>Homo_sapiens_CLIC1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------MAEE-QPQVELFVK----AGSDG------------------AKIGNCPFSQR
LFMVL---WLKGVTFN--VTTVDTKRRTETVQKLCPGGQLPFLLYGTEV--------HTDTNKIEEFLEAVLCPPRYPKL
AALNPESNTAG--LDIFAKFSAYIKNS--NPALN----DNLEKGLLKALKVLDNYLTSPLPEEVDETS-AEDEGVSQRKF
LDGNELTLADCNLLPKLHIVQ--VVCKKYRGFTIP-EAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVA-------
------KALK----------------------------
>Pan_troglodytes_CLIC1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------MAEE-QPQVELFVK----AGSDG------------------AKIGNCPFSQR
LFMVL---WLKGVTFN--VTTVDTKRRTETVQKLCPGGQLPFLLYGTEV--------HTDTNKIEEFLEAVLCPPRYPKL
AALNPESNTAG--LDIFAKFSAYIKNS--NPALN----DNLEKGLLKALKVLDNYLTSPLPEEVDETS-AEDEGVSQRKF
LDGNELTLADCNLLPKLHIVQ--VVCKKYRGFTIP-EAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVA-------
------KALK----------------------------
>Callithrix_jacchus_CLIC1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------MAEE-QPPVELFVK----AGSDG------------------AKIGNCPFSQR
LFMVL---WLKGVTFN--VTTVDTKRRTETVQKLCPGGQLPFLLYGTEV--------HTDTNKIEEFLEAVLCPPRYPKL
AALNPESNTAG--LDIFAKFSAYIKNS--NPALN----DNLEKGLLKALKVLDNYLTSPLPEEVDETS-AEDEGISQRKF
LDGNELTLADCNLLPKLHIVQ--VVCKKYRGFTIP-EAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVA-------
------KALK----------------------------
>Mus_musculus_CLIC1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------MAEE-QPQVELFVK----AGSDG------------------AKIGNCPFSQR
LFMVL---WLKGVTFN--VTTVDTKRRTETVQKLCPGGQLPFLLYGTEV--------HTDTNKIEEFLEAMLCPPRYPKL
AALNPESNTSG--LDIFAKFSAYIKNS--NPALN----DNLEKGLLKALKVLDNYLTSPLPEEVDETS-AEDEGISQRKF
LDGNELTLADCNLLPKLHIVQ--VVCKKYRGFTIP-EAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVA-------
------RALK----------------------------
>Bos_taurus_CLIC1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------MAEE-QPQVELFVK----AGSDG------------------AKIGNCPFSQR
LFMVL---WLKGVTFN--VTTVDTKRRTETVQKLCPGGQLPFLLYGTEV--------HTDTNKIEEFLEAVLCPPRYPKL
AALNPESNTAG--LDIFAKFSAYIKNS--NPALN----DNLEKGLLKALKVLDNYLTSPLPDEVDETS-AEDEGISQRKF
LDGNELTLADCNLLPKLHIVQ--VVCKKYRGFSIP-DVFRGVHRYLRNAYAREEFASTCPDDEEIELAYEQVA-------
------KALK----------------------------
>Myotis_lucifugus_CLIC1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------LDLT-EPRVEYPVL----AGSDGG-----------------AKIGNCPFSQR
LFMVL---WLKGVTFN--VTTVDTKRRTETVQKLCPGGQLPFLLYGTEV--------HTDTNKIEEFLEAVLCPPRYPKL
AALNPESNTAG--LDIFAKLIGLCQSF--DALANALSCADLEKGLLKALKVLDNYLASPLPEEVDETS-AEDEGISQRKF
LDGNELTLADCNLLPKLHIVQ--VVCKKYRGFSIP-EAFRGVHRYLRNAYAREEFASTCPDDEEIELAYEQVA-------
------KALK----------------------------
>Anolis_carolinensis_CLIC1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------IRPE-SPSGQRIIK----AGSDG------------------AKIGNCPFSQR
LFMVL---WLKGVTFN--VTTVDTKRRTETVQKLCPGGQLPFLMYGTEV--------HTDTNKIEEFLEEVLCPPKYPKL
AARNPESNTAG--LDVFAKYSAYIKNS--NPALN----ANLEKGLLKALKVLDMYLMAPLPEEVDENS-AEDEGQSSRKF
LDGDELTLADCNLLPKLHIVK--VVCKKYRNFTIP-EEFCGIHRYLKNAYAREEFASTCPDDEEIELAYELVA-------
------KALK----------------------------
>Danio_rerio_CLIC1_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------MSEE-RPEVELFVK----AGSDG------------------QSIGNCPFSQR
LFMVL---WLKGVTFN--VTTVDMKRKPEILKDLAPGAQPPFLLYGTEV--------KTDTNKIEEFLEETLCPPKYPRL
AACNPESNTAG--LDVFSKFSAYIKNS--NPQMN----DNLEKGLLKALKKLDDYLSSPLPDEIDENS-ADDVISSTRSF
LDGQELTLADCNLLPKLHIVK--VVCLKFRGFSIP-RSLTSLWRYLDAAYAREEFSSTCPSDEEIYVAYSSVV-------
------KALK----------------------------
>Takifugu_rubripes_CLIC1_b
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------RQQQVKMSDATQPKIELFVK----AGSDG------------------QSIGNCPFSQR
LFMVL---WLKGVTFD--VTTVDMKRKPEILKDLAPGAQPPFLLCGSEV--------KTDTNKIEEFLEEKLCPPKYPRL
AARNPESNTAG--VDVFSKFSAYIKNS--NPQTN----ETLEKGLLKALKKLDDYLGTPLPDEVDQNS-SDDIISSARPF
LDGQELTLADCNLLPKLHIVK--VVCLKYRSFNIP-QSLTNLWRYLNAAYAREEFSSTCPVDEEIHIAYSSVA-------
------KALK----------------------------
>Tetraodon_nigroviridis_CLIC1_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------MSDANQPKIELFVK----AGSDG------------------QSIGNCPFSQR
LFMVL---WLKGVTFD--VTTVDMKRKPDILKDLAPGAQPPFLLYGSEV--------KTDTNKIEEFLEEKLCPPKYPRL
AARNPESNTAG--VDVFSKFSAYIKNS--NPQAN----ENLEKGLLKALMKLDDYLGTPHPDEIDENS-SDDVVSSTRPF
LDGPELTLADCNLLPKLHIVK--VVCLKYRSFTIP-QSLTNLWRYLNAAYAREEFSSTCPIDEEIHIAYSSVA-------
------KALK----------------------------
>Oryzias_latipes_CLIC1_b
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------MVFLSLGIPGTMSDANQPKLELFVK----AGSDG------------------QSIGNCPFSQR
