>Homo_sapiens_SH2D3A
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--------------------------------------------MQVP-QDGED----------LAGQPWYHGLLSR---
QKAEALLQQNGDFLVRASGS----RGGNPVISCRWRGS-ALHFEVFRVALRPR---PGRPT-ALFQLEDEQFPSIPALVH
SYMTGRRPLSQATGAVVSRPVTWQGP----------LRRS-------FSEDTLMDGPA----------------------
-------------RIEPLRARK--------------------------WSNSQP--------------ADLAHMGRSR--
------------------------------EDPAGMEAS----------------TMPISALPRTSSDPVLLKAPAPLGT
-----VADSLRASDGQLQAKAPTKPPRTPSFELP-------------------DASERPPTYCELVP-------------
------------RVPSVQGT-------------SPSQSCPE---------------------PEAPWWEAEEDEEEE---
----NRCFTRPQAEIS-FCPHD-APSCLLGP-QNRPLEPQVLHTLRGLFLEHHPGSTALHLLLVDCQATGLLG-VTRDQR
GNM---------GVSSGLELLTLPHGHHLRLELLERHQTLALAGALAVLGCSGPLEERAAALRGLVELALALRPGAAGDL
PGLAAVMGALLMPQVSRLEHTWRQLRRSHTEAALAFEQELKPLMRALDEGAG---PCDPGEVALPHVAPMVRLLEG----
----------------------EEVAGPLDESCERLLRTLHGAR-HMVRDAPKFRKVAAQRLRG-F-RPNPELREALTTG
FVRRLLWGSRGAGAPRAERFEKFQRVLGVLSQRLEPDR------------------------------------------
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------------------------------------------
>Pan_troglodytes_SH2D3A
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--------------------------------------------MQVP-QDGED----------LAGQPWYHGLLSR---
QKAEALLQQDGDFLVRASGS----RGGNPVISCCWRGS-ALHFEVFRVALRPR---PGRPT-ALFQLEDEQFPSIPALVH
SYMTGRRPLSQATGAVVSRPVTWQGP----------LRRS-------FSEDTLMDGPA----------------------
-------------RIEPLRARK--------------------------WSNSQP--------------ADLAHMGRSR--
------------------------------EDPPGMEAS----------------TMPISALPRTSSDPVLLKAPAPLGT
-----VADSLRASDGQLQAKAPTKPPRTPSFELP-------------------DASERPPTYCELVP-------------
------------RVPSVQGT-------------SPSQSCPE---------------------PEAPWWEAEEDEEEE---
----NRCFTRPQAEIS-FCPHD-APSCLLGP-QNRPLEPQVLHTLRGLFLEHHPGSTALHLLLVDCQATGLLG-VTRDQR
GNM---------GVSSGLELLTLPHGHHLRLELLERHQTLALAGALAVLGCSGPLEERAAALRGLVELALALRPGAAGDL
PGLAAVMGALLMPQVSRLEHTWRQLRRSHTEAALAFEQELKPLMRALDEGAG---PCDPGEVALPHVAPMVRLLEG----
----------------------EEVAGPLDESCERLLRTLHGAR-HMVRDAPKFRKVAAQRLRG-F-RPNPELREALTTG
FVRRLLWGSRGAGAPRAERFEKFQRVLGVLSQRLEPDR------------------------------------------
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>Macaca_mulatta_SH2D3A
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------------------------------------EAF----------------ATPVSALPRTGSDPVLLKAPAPLGT
-----VANSLRASDGQLQAKAPAKPPRTPSFELP-------------------DASERPPTYCELVP-------------
------------RVPCVQGT-------------SLSQSCPE---------------------PEAPWWEAEEDEEEE---
----NRCFTRPQAEIS-FCPPD-TPSCLLGP-QNRPLEPQVLHTLRGLFLEHHPGSTALHLLLVDCQATGLLG-VTRVQR
DNM---------GVSSGLELLTLPHGCRLRLELLERHETLALAGALAVLGCSGPLEERAAALRGLVELALALRPGAAGDL
PGLAAVMGALLMPQVSRLEHTWRQLRRSHTEAALAFEQELKPLMRALDEGVG---PCDPGEVALPHVAPTVRLLEG----
----------------------EEVAGPLDESCERLLRTLHGAR-HMARDAPKFRKVAAQRLRG-F-RPNPELREALTTG
FLRRLLWGSRGAGAPRAERFEKFQRVLGVLSQRLEPDS------------------------------------------
--------------------------------------------------------------------------------
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------------------------------------------
>Callithrix_jacchus_SH2D3A
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--------------------------------------------MQVP-QDGED----------LAGQPWYHGPLSR---
QKAEALQQ-DGDFLVRASGS----RGGHPVISCRWRGS-ALHFEVFRVALRPR---PGRPT-ALFQLEDEQFPSMPALVH
SYLTGKRPLSQATGAVVSRPVTRPGP----------LRRS-------FSEDTLMDGPA----------------------
-------------RTEPLRVRK--------------------------WSSSQP--------------ADLAHIGRSR--
------------------------------EDPPGMGAS----------------TMPVSALLRSGSEPVLLKAPASLGT
-----INNSLRGSDGQLQAKAPTKPPRTPSLELP-------------------DVPERPPTYCELVP-------------
------------RVPSVQGT-------------SPSQSRQE---------------------TEVPWWEAEEDEEEE---
----NRCFTRPQAEIA-FCPPD-APSCLLGP-QNRPLEPQVLRTLRDLFLEHHPGSTALHLLLVDCQATGLLG-VTRDQR
GNM---------GVSSGLELLTLPHGHRLRSELLERHETLTLAGALAVLGCSGPLEERAAAVRGLVELALALRPGAAGDL
PGLAAVMGALLMPQVSRLEHTWRHLRRSHTEAALAFEQELKPLMRALDEGAG---PCDPGEVALPHVAPVVRLLEGG---
----------------------EEVAGPLEESGERLLRTLHGAR-QMARLAPKFRKVAAQRLRG-F-RPNPELSEALTTG
FLRRLLWGSRGAGAPHAERFEKFQRVLGVLSLRLEPDR------------------------------------------
--------------------------------------------------------------------------------
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------------------------------------------
>Canis_familiaris_SH2D3A
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--------------------------------------------MQVP-QDGED----------FASQPWYHGPLSR---
QKAEALLQQDGDFLVRASRS----RGGHPVISCRWQGS-ALHFEVLRVALRPR---PGRPT-ALFQLEDERFPSLPSLVL
SYVTGQRPLSQATGAVASRPVIRQGP----------IRRS-------FSEDTLLESPA----------------------
-------------RIELPRARK--------------------------RSDSQP--------------AGLEHMGLSG--
------------------------------EDHSGPGAS----------------PVPTCALPRMGSDPVLLKTPASLGS
-----VVDGLRASDGQLHAKAPNKPPRTPSLVLH-------------------DASGRPPTYCELVP-------------
------------RVPSAQET-------------PTGHSGPE---------------------TEASWWEANEEEEEE---
----DRSFARPKAEVF-FCPPN-NLFCLLGP-QNRPLEPKVLSTLRDLFLEHHPGSTALHLLLVDCQATGLLG-VTKAQR
GAM---------GVTSGLELLTLPHGHRLRLELLERHEALALAGALAVLGCSGPLEERAATLRGLVELALALRPGAAGDL
PGLAAVMGALLMPQVSRLERTWRQLRRSHTQAALAFEQELKPLMRALDEGAG---PCAPGEVALPHVVPAVRLLEG----
----------------------QELPGPLDESCERLLRTLHRAR-LVARDAPQFREAAARRLRG-F-QPNPQLREALTTG
FVQRLLWGSQGVGAPHATRLEKFQRVLSALSQRLEPDV------------------------------------------
--------------------------------------------------------------------------------
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------------------------------------------
>Felis_catus_SH2D3A
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--------------------------------------------MQVP-QDGED----------FASQPWYHGPLSR---
QKAEALLQQDGDFLVRASGS----RGGHPVISCRWQGS-ALHFEVLRVALRPR---PGRPT-ALFQLEDERFPSLTSLVL
SYVTGQRPLSQATGAVASRPVIRQGP----------IRRS-------FSEDTLRGSPA----------------------
-------------LTELPRTRK--------------------------WSDSQP--------------AGLEHMGRSR--
------------------------------EDHCGPEAS----------------AMPLCALPRTGSDPVLLKTPAPLGS
-----VADSLRASDGQLHAKAPTKPPRTPSLVLR-------------------DASGRPPTYCELVP-------------
------------RVPSAQGT-------------PPGHSSPE---------------------TEAPWWEAEEEEEEE---
----SRSFARPQAEVS-FCPPN-NPSCLLGP-QNRPLEPRVLSTLRGLFLEHHPGSTALHLLLVDCQATGLLG-VTKAQR
GAM---------GVASGLELLTLPHGHRLRLELLERHEALALAGALAVLGCAGPLEERAATLRGLVELALALGPGAAGDL
PGLAAVMGALLMPQVSRLERTWRQLRRSHTEAALAFEQELKPLMRALDEGAG---PCDPGEVALPHVVPAVRLLEG----
----------------------EELPGPLDESCERLLRTLHRAR-QMAQDAPKFREAAARRLRG-F-HPNPQLREALTTG
FVQRLLWGSRGVGAPQAARLEKFQRVLSVLSQRLEPDG------------------------------------------
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------------------------------------------
>Bos_taurus_SH2D3A
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--------------------------------------------MQVP-QDGED----------FVGQPWYHGPLSR---
