPSFDYGRAD--------------NSNGGFTP---------------
----------AATSPSNYS---------------------------A----------------------AEPCCRALYDF
EPEN-DGELGFREGD---VIRLLS--------------RIDENWLEG------------SLGSRSG-----YFPVNYVEV
TVPLPN---------------------------------
>Gasterosteus_aculeatus_SH3GL1_a
---------------------------------------------------------------------MSVAGFK----
KQFYKAS-QMVSEKVGGAEGT-KLDEDFKDLERK--------------VDVT----SKAVVEVISKTSEYLQPNPASRAK
LSMLNTMSKIRGQVKN---PGYPQAEGLLGECMGKYG-RDLGEE---TNFGGA---LVDVGESMKRLAEVKDSLDIDVKQ
N-FIDPLQGLCDKDLREIQHHLKKLEGRRLDYDYKKKRQ-----------------------------------------
------GKIPDEEVRQALEKFHESKEVAETSMYNLLETDI--EQVSQLSSLVESQLQYHRQAVQVLEELSDKLKDR---M
NDAQTRPRREYTPK------------------PKPIYDFGEDN--------------QSNGGYST---------------
----------SAAPPPSRN---------------------------SGSGIRVASHRKAT-----S-APEQPCCKALYDF
DPEN-EGELGFREGD---VITLTN--------------QIDENWYEG------------MLNSQSG-----FFPLNYVEV
LVPLPH---------------------------------
>Oryzias_latipes_SH3GL1_a
---------------------------------------------------------------------MSVAGLK----
KQFYKAS-QMVSEKVGGAEGT-KLDDDFRDLERK--------------VDVT----SKAVAEVISKTSEYLQPNPASRAK
LSMLNTMSKIRGQVKN---PGYPQAEGLLGECMAKYG-RELGED---TNFGGA---LVDVGESMKRLAEVKDSLDIDVKQ
N-FIDPLQGLCDKDLREIQHHLKKLEGRRLDYDYKKKRQ-----------------------------------------
------GKIPDEEIRQALEKFHESKDVAETSMYNLLETDI--EQVSQLSALVDSQLQYHRQAVQVLEELSDKLRER---M
NEAQSRPRREYTPK------------------PKPIFDFGDNS--------------HSNGGYPT---------------
----------TMAPPPSRN---------------------------PDITKEVQNPLTPACSSL-P-PPEQPSCKALYDF
EPEN-EGELGFHEGD---VITLTN--------------QIDENWYEG------------MLNGQSG-----FFPLNYVEV
LVPLPH---------------------------------
>Drosophila_melanogaster_SH3GL1
---------------------------------------------------------------------MAFAGLK----
KQINKAN-QYMTEKMGGAEGT-KLDMDFMEMERK--------------TDVT----VELVEELQLKTKEFLQPNPTARAK
MAAVKGISKLSGQAKS---NTYPQPEGLLAECMLTYG-KKLGEDN--SVFAQA---LVEFGEALKQMADVKYSLDDNIKQ
N-FLEPLHHMQTKDLKEVMHHRKKLQGRRLDFDCKRRRQAK---------------------------------------
----------DDEIRGAEDKFGESLQLAQVGMFNLLENDT--EHVSQLVTFAEALYDFHSQCADVLRGLQETLQEK---R
SEAESRPRNEFVPK------------------TLLDLNLDGGGGGLN-EDGTPSHISSSASPLPS---------------
---------PMRSPAKSM--------------------------------------------AVTPQRQQQPCCQALYDF
EPEN-PGELAFKEND---IITLLN--------------RVDDNWFEG------------AVNGRTG-----YFPQSYVQV
QVPLPNGN-------------------------------
>Anopheles_gambiae_SH3GL1
---------------------------------------------------------------------MAFAGLK----
KQINKAN-QYVTEKMGGAEGT-KLDLDFMEMERK--------------TDVT----VELVEELQAKTKEYLQPNPTARAK
MAAVK--------------------EGILADCMLTYG-KKLGED---SIFASA---LVEMGDSLKQMADVKYSLDDNIKQ
N-FLEPLHQLQTKDLKEVMHHRKKLQGRRLDFDCKKRRQAKG--------------------------------------
------SQITDDEIRSAEEKFAESLQLAQVGMYNLLENDV--EQVSQLVTFAEGMLDYHSQCSEILKVLVETLNEK---R
EEAAARPKSEFVPK------------------TLADLNIEMLG---S-QDG------MNASPLPS---------------
---------PMRSPAR----------------------------------------------TPMPTKPTQPCCTALYDF
EPEN-PGELGFKEND---VITLIQ--------------RVDENWFEG------------SLNGRNG-----YFPQSYVQV
TVPLPSN--------------------------------
>Homo_sapiens_SH3GL2
---------------------------------------------------------------------MSVAGLK----
KQFHKAT-QKVSEKVGGAEGT-KLDDDFKEMERK--------------VDVT----SRAVMEIMTKTIEYLQPNPASRAK
LSMINTMSKIRGQEKG---PGYPQAEALLAEAMLKFG-RELGDD---CNFGPA---LGEVGEAMRELSEVKDSLDIEVKQ
N-FIDPLQNLHDKDLREIQHHLKKLEGRRLDFDYKKKRQ-----------------------------------------
------GKIPDEELRQALEKFDESKEIAESSMFNLLEMD--IEQVSQLSALVQAQLEYHKQAVQILQQVTVRLEER---I
RQASSQPRREYQPK------------------PRMSLEFPTG------------DSTQPNGGLSH---------------
----------TGTPKP------------------------------------------------SGVQMDQPCCRALYDF
EPEN-EGELGFKEGD---IITLTN--------------QIDENWYEG------------MLHGHSG-----FFPINYVEI
LVALPH---------------------------------
>Pan_troglodytes_SH3GL2
---------------------------------------------------------------------MSVAGLK----
KQFHKAT-QKVSEKVGGAEGT-KLDDDFKEMERK--------------VDVT----SRAVMEIMTKTIEYLQPNPASRAK
LSMINTMSKIRGQEKG---PGYPQAEALLAEAMLKFG-RELGDD---CNFGPA---LGEVGEAMRELSEVKDSLDIEVKQ
N-FIDPLQNLHDKDLREIQHHLKKLEGRRLDFDYKKKRQ-----------------------------------------
------GKIPDEELRQALEKFDESKEIAESSMFNLLEMD--IEQVSQLSALVQAQLEYHKQAVQILQQVTVRLEER---I
RQASSQPRREYQPK------------------PRMSLEFPTG------------DSTQPNGGLSH---------------
----------TGTPKP------------------------------------------------SGVQMDQPCCRALYDF
EPEN-EGELGFKEGD---IITLTN--------------QIDENWYEG------------MLHGHSG-----FFPINYVEI
LVALPH---------------------------------
>Macaca_mulatta_SH3GL2
--------------------------------------------------------------------------------
--------QKVSEKVGGAEGT-KLDDDFKEMERK--------------VDVT----SRAVMEIMTKTIEYLQPNPASRAK
LSMINTMSKIRGQEKG---PGYPQAEALLAEAMLKFG-RELGDD---CNFGPA---LGEVGEAMRELSEVKDSLDIEVKQ
N-FIDPLQNLHDKDLREIQHHLKKLEGRRLDFDYKKKRQ-----------------------------------------
------GKIPDEELRQALEKFDESKEIAESSMFNLLEMD--IEQVSQLSALVQAQLEYHKQAVQILQQVTVRLEER---I
RQASAQPRREYQPK------------------PRMSLEFPTG------------DSTQPNGGLSH---------------
----------TGTPKP------------------------------------------------SGVQMDQPCCRALYDF
