>Homo_sapiens_KDM4A
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MASESETLNP-------------------------------------------------------SARIMTFYPTMEEFR
NFSRYIAYIESQGAHRAG--------------------------------------------------------------
---------LAKVV------------------------------------------------------------------
-------------------PPKEWKPRA-------------------------------------SYDD-----------
------------------------------------------------------------IDDLVIPAPIQQLVTGQS--
-----------GLFTQYNIQKKAMTVREFRKIANSD---KYCTPRYSE-FEELERKYWKNLT---FNPPIYG-ADVNGTL
Y-----------------EKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFG
EPKSWY---SVPPEHGKRLERLAKGFFPGS---AQSCEAFLRHKMTLISPLMLKK-YGIPFDKVTQEAGE-FMITFPYGY
HAGFN-HGFNCAESTNFATRRWIEYGKQAVL--CSCRKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLPTPEAAE
FLKESE-----------LPPRAGNEEECPEED----------------MEGVEDGEEGDLKTS------LAKHRIGTK--
-----------------------------RHRVCLEIPQEVSQSELFPKED---------------------LSSEQYEM
TECPAA------LAPVRPTHSSV---------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------RQVEDG--------------------------------
--------------------------------------------------------------------------------
---------LTFPDYS-----------------------------------------------------DSTEVKFEELK
NVKLEEEDEEEEQA---AAALDLSVN------------------------------------------------------
----PASVGGRLVFSGSKK-----------------------------------------------KSSSSLGSGSS---
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-----------------------------RDSISSDSETSE---------------------------------------
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--------------------------------------------------------------PLSCRAQ-----------
---------------GQTGVLTVHSYAK---------GDGRVTVGEPCTRKKGSAARSFSERELAEV-------------
ADEYMFSLEENKKSK----------------GRRQPLSKLPR--HHPLVLQECVSDDETSEQLTPEEE---------AEE
TEAWAKPLSQL---WQNRPPN-------------------------FEAEKEFNETMAQQAPHCAVCMIFQTYHQVE---
-------FGGFNQNCGNASDLAPQKQRTKPLIPEMCFTSTGCS----TDINLSTPYLEEDGTSILVSCKKCSVRVHASCY
GVPPA---------KASEDWMCSRCS----ANALEEDCCLCSLRGGALQR-ANDD-------------------------
-----------------------RWVHVSCAVA----------ILEARFVNIAERSPVDVSKIPLPRFK-----------
---------LKCIFCKKR-RK-RTAGCCVQCSHGR-CPTAFHVSCAQAAGVMMQPDDWPFVVFITCFRHK-----IPNLE
R-AKGALQ-SITAGQKVISKHKNGRFYQCEVVRLTT--------------ETFYEVNFDDGS----------------FS
DNLYPEDIVS-QDCLQFGPPAEGEVVQVRWTDGQVYGAKFVAS--------HPIQMYQVEFEDG-SQLVVKRDDVYTLDE
ELPKRVKSRLS--VASDMRFNEIFTEKEVKQEK-KRQRVINSRYREDYIEPALYRAIME---------------------
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>Pan_troglodytes_KDM4A
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MASESETLNP-------------------------------------------------------SARIMTFYPTMEEFR
NFSRYIAYIESQGAHRAG--------------------------------------------------------------
---------LAKVV------------------------------------------------------------------
-------------------PPKEWKPRA-------------------------------------SYDD-----------
------------------------------------------------------------IDDLVIPAPIQQLVTGQS--
-----------GLFTQYNIQKKAMTVREFRKIANSD---KYCTPRYSE-FEELERKYWKNLT---FNPPIYG-ADVNGTL
Y-----------------EKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHKEDMDLYSINYLHC-
-------------------------FFPGS---AQSCEAFLRHKMTLISPLMLKK-YGIPFDKVTQEAGE-FMITFPYGY
HAGFN-HGFNCAESTNFATRRWIEYGKQAVL--CSCRKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLPTPEAAE
FLKESE-----------LPPRAGNEEECPEED----------------MEGVEDGEEGDLKTS------LAKHRIGTK--
-----------------------------RHRVCLEIPQEVSQSELFPKED---------------------LSSEQYEM
TECPAA------LAPVRPTHSSV---------------------------------------------------------
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------------------------------------------RQVEDG--------------------------------
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---------LTFPDYS-----------------------------------------------------DSTEVKFEELK
NVKLEEEDEEEEEE---AAALDLSVN------------------------------------------------------
----PASVGGRLVFSGSKK-----------------------------------------------KSSSSLGSGSS---
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-----------------------------RDSISSDSETSE---------------------------------------
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--------------------------------------------------------------PLSCRAQ-----------
---------------GQTGVLTVHSYAK---------GDGRVTVGEPCMRKKGSAARSFSERELAEV-------------
ADEYMFSLEENKKSK----------------GRRQPLSKLPR--HHPLVLQECVSDDETSEQLTPEEE---------AEE
TEAWAKPLSQL---WQNRPPN-------------------------FEAEKEFNETMAQQAPHCAVCMIFQTYHQVE---
-------FGGFNQNCGNASDLAPQKQRTKPLIPEMCFTSTGCS----TDINLSTPYLEEDGTSILVSCKKCSVRVHASCY
GVPPA---------KASEDWMCSRCS----ANALEEDCCLCSLRGGALQR-ANDD-------------------------
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----------KCIFCKKR-RK-RTAGCCVQCSHGR-CPTAFHVSCAQAAGVMMQPDDWPFVVFITCFRHK-----IPNLE
R-AKGALQ-SITAGQKVISKHKNGRFYQCEVVRLTT--------------ETFYEVNFDDGS----------------FS
DNLYPEDIVS-QDCLQFGPPAEGEVVQVRWTDGQVYGAKFVAS--------HPIQMYQVEFEDG-SQLVVKRDDVYTLDE
ELPKRVKSRLS--VASDMRFNEIFTEKEVKQEK-KRQRVINSRYREDYIEPALYRAIME---------------------