QKAEDLLQQDGDFLVRASKS----RGGHPVISCRWRGS-ALHFEVLRVALRPR---PGRPT-ALFQLEDERFPSLPALVR
SYVIGQRPLSQATGAVASRPVPRQGL----------IRRS-------FSEDTLPDDPA----------------------
-------------RTEPLRDRK--------------------------RSDSQP--------------AGLEHMWRSP--
------------------------------EDPPGPGAS----------------TVPASGLPRTGSDPVILKTPVPLGS
-----VADSLRASDGQLHAKAPTKPPRTPSLLLP-------------------DASGRPPTYCELVP-------------
------------RVLRFQGP-------------PPGHSCPE---------------------SEVPWWEAEEEKEE----
----DRCFARPQAEVS-FCLPD-TPSCLLGS-QNRPLEPEVLHTLRGLFLEHHPGSTALHLLLVDCQATGVLG-VTKAQR
GAM---------GVASGLELLTLPHGHRLRLELLERLETLALAGALAVLGCAGPLEERAAALRGLVELAVALRPGAVGDL
PGLAAVMGALLMPQVSRLERTWRHLRRSHTEAALAFEQELKPLMRSLNEGAG---PSDPGEVALPHVAPAARLLEG----
----------------------EELPGPLDESCERLLRTLHRAR-QTARDAPRFREAVARRLRG----------------
--------------------------------------------------------------------------------
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>Pteropus_vampyrus_SH2D3A
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--------------------------------------------MQVP-QDGED----------FASQPWYHGPLSR---
QKAEALLRQDGDFLVRASES----HGGHPVISCRWQGL-ALHFEVLCVALRPR---PGRPA-ALFQLEDERFPSLHALVH
SYVSGQRPLTQATGAVASRPVTRQEP----------IRCS-------FSEDTLLDSPA----------------------
-------------RVKLLRGRK--------------------------WSDSQP--------------AGLELVGQSR--
------------------------------EGHSGPGAS----------------AVPTFALRRMGSDPVLLKTSDPLGS
-----IADSLWASDGQLHTKMPTKPPRTPPLVLP-------------------DASGRPPTYCELVL-------------
------------RVSSARGT-------------PSGHSCPE---------------------PETPWWETQEEVEDE---
-----RCFARPQAQVS-FCPAD-NPSSLLGP-QNRPLEPKVLHILRGLFLEHHPASTACHLLLADCQATGLLG-VTKAQR
DAM---------GVASGLELLTLPHGHCLRSELLERHEALVLAGALAVLGCSGPLEERAAALRGLVELALELRPGAAGDL
PGLAAVMGALLMPQVSRLERTWRQLRRSHTEAALAFEQELKPLMRALDEGAG---PCDPGEVALPHVAPAVRLLEG----
----------------------EEILGPLDESCEQLL--------HVARDAPKFREAAARRLRG-F-RPNPELSEALTTG
FMRRLLWGSRGEGAPRAARLEKFQLVLSVLSHRLEPDH------------------------------------------
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>Takifugu_rubripes_SH2D3A_a
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------------------------MDA-----------LKKELEEELK-LSSED----------LKSHAWYHGPLGR---
EAGEALLERDGDFLVRDSSS----APGDYVLTCFWMNG-PMHFKIIR-VVLRP---KQGYSRELFQFEEDRFDNVPALIR
FHVGSRRPISQASSAVIFHPITRTLPLRVIREQQAG------------AGSGKQAK----SSKRR-------SLSTAH--
--------------ADMLQIINP-------------------------LLRSG------------SQPANLENVGRRP--
-------------------------SLQSAQSDSNIRTGTILTTVTR---AQDPGPAPISPVFRTGSEPLLSP--QHTRP
SLPGV-GVTLQGSDGQLHPRAPPKPLRISAVFPN-----------AVIPPPIQRDEDPSSFYDELVVQYHSLCLSK-TK-
--IPQAKQKGHVDRLRAEEKWQSRAR------LTETSFGFLEAS--SQL----------------PVIPQKKMADKV---
---EDCHFQKPQVETGSCFQLDRFDSLLLPQ-NNRPLEPSVLLALKELFNRSNANTTALHMLSVDCQVARITGVTEEQKT
-LM---------GVESGLELVTLPHGQQLRQDLLERHHLISLGVAVDILGCTGTVSQRAAVLHKIILLAQALKE-HTHNL
YSFSAVMKALEMHQITRLEMTWRALRQNHTEMAVLFEKTLKPFMKLLNEGND---SVVDGPVAVPHLVPLLMAM------
--------------------EGDDPVENSERGCQLLYNILQSAR-NAAVRAQEYQEHAHSLLTG-W-VPVPELLEAFQTE
FALRLLWGQSGAAGDKRERYEKFDKVLSVLSNKLEPVEHNPDTC------------------------------------
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>Tetraodon_nigroviridis_SH2D3A_a
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--------------------------------------LKKELEEELK-LSSED----------LSSHAWYHGPLRR---
EAAEALLERNGDFLVRDSSS----TPRDYVLTCFWMNM-PMHFKIIR-VVLRP---KKGYSRELFQFEEDRFDNIPALIR
LYVGGRRPISQASGAVISHPITRTLPLRVIREQQAVPDSK-------GAGSDKEAK----SSKRR-------SLST----
--------------ADTLQVINP-------------------------LLRSGEACRNAYKYRSGSQPANLENVGRRP--
-------------------------SLQSAQSDSNIRTGT--PQITR---AEEPGPVPMSPVFRTGSEPMLSP--RHTRP
SLPGG-GVTLRGSDGQLHPRAPPKPLRVSAVFPN-----------AVIPPPLQRKEDPSSFYDELVVQYHSLCLYK-QRG
LPVPQARHKSHVDRLRAEEKWQSRAR------LTETSFGFLEAS--SQP----------------PLIPQK-TEQKV---
---EDWHFQKPHVELESCFQLDRFDSLLLPQ-NNRPLEPSVLLVLKELFNRSNANATALHMLSVDCQVVRITQVTEEQKT
-IM---------GVESGLELITLPHGRQLRLDLLERHHLLALGVAVDILGCTGTVSQRAAVLHKIILLAQALKE-HAHDL
YSFSAVMKALEMPQVARLEMTWRALRQNHTEMAVLFEKTLKPFMNLLNEGDN---AAFDGPVAVPHLVPLLMAM------
--------------------EGDDPVENSERGCQLLYNILQCAR-NTAVHAHDYQQHANSLLTG-W-VPVPELLEVFRTE
FALRLLWGQSGAAGDKRERYEKFDKVLTVLSNKLEPVEIRTTQA------------------------------------
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------------------------------------------
>Drosophila_melanogaster_SH2D3A
----------------------------------------------------------------------MGNTQARQLE
NRQVPNRRSSILWNFRYSNTVRRREDLAVMVHNS-RMSISEWLDLLELQQYEGNLQEFSTVDDVVDITDKELKQFGVRG-
AHRQRMVNSLLGVRAKRRQSMNLEAMSSA---------------------------------------------------
--------------PRAVPRRKNSCPLVYLGENPQDMAGSGDSGPGVITTKSGKVLKQLTFDETSTIYEELRPRSKCNS-
PHWAIEDSRMEG-YGSSNATTPLATAQPSPSEQQEAIALKKALEWELS-LDARE----------LRSHAWYHGALPR---
QRAEEIVQREGDFLVRDCAS----QPDNYVLSCRSKAA-VLHFVLNK-LVLQP---ETVYERVQYQFEEDAFDTVPDLIT
FYVGSGKPISSASGALIQFPCNRTYPLSFYGHKIVGNQLHTQMLAGLRGLSPLNSPMGSNGAVGAGMNATFRFEPQQQQQ
QQLSPMAGSPASPHCSPPRARREVPP-------------------PPRLPCKKQQRSQSLTPAQAMLVSNINKLQEQQL-
------------------------QMQELENGNGNGIMR-----FQTIARCNPTSEQHLESKFTTHSLPRPN--TSAAHA
LRQQAVARISSLARN--CSLDSPSDSRPPSPPPK-------------------PRKEPMAAVLAYQASGSDSG-------
----NGSGD-----SALGDACEASVQR---GVIIKNPRFMTTS---------------------VSNGTLKSFTEFDVLA
AEEELFTMAIEEVKTASKFDFENFVTLLLPSVENKPLDGDALNTFKMMLLETGPKLLAEHITRIDIALFLEEPSNEEDYY
------------LSCSGLELLTLPHGKVFREDIIERTQCIKLMVAVTILTCQTDLDR-AQLLSKWIQIAVETKT-ALGNL
FGFCAIMLGLCMQQIQKLDQAWHILRQQYTDSAFTFEAKLRPTLSIMNEASN----PQAPNTTVPHVLLYALLIDRPVMD
IINHSNIDDR---PALYHTCIAPWESKADDFGMTINFQHLDASR-GFLKNLELYRKNAKIILEDASPRLDELLADAFRTE
FHVKFLWGSSGATAKAEDRHNKLEKVLTLMADKFCMMAEQ----------------------------------------
--------------------------------------------------------------------------------
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------------------------------------------
>Homo_sapiens_BCAR3
------------------------------------------------------------------------MAAGKFAS
LPRNM--PV--NHQFPLASSMDLLSSRSPL-AEHRPD-----------AYQDVSIHGTLPRKKKGPPPIRSCDDFSHMGT
LPHSKSPRQNSPVTQDGIQESPW---------------------------------------------------------
----------------------------------------------------------------------QDRHGETFTF
RDPHLLDPTV---EYVKFSKERHIMD------RTPEK-LKKELEEELL-LSSED----------LRSHAWYHGRIPR---
QVSENLVQRDGDFLVRDSLS----SPGNFVLTCQWKNL-AQHFKINR-TVLRL---SEAYSRVQYQFEMESFDSIPGLVR
CYVGNRRPISQQSGAIIFQPINRTVPLRCLEEHYGTS-PG-------QAREGSLTKGRPDVAKRL-------SLTMGG--
-----------VQAREQNLPRGN-------------------------LLRNKEK--------SGSQPACLDHMQDRRA-
------------------------LSLKAHQSESYLPIGCKLPPQSS---GVDTSPCPNSPVFRTGSEPALSPAVVRRVS
SDARA-GEALRGSDSQLCPKPPPKPCKVPFLKV---------------PSSPSAWLNSEANYCELNPAFATGC----GRG
AKLPSCAQGSHTELLTAKQNEAPGPR------NSGVNYLILDD-DDRER----------------PWEPAAAQMEKG---
-QWDKGEFVTPLLETVSSFRPNEFESKFLPP-ENKPLETAMLKRAKELFTNNDPKVIAQHVLSMDCRVARILGVSEEMRR