EPEN-EGELGFKEGD---IITLTN--------------QIDENWYEG------------MLHGHSG-----FFPINYVEI
LVALPH---------------------------------
>Callithrix_jacchus_SH3GL2
---------------------------------------------------------------------MSVAGLK----
KQFHKAT-QKVSEKVGGAEGT-KLDDDFKEMERK--------------VDVT----SRAVMEIMTKTIEYLQPNPASRAK
LSMINTMSKIRGQEKG---PGYPQAEALLAEAMLKFG-RELGDD---CNFGPA---LGEVGEAMRELSEVKDSLDIEVKQ
N-FIDPLQNLHDKDLREIQHHLKKLEGRRLDFDYKKKRQ-----------------------------------------
------GKIPDEELRQALEKFDESKEIAESSMFNLLEMD--IEQVSQLSALVQAQLEYHKQAVQILQQVTVRLEER---I
RQASSQPRREYQPK------------------PRMSLEFPTG------------DSTQPNGGLSH---------------
----------TGTPKP------------------------------------------------SGVQMDQPCCRALYDF
EPEN-EGELGFKEGD---IITLTN--------------QIDENWYEG------------MLHGHSG-----FFPINYVEI
LVALPH---------------------------------
>Mus_musculus_SH3GL2
---------------------------------------------------------------------MSVAGLK----
KQFHKAT-QKVSEKVGGAEGT-KLDDDFKEMERK--------------VDVT----SRAVMEIMTKTIEYLQPNPASRAK
LSMINTMSKIRGQEKG---PGYPQAEALLAEAMLKFG-RELGDD---CNFGPA---LGEVGEAMRELSEVKDSLDMEVKQ
N-FIDPLQNLHDKDLREIQHHLKKLEGRRLDFDYKKKRQ-----------------------------------------
------GKIPDEELRQALEKFDESKEIAESSMFNLLEMD--IEQVSQLSALVQAQLEYHKQAVQILQQVTVRLEER---I
RQASSQPRREYQPK------------------PRMSLEFATG------------DSTQPNGGLSH---------------
----------TGTPKP------------------------------------------------PGVQMDQPCCRALYDF
EPEN-EGELGFKEGD---IITLTN--------------QIDENWYEG------------MLHGQSG-----FFPINYVEI
LVALPH---------------------------------
>Canis_familiaris_SH3GL2
--------------------------------------------------------------------------------
------------------------------MERK--------------VDVT----SRAVMEIMTKTIEYLQPNPASRAK
LSMINTMSKIRGQEKG---PGYPQAEALLAEAMLKFG-RELGDD---CNFGPA---LGEVGEAMRELSEVKDSLDMEVKQ
N-FIDPLQNLHDKDLREIQHHLKKLEGRRLDFDYKKKRQ-----------------------------------------
------GKIPDEELRQALEKFDESKEIAESSMFNLLEMD--IEQVSQLSALVQAQLEYHKQAVQILQQVTVRLEER---I
RQASSQPRREYQPK------------------PRMSLEFTTG------------DSTQPNGGLSH---------------
----------TGTPKP------------------------------------------------AGAPMDQPCCRALYDF
EPEN-EGELGFKEGD---IITLTN--------------QIDENWYEG------------MLHGQSG-----FFPINYVEI
LVALPH---------------------------------
>Pteropus_vampyrus_SH3GL2
---------------------------------------------------------------------MSVAGLK----
KHFHKAT-QKVSEKVGGAEGT-KLDDDFKEMERK--------------VDVT----SRAVMEIMTKTIEYLQPNPASRAK
LSMINTMSKIRGQEKG---PGYPQAEALLAEAMLKFG-RELGDD---CNFGPA---LGDVGEAMRELSEVKDSLDMEVKQ
N-FIDPLQNLHDKDLREIQHHLKKLEGRRLDFDYKKKRQ-----------------------------------------
------GKIPDEELRQALEKFDESKEIAESSMFNLLEMD--IEQVSQLSALVQAQLEYHKQAVQILQQVTIRLEER---I
RQASSQPRREYQPK------------------PRMSLEFPTG------------DSTQPNGGLSH---------------
----------TGTPKP------------------------------------------------AGAPMDQPCCRALYDF
EPEN-EGELGFKEGD---VITLTN--------------QIDENWYEG------------MLHGQSG-----FFPINYVEI
LVALPH---------------------------------
>Monodelphis_domestica_SH3GL2
---------------------------------------------------------------------MSVAGLK----
KQFHKAT-QKVSEKVGGAEGT-KLDDDFKEMERK--------------VDVT----SRAVMEIMTKTIEYLQPNPASRAK
LSMINTMSKIRGQEKG---PGYPQAEALLAEAMLKFG-RELGDE---CNFGPA---LGDVGEAMRELSEVKDSLDMEVKQ
N-FIDPLQNLHDKDLREIQHHLKKLEGRRLDFDYKKKRQ-----------------------------------------
------GKIPDEELRQALEKFDESKEIAESSMFNLLEMD--IEQVSQLSALVQAQLEYHKQASQILQQVTVRLEER---I
REASSQPRREYQPK------------------PRMSLEFSSG------------DNSQHNGGLSH---------------
----------TSTPKP------------------------------------------------SGAPMDQPCCRALYDF
EPEN-EGELGFKEGD---VITLTN--------------QIDENWYEG------------MLHGQSG-----FFPINYVEI
LVALPH---------------------------------
>Xenopus_tropicalis_SH3GL2
---------------------------------------------------------------------LIIRTQK----
KQMKKIL-QKVSEKVGGAEGT-KLDEDFKEMERK--------------VDVT----SRAVMEIMTKTTEYLQPNPASRAK
LSMLNTMSKIRGQEKG---PGYPQAEALLAEAMFKFG-REIGDE---SNFGLA---LIDVGDAMRELSDIKDCLDIDVKQ
N-FIDPLQNLHDKDLREIQHHLKKLEGRRLDFDYKKKRQ-----------------------------------------
------GKITDDEIRQALEKFDESKEIAESSMFNLLEMDDIVWEASNSNDLLHSYKYFHHPTYRIYLNICIKFYR----I
REASSQPRREYQPK------------------PRMSLELENS---------------QLNGGIAL---------------
----------AGTPKP------------------------------------------------SGAPMDQPCCRALYDF
DPEN-EGELGFKEGD---IITLTN--------------QIDENWYEG------------MLHGQSG-----FFPINYVDI
LVPLPH---------------------------------
>Danio_rerio_SH3GL2_a
---------------------------------------------------------------------MSVAGLK----
KQFHKAT-QRVSEKVGGAEGT-KLDVDFTEMEKK--------------VDTT----SRAVLDILTKTTEYLQPNPATRAK
MSMMSSMSKIRGGDKG---PGYTQTETTLGEAMQKAG-RELGEE---SCFGVA---LIDVGEAMRELGEVKDALDMEVKQ
N-FIDPLQNIHDKDLKEIQHHLKKLEGRRLDFDYKKKRQ-----------------------------------------
------GKVTEDEIKQALEKFDDSKEIAEQSMFNLLEND--IEQVSQLSALVQAQVNYHRQAAEILQQLSSKIEDR---I
REASCKPKREYVPK------------------PRTSLDF----------------SENHNGSIG----------------
----------HSGPSRS-------------------------------P-----------------APMDQPCCRALYDF
DPEN-EGELGFKEGD---IITLTS--------------KIDDNWYEG------------MVNGQSG-----FFPVNYVDI
LVALPH---------------------------------
>Takifugu_rubripes_SH3GL2_a
---------------------------------------------------------------------MSVAGLK----