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>Mus_musculus_KDM4A
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MASESETLNP-------------------------------------------------------SARIMTFYPTMEEFR
NFSRYIAYIESQGAHRAG--------------------------------------------------------------
---------LAKVV------------------------------------------------------------------
-------------------PPKEWKPRT-------------------------------------SYDD-----------
------------------------------------------------------------IDDLVIPAPIQQLVTGQS--
-----------GLFTQYNIQKKAMTVREFRKIANSD---KYCTPRYSE-FEELERKYWKNLT---FNPPIYG-ADVNGTL
Y-----------------EQHVDEWNIGRLKTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFG
EPKSWY---SVPPEHGKRLERLAKGFFPGS---AQSCEAFLRHKMTLISPLMLKK-YGIPFDKVTQEAGE-FMITFPYGY
HAGFN-HGFNCAESTNFATRRWIEYGKQAVL--CSCRKDMVKISMDVFVRRFQPERYKLWKAGKDSMVIDHTLPTPEAAE
FLKDSGG----------LTPRAGSEE-CPEED----------------VEAADQGEEGDVKRS------LAKHRIGTK--
-----------------------------RHRVCLEIPQEVSQSELFPKEE---------------------LSSGQYEM
TECPAT------LAPVRPTHSSV---------------------------------------------------------
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------------------------------------------RQVEDS--------------------------------
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---------LPFPDYS-----------------------------------------------------DPTEVKFEELK
NVKLEEEDEEDEPE---AAALDLSVN------------------------------------------------------
----PASVGGRLVFSGSKK-----------------------------------------------KSSSSLGSTSS---
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-----------------------------QDSVSSDSETAE---------------------------------------
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--------------------------------------------------------------SVSCQGQ-----------
---------------EKTGVLTVHSYAR---------GDGKAATGEPSVKKKRSAPRSISEQELAEV-------------
ADEYMLSLEENKKTK----------------GRRQPLSKLPR--HHPLVLQECGSDDETSEQLTPEEE---------AEE
TEAWAKPLSQL---WQNRPPN-------------------------FEAEKEFNEIMAQQAPHCAVCMIFQTYHQVE---
-------FGAFSQSCGDASEPAAQTQRTKPLIPEMCFTTTGCS----TDINLSTPYLEEDGTSMLVSCKKCSVRVHASCY
GVPPA---------KASEEWMCSRCS----ANALEEDCCLCSLRGGALQR-ANDD-------------------------
-----------------------RWVHVSCAVA----------ILEARFVNIAERSPVDVSKIPLPRFK-----------
---------LKCVFCKKR-RK-RNAGCCVQCSHGR-CPTAFHVSCAQAAGVMMQPDDWPFVVFITCFRHK-----IPNLE
R-AKGALL-SITAGQKVISKHKNGRFYQCEVVRLTT--------------ETFYEVNFDDGS----------------FS
DNLYPEDIVS-QDCLQLGPPAEGEVVQVRWTDGQVYGAKFVAS--------HPIQMYQVEFEDG-SQLVVKRDDVYTLDE
ELPKRVKSRLS--VASDMRFNEIFTEKEVKQEK-KRQRVINSRYREDYIEPALYRAIME---------------------
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>Canis_familiaris_KDM4A
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MASESETLNP-------------------------------------------------------SARIMTFYPTMEEFR
NFSRYMAYIESQGAHRAG--------------------------------------------------------------
---------LAKVV------------------------------------------------------------------
-------------------PPKEWKPRA-------------------------------------SYDD-----------
------------------------------------------------------------IDDLVIPAPIQQLVTGQS--
-----------GLFTQYNIQKKAMTVREFRKIANSD---KYCTPRYSE-FEELERKYWKNLT---FNPPIYG-ADVNGTL
Y-----------------EKHVDEWNIGRLKTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFG
EPKSWY---SVPPEHGKRLERLAKGFFPGS---AQSCEAFLRHKMTLISPLMLKK-YGIPFDKVTQEAGE-FMITFPYGY
HAGFN-HGFNCAESTNFATRRWIEYGKQAVL--CSCRKDMVKISMDVFVRKFQPERYKLWKAGKDSTVIDHTLPTPEAAE
FLKESE-----------LAPRARNEE-CPEEDD---------------MEGLEDGEEGDFKRS------LAKHRIGTK--
-----------------------------RHRVCLEIPQEVSQSELFPKEE---------------------LSTGQYDM
TECQAA------LAPVRPTHSSV---------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------RQVEDN--------------------------------
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---------LPFPDYS-----------------------------------------------------DSSEVKFEELK
NVKLEEEDEEEEEE-QEAAALDLSVN------------------------------------------------------
----PASIGGRLVLSGSKK-----------------------------------------------KSSSSLGSSSS---
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-----------------------------RDSISSDSETSE---------------------------------------
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--------------------------------------------------------------PLSCRAQ-----------
---------------GQSGVLTVHSYAK---------GDGRVVMGEPCTRKKGGATGSISERELAEV-------------
ADEYMFSLEENKKSK----------------GRRQPLSKLPR--HHPLVLQDCVSDDESSEQLTPEEE---------AEE
TEAWAKPLSQL---WQNRPPN-------------------------FEAEKEFNETMAQQAPHCAVCMIFQTYHQVE---
-------FGGLSQSCGNTSALAPQKQRTKPLIPEMCFTSTGCS----TDINLSTPYLEEDGTSLLVSCKKCSVRVHASCY
GVPPT---------KASEDWMCSRCS----ANALEEDCCLCSLRGGALQR-ANDD-------------------------
-----------------------RWVHVSCAVA----------ILEARFVNIAERSPVDVSKIPLPRFK-----------
---------LKCVFCKKR-RK-RTAGCCVQCSHGR-CPTAFHVSCAQAAGVMMQPDDWPFVVFITCFRHK-----IPNLE
R-AKGALQ-SITAGQKVISKHKNGRFYQCEVVRLTT--------------ETFYEVNFDDGS----------------FS
DNLYPEDIVS-QDCLQLGPPAEGEVVQVRWTDGQVYGAKFVAS--------HPIQMYQVEFEDG-SQLVVKRDDVYTLDE
ELPKRVKSRLS--VASDMRFNEIFTEKEVKQEK-KRQRVINSRYREDYIEPALYRAIME---------------------