-NM---------GVSSGLELITLPHGHQLRLDIIERHNTMAIGIAVDILGCTGTLEDRAATLSKIIQVAVELKD-SMGDL
YSFSALMKALEMPQITRLEKTWTALRHQYTQTAILYEKQLKPFSKLLHEGRE-STCVPPNNVSVPLLMPLVTLMERQ---
----------------AVTFEGTDMWEKNDQSCEIMLNHLATAR-FMAEAADSYRMNAERILAG-F-QPDEEMNEICKTE
FQMRLLWGSKGAQVNQTERYEKFNQILTALSRKLEPPPVKQAEL------------------------------------
--------------------------------------------------------------------------------
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------------------------------------------
>Pan_troglodytes_BCAR3
------------------------------------------------------------------------MAAGKFAS
LPRNM--PV--NHQFPLASSMDLLSSRSPL-AEHHPD-----------AYQDVSIHGTLPRKKKGPPPIRSCDDFSHMGT
LPHSKSPRQNSPVTQDGIQESPW---------------------------------------------------------
----------------------------------------------------------------------QDRHGETFTF
RDPHLLDPTV---EYVKFSKERHIMD------RTPEK-LKKELEEELL-LSSED----------LRSHAWYHGRIPR---
QVSENLVQRDGDFLVRDSLS----SPGNFVLTCQWKNL-AQHFKISR-TVLRL---SEAYSRVQYQFEMESFDSIPGLVR
CYVGNRRPISQQSGAIIFQPINRTVPLRCLEERYGTS-PG-------QAREGSLTEGRPDVAKRL-------SLTMGG--
-----------VQAREQNLPRGN-------------------------LLRNKEK--------SGSQPACLDHMQDRRA-
------------------------LSLKAHQSESYLPIGCKLPPQSS---GVDTSPCPNSPVFRTGSEPALSPAVVRRVS
SDARA-GEALRGSDSQLCPKPPPKPCKVPFLKV---------------PSSPSAWLNSEANYCELNPAFATGC----GRG
AKLPSCAQGSHTELLTAKQNGAPGPR------NSGVNYLILDD-DDRER----------------PWEPAAAQMEKG---
-QWDKGEFVTPLLETVSSFRPNEFESKFLPP-ENKPLETAMLKRAKELFTNNDPKVIAQHVLSMDCRVARILEVSEEMRR
-NM---------GVSSGLELITLPHGHQLRLDIIERHNTMAIGIAVDILGCTGTLEDRAATLSKIIQVAVELKD-SMGDL
YSFSALMKALEMPQITRLEKTWTALRHQYTQTAILYEKQLKPFSKLLHEGRE-STCVPPNNVSVPLLMPLVTLMERQ---
----------------AVTFEGTDMWEKNDQSCEIMLNHLATAR-FMAEAADSYRMNAERILAG-F-QPDEEMNEICKTE
FQMRLLWGSKGAQVNQTDRYEKFNQILTALSRKLEPPPAKQAEL------------------------------------
--------------------------------------------------------------------------------
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------------------------------------------
>Macaca_mulatta_BCAR3
------------------------------------------------------------------------MAAGKFAS
LPRNM--PV--NHQFPLASSMDLLSSKSPL-TEHRPD-----------AYQDVSIHGTLPRKKKGPPPIRSCDDFSHMGT
LPHSKSPRQNSPVTQDSIQESPW---------------------------------------------------------
----------------------------------------------------------------------QDRHCETFTF
RDPHLLDPTL---EYVKFSKERHIMD------RTPEK-LKKELEEELL-LSSED----------LRSHAWYHGRIPR---
QVSENLVQRDGDFLVRDSLS----SPGNFVLTCQWKNL-AQHFKINR-TVLRL---SEAYSRVQYQFEMESFDSIPGLVR
CYVGNRRPISQQSGAIIFQPINRTVPLRCLEERYGIS-PG-------QAREGSLTEGRPDVTKRL-------SLTMGG--
-----------VQAREQNLPRGN-------------------------LLRNKEK--------SGSQPACLDHMQDRRA-
------------------------LSLKAHQSESYLPIGCKLPPQSS---GVDTSPCPNSPVFRTGSEPALSPAVVRRVS
SDARA-GEALRGSDSQLCPKPPPKPCKVPFLKA---------------PSSPSAWLNSEANYCELNPAFAT------GRG
AKLPLCAQGSPTELLTAKQNGALGPR------NSGINYLILDD-DDRER----------------PWEPAAAQTEKG---
-QWDKGEFVAPLLETVSSFRPNDFESKFLPP-ENKPLETAMLKRAKELFTNNDPKVIAQHILSMDCRVARILEVSEEMRR
-NM---------GVSSGLELITLPHGHQLRLDIIERHSTMAIGIAVYILGCTGTLEDRAATLSKVIQVAVELKD-SMGDL
YSFSALMKALEMPQITRLEKTWTALRHQYTQTAILYEKQLKPFSKILHEGRE-STCVPPNNVSVPLLMPLVTLMERQ---
----------------AVIFEGTDMWEKNDQSCEIMLNHLATAR-LMAEATDSYRINAERILAG-F-QPDEEMNEICKTE
FQMRLLWGSKGAQVNQAERYEKFNQILTALSRKLEPPPVKQAEL------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------
>Callithrix_jacchus_BCAR3
------------------------------------------------------------------------MAAGKFAS
LPRNM--PV--NHQFPLASSMDLLSSKSSL-TEHRTD-----------AYQDVSIHSTLPRKKKGPPPIRSCDDFSHMGT
LPHSKSPRQNSPLTQDGIQESPR---------------------------------------------------------
----------------------------------------------------------------------QDRQGETFTF
RDPHLLDPTL---EYVKFSKERHMMD------RTPER-LKKELEEELL-LSSED----------LRSHAWYHGRIPR---
QVSENLVQRDGDFLVRDSLS----SPGNFVLTCQWKNL-AQHFKINR-TVLRL---SEAYSRVQYQFEMESFDSIPGLVR
CYVGNRRPISQHSGAIIFQPINRTVPLRCLEERYGTS-SG-------RAQEGSLTEGRPDVAKRL-------SLTMGG--
-----------VQTREQNLPRGN-------------------------LLRNKEK--------SGSQPACLDHMQDRRA-
------------------------LSLKAHQSESYLPIGCKLPPQSS---GVDTSPCPNSPVFRTGSEPALSPAVVRRVS
SDARA-GEALRGSDSQLCPKPPPKPCKVPLLKA---------------PSSPSAWLNSEANYCELNPAFATGC----SRA
AKLPLCAQGSRTELLTARQNGVPGPR------NSGINYLILDG-DDRER----------------PWEPVATQMEEG---
-QWDKGKFVTPLLETVSSFRPNDFESKLLPP-ENKPLETAMLKRAKEVFTNSNPKIIAQHILSMDCKVARILEVSEEMKR
-NM---------GVSSGLELITLPHGHQLRLDIIERHNTMAMGIAVDILGCTSTLDERAATLSKIIQVAVELKD-SMGDL
YSFSALMKALEMPQITRLEKMWTALRHQYTQTAILYEKQLKPFSKILHEGRE-STCVPPSNVSVPLLMPLVTLMERQ---
----------------AVTFEGTDMWEKNDQSCEIMLNHLATAR-FMAQTADSYRMNAEMNLAG-F-QPDEEMNEICKTE
FQMRLLWGSKGAQVNQTERYEKFNQILTALSRKLEPPPVKQAEL------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------
>Mus_musculus_BCAR3
------------------------------------------------------------------------MAAGKFAS
LPRNM--PV--NHQFPLASSMDLLSSKSPL-AERRTD-----------AYQDVSIHGTLPRKKKGPPSIRSCDNAG----
--HSKSPRQSSPLTQDIIQENPL---------------------------------------------------------
----------------------------------------------------------------------QDRKGENFIF
RDPYLLDPTL---EYVKFSKERHIMD------RTPER-LKKELEEELL-LSSED----------LRSHAWYHGRIPR---
QVSENLVQRDGDFLVRDSLS----SPGNFVLTCQWKNL-AQHFKINR-TVLRL---SEAYSRVQYQFEMESFDSIPGLVR
CYVGNRRPISQQSGAIIFQPINRTVPLWCLEERYGTS-PG-------RGREGSLAEGRPDVVKRL-------SLTTGSS-
-----------IQAREHSLPRGN-------------------------LLRNKEK--------SGSQPACLDHVQDRKA-
------------------------LTLKAHQSESHLPIGCKLPPQSP---SMDTSPCPSSPVFRTGSEPTLSPALVRRFS
SDART-GEALRGSDSQLCPKPPPKPCKVPFLKT---------------PPSPSPWLTSEANYCELNPAFAVGC----DRG
AKLPMQAHDSHEMLLTAKQNGPSGPR------NSGINYMILDG-DDQAR----------------HWDPLAVQTDEG---
-QEDKTKFVPPLMETVSSFRPNDFESKLLPP-ENKPLETAMLKHAKELFTNHDARVIAQHMLSVDCKVARILEVSEDRKR
-SM---------GVSSGLELITLPHGRQLRLDIIERHNTMAIGIAVDILGCTGTLENRAGTLNKIIQVAVELKD-AMGDL
YAFSAIMKALEMPQITRLEKTWTALRHHYTQTAILYEKQLKPFSKILHEGRE-STYVPASNVSVPLLMPLVTLMERQ---
----------------AVTFEGTDMWENNDESCEILLNHLATAR-FMAEASESYRMNAERILAD-F-QPDEEMTEILRTE
FQMRLLWGSKGAEVNQNERYDKFNQILTALSRKLEPPSGKQAEL------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------
>Rattus_norvegicus_BCAR3
------------------------------------------------------------------------MAAGKFAS
LPRHM--PV--NHQFPLASSMDLLSSKSPL-AEHRTE-----------AYPDVSIHGTLPRKKKGPPPIRSCDSASHMGT
LPHSKSPRQSSPLTQDLILEKPL---------------------------------------------------------
----------------------------------------------------------------------PDWKGDSFAF
RDPYLLDPTL---EYVKFSKERHIMD------RTPER-LKKELEEELL-LSSED----------LRSHAWYHGRIPR---
QVSENLVQRDGDFLVRDSLS----SPGNFVLTCQWKNL-AQHFKINR-TVLRL---SEAYSRVQYQFEMESFDSIPGLVR
CYVGNRRPISQQSGAIIFQPINRTVPLWCLEERYGTS-PG-------RGREGSFAEGRPDVVKRL-------SLTTGG--
-----------IQARDHSLPRGN-------------------------LLRNKDK--------SGSQPACLDHVQDRKA-
------------------------ATLKAHQSESHLPIGCKLPPQSP---SVDTSPCPNSPVFRTGSEPTLSPALVRRFS
