>Homo_sapiens_PKN1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------MAEANNPSEQELESEPRSWSLLEQLGLAG-ADLAAPGVQQQLELERERLRRE-----------------
--------------------------IRKELKLKEGAENLRRATTDLGRSLGPVELLLRGSS------------------
------------------------------------RRLDLLHQQLQELHAHVVLPDPA---------------ATHDGP
QSPG------------------AGGPTCSATNLSRVAGLEKQLAIELKVKQGAEN---------------------MIQT
YSNGS------------TKDRKLLLTAQQMLQDSKTKIDIIRMQLRRAL---QAGQL-------ENQAAPDDTQG-----
-------SPDLGAVELRIEELRHHFRVEHAVAEGAKNVLRLLSAAKAPDR------------------------------
-----------------KAVSEAQEKLTESNQKLGLLREALERRLGELP------ADHPKGRLLREELAAASS-------
--AAFSTRLAGPFPATHYSTLC-----KPAPLTG-TLEVRVVGCRDLPE-------TIP-WNPTPSMGGPGTPDSRPP--
FLSRPARGLYSR---SGSLSGRSSLKAEAENT-----------SEVSTVLKLDNTVVGQTSW-KPCGPNAWDQSFTLE--
LERARELELAVFWRD--QRGLCALKFLKLEDFLDN-ERHEVQLDMEPQGCLVAEVTFRNPVIERI-PRLRRQKKIFS-KQ
QGKAFQRARQMNIDVATWVRLLRRLIPNATG------TGTFSPGASP---------------GSEARTT-----------
------------------GDISVEKLNLGTDSDSSP-----------------QKSSRDPPS------------------
-------------------------------SPSSLS-------------------------------------------
----------------------------------------------------------------------------SPIQ
ES-TAPELPS----------------------------------------------------------------------
--------------------ETQETPGPALCS------------------------------------------------
----------------------------------------------------PLRKSPLTLEDFKFLAVLGRGHFGKVLL
SEFRPSGELFAIKALKKGDIVARDEVE---SLMCEKRILAAVT-SAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDL--ML
HIHSDVFSEPRAI-FYSACVVLGLQFLHEHKIVY---RDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEF
LAPEVLT-DTSYTRAVDWWGLGVLLYEMLVGESP-FP--GDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRR--LLRRNPE
RRLGSSERDAEDVKKQPFFR--TLGWEALLARRLPPPFVPTLSGRTDVSNFDEEFTGEAPTLSPPRD-------ARPLTA
AEQAAFLDFDFVAGGC-----------
>Pan_troglodytes_PKN1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------MASDAVQSEPRSWSLLEQLGLAG-ADLAAPGVQQQLELERERLRRE-----------------
--------------------------IRKELKLKEGAENLRRATTDLGRSLGPVELLLRGSS------------------
------------------------------------RRLDLLHQQLQELHAHVVLPDPA---------------AAHDGP
QSPG------------------AGGPTCSATNLSRVAGLEKQLAIELKVKQGAEN---------------------MIQT
YSNGS------------TKDRKLLLTAQQMLQDSKTKIDIIRMQLRRAL---QAGQL-------ENQAAPDDTQG-----
-------SPDLGAVELRIEELRHHFRVEHAVAEGAKNVLRLLSAAKAPDR------------------------------
-----------------KAVTEAQEKLTESNQKLGLLREALERRLGELP------ADHPKGRLLREELAAASS-------
--AAFSTRLAGPFPATHYSTLC-----KPAPLTG-TLEVRVVGCRDLPE-------TIP-WNPTPSMGGPGTPDSRPP--
FLSRPARGLYSR---SGSLSGRSSLKAEAENT-----------SEVSTVLKLDNTVVGQTSW-KPCGPNAWDQSFTLE--
LERARELELAVFWRD--QRGLCALKFLKLEDFLDN-ERHEVQLDMEPQGCLVAEVTFRNPVIERI-PRLRRQKKIFS-KQ
QGKAFQRARQMNIDVATWVRLLRRLIPNATG------TGTFSPGASP---------------GSEARTT-----------
------------------GDISVEKLNLGTDSDSSP-----------------QKSSRDPPS------------------
-------------------------------SPSSLS-------------------------------------------
----------------------------------------------------------------------------SPLQ
ES-TAPELPS----------------------------------------------------------------------
--------------------ETRETPGPALCS------------------------------------------------
----------------------------------------------------RLRKS-LTLEDFKFLAVLGRGHFGKVLL
SEFRPSGELFAIKALKKGDIVARDEVE---SLMCEKRILAAVT-SAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDL--ML
HIHSDVFSEPRAI-FYSACVVLGLQFLHEHKIVY---RDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEF
LAPEVLT-DTSYTRAVDWWGLGVLLYEMLVGESP-FP--GDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRR--LLRRNPE
RRLGSSERDAEDVKKQPFFR--TLGWEALLARRLPPPFVPTVSGRTDVSNFDEEFTGEAPTLSPPRD-------ARPLTA
AEQAAFLDFDFVAGGC-----------
>Pongo_abelii_PKN1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------MASDAVQSEPHSWSLLEQLGLAG-ADLAAPGVQQQLELERERLRRE-----------------
--------------------------IRKELKLKEGAENLRRATTDLGRSLGPVELLLRGSS------------------
------------------------------------RRLDLLHQQLQELHAHVVLPDPA---------------ATHDGP
QSPG------------------AGGPTCSATNLSRVAGLEKQLAIELKVKQGAEN---------------------MIQT
YSNGS------------TKDRKLLLTAQQMLQDSKTKIDIIRMQLRRAL---QAGQL-------ENQAAPDETQG-----
-------SPDLGAVELRIEELRHHFRVEHAVAEGAKNVLRLLSAAKAPDR------------------------------
-----------------KAVSEAQEKLTESNQKLGLLREALERRLGELP------ADHPKGRLLREELAAASS-------
--AAFSARLAGPFPATHYSTLC-----KPAPLTG-TLEVRVVGCRDLPE-------TIP-WNPTPPVGGPGTPDSRPP--
FLSRPARGLYSR---SGSLSGRSSLKAEAENT-----------SEVSTVLKLDNTVVGQTSW-KPCGPNAWDQSFTLE--
LERARELELAVFWRD--QRGLCALKFLKLEDFLDN-ERHEVQLDMEPQGCLVAEVTFRNPVIERI-PRLQRQKKIFS-KQ
QGKAFQRARQMNIDVATWVRLLRRLIPNATA------TGTFSPGASP---------------GSEARTT-----------
------------------GDISVEKLNLGTDSDSSP-----------------QKSSRDPPS------------------
-------------------------------SPSSLS-------------------------------------------
----------------------------------------------------------------------------SPIQ
ESSTTPELPS----------------------------------------------------------------------
--------------------ETQETPGPALCS------------------------------------------------
----------------------------------------------------PLRKSPLTLEDFKFLAVLGRGHFGKVLL
SEFRPSGELFAIKALKKGDIVARDEVE---SLMCEKRILAAVT-SAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDL--ML
HIHSDVFSEPRAV-FYSACVVLGLQFLHEHKIVY---RDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEF
LAPEVLT-DTSYTRAVDWWGLGVLLYEMLVGESP-FP--GDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRR--LLRRNPE
RRLGSSERDAEDVKKQPFFR--TLGWEALLARRLPPPFVPTLSGRTDVSNFDEEFTGEAPTLSPPRD-------ARPLTA
GEQAAFLDFDFVAGGC-----------
>Macaca_mulatta_PKN1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------MAEASTPSEQELESEPRSWSLLEQLGLAG-ADLAAPGVQQQLELERERLRRE-----------------
--------------------------IRKELKLKEGAENLRRATTDLGRSLGPVELLLRGSS------------------
------------------------------------RRLDLLHQQLQELHAHVVLPDPA---------------ATHDGP
QSPG------------------AGGPTCSATNLSRVAGLEKQLAIELKVKQGAEN---------------------MIQT
YSNGS------------TKDRKLLLTAQQMLQDSKTKIDIIRMQLRRAL---QAGQL-------ENQAAPDETQG-----
-------DPDLGAVELRIEELRHHFRVEHAVAEGAKNVLRLLSAAKAPDR------------------------------
-----------------KAVSEAQEKLTESNQKLGLLREALERRLGELP------ADHPKGRLLREELAAASS-------
--AAFSARLAGPFPATHYSTLC-----KPAPLTG-TLEVRVVGCRDLPE-------TIP-WNPTPSGGGPGTPDSRPP--
FLSRPARGLYSR---SGSLSGRSSLKADAENT-----------MQCSLYLKIQ---LGRARWLKPVIPALWEA----E--