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>Gallus_gallus_KDM4A
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MASELESLNP-------------------------------------------------------SARIMTFRPTMEQFR
DFSRYIAYVEAQGAHRAG--------------------------------------------------------------
---------LAKVR------------------------------------------------------------------
-------------------RGEAGPERK-------------------------------------CYDD-----------
------------------------------------------------------------IDELVIPAPIQQVVTGQS--
-----------GLFTQYNIQKKAMTVREFRRIANSD---KYCTPRYTD-FEDLERKYWKNLT---FNAPIYG-ADVNGTL
Y-----------------DKHVDAWNIGRLNTILDVVENESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFG
EPKSWY---SIPPEHGKRLERLAKGFFPGS---AQSCEAFLRHKMTLISPSILKK-YGIPFDKVTQEAGE-FMITFPYSY
HAGFN-HGFNCAESTNFATLRWIEYGKQSVL--CSCRKDMVKISMDVFVRKYQPDRYKLWKAGKDVTVIDHALPTPEAAE
FLKGDL------------MQKVKSGRQYAEDMET--------------GEACKEEVDGDETKS------VPKHRIGTK--
-----------------------------RHRVCLEVPQEVSESEAFPKEE---------------------LSSMQDEE
DAAEPC---------ERATGEVT---------------------------------------------------------
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------------------------------------------QQSEQG--------------------------------
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---------HKVPVTSY----------------------------------------------------RVGMAKSEELK
VVKLE-EEEEEEQE---AAVLDLSIS------------------------------------------------------
-----HASNSASVLPTSKQ-----------------------------------------------RAPSSVQPSSP---
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-----------------------------AYSGSSDSESTD---------------------------------------
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--------------------------------------------------------------LLPKRTLP----------
---------------GPAGVLTVHSYAR---------GDASGSDNE-TSGKKASATGSVNEQELAEV-------------
TKEYIQSMKESKKSK----------------GRRQPLSKLPR--HHPLLVKDCISDDEASEQLTPEEE---------AEE
TEAWAKPLSQL---WQNRPPN-------------------------FEAEKEYNRTMAQQSPYCAVCMLFQTY-QAE---
-------CGGSSQNSGGTPGAADGKIRTKPLIPEMCFTTTGCS----TDLNLSTPYLEEDGTSVLITCRNCQVCVHASCY
GVSPD---------KATEDWMCSRCT----ENALEEDCCLCSLRGGALQR-ANDD-------------------------
-----------------------KWVHVMCAVG----------VLEAKFVNIAERSPVDVSKIPLQRFR-----------
---------LKCIFCKKR-RK-RIAGCCVQCSHGR-CPTSFHVSCAQAAGVMMQPDDWPFVVFITCFRHK-----IPSQA
ERAKAALQ-DLSPGQIVISKHKNGRFYQCEVVSLAK--------------ETFYEVNFDDGS----------------FS
DNLYPEDIVS-RDCLQLGPPAEGEVVQVRWTDGQVYGAKFVAS--------HAIQMYQVEFEDG-SQLMVKRDDVYTLEE
ELPKRVKSRLS--IASDMRFTEIFAEKEVRQER-KRQRVINSRYREDYIEPALYRAIME---------------------
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>Anolis_carolinensis_KDM4A
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MASELENLNP-------------------------------------------------------SARIMTFHPTMEEFK
NFSRYIAYIESQGAHRAG--------------------------------------------------------------
---------LAKVV------------------------------------------------------------------
-------------------PPKEWKPRR-------------------------------------WYDD-----------
------------------------------------------------------------IDDVIIPAPIQQVVTGQS--
-----------GLFTQYNIQKKAMTVREFRRIANSD---KYCTPRYTD-FEDLERKYWKNLT---FNAPIYG-ADVNGTL
Y-----------------DKHVDDWNIGHLNTILDVVENESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFG
EPKSWY---CVPPEHGKRLERLAKGFFPGS---AQNCEAFLRHKMTLISPSILKK-YGIPFDKVTQEAGE-FMITFPYGY
HAGFN-HGFNCAESTNFATLRWIEYGKQSVL--CSCRKDMVKISMDVFVRKYQPDRYKLWKAGKDVTVIDHALPTPEAAE
FFKGEL------------LQKVKNEKHCPDDTEL--------------EEECSADG-DIEKKS------MPKHRIGTK--
-----------------------------RHRVCLEVPHEVSQSEAFPKEE---------------------LGPVQFEM
DVAESP---------VGPAREPV---------------------------------------------------------
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------------------------------------------QQGEQG--------------------------------
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---------IALPEYG-----------------------------------------------------DSSEVKFEELK
NVKLD-DEEE-EPE---AAVLDLSIS------------------------------------------------------
-----HSVTST---GIKLQ-----------------------------------------------SSVSSLQSDSP---
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-----------------------------MGSGSSDSEPSD---------------------------------------
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--------------------------------------------------------------LYRQDLE-----------
----------------QPEVLMVHSYAK---------EEVNDMSSERPSGKKASATTRVNEQDLAKM-------------
AKEYIRSVKDHKKSK----------------GRRQPLSKLPR--HHPLLVKDGLSDDEMSEQLNPEEE---------AEE
TEAWAKPLGQL---WQNRPPN-------------------------FEAEKEYNAAMAQQAPYCAVCMLFQTY-QAD---
-------CGG--QSSQVVLDAG-GKMRTKPLIPEMCFTTTGCS----TDVSLSTPYLEEDGTSLLVTCKRCRVRVHASCY
GVAPE---------KATGDWKCSRCR----ANALEEDCCLCSLRGGALQR-ANGN-------------------------
-----------------------KWVHVMCAVA----------VLEAKFVNIAERSPVDVSKIPLQRFR-----------
---------LKCVFCKKR-RK-RTAGCCMQCSHGR-CPTSFHVSCAQAAGVMMQPDDWPFVVFTTCFRHK-----IPSQA
ER---ALQ-DLVVGQAVISKHKNGRFYQCEVINLTK--------------ETFYEVNFDDGS----------------FS