LFMVL---WLKGVTFD--VTTVDMKRKPDILKDLAPGAQPPFLLFGSEV--------KTDTNKIEEFLEETLSPPKYPRL
AARNPESNTAG--LDVFSKFSAYIKNS--NPQAN----ENLEKGLLKALKKLDDYLGSPLPDEVDENS-ADEVTSSSRPF
LDGQNLTLADCNLLPKLHIVK--VVCLKYRNFSIP-DSLTNLWRYLNAAYAKDEFSSTCPVDEEIHSAYSSVA-------
------KALNK---------------------------
>Homo_sapiens_CLIC2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------MSGLRPGTQVDPEIELFV----KAGSD------------------GESIGNCPFCQR
LFMIL---WLKGVKFN--VTTVDMTRKPEELKDLAPGTNPPFLVYNKEL--------KTDFIKIEEFLEQTLAPPRYPHL
SPKYKESFDVG--CNLFAKFSAYIKNTQKEANKN------FEKSLLKEFKRLDDYLNTPLLDEIDPDS-AEEPPVSRRLF
LDGDQLTLADCSLLPKLNIIK--VAAKKYRDFDIP-AEFSGVWRYLHNAYAREEFTHTCPEDKEIENTYANVA-------
------KQKS----------------------------
>Pan_troglodytes_CLIC2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------MSGLRPGTQVDPEIELFV----KAGSD------------------GESIGNCPFCQR
LFMIL---WLKGVKFN--VTTVDMTRKPEELKDLAPGTNPPFLVYNKEL--------KTDFIKIEEFLEQTLAPPRYPHL
SPKYKESFDVG--CNLFAKFSAYIKNTQKEANKN------FEKSLLKEFKRLDDYLNTPLLDEIDPDS-AEEPPVSRRLF
LDGDQLTLADCSLLPKLNIIK--VAAKKYRDFDIP-AEFSGVWRYLHNAYAREEFTHTCPEDKEIENTYANVA-------
------KQKS----------------------------
>Macaca_mulatta_CLIC2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------MSGLRPSTQVDPEIELFV----KAGSD------------------GESIGNCPFCQR
LFMIL---WLKGVKFN--VTTVDMTRKPEELKDLAPGTNPPFLVYNKEL--------KTDFIKIEEFLEQTLAPPRYPHL
SPKYKESFDVG--CNLFAKFSAYIKNTQKEANKN------FEKSLLKEFKRLDDYLNTPLLDEIDPDS-AEEPTVSRRLF
LDGDQLTLADCSLLPKLNIIK--VAAKKYRDFDIP-AEFSGVWRYLHNAYAREEFTYTCPEDKEIENTYASVA-------
------KQKS----------------------------
>Rattus_norvegicus_CLIC2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------MASLALNTQADPEIELFV----KAGSD------------------GESIGNCPFCQR
LFMIL---WLKGVKFN--VTTIDTARKPEELKDLAPGTNPPFLIYNKEL--------KTDFIKIEEFLEKTLAPPRYPHL
SPKYKESFDVG--CNLFAKFSAYIKNTQKEANKN------FEKSLLREFKRLDDYLNTPLLDEIDPDS-TEERTLSRRLF
LDGDQLTLADCSLLPKLNIIK--VAAKKYRDFDIP-AEFSGVWRYLHNAYAREEFAHTCPEDKEIENTYASVA-------
------KQ------------------------------
>Bos_taurus_CLIC2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------MAGPRPSSEADPEIELFV----KAGSD------------------GESIGNCPFSQR
LFMIL---WLKGVKFN--VTTVDMTRKPKELKDLAPGTNPPFLVYNKEL--------KTDFIKIEEFLEQTLAPPRYPHL
SPRNKESFDVG--CNLFAKFSAYIKNTQKEANKT------FEKSLLKEFKRLDDYLNTPLLDEIDPDS-TEELTVSRRLF
LDGDQLTLADCSLLPKLHIIK--VAAKKYRDFDIP-VEFSGVWRYLHNAYAREEFTHTCPEDKEIENTYASVA-------
------KQKS----------------------------
>Myotis_lucifugus_CLIC2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------MAGLRPNIQADPEIELFV----KAGSD------------------GESIGNCPFCQR
LFMIL---WLKGVKFN--VTTVDMTRKPEELKDLAPGANPPFLLYNKEL--------KTDFIKIEEFLEQTLAPPRYPCL
SPKNKESFDVG--SNLFAKFSAYIKNTQKEANKN------FERALLREFKRLDDYLNTPLLDEIDPDS-TEELSVSRRLF
LDGDDLTLADCSLLPKLNIIK--IAAKKYRDFDIP-AEFSGVWRYLHNAYAREEFAHTCPEDKEIEHTYASVA-------
------KQ------------------------------
>Monodelphis_domestica_CLIC2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------MADWGPTAKQEPEIELFV----RAGID------------------GESIGNCPFCHR
LFMVL---WLKGVKFN--VTTVDMTRKPIELKELAPGTNPPFLLFNKEL--------KTDFIKIEEFLEQVLAPPRYPRL
SPKYPESFDVG--CDIFAKFSAYIKNTQ-DTNKH------LEKALLKEFKRLDIYLNTPLPEEIDQDS-AEETVGSRRMF
LDGDQLTLADCNLLPKLHIIK--VVAKKYRDFDIP-AEFSGVWRYLGNAYAREEFRHTCPADKEIESTYASVA-------
------KK------------------------------
>Danio_rerio_CLIC2_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MALRPDSDKEPRIELFI----KAGHD------------------GENVGNCPFCQR
LFMVL---WLKGVKFT--VTTVDMRKKPDELKDLAPGTNPPFLLYNGTL--------KTDFIKIEEFLETTLAPPRYPHL
SPRYKESFDVG--ADIFAKFSAFIKNSPNNAFH--------EKALLREFKRLDDYLNTPLQDELDQN-----ISVSKRKF
LDGNRLTLADCNLLPKLHVIK--VAARKYCNFDIP-TQFTGVWRYLQSAYEREEFSQTCPADIEIEKAYLSVV-------
------KRN-----------------------------
>Takifugu_rubripes_CLIC2_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------HRQNSDREPHIELFI----KAGHD------------------GENVGNCPFCQR
LFMVL---WLKGVKFT--VTTVDMRKKPAELKDLAPGTNPPFLLYNGAL--------KTDFIKIEEFLEQALAPPRYPHL
SPLNKESFDVG--ADIFAKFSAFIKNSPNNAMTS------LEKNLLREFKRLDDYLNSPLPEEIDHNS-TETISVSKRKF
LDGDRLTLADCNLLPKLHVIR--VAAKKYCNFEIP-AHFTGVWRYLENADGRDEFSQTCPADIEIEKAYLSVA-------
------SIRK----------------------------
>Gasterosteus_aculeatus_CLIC2_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------MKRSEFNFLGDDMALRQDSEKEPSVELFI----KAGHD------------------GENVGNCPFCQR
LFMVL---WLKGVKFT--VTTVDMRKKPAELKDLAPGTNPPFLLYNGTL--------KTDFIKIEEFLEQTLAPPRYPHL