TGGSRGQEIETILAN--TRGLCALKFLKLEDFLDN-ERHEVQLDMEPQGCLVAEVTFRNPVIERI-PRLRRQKK-FS-KQ
QGKAFQRARQMNIDVATWVRLLRRLIPNATG------TGTFSPGASP---------------GSEARTT-----------
------------------GDISVEKLNLGTDSDGSP-----------------QKSSRDPPS------------------
-------------------------------RLSSLS-------------------------------------------
----------------------------------------------------------------------------SPIQ
ESSITPKLPS----------------------------------------------------------------------
--------------------ETQETPGPALCS------------------------------------------------
----------------------------------------------------PLRKSPLTLEDFKFLAVLGRGHFGKVLL
SEFRPSGELFAIKALKKGDIVARDEVE---SLMCEKRILAAVT-NAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDL--ML
HIHSDVFSEPRAV-FYSACVVLGLQFLHEHKIVY---RDLKLDNLLLDTEGYVKITDFGLCKEGMGYGDRTSTFCGTPEF
LAPEVLT-DTSYTRAVDWWGLGVLLYEMLVGESP-FP--GDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRR--LLRRNPE
RRLGSSERDAEDVKKQPFFR--TLGWEALLARRLPPPFVPTLSGRTDVSNFDEEFTGEAPTLSPPRD-------ARPLTA
AEQAAFLDFDFVAGGC-----------
>Mus_musculus_PKN1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------MAADPPLDSELESEPRSWSLLEQLGLAG-ADLAAPGVQQQLELERERLKRE-----------------
--------------------------IRKELKLKEGAENLRRATTDLGRSLAPVELLLRGSA------------------
------------------------------------RRLDLLHQQLQELHAHVVLPDPA---------------AGSDAT
QSLA------------------EGSPICSSTNLSRVAGLEKQLAIELKVKQGAEN---------------------MIQT
YSNGS------------SKDRKLLLTAQQMLQDSKTKIDIIRMQLRRALQALQAGEL-------ESQAAPDEAQG-----
-------DPELGAVELRIEELRHHFRVEHAVAEGAKNVLRLLSGAKAPDR------------------------------
-----------------KAVSEAQEKLTESNQKLGLLRESLERRLGELP------ADHPKGRLLREELTAASS-------
--SAFSAILPGPFPATHYSTLS-----KPAPLTG-TLEVRVVGCKNLPE-------TIP-WSPPPSVGASGTPESRTP--
FLSRPARGLYSR---SGSLSGRSSLRGEAENA-----------TEVSTVLKLDNTVVGQTAW-KPCGPNAWDQSFTLE--
LERARELELAVFWRD--QRGLCALKFLKLEDFLDN-ERHEVQLDMEPQGCLVAEVTFRNPIIERI-PRLQRQKKIFS-KQ
QGKAFQRARQMNIDVATWVRLLRRLIPSAVA------TGTFSPNASP---------------GAEIRHT-----------
------------------GDISMEKLNLGADSDSSS-----------------QKSPPGLPS------------------
-------------------------------TSCSLS-------------------------------------------
----------------------------------------------------------------------------SPTH
ESTTSPELPS----------------------------------------------------------------------
--------------------ETQETPGPGLCS------------------------------------------------
----------------------------------------------------PLRKSPLTLEDFKFLAVLGRGHFGKVLL
SEFRSSGELFAIKALKKGDIVARDEVE---SLMCEKRILAAVT-RAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDL--ML
HIHSDVFSEPRAV-FYSACVVLGLQFLHEHKIVY---RDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEF
LAPEVLT-DTSYTRAVDWWGLGVLLYEMLVGESP-FP--GDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRR--LLRRNPE
RRLGSTERDAEDVKKQPFFR--SLGWDVLLARRLPPPFVPTLSGRTDVSNFDEEFTGEAPTLSPPRD-------ARPLTA
AEQAAFRDFDFVAGGY-----------
>Rattus_norvegicus_PKN1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------MAGD-----AVQSEPRSWSLLEQLGLAG-ADLAAPGVQQQLELERERLKRE-----------------
--------------------------IRKELKLKEGAENLRRATTDLGRSLAPVELLLRGSA------------------
------------------------------------RRLDLLHQQLQELHAHVVLPDPT---------------AGSDAP
QSLA------------------EGSPVCSSTNLSRVAGLEKQLAIELKVKQGAEN---------------------MIQT
YSNGS------------TKDRKLLLTAQQMLQDSKTKIDIIRMQLRRALQALQAGQL-------ESQAAPDEAHG-----
-------DPDLGAVELRIEELRHHFRVEHAVAEGAKNVLRLLSAAKAPDR------------------------------
-----------------KAVSEAQEKLTESNQKLGLLRESLERRLGELP------ADHPKGRLLREELTAASS-------
--AAFSAILPGPFPATHYSTLS-----KPAPLTG-TLEVRVVGCKNLPE-------TIP-WSPPPSVGASGTPDSRTP--
FLSRPARGLYNR---SGSLSGRSSLKGEAENS-----------TEVSTVLKLDNTVVGQTAW-KPCGPNAWDQSFTLE--
LERARELELAVFWRD--QRGLCALKFLKLEDFLDN-ERHEVQLDMEPQGCLVAEVTFRNPIIERI-PRLQRQKKIFS-KQ
QGQTFQRARQMNIDVATWVRLLRRLIPNAVA------TGSFSPNASP---------------GSEIRST-----------
------------------GDISMEKLNLGADSDSSS-----------------QKSPAGLPS------------------
-------------------------------TSCSLS-------------------------------------------
----------------------------------------------------------------------------SPTH
ESTTSPELPS----------------------------------------------------------------------
--------------------ETQETPGPGLCS------------------------------------------------
----------------------------------------------------PLRKSPLTLEDFKFLAVLGRGHFGKVLL
SEFHSSGELFAIKALKKGDIVARDEVE---SLMCEKRILATVT-RAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDL--ML
HIHSDVFSEPRAV-FYSACVVLGLQFLHEHKIVY---RDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEF
LAPEVLT-DTSYTRAVDWWGLGVLLYEMLVGESP-FP--GDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRR--LLRRNPE
RRLGSTERDAEDVKKQPFFR--TLDWDALLARRLPPPFVPTLSGRTDVSNFDEEFTGEAPTLSPPRD-------ARPLTA
AEQAAFRDFDFVAGGY-----------
>Canis_familiaris_PKN1
--------------------------------------------------------MLGFEPRSAQSPSAGNGGSFPGDS
SLQRRGRGGGGESLLFSEGSREARRPLPRPALTWLSLSFGFPRAQLGHPGAERGAAPGTRGSSRQGGRGRRPAEPRRRDP
QPRGPPGAAPPPPRPLPGRRPRRSRDPARRPLGPEGAARGRGGLARRGRSGRSRPERAARRRGLRRARPFPAPRGAHARS
SRRPSLRAGTPGGRREDMASDAVQSEPRSWSLLEQLGLAG-ADLAAPGVQQQLELERERLRRE-----------------
--------------------------IRKELKLKEGAENLRRATTDLGRSLGPVELLLRGSS------------------
------------------------------------RRLDLLHQQLQELHAHVVLPDPA-A-------------AARDAP
LSPG------------------ASGQACSATNLSRVAGLEKQLAIELKVKQGAEN---------------------MIQT
YSNGS------------TKDRKLLLTAQQMLQDSKTKIDIIRMQLRRAL---QAGQL-------ESQAAPDEAQG-----
-------SPDLGAVELRIEELRHHFRVEHAVAEGAKNVLRLLSAAKAPDR------------------------------
-----------------KAVSEAQEKLTESNQKLGLLREALERRLGELP------ADHPKGRLLREELAAASS-------
--AAFSARLAGPFPPTPYSTLC-----KPAPLTG-TLEVRVVGCKDLPE-------TIP-WSSSPVAGVPGTPDSRTT--
FLSRPARGLYSR---SGSLSGRSSLKVEAENT-----------SEVSTVLKLDNTVVGQTSW-KPCGPSAWDQSFTLE--
LERARELELAVFWRD--QRGLCALKFLKLEDFLDN-ERHEVQLDMEPQGCLVAEVTFRNPVIERI-PRLRRQKKIFS-KQ
QGKAFQRARQMNIDVATWVRLLRRLIPNATA------TSTFSPGASP---------------GPEVRST-----------
------------------GDISVEKLNLGTALDSLP-----------------QKSPLGPPS------------------
-------------------------------SPSSLS-------------------------------------------
----------------------------------------------------------------------------SPIQ
ETTTTPEPPS----------------------------------------------------------------------
--------------------ETQETPGPALSS------------------------------------------------
----------------------------------------------------PLKKSPLTLEDFKFLAVLGRGHFGKVLL