KQFHKAT-QKVSEKVGGAEGT-KLDDDFREMEKK--------------VDVT----SRAVLDIMTKTTEYLQPNPASRAK
LSMINTMSKIRGQEKG---PGYPQAETVLGDTMLKFG-RELGED---SSFGSA---LIEASEAMKELGEVKDALDMEVKQ
N-FIDPLQNLHDKDLKEIQHHLKKMEGRRLDFDYKKKRQ-----------------------------------------
------GKVQDEEIKQALEKFDESKEIAEQSMFNLLESD--IPEVSQLAALVQAQLEYHRRSAEILQQLSSKMEDR---I
KEASCKPRKEFTPK------------------PRMTLELLPP-------------SESHNGGIHS---------------
----------AKSPGRS-------------------------------P-----------------APMDQPCCRALYDF
EPEN-DGELGFKEGD---IITLTN--------------QIDDNWYEG------------MINGQSG-----FFPINYVDI
LVPLPH---------------------------------
>Takifugu_rubripes_SH3GL2_b
---------------------------------------------------------------------MSVAGLK----
KQFHKAT-QKVSEKVGGAEGT-KLDDDFTEMEKR--------------VDTT----SRAVLDIMTKTTEYLQPNPATRAK
MSMMNSMSRMRGQEKG---PGYTQTEAILGESMQKFG-RELGEE---SSFGLA---LVDIGEAMRELGEVKDALDMEVKQ
N-FIDPLQNLHEKDLKEIQHHLKKLEGRRLDFDYKKKRQ-----------------------------------------
------GKVTEDELKQALEKFDDSKEIAEQSMFNLLECD--IEQVSQLAALVQAQLEYHSRSAEILTQLSSKIDER---I
REASGKPRKEFAPK------------------PRTSLDFSI--------------SENHNGGIHG---------------
----------ARSPARS-------------------------------P-----------------APMDQPCCRALYDF
DPEN-EGELGFKEGD---IITLTN--------------KIDDNWFEG------------MLHGNSG-----FFPINYVDT
LVPLPH---------------------------------
>Tetraodon_nigroviridis_SH3GL2_b
---------------------------------------------------------------------MSVAGLK----
KQFHKATQQKVSEKVGGAEGT-KLDDDFTEMEKR--------------VDVT----SRAVLDIMTKTTEYLQPNPATRAK
MSMMNSMSRMRGQEKG---PGYTQTEAILGESMQKFG-RELGEE---SSFGLA---LVDIGEAMRD-GEVKDALDMEVKQ
N-FIDPLQNLHEKDLKEIQHHLKKLEGRRLDFDYKKKRQ-----------------------------------------
------AKVTEDELKQALEKFDDSKEIAEQSMFNLLESD--IEQVSQLAALVQAQLEYHSRSAEILTQLSSKIDER---I
REASGKPRKEFVPK------------------PRTSLDFSI--------------SENHNGGIHG---------------
----------ARSPARS-------------------------------P-----------------APMDQPCCRALYDF
DPEN-DGELGFKEGD---IITLTN--------------KIDDNWFEG------------MLHGNSG-----FFPINYVDT
LVPLPH---------------------------------
>Gasterosteus_aculeatus_SH3GL2_a
--------------------------------------------------------------------------------
--------QKVSEKVGGAEGT-KLDDDFKEMEKK--------------VDVT----SRAVLDIMTKTTEYLQPNPASRAK
LSMINTMSKIRGQDKG---PGYPQAESVLGDAMLRFG-RELGDE---SSFGLA---LIDASEAMKELGEVKDALDMEVKQ
N-FIDPLQNLHDKDLKEIQHHLKKMEGRRLDFDYKKKRQ-----------------------------------------
------GKVQDDEIKQALEKFDESKEVAEQSMFNLLESD--IEQVSQLAALVQAQLEYHSRSAEILQQLSSKMEDR---I
KEVSAKPRKEYAPK------------------PRMTLELLPP-------------SESHNGGIHS---------------
----------AKSPGRS-------------------------------P-----------------APLDQPCCRALYDF
EPEN-EGELGFKEGD---VITLTN--------------QIDDNWYEG------------MINGQSG-----FFPINYVDI
LVPLPR---------------------------------
>Oryzias_latipes_SH3GL2_a
--------------------------------------------------------------------------------
-----SS-QKVSEKVGGAEGT-KLDDDFKEMEKK--------------VDIT----SRAVLDIMTKTTEYLQPNPASRAK
LSMINTMSKIRGQDKG---PGYPQAETILGDAMLKFG-RELGEE---SSFGMA---LIDAGESIKELGEVKDALDMEVKQ
N-FIDPLQNLHDKDLKEIQHHLKKMEGRRLDFDYKKKRQ-----------------------------------------
------GKVQDEEIKQALEKFDESKEIAEQSMFNLLESD--IEQVSQLAALVQAQLEYHSRAAEILQQLSSKMEDR---I
KEVSSKPRKEYSPK------------------PRMTLELLPP-------------SESHNGGIHS---------------
----------AKSPGRS-------------------------------PVYTSRIGFDSH---SLAAPMDQPCCRALYDF
EPEN-EGELGFKEGD---IITLTN--------------QIDDNWYEG------------MINGQSG-----FFPINYVDI
LVPLPH---------------------------------
>Ciona_intestinalis_SH3GL2
---------------------------------------------------------------------MSLGGMK----
KQLNKAS-QYMSEKMGETEKT-KMDEEFIEMERK--------------VDAT----QKAVTDLINHTREYLQPNPAVRAK
MNMMN---KLQG--KD---MKYRQVEGVLGEVMVKHG-TDLGHE---SNFGEA---LKEVGEGMIQLSEIKDSLDVSVKQ
D-FIDPFYQSFDKDMKEVLHHRKKLSGRRLDYDYKRKKG-----------------------------------------
------AKVPHEEVVQAEQKLDESLELAGSSMFNLLAGDV--EQVRQLAALVEAQLEYHRQSADILESVNDKLNKQ---I
EEINSKPEKERTKR------------------QLRTSSIAPADR----------TPTHTTPAIP----------------
----------QASPRHTAP---------------------------------------------PPKAT-QPSCKAIFDF
EPEN-EGELAFKEGE---ILTLVA--------------EIDDNWFEG-----------MSQNGDTG-----YFPKTYVEV
VVPL-----------------------------------
>Strongylocentrotus_purpuratus_SH3GL2
---------------------------------------------------------------------MS---FAG-FK
KQLNKAN-QFMSEKIAGAEKT-EYDEEFVDLEKT--------------IDVT----SLAVDDIITKTNELLQPNPLTRAK
QSTAMTVSKMRGQTKN---SRYPQPEATLGDCFLKFG-RDLGEN---SVFGNG---LLEVGEAHKQLADIKDSLDFNIRQ
N-FLEPLDHLRQKELKEIVHHRKKMQGRRLDYDCKKRKV-----------------------------------------
---------------QKGTTFT-----FHVSLFSFLYLHV----------------------KEFFLFLSCTFKNS----
-------CHHYFIG------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------IIALT----------------------------------------------------HFVLA
VCVIT----------------------------------
>Homo_sapiens_SH3GL3
-------------------------------------------------------------MDGIFAGIICNQANR----
CLTWTSQ-QLFSEKISGAEGT-KLDDEFLDMERK--------------IDVT----NKVVAEILSKTTEYLQPNPAYRAK
LGMLNTVSKIRGQVKT---TGYPQTEGLLGDCMLKYG-KELGED---STFGNA---LIEVGESMKLMAEVKDSLDINVKQ