SDARA-GEALRGSDSQLCPKPPPKPCKVPFLKV---------------PPSPSPWLNSEANYCELNPAFAVGC----DRG
AKLLSQALDSHEMLLTAKQNGASGPR------NSGINYSILDG-DDQGR----------------HWDPLAVQTDEG---
-QEDETKFVPPVMETVSSFRPNDFESKLLPP-ENKPLETAMLKHAKELFTNHDARVIAQHMLSVDCKVARILEVSEDMKR
-SM---------GVSSGLELITLPHGRQLRLDIIERHNTMAIGIAVDILGCTGTLENRAGTLNKIIQVAMELKD-TMGDL
YSFSAIMKALEMPQITRLEKTWTALRHHYTQTAILYEKQLKPFSKILHEGRE-STYVPASSVSVPLLMPLVTLMERQ---
----------------AVTFEGTDMWEKNDESCEIMLSHLATAR-FMAEASESYRMNAERVLAD-F-QPDEEMTEILKTE
FQMRLLWGSKGAEVNQNERYDKFNQILTALSRKLEPPSGKQAEL------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------
>Oryctolagus_cuniculus_BCAR3
---------------MLALCRKQFEEKAIDCFNNFCDFLRQTELLPPRHTWILKAAKFRFLGPVPNIKELRVMAAGKFAS
LPRNM--PV--SHPSPLASSMDLLSSTSPL-AEHHAD-----------AYPDASIHGTLPRKKKGPPPIRSCDSFSHMGT
LPHAKSPRQSSPRTQDVIRESPL---------------------------------------------------------
----------------------------------------------------------------------QDWKGETFTF
RDLHLLDSTL---DYVKFSKDRHVMD------RTPER-LKKELEEELL-LSSED----------LRSHAWYHGRIPR---
QVSENLMQRDGDFLVRDSLS----SPGNFVLTCQWKNL-AQHFKITR-TVLRL---SEAYSRVQYQFETESFDSIPGLVR
CYVGNRRPISQQSGAIIFQPINRTVPLRCLEERYGTT-PG-------RARDSSLAHGRPDVTRRL-------SLSPGS--
-----------VQAREQSLPRGN-------------------------LLRNKEK--------SGSQPACLDHMQDRRA-
------------------------LSLKAHQSESYLPIGCKLPPQPP---GVDTSPSPNSPVFRTGSEPTLSPAVVRRVS
ADPRS-GEALRGSDSQLCPKPPPKPCKAPVLKA---------------PLSPPTQLSAEANYCELNPACAAGG----DHG
VRPPLCALGSHVQLPTARLSEAPGSR------NSGTSYLILDG-DDGAR----------------PWEPPAAQMEEGT--
CKEDTGEFVAPLLETVSSFRPNDFESKLLPP-ENKPLETAMLKRAKELFASHHPRVIAQHLLHTDCKVARILEVSEETRR
-NM---------GVSSGLELLTLPHGRQLRLDIIERHNTMAIGVAVDILGCTGSLEDRAATLNRIIQVAAELKD-AVGDL
YSFSAIMKALEMPQITRLEKTWTALRHQYTQTAILYEKQLKPFSKVLHEGRE-PTCVPPCSVSVPLLMPLVTLMERQ---
----------------AVTFEGTDLWEKHDQSCEIMLNHLAAAR-LMAQAADSYRANAERMLAG-F-QPDEEMSEVFKTE
FQMRLLWGSKGAEVNQTERYEKFSQILTALSRKLEPPPAKQAEL------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------
>Canis_familiaris_BCAR3
------------------------------------------------------------------------MAAGKFVN
LPRNM--PV--NHQFPLASSMDLLSSKSPP-AEHHTD-----------AYQDVSIHGTLPRKKKGPPPIRSCDNFSHMGT
LPHSKSPRQSSPLTSAIIQEHPL---------------------------------------------------------
----------------------------------------------------------------------QDWKGETFTF
RDQHLLDPTL---EYVKFSKDRHVMD------RTPER-LKKELEEELL-LSGED----------LRSHAWYHGRIPR---
QVSENLVQRDGDFLVRDSLS----SPGNFVLTCQWKNL-AQHFKIHR-TVLRL---SEAYSRVQYQFETESFDSIPGLVR
CYVGNRRPISQQSGAIIFQPINRTVPLRCLEERYGAS-PG-------R---------RPDVGKRL-------SLTMGG--
-----------VQAREQSSPKGN-------------------------LLRNKEK--------SGSQPACLDHMQDRRA-
------------------------LSLKAHQSESYLPLGCKLSSRSP---SVDTSPRPNSPVFRTGSEPTLSPALVRRVS
SDARA-GEALRGSDSQLCPKPPPKPCKAPLLQP---------------PPSPSTWLNSEANYCELNPAFATGG----DRG
ARPPLCAHDSYVELLTAKQNGVLGPR------HSGTNYLILDD-D-GAG----------------PGEAPATQMDQG---
QQEDEGEFVLPRLETASSFRPNDFESKLLPA-ENKPLEMAMLKRVKELFTSKDPKAIAQHMLSTDCMVARILAVSEETRR
-NM---------GVSSGLELLTLPYGHQLRLDIIERHNTMAIGIAVDILGCTSTLEDRAATLNRIIQVAVELKD-SMGDL
YSFSAIMKALEMPQITRLEKTWTALRHQYTQTAILYEKQLKPFSKMLHEGRE-SMCVPPNKISVPLLLPLVTLMERQ---
----------------AVTFEGTDMWEKNDESCEIMLNHLATGR-LMAETADSYRMNAERILEG-F-QPDEEMSEIFKTE
FQMRLLWGSKGAQVNQTERYEKFNQILTALSRKLEPPPVKQAEL------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------
>Felis_catus_BCAR3
--------------------------------------------------------------------------------
---------------------------------------------------------------------MHCSQFSYL--
-PFS----------------------------------------------------------------------------
------------------------------------------------------------------------------LF
RDQHLLDPTL---EYVKFSKERHVMD------RTPER-LKKELEEELL-LSGED----------LRSHAWYHGRIPR---
QVSENLVQRDGDFLVRDSLS----SPGNFVLTCQWKNL-AQHFKIHR-TVLRL---SEAYSRVQYQFETESFDSIPGLVR
CYVGNRRPISQQSGAIIFQPINRTVPLRCLEERYGAS-PG-------RAREGSLAEGRSDVGKRL-------SLTMGG--
-----------LQAREQSSTRGN-------------------------LLRNKEK--------SGSQPACLDHMQDRRA-
------------------------LSLKAHQSESYLPIGCKLPPQSP---GVDTSPCPNSPVFRTGSEPTLSPAVVRRVS
SDARA-GEALRGSDSQLCPKPPPKPCKAPVLKA---------------PPSPSTWLNSEANYCELNPGFAAGC----DRG
TRPPLCAQDSYVELLTAKQNGAPGPR------NSGINYLTLDD-DVGAG----------------PWEAPATQKDQG---
Q-EDEVEFVPPRLETASSFRPNDFESKLLPP-ENKPLETAMLKRAKELFTNNDPKVIAQHMLSMDCVVARILEVSEEMRK
-NM---------GVSSGLELITLPYGHQLRLDIIERHNTMAIGIAVDILGCTGSLEDRAATLNRIIQVAVELKD-SMGDL
YSFSAIMKALEMPQITRLEKTWTALRHQYTQTAILYEKQLKPFSKILHEGRE-STCVPPNKISVPLLMPLVTLMERQ---
----------------EVTFEGTDMWEKNDESCEIMLNHLATAR-LMAEAADSYRMNAERILEG-F-QPDEEMSEIFKTE
FQMRLLWGSKGAQVNQTERYEKFNQILTALSRKLEPPPVKQAEL------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------
>Bos_taurus_BCAR3
------------------------------------------------------------------------MAAGKFAS
LPRNM--PV--NHQFPLASSMDLLSSKSPL-VERRAD-----------AYQDVSIHGTLPRKKKGPPPIRSCDNFSHVGT
LPHSRSPRHHSPLIQDVIQEQPL---------------------------------------------------------
----------------------------------------------------------------------QDWKGEAFTF
RDQHLLDPTL---EYVKFSKERHVMD------RTPER-LKKELEEELL-LSSED----------LRSHAWYHGRIPR---
QVSENLMQRDGDFLVRDSLS----SPGDFVLTCQWKNL-PQHFKIRR-TVVRL---SEAYSRVQYQFEMESFDSIPGLVR
CYVGNRRPISQQSGAIIFQPVNRTVPLRCLEERYGASSPD-------RAHEGSLTEGRPDAAKRL-------SLTVGG--
-----------TQAREQGLPRGN-------------------------LLRNKEK--------SGSQPACLDHMQDRRA-
------------------------LSLKAHQSESYLPIGGKLTPQSP---SVGTSPCPNSPVFRTGSEPTLSPAVVRRVS
SDARP-GEALRGSDSQLCPKPPPKPCKAPLLKA---------------PPSPSIWLNSEANYCELNPALAASY----DGA
SRLPFCAQDSYVELLTAKQNGGLGTR------NSDTSYLILDD-DDRTR----------------PWKPPPAPGDTV---
-GEDQDTFVMPLLETTSSFKPNDFESKLLPP-ENKPLETSMLKRAKELFTNSDPKVIAQHLLSVDCKVARILEVSEEMRK
-NM---------GVNSGLELITLPYGHQLRLDIIERHNTMAIGIAVDILGCTGSLEDRAATLNKIIQVAVELKD-SMGDL
YSFSAIMKALEMPQITRLEKTWTALRHQYTQTAILYEKQLKPFSKVLHEGRE-STCVPPNNVSVPLLMPLVTLMERE---
----------------AVTFEGTDMWEKNDESCEIMLNHLATAR-LMAEAADSYRMNAEKILAG-F-QPDEEMSEVFKTE
FQMRLLWGSKGAQVNQTERYEKFNQILTALSRKLEPPPVKQMEF------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------
>Gallus_gallus_BCAR3
-----------------------------------------------------------------------MIAAGKFSS
LPRNV--PVNVNHQFSLASSMDLLTTKPSL-TEHRSD-----------SFQDISIHGTLPRKKKGTVKVRACDMFSHVGM
LPYTRTQRQQPPFVQDVIEEYPL---------------------------------------------------------
----------------------------------------------------------------------QNGKSNKLHT
RDQNIPDPTL---EYVKFSKERQVMD------NSPEK-LKKELEEELQ-LSSED----------LRSHAWYHGRIPR---
QVAEDLVQRDGDFLIRDSLS----CPGNFVLTCQWKNT-SQHFKINR-TILRL---SEAYCRVQYQFELESFDSIPGLVR
YYVGNRTPISKQSGAIIFQPINRTVPLRCLEEKYGVI-PD-------RQKEQSIPEGKTEAAKRL-------SLGISS--
-----------MQSQEQSIPRGN-------------------------LLRNKEK--------SGSQPASLDHVLDKR--
------------------------FPLKTHQSESYLLIGSRHSSRLP---EADADSCPSSPAFRTGSEPSLSPTVVQKVT
YDSQV-GEALRGSDSQLYPKPPPKPSKATLLKT---------------TDSPMASHSSEGHYCELSLVRD-------SAA
TEH-LCQKNSYVEHLTQKERGRQCFR------NSETSYLILDD-DHTVN----------------SAGPLDVSTETA---