SEFRPSGELFAIKALKKGDIVARDEVE---SLMCEKRILAAVT-RAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDL--ML
HIHSDVFSEPRAV-FYSACVVLGLQFLHEHKIVY---RDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTSTFCGTPEF
LAPEVLT-DTSYTRAVDWWGLGVLLYEMLVGESP-FP--GDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRR--LLRRNPE
RRLGSSERDAEDVKKQPFYR--TLVWDSLLARRLPPPFVPTLSGRTDVSNFDEEFTGEAPTLSPPRD-------ARPLTA
AEQAAFRDFDFVAGGC-----------
>Felis_catus_PKN1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------MEVRAIVTLSSPPPP-------------HLLDAP
QSPG------------------AGSQACSATNLSRVAGLEKQLAIELKVKQGAEN---------------------MIQT
YSNGS------------TKDRKLLLTAQQMLQDSKTKIDIIRMQLRR------AGQL-------ESQAAPDDAQG-----
-------SADLGSVELRIEELRHHFRVEHAVAEGAKNVLRLLSAAKAPDR------------------------------
-----------------KAVCEAQEKLTESNQKLGLLREALERRLGELP------ADHPKGRLLREELAVASS-------
--AAFSARLAGPFPPTHYNTLC-----KPAPLTG-TLEVRVVGCRDLPE-------TVP-WSSSPSVGVPGTPDSRTT--
FLSRPARGLYSR---SGSLSGRGSLKVEAENT-----------SEVSTVLKLDNTVVGQTSW-KPCGPNAWDQSFTLE--
LERARELELAVFWRD--QRGLCALKFLKLEDFLDN-ERHEVQLDMEPQGCLVAEVTFRNPVIERI-PRLRRQKKIFS-KQ
QGKTFQRARQMNIDVATWVRLLRRLIPNATA------TGTFSPGASP---------------GPEARST-----------
------------------GDVSMEKLNLGADLDSLP-----------------QKSPLGPPS------------------
-------------------------------SPSSLS-------------------------------------------
----------------------------------------------------------------------------SPIQ
ETTTTPELPS----------------------------------------------------------------------
--------------------ETQETPGPALCS------------------------------------------------
----------------------------------------------------PLRKSPLTLEDFKFLAVLGRGHFGKVLL
SEFRPSGELFAIKALKKGDIVARDEVE---SLMCEKRILAAVT-RAAHPFLVNLFGCFQTPEHVCFVMEYSAGGDL--ML
HIHSDVFSEPRAV-FYSACVVLGLQFLHEHKIVY---RDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEF
LAPEVLT-DTSYTRAVDWWGLGVLLYEMLVGESP-FP--GDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRR--LLRRNPE
RRLGSSERDAEDVKKQPFFR--TLGWDTLLARRLPPPFVPTLSGRTDVSNFDEEFTGEAPTLSPPRD-------ARPLTA
TEQAAFRDFDFVAGGC-----------
>Bos_taurus_PKN1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------QSEPRSWSLLEQLGLAG-ADLAAPGVQQQLELERERLRRE-----------------
--------------------------IRKELKLKEGAENLRRATTDLGRNLGPVELVLRGSS------------------
------------------------------------RRLALLHQQLQELHAHVVLPDPA-V-------------GVHDAP
QSPG------------------TGDSACSATNLSRVAGLEKQLAIELKVKQGAEN---------------------MIQT
YSNGS------------TKDRKLLLTAQQMLQDSKTKIDIIRMQLHRAL---QACQL-------ESQAAPDEAQG-----
-------SPDLGAVELRIEELRHHFRVEHAVAEGAKNVLRLLSAAKAPDR------------------------------
-----------------KAVSEAQEKLTESNQKLGLLREALERRLGELP------ADHPKGRLLREELAAASS-------
--AAFSARLAGPFPATHYSTLS-----KPAPLTG-TLEVRVVGCRDLPE-------TIP-WNPSPSVGGPGTPDSRTP--
FLSRPARGLYSR---TGSLSGRSSLKAEAENT-----------NEVSTVLKLDNTVVGQTSW-KPCGPNAWDQSFTLE--
LERARELELAVFWRD--QRGLCALKFLKLEDFLDN-ERHEVQLDMEPQGCLVAEVTFRNPVIERI-PRLRRQKKIFS-KQ
QGKAFQRARQMNIDVATWVRLLRRLIPNATA------TGTFSPGASP---------------GPEARST-----------
------------------GDISVEKLNLGTETDSSP-----------------QKSPLGPPS------------------
-------------------------------SPSSLS-------------------------------------------
----------------------------------------------------------------------------SPIQ
ATTTTPELPS----------------------------------------------------------------------
--------------------ETQETPGPTLCS------------------------------------------------
----------------------------------------------------PLRKSPLTLEDFKFLAVLGRGHFGKVLL
SEFRPSGELFAIKALKKGDIVARDEVE---SLMCEKRILAAVT-NAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDL--ML
HIHSDVFSEPRAV-FYSACVVLGLQFLHEHKIVY---RDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEF
LAPEVLT-DTSYTRAVDWWGLGVLLYEMLVGESP-FP--GDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRR--LLRRNPE
RRLGSSERDAEDVKKQPFFR--TLGWDALLARRLPPPFVPTLAGRTDVSNFDEEFTGEAPTLSPPRD-------ARPLTA
TEQAAFRDFDFVAGSC-----------
>Loxodonta_africana_PKN1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------LQSESRNWSLLEQLGLAG-ADLAAPGVQQQLELERERLRRE-----------------
--------------------------IRKELKLKEGAENLRRATTDLGRNLGPVELLLRGSS------------------
------------------------------------RRLDLLHQQLQELHAHVVLPDPA---------------TAARG-
-LQG------------------LPLPRCARTALAARPAREVQYHLHWPQRD---R---------------------LCHS
NSESP------------NTDRKLLLTAQQMLQDSKTKIDIIRMQLRRAL---QAGQL-------ESHVAPDEAQG-----
-------KAQMGAHEKNMEGIRKVTKPKRASRENAP-KTRLSHCGTGPGP------------------------------
-----------------ASPPQAQEKLTESNQKLGLLREALERRLGELP------ADHPKGRLLREELAAATS-------
--SAFSVLLAGPFPATHYSTLC-----KPAPLTG-TLEVRVLGCRDLPE-------TIP-WSPSPSGGGPGASDSRTP--
FLSRPARGLYSR---SGSLSGRSSLKAEAENT-----------SEVSTVLKLDNTVVGQTSW-KPCGPNAWDQSFTLE--
LERARELELAVFWRD--QRGLCALKFLKLEDFLDN-ERHEVQLEMEPQGCLLAEVTFRNPVIERI-PRLRRQKKIFS-KQ
QGKTFQRARQMNIDVATWVRLLRRFIPNGTT------TGTFSPGASP---------------GPEARSM-----------
------------------GDISVEKLNLGTNSDSSP-----------------QKSPLEPPS------------------
-------------------------------SPSSLS-------------------------------------------
----------------------------------------------------------------------------SQIQ
EPPP-TSEPPP---------------------------------------------------------------------
--------------------ETQETPGPALCS------------------------------------------------
----------------------------------------------------PLRKSPLTLKDFKFLAVLGRGHFGKVLL
SEFQPSGELFAIKALKKGDIVARDEVE---SLMCEKRILAAVT-SVGHPFLVNLFGCFQTPEHVCFVMEYSAGGDL--ML
HIHSDVFSEPRAV-FYSACVVLGLQFLHEHKIVY---RDLKLDNLLLDTKG-SKIADFGLCKEGMGYGDRTSTFCGTPEF
LAPEVLT-DTSYTRAVDWWGLGVLLYEMLVGEVSTLP--SLPHASLRPDMEPSCVQGWGLKSASTMCVACR-GQRRRPAS
PSLLASGPQPSMLTPPPAQQ--TLGWDSLLARRLPPPFVPKLSGRTDVSNFDEEFTGEAPTLSPPRD-------ARPLTA
TEQAAFQDFDFVAGGC-----------
>Monodelphis_domestica_PKN1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------MASDALQSEPGTWSVLEQLGLAG-ADLAAPGVQQRLELEVERLRRE-----------------
--------------------------IRKELKLKEGAENLRRATTDLGRSLGPVELLLRGST------------------
------------------------------------RRLDLLHSQLQELHGLVVLHEPRQA-------------QPQLGQ
AQDG------------------PQSPNCPATSLSLVAGLEKQLTIELKVKQGAEN---------------------MIHT
YSNGN------------TKERKLLLTAQQMLQDSKTKIDIIRMQIRKAL---QAGQL-------ENQG-PEESHG-----
-------GPDLGAVELRIEELRHHFRVEHAVAEGAKNVLRLLSAAKAPDR------------------------------
-----------------KAVSEAQAKLTESSQKLALLRAALELRLGELP------AEHPKGRLLLEELAMASS-------