T-FIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKKKRV-----------------------------------------
------GKIPDEEVRQAVEKFEESKELAERSMFNFLENDV--EQVSQLAVFIEAALDYHRQSTEILQELQSKLQMR---I
SAASSVPRREYKPR------------------PVKRS-------------------SSELNGVS----------------
---------TTSVVKTTG----------------------------------------------SNIPMDQPCCRGLYDF
EPEN-QGELGFKEGD---IITLTN--------------QIDENWYEG------------MIHGESG-----FFPINYVEV
IVPLPQ---------------------------------
>Pan_troglodytes_SH3GL3
-------------------------------------------------------------MDGIFAGIICNQANR----
CLTWTSQ-QLFSEKISGAEGT-KLDDEFLDMERK--------------IDVT----NKVVAEILSKTTEYLQPNPAYRAK
LGMLNTVSKIRGQVKT---TGYPQTEGLLGDCMLKYG-KELGED---STFGNA---LIEVGESMKLMAEVKDSLDINVKQ
T-FIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKKKRV-----------------------------------------
------GKIPDEEVRQAVEKFEESKELAERSMFNFLENDV--EQVSQLAVFIEAALDYHRQSTEILQELQSKLQMR---I
SAASSVPRREYKPR------------------PVKRS-------------------SSELNGVS----------------
---------TTSVAKTTG----------------------------------------------SNIPMDQPCCRGLYDF
EPEN-QGELGFKEGD---IITLTN--------------QIDENWYEG------------MIHGESG-----FFPINYVEV
IVPLPQ---------------------------------
>Macaca_mulatta_SH3GL3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MLNTVSKIRGQVKA---TGYPQTEGLLGDCMLKYG-KELGED---STFGNA---LIEVGESMKLMAEVKDSLDINVKQ
T-FIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKKKRV-----------------------------------------
------GKIPDEEVRQAVEKFEESKELAERSMFNFLENDV--EQVSQLAVFIEAALDYHKQSTEILQELQSKLQMR---I
SAASSVPRREYKPR------------------PVKRS-------------------ASELNGVS----------------
---------TTSVVKTTG----------------------------------------------SNIPMDQPCCRGLYDF
EPEN-QGELGFKEGD---IITLTN--------------QIDENWYEG------------MIHGESG-----FFPINYVEV
IVPLPQ---------------------------------
>Mus_musculus_SH3GL3
---------------------------------------------------------------------MSVAGLK----
KQFHKAS-QLFSEKISGAEGT-KLDEEFLNMEKK--------------IDIT----SKAVAEILSKATEYLQPNPAYRAK
LGMLNTVSKLRGQVKA---TGYPQTEGLLGDCMLKYG-KELGED---SAFGNS---LVDVGEALKLMAEVKDSLDINVKQ
T-FIDPLQLLQDKDLKEIGHHLRKLEGRRLDYDYKKRRV-----------------------------------------
------GKIPEEEIRQAVEKFEESKELAERSMFNFLENDV--EQVSQLAVFVEAALDYHRQSTEILQELQSKLELR---I
SLASKVPKREFMPK------------------PVNMS-------------------STDANGVG----------------
---------PSSSSKTPG----------------------------------------------TDTPSDQPCCRGLYDF
EPEN-EGELGFKEGD---IITLTN--------------QIDENWYEG------------MLRGESG-----FFPINYVEV
IVPLPP---------------------------------
>Canis_familiaris_SH3GL3
---------------------------------------------------------------------VKKKKKK----
KRKEKKK-ELFSEKISGVEGT-KLDDEFLDMERK--------------IDIT----NKAVAEILSKATEYLQPNPAYRAK
LGMLNTVSKIRGQVKT---TGYPQTEGLLGDCMLKYG-KELGEG---STFGNA---LIEVGESMKLMAEVKDSLDINVKQ
T-FIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKKKRV-----------------------------------------
------GKIPDEEVRQAVEKFEESKELAERSMFNFLENDV--EQVSQLAVFIEAALDYHKQSTEILQELQSKLQMR---I
SAASSVPKREYKPR------------------PIKRS-------------------PNSGPSLHHYPLP-----------
---------TFSKVMWTG----------------------------------------------SNVAMDQPCCRGLYDF
EPEN-QGELGFKEGD---VITLTN--------------QIDENWYEG------------MLHGESG-----FFPINYVEV
IVPLP----------------------------------
>Xenopus_tropicalis_SH3GL3
---------------------------------------------------------------------HGCKQLL----
TSLFVFL-QLFSEKISGAEGT-KLDDDFQEMERK--------------IDIT----NKVVAELLSKTTEYLQPNPAYRAR
LGMLNTMSKIRGQVKT---TGYPQTEGLLGDCMLRHG-RELGDE---SEFGCA---LLDAGECMKQMAEVKDSLDINVKQ
N-FIDPLQSLQDKDLKEILYHLKRLEGRRLDYDYKKRRQ-----------------------------------------
------GKIPDEEIRQAVEKFEESKELAERSMFNFLENDI--EQVSQLSVFVEAALDYHRQSAQILEDLHNRLHNR---M
NTASSRPKRELQHK------------------SIIAT-LESNE-------------KLHHNGIP----------------
---------SNSSIKPSGWK--------------------------SRAMQLNRVESEDTSGICSSGNLDQPCCRALYDF
EPEN-EGELGFKEGD---IITLTN--------------QIDENWFEG------------MVNGESG-----FFPINYVEV
VVPLP----------------------------------
>Danio_rerio_SH3GL3_a
---------------------------------------------------------------------MSVAGFK----
KQLHKAS-QLLSEKISGAEGT-KLDEDFMEMERK--------------IEVT----NKSVFELITKTTEYLQPNPASRAK
LGMLNTVSKIRGQVKT---TGYPQTEGLLGDCMLRYG-RELGEE---SAFGTA---LADIGEAMKQMADIKDALDISVKQ
N-FIDPLQNLQDKDLKEIVHHLKKLEGRRLDFDYKKKRQ-----------------------------------------
------GKIPDEEIKQAVEKFEESKELAERSMFNFLENDV--RHVSQRXALIEAALEYHRQSLEILKDLDSKLQNR---I
STASRRPKKEFKPK------------------SIVSSLESVE--------------NTQHNGLS----------------
---------HTSSIKSTE----------------------------------------------LESHMDQPCCRSLYDF
EPEN-EGELGFKEGD---IIILTN--------------QIDENWYEG------------MINGESG-----FFPINYVDV
LVPLPQ---------------------------------
>Tetraodon_nigroviridis_SH3GL3_a
---------------------------------------------------------------------MSVAGLK----
KQFHKAS-QLLSEKISGAEGT-RLEEDFVEMERK--------------IDVT----NKSIVELLSKTIEYLQPNPASRAK
LNMLNTVSRIRGQVRT---NGYPQAEGLLGDCMLRYG-QELGED---SVFGGA---LVETGEGLRQMADVKDALDVSVKQ
N-FIDPLQNLQDKELKEITHHLKKLEGRRLDFDYKKKRQ-----------------------------------------
------GKIPGDEIQQAAEKLEESKALAERSMFNFLESDM--EQVSQLASLIEAAKEYHRQSCKILEELFGKLQKR---I
SSASFHPRKEFKPK------------------SIREAMTVFD--------------NSPHDSPS----------------