--EENNVFSAPLFETSSSFKPNDFESKLLPS-ENKPLETSMLRKIKELFTKNNPKVIAQHILRMDCKVARILEVSEEMRR
-IM---------GVNSGLELITLPYGHQLRLDLIERHNTMAIGIAVDILGCTGNLEDRAATLNKIIQVAVELKD-SLGDL
YAFSAIMKALEMPQVSRLEQTWTSLRHHYTQTAIMYEKQLKPFSKALHEGQE-MVSVPQN-LTLPLLMPLVTLMERQ---
----------------AVIFEGMDLWESSDQSCEIMFKHLTTAR-QIAQNAEMYSLTAQRMLEG-F-QPDEEMSEIFKTE
FQMRLLWGSKGAQVNQNERYEKFSQILTALSRKLEPPPVKQVEQLSI---------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------
>Taeniopygia_guttata_BCAR3
-----------------------------------------------------------------------MIAAGKFSS
LPRNS--PV--NHQFSLASSMDLLTTKPSP-IEHHSN-----------SFQGISIHGTLPRKKKGTIPSRSCDMFSHVGA
LPYTR-AWQQPPFVQDVIEEYPP---------------------------------------------------------
----------------------------------------------------------------------DNGKSSELHA
RDKNILDPTL---EYVKFSRERQVMD------KSPEK-LKKELEEELQ-LSSED----------LRSHAWYHGRIPR---
QVAEGLVQRDGDFLIRDSLS----SPGNFVLTCQWKNT-PQHFKIIK-TVLRL---NEAYCRVQYQFELESFDTVPGLVR
YYVGNRTPISKQSGAIIFQPVNRTVPLRCLEEKYSVT-PV-------QQKEPRTPEGKMESAKRL-------SLGISS--
-----------MQYPDQSMPRGN-------------------------LLRNKEK--------SGSQPASLDHVLEKR--
------------------------FPLKAHQSESYLLIGSRHPSRLP---EADANSCPSSPAFRTGSEPSLSPTVVQKVT
SESQL-GEALRGSDGQLCPKPPPKPSKAPLMKL---------------PDSPLASHSSEGHYCELNPARHP------TAA
KQC-LCQKNSYVEHLTQKER--ATFR------NSETSYLIIDD-DPTMH----------------PADPLEA--QMA---
--EEDSIFSAPVYETVSSFKPNDFESKLLPP-ENKPLETSMLRRVKELFTNNNPKIIAQHILRMDCKVARIVEVSEEMRR
-NM---------GGNSGLELITLPYGHQLRLDLIERHNTMAIGIAVDILGCTGNVEDRAATLNRIIQVALELKE-SLGDL
YGFSAIMKALEMPQVSRLEQTWTALRHCYTQTAIMYEKQLKPSCKALHEGQDDMCFAPQNNVTVPLLMPLVTLMERQ---
----------------AVVFEGMELWESSDQSGEIMLRHLGTAR-LIAQHAETFRLTAEQLLQG-F-QPDEELSEIFKTE
FQMRLLWGSKGAQVNQSERYEKFNRILTALSRKLEPPPVKLVEQ------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------
>Anolis_carolinensis_BCAR3
MKHISISSWLSQLGLPEYGTLFDQQYDGVEDLLHLTEAELKRMGVKNQIHRTHIISNISLLQEAERKQELRMIAAGKFAS
LPRNM--QM--SHEFSLASSMDLLTSKPSLAADHRSG-----------ICQDVSIHGTLPRKKRGPIPVGSSDPLHHMGT
SPYCKGLRTQGPSIQNIIEEYPQ---------------------------------------------------------
----------------------------------------------------------------------KNKKNDNFFS
RDQNVADPTI---EYVKFSKERQVMERQVTMDSSPEK-LKKELEEELQ-MSSED----------LRSHAWYHGRIPR---
QVAESLIQRDGDFLIRDSLS----SPGNFVLTCQWKNI-SQHFKINK-TILRL---NEAYCRVQYCFEDESFDSIPGLVR
CYVGNRRPISKQSGAIIFQPINRTVPLRCLEEKYGIS-PG-------MQREGSIPEGQVDTPKRL-------SLNMCN--
-----------RLAREQNSVRGN-------------------------LLRNKEK--------SGSHPACLDHVQEKR--
------------------------FPLKAHQSESFLPIGSRHLSQGT---EAETSPCRKSPAFRTGSEPALSPLMFRRFA
SELQI-NDVLRGSDSQLYPKPPPKPSKVPFLR---------------------PSHGSEVLYCELNAALPADC----RIS
KQS-LCQKNNFVDYLTTKENG----T------HPEPNYLILDNRDSFLS----------------SVDPLTAQTEMS---
--NESDVFVAPVLEMVSSFQPNHFESKLLPS-ENKPLETAMLKKVKEFFTNNSAKTIAHHILKMDCKVARILEVSEEMRR
-TM---------GVKSGLELITLPYGHQLRLDIIERHNTMAIGIAVDILGCTGNLEERVTTLNRIIQVAVELKE-SMGDL
YAFSAVMKALEMPQVTRLEQTWTMLRHCYTQTAIMYEKQLKPFCKALHEGRE-IASVPQNIVTVPLLMPLINLLERQ---
----------------TVVFDGMDVWENTDQSCEIMLKHLATAR-LIAQNASLYSRNAERILAG-F-QPDNEMKEIFKTE
FQMRLLWGSKGAQVNQSERYEKFNQILTALSRKLESPQIKQNEL------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------
>Pelodiscus_sinensis_BCAR3
-----------------------------------------------------------------------MIAAGKLAS
LPRNM--QV--NHQFSLASSMDLLSSKPPL-AEHHLD-----------SYQDISIHGTLPRKKKGAIPIRSCDMFSHMGT
LPFPKTHRQQSPLIQDVLEKCSL---------------------------------------------------------
----------------------------------------------------------------------QDRKSEKHQF
RDQNILDPAM---EYVKFSKERQVMD------STPEK-LKKELEEELQ-LSSED----------LRSHAWYHGRIPR---
QVAESLVQRDGDFLIRDSLS----SPGNFVLTCQWKNI-SQHFKINR-TILRL---NEAYCRVQYQFELESFDSIPGLVR
CYVGNRRPVSKQSGAIIFQPINRTVPLRCLEEKYGVS-PV-------RQRECNITEGKTEIARRL-------SLSICS--
-----------VQPQEHSLTRGN-------------------------LLRNKEK--------SGSQPASLDHVQEKR--
------------------------FHLKTHQSESYLPAGLRHPFQLP---EVDTNPRSNSPTFRTGSEPTLSPTVGQRVA
SELPV-GEALRGSDSQLCPKPPPKPNKVPFLRQ---------------PQSPLAWHSSEAHYCELNPATSIDC----EAT
QQP-LSQKSSYVEHLIAKENGLLSFR------NSEESYLIHED-DALLS----------------SMDPLALRTEMA---
--EEASVFVAPVLETESSFKPNDFESKLLPP-ENKPLETPMLKKVKELFTNSNPKIIAQHMLRMDCKVARILEVSEELRR
-SM---------GVSSGLEFITLPYGHQLRLDIIERHNTMAIGIAVDILGCTGNLEERAATLNRIIQVAVELKD-SLGDL
YAFSAVMKALEMPQIARLEQTWTTLRHHYTQTAIMYEKQLKPFSKALQEGGE-TICVPQNNITVPLLMPWVTLMERQ---
----------------FVIFDGLDLWEYTDQSCEIMLKHLATAR-FIAQNADMYRMTAERKLEG-F-QPDDEMSEIFKTE
FQMRLLWGSKGAQVNQRDKSLIFKLIMSLQFKFSPNLLCSPLVK------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------
>Xenopus_tropicalis_BCAR3
------------------------------------------------------------------------MAAGKFAS
YHRNV--QM--NHQFPLVSSMDLLGSKSAL-GERRSD-----------SFQNVCIHGTLPRKKKERVPIKSSDVFCHLGT
LPHSKSHRLPNPVMQDIKEEYPF---------------------------------------------------------
----------------------------------------------------------------------QERRTGIFNM
REYY-LDPSM---EYVKFSKDRYIMDG-----GTPDK-LKKELEEELK-LNSED----------LRSHAWYHGRIPR---
QVSENLVKRDGDFLIRDSLS----SPGNFVLTCQWKNL-SQHFKINK-VVIRL---NEAYCRIQYQLEHESFDSMPALVR
YYVGNRKAVSQQSGAIIFQPINRTVPLRCIEEKYGTS-PV-------RRLELGPLEAKAEVPKRL-------SLNFGQ--
-----------GVSQEQSLARGN-------------------------LLRNKDK--------SGSQPACLDNMREKR--
------------------------RPLKAHQSESYLPLGSRHPCLSQ---GMDVKVSPKAHVFRTGSEPALSPTEIRRFS
NEAHP-AEALRGSDSQLCPRPPPKPSKAPSIKQ---------------SHSPLVWQSSEANYCELHPTPPEDC----AWS
DSY--SSRNSYIEDQRTDDIESLSFS------NSELSFPALDD----------------------SISQCSATNFCG---
-NVEDNEFNRPVYETVSSFCPNDFQSVLLTA-ENKPLETALLRRAKELFTNNDPKTIAKHILRMDCKVARILDVTPEVEK
-MM---------GVSSGLELIILPFGHQLRLDLMERHTTMAIGIAVDILGCTGNLEERVATLHKIIQLAVEVK--ALGDY
FAFSAIMKALDMPQITRLEQTWTMLRHQYTHTAITYEKQLKPFSKYLHEGEA---LDTQEDLTVPLVMPLVALLERQ---
----------------SVIFEGMDFWENHDRGCEIMFNHLQTAR-QVAQYASVYRKNAERILEG-F-KPDELMSEIFKTE
FQMRLLWGSKGALLKQSERYHKFGQILTALSRKLEPPS------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------
>Danio_rerio_BCAR3_a
MKHMSISKWLSQLGLPQYCILFDEEYDGVEDLLHLTEMDLLGLGVQSRLHRIHILSSIQVLRERETKRELRMMAEGRFSS
LPRNMHV----GRQCPLASSMDLLSSRPEL-SEMPVS-----------GYQGISIHGTLPRKKKTTTGSPVKQWEVNGNV
GSLAAPYPGRHRLPPSPLIHNII---------------------------------------------------------
----------------------------------------------------------------------EEHQTFCSDR
KQSRNSAGMDPTMEYVKFSRDKYILD------GPPEK-LRRELEEELK-LSSEE----------PRSHAWYHGAIPR---
QVAENLVQRDGDFLIRDSLS----SPGNYVLTCQWKNS-PQHFKINK-RVVAM---NEAYSRVQYLFEKEGFDSIPALVR
YYVGNREPVSEVIGAIIFQPINRALPLRCLEEKYGVG--S-------IRVEAGYLERKSLTSKRL-------SLNIMN--
-----------GHGQDHTLSRGN-------------------------LLSNKDK--------CGSQPACLNHVQERR--
------------------------RPLKTHQSESFLPIGS--RPQAQV-QHMEHQPCPKSPVFRTGSEPALSPTVPRRMA
FDTLP-GEAIRGSDSQLCPKPPPKPSKVPTVRVPCIPALKTLVVPPVPPVKPHKHRPSLQQQQSGSPEMSYCE----LSP
CSPADWEKMNSLQANGYVERLKTDGS------IKLDRSSYHNAIEALDN---------------DSEEDTEEDADKEQ--
--NGKKAFQKPVFETESAFRPANVNFRLLPK-ENKPLEMTVLKKAKELLVSQDPKTIAKHILQADCQVARILNVSEEVKG