SPLSKESFDVG--ADIFAKFSAFIKNSPNNTFH--------EKNLLREFKRLDIYLNSPLPEEIDLNS-RETITVSKRKF
LDGDRLTLADCNLLPKLHVIR--IASKKYCDFDIP-AEFTGVWRYLQNAYQREEFKQTCPADIEIEKTYFTVA-------
------NKTSK---------------------------
>Oryzias_latipes_CLIC2_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------LTLEKPNYSFQQNSEKEPIIELFV----KAGHD------------------GENVGNCPFCQR
LFMVL---WLKGVKFT--VTTVDMRKKPAELKDLAPGTNPPFLLYNGTL--------KTDFIKIEEFLEQTLAPPRYPHL
SPQNKESFDVG--ADIFAKFSAFIKNSPNNAVQ--------KKNLLKEFKRLDDYLNSPLPEEIDHHS-TETISTSNRKF
LDGNRLTLADCNLLPKLHVIM--VASKKYCDFDIP-AHFTGVWRYLQNASEREEFVQTCPADIEIEKAYFSVA-------
------NNRK----------------------------
>Apis_mellifera_CLIC2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------MADDSHENGTS-NGD----VPEIELIIK---ASTID------------------GRRKGACLFCQE
YFMDLYL-LAELKTISLKVTTVDMQKPPPDFRTNFQATPPPILID--NGDAI------LENEKIERHIMKNIPG-GHNLF
VQDKEVATLVE---NLFSKLKLLLLNA-KDKDKDP-----KS---------------SSLMAHLRKID--EHLGRKGTRF
LTGDTMCCFDCELMPRLQHIR--VAGKYFADFEIP-ETLVHLWRYMHHMYRLDAFLQSCPADQDIINHYKLQQ------S
MKMKKHEELETPTFTTSIPIEVNDD-------------
>Homo_sapiens_CLIC3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------MAET---KLQLFVK----ASED------------------GESVGHCPSCQR
LFMVL---LLKGVPFT--LTTVDTRRSPDVLKDFAPGSQLPILLYDSDA--------KTDTLQIEDFLEETLGPPDFPSL
APRYRESNTAG--NDVFHKFSAFIKNP--VPAQD----EALYQQLLRALARLDSYLRAPLEHELAGEP---QLRESRRRF
LDGDRLTLADCSLLPKLHIVD--TVCAHFRQAPIP-AELRGVRRYLDSAMQEKEFKYTCPHSAEILAAYRPAV-------
------HPR-----------------------------
>Pan_troglodytes_CLIC3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------MAET---KLQLFVK----ASED------------------GESVGHCPSCQR
LFMVL---LLKGVPFT--LTTVDTRRSPDVLKDFAPGSQLPILLYDSDA--------KTDTLQIEDFLEETLGPPDFPSL
APRYRESNTAG--NDVFHKFSAFIKNP--VPAQD----EALYQQLLRALARLDSYLRAPLEHELAGEP---QLRESRRRF
LDGDRLTLADCSLLPKLHIVD--TVCAHFRQAPIP-AELRGVRRYLDSALQEKEFKYTCPHSAEILAAYRPAV-------
------HPR-----------------------------
>Macaca_mulatta_CLIC3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------MAET---KLQLFVK----ASED------------------GE-VGHCPSCQR
LFMVL---LLKGVPFT--LTTVDTR-SPDVLKDFAPGSQLPILLYDSDA--------KTDTLQIEDFLEETLGPPDFPSL
APRYRESNTAG--NDVFHKFSAFIKNP--VPAQD----EALYQQLLRALARLDSYLRAPLEHELALEP---QLRESRRRF
LDGDRLTLADCSLLPKLHIVD--TVCAHFRQAPIP-AGLPGVRRYLDSALQEKEFKYTCPHSAEILAAYRPAV-------
------HPR-----------------------------
>Mus_musculus_CLIC3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------MAETT--KLQLFVK----ASED------------------GESVGHCPSCQR
LFMVL---LLKGVPFT--LTTVDTRRALDVLKDFAPGSQLPILLYDGDV--------KTDTLQIEEFLEETLGPPDFPSL
APRYRESNTAG--NDIFHKFSAFIKNP--VPTQD----NALYQQLLRALTRLDSYLRAPLDHELAQEP---HLRESHRRF
LDGDQFTLADCSLLPKLHIVD--TVCAHFRQLPIP-AELSCVRRYLDSALQKKEFKYTCPHSAEILAAYQPAV-------
------HPR-----------------------------
>Canis_familiaris_CLIC3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------MAETA--KLQLFVK----ASED------------------GESVGHCPSCQR
LFMLL---LLKGVPFT--LTTVDTRRSLDVLKDFAPGSQLPILLYDGDA--------KTDTLQIEEFLEETLGPPEFPSL
APRYRESTTAG--NDVFHRFSVFIKNP--VPAQD----NALYQLLLRALTRLDGYLRRPLEHELAQEP---QLQESRRRF
LDGDQLTLADCSLLPKLYIMD--TVCTHFRQVPIP-AELCGVRRYLESALQVKEFKYTCPCSAEILAAYRMAV-------
------HPRYPLPTADRHPVCFSTAP------------
>Pteropus_vampyrus_CLIC3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------MAETA--KLQLFVK----ASED------------------CESVGHCPSCQR
LFMIL---LLKGVPFT--LTTVDTRRSPDVLKDFAPGSQLPILLYDGDA--------KTDTLQIEEFLEETLGPPEFPSL
APRYKESAMAG--SDVFHKFSAFIKNP--APEQD----DALYQLLLRALARLDSYLRAPLEHELVREP---QLRESRRRF
LDGDQLTLADCGLLPKLHIVD--TVCAHFRQAPIP-AQLRGVRRYLDGALQEKEFKYTCPHSAEILAAYRPAV-------
------RPR-----------------------------
>Monodelphis_domestica_CLIC3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------MAENP--KLQLFVK----ASED------------------GESVGNCPFCQR
LFMIL---LLKGVPFT--LTTVDTKRSLDVLKDFAPGSQLPILLYDGEA--------KTDNIQIEEFLEEILGPPKYPSL
VPRYKESNMAG--NDVFHKFSAFIKNT--SPSQD----EAFYRPLLRALVKLDHYLNTPLEHELIRDP---KLTQSRRHF
LDGDQLTLADCNLLPKLHIIN--TVCTYYRQAPIP-AELQGLHRYLENALQVKEFKYTCPHSSEILAAYAPVA-------
------RAHPPPHGIHPSVRP-----------------
>Gallus_gallus_CLIC3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------GTGTRCTVTAQPPPSMDEKP--QIQLFVK----ASED------------------GESVGHCPFCQR
LFMVL---LLKGAPFT--LTTVDTKRALDVLKDFAPGAQLPVLLYNGDS--------KTDTVTIEDFLEARLAPPTFPSL
VPRYKESRLAG--NDIFHKFSTFIKNP--VPAQD----EALQRNLLKALLKLDEYLSTPLEHELAREP---HLRTSQRRF