---------RSASMKSSGP---------------------------------------------ASEVLDQPCCRSLYDF
EPEN-EGELGFKEGD---VIILTN--------------QIDENWYEG------------MIHG-RA-----FFPISYVEV
MVPLPQ---------------------------------
>Gasterosteus_aculeatus_SH3GL3_a
--------------------------------------------------------------------------------
--------QLLSEKISGAEGT-KLDEDFMEMERK--------------IEVT----NKSVFDLLSKTTEYLQPNPASRAK
LNMLNTVSKMRGQVSP---TGYPQTEGLLGDCMLRHG-HELGED---SVFGCA---LVEMGEAMRQMADVKDALDIGVKQ
N-FIDPLQNVQDKDLKEITHHLKKMEGRRLDFDYKKKRQ-----------------------------------------
------GKIPDEEIRQAVEKFDESRELAERSMFNFLENDV--EQVRQLLALIQAAAEYHRQSRDILQELSGKLQKR---I
STASSRPRRDFHQK------------------SIRSSMQPVD--------------SGQHNGLS----------------
---------FSSSLRASG----------------------------------------------TGEPLDQPCCRSLYDF
EPEN-EGELGFKEGD---VIILTN--------------RIDDNWYEG------------MISGESG-----FFPINYVEV
LVPLP----------------------------------
>Homo_sapiens_SH3GLB1
------------------------------------------------------MNIMDF-----------NVKKLAADA
GTFLSRAVQFTEEKLGQAEKT-ELDAHLENLLSK--------------AECT----KIWTEKIMKQTEVLLQPNP----N
ARIEEFVYEKLDRKA----PSRINNPELLGQYMIDAG-TEFGPG---TAYGNA---LIKCGETQKRIGTADRELIQTSAL
N-FLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRNSQLNSARLEGDNIMVNFSYMLNFLHVKWL--
------KSEQ--ELRITQSEFDRQAEITRLLLEGISSTHA--HHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLG-----S
FPSNYLSNNNQTSVTP---------------VPSVLPNAIGSS---------------AMAS-TS---------------
----------GLVI-TS-----------------------------------------PSNLSDLKECSGSRKARVLYDY
DAAN-STELSLLADE---VITVF------------SVVGMDSDWLMG------------ERGNQKG-----KVPITYLEL
LN-------------------------------------
>Pan_troglodytes_SH3GLB1
------------------------------------------------------MNIMDF-----------NVKKLAADA
GTFLSRAVQFTEEKLGQAEKT-ELDAHLENLLSK--------------AECT----KIWTEKIMKQTEVLLQPNP----N
ARIEEFVYEKLDRKA----PSRINNPELLGQYMIDAG-TEFGPG---TAYGNA---LIKCGETQKRIGTADRELIQTSAL
N-FLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRNSQLNSARLEGDNIMIWAEEVT----------
------KSEQ--ELRITQSEFDRQAEITRLLLEGISSTHA--HHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLG-----S
FPSNYLSNNNQTSVTP---------------VPSVLPNAIGSS---------------AMAS-TS---------------
----------GLVI-TS-----------------------------------------PSNLSDLKECSGTRKARVLYDY
DAN--STELSLLAD----VITVF------------SVVGMDSDWLMG------------ERGNQKG-----KVPITYLEL
LN-------------------------------------
>Macaca_mulatta_SH3GLB1
------------------------------------------------------MNIMDF-----------NVKKLAADA
GTFLSRAVQFTEEKLGQAEKT-ELDAHLENLLSK--------------AECT----KIWTEKIMKQTEVLLQPNP----N
ARIEEFVYEKLDRKA----PSRINNPELLGQYMIDAG-TEFGPG---TAYGNA---LIKCGETQKRIGTADRELIQTSAL
N-FLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRNSQLNSARLEGDNIMIWAEEVT----------
------KSEQ--ELRITQSEFDRQAEITRLLLEGISSTHA--HHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLG-----S
FPSNYLSNNNQTSVAP---------------VPSVLPNAIGSS---------------AMAS-TS---------------
----------GLVI-TS-----------------------------------------PSNLSDLKECSGSRKARVLYDY
DAAN-STELSLLADE---VITVF------------SVVGMDSDWLMG------------ERGNQKG-----KVPITYLEL
LN-------------------------------------
>Mus_musculus_SH3GLB1
------------------------------------------------------MNIMDF-----------NVKKLAADA
GTFLSRAVQFTEEKLGQAEKT-ELDAHLENLLSK--------------AECT----KIWTEKIMKQTEVLLQPNP----N
ARIEEFVYEKLDRKA----PSRINNPELLGQYMIDAG-TEFGPG---TAYGNA---LIKCGETQKRIGTADRELIQTSAL
N-FLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETKSSQLNSARPEGDNIMVNFSYMLNFLHVKWL--
------KSEQ--ELRITQSEFDRQAEITRLLLEGISSTHA--HHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLG-----S
FPSNYLSNNNQTSGTP---------------VPYALSNAIGPS---------------AQAS-TG---------------
----------SLVI-TC-----------------------------------------PSNLNDLKESSNNRKARVLYDY
DAAN-STELSLLADE---VITVF------------SVVGMDSDWLMG------------ERGNQKG-----KVPITYLEL
LN-------------------------------------
>Canis_familiaris_SH3GLB1
--------------------------------------------------------------------------------
---------------------------------------------------------------MKQTEVLLQPNP----N
ARIEEFVYEKLDRKA----PSRINNPELLGQYMIDAG-TEFGPG---TAYGNA---LIKCGETQKRIGTADRELIQTSAL
N-FLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETKAS------------------------------
-------SEQ--ELRITQSEFDRQAEITRLLLEGISSTHA--HHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLG-----S
FPSSY-CNNNQTSVAP---------------VPSASSNVIGSS---------------TLTS-TS---------------
----------GLVI-AS-----------------------------------------PTNLNDLKECSGSRKARVLYDY
DAAN-SSELSLLADE---VITVF------------SVVGMDSDWLMG------------ERGNQKG-----RVPITYLEL
LN-------------------------------------
>Myotis_lucifugus_SH3GLB1
------------------------------------------------------MNMMDF-----------NVKKFAADA
GTFLSRAVQFTEEKLGQAEKT-ELDAHLENLLSK--------------AECT----KIWTEKIMKQTEVLLQPNP----N
ARIEEFVYEKLDRKA----PSRVNNPELLGQYMIDAG-TEFGPG---TAYGNA---LIKCGETQKRIGTADRELIQTAAL
N-FLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRAS------------------------------
-------SEQ--ELRITQSEFDRQAEITRLLLEGISSTHA--HHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLG-----S