DNLYPEDIVS-RDCAQLGPPAAGEVVQVRWTDGQIYGATFVAS--------HVIQMYQVEFEDG-SQLMAKRDDVYTLNE
ELPKRVKSRLS--VASDMRFTEIFTEKEVKQER-KRQRVINSRYREDYIEPALYRAIME---------------------
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>Pelodiscus_sinensis_KDM4A
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-----------------------MTVREFRRIANSD---KYCTPRYTD-FEDLERKYWKNLT---FNAPIYG-ADVNGTL
Y-----------------EKHVHEWNIGKLNTILDVVENESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFG
EPKSWY---SVPPEHGKRLERLAKGFFPGS---AQSCEAFLRHKMTLISPSILKK-YGIPFDKVTQEAGE-FMITFPYGY
HAGFN-HGFNCAESTNFATLRWIEYGKQSVL--CSCRKDMVKISMDVFVRKYQPDRYKLWKAGKDVVPIDHTLPTPEAAE
FFKGEL------------LQKVKNGKPSTEEPET--------------GEACQEGVDVDEKKS------LPKHRIGAK--
-----------------------------RHRVCLEVPHEVSQSEAFPKEE---------------------LSPVQYEV
EVAAPP---------VRPASERV---------------------------------------------------------
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------------------------------------------QQGEDG--------------------------------
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---------LPGSD-EV----------------------------------------------------DSSEVKFEELK
PVKLE-EEEEDEQE---VAVLDLSVP------------------------------------------------------
-----HSVSSTSALAVSMQ-----------------------------------------------NPVFSLQPSSP---
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-----------------------------AYSASSDSESAE---------------------------------------
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--------------------------------------------------------------LLPRRTL-----------
---------------GQAGVLTVHSYAR---------GDAAGPGGDHASGKKASVN----EQELAEV-------------
AKEYMRSVKESKKSK----------------GRRQPLSKLPR--HHPLVVKDYISDDEMSEQLTPEEE---------AEE
TEAWAKPLSQL---WQNRPPN-------------------------FEAEKEYNESMAQQPPYCAVCMLFQTY-QAE---
-------CGGHGQSAAVAPSAATRKVRTKPLIPEMCFTATGCS----TDLNLSTPYLEEDGTSVLITCKTCSVCVHASCY
GVSPE---------KATEDWTCSRCT----ANALEEDCCLCSLRGGALQR-ANDD-------------------------
-----------------------KWVHVMCAVA----------VLEAKFVNIAERSPVDVGKIPLQRFR-----------
---------LKCVFCKKR-RK-RIAGCCVQCSHGR-CPTSFHVSCAQAAGVMMQPDDWPFVVFITCFRHK-----IPSQA
ERAKAALQ-DLSAGQMVISKHKNGRFYQCEVVSLTK--------------ETFYEVNFDDGS----------------FS
DNLYPEDIV-------------------------VCGVTGALL--------H----------------------------
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>Danio_rerio_KDM4A_a
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MAS----DMP------------------------------------------------------VSRGIMTFHPTVEEFK
NFSRYIAYMESQGAHKAG--------------------------------------------------------------
---------LAKIV------------------------------------------------------------------
-------------------PPKNWKPRG-------------------------------------SYDD-----------
------------------------------------------------------------IDDLIIPAPIQQVVTGQS--
-----------GLFTQYNIQKKAMTVKEFRKTANSD---KFCSPRYDD-FEELERKYWKNVT---FNPPIYG-ADVNGTL
Y-----------------DPDIKEWNVGHLNTILDTVEHESGITIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFG
EPKSWY---TVPPEHGKRLERLAKGFFPGS---SQNCEAFLRHKMTLISPSILKK-YGIPFEKITQEAGE-FMVTFPYGY
HAGFN-HGFNCAESTNFATRRWIDYGKQAIL--CSCRKDMVKISMDVFVKKFQPERYELWLEGKDNAPIDHSKPTPEAAE
FLGGEA------------GAQELRIE------------------------NQSNEGQKKSLA---------KQRIGTK--
-----------------------------RHRVCLDFPEEVLPKTETND------------------------EAEYGKK
GRLTPYT-----------EQCKE---------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------YTELKH--------------------------------
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---------EDRTLPLM----------------------------------------------------GSTSLKMLPGS
RSAEFSENVRGAGFSDADLDAKATSH------------------------------------------------------
---ISACAQPFPKHHLSIA----------------------------------------------SVPTVPHCLSAVPRV
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-----------------------------STKPGVASLLFH---------------------------------------
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-------------------------------------------------------------RTLSP--------------
-----------------TDALQVHSYAA---------KAALCKPQTPSPEKPREDLHIPDISLDVRP-------------
NTPTPPPDTPEHEIEGEKENNS-------MKRKLQPLSKLPR--LHPLLRENSSDDE-IQEPTAEPE------------E
TDPWAKILAPM---WQSRQRN-------------------------FQIEKEFNFRMGLHPPYCAVCSLFHTYNES----
-----DVISLG-GFAAVGGNP----QRTKPLIPEMCFTSSS-------EGHLSTPNLEADGTSQLISCSVCSVRVHTSCY
GVSQD---------AKLDSWRCSRCE----ANAITQDCCLCSLRGGALQR-ANND-------------------------
-----------------------KWVHVLCAVA----------VLEARFVNIAERRPVDLSTIPFQRFK-----------
---------LKCQFCRKW-VK-KTTGCCVQCSHGR-CSTSFHATCAQAAGVQMHPDDWPFVVYFTCWRHK-----GGTHI
ERNMASMR-ELEKGQKVICKHKNGRYYHCEVVELTK--------------ATFYEVIFDDGS----------------FS
DNLFPEDIVN-RDCTRHGPPSEGEVVQVQWTDGLIYGAKFVSD--------HIIPMYQVEFEDD-SQLTVKREDVFSLDE
ELPKRVKSRLS--VASDMRFKGVFVEKEVKQDS-KRQRVINSRYREDYIEPAIYRAILE---------------------
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>Danio_rerio_KDM4A_b
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MASDSVSQSSQ----------------------------------------------------SPATRIMTFHPTKEEFK
DFNRYIAYMESQGAHRAG--------------------------------------------------------------