-QM---------GVSSGLELVTLPHGRQLRLDLIERHNTMAIGVAVDILGCTGSLEERAATLNRIILVALELKD-SMGDL
YAFSSIMKALDMPQITRLDHTWTSLRRKYTQTAIIYEKSLKPFYKGLYEGGAEIPLS---NASVPLLMPLLTLMERP---
----------------AVTFEGMDVWENTDQGCEIMFRHLEGAR-AVARNADTYTCNAQRILQD-F-QPHEDMLEILRTD
FQLRLLWGSRGAAVEQTERYDKFKLILTALSRKLEPAVKHTEL-------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------
>Takifugu_rubripes_BCAR3_a
------------------------------------------------------------------------MSER----
--------------CTLKTLTATLC-------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------CFYQ
KSSVITA---------KFSRDQFILE------CPSEK-LRKELEEELK-MDCEE----------LRSHAWYHGAIPR---
QVAETLVQRDGDFLIRDSLS----SPGSYVLTSQWRNT-AQHFKINK-KVVTL---NEAYTRVEFRLDREGFDNVPALIR
YYVGNRKPVSPVVGAIIFQPINRVLPLRCLEEKYGVS--N-------NHRER-LMVQERRSQKRL-------SLNITN--
-----------GHAHDGNLSSP----------------------------RTKDR--------CGSQPASLNQVHDRR--
------------------------RPLKAHQSESYLPLGKRAPPHPLA-DSVPLSPSHKSPVFRTGSEPVLSPSVPRRSA
ELLS--GQPIRGSDSQLCPKPPPKPSKVLLSRL------------CPPADPPSLNAPQLDSSCAETPALPRRT----GVD
LQVPLCGHVERLRREEVGEGEAVGRR------G-LDRSSYHHASAPLEY---------------TSEEEEEDRKRK----
----TLGFLRPIVETESTFRPADFGSRLLPP-ENKPLEMLVLKRAKELLLSHDHQSIARHLLKADCQVARIIGVTPELKS
-QM---------GVASGLELVTLPHGRQLRLDLMERHHTMAIGVAVDILGCTGSVDERATTLNRIILVALELKD-AVGDL
FAFTALMKALDLPQISRLEETWTTLRRNYTQTAISYEKTLKPFFKNLYEGTASCPP----TVCVPVLLPLLTLMERS---
----------------SVMSEGAELWETNDQGCDIMLRHLEAAR-GVAHNTWSYAQNAEKMLQE-F-RCDDELLEVFKTD
FQLRLLWGSRGACVNQSDRYNKFNLILTALSRKLEPPPKTQTVI------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------
>Gasterosteus_aculeatus_BCAR3_a
------------------------------------------------------------------------MSEG----
--------------CSLKTLTAALC-------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------CFYH
KNSVMTA---------KFSRDQFIVD------CPSEK-LRKELEEELK-MNCEE----------PRSHAWYHGAIPR---
QVAEYLVQRDGDFLIRDSLS----SPGCYVLTCQWRNA-AQHFKINK-KVVML---NEAYSRVEYRLEREGFDNVPALIR
YYVGNRKSVSQVVGAIIFQPINRGLPLRCLEEKYGLS--S-------HRRDA-LMAQERRSRKRL-------SLNVTN--
-----------GHAQDDARGAQNGARGRG--------------------LRFKDR--------CGSQPASLNQVPERR--
------------------------RPLQAHQSESYLPLGS--KPQRSP-DPLLPSPSPKSPVFRTGSEPVLSPSVPRRPA
ELLA--GQAIRGSDSQLCPKPPPKPSKVPLAR--------------PPAPPPGAPGLTHATSGSNAPALASAC----VQT
LASPRS--SEGINSEIVYSASAGPPV------PPVKPLKFLHQLRPEDTR---G--------FSTSALSPTENGWK----
----RSRFQRPVEETESAFQPAQFGSRLLPP-ENKPLETVVLKRAKELLLSHDHHSIARHLLLADCQVARTVGVTPEVKG
-QM---------GVSSGLELVTLPHGRQLRLDLMERHHTMAIGVAVDILGCTGSVDERASTLNRIILVALELKD-AVGDL
FAFTALMKALDLPQISRLEETWTTLRRTYTQTAISYEKTLKPFYKNLYEGTASSPA----VVCVPLLLPLLTLMERP---
----------------SITPEGAELWETSDQGCDIMLRHLEDAR-DVAHNAQRYTINSQMILEG-F-PCDEDLLEVFKTD
FQLRLLWGSRGASVNQSDRYNKFNLILTALSRKLEPPPNTQIVI------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------
>Oryzias_latipes_BCAR3_a
------------------------------------------------------------------------MSER----
--------------CNLKALTAALC-------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------CFNH
KNSVISG---------KFSRDQFILD------CSSEK-LRRELEQELK-MNCEE----------PRSHAWYHGAIPR---
QVAENLVQRDGDFLVRDSLS----SPGSYVLTCQWRNA-PQHFKVNK-KVVML---NEAYSKVEYRLDKDGFDSVPSLIR
FYVGNRKPVSQVVGAIIFQPINRSLPLRYMEEKYALS--G-------NQREAGLVAQEKPCQKRL-------SLNITNGI
-----------GHPVQDGSHCPDNSLSRSS------------------HLRLKDR--------CGSQPASLNQVQERR--
------------------------RPLKAHQSDSFLPLGSKPQSQQSP-DPLLPSP--KSPVFRTGSEPALSPCVPRRSA
EHQAAAGQAIRGSDSQLCPKPPPKPSKLLLAQS------------PQAPSVQPSRSPASSPSWAVSPLAASSC----SAA
TACPKTSQRTYMQLSDCRPSRSPGKA------P----NSYHHTIEASEH---------------TSEEEEEEDGERDLPK
RGKVRGGFRRPVEETESMFRPTDFESRLLPP-ENKPLEMVVLRKAKELVLSHDHQSLARHLLMADCQVARILGVTPEMKG
-QM---------GVSSGLELVTLPHGRQLRLDLMERHHTMAIGVAVDILGCTGSVEERASTLNRIILVAQELKD-EVGDL
YAFTALMKALDFQQISRLEETWTTLRRNFTQAAISYEKILKPFYKSLYEGTVSSAAPSSKALCLPMLLPLLTLMERP---
----------------LIPPEGAEFWETSDEGCDIMLRHLEAAR-IVAQNAQSHTSNAQMILKG-F-EFDEGLLEVFKTD
FQLRLLWGSRGATVNQSDRYNKFNLILTALSRKLEPPATTQPLI------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------
>Nematostella_vectensis_BCAR3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------------------MSK
KSNKLSRTFPGRVKNETKSRQPLPSG-----FKRFADFLTLRRKKRKGDSAARQ----------LEKSPWFHGKITA---
EYAEMLMRGAGEFLVREDPA----MPGMYFIAVRNKEQETLHLAITK--VNHS---KGTRIKYRVEDSDYMFDGIPELIQ
FYISERRPVSIRPPAVLTIAISKESALLKEEDFRGRTSTAG------SARIHRTTRGRLERKRSD---------------
------------PVLSTRVPSRVFN-----------------------IEADDDS----------SASVPDKDRPHSRSN
------------------------PPSIYYDDKQKTAEGGELFSSATTQSLEDVLDPPQIERRRHLSSSGSAPSLYRKRD
SGEGP--ESTYDSPRSIAIPTTTLKHVSPYGRQG------------------RKRSQESGPVQALKSKEGVPLK------
---------DYATPSSLPVNGSSNSQDELDYDVPRPSSMVTDK----------------------NNDDTNSKRDSG---
----VTRESSTERDRAGSGVTECAKPRQTRQEIYQSVLQKLRDKIVRPFLEQSCVTLARYMTKVDLDVVWTSHMGEGEGE
-PE---------GVAEGLELLILPQGRDIRSALIERYTNLTYWVG-ALVVAAGDLGPRTQVVTKLIELADVLSD-KHGNL
VSFMAVLEGLALPQVTRLHHTWSCLHHQYSSSAIMYHSTLKPLAGLLSSGAP----SPFPGVCLPYVVPLAKLLEMT---
----------------TEDALGGWGQDDVVQGIETLLAHLDAGR-TLIQQLDAYKDEYLKRSHETIPEDELKIMDYFRSR
VNVGDVLGLGSDAHVRTQKLVTLLNWLSENAERASKPSADIWQATNAMAISIVCKPFDFFAIMKSGRLKGQIGRMNRGAN
LSAKIRLFSLHLKFPTDEKFTISRVCPGMTVKDLKNRIELETGVPRHLLRLRYLDGYDLTDDRRLSYYNMVPAATVQVLL
WPEWVSLVTAACKGDYYGNQIGVFNFFRGVLASQIRTPAKLGQNTPREFNEKALVALYIASHRGHVNVVSRLVESGVYPC
TKLPSGRSPLHAAVNRKQITCVSILIGELYIDRVILSSAGRD
>Hydra_magnipapillata_BCAR3
--------------------------------------------------------------------------------
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--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------MSVILG-------------SLMYNLDSEIQN-
------------------------TVGRMP--------------------------------------------------
--------IESLNLSPWFHGKIDRATISRLLKH-------------------------DGDFIVREKSDNSG--------
------------TNVLSVLWKGS------------------------------------------IKHFILKANDKG---
------LYTLEGESFSSINALITHHYERRSV-IQSSTGIILMNSVNR---------------------------IFMDG-
------------DDYIVPQ-----------DDVQLKCKLGGGHFGD--------------VYKVLELCDKGDLLALLKKE
GPNFTQMKLFDMSMDIARGMAYLEQKQIIHRDLAARNCLVTNDYDVKISDFGMSREEDDEGTYTIQTTKEIPFKWCAP--
----------------EVWLDTKYSTKTDVWSYGVTLYEIYSLG-QQPYPGWTNKQAREEINAG-YRMPSPAKTPPEVY-
ELMRKCWHFSDFERPSFSEIINIFENIRLHIFKMNFLK------------------------------------------
--------------------------------------------------------------------------------
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------------------------------------------
>Homo_sapiens_SH2D3C
----------------------------------------------------------------------MTEGTKKTS-
KKFKFFKFKGFGSLSNLPRSFTLRRSSASISRQSHLE----------PDTFEATQDDMVTVPKSPPAYARSSDMYSHMGT
MPRPSIKKAQNSQAARQAQEAG----------------------------------------------------------
-----------PKPNLVPGGVPDPPGLEAAKEVMVKATGPLEDTPAMEPNPS--AVEVDPIRKPEVPTGDVEEERPPRDV
HSERAAGEPEAGSDYVKFSKEKYILD------SSPEK-LHKELEEELK-LSSTD----------LRSHAWYHGRIPR---
EVSETLVQRNGDFLIRDSLT----SLGDYVLTCRWRNQ-ALHFKINK-VVVKA---GESYTHIQYLFEQESFDHVPALVR