--STFSTRIG-PFPATHYSTLC-----KPSPLTG-TLSVRVLGCSGLPE-------TVP-WSSPPTSGSSGTSESRP---
FLGRPARGLYSR---SGSLSGRGSIKTEEP-T-----------NEVSAVLKVDNTVVGQTPW-KPCGPNAWDQSFTLE--
LERARELELSIFWRD--HRGLCALKFLKLEDFLDN-QRHQVQLELEPQGCLLAEVIFHNPVIERI-PRLQRQKKVFS-KQ
QGKAFLRARQMNIDIATWVRLLRRLLPSPNS------TGTFSPGAT----------------TAEGRTS-----------
------------------GDIPIEKLNL--DSDSST-----------------QKSPLDLLS------------------
-------------------------------SPSSLSSPSS---------------------------------------
---------------------------------------------------------------------------LSPRS
QDTPQPSESTP---------------------------------------------------------------------
--------------------EDRETPGPTPSS------------------------------------------------
----------------------------------------------------PLRTSPLSLNDFKFLAVLGRGHFGKVLL
SEYLPSGELFAVKALKKGDIVARDEVE---SLMCEKRILGRGD-GRLPSLLGQPVRLLPDPRARVLRHGVRGGRGP--DA
AHPSDVFTEPRAV-FYSACVVLGLQFLHDHKIVY---RDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTSTFCGTPEF
LAPEVLT-DTSYTRAVDWWGLGVLLYEMLVGESP-FP--GDDEEEVFDSIVNDEVRYPRFLSTEAIGIMRR--LLRRNPE
RRLGSGERDAEDVKKQPFFR--TLGWEALLARQLPPPFIPVIKGRTDISNFDEEFTGEAPALTPPRE-------ARPLSA
AEQEAFRDFDYVSKGC-----------
>Anolis_carolinensis_PKN1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------MANESLQ---------SDPGNWSVLEHLGLDQSSDFSDISVQQKLDEEKDKIKRE-----------------
--------------------------IRKELKIKEGAENLRKATTDR-KNLSNVENLLKSSN------------------
------------------------------------RKLETLHHQLQDLNAHIVVKDPEEL---------------AEAP
QSPG------------------SLSR--STATQNRIAGLEKQLNIELKVKQGAEN---------------------MIQM
YANGT------------AKDRKLLQTAQQMLQDSKTKINIIRMQIRKAM---------------QADEVQLNMEDGQ---
------GNADLSAIELRIEELRHHFRVEHAVSEGAKNVLRLLGASKVQDR------------------------------
-----------------HAISEAQMKLNESSQKLDLLRHSLEQRLSELP------QDHPKGCIIKEELILDSS-------
--PTFSVRNNTSYQHNQYNTLS-----KPSPLTG-TLEVQLLGCSGLLE-------FVPGRTRGSTVSLPCNSSFMSR--
S----GRGLYSR---SGSVSGRTTIKCEDIS------------NEVSAVLKLDNGVVGQTAW-KPIGLQAWNQTFTVE--
LERARELEIGVYWRD--YRSLCALKYLKLEDFLDN-QRHEIHLELEPQGTLLAEVTFFNPVIERI-PKLQRQKKIFS-KQ
QGKAFLRARQMNIDIATWVRLLRRIIPTAST------TGTYSPSTQMNPAVGSE--------SRHSLNS-----------
------------------GDVAIEKLNLEGDRV---------------------EQMGQDDS------------------
-------------------------------ELPGKVLLG----------------------------------------
---------------------------------------------------------------------------LQTGE
EIPFQLELGPG---------------------------------------------------------------------
-------------------CEARGSESIFPS-------------------------------------------------
----------------------------------------------------HLRKTPLTMDDFRFVAVLGRGHFGKVLL
SELHRTGNLFAIKALKKGDIIARDEVE---SLMCEKRIFEIVT-HAKHPFLVNLFACFQTPQHVCFVMEYTAGGDL--MM
HIHTDVFTEPRAT-FYAACVVLGLQFLHDHKIVY---RDLKLDNLLLDTEGYVKIADFGLCKEGMGYADRTSTFCGTPEF
LAPEVLT-DTSYTRAVDWWGLGVLIYEMLVGESP-FP--GDDEEEVFDSIVNDEVRYPRFLSTEAIGIMRR--LLRRNPE
RRLGSSERDAEDVKKQPFFR--SIEWEALLARKIKPPFVPVIKGREDISNFDEEFTAEAALLTPPRE-------SRPLTQ
KEQDSFKDFDYVSNAC-----------
>Danio_rerio_PKN1_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------MA
SEEGRNTSLTEQHDDDTITQTETPSDPGGLSGLERLGLDHSSDYSDSSVQQRLDKERERIRRE-----------------
--------------------------IRKELKIKEGAENLRRATTDK-RNAQQVDSQLRCSN------------------
------------------------------------RRLDSLHAELQELDAHIVVKGTDDT--------------HDDAP
QSPG------------------AESR--SSAHKERIAALERQLNIELKVKQGAEN---------------------MIPI
YTNGS---------------------TKQMLQDSKTKIDIIRMQIRKAV---------------QAYEHNDDTQG-----
-------KPDPCGMELRIEELRHHYRVEHAVAEGAKNVLRLLGAS-----------------------------------
---------------------KAQCRLSESSQRLDLLRDSLDRRLAELP------EDHPKASVIKEELVLASS-------
--PAFSSQHSAPYLHNQYSTLS-----KPSPLTG-RLQVTLLGCMGLLE-------VVPGRSRGSQVVLPCYSPGEGR--
SFMRSGKGLYSR---SGSVSGKTPLKTDELS------------SDVSAVLKLDNTVVCQTAW-KMVGEQGWDQTFIIE--
LERSREMEIAVYWRD--YRSLCALKFLKLEDFLDN-QKHKVQLELEPQGLLLAEVTFFNPVIERV-PRLKRQKNVFS-KQ
QGKAFLRARQMNVDIGTFVRLLRNAIPTVNN------TGTYSPNAH-------------------TLQT-----------
------------------GEISVEKLSLDFDSP----------------------MKVDIRR------------------
-------------------------------EVTDISTPE----------------------------------------
---------------------------------------------------------------------------RQPST
EPLSAPDVTT----------------------------------------------------------------------
---------------------PIRTHSLSSK-------------------------------------------------
-----------------------------------------------------QKKTSLSLQDFRLIAVLGRGHFGKVLL
AEYKKSGSMYAIKALKKGDIVARDEVE---SLMCEKRIFEAVN-GAQHPFLVNLFACFQTPEHVCFVMEYTAGGDL--MM
HIHADVFTEPRAV-FYSACVVLGLQFLHDNKIVY---RDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTSTFCGTPEF
LAPEVLT-DTSYTRAVDWWGLGVLIYEMLVGESP-FP--GDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRR--LLRRNPE
RRLGSSEKDAEDVKKQPFFR--NMDWEALLLRKLPPPFIPSIGGKEDVSNFDEEFTTEAPTLTPPRE-------PRVLSR
KDQDSFRDFDYVSDLC-----------
>Takifugu_rubripes_PKN1_b
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------MSSAAEMGQFLFVVLESDPGGLSVLEQLGLDQNSDFSDSGVQQLLDEQREKIRRE-----------------
--------------------------IRKELKIKEGAENLRRATTDK-RNAQQVDSQLRSSN------------------
------------------------------------RRLENLHDQLQELDAHIVVKGGEEN--------------KEECP
LSPG------------------TDRR--TSAHRDRIAALERQLNIELKVKQGVEN---------------------MIPI
YSNGS------------TKDKKMLQTAQQMLQDSKTKIDIIRMQIRKAM---------------QANEQSDDTQG-----
-------NQDVCGVELRIEELRHHYRVEHAVAEGAKNVLRLLSASKVQDK------------------------------
-----------------KALSEAQSRLSEASQRLDLLRDSLEQRLAELP------EDHPKASVIKEELVLASS-------
--PAFSSRHGAPYLHNQYSTLN-----KPSPLTG-TLQVQLVGCVGLLE-------VVPGRSKGITVMLPCYCPGDTR--
SFMRGSKGLYGR---TGSVSGKTASKTDELS------------FEVSAVLKLDNTVVGQTVW-KTVGEQAWDQTFTVE--
LERSRELEIAVYWKD--YRSLCALKYVKLEDFLDN-QKHRVQLELEPQGLLLAEVTFFNPVIERV-PRLQRQKKVFS-KQ
QGKAFLRARQMNVDIGTWVRLLRNAIPTVNN------SGTYSPNAHS-----------------LTLHP-----------
------------------GEVSVEKLSLDADSPIRGDYKRDMETHTPVRQA--QSGGVCVSI------------------
-------------------------------ILGRFKTVNNL--------------------------------------
---------------------------------------------------------------------------EVPQT
DSVCLFPLTSPVR-------------------------------------------------------------------
------------------NECPSLSPSLPQTSPQSA--------------------------------------------
---------------------------------------LSEPHLLAVENPNKQKKGPLSLQDFRMIAVLGRGHFGKVLL
SEYKKTGTMYAIKALKKGDIIARDEVE---SLMCEKRIFEIVN-MSHHPFLVNLLACFQTPEHVCFVMEYTAGGDL--MM