---------MAKVV------------------------------------------------------------------
-------------------PPKDWKPRR-------------------------------------TYDD-----------
------------------------------------------------------------IEDLVIPTPIQQVVTGQS--
-----------GLFTQYNIQKKPMTVREFRKTANTD---KFSNPRYAD-FEELERKFWKNLT---FNPPLYG-ADVSGTL
Y-----------------DPDVMEWNIGRLNTILDMVERESGITIKGVNTPYLYFGMWKSTFAWHTEDMDLYSINYLHFG
EPKSWY---VVPPEHGKRLERLAKGFFPGS---AQSCEAFLRHKMTLISPSILRK-YGIPFEKVTQEAGQ-FIVTFPYGY
HAGFN-HGFNCAESTNFATQRWIDYGKLATL--CSCRKDMVKISMDVFVHKFQPERYKLWKAGKDNVPIDHSKPTPEVAE
IQKENEKGEISDS----ERAETLEERGEAEAGDQ--------------QKANTDDGEEDKAEAFSEKVVKRESDAGKEKA
EAEVEKSV---------------------RDEEPSSTSEQISSSSPKQNTGQKRLRSSTDNEAKDDNQVKIEVEEVEKKK
AKLGQNETDNNEEQSVSAEPDDE---------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------KAEETM--------------------------------
--------------------------------------------------------------------------------
---------ETDTPPPQ----------------------------------------------------QQECMEAELST
SDPTSSSDITTQQREEESSDVTSSTQSINSVDEDVALGGDVASQSEDVTQSFVVQINPEDITPTDLTDAQPSNITSHPCS
SDIPATSFMSVSSSNFSKHSISFAYTCDGTTEPSDSINLTPRVPSINVAHISDVQPEPSDIIVSLKQNSSANSTYTSDVQ
SDLSNVTVDPEHKPSINSTHIINVQSETSNITISSEHEPSISSTPMSDVQSETSFKYEPGNNSAYVCDVKPEHSDISMSP
IYKPGVNFAHTSDVQPEPSECESCTNSDHICDVQSEANDIIINSKDEMSINSAHTFDVQPEPSDNTVSLTHKPDISSTSG
SDVPSGPGDITDSLGYDPDFNSTHTGHVQSESNNSPKHKLPINSAHTYDVQSGPSDITDGHRFESEFNSTHICDVQSGPS
DMSVNSKRKSSIDSAQIDDAQSDPSDISIGSKQEYSINSAQIDNVQSEPSDISIGSKQESSINSAQIDNVQSEPSNISIS
SKQETSINSTQIDDVQSEPSDISISSKNKLRINSAQIDDVQSAPSGISVSSEQETSIISAQVDDVQSEYSDISISSKHEP
SINSTQTDDIQSEPIDISFGSKQESCINSAQMYDVQSEPSDISISSTQETSINSAQMYDVQLEPSDISISFKDKPSINSS
QVDDVQSEPSDICFGSEQETCINSAQIYDVQSEPSNISFSSKQETSINSTQMYDVQSEPSDISISSNQETSINSTQMYDV
QSEPSDISISSNQETSINSTQMYDVQSEPSDISISSNQETSINSTQMHDVQSEPSDISISSNQETTINSTQMYDVQSDPS
DISISSKHKPSINSARMYDVQSEPSDISISSKHNPSIDSTQMFDVQSEPSDFSISSKHKPSIDSTQIYDVQSAPSGLTIS
YKQKTSINSAQMYEVQSEPSDFSVSSKRKPSIDSIHMYDDVQLKSSNFMVSRTPEPTYKIIPEPSSSVSVNVSGLSSVLA
SVSQGSVQHIFQRTLSPAEVLHVHSYAK---------GDYSDIEPRIQHER-DSDSD-----------------------
-SESQDDNKKEAERP---------------AEAQYRLPRLPR--HHPLIKDSISDEE-LQDQAASEED---------GLD
GEAWARPLTQL---WQNRPYN-------------------------PDREREYNREMGLRPPYCSICMLFQAHHR-----
-------SEGAES-EPAVVLR-GGQMRTKPLIPERCFTITTEES---ADVQPSTAHLEEDGTSLLISCSLCSVRVHTSCY
GVASG---------RVSKDWKCARCK----ANAFAESCCLCSLRGGALHR-ANNG-------------------------
-----------------------KWVHVLCAVA----------VQEARFVNITERSPVDLSGIPLQRFK-----------
---------LKCYYCKRR-MK-KTLGCCVQCSHGR-CPTSYHPTCAQAAGVIMHPDDWPFVVYVTCCRHK-----GPVQS
ERNKSAMR-ELSVGQRVICKHKNGRYYQCEVIQLTK--------------ETFYEVNFDDGS----------------FS
DNLFPEDIVN-RDCAQLGPPPQGEVVQVRWTDGLVYGAKFVAA--------HVIQMYQVEFEDG-SLLTAKRDDVYTLDE
ELPKRVKSRLS--KASDMRFDGMFGEK-KVQES-KRQRVINSRYRGDYIEPVIYRAIME---------------------
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>Takifugu_rubripes_KDM4A_b
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MTTDTPSQS-------------------------------------------------------VGSRVMTFTPSKEEFK
DFNQYIAYMESQGAHRAG--------------------------------------------------------------
---------MARVI------------------------------------------------------------------
-------------------PPKGWKPRK-------------------------------------TYDD-----------
------------------------------------------------------------IDDLVIPAPIQQVVTGQS--
-----------GLFTQYNIQKKPMTVKEFRKTSNMD---KFCNPRYAD-FDELERKFWKNLT---FNPPLYG-ADVSGTL
Y-----------------DADVTEWNIGHLKTILDTVENESGIKIKGVNTPYLYFGMWKSAFAWHTEDMDLYSINFLHFG
EPKSWY---IVPPEHGKRLERLAKGFFPGN---AQSCEAFLRHKMTLISPSILKK-YSIPFEKVTQEAGQ-FIVTFPFGY
HAGFN-HGFNCAESTNFATQRWIDYGKQATL--CSCRQDMVKISMDVFVLKYQPDRYKLWKAGKDNTAIDHSKPTPEAAK
FLQDN-------------KSQS-----PAEDEPE--------------VTSSTQEEPCFHPP---LPCFSSKPQAGTK--
-----------------------------RQLDAIKVCEEVKVDPTMNSS-----------------------TEVEPKR
AKVSTQE---------SPSKPPD---------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------KPDTDI--------------------------------
--------------------------------------------------------------------------------
---------ETAARFCY----------------------------------------------------VHLGLL--LLF
LDK---RNVLPEPKTEKRTKLEPKPQ------------------------------------------------------
----PKVSSRKTTNSPSKK----------------------------------------------DKNSSTSTCETREAA
ERRV----------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------ASEEATSPDKCQ----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------PSSRFN-----------
-------------------VLHVHSYAK---------GDYGE--GEIQSKE-DRSERRVFRELALIH-------------
TSSLQQG-AEEATTD---------------KEAEGDLGQLPG--HHPLIKDGMSDEETPQEPSIAEEG---------CLD
GESWAKPLAHL---WQDKPAN-------------------------LKKEREYNQRMCSRPPYCSICTLFHTHQQ-----
-------TKCRTTGESPVVVD-RGRMRTKPLIPEMCFATTTEEDSE-SEKPPATPYLEEDGTSLLISCSTCSIRVHSSCY
GVDPA---------TVSKDWKCVRCK----ANAMTENCCLCSLRGGALQK-ANNN-------------------------
-----------------------KWVHVLCAVA----------VLEARFVNVTERSPVDLSGIPLQRFK-----------
---------LKCYYCKKR-MK-KASGCCVQCSHGR-CPTAYHPTCAQAAGVLMRPDEWPFVVHVTCCRHK-----SPTQI
ERNKAAMN-ELTVGQKVICKHKNGRYYQCDVVQLSK--------------ETFYEVNFDDGS----------------FS