LDGDQLTLADCNLLPKLNIVQ--IVCQHYRRFGIP-KDLQAVWRYLNNAAETKEFKYTCPSSEEIVQAYRSVV-------
------RSPQ----------------------------
>Danio_rerio_CLIC3_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------MAEAA--KIELFVK----ASDD------------------GESVGNCPFCQR
LFMIL---WLKGVNFT--LTTVDMKRAPEVLKDLAPGSQPPFLIYNGEV--------RTDTNKIEEFLEDTLAPPQYPKL
CCRYKESNTAG--DDIFHKFSAYIKNP--NPGLN----DMLEKKFLKSLMKLDQYLLTPLPHELDQNP---ELSTSTRHY
LDGNALSLADCNLLPKLHIVK--VVCKKYRGFEIP-AELKGLSKYLDKAYKEDVFHLTCPKDKEILLAYSSVA-------
------KYLNK---------------------------
>Gasterosteus_aculeatus_CLIC3_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------INQDYKTAGIKMSEVP--NIELFVK----ASVD------------------ADSVGNCPFSQR
LFMIL---WLKGIKFR--LTTVDMKRAPDVLKTLAPGSQPPFLLYNEEV--------KTDTNKIEEFLEEKLAPPEYPKL
CCRYKESIGAG--DDIFRNFSAYVKNP--NPAFN----ERIEKKFLSTLVKLNMYLETPLPYELDQKP---NATESSRLY
LDGDTLTLADCNLLPKLNIVK--VVCKQYRDFDIP-KELRGLTRYLSNAYKRDEFRHTCPRDSEILIAYQAVA-------
------KYLNK---------------------------
>Oryzias_latipes_CLIC3_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------MSKQHPADNREEKKGMGDEP--NIELFVK----ASLD------------------AESVGNCPFCQR
LFMIL---WLKRAEFV--LTTVDMKRAPEVLKALAPGSQPPFLIFNGEV--------KTDTNKIEEFLEEKLAPPRYPKL
CCTYKESNLAG--EDIFRKFSAYIKNP--NPGLN----IMLEKQFLSTLVKLNMYLETPLPHELERNP---DANESSRLY
LDGNAFTLADCNLLPKLNIVK--VVCKKYRNFDIP-TELKGLTRYLDNAYKQDEFRHTCPQDEEILLAYKSVA-------
------KYLTS---------------------------
>Nematostella_vectensis_CLIC3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------MAEETIPGVELFVK---ASTLD------------------CQSLGADIQCHR
IMMMF---ALKGLPIK--TFNVDTIKKTNVQLHFPYKNFPTLTLDNGAEVLDD---LDEIERRFEKLSETNQSIPKLACT
NKDILSFVNVGPGSKIYQKFNYFIKNR--AQEGE----EALKTQLLQELKKVNAFLMSAKMPKDGEGN---------QMF
LSGESPGLPDCTLLPKLHYIY--VCLGVVKEFPME--ELTGIESYLESGRKHSAFQSTCPKKADIVHFYCRQAGM-----
---DDAEAMRKSNQVRE---------------------
>Homo_sapiens_CLIC4
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------MALSMPLNGLKEEDK-----
--------------------------------------------------------------------------------
---------------------------------EPLIELFVK----AGSD------------------GESIGNCPFSQR
LFMIL---WLKGVVFS--VTTVDLKRKPADLQNLAPGTHPPFITFNSEV--------KTDVNKIEEFLEEVLCPPKYLKL
SPKHPESNTAG--MDIFAKFSAYIKNS--RPEAN----EALERGLLKTLQKLDEYLNSPLPDEIDENS-MEDIKFSTRKF
LDGNEMTLADCNLLPKLHIVK--VVAKKYRNFDIP-KEMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYSDVA-------
------KRLTK---------------------------
>Pan_troglodytes_CLIC4
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------MALSMPLNGLKEEDK-----
--------------------------------------------------------------------------------
---------------------------------EPLIELFVK----AGSD------------------GESIGNCPFSQR
LFMIL---WLKGVVFS--VTTVDLKRKPADLQNLAPGTHPPFITFNSEV--------KTDVNKIEEFLEEVLCPPKYLKL
SPKHPESNTAG--MDIFAKFSAYIKNS--RPEAN----EALERGLLKTLQKLDEYLNSPLPDEIDENS-MEDIKFSTRKF
LDGNEMTLADCNLLPKLHIVK--VVAKKYRNFDIP-KEMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYSDVA-------
------KRLTK---------------------------
>Callithrix_jacchus_CLIC4
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------MALSMPLNGLKEEDK-----
--------------------------------------------------------------------------------
---------------------------------EPLIELFVK----AGSD------------------GESIGNCPFSQR
LFMIL---WLKGVVFS--VTTVDLKRKPADLQNLAPGTHPPFITFNSEV--------KTDVNKIEEFLEEVLCPPKYLKL
SPKHPESNTAG--MDIFAKFSAYIKNS--RPEAN----EALERGLLKTLQKLDEYLNSPLPDEIDENS-MEDIKFSTRKF
LDGNEMTLADCNLLPKLHIVK--VVAKKYRNFDIP-KEMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYSDVA-------
------KRLTK---------------------------
>Mus_musculus_CLIC4
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------MALSMPLNGLKEEDK-----
--------------------------------------------------------------------------------
---------------------------------EPLIELFVK----AGSD------------------GESIGNCPFSQR
LFMIL---WLKGVVFS--VTTVDLKRKPADLQNLAPGTHPPFITFNSEV--------KTDVNKIEEFLEEVLCPPKYLKL
SPKHPESNTAG--MDIFAKFSAYIKNS--RPEAN----EALERGLLKTLQKLDEYLNSPLPDEIDENS-MEDIKFSTRRF
LDGDEMTLADCNLLPKLHIVK--VVAKKYRNFDIP-KGMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYSDVA-------
------KRLTK---------------------------
>Rattus_norvegicus_CLIC4
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------MALSMPLNGLKEEDK-----
--------------------------------------------------------------------------------
---------------------------------EPLIELFVK----AGSD------------------GESIGNCPFSQR