HIHTDVFTEPRAV-FYSACVVLGLQFLHDHKIVY---RDLKLDNLLLDTDGYVKIADFGLCKEGMGFGDRTSTFCGTPEF
LAPEVLT-DTSYTRAVDWWGLGVLIYEMLVGESP-FP--GDDEEEVFDSIVNDEVRYPRFLSNEAIGIIRREQLLRRNPE
RRLGSGEKDAEEVKKQPFFR--TMDWEALLQRKVPPPFLPSITGKEDVSNFDEEFTAEAPTLTPPRE-------PRTLSR
KDQESFRDFDYVSDLC-----------
>Tetraodon_nigroviridis_PKN1_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------EPDDAEK---------SDPGGLSVLEQLGLDQNSDFSDSGVQQLLDEQREKIRRE-----------------
--------------------------IRKELKIKEGAENLRRATTDK-RNAQQVDSQLRSSN------------------
------------------------------------RRLEDLHAQLQELDAHIVVKGGEEN--------------KEECP
LSPG------------------TDSR--TSAHKDRIAALERQLNIELKVKQGVEN---------------------MIPV
YSNGS------------TKDKKMLQTAQQMLQDSKTKIDIIRMQIRKAM---------------QANEQSDDTQASIP--
-DY-NHSNQDVCGVELRIEELRHHYRVEHAVAEGAKNVFRLLSASKVQDK------------------------------
-----------------KALSEAQSRLSEASQRLDLLRDSLEQRLAELP------EDHPKASVIKEELVLASS-------
--PAFSSRHGAPYLHNQYSTLN-----KPSPLTG-TLQVQLVGCVGLLE-------AVPGRSKGTTVMLPCYSPGDTR--
SFMRGSKGLYGR---TGSVSGKTASKTDELS------------SEVSAVLKLDNTVVGQTVW-KTVGDQAWDQTFTVE--
LERSRELEIAVYWKD--YRSLCALKYVKLEDFLDN-QKHRVQLELEPQGLLLAEVTFFNPVIERV-PRLQRQKKVFS-KQ
QGKAFLRARQMNVDIGTWVRLLRNAIPTVNN------SGTYSPNAHS-----------------VTLHP-----------
------------------GEVSVEKLSLDTDSP---------------------SGCVSLSS------------------
-------------------------------HIPRQE-------------------------------------------
---------------------------------------------------------------------------RMPVI
EPFSPPDLTP----------------------------------------------------------------------
-------------------ECPVRTPSLGRS-------------------------------------------------
----------------------------------------------------KQRKGPLSLQDFRMIAVLGRGHFGKVLL
SEYKKTGTMYAIKALKKGDIIARDEVE---SLMCEKRIFEIVN-VSHHPFLVNLFACFQTPEHVCFVMEYTAGGDL--MM
HIHTDVFTEPRAM-FYSACVVLGLQFLHDHKIVY---RDLKLDNLLLDTDGYVKIADFGLCKEGMGFGDRTSTFCGTPEF
LAPEVLT-DTSYTRAVDWWGLGVLIYEMLVGESP-FP--GDDEEEVFDSIVNDEVRYPRFLSNEAIGIIRR--LLRRNPE
RRLGSGEKDAEEVKKQPFFR--TMDWEALLQRKVPPPFLPSITGKEDVSNFDEEFTTEAPTLTPPRE-------PRMLTR
KDQESFRDFDYVSDLC-----------
>Gasterosteus_aculeatus_PKN1_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------FLFLVVQ---------SDPGGLSVLEQLGLDQNSDFSDTGVQQLLDEHRERIRRE-----------------
--------------------------IRRELKIKEGAENLRRATTDK-RNAQQVESQLRSSN------------------
------------------------------------RKLDDLHAQLQELDAHIVHLVPSIG--------------TDECP
QSPG------------------AESR--TSAHKERIAALERQLNIELKVKQGVEN---------------------MIPI
YGLQSPF----------NQDKKMLQTAQQMQQDSKTKIDIIRMQIRKAV---------------QATEHNEDTQAPN---
----TAGNQDLCGMELRIEELRHHYRVEHAVAEGAKNVLRLLGAGKVQDK------------------------------
-----------------KALSEAQSRLSEASQRLDLLRDSLDQRLAELP------EDHPKATVIKEELVLASS-------
--PAFSSRHGAPYLHNQYNTLN-----KPSPLTG-TLQVQVLGCVGLLE-------VVPGRTKGVAVMLPCYSPGDTR--
SFMRGSKGLYGR---SGSVSGKTPSKAEELSL-----------AEVSAVLKLDNGVVGQTAW-KTVGEQAWDQTFTVE--
LERSREMEIAVYWKD--YRSLCALKYLKLEEFLDN-QKHRVQLELEPQGLLMAEVIFFNPVIERV-PRLQRQKKVFS-KQ
QGKAFLRARQMNVDIGTWVRLLRNAIPTANN------SGTYSPNTQG-----------------LMLSA-----------
------------------GEVSVEKLNLDSDSP----------------------MRVFLSS------------------
-------------------------------RVPPQD-------------------------------------------
---------------------------------------------------------------------------RLTVI
EPFSPPDLTP----------------------------------------------------------------------
-------------------ECPVRTQSIGRLR------------------------------------------------
-----------------------------------------------VRLSSKQRKGPLSLQDFRLIAVLGRGHFGKVLL
SEYKKTGTMYAIKALKKGDIVARDEVE---SLMCEKRIFEVVN-MSHHPFLVNLFACFQTPQHVCFVMEYTAGGDL--MM
HIHTDVFTEPRAV-FYAACVVLGLQFLHDHKIVY---RDLKLDNLLLDTDGYVKIADFGLCKEGMGFGDRTSTFCGTPEF
LAPEVLT-DTSYTRAVDWWGLGVLIYEMLVGESP-FP--GDDEEEVFDSIVNDEVRYPRFLSTEAIGIMRR--LLRRNPE
RRLGSGEKDAEEVKKQPFFR--HVDWEALLQKKVPPPFIPSIVGKEDVSNFDEEFTAEAPALTPPRE-------PRVLSR
KDQESFCDFDYVSDLC-----------
>Oryzias_latipes_PKN1_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------MANDSVQ---------SDPGGLSVLELLGLDQSSDFSDSSVQQLLDEQRERIRRE-----------------
--------------------------IRKELKIKEGAENLRRATTDK-RNAQQVESQLRTSN------------------
------------------------------------RRLDHLHAQLQELDAHIVVKGGEEN--------------KDECP
QSPG------------------AESR--TSAHRDRIAALERQLNIELKVKQGVEN---------------------MIPI
YANGS------------TKDKKMLQTAQQMLQDSKTKIDIIRMQIRKAV---------------QATEHSDDTQG-----
-------NQDLCGVELRIEELRHHYRVEHAVAEGAKNVLRLLGASKVQDK------------------------------
-----------------KALSEAQSRLGEASQRLDLLRDSLDRRLAELP------EDHPKANVIKEELVLAAS-------
--PAFSSRHGAPYLHNQYSTLN-----KPSPLTG-TLQVQLLGCVGLLE-------TVPGRSKGSAVTLPCYSPGDSR--
SFMRSSKGLYGR---TGSVSGKTPNKSDELS------------TEVSAVLKLDNGVVGQTAW-RTVGEQAWDQTFTVE--
LERSREMEIAVYWRD--FRSLCALKYLKLEEFLDN-QKHRVQVELEPQGLLLAEVTFFNPVIERV-PRLQRQKKVFS-KQ
QGKAFLRARQMNVDIGTWVRLLRNAIPTANN------SGTYSPTAHS-----------------LSLNS-----------
------------------GEISVEKLSLDSDTPLRGDYKRDTDQQTPVRRKGNLGKRDKIKK------------------
-------------------------------MILNLEARANF--------------------------------------
---------------------------------------------------------------------------RRVFE
DVVGVNGFSSKEKDL-----------------------------------------------------------------
----------------HKYDGAFSSTSISNLT------------------------------------------------
---------------------------------------------QFDDLLSEEKKGPLSLQDFRLIAVLGRGHFGKVLL
SEYKKTGTMYAIKALKKGDIIARDEVD---SLMCEKRIFEIVN-MSHHPFLINLFACFQTSQHVCFVMEYTAGGDL--MM
HIHTDVFTEPRAV-FYAACVVLGLQFLHDHKIVY---RDLKLDNLLLDTDGYVKIADFGLCKEGMGYGDRTSTFCGTPEF
LAPEVLT-DTSYTRAVDWWGLGVLIYEMLVGESP-FP--GDDEEEVFDSIVNDEVRYPRFLSTEAIGIMRR--LLRRNPE
RRLGSGEKDAEEVKKQPFFR--SVDWEALLQRKVPPPFVPSIRGKEDVSNFDEEFTTEPPTLTPPRE-------ARSLTR
KDQDCFRDFDYVSDLC-----------
>Oryzias_latipes_PKN1_b
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------ISLSPLQ---------TDPNGLSVLQQLGLDQNSDFSDCSVQQRLDEHRERIRRE-----------------
--------------------------IRKELKIKEGAENLRRAT-DK-RNVQQVDSQLRSSK------------------
------------------------------------RKLESLHAQLQELDAHIVVKGQEENKVT----------PVSDDS
KSPG------------------SVNR--TSANQHRIAALERQLNIELKVKQGAEN---------------------MIPI
YASGG------------TKDKKLLQTAQQMLQDSKTKIDIIRMQIRKAM---------------QATEQSEDNQS-----
-------KPDLCGVELRVEELWHHYRVEHAMAEGAKNMLRLLGAGKVQDK------------------------------
-----------------KAINEAQCGLSGSSQRLDLLRCALEQRLQELP------EDHPKVCLIKEELVLASS-------
--SAFSSSHSTPYVHNQYSTLS-----KPSPLTG-TLQVRLLGCVGLLE-------VVPGRSKGAPVVLPSYSTSDGR--