FPSSYHSNNNQTSVVP---------------VPSASSNVIGSS---------------AMTS--S---------------
----------GLVM-TS-----------------------------------------PSNLIDLKEGSGSRKARVLYDY
DAAN-SSELSLLADE---VITVF------------SVVGMDSDWLMG------------ERGNQKG-----RVPITYLEL
LN-------------------------------------
>Monodelphis_domestica_SH3GLB1
------------------------------------------------------MSIMDF-----------NVKKLAADA
GTFLSRAVQFTEEKLGQAEKT-ELDAHLENLLSK--------------AECT----KQWTEKMMRQTEVLLQPNP----N
ARIEEFVYEKLDRKA----PTRINNQELLGQYMIDAG-NDFGPG---TAYGNA---LIKCGETQKRIGTADRELVQTAAI
N-FLTPLRNFIEGDYKTITKERKLLQNKRLDLDAAKTRLKKAKIAETRALQLNSTQPEGDNIMVNLSYMLNLLHVKWLKI
WAEEVTKSEQ--ELRITQSEFDRQAEITRLLLEGISSTHA--HHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLG-----S
FPSVFVSNNSQSSTTS---------------MSNISTS-SSGIT---------------TSLLPS---------------
----------TSGT-AI-----------------------------------------TPAIGDLKESSGNRKARVLYDY
DAAN-STELSLLADE---VITVY------------SIVGMDSDWLMG------------ERGNQKG-----KVPITYLEL
LN-------------------------------------
>Gallus_gallus_SH3GLB1
------------------------------------------------------MNIMDF-----------NMKKLAADA
GTFLSRAVQFTEEKLGQAEKT-ELDAHLENLLSK--------------AECT----KQWTEKIMKQTEVLLQPNP----N
ARIEEFFYEKLDRKA----PSRMNNPELLGQYMIDAG-NEFGPG---TAYGNA---LIKCGETQKQIGTADRELIQTSAI
N-FLTPLRNFIEGDYKTITKERKLLQNKRLDLDAAKTRLKKAKVAEARAA------------------------------
-------SEQ--EVRITQSEFDRQAEITRLLLEGISSTHA--HHLRCLNDFVEAQMTYYAQCYKYMLDLQKQLG-----S
FPSTFLSNNNQSSSAP---------------VQSVSTPSVLAS---------------ASASLPS---------------
----------VSNS-VV-----------------------------------------TSGISELKSSSGSRKARVLYDY
DAAN-SSELSLLADE---VITVY------------SIPGMDSDWLMG------------ERGNQKG-----KVPITYLEL
LN-------------------------------------
>Xenopus_tropicalis_SH3GLB1
--------------------------------------------------------AMDF-----------NVKKLAADA
GTFLSRAVQFTEEKFGQAEKT-ELDAHLENLLSK--------------AECT----KVWTEKIMKQTEVLLQPNP----N
ARIEEFVYEKLDRKA----PSRLNTEEQLAQYMTDAG-NEFGPG---TAYGNA---LIKCGETQKRIGVAHRELVQTAAI
N-FLTPLRNFIEGDFKTMSKEKKLLQNKRLDLDAAKTRLKKARVTEARAA------------------------------
-------AEQ--ELRITQSEFDRQAEITRLLLEGISSTHA--HHLRCLNDFVEAQMTYFAQSYQYMLDLQKQLG-----S
FPSTFVSNNNQSTLTP---------------MQSVSVPSVSAS-----------------AQAPS---------------
----------AKSS-LV-----------------------------------------TSGFTELKASNGSRKARVLYDY
DAAN-SSELSLLADE---VITVY------------SMPGMDSDWLMG------------ERGHQKG-----KVPITYLEL
LN-------------------------------------
>Danio_rerio_SH3GLB1_a
---------------------------------------------------------MEF-----------NVRRLAADA
GTFLSRAVQFTEEKFGQAEKT-ELDAHLEMLLSR--------------AEST----KHWTEKIMKQTEVVLQPNP----N
VRVEEFLYEILDKKV----PTRANNHEMLGQCMIDSG-HEFGPG---TAYGSA---LIKCGETEKLLGSAEKEFIHSSAI
N-FLTPFRNFIEGDFKTILKERKLLQNKRLDLDAAKNRMKKARVADARSAELNCSPPLGEEYVAHFSYMLSFLHVRWLKL
WTEEVKQAET--ELRIAQSEFDRQAEITRLLLEGISSTHA--HHLRCLNDFVDAQAAYYAQCYQYTVNLQKQLGS-QTAI
FPSTFS-NNNQPSGSS---------------SASVCVPTAPPAA--------------SLPAPPP---------------
----------SQ----A-----------------------------------------SPALNELRSSSGTRKARVLYDY
DAAS-STELSLLADE---VITVS------------SVPGMDSDWLMG------------QRGNQKG-----KVPITYLEL
LN-------------------------------------
>Danio_rerio_SH3GLB1_b
---------------------------------------------------------MDF-----------NVKRFAADA
GTLFSRAVQFTEEKFGQAEKT-ELDAHLETLLTR--------------AECT----KHWTEKILKQTEVLLQPNP----N
ARIEELLYEKLDKKA----PPRMNNHELMGQSMIDSG-NEFGPG---TAYGNA---LIKCGETEKQIGGAEREFIQTSAI
N-FLTPFRNFLEGDFKTILKERKLLQNKRLDLDAAKTKLKKAKMADARAV------------------------------
-------AEQ--DLKMTQSEFDRQAEITRLLLEGISSTHA--HHLRCLNDFVEAQMTYYAQCYQYMVDLQKQLG-----N
FPSAFTSNNNQSTASG---------------GAGVSVPILPLST--------------PLPSTTS---------------
----------N-----T-----------------------------------------SSGFTEMQNFSGSRKARVLYDY
DAAG-SNELSLLADE---VIMVS------------SVPGMDSDWLMG------------ERGSQKG-----KVPITYLEL
LN-------------------------------------
>Takifugu_rubripes_SH3GLB1_a
--------------------------------------------------------TMDF-----------NVKRLAADA
GTFLSRAVQFTEEKFGQAEKT-ELDAHLENLLVR--------------AENT----KLWTERIMKQTEVLLQPNP----N
VRLEEFVYEKLEKKA----PTRMNNHELLGQTMIDSG-SEFGPG---TAYGNA---LMKCGETEKQIGGAEREFIHGAAI
N-FLTPFRNFLEGDFKTILKERKLLQVKRLDLDAAKTRLKKARMADARAA------------------------------
-------AEQ--ELRMTQSEFDRQAEITRLLLEGISSTHA--HHLRCLNDLVEAQTTYYAQCYQYMVDLQKQLG-----S
FPSSFT-NNNQSAASG---------------GASASAPTIPVSA--------------SLPSAGG---------------
----------G---STA-----------------------------------------SGGFNELRSSSASRRARVLYDY
DAAS-SSELSLLADE---VITVS------------SVPGMDSDWLMG------------ERGNQKG-----KVPITYLEL
LN-------------------------------------
>Tetraodon_nigroviridis_SH3GLB1_a
------------------------------------------------------LFNMDF-----------NVKRLAADA
GTFLSRAVQFTEEKFGQAERT-ELDAHLENLLVR--------------AEST----KVWTERIMKQTEVLLQPNPT---D
VRLEEFVYEKLEKKA----PTRMNNHELLGQALMDSG-SECGPG---TAYGNA---LMKCGEAEKLIGGAEREFMQGAAI
N-FLTPLRNFLEGDFKTILKERKLLQVRRLDLDAAKTRLKKARLAEARAA------------------------------
-------AEQ--ELRVTQSEFDRQAEITRLLLEGISSTHA--HHLRCLNDLVEAQSSYYAQCYQYMVDLQKQLG-----S
FPSSFT-NNNQASVSG---------------GAGASAPTIAVSS--------------SLS-------------------
---------------------------------------------------------------ELRGSGASRRARVLYDY