LFMIL---WLKGVVFS--VTTVDLKRKPADLQNLAPGTHPPFITFNSEV--------KTDVNKIEEFLEEVLCPPKYLKL
SPKHPESNTAG--MDIFAKFSAYIKNS--RPEAN----EALERGLLKTLQKLDEYLNSPLPDEIDENS-MEDIKSSTRRF
LDGDEMTLADCNLLPKLHIVK--VVAKKYRNFDIP-KGMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYSDVA-------
------KRLTK---------------------------
>Loxodonta_africana_CLIC4
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------VLEQPLPAERKEAK-----
--------------------------------------------------------------------------------
---------------------------------ERLNTSVPQ----AGSD------------------GESIGNCPFSQR
LFMIL---WLKGVVFS--VTTVDLKRKPADLQNLAPGTHPPFITYNNEV--------RTDVNKIEEFLEEVLCPPKYLKL
SPKHPESNTAG--MDIFAKFSAYIKNS--RPEAN----EALERGLLKTLQKLDEYLNSPLPDEIDENS-MEDIKFSTRKF
LDGNEMTLADCNLLPKLHIVK--VVAKKYRNFDIP-KEMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYSDVA-------
------KRLTK---------------------------
>Pteropus_vampyrus_CLIC4
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------MALSMPLNGLKEEDK-----
--------------------------------------------------------------------------------
---------------------------------EPIIELFVK----AGSD------------------GESIGNCPFSQR
LFMIL---WLKGVVFS--VTTVDLKRKPVDLQNLAPGTHPPFITFNNEV--------KTDVNKIEEFLEEVLCPPKYLKL
SPKHPESNTAG--MDIFAKFSAYIKNS--RPEAN----EALERGLLKTLQKLDEYLNSPLPDEIDENS-MEDIKFSTRKF
LDGNEMTLADCNLLPKLHIVK--VVAKKYRNFDIP-KGMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYSDVA-------
------KRLTK---------------------------
>Pelodiscus_sinensis_CLIC4
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------MLMSCSLSQ----AGSD------------------GESIGNCPFSQR
LFMIL---WLKGVVFS--VTTVDLKRKPADLQNLAPGTHPPFITYNGEV--------KTDVNKIEEFLEDVLCPPKYLKL
SPRHPESNTAG--MDIFAKFSAFIKNS--RPEAN----EALERSLLKTLQKLDEYLNTPLPDEIDENS-MEDIAVSTRKF
LDGNEMTLADCNLLPKLHIVK--VVAKKYRNFDIP-KDMTGIWRYLTNAYSRDEFTNTCPGDKEIEIAYSDVA-------
------KRLTN---------------------------
>Takifugu_rubripes_CLIC4_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------MSLSVPQNGVK-ADN-----
--------------------------------------------------------------------------------
---------------------------------EPLIELFVK----AGSD------------------GESIGNCPFSQR
LFMIL---WLKGVVFN--VTTVDLKRKPADLQNLAPGTHPPFITFNGEV--------KTDVNKIEEFLEDVLCPPKYIKL
AARHPESNTAG--MDIFAKFSAFIKNP--RPDAN----EALERGLLKTLQKLDDYLRSPLPDEIDHNS-MEDIKVSRRNF
LDGDEMTLADCNLLPKLHIVK--VVAKKYRGFDIP-KEMTAVWKYLNNAYSREEFTNTCPSDKEIEIAYEDVA-------
------KRLVK---------------------------
>Tetraodon_nigroviridis_CLIC4_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------MSLSVPQNGVK-PDN-----
--------------------------------------------------------------------------------
---------------------------------EPVIELFVK----AGSD------------------GESIGNCPFSQR
LFMIL---WLKGVVFN--VTTVDLKRKPADLQNLAPGTHPPFITFNGEV--------KTDVNKIEEFLEDVLCPPKFIKL
AARHPESNTAG--MDIFAKFSAFIKNP--RPDAN----EALERGLLKTLQKLDDYLRSPLPDEIDHNS-IEDIKVSNRNF
LDGDEMTLADCNLLPKLHIVK--VVAKKYRGFNIP-KEMTAVWKYLNNAYSREEFTNTCPSDKEIEIAYEDVA-------
------KRLVK---------------------------
>Gasterosteus_aculeatus_CLIC4_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------MSLSVPQNGVK-ADD-----
--------------------------------------------------------------------------------
---------------------------------EPVIELFVK----AGSD------------------GESIGNCPFSQR
LFMIL---WLKGVVFN--VTTVDLKRKPADLQNLAPGTHPPFITFNGEV--------KTDVNKIEEFLEDVLCPPKYIKL
GVRHPESNTAG--MDIFAKFSAFIKNS--KPDGN----EALERGLLKTLQKLDEYLRSPLPDEIDHNS-IEDVKFSDRKF
LDGDEMTLADCNLLPKLHIVK--VVAKKYRGFDIP-KEMTAIWKYLNIAYTREEFTNTCPSDKEIEIAYGDVA-------
------KRLVK---------------------------
>Oryzias_latipes_CLIC4_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------MSLSVPQNGIK-ADN-----
--------------------------------------------------------------------------------
---------------------------------EPIIELFVK----AGSD------------------GESIGNCPFSQR
LFMIL---WLKGVVFN--VTTVDLKRKPADLQNLAPGTHPPFITFNGEV--------KTDVNKIEEFLEDVLCPPKFIKL
GARHPESNTAG--MDIFAKFSAFIKNS--KPDAN----EALERGLLKTLQKLDEYLRTPLPDEIDHNS-IEDVKVSGRKF
LDGDEMTLADCNLLPKLHIVK--VVARKYRGFDIP-KEMTAIWKYLNNAYTREEFINTCPSDKEIEIAYADVA-------
------KRLVK---------------------------
>Branchiostoma_floridae_CLIC4
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------MENGGDQEEPKIELFVK----AASD------------------GTSLGDCVFCQR
IFMIL---CLKKIKFS--VTTVDMTKKHLFKALPSLGTKIPFLMIDGEEP-------ITDVTEMANYLEKRLAPPMYPKL
EPNNPEAAMAG--TEIFQKFSKFIKNS--SQADE----ERLQRALYISLVQLNEFLIRRLPDEIDDDT--DENSPSERKF