PSFKLS-GLYSRS--TSSMSLKIPSKNEELS------------SEVSAVLKLENTVVGQTAW-RTVGEQAWDQSFTLE--
LERSREMEIAVYWRD--YRSLCALKYLKLEDFLDN-QRHQVQLELEPQGLLVAEVTFFNPVIERG-RRLQRQKKVFS-KQ
HGKAFLRARQMNVDIATWVRLLRNAIPSGSNPPSLFTSNTLSQAPGY-----------------VRESN-----------
------------------DHSSFIKLLINTVGG-------------GIRSGVMNDSCLLLQM------------------
-------------------------------LVARLPPFSS---------------------------------------
---------------------------------------------------------------------------LFLLL
PCSSQQDQTPVIEAP-----------------------------------------------------------------
----------------PTAEVPAHKQPARSPS------------------------------------------------
-----------------------------------------------QNSLRRASRGPVSLQDFKLLAVLGRGHFGKVLL
SEYKKTGGLFAIKALKKGDIVARDEVE---SLMCEKRIFETVN-GSHHPFLVNLFACFQTPEHVCFVMEYTAGGDL--MM
HIHADVFAEPRAV-FYSACVVLGLQFLHDHKIVY---RDLKLDNLLLDTEGFVKIADFGLCKEGMGFGDRTSTFCGTPEF
LAPEVLT-DTSYTRAVDWWGLGVLIYEMLVGESP-FP--GDDEEEVFDSIVNDEVRYPRFLSTEAIGIMRR--LLRRNPE
RRLGSGEKDAEDVKKQPFFR--NTDWEGLLHRKVSPPFVPTIVGKEDVSNFDAEFTAEPAALTPPRE-------RRTLSQ
KEQDFFKDFDYVSDLC-----------
>Ciona_savignyi_PKN1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------PPPP----PDPAIP------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------PEEQQKDP------RIGGLEKQLRIEMMVKQGAEN---------------------MMKS
YTSGH------------GKDRKLIATAEQMLSESKTKIEVIRMQILQLK--THAAS-----------VASR---------
------STDGNDGLPVRIAMLRHHVKIESAIVEGSKNVVRFMAEGKQ---------------------------------
-----------DLTQTICYFNPAIALFDTEARLLPLLSPTTPNHHHPLF------KPHVKSHPSLIYLTLIRI-------
----WCFNNSFIVVILVLPPHHPNTSPT---HPG-KLEVRLVGCQDLLD-------NVPGRSRNMSIQLPATSP-ENR-A
WIRGGSKSFHG------KASNKYNVKPDDLSS------------DASLFNHVPSGVL-----------------------
------LEVALF-----WRFYNNCPHIEIIYTLSH-RNHKVALNMH----MTSQVTFSNPKIERK-PKLQRQKKIFR--N
KGKSFLRAKQMNINIATWSRLMKRAIPPC------NDPNTFSPPSDV-------------------PAQ-----------
------------------EPHPAGKPPLGNPP--VKTDSLNVSLSLSHTHPHDSPPSPITPQ------------------
------------------------------EMMSNIE-------------------------------------------
----------------------------------------------------------------------------LEKP
KPAPRRNKES----------------------------------------------------------------------
-------------------FIQWNQPSSPPKPARRS--------------------------------------------
---------------------------------------NT-----PQAPDSGAKPRQIVMEDFKTIAVLGRGHFGKVLL
TQHKQTGRMYAIKALKKGDIIARDEID---SLMVERRIFECAT-KVKHPFLVNLYACFQTPQHVCFVTEYASGGDL--ML
HIHTDVFNEPRTV-FYTSCVVLGLQYLHENKIVY---RDLKLDNL-----------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------
>Homo_sapiens_PKN2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------MASNPERGEILLTELQGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKRE-----------------
--------------------------IRKELKIKEGAENLRKVTTDK-KSLAYVDNILKKSN------------------
------------------------------------KKLEELHHKLQELNAHIVVSDPEDIT---------------DCP
RTPD-----------------TPNNDPRCSTSNNRLKALQKQLDIELKVKQGAEN---------------------MIQM
YSNGS------------SKDRKLHGTAQQLLQDSKTKIEVIRMQILQA---VQTNE-----------LAFDNA-------
-------KPVISPLELRMEELRHHFRIEFAVAEGAKNVMKLLGSGKVTDR------------------------------
-----------------KALSEAQARFNESSQKLDLLKYSLEQRLNEVP------KNHPKSRIIIEELSLVAAS------
--PTLSPRQSMISTQNQYSTLS-----KPAALTG-TLEVRLMGCQDILE-------NVPGRSKATSVALPGWSPSETRSS
FMSRTSKSKSG--------SSRNLLKTDDLSN------------DVCAVLKLDNTVVGQTSW-KPISNQSWDQKFTLE--
LDRSRELEISVYWRD--WRSLCAVKFLRLEDFLDN-QRHGMCLYLEPQGTLFAEVTFFNPVIERR-PKLQRQKKIFS-KQ
QGKTFLRAPQMNINIATWGRLVRRAIPTV------NHSGTFSPQAPVPTTVP---VVDVRIPQLAPPA------------
------------------SDSTVTKLDFDLEPEPPPAPPRASSLGEID-ESSELRVLDIPGQ------------------
------------------------------DSETVFD-------------------------------------------
----------------------------------------------------------------------------IQND
RNSILPKSQS----------------------------------------------------------------------
-----------------EYKPDTPQSGLEYSGIQE---------------------------------------------
-----------------------------------------------LEDRRSQQRFQFNLQDFRCCAVLGRGHFGKVLL
AEYKNTNEMFAIKALKKGDIVARDEVD---SLMCEKRIFETVN-SVRHPFLVNLFACFQTKEHVCFVMEYAAGGDL--MM
HIHTDVFSEPRAV-FYAACVVLGLQYLHEHKIVY---RDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEF
LAPEVLT-ETSYTRAVDWWGLGVLIYEMLVGESP-FP--GDDEEEVFDSIVNDEVRYPRFLSTEAISIMRR--LLRRNPE
RRLGASEKDAEDVKKHPFFR--LIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPPRE-------PRILSE
EEQEMFRDFDYIADWC-----------
>Pan_troglodytes_PKN2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------MASNPERGEILLTELQGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKRE-----------------
--------------------------IRKELKIKEGAENLRKVTTDK-KSLAYVDNILKKSN------------------
------------------------------------KKLEELHHKLQELNAHIVVSDPEDIT---------------DCP
RTPD-----------------TPNNDPRCSTSNNRLKALQKQLDIELKVKQGAEN---------------------MIQM
YSNGS------------SKDRKLHGTAQQLLQDSKTKIEVIRMQILQA---VQTNE-----------LAFDNA-------
-------KPVISPLELRMEELRHHFRIEFAVAEGAKNVMKLLGSGKVTDR------------------------------
-----------------KALSEAQARFNESSQKLDLLKYSLEQRLNEVP------KNHPKSRIIIEELSLVAAS------
--PTLSPRQSMISTQNQYSTLS-----KPAALTG-TLEVRLMGCQDILE-------NVPGRSKATSVALPGWSPSETRSS
FMSRTSKSKSG--------SSRNLLKTDDLSN------------DVCAVLKLDNTVVGQTSW-KPISNQSWDQKFTLE--
LDRSRELEISVYWRD--WRSLCAVKFLRLEDFLDN-QRHGMCLYLEPQGTLFAEVTFFNPVIERR-PKLQRQKKIFS-KQ
QGKTFLRAPQMNINIATWGRLVRRAIPTV------NHSGTFSPQAPVPTTVP---VVDVRIPQLAPPA------------
------------------SDSTVTKLDFDLEPEPPPAPPRASSLGEID-ESSELRVLDTPGQ------------------
------------------------------DSETVFD-------------------------------------------
----------------------------------------------------------------------------IEND
RNSILPKSQS----------------------------------------------------------------------
-----------------EYKPDTPQSGLEYSGIQE---------------------------------------------
-----------------------------------------------LEDRRSQQRFQFNLQDFRCCAVLGRGHFGKVLL
AEYKHTNEMFAIKALKKGDIVARDEVD---SLMCEKRIFETVN-SVRHPFLVNLFACFQTKEHVCFVMEYAAGGDL--MM
HIHTDVFSEPRAV-FYAACVVLGLQYLHEHKIVY---RDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEF
LAPEVLT-ETSYTRAVDWWGLGVLIYEMLVGESP-FP--GDDEEEVFDSIVNDEVRYPRFLSTEAISIMRR--LLRRNPE
RRLGASEKDAEDVKKHPFFR--LIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPPRE-------PRILSE
EEQEMFRDFDYIADWC-----------
>Pongo_abelii_PKN2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------MASNPEGGEILLTELQGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKRE-----------------