YHVGSRKAVSEQSGAIIYCPVNRTFPLRYLEASYGLGQGS-------SKPASPVSPSGPKGSHMK-----RRSVTMTD--
------------GLTADKVTRS--------------DGCPTS----TSLPRPRDSIR--------SCALSMDQIPDLHS-
------------------------PMSPISESPSSPAYST-VTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTH
-GESD--KGPHTSPSHTLGKASPSPSLSSYSDP------------------------DSGHYCQLQPPVRGSR-------
------------EWAATETSSQQA--------RSYGERLKE------------------------LSENGAPEGDWG---
-----KTFTVPIVEVTSSFNPATFQSLLIPR-DNRPLEVGLLRKVKELLAEVDARTLARHVTKVDCLVARILGVTKEMQT
-LM---------GVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRG-TMGNM
FSFAAVMGALDMAQISRLEQTWVTLRQRHTEGAILYEKKLKPFLKSLNEGKE---GPPLSNTTFPHVLPLITLLECD---
----------------SAPPEGPEPWGSTEHGVEVVLAHLEAAR-TVAHHGGLYHTNAEVKLQG-F-QARPELLEVFSTE
FQMRLLWGSQGASSSQARRYEKFDKVLTALSHKLEPAVRSSEL-------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------
>Pan_troglodytes_SH2D3C
----------------------------------------------------------------------MTEGTKKTS-
KKFKFFKFKGFGSLSNLPRSFTLRRSSASISRQSHLE----------PDTFEATQDDMVTVPKSPPAYARSSDMYSHMGT
MPRPSIKKAQNSQAARQAQEAG----------------------------------------------------------
-----------PKPNLVPGGVPDPPGLEAAKEVMVKATGPLEDTPAMEPNPS--AVEVDPIRKPEVPTGDVEEERPPRDV
HSERAAGEPEAGGDYVKFSKEKYILD------SSPEK-LHKELEEELK-LSSTD----------LRSHAWYHGRIPR---
EVSETLVQRNGDFLIRDSLT----SLGDYVLTCRWRNQ-ALHFKINK-VVVKA---GESYTHIQYLFEQESFDHVPALVR
YHVGSRKAVSEQSGAIIYCPVNRTFPLRYLEASYGLGQGS-------SKPASPVSPSGPKGSHMK-----RRSVTMTD--
------------GLTADKVTRS--------------DGCPTS----TSLPRPRDSIR--------SCALSMDQIPDLHS-
------------------------PMSPISESPSSPAYST-VTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTH
-GESD--KGPHTSPSHTLGKASPSPSLSSYSDP------------------------DSGHYCQLQPPVRGSR-------
------------EWAATETSSQQA--------RSYGEKLKE------------------------LSENGAPEGDWG---
-----KTFTVPIVEVTSSFNPATFQSLLIPR-DNRPLEVGLLRKVKELLAEVDARTLARHVTKVDCLVARILGVTKEMQT
-LM---------GVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRG-TMGNM
FSFAAVMGALDMAQISRLEQTWVTLRQRHTEGAILYEKKLKPFLKSLNEGKE---GPPLSNTTFPHVLPLITLLECD---
----------------SAPPEGPEPWGSTEHGVEVVLAHLEAAR-TVAHHGGLYHTNAEVKLQG-F-QARPELLEVFSTE
FQMRLLWGSQGASSSQARRYEKFDKVLTALSHKLEPAVRSSEL-------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------
>Macaca_mulatta_SH2D3C
----------------------------------------------------------------------MTEGTKKTS-
KKFKFFKFKGFGSLSNLPRSFTLRRSLAPISRQSHLE----------PDIFEATQDDMVTVPKSPPAYARSSDMYSHMGT
MPRPSIKKAQNSQAVRQAQEVG----------------------------------------------------------
-----------PKPNLVPRGVPDPPGLEAAKEVMVKANGPLEDIPAVEPNPS--AVEVDPIRKPEVPTGDTEEERPPRDV
HSERQAG-EVAGWLFLKFSKEKYILD------SSPEK-LHKELEEELK-LSSTD----------LRSHAWYHGRIPR---
EVSETLVQRNGDFLIRDSLT----SLGDYVLTCRWRNQ-ALHFKINK-VVVKA---GESYTHIQYLFEQESFDHVPALVR
YHVGSRKAVSEQSGAIIYCPVNRTFPLRYLEASYGLGQGS-------SKPASPVSPSGSKGSHMK-----RRSVTMTD--
------------GLTADKVTRS--------------DGCPTS----TSLPRPRDSIR--------SCALSMDQIPDLHS-
------------------------PMSPISESPSSPAYST-VTRVHAAPAAPSATALPASPVTRRSSEPQLCPGSAPKTH
-GESD--KGPHTSPSHTLCKTSPSPSLSSYSDP------------------------DSGHYCQLQPPVRGSR-------
------------EWAAAEASSRQA--------RSYGEKLKE------------------------LSENGAPEEDWG---
-----KTFTVPIVEVTSSFNPATFQSLLIPR-DNRPLEVGLLRKVKELLAEVDARTLARHVTKVDCLVARILGVTKEMQT
-LM---------GVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRG-TMGNM
FSFAAVMGALDMAQISRLEQTWVALRQRHTEGAILYEKKLKPFLKSLNEGKE---GPPLSNTTFPHVLPLITLLECD---
----------------SAPPEGPEPWGSTEHGVEVVLAHLEAAR-TVAHHGGLYNTNAEVKLQG-F-QARPELLEVFSTE
FQMRLLWGSQGASSSQARRYEKFDKVLTALSHKLEPAVRSSEL-------------------------------------
--------------------------------------------------------------------------------
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------------------------------------------
>Callithrix_jacchus_SH2D3C
--------------------------------------------------------------------------------
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-------------------------------------------------------------------------------M
HSERAAGELEAGGDYVKFSKEKYILD------SSPEK-LHKELEEELK-LSSTD----------LRSHAWYHGRIPR---
EVSETLVQRNGDFLIRDSLT----SLGDYVLTCRWRNQ-ALHFKINK-VVVKA---GESYTHIQYLFEQESFDHVPALVR
YHVGSRKAVSEQSGAIIYCPVNRTFPLRYLEASYGLGQGS-------SKAASPASPSGPKGSHMK-----RRSITMTD--
------------GLTADKVTRS--------------DGCPTS----MSLPRPRDSIR--------SCALSMDQIPDLHS-
------------------------PMSPISESPSSPAYST-VTRVHAAPAAPSATALPASPVARRSSEPQLCSGSAPKIH
-GESD--KGPHASPSHTLCKASPSPSLSSYSDP------------------------DSGHYCQLQPPVRGSR-------
------------EWAAAEASSRQA--------RSYGEKLKE------------------------LSENGAPEGDWG---
-----KTFTVPIVEVTSSFNPATFQSLLIPR-DNRPLEVGLLRKVKELLSEVDARTLARHVTKVDCLVARILGVTKEMQT
-LM---------GVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRG-TMGNM
FSFAAVMGALDMAQISRLEQTWVTLRQRHTEGAILYEKKLKPFLKSLNEGKE---GPPLSNTTFPHVLPLITLLECD---
----------------SAPPEGPEPWGSTEHGVEVVLAHLEAAR-TVAHHGGLYHTNAEVKLQV-L-HCRPELLEVS-AR
SQMRLLWGSQGSSSSQARRYEKFDKVLTALSHKLEPAIRSSEL-------------------------------------
--------------------------------------------------------------------------------
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------------------------------------------
>Mus_musculus_SH2D3C
----------------------------------------------------------------------MTEMPKKTG-
RKFKFFKFKGLGSLSNLPRSFSLRRSSASASIRSCPE----------PDTFEATQDDMVTLPKSPPAYARSSDMYSHMGT
MPRPNIKKAQKQQAVQKAQEVS----------------------------------------------------------
-----------RESHLVSRRLPEPPDLEAAKEAGEGTEALLEDT-----APS--AVEVDPMRELEDLTVDTEKEQVPGDV
SPERTAAELEAAGDYVKFSKEKYILD------SSPEK-LHKELEEELK-LSSTD----------LRSHAWYHGRIPR---
EVSETLVQRNGDFLIRDSLT----SLGDYVLTCRWHNQ-ALHFKINK-VVVKA---GESYTHIRYLFEQESFDHVPALVR
YHVGSRKAVSEQSGAIIYCPVNRTFPLRYLEASYGLSQGS-------SKTASPASPSGSKGSHMK-----RRSITMTD--
------------GLTTDKVTRS--------------DGCPNS----TSLPHPRDSIR--------NCALSMDQIPDLHS-
------------------------PLSPISESPSSPAYST-VTRVHAPSATPSTSAQPASPVARRSSEPQLCPGNTPKPP
-GESD--RAPHASPSHTLCKASPSPSLSSYSDP------------------------DSGHYCQLQPPVRGSR-------
------------EQAAGETP-RKA--------RGSGERQKE------------------------LLENGVSDGEWG---
-----KTFTVPVVEATSSFNLATFQSQLIPK-ENRPLEVALLRKVKELLSEVDARTLARHVTKVDCLVARILGVTKEMQT
-LM---------GVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRG-TMGNM
FSFAAVMGALEMAQISRLEQTWMTLRQRHTEGAILYEKKLKPFLKSLNEGKE---GPPLSNTTFPHVLPFITLLECD---
----------------SAPAEGPEPWGSTEHGVEVVLAHLEAAR-TVAHHGGLYHTNAEVKLQG-F-QARPELLEVFSTE
FQMRLLWGSQGANSSQAWRYEKFDKVLTALSHKLEPAIRSSEL-------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------
>Rattus_norvegicus_SH2D3C
----------------------------------------------------------------------MTEMPKKTG-
KKFXXXKFKGLGSLSNLPRSFSLRRSSASPSIRSCPE----------PDTFEATQDDLVTLPKSPPAYARSSDMYSHMGT
MPRPNIKKAQKQKAVQKAQEVS----------------------------------------------------------
-----------RESHLVSRGLPEPPDFEAAKEAEKGTETPLEDT-----TPS--AVEVDPMRKLAGLTVDTAEKQIPGDA