DNLFPEDIVN-RDCAQLGPPPQGEVVQVRWTDGLVYGAKFVAA--------HAVHMYLVEFEDG-SQLTAKRDDVYTLDE
ELPKRVKSRLS--KASDMRFDGIFEEREIIQDS-KRQRVINSRYRGDYIEPVIYRAIME---------------------
--------------------------------------------------------------------------------
-------------------------------------
>Tetraodon_nigroviridis_KDM4A_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
MTTDTPCPS-------------------------------------------------------VASRVMTFTPSKEEFK
DFNQYIAYMEAQGAHRAG--------------------------------------------------------------
---------MARVI------------------------------------------------------------------
-------------------PPKGWKPRK-------------------------------------SYDD-----------
------------------------------------------------------------IDDLVIPAPIQQVVTGQS--
-----------GLFTQYNIQKKPMTVKEFRKTSNMD---KFCNPRYAD-FDELERKFWKNLT---FNPPLYG-ADVSGTL
Y-----------------DADVTEWNIGRLNTILDTVETESGIKIKGVNTPYLYFGMWKSAFAWHTEDMDLYSINFLHFG
EPKSWY---IVPPEHGKRLERLAKGFFPGN---AQSCEAFLRHKMTLISPSILKK-YSIPFEKVTQEAGQ-FIVTFPFGY
HAGFN-HGFNCAESTNFATQRWIDYGKQATL--CSCRQDMVKISMDVFVHKYQPERYKLWKAGKDNATIDHSKPTPEAAR
FLTES-------------KSEPSKG--PAEDASE--------------VTGSAREE------------KSSKTSTGTK--
-----------------------------RQLEAIKACEDVKLEPMVNSS-----------------------SEMEPKR
AKISAQG---------SPPQPPG---------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------GADRGT--------------------------------
--------------------------------------------------------------------------------
---------SGVASKRL----------------------------------------------------QGTGLL--FPS
SEP---GNVLPEPKKEKPAKLETKAQ------------------------------------------------------
----LKASLRKTSNSFSKK----------------------------------------------DKSSAAPACEP----
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------SEEVSSPDRCQ----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------PASRCSHEHK-------
---------LFQRTLSPADVLHVHSYAK---------GDYGE--GELQSKE-EKSES---SEIKAER-------------
DKRLGRSQVAEALTD---------------QEPEGDLGQLPG--HHPLIKDGMSDEETPQEPSIAEEG---------CLE
GEGWAKPLAHL---WQDKPAN-------------------------LKKEREYNQRMCSKPPYCSICTLFHTHQQVET--
--SSAARTKCRNSMESPVIMA-GGGMRTKPLIPEMCFATTTEEDSE-SEKPPATPYLEEDGTSLLVSCSNCSIRVHTSCY
GVDPA---------TVSKDWKCARCK----ANAMTENCCLCSLRGGALQK-ANNN-------------------------
-----------------------KWVHVLCAVA----------VLEARFVNITERSPVDLSGIPLQRFK-----------
---------LKCYYCKKR-MK-KASGCCVQCSHGR-CPTAYHPTCAQAAGVLMQPDEWPFVVHVTCCRHK-----SPAQI
ERNKAAMN-ELVVGQKVICKHKNGRYYQCDVVQLSK--------------ETFYEVNFDDGS----------------FS
DNLFPEDIVS-RDCAQLGPPPQGEVVQVRWTDGLVYGAKFVAA--------RAVHMYLVEFEDG-SQLTAKRDDVYTLDE
ELPKRVKSRLS--KASDMRFDGIFEEKEIIQDS-KRQRVINSRYRGDYIEPVIYRAIME---------------------
--------------------------------------------------------------------------------
-------------------------------------
>Gasterosteus_aculeatus_KDM4A_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
MASGVISQNN------------------------------------------------------GSKGIMTFYPTPEEFK
NFSRYIAYVESQGAHKAG--------------------------------------------------------------
---------LAKIV------------------------------------------------------------------
-------------------PPKEWKPRS-------------------------------------SYDD-----------
------------------------------------------------------------IDDLVIPAPIQQVVTGQS--
-----------GLFTQYNIQKKSMTVREFRKIANSD---KFCSPHYDD-FEELERKYWKNVT---FNPPIYG-ADVNGSL
Y-----------------DPDVKDWNICHLDTILDTVEHESGITIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFG
EPKSWY---CVPPEHGKRLERLAKGFFPGS---SQNCEAFLRHKMTLISPSILKK-YGIPFEKITQEAGE-FMVTFPYAY
HAGFN-HGFNCAESTNFATERWIEYGKQAVL--CSCRRDMVKISMDVFVKKFQPDRYEQWLAGRDVLPIDHRRPTPEAKE
FLGESS------------NDTATCGDDGERKREP--------------ADAASLGTPRSALN---------TQRIETK--
-----------------------------RHRVCLEVPDEVVPKDEDEDG-----------------------AEQYGKR
PRLILIP-----------PRTTA---------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------QDGKRN--------------------------------
--------------------------------------------------------------------------------
---------KG----II----------------------------------------------------TFCNYTYISCL
PK------------IDFLSLIKTRAP------------------------------------------------------
---AISSQSQPGNRYLSVS----------------------------------------------ATPSWTEATAQP---
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------ARKMGVASLLFH---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------KTLSS--------------
-----------------KDALQVQSYTM---------EKQQQQHSHTQLQV-HSYARAEGLVEPGRK-------------
EDKPKATSPAEAQAEQVSEEQSYCMSVVEKQQPQAQLCTLPR--HHPLIREAHSDNEEFMDEEFEQE------------E
KEEWAKPLTQL---WQCRPYN-------------------------PEVEREYNKSLGQQAPYCSICLLFYTYHQ-----
-----SESSSGSSSVTLVNRP-GGRQWSKPLIPEMCFNTQSSRSNDNGEGQLSNPHVAEDGTSRLVSCAQCCVRVHTSCY
GVPEDE--------GELDDWLCTRCE----ADATTEDCCLCSLRGGALQR-ANND-------------------------
-----------------------KWVHVLCAIT----------VLEARFVSVTERGPVDLSAIPLPRFK-----------
---------LKCAYCRKR-MKREVKGCCVQCSHGR-CSTAFHPTCAQAAGMIMNPDDWPFTVFITCHRHK-----APGIP
ERNKASMR-ELAVGQRVICKHKNGRYYHSEVVELTT--------------ATFYEVVFDDGS----------------YS
NNLFPEDIQN-RDCVRLGPPTEGDAVQVRWTDGLIYGAKFLVS--------HSIPMYLVEFEDG-SQITVKREDIYTLDE