--------------------------IRKELKIKEGAENLRKVTTDK-KSLAYVDNILKKSN------------------
------------------------------------KKLEELHHKLQELNAHIVVSGPEDIT---------------DCP
RTPD-----------------TPNSDPRCSTSNNRLKALQKQLDIELKVKQGAEN---------------------MIQM
YSNGS------------SKDRKLHGTAQQLLQDSKTKIEVIRMQILQA---VQTNE-----------LAFDNA-------
-------KPVISPLELRMEELRHHFRIEFAVAEGAKNVMKLLGSGKVTDR------------------------------
-----------------KALSEAQARFNESSQKLDLLKYSLEQRLNELP------KNHPKSSIIIEELSLVAAS------
--PTLSPRQSMISTQNQYSTLS-----KPAALTG-TLEVRLMGCQDILE-------NVPGRSKATSVALPGWSPSETRSS
FMSRTSKSKSG--------SSRNLLKTDDLSN------------DVCAVLKLDNTVVGQTSW-KPISNQSWDQKFTLE--
LDRSRELEISVYWRD--WRSLCAVKFLRLEDFLDN-QRHGMCLYLEPQGTLFAEVTFFNPVIERR-PKLQRQKKIFS-KQ
QGKTFLRAPQMNINIATWGRLVRRAIPTV------NHSGTFSPQAPVPTTVP---VVDVRIPELAPPA------------
------------------SDSTVTKLDFDLEPEPPPAPPRASSLGEID-ESSELRVLDTPGQ------------------
------------------------------DSETVFD-------------------------------------------
----------------------------------------------------------------------------IEND
RNSILPKSQS----------------------------------------------------------------------
-----------------EYKPDTPQSGLEYSGIQE---------------------------------------------
-----------------------------------------------LEDRRSQQRFQFNLQDFRCCAVLGRGHFGKVLL
AEYKHTNEMFAIKALKKGDIVARDEVD---SLMCEKRIFETVN-SVRHPFLVNLFACFQTKEHVCFVMEYAAGGDL--MM
HIHTDVFSEPRAV-FYAACVVLGLQYLHEHKIVY---RDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEF
LAPEVLT-ETSYTRAVDWWGLGVLIYEMLVGESP-FP--GDDEEEVFDSIVNDEVRYPRFLSTEAISIMRR--LLRRNPE
RRLGASEKDAEDVKKHPFFR--LIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPPRE-------PRILSE
EEQEMFRDFDYIADWC-----------
>Macaca_mulatta_PKN2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------GDSRSLPFSENVSAVQKLDFSDTVVQQKLDDIKDRIKRE-----------------
--------------------------IRKELKIKEGAENLRKVTTDK-KSLAYVDNILKKSN------------------
------------------------------------KKLEELHHKLQELNAHIVVSDPEDIT---------------DCP
RTPD-----------------TPNSDPRCSTSNNRLKALQKQLDIELKVKQGAEN---------------------MIQM
YSNGS------------SKDRKLHGTAQQLLQDSKTKIEVIRMQILQA---VQTNE-----------LAFDNA-------
-------KPVISPLELRMEELRHHFRIEFAVAEGAKNVMKLLGSGKVTDR------------------------------
-----------------KALSEAQARFNESSQKLDLLKYSLEQRLNELP------KNHPKSSIIIEELSLVAS-------
--PTLSPRQSMISTQNQYSTLS-----KPAALTG-TLEVRLMGCQDILE-------NVPGRSKATSVALPGWSPSETRSS
FMSRTSKSKSG--------SSRNLLKTDDLSN------------DVCAVLKLDNTVVGQTSW-KPISNQSWDQKFTLE--
LDRSRELEISVYWRD--WRSLCAVKFLRLEDFLDN-QRHGMCLYLEPPGLYLQRVTFFNPVIERR-PKLQRQKKIFS-KQ
QGKTFLRAPQMNINIATWGRLVRRAIPTV------NHSGTFSPQAPVPTTVP---VVDVRIPELAPPA------------
------------------SDSTVTKLDFDLEPEPPPAPPRASSLGEID-ESSELR-------------------------
------------------------------DSETVFD-------------------------------------------
----------------------------------------------------------------------------IEND
RNSILPKSQS----------------------------------------------------------------------
-----------------EYKPDTPR-ALEYSGIQE---------------------------------------------
-----------------------------------------------LED--SQQRFQFNLQDFRCCAVLGRGHFGKVLL
AEYKHTNEMFAIKALKKGDIVARDEVD---SLMCEKRIFETVN-SVRHPFLVNLFACFQTKEHVCFVMEYAAGGDL--MM
HIHTDVFSEPRAV-FYAACVVLGLQYLHEHKIVY---RDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEF
LAPEVLT-ETSYTRAVDWWGLGVLIYEMLVGESP-FP--GDDEEEVFDSIVNDEVRYPRFLSTEAISIMRR--LLRRNPE
RRLGASEKDAEDVKKHPFFR--LIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPPRE-------PRILSE
EEQEMFRDFDYIADWC-----------
>Mus_musculus_PKN2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------MASNPDRGEILLTELQGDSRTLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKRE-----------------
--------------------------IRKELKIKEGAENLRKVTTDK-KNLAYVDNILKKSN------------------
------------------------------------KKLEELHHKLQELNAHIVVSDPEDST---------------DCP
RTPD-----------------TPNSDSRSSTSNNRLMALQKQLDIELKVKQGAEN---------------------MIQM
YSNGS------------SKDRKLHGTAQQLLQDSKTKIEVIRMQILQA---VQTNE-----------LAFDNA-------
-------KPVISPLELRMEELRHHFKIEFAVAEGAKNVMKLLGSGKVTDR------------------------------
-----------------KALSEAQARFNESSQKLDLLKYSLEQRLNELP------RNHPKSSVVIEELSLVAS-------
--PTLSPRQSMLSTQNQYSTLS-----KPAALTG-TLEVRLMGCQDILE-------NVPGRSKATSVALPGWSPSDNRSS
FMSRTSKSKSG--------SSRNLLKTDDLSN------------DVCAVLKLDNTVVGQTSW-KPISNQSWDQKFTLE--
LDRSRELEISVYWRD--WRSLCAVKFLRLEDFLDN-QRHGMCLYLEPQGTLFAEVTFFNPVIERR-PKLQRQKKIFS-KQ
QGKTFLRAPQMNINIATWGRLVRRAIPTV------NHSGTFSPQTPVPATVP---VVDARIPDLAPPA------------
------------------SDSTVTKLDFDLEPEPPPAPPRASSLGETD-ESSELRVLDIPGQ------------------
------------------------------GSETVFN-------------------------------------------
----------------------------------------------------------------------------IEND
RNNLRPKSKS----------------------------------------------------------------------
-----------------EYELSIPDSGRSCWGVGE---------------------------------------------
-----------------------------------------------LDDKRAQQRFQFSLQDFRCCAVLGRGHFGKVLL
AEYKHTNEMFAIKALKKGDIVARDEVD---SLMCEKRIFETVN-SVRHPFLVNLFACFQTKEHVCFVMEYAAGGDL--MM
HIHTDVFSEPRAV-FYAACVVLGLQYLHEHKIVY---RDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEF
LAPEVLT-ETSYTRAVDWWGLGVLIYEMLVGESP-FP--GDDEEEVFDSIVNDEVRYPRFLSTEAISIMRR--LLRRNPE
RRLGAGEKDAEDVKKHPFFR--LTDWSALMDKKVKPPFVPTIRGREDVSNFDDEFTSEAPILTPPRE-------PRILLE
EEQEMFHDFDYVADWC-----------
>Rattus_norvegicus_PKN2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------MASNPDRGEILLTELQGDSRPLPFSENVSAVQKLDFSDTIVQQKLDDVKDRIKRE-----------------
--------------------------IRKELKIKEGAENLRKVTTDK-KNLAYVDNILKKSN------------------
------------------------------------KKLEELHHKLQELNAHIVVSDPEDSA---------------DCP
RTPD-----------------TPNSDSRSSTSNNRLMALQKQLDIELKVKQGAEN---------------------MIQM
YSNGP------------SKDRKLHGTAQQLLQDSKTKIEVIRMQILQA---VQTNE-----------LAFDNA-------
-------KPVISPLELRMEELRHHFRIEFAVAEGAKNVMKLLGSGKVTDR------------------------------
-----------------KALSEAQARFNESSQKLDLLKYSLEQRLNELP------KNHPKSSVVIEELSLVAS-------
--PTLSPRQSMLSTQNQYSTLS-----KPAALTG-TLEVRLMGCQDILE-------NVPGRSKATSVALPGWSPSENRSS
FMSRTSKSKSG--------SSRNLLKTDDLSN------------DVCAVLKLDNTVVGQTIW-KPISNQSWDQKFTLE--
LDRSRELEISVYWRD--WRSLCAVKFLRLEDFLDN-QRHGMCLYLEPQGTLFAEVTFFNPVIERR-PKLQRQKKIFS-KQ
QGKTFLRAPQMNINIATWGRLVRRAIPTV------NHSGTFSPQTPVPATVP---VVDARTPELAPPA------------