YPERAAAELEAAGDYVKFSKEKYILD------SSPEK-LHKELEEELK-LSSTD----------LRSHAWYHGRIPR---
EVSETLVQRNGDFLIRDSLT----SLGDYVLTCRWHNQ-TLHFKINK-VVVEA---GESYTHIRYLFEQESFDHVPALVR
YHVGSRKAVSEQSGAIIYCPVNRTFPLRYLEASYGLSQGS-------SKAASPASPSGPKGSHMK-----RRSVTMTD--
------------GLTSDKVTRG--------------DGCPNS----TSLPHPRDSIR--------NCALSMDQIPDLHS-
------------------------PLSPISESPSSPAYST-VTRVHAASAAPCT-AQPASPVARRSSEPQLCPGGAPKPP
-GESD--RGPHASPSHTLCKASPSPSLSSYSDP------------------------DSGHYCQLQPPVRCSR-------
------------EPTAGETP-RKA--------RSSAERQKE------------------------LSENGVPEGEWG---
-----KTFTAPVAEATSSFNLATFQSQLIPK-ENRPLEVGLLRKVKELLSEVDARTLARHVTKVDCLVARILGVTKEMQT
-LM---------GVRWGMELLTLPHGRQLRQDLLERFHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRG-TMGNM
FSFAAVMGALEMAQISRLEQTWMTLRQRHTEGAILYEKKLKPFLKSLNEGKE---GPPLSNTTFPHVLPFITLLECD---
----------------SAPAEGPEPWGSTEHGVEVVLAHLEAAR-TVAHHGGLYHTNAEVKLQG-F-QARPELLEVFSTE
FQMRLLWGSQGANSSQAWRYEKFDKVLTALSHKLEPAIRSSEL-------------------------------------
--------------------------------------------------------------------------------
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------------------------------------------
>Canis_familiaris_SH2D3C
----------------------------------------------------------------------MTEGPKKAS-
RKFKFFKFKGLGSLSNLPRSFTLKRSSTSSSIESHLE----------PDTFEATQDDMVTVPKSPPAYARSSDMYSHMGT
MPRLSIKKARDPQATHKTKEVG----------------------------------------------------------
-----------LEPHLVAQGLPNPPGLEAAKEVVVETKPPLEDTPAVGPNP----SAMSPTEKPKDPRADRKEERDPRNV
PPERVAGEPEAGGDYVKFSKEKYILD------SSPEK-LHKELEEELK-LSSTD----------LRSHAWYHGRIPR---
EVSETLVQRNGDFLIRDSLT----SLGDYVLTCRWRNQ-ALHFKINK-VVVKA---GESYTHIQYLFEQESFDHVPALVR
YHVGSRKAVSEQSGAIIYCPVNRTFPLRYLEACYGLGQGS-------SKAASPASPSGPKGGHMK-----RRSVTMTD--
------------GLTADKVTRSS-------------DGCPAS----TSLPHPRESIR--------NCALSMDQIPDLHS-
------------------------PMSPISESPSSPAYST-VTRVHATSAAPSATALPASPVTRRSSEPQLCPGSTPKPP
-GESD--KGPYASPSHTLCKASPSPSLSSYSDP------------------------DSGHYCQLQPPVRGSR-------
------------EWAMAEASGRQA--------RSYGERLKE------------------------LSENGASEGDWG---
-----RAFTAPVVEATSSFNPATFQSLLIPK-DNRPLEVGLLRKVKELLAEVDARTLARHVTKVDCLVARILGVTKEMQT
-LM---------GVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRG-TMGNM
FSFAAVMGALDMAQIARLEQTWVTLRQRYTEGAILYEKKLKPFLKSLNEGKE---GPPLSNTTFPHVLPLITLLECD---
----------------SAPAEGPEPWGSTEHGVEVVLAHLEAAR-TVAHHGGLYHTNAEVKLQG-F-QARPELLEVFSTE
FQMRLLWGSQGASSNQARRYEKFDKVLTALSHKLEPAVRSSEL-------------------------------------
--------------------------------------------------------------------------------
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------------------------------------------
>Felis_catus_SH2D3C
----------------------------------------------------------------------MTEGPKKAS-
RKFKFFKFKGLGSLSNLPRSFTLKRSSASISIRSHLE----------RDTFEATQDDMMTVPQSPPAYARSSDMYSHMGT
MPRHSTKKARDQQATRETKEVG----------------------------------------------------------
-----------SESHLLPQDLPNPPGLEASKEVVVGTNAPLEDTPAVGPNP----SVMGPVGEPEDPSADRKEETAPRNV
PPERAAGEPEAGGDYVKFSKEKYILD------SSPEK-LHKELEEELK-LSSTD----------LRSHAWYHGRIPR---
EVSETLVQRNGDFLIRDSLT----SLGDYVLTCRWRNQ-ALHFKINK-VVVKA---GESYTHIQYLFEQESFDHVPALVR
YHVGSRKAVSEQSGAIIYCPVNRTFPLRYLEACYGLGQGS-------GKAAGPASPSGPKGSHMK-----RRSVTMTD--
------------GLTADKVTRS--------------DGCPTS----TSLPHPRESIR--------NCALSMDQIPDLHS-
------------------------PMSPISESPSSPAYST-VTRVHAAPAAPSATALPASPVTRRSSEPQLCPGSAPKPP
-GESD--KGPYASPSHTLCKASPSPSLSSYSDP------------------------DSGHYCQLQPPVRGSR-------
------------EWAAAEASSRQA--------RSYGERLKE------------------------LSENGAPEGDWG---
-----RAFTVPIVEATSSFNPATFQSLLIPK-DNRPLEVGLLRKVKELLAEVDARTLARHVTKVDCLVARILGVTKEMQT
-LM---------GVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRG-TMGNM
FSFAAVMGALDMAQIARLEQTWVTLRQRHTEGAILYEKKLKPFLKSLNEGKE---GPPLSNTTFPHVLPLITLLECD---
----------------SAPAEGPEPWGSTEHGVEVILAHLEAAR-TVAHHGGLYHTNAEVKLQG-F-QARPELLEVFSTE
FQMRLLWGSQGASSNQARRYEKFDKVLTALSHKLEPAVRSSEL-------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------
>Bos_taurus_SH2D3C
----------------------------------------------------------------------MTEGTKKAS-
KKFKFFKFKGFGSLSNLPRSFTLRRSLAPNSIRPQVE----------ADTFDATQDDMVTVPKSPPAYARSSDMYSHMGT
MPRPSIKKAQGKQATQKAQEVG----------------------------------------------------------
-----------PEPQVVPRSLPDPPGLEAAEKVVPGTIASREDTPTVGPNPS--AVEVDPTRKPEDARPDTEEGRDPKNV
PSERATAEPEAGGDYVKFSKEKYILD------SSPEK-LHKELEEELK-LSSTD----------LRSHAWYHGRIPR---
EVSETLVQRNGDFLIRDSLT----SLGDYVLTCRWRNQ-ALHFKINK-VVVKA---GESYTHIQYLFEQESFDHVPALVR
YHVGSRKAVSEQSGAIIYCPVNRTFPLRYLEACYGLGQGG-------GKAASPASPSGPKGSHMK-----RRSVTMTD--
------------GLTADKVTRS--------------DGCPTS----TSLPHPRESIR--------NCALSMDQIQDLHS-
------------------------PMSPISESPSSPAYST-VTRVHAAPAAPSATALPASPVTRRSSEPQLCPGSVPKPH
-GESD--KGPYSSPSHTLCKASPSPSLSSYSDP------------------------DSGHYCQLQPPVRGSR-------
------------EWAAAEASGRQA--------RSYGEKLKE------------------------LSENGASEGDWG---
-----RTFTVPVVEATSSFNPATFQSLLIPK-DNRPLEVGLLRKVKELLAEVDARTLARHVTKVDCLVARILGVTKEMQT
-LM---------GVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAMDILGCTGSAEERAALLHKTIQLAAELRG-TMGNM
FSFAAVMGALDMAQIARLEQTWVTLRQRHTEGAILYEKTLKPFLKSLNEGKE---GPPLSNTTFPHILPLITLLECD---
----------------SAPAEGPEPWGSTEHGVEVVLAHLEAAR-TVAHHGGLYHTNAEVKLQG-F-QARPELLEVFSTE
FQMRLLWGSQGASSSQARRYEKFDKVLTALSHKLEPAIRSSEL-------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------
>Gallus_gallus_SH2D3C
----------------------------------------------------------------------MAEGQKRGGF
KKFKFFKFKGFESLSSIPRSFTLRRVSVVPSSPESLGMCLPPPQGFLEEAFDSTQDDLNTMPKGPGPYARSSDMYSHMGT
MPRLSFGKVGKSLGKARGTQS-------------------------------------------CREKGSSRDKIP----
-----------STAPRSPGAEKARMDQEIPGNSPSPGMEAPSPSLAPSPS-------AASGAETTDGDFQEKGQERPSES
SPDSHHDGLESSSEYVKFSKEKYILD------SSPEK-LHKELEEELK-LSSTD----------LRSHAWYHGRIPR---
EVSESLVQRNGDFLIRDSLT----SVGDYVLTCRWRNE-PLHFKINK-VTVKS---SDGRTRVQYLFEQESFDNVPALVR
FYVGNRKAISEQSGAIVYCPINRTFPLRYLEASYGLANG--------KHGGSHSPAS-QKGGHIK-----RRSITMTD--
------------GLTADKITRA--------------EGCSTS----VSLPHHRDIIR--------NCAVSVDQIQDLHS-
------------------------PMSPISENPTSPAYST-VTRLKPHACQAAG-IAPASPVIRRSSEPQLCPGSSNKPL
PDPAH---STHSTPCHGYARASPSPSVNSYSDP------------------------DTGHYCQLHPTSPSSR-------
------------ERPAHDTKQLPA--------KSYVERLKVEEGQRGTVE---N--------GSGEAEGGQRLKGERD--
----FVGFVPPTVETCSSFNPAAFQSLLIPL-ENKPLEMAVLKKVKELVADADAKTLAKHITKVDCVVARILGVSAEMQR
-LM---------GVSSGMELLTLPHGHQLRLDLLERFHTMSIMIAVDILGCTGSTEERAALLHKTIQLAAELKS-TMGNM
FSFAAVMNALEMAQIARLEQTWMVLRQRHTEGAILYEKKLKPFLKSLNEGKE---GPPLTNTTFPHVMPLVTLLERD---
----------------DALVDSPEPWEATDNGVEVVMAHLEAAR-MVAHHGGLYHTNAEVKLQG-F-QGRAELLEIFSTE
FQLRLLWGSRGAESSQAERYEKFDKVLTALSHKLEPAVRFSEL-------------------------------------
--------------------------------------------------------------------------------
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------------------------------------------
>Taeniopygia_gu