NLPKRVKSRMS--VASDMRFE-LFSQSNVKQNS-KRQRVINSRYREDYIEPVIYRAIME---------------------
--------------------------------------------------------------------------------
-------------------------------------
>Gasterosteus_aculeatus_KDM4A_b
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
MTTDTPAQS-------------------------------------------------------VGSRIMTFTPTKEEFK
DFSRYIAYMESQGAHKAG--------------------------------------------------------------
---------MSKVI------------------------------------------------------------------
-------------------PPKDWKPRQ-------------------------------------TYND-----------
------------------------------------------------------------IDDLVIPAPIQQVVTGQS--
-----------GLFTQYNIQKKPMTVLEFRKTSNMD---KFCSPRYVD-FDELERKFWKNLT---FNPPLYG-ADVSGTL
Y-----------------DPDVTEWNIGRLNTILDTVENESGIKIKGVNTPYLYFGMWKSAFAWHTEDMDLYSINYLHFG
EPKTWYSRYVVPPEHGKRLERLAKGFFPGN---AQGCEAFLRHKMTLISPSILKK-FGIPFEKVTQEAGQ-FVVTFPFAY
HAGFN-HGFNCAESTNFATQRWIDYGKQATL--CSCRQDMVKISMDVFVRKFQPDRYKLWKAGKDNAAIDHSKVPPEAAE
LPREE-------------KSEPPK---EAESKEP--------------ATPAPEDKSKNPPL---KRLLNPKPQTGTK--
-----------------------------RQLQATEASGDIGVELPVKENE---------------------IEGVEPKK
ARLSRKD---------SPTKVK----------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------PDKGT--------------------------------
--------------------------------------------------------------------------------
---------VQSVKLLL----------------------------------------------------PRWGLKGRLGY
LEVGCIGNFTTHSTGEAAKRYCTINN------------------------------------------------------
----KPSLAGRPEGSQAKS----------------------------------------------PSKSSSKKTSSRQ--
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------SASNTSPAHKL----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------FQTTMS-----------
----------------PADVLHVHSYAK---------GDYKAVGGDTHTHK-CRSST---VAIVEPV-------------
TEGVSLQQVAEESAG---------------EEDLSDLGQLPG--HHPLIKDCLSDEEAPEEAPPAEEG---------GLE
GESWAKPLAHL---WQNRPPN-------------------------LKKERVYNQCMGSKAPYCSICTLFHTYQQ-----
-------TECASSVDSPVMLA-GGRMRTKPLIPEMCFTTTTEEDSE-CDEQPVTPHLEEDGTSLLISCSQCSIRVHTSCY
GVDPA---------SVSKEWKCVRCK----ANAMNENCCLCLLRGGALQK-ANNN-------------------------
-----------------------KWVHVLCAVA----------VLEARFVNITERSPVDLSGIPLQRFK-----------
---------LKCYYCKKR-MK-KASGCCVQCSHGR-CPTAYHPTCAQAAGVLMQPDEWPFVVHVTCCRHK-----GPTQI
ERNKAAMH-ELTVGQKVICKHKNGRYYQCDVVQLSK--------------ETFYEVNFDDGS----------------FS
DNLFPEDIVS-RDCAQLGPPPKGDVVQVRWTDSLVYGAKFVAA--------HAIHMYLVEFEDG-SQLTAKRDDVYALDE
ELPKRVKSRLS--KASDMRFDGIFEGKEIIKQS-KRQRVINSRYRGDYIEPVIYRAIME---------------------
--------------------------------------------------------------------------------
-------------------------------------
>Oryzias_latipes_KDM4A_b
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
MTTDPPVQS-------------------------------------------------------EAFRVMTFTPSKEEFK
DFVRYVAYMESQGAHRAG--------------------------------------------------------------
---------IAKVI------------------------------------------------------------------
-------------------PPKGWKPRR-------------------------------------TYDD-----------
------------------------------------------------------------VDDLLIPAPIQQVVTGQS--
-----------GLFTQYNIQKKPMLVHEFQKTSNLD---KFCSPRFVD-FNELEKKFWKNLT---FNPPLYG-ADISGTL
F-----------------DPDVPDWNISHLDSILNALEGKCDDKIKAAQGPLIDFGMWKSAFAWHTEEMDLYRLSYMHYG
EPRSWY---VVPPEHGRRLEKLAKGFFPGN---AQNCEAFLRHKMTLISPTILKK-YNIPFEKVIQEAGQ-FIVTFPFAY
HAGFN-HGFNCAESTNFATERWIEYGKRATL--CSCRQDSVKISMDAFVHKYQPERYSLWKAGKDHVLIDHSKPTPEAAE
FQRKA-------------DVQPLKESLSKRSAKE--------------PSGRIQYNSGDEPPGGEVSRLTAAPPQKKR--
-----------------------------THKIPLAAASEINTITTYYSS----------------------LTKNSNKV
TECPPPN---------KPLKSEH---------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------RTSREN--------------------------------
--------------------------------------------------------------------------------
---------VVDQSDEP----------------------------------------------------FYSQLTEKKTE
GAESDKSDLMDEDSDTEAAELEATKE------------------------------------------------------
----KGSKQQLQSKVQSKS----------------------------------------------SSKKGVNRRSPAK--
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------KEKNGETATDV----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------SPHRPP-----------
----------------ATKLVSPNSKET---------GHSMDSPGETQLSP-AGLFQ------RPLS-------------
SADVLHVMEVSMTGD---------------QEPEKVQVQLPN--HEPPPQDCTSDEEGADELSTSEEF---------GLE
VENWAKALAHL---WQNRPTN-------------------------LKKEKEYNQRMGCKPPYCSICALFHTYQQVHF--
--CT--VSMEYKRANAPVMGA-GGHMRTKPLIPEMCFITTTEEDSE-QQEESVAPYLEEDGSSLLISCSQCCVRVHTSCY
GVDPT---------TVTKEWKCARCK----ANAMTEDCCLCWLRGGALQR-TSNH-------------------------
-----------------------KWVHVLCAVA----------VLEARFVSISDRSPVDLSGIPLQRFK-----------
---------LKCYYCKKR-MK-KASGCCVQCSHGR-CPTAYHPTCAQAGGVLMQPGEWPFVVHVTCCRHK-----GPAQI
ERNKAAMH-ELSVGQKVICKHKNGRYYQCDVVQLSK--------------ETFYEVNFDDGS----------------FS
DNLFPEDIVS-RDCAQLGPPPSGEVVQVRWTDGLVYGAKFVAA--------HITQMYLVEFEDG-SQLTAKRDDVYTLDE
ELPKRVKSRLS--KASDMRFDGIFEEKEIIRES-KRQRVINSRYRGDYIEPVIYRAIME---------------------