DAAS-SSELSLLADE---VITVS------------SVPGMDSDWLMG------------ERGNQKG-----KVPITYLEL
LN-------------------------------------
>Gasterosteus_aculeatus_SH3GLB1_b
-----------------------------------------------------CGFAMDF-----------NVKRLAADA
GTFLSRAVQFTEEKLGQAEKT-ELDAHLENLLVR--------------AENT----KQWTERIMKQTEVLLQPNP----N
VRLEEFVYEKLEKKA----PTRLNNHDLLGQSMIESG-NEFGPG---TAYGNA---LIKCGETEKQIGGAERELIQSAAI
N-FLTPFRNFLEGDFKTILKERKLLQVKRLDLDAAKTKLKKARMADARAAQGGMTPHV----------------------
---ADPQAEQ--ELRMSQSEFDRQAEITRLLLEGVSSTHA--HHLRCLNDFVEAQTTYYAQCYQYMVDLQKQLG-----R
YHPALG-RLPHQGCDS---------------EDRLSE-------------------------------------------
----------------------------------------------------------SGGFNELRGSNGSRRARVLYDY
DAAS-SSELSLLADE---VDIVIVVS---------SVPGMDSDWLMG------------ERGTQKG-----KVPITYLEL
LN-------------------------------------
>Oryzias_latipes_SH3GLB1_a
---------------------------------------------------------MDF-----------NVKRFAADA
GTFLSRAVQFTEEKLGQAEKT-ELDAHLENLLVR--------------AENT----KQWTEKIMKQTEVLLQPNP----N
VRLEEFVYEKLEKKA----PTRMNNHELLGQSMIESG-SEFGPG---TAYGNA---LIKCGETQKQIGGAEREFIQSAAI
N-FLTPFRNFLEGDFKTILKERKLLQVKRLDLDAAKTRLKKARMSDARAA------------------------------
-------AEQ--ELRMTQSEFDRQAEITRLLLEGVSSTHA--HHLRCLNDLVEAQTTYYAQCYQYMVDLQKQLG-----S
FPSTFS-NNNQ--VSG---------------GASISVPTIPVSA--------------SLPSVSA---------------
----------GQSSLSA-----------------------------------------SAGF------SGSRKARVLYDY
DAAS-SSELSLLADE---AEQP------------CCVPGMAKKW------------------------------------
---------------------------------------
>Drosophila_melanogaster_SH3GLB1
----------------------------------------------------MNINLPNF-----------NVKNLVKEA
GSTISRVVQLTEEKLGTTERT-EYDLHFQNLAER--------------ADVT----KTWTEKIVRDTESVLIPNPQ----
NRVEDFIFEKIEKSK----PKRLSNLEHLALDMIEAG-GDFGQD---LPYGQA---LIKVGQAEQKLGQCEHDFIATSGI
C-FTQPLRKFLDGEMKTIGKERGILETKRLDLDACKNRVKKARSMLGQQSK-DGISPEAVLEQ-----------------
-------AER--DLRVAQAEFDRQAEITKLLLDGISTSQA--SHLRHLHAFIQTQVRYYKQCGDVMEQLQRELA------
NLG--GPTPYIPLDVN---------------EASASKSNISSGAA------------ARGPGNNH---------------
----------SANMAAT---------------------------------------GHKPNQPMHVSTDQMQRARVLCSY
DAKD-HTELNLSAN---EVIFV------------TECSPVNEDYMYG------------KQGLLKG-----LVPRAFVEM
LDEEHDVTL------------------------------
>Anopheles_gambiae_SH3GLB1
----------------------------------------------------MNIKMPDF-----------DVKKFVKGA
GSTLSRVVQLTEEKLGTSEKT-EMDARFEHLSER--------------SDSA----KLWTEKIMRDTEAALIPNPA----
NRVEDFIFEKIEKQK----PKRLSNLEYLGLDMIEGG-GEFGQD---GPYGSA---LIKVGQAEQKLGSCERDFIGSAGM
C-FIQPLKKFLEGEMKTITKEKGVLESKRLDLDACKNRVRKARSMIGQQAK-DGISPEVTLEQ-----------------
-------AER--DLRVAQSEFDRQAEITKLLLEGISTTQA--THLRYLHSLVEAQVRYYGQCNKIMSDLQRELL------
TTL--PTDHNITSRNP---------------DDIRAASSYLGGPQ------------PYVPVSGY---------------
----------EDEDALS---------------------------------------ERVNNIELGANSG-YRRARVLCSY
DAKD-GTELNLSSNEARAVIFV------------CECNPPHSDYMNG------------KQGLLKG-----LVPKAFLEM
LDDD-----------------------------------
>Homo_sapiens_SH3GLB2
---------------------------------------------------------MDF-----------NMKKLASDA
GIFFTRAVQFTEEKFGQAEKT-ELDAHFENLLAR--------------ADST----KNWTEKILRQTEVLLQPNPS----
ARVEEFLYEKLDRKV----PSRVTNGELLAQYMADAA-SELGPT---TPYGKT---LIKVAEAEKQLGAAERDFIHTASI
S-FLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATCEGDTVPDFQETRPRNYILSASASALWNDE
VDK----AEQ--ELRVAQTEFDRQAEVTRLLLEGISSTHV--NHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGSSQGAI
FPGTFVGTTEPASP-----------------PLSSTSPTTAAATM------------PVVPSVAS---------------
----------LAPPGEA----------------------------------------SLCLEEVAPPASGTRKARVLYDY
EAAD-SSELALLADE---LITVY------------SLPGMDPDWLIG------------ERGNKKG-----KVPVTYLEL
LS-------------------------------------
>Pan_troglodytes_SH3GLB2
---------------------------------------------------------MDF-----------NMKKLASDA
GIFFTRAVQFTEEKFGQAEKT-ELDAHFENLLAR--------------ADST----KNWTEKILRQTEVLLQPNPS----
ARVEEFLYEKLDRKV----PSRVTNGELLAQYMADAA-SELGPT---TPYGKT---LIKVAEAEKQLGAAERDFIHTASI
S-FLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKAT----TVPDFQETRPRNYILSASASALWNDE
VDK----AEQ--ELRVAQTEFDRQAEVTRLLLEGISSTHV--NHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGSSQGAI
FPGTFVGTTEPASP-----------------PLSSTSPTTAAATM------------PVVPSVAS---------------
----------LAPPGEA----------------------------------------SLCLEEVAPPASGTRKARVLYDY
EAAD-SSELALLADE---LITVY------------SLPGMDPDWLIG------------ERGNKKG-----KVPVTYLEL
LS-------------------------------------
>Macaca_mulatta_SH3GLB2
---------------------------------------------------------MDF-----------NMKKLASDA
GIFFTRAVQFTEEKFGQAEKT-ELDAHFENLLAR--------------ADST----KNWTEKILRQTEVLLQPNPS----
ARVEEFLYEKLDRKV----PSRVTNGELLAQYMADAA-SELGPT---TPYGKT---LIKVAEAEKQLGAAERDFIHTASI
S-FLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATVDSGTVPDFQETRPRNYILSASASALWNDE
VDK----AEQ--ELRVAQTEFDRQAEVTRLLLEGISSTHV--NHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGSSQGAI
FPGTFVGTTEPASP-----------------PLSSTSPTTAAATM------------PVVPSVAS---------------
----------LAPPGEA----------------------------------------SLCLEEVAPPASGTRKARVLYDY