LDGDQLTHPDCNLLPKLHHVR--VATKALKGFEIP-QDLTGLWRYLNSAYETEEFKKTLYPDEEIN-VYSDI--------
--------------------------------------
>Caenorhabditis_elegans_CLIC4
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------MAEAYQIQSNGDPQS----KPLLELYVK---ASGID------------------ARRIGADLFCQE
FWMELYA-LYEIGVARVEVKTVNVN--SEAFKKNFLGAQPPIMIEEEKELTY------TDNREIEGRIFHLAKEFNVPLF
EKDPSAEKRIE---NLYRNFKLFLRAK-VEFDKGK-----KEPSRVEDLPAQIKVHYNRVCEQLSNID--QLLSERKSRY
LLGNSMTEYDCELMPRLHHIR--IIGLSLLGFDIP-HNFTHLWAYILTAYRTAAFIESCPADQDIIHHYKEQMN------
LFTNQRETLQSPTKTHTIPEKVLSDIRVKGLAPDVNVH
>Homo_sapiens_CLIC5
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------MNDED
YS-TIYDTIQNERTYEVPDQPEENESPHYDDVHEYLRPENDLYATQLNTHEYDFVSVYTIKGEETSLASVQSEDRGYLLP
DEIYSELQEAHPGEPQEDRGISMEGLY------------------------SSTQDQQLCAAELQENGSVMKEDLPSPSS
FTIQHSKAFSTTKYS--CYSDAEGLEEKEGAHMNPEIYLFVK----AGID------------------GESIGNCPFSQR
LFMIL---WLKGVVFN--VTTVDLKRKPADLHNLAPGTHPPFLTFNGDV--------KTDVNKIEEFLEETLTPEKYPKL
AAKHRESNTAG--IDIFSKFSAYIKNT--KQQNN----AALERGLTKALKKLDDYLNTPLPEEIDANTCG-EDKGSRRKF
LDGDELTLADCNLLPKLHVVK--IVAKKYRNYDIP-AEMTGLWRYLKNAYARDEFTNTCAADSEIELAYADVA-------
------KRLSRS--------------------------
>Pan_troglodytes_CLIC5
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------MTDSATANGDDR-----
--------------------------------------------------------------------------------
---------------------------------DPEIELFVK----AGID------------------GESIGNCPFSQR
LFMIL---WLKGVVFN--VTTVDLKRKPADLHNLAPGTHPPFLTFNGDV--------KTDVNKIEEFLEETLTPEKYPKL
AAKHRESNTAG--IDIFSKFSAYIKNT--KQQNN----AALERGLTKALKKLDDYLNTPLPEEIDANTCG-EDKGSRRKF
LDGDELTLADCNLLPKLHVVK--IVAKKYRNYDIP-AEMTGLWRYLKNAYARDEFTNTCAADSEIELAYADVA-------
------KRLSRS--------------------------
>Macaca_mulatta_CLIC5
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------MNDED
YS-TIYDTIQNERTYEVPDQPEENESPHYDDVQEYLRPENDLYATQLNAYEYDFVSVYTINGEETSLASAQSEDRGYLLP
DEIYSELQEAQPGELQEDRGISMEGLY------------------------SPTQDQQPCPEGLQENGSVMKEDLPSPSS
FTIQHSKAFSISKYSSTCYSDAEGLEEKEGARMNPEICLFVK----AGID------------------GESIGNCPFSQR
LFMIL---WLKGVVFN--VTTVDLKRKPADLHNLAPGTHPPFLTFNGDV--------KTDVNKIEEFLEETLTPEKYPKL
AAKHRESNTAG--IDIFSKFSAYIKNT--KQQNN----AALERGLTKALKKLDDYLNTPLPEEIDASTCG-EDKGSRRKF
LDGDELTLADCNLLPKLHVVK--IVAKKYRNYDIP-AEMTGLWRYLKNAYARDEFTNTCAADSEIELAYADVA-------
------KRLSRS--------------------------
>Mus_musculus_CLIC5
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------MTDSATTNGDDR-----
--------------------------------------------------------------------------------
---------------------------------DPEIELFVK----AGID------------------GESIGNCPFSQR
LFMIL---WLKGVVFN--VTTVDLKRKPADLHNLAPGTHPPFLTFNGDV--------KTDVNKIEEFLEETLTPEKYPKL
AAKHRESNTAG--IDIFSKFSAYIKNT--KQQNN----AALERGLTKALRKLDDYLNSPLPEEIDTNTHG-DEKGSQRKF
LDGDELTLADCNLLPKLHVVK--IVAKKYRNYDIP-AEMTGLWRYLKNAYARDEFTNTCAADSEIELAYADVA-------
------RRLSRS--------------------------
>Oryctolagus_cuniculus_CLIC5
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------MDSATANGDDR-----
--------------------------------------------------------------------------------
---------------------------------DPEIELFVK----AGID------------------GESIGNCPFSQR
LFMIL---WLKGVVFN--VTTVDLKRKPADLHNLAPGTHPPFLTFNGDV--------KTDVNKIEEFLEETLTPEKYPKL
AAKHRESNTAG--IDIFSKFSAYIKNT--KQQNN----AALERGLTKALKKLDDYLNTPLPEEIDTNTRGDEDKGSRRKF
LDGDELTLADCNLLPKLHVVK--IVAKKYRNYDIP-AEMTGLWRYLKNAYARDEFTNTCAADAEIELAYADVA-------
------KRLSRS--------------------------
>Myotis_lucifugus_CLIC5
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------RVRYREIG------------------------SKSE-------------------------
-------------------------------------VFVLT----AGID------------------GESIGNCPFSQR
LFMIL---WLKGVVFN--VTTVDLKRKPADLHNLAPGTHPPFLTFNGDV--------KTDVNKIEEFLEETLTPEKYPRL
AAKHRESNTAG--IDIFSKFSAYIKNT--KQQNN----AALERGLNKALKKLDDYLSTPLPEEIDANTCGDDDKGSRRKF
LDGDELTLADCNLLPKLHVVK--IVAKKYRNYDFP-AEMTGLWRYLKNAYARDEFTNTCAADSEIELAYADVA-------
------KRLSR---------------------------
>Gallus_gallus_CLIC5
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------MSEP---------------SAANG--------DGK-------------
---------------------------------EPDIELFVK----AGID------------------GESIGNCPFSQR
LFMIL---WLKGVVFN--VTTVDLKRKPADLHNLAPGTHPPFLTFNGEV--------KTDVNKIEEFLEETLAPPKYPKL
AAKHRESNTAG--IDIFSKFSAYIKNT--KQQDN----AALERGLVKALKKLDDYLRTPLPEEIDANS-TEEEKVSKRKF