--------------------------------------------------------------------------------
-------------------------------------
>Homo_sapiens_KDM4B
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
MGSEDHGAQNPS------------------------------------------------------CKIMTFRPTMEEFK
DFNKYVAYIESQGAHRAG--------------------------------------------------------------
---------LAKII------------------------------------------------------------------
-------------------PPKEWKPRQ-------------------------------------TYDD-----------
------------------------------------------------------------IDDVVIPAPIQQVVTGQS--
-----------GLFTQYNIQKKAMTVGEYRRLANSE---KYCTPRHQD-FDDLERKYWKNLT---FVSPIYG-ADISGSL
Y-----------------DDDVAQWNIGSLRTILDMVERECGTIIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFG
EPKSWY---AIPPEHGKRLERLAIGFFPGS---SQGCDAFLRHKMTLISPIILKK-YGIPFSRITQEAGE-FMITFPYGY
HAGFN-HGFNCAESTNFATLRWIDYGKVAT--QCTCRKDMVKISMDVFVRILQPERYELWKQGKDLTVLDHTRPTALTSP
ELSSWSA-----------------------------------------SRASLKAKLLRRQISLKENRHWRKTEEERKPS
LERK---------------KEQTKRPGLSSHRKRSQPKKPKPEDPKFPGEG--------------------TAGAALLEE
AGGSVKEEAGPEVDPEEEEEEPQ---------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------PLP-HGREAEGAE-------------------------------
----------------------------------------------------------------------------EDGR
GKLRPTKAKSERKKKSFGLLPP---------------------------------QLPPPPAHFPSEEALWLPSPLEPPV
LGPG----PAAMEESPLPAPLNVVPPEVPS--------------------------------------------------
---EELEAKPRPIIPMLYV------------------------------------------------VPRPGKAAFN---
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------QEHVSCQQAFEHFA-------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------QKGPTWKEPVSPM-----------ELTGPEDGAASSGAGRMETKARAG----------------
-EGQAPSTFSKLKM-------------EIKKSRRHPLGRPP-TRSPLSVVKQEASSDEEASPFSGEED---------VSD
PDALRPLLSLQ---WKNRAAS-------------------------FQAERKFNAAAARTEPYCAICTLFYPYCQALQ--
-TEKEAPIASLGEGCPATLPS-KSRQKTRPLIPEMCFTSGGEN----TEPLPANSYIGDDGTSPLIACGKCCLQVHASCY
GIRPE---------LVNEGWTCSRCA----AHAWTAECCLCNLRGGALQMTTDRR-------------------------
------------------------WIHVICAIA----------VPEARFLNVIERHPVDISAIPEQRWK-----------
---------LKCVYCRKR--MKKVSGACIQCSYEH-CSTSFHVTCAHAAGVLMEPDDWPYVVSITCLKHK--------SG
GHAVQLLR-AVSLGQVVITKNRNGLYYRCRVIGAAS--------------QTCYEVNFDDGS----------------YS
DNLYPESITS-RDCVQLGPPSEGELVELRWTDGNLYKAKFISS--------VTSHIYQVEFEDG-SQLTVKRGDIFTLEE
ELPKRVRSRL--SLSTGAPQEPAFSGEEAKAAKRPRVGTP--LATEDSGRSQDYVAFVESLLQVQGRPGAPF--------
--------------------------------------------------------------------------------
-------------------------------------
>Pan_troglodytes_KDM4B
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
MGSEDHGAQNPS------------------------------------------------------CKIMTFRPTMEEFK
DFNKYVAYIESQGAHRAG--------------------------------------------------------------
---------LAKII------------------------------------------------------------------
-------------------PPKEWKPRQ-------------------------------------TYDD-----------
------------------------------------------------------------IDDVVIPAPIQQVVTGQS--
-----------GLFTQYNIQKKAMTVGEYRRLANSE---KYCTPRHQD-FDDLERKYWKNLT---FVSPIYG-ADISGSL
Y-----------------DDDVAQWNIGSLRTILDMVERECGTIIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFG
EPKSWY---AIPPEHGKRLERLAIGFFPGS---SQGCDAFLRHKMTLISPIILKK-YGIPFSRITQEAGE-FMITFPYGY
HAGFN-HGFNCAESTNFATLRWIDYGKVAT--QCTCRKDMVKISMDVFVRILQPERYELWKQGKDLTVLDHTRPTALTSP
ELSSWSA-----------------------------------------SRASLKAKLLRRQISLKENRHWRKTEEERKPS
LERK---------------KEQTKRPGLSSHRKRSQPKKPKPEDPKFPGEG--------------------TAGAALLEE
AGGSVKEEAGPEVDPEEEEEEPQ---------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------PLP-HGREAEGAE-------------------------------
----------------------------------------------------------------------------EDGR
GKLRPTKAKSERKKKSFGLLPP---------------------------------QLPPPPAHFPSEEALWLPSPLEPPV
LGPG----PAATEESPLPAPLNVVPPEVPS--------------------------------------------------
---EELEAKPRPIIPMLYV------------------------------------------------VPRPGKAAFN---
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------QEHVSCQQAFEHFA-------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------QKGPTWKEPVSPM-----------ELTGPEDGAASSGAGRMETKARAG----------------
-EGQAPSTFSKLKM-------------EIKKSRRHPLGRPP-TRSPLSVVKQEASSDEEASPFSGEED---------VSD
PDALRPLLSLQ---WKNRAAS-------------------------FQAERKFNAAAARTEPYCAICTLFYPYCQALQ--
-TEKEAPTASLGEGCSATLPS-KSRQKTRPLIPEMCFTSGGEN----TEPLPANSYIGDDGTSPLIACGKCCLQVHASCY
GIRPE---------LVNEGWTCSRCT----AHAWTAECCLCNLRGGALQMTTDRR-------------------------
------------------------WIHVICAIA----------VPEARFLNVIERHPVDISAIPEQRWK-----------
---------LKCVYCRKR--MKKVSGACIQCSYEH-CSTSFHVTCAHAAGVLMEPDDWPYVVSITCLKHK--------SG
GHAVQLLR-AVSLGQVVITKNRNGLYYRCRVIGAAS--------------QTCYEVNFDDGS----------------YS
DNLYPESITS-RDCVRLGPPSEGELVELRWTDGNLYKAKFISS--------VTSHIYQVEFEDG-SQLTVKRGDIFTLEE
ELPKRVRSRL--SLSTGAPQEPAFSGEEAKAAKRPRVGTP--LATEDSGRSQDYVAFVESLLQAQGRPGAPF--------
--------------------------------------------------------------------------------
-------------------------------------\r