EAAD-SSELALLADE---LITVY------------SLPGMDPDWLIG------------ERGNKKG-----KVPVTYLEL
LS-------------------------------------
>Mus_musculus_SH3GLB2
---------------------------------------------------------MDF-----------NMKKLASDA
GIFFTRAVQFTEEKFGQAEKT-ELDAHFENLLAR--------------ADST----KNWTERILRQTEVLLQPNPS----
ARVEEFLYEKLDRKV----PSRVTNGELLAQYMAEAA-SELGPS---TPYGKT---LIKVSEAEKRLGAAERDFIHTASL
S-FLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATCEGDTVPDFQETRPRNYILSASASALWNDE
VDK----AEQ--ELRVAQTEFDRQAEVTRLLLEGISSTHV--NHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGSSQGAI
FPGTFVGTTEPASP-----------------PLSSTSPTTTAATM------------PVVPTGAV---------------
----------LAPPEEA----------------------------------------ALCLEEVAPPASGTRKARVLYDY
EAAD-SSELALLADE---LITVY------------SLPGMDPDWLIG------------ERGNKKG-----KVPVTYLEL
LS-------------------------------------
>Canis_familiaris_SH3GLB2
---------------------------------------------------------MDF-----------NMKKLASDA
GIFFTRAVQFTEEKFGQAEKT-ELDAHFENLLAR--------------ADST----KNWTEKILRQTEVLLQPNPS----
ARVEEFLYEKLDRKV----PSRVTNGELLAQYMAEAA-SELGPT---TPYGKT---LIKVAEAEKRLGAAERDFIHTASI
N-FLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATT----VPDFQETRPRNYILSASASALWNDE
VDK----AEQ--ELRVAQTEFDRQAEVTRLLLEGISSTHV--NHLRCLHEFVESQTTYYAQCYRHMLDLQKQLGR-----
FPGTFVGTTEPVSP-----------------PLSSTSPTTAVATM------------PVGPSVAG---------------
----------LAPPGEA----------------------------------------ALRL-EVTPPASGTRKARVLYDY
EAAD-SSELALLADE---LITVY------------SLPGMDPDWLIG------------ERGNKKG-----KVPVTYLEL
LS-------------------------------------
>Xenopus_tropicalis_SH3GLB2
---------------------------------------------------------MDF-----------SVKKLASDA
GVFFSRAVQFTQENLGQAEKT-ELDAHFENLLTR--------------ADNT----KNWTEKILRQTEVLLQPSPS----
ARVEEFLYEKLDRKI----PSRVTTAELLGQYMTEAA-NDFGPS---TPYGQT---LIKVGETQKHLGTAERDFIHSSSI
N-FLTPLRNFLEGDWKTISKERRILQNRRLDLDACKARLKKAKAAEAKAA----ALPDFQETRPRNYILSASASAMYCER
LNYS---AEH--ELRVAQTEFDRQAEVTRLLLEGISSTHV--NHLRCLHEFAEAQATYFAQSYQYMVDLQKQLGR-----
FPAPVVGNTDPASP-----------------PLSTSPPPATLPVL------------QVASSNPG---------------
----------EVP---------------------------------------------LNPVEVPPPVSGTRKARVLYDY
EAAD-SKELSLSADE---LITVY------------SLPGLDPDWLIG------------ERGNKKG-----KVPVTYLEL
LS-------------------------------------
>Danio_rerio_SH3GLB2_a
---------------------------------------------------------MDF-----------NVKKLASDA
GVFFTRAVQYTEEKLGQAEKT-ELDAHLENLIAR--------------ADCT----KNWTEKIFRQTEVLLQPNPS----
ARIEEFFYEKLDKKI----PSRITNAELLGQYMQDAA-KDFGPG---SPYGST---LITVGEYQKRLGGSEREFLQTSAI
N-FLTPLRNFLEGDWKTISRERRLLENRRLDLDVCKARLKKAKLAEAKAA----AAPDFQETRPRNYVLSASASALWSEE
VDK----AEH--ELRVAQTEFDRQAEVTRLLLEGISSTHV--NHLRCLHEFVEAQAAYYAQCHRHMQDLQKELSSANGDT
FPNAFAVNASTSGVSA---------------GPSPLSTGTQPGPS------------SPSRPPNP---------------
----------PNALESN----------------------------------------TLKIEEVKPPATGTRKAKVLYDY
DAAD-TSELSLLADE---LITVY------------TVPGMDPDWLIG------------ERGNQKG-----KVPVTYLEL
LS-------------------------------------
>Takifugu_rubripes_SH3GLB2_a
---------------------------------------------------------MDF-----------NVKKLASDA
GVFFTRAVQFTEEKLGQAEKT-ELDPHLENLISR--------------ADAT----KNWTEKMLRQTEALLQPNPS----
TRIEEFIYDKLDKKL----PSKVTNAELLGQYMLDAA-NDLGPG---TPYGST---LITVGEYQKRLGGAEREFLHIATA
N-FLSPLRNFLEGDWRTISKERRLLENRRLDLDICKARLKKAKQAEAKAA----AAPDFQETRPRNYVLSASASALLSEE
VDK----AEH--ELRVAQTEFDRQAEVTRLLLEGISSTHL--NHLRCLHDFAEAQATYYAQCHHYMQDLQRELSRSGSST
GGHMDLDSSDVEGNN-------------------GLSLTGA--IM------------LLGPLLRL---------------
----------LGAPTHG----------------------------------------TLTVEQLP--VTGTRKAKVLYDY
DAHD-ASELSLLADE---LITVY------------TLPGMDPDWLIG------------ERGNNKG-----KVPVTYLEL
LS-------------------------------------
>Tetraodon_nigroviridis_SH3GLB2_a
---------------------------------------------------------MDF-----------NMKKLASDA
GLFFTRAVQFTEEKLGQAEKT-ELDPHLENLLAR--------------ADAT----KNWTEKVLRQTEALLQPNPS----
ARIEEFIYDKLDRKL----PSKVTNAELLGQHMLDAA-ADLGPE---TPYGST---LTTVGEYQKRLGGAEREFLYIATA
N-FLTPLRNFLEGDWRTISKERRLLENRRLDLDICKARVKKAKQAEAKAA----AAPDFQETRPRNYVLSASASALLSEE
VDK----VRRSRELRVAQTEFDRQAEVTRLLLEGISSTHL--NHLRCLHDFAEAQASYYAQCHHYTQELQRELSRRRRRK
ASAAPAADSSP-----------------------CLFPHRCANPA------------AAAPKPSA---------------
----------AASSSHS----------------------------------------ALGVEQTPLAVTGTRKAKVLYDY
DAHD-ASELSLLADE---LITVY------------TVPGMDPDWLVG------------ERGNDKG-----KVPVTYLEL
LS-------------------------------------
>Gasterosteus_aculeatus_SH3GLB2_b
---------------------------------------------------------MDF-----------NVKKLACGA
GVFFTRAVQFTEEKLGQAEKT-ELDPHLENLITR--------------ADST----KNWTEKILRQTEVLLQPNPS----
ARIEEFIYDKLDKKL----PSRTTNTELLGQYMLEAA-NEFGPG---TPYGST---LITVGEYQKRLGGAERDLLQASAV
G-FLTPLRNFLEGDWRTISKERRLLENRRLDLDICKARLKKAKLAEAKAA----AAPDFQETRPRNYVLSASASALLSEE
ADK----AEH--ELRVAQAEFDRQAEVTKLLLEGIGSTHL--NHLRCLQDFAEAQATYYAQCHHHMQDLQRELS----ST
PHSAPVVCPDP--------------------------VSSAFLSG------------PPSPGASV---------------
----------SSLSSQR----------------------------------------PLAMEQTQLPVTGTRKAKVLYDY
EGHD-GTELSLLADE---LITVH------------TVPGMDPDWLIG------------ERGNQKG-----KVPVTYLEL
LS-------------------------------------