LDGDDLTLADCNLLPKLHVVK--IVAKKYRNFEFP-TEMTGLWRYLKNAYARDEFTNTCAADKEIEQAYADVA-------
------KRLSKS--------------------------
>Taeniopygia_guttata_CLIC5
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------MTDS---------------VAANG--------EGK-------------
---------------------------------DPEIELFVK----AGID------------------GESIGNCPFSQR
LFMIL---WLKGVVFN--VTTVDLKRKPADLHNLAPGTHPPFLTFNGEV--------KTDVNKIEEFLEEILAPPKYPKL
AAKHRESNTAG--IDIFSKFSAYIKNT--KQQDN----ATLERGLVKALKKLDDYLRTPLPEEIDADS-TEEEKVSKRKF
LDGDELTLADCNLLPKLHVVK--IVAKKYRNFEFP-AEMTGLWRYLKNAYTRDEFTNTCAADKEIEQAYADVA-------
------KRLSKS--------------------------
>Pelodiscus_sinensis_CLIC5
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------MEKGGFTTIYENVENTSIYEIPDSEEE
KVMNLYEQVHEDPVFPSSPTSPESMDISCLESLDHSCSNSVSSQQGADREDCSATSQQAADGDDSSASSQQGDDGDDGSA
SSQQGADGEDGSASSQQGAEDDQNLQ--EEMVMMSP---------------TQDDE--------HGERMGFENKIPSPTR
FSLRNSLGTSPSLPVSNRFPANNNFGEMDNFQEESDIFLFVK----AGID------------------GESIGNCPFSQR
LFMIL---WLKGVVFN--VTTVDLKRKPADLHNLAPGTHPPFLTFNGEV--------KTDINKIEEFLEEMLVPPKYPKL
AATHRESNAAG--IDIFSKFSAYIKNT--RQQDN----AGLERGLTKALKKLDNYLNTPLPEEIDANS-TEEEKVSKRKF
LDGDELTLADCNLLPKLHVVK--IVAKKYHNYEFP-TEMTGLWRYLKNAYARDEFTNTCAADKEIEQAYADVA-------
------KRLSKP--------------------------
>Takifugu_rubripes_CLIC5_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------QVGDRERR----------
----------------------GEDKD-----------------------------------------------------
----------------------------------PDIELFVK----AGND------------------GESIGNCPFSQR
LFMIL---WLKGVVFN--VTTVDLKRKPADLHNLAPGTHPPFVTFNGEV--------KTDINKIEEFLEEMLSPPKYPKL
AAKQRESNTAG--NDIFAKFSAYIKNT--KLDAN----SALEKGLTRALIKLDDYLNNPLPDEIDADS-LEEQKFSTRSF
LDGNELTLADCNLLPKLHIVK--VVAKKYRNYEIP-SEMSGVWRYLKNAYKRDEFTNTCAADAEIEMAYKDVV-------
------KRLAK---------------------------
>Tetraodon_nigroviridis_CLIC5_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------RLVAAEWR----------
----------------------GEDKD-----------------------------------------------------
----------------------------------PDIELFVK----AGSD------------------GESIGNCPFSQR
LFMIL---WLKGVVFN--VTTVDLRRKPADLHNLAPGTHPPFVTFNGEV--------KTDINKIEEFLEEMLGPPKYPKL
AAKHRESNTAG--NDIFAKFSAYIKNT--KPEAN----SGLEKGLTRALNKLDDYLNNPLPDEIDADS-MEEQKFSTRSF
LDGDQLTLADCNLLPKLHIVK--VVAKKYRNYDIP-SDMSGVWRYLKNAYKRDEFTNTCAADGEIETAYKDVA-------
------KRLAK---------------------------
>Homo_sapiens_CLIC6
--------------------------------------------------------------------------------
---MAEAAEPEGVAPGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAG---------GGGPDR-
---------GPEAEARGTRGAHGETEAEEG----APEGAEVPQGGEETSGAQQVEGASPGRGAQGEP---RGEAQREPED
SAAPERQEEAEQRPEV--PEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEGRVGDSVDAEG-PAGDSVDAEGPLGD
NIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSVDAEGRVGDSVEAG----DPAGDGVEAGVPAGDSVEAEGPAGDSMDAEG
PAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGELAWD-------AAEEAEVPGVKGSEEAAP--GDARADAG
EDR----------------VGDGPQQEPGE-DEERRERSPEGPREEEAAGGEEESPDSSPHGEASRG--AAEPEAQLSNH
LAEEGPAEGSGEAARVNGRREDGEASEPRALGQEHDITLFV----KAGYD------------------GESIGNCPFSQR
LFMIL---WLKGVIFN--VTTVDLKRKPADLQNLAPGTNPPFMTFDGEV--------KTDVNKIEEFLEEKLAPPRYPKL
GTQHPESNSAG--NDVFAKFSAFIKNT--KKDAN----EIHEKNLLKALRKLDNYLNSPLPDEIDAYS-TEDVTVSGRKF
LDGDELTLADCNLLPKLHIIK--IVAKKYRDFEFP-SEMTGIWRYLNNAYARDEFTNTCPADQEIEHAYSDVA-------
------KRMK----------------------------
>Pan_troglodytes_CLIC6
--------------------------------------------------------------------------------
---MAEAAEPEGVAPGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAG---------GGGPDR-
---------GPEAEARGTRGAHGETEAEEG----APEGAEVPQGGEETSGAQQVEGASPERGAEGEP---RGEAQREPED
SAAPERQEEAEQRPEA--PEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVDAEGPAGDSVDAEG-PAGDSVDAEGPAGD
SVDAECPAGDSVEAEG----------------------------------PAGDSAEAGVPAGDSVEAEGPAADSMDAEG
PAGRARRVSGEPQEAGDGSLSPQAEAIEVAAGESAGRSPGELTWD-------AAEEAEVPGGKGSEEAAP--GDARADAG
EDG----------------VGDGPQQESGE-DEDRREGSPEGPREEAAARGEEESPDSSPHGEASRG--AAEPEAQLSNH
LAEEGPAEGSDEAARVNGRREDGEASEQRALGQEHDITLFV----KVKLTALGCSRIAIKKYLRAGYDGESIGNCPFSQR
LFMIL---WLKGVIFN--VTTVDLKRKPADLQNLAPGTNPPFMTFDGEV--------KTDVNKIEEFLEEKLAPPRYPKL
GTQHPESNSAG--NDVFAKFSAFIKNT--KKDAN----EIHEKNLLKALRKLDNYLNSPLPDEIDAYS-TEDVTVSGRKF
LDGDELTLADCNLLPKLHIIK--IVAKKYRDFEFP-SEMTGIWRYLNNAYARDEFTNTCPADQEIEHAYSDVA-------
------KRMK----------------------------
>Macaca_mulatta_CLIC6
--------------------------------------------------------------------------------
---MAEAAEPEGGAPGPQGPLEVPAPLAERPGEPGSAGEEAEEPEGSEGAEEAPRGAAAVKEAG---------GGGPDR-
---------GPEAEAWGTRGAHREAEAEEG----APEVAQVPQGGEKTSSAQQVEGASPGRGAQGEP---RGEAQREPED
SAAPERQEEAEQRPEA--PEGSAPGAAGDSVDAEGPAGDNIEAEGRVGDSVEAEVPAGDSVDAEG-PAGDSVDAEGPAGD
SVDAEGPAGDSVDAEGLAGDSVEAEGPAGDSVDAEGPAGDSVEAG----DPVGDRVEAGDPVGDTVEAEGPAGDSMDAEG
PAGGTRRVSGEPQEGGDRSLPPQAEAIEVAAGESAGRSPGELAWD-------AAEETEVPGGKGSEEAGP--GDSRADAV
EDG----------------VGDGPQQESGE-EEERREQSPEGPSEEAAAGGEEEFPDSSPQGEASRC--AAEPEAQLSNH
LAEEGPAEGGDEAVRMNGRREDGEASEERALGQEHDITLFV----KAGYD------------------GESIGNCPFSQR
LFMIL---WLKGVIFN--VTTVDLKRKPADLQNLAPGTNPPFMTFDGEV--------KTDVNKIEEFLEEKLAPPRYPKL
GTQHPESNSAG--NDVFAKFSAFIKNT--KKDAN----EIYEKNLLKALRKLDNYLNSPLPDEIDAYS-TEDATVSGRKF
LDGDELTLADCNLLPKLHIIK--IVAKKYRDFEFP-SEMTGIWRYLNNAYARDEFTNTCPADQEIEHAYSDVA-------
------KRMK----------------------------
>Mus_musculus_CLIC6
--------------------------------------------------------------------------------
---MAEATEPKEVAPGSQGQPEGAT--IEGPGEPGAAD--LEGREASEEAAEAPRDLGAGVEARASGKEEGGCGQDEGTG
GAQAQDPRTGPEAETPGASGAPGEAEAAER----DPEGA-IPQGAEEAPSAQQVQGMSSGLDSQGEAPEVPGDSRREPED
PTASEAGEEAESGQEA--QGGGALGLQIN---------------------------------------------------
-----------------------------------------------------------------PEVQGLAGDNMDTEA
PAGGPLGSESEPQGGGESSPQPQDEAIEIVTTEIGGNESGELAGA---SAADAAGEGETLGKDGSEEAAS--EDARVDAH
ENG-----------------DQGKLQEETGEEEARPEPELKGPCEGAIQEKPPDGSLDGEEAKSTEH--EEESQAELSNH
LAEEPSVQGGEELGRVNGRRENGPALEEGDPGQEHDITLFV----KAGYD------------------GESIGNCPFSQR
LFMIL---WLKGVIFN--VTTVDLKRKPADLQNLAPGTNPPFMTFDGEV--------KTDVNKIEEFLEEKLVPPRYPKL
GTQHPESNSAG--NDVFAKFSAFIKNT--KKDAN----EIYEKNLLRALKKLDSYLNSPLPDEIDADS-SEDVTVSQRKF
LDGDELTLADCNLLPKLHIIK--IVAKKYRDFEFP-SEMTGIWRYLNNAYARDEFTNTCPADREIEHAYSDAA-------
------KRMK----------------------------
>Rattus_norvegicus_CLIC6
--------------------------------------------------------------------------------
---MAEATEPKEVSSGSQGQPEGAV--IEGPGEPGAAD--LEGREASEGAAEAPRDLGEGAEAMASGKEEGGCGQDGEIG
EVQAQDPRPGPGTETPGTSGAPGEAEAAEC----DSEGALIPQGAEEAPSAQQVQGTSSGLDAQGEAPEVPEDARREPED
PKASEAGEEAESGQEA--LGGSAPESQIN---------------------------------------------------
-----------------------------------------------------------------PEVQGPVGDNMDTEA
PAGEPQGSEGEPQGGGESSPQPQDEAIEIAAAEVGGHEPGELAGA---SAADAKGEGETLRKDGFEEAAP--EEARVDSG
ENGFEEAAPEEARVDSGENRDQGRLQEETGEEEARPESGLKGPCEEAIQEKAPDGSLDGEEAKSTGH--EE-SQVELSNH
LAEETSAQGGEELGRVNGRRENGPASEEGDLGQEHDITLFV----KAGSD------------------GESIGNCPFSQR
LFMIL---WLKGVIFN--VTTVDLKRKPADLQNLAPGTNPPFMTFDGEV--------KTDVNKIEEFLEEKLVPPRYPKL
GTQHPESNSAG--NDVFAKFSAFIKNT--KKDAN----DIYEKNLLRALKKLDSYLNSPLPDEIDAYS-TEDVTVSQRKF
LDGDELTLADCNLLPKLHIIK--IVAKKYRGFEFP-SEMTGIWRYLNNAYARDEFTNTCPADQEIEHAYSDAA-------
------KRMK----------------------------
>Loxodonta_africana_CLIC6
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------AGYD------------------GESIGNCPFSQR
LFMIL---WLKGVIFN--VTTVDLKRKPADLQNLAPGANPPFMTFDGEV--------KTDVNKIEEFLEEKLAPPRYPKL
GTQHPESNSAG--NDVFAKFSAFIKNT--KKDAN----DIYEKNLLRALKKLDSYLSSPLPDEIDAYS-TEDVPVSGRKF
LDGDELTLADCNLLPKLHVIK--IVAKRYRDFEFP-PEMSGLWRYLNNAYARDEFANTCPADQEIVHAYSDVA-------
------KRMNK---------------------------
>Pteropus_vampyrus_CLIC6
--------------------------------------------------------------------------------
---MAEATEPEGGAPGPQGPPEGPAPLADRPGEAGAAGLAANGEQAGERAAEARRGVAAGTER-----EGDELAPGTDR-
---------DPGTEKPGSSGAQSEPQAEEG----APQGAEAPQGGEEKGSAQQVEEASVGCGAQGEE------AQGERGD
PAAPKAEEEAERGPEE--PGSSARGAPRTSVDVGGLRGSSMEAEG-----------------------------------
--------------------------------------------------------------------------------
SEGAAPRAEEVPRDGGDRSSQSHVQATEAAAAETADCTPGELCGEPQGAAGGAAEEAGAPGEEDSEEASP--GDAKADAR
EDG----------------AGG---PQEEEAEEERRERGPEGPGEEAPPDGSAPGGDAQTR--------AAEPEGQLSNH
LAAEGSAEDAAEAARVNGRGEDGEASEEGAPRREHDITLFVKVTHAAGYD------------------GESIGNCPFSQR
LFMIL---WLKGVIFN--VTTVDLKRKPADLQNLAPGTNPPFMTFDGEV--------QTDVNKIEEFLEEKLAPPRYPKL
GTQYPESNSAG--NDVFAKFSAFIKNT--KKDVN----EXYEKNLLKALKKLDNYLNSPLPDEVDVYS-TEEVAVSGRKF
LDGDELTLADCNLLPKLHIIK--IVAKRYRDFEFP-PDMTGIWRYLHNAYARDEFTNTCPADQEIEHAYSDVA-------
------KRMK----------------------------
>Gallus_gallus_CLIC6
--------------------------------------------------------------------------------
---------------------------