------------------SDSTVTKLDFDLEPEAPPAPPRASSLGEID-DSSELRVLDIPGQ------------------
------------------------------GSETVFD-------------------------------------------
----------------------------------------------------------------------------IEND
RNNMRPKSKS----------------------------------------------------------------------
-----------------EYELNIPDSSRSCWSVGE---------------------------------------------
-----------------------------------------------LEDKRSQQRFQFNLQDFRCCAVLGRGHFGKVLL
AEYKHTNEMFAIKALKKGDIVARDEVD---SLMCEKRIFETVN-SVRHPFLVNLFACFQTKEHVCFVMEYAAGGDL--MM
HIHTDVFSEPRAV-FYAACVVLGLQYLHEHKIVY---RDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEF
LAPEVLT-ETSYTRAVDWWGLGVLIYEMLVGESP-FP--GDDEEEVFDSIVNDEVRYPRFLSTEAISIMRR--LLRRNPE
RRLGAGEKDAEDVKKHPFFR--LTDWSALLDKKVKPPFVPTIRGREDVSNFDDEFTSEAPILTPPRE-------PRILLE
EEQEMFRDFDYVADWC-----------
>Oryctolagus_cuniculus_PKN2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------MASNPERGEILLTELQGDSRSLPFPENVSAVQKLDFSDTMVQQKLDDIKDRIKRE-----------------
--------------------------IRKELKIKEGAENLRKVTTDK-KSLAYVDNILKKSN------------------
------------------------------------KKLEELHHKLQELNAHIVVSDPEDVT---------------DCP
RTPD-----------------TPNSDPRSSTSNNRLMALQKQLDIELKVKQGAEN---------------------MIQM
YSNGS------------SKDRKLHGTAQQLLQDSKTKIEVIRMQILQA---VQTNE-----------MAFDNA-------
-------KPVISPLELRMEELRHHFRIEFAVAEGAKNVMKLLGSGKVTDR------------------------------
-----------------KALSEAQARFNESSQKLDLLKYSLEQRLNELP------KNHPKSSIIIEELSLVAS-------
--PTLSPRQSMISTQNQYSTLS-----KPAALTG-TLEVRLMGCQDILE-------NVPGRSKATSVALPGWSPSETRSS
FMSRTSKSKSG--------SSRNLLKTDDLS------------NDVCAVLKLDNTVVGQTSW-KPISNQSWDQKFTLE--
LDRSRELEISVYWRD--WRSLCAVKFLRLEDFLDN-QRHGMCLYLEPQGTLFAEVTFFNPVIERR-PKLQRQKKIFS-KQ
QGKTFLRAPQMNINIATWGRLVRRAIPTV------NHSGTFSPQTPVPASVA---VVDVRIPEIAPPA------------
------------------SDSTVTKLDFDLEPEPPPAPPRASSLGEID-ESSELRVLDTAGQ------------------
------------------------------DSETGFD-------------------------------------------
----------------------------------------------------------------------------IEND
RNSILPKSQS----------------------------------------------------------------------
-----------------EYEPDIPQSGLEYGDIRE---------------------------------------------
-----------------------------------------------LENRRSQQRFQFNLQDFRCCAVLGRGHFGKVLL
AEYKNTNEMFAIKALKKGDIVARDEVD---SLMCEKRIFETVN-SVRHPFLVNLFACFQTKEHVCFVMEYAAGGDL--MM
HIHTDVFSEPRAV-FYAACVVLGLQYLHEHKIVY---RDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEF
LAPEVLT-ETSYTRAVDWWGLGVLIYEMLVGESP-FP--GDDEEEVFDSIVNDEVRYPRFLSTEAISIMRR--LLRRNPE
RRLGAGEKDAEDVKKHPFFR--LIDWSALMDKKVKPPFVPTIRGREDVSNFDDEFTSEAPILTPPRE-------PRILSE
EEQELFRDFDYIADWC-----------
>Canis_familiaris_PKN2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------MALQKQLDIELKVKQGAEN---------------------MIQM
YSNGS------------SKDRKLHGTAQQLLQDSKTKIEVIRMQILQA---VQTNE-----------LAFDNA-------
-------KPVISPLELRMEELRHHFRIEFAVAEGAKNVMKLLGSGKVTDR------------------------------
-----------------KALSEAQARFNESSQKLDLLKYSLEQRLNELP------KNHPKSSIIIEELSLVAS-------
--PTLSPRQSMISTQNQYSTLS-----KPAALTG-TLEVRLMGCQDILE-------NVPGRSKATSVALPGWSPSETRSS
FMSRTSKSKSG--------SSRNLLKTDDLS------------NDVCAVLKLDNTVVGQTSW-KPISNQSWDQKFTLE--
LDRSRELEISVYWRD--WRSLCAVKFLRLEDFLDN-QRHGMCLYLEPQGTLFAEVTFFNPVIERR-PKLQRQKKIFS-KQ
QGKTFLRAPQMNINIATWGRLVRRAIPTV------NHSGTFSPQAPVPTTVP---VVDVRIPELAPPA------------
------------------SDSTVTKLDFDLEPEPPPAPPRDSSLGEID-ESAKLRDLDTPAQ------------------
------------------------------DSETVFD-------------------------------------------
----------------------------------------------------------------------------IEND
RNSILPKSPS----------------------------------------------------------------------
-----------------EYEPNIPQPGLGYSGIRE---------------------------------------------
-----------------------------------------------LEDRRSQQMFQFNLQDFRCCAVLGRGHFGKVLL
AEYKHTNEMFAIKALKKGDIVARDEVD---SLMCEKRIFETVN-SVRHPFLVNLFACFQTKEHVCFVMEYAAGGDL--MM
HIHTDVFSEPRAV-FYAACVVLGLQYLHEHKIVY---RDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEF
LAPEVLT-ETSYTRAVDWWGLGVLIYEMLVGESP-FP--GDDEEEVFDSIVNDEVRYPRFLSTEAISIMRR--LLRRNPE
RRLGAGEKDAEDVKKHPFFR--LIDWSALMDKKVKPPFVPTIRGREDVSNFDDEFTSEAPILTPPRE-------PRILSE
EEQEMFRDFDYIADWC-----------
>Felis_catus_PKN2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------LVSCLLRKELNVIRYNGDSRSLPFSENVSAVQKLDFSDTVVQQKLDDIKDRIKRE-----------------
--------------------------IRKELKIKEGAENLRKVTTDK-K-LAYVDNILKKSN------------------
------------------------------------KKLEELHHKLQELNAHIVVSDPEDVT---------------DCP
RTPD-----------------TPSSDPRCSTSNNRLMALQKQLDIELKVKQGAEN---------------------MIQM
YSNGS------------SKDRKLHGTAQQLLQDSKTKIEVIRMQILQA---VQTNE-----------LAFDNA-------
-------KPVISPLELRMEELRHHFRIEFAVAEGAKNVMKLLGSGKVTDR------------------------------
-----------------KALSEAQARFNESSQKLDLLKYSLEQRLNELP------KNHPKSSIIIEELSLVAS-------
--PTLSPRQSMISTQNQYSTLS-----KPAALTG-TLEVRLMGCQDILE-------NVPGRSKATSVALPGWSPSETRSS
FMSRTSKSKSG--------SSRNLLKTDDLS------------NDVCAVLKLDNTVVGQTSW-KPISNQSWDQKFTLE--
LDRSRELEISVYWRD--WRSLCAVKFLRLEDFLDN-QRHGMCLYLEPQGTLFAEVTFFNPVIERR-PKLQRQKKIFS-KQ
QGKTFLRAPQMNINIATWGRLVRRAIPTV------NHSGTFSPQASVPATVP---VVDVRIPELVSSI------------
------------------SDSTVTKLDFDLEPEPPPAPPRDSSLGEID-ESAELRDSDTPRQ------------------
------------------------------DSEAVFA-------------------------------------------
----------------------------------------------------------------------------IEND
RNSILPKSQS----------------------------------------------------------------------
-----------------EYEPDIPQPGLGYSGVRE---------------------------------------------
-----------------------------------------------LEDRRSQQMFQFNLQDFRCCAVLGRGHFGKVLL
AEYKHTNEMFAIKALKKGDIVARDEVD---SLMCEKRIFETVN-SVRHPFLVNLFACFQTKEHVCFVMEYAAGGDL--MM
HIHTDVFSEPRAV-FYAACVVLGLQYLHEHKIVYSLNRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEF
LAPEVLT-ETSYTRAVDWWGLGVLIYEMLVGESP-FP--GDDEEEVFDSIVNDEVRYPRFLSTEAISIMRR--LLRRNPE
RRLGAGEKDAEDVKKHPFFR--LIDWSALMDKKVKPPFVPTIRGREDVSNFDDEFTSEAPILTPPRE-------PRILSE
EEQEMFRDFDYIADWC-----------
>Bos_taurus_PKN2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------MASNPERGEILLTELQGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKRE-----------------
--------------------------IRKELKIKEGAENLRKVTTDK-KSLAYVDNILKKSN------------------
------------------------------------KKLEELHHKLQELNAHIVVSDPEDVT---------------DCP
RTPD-----------------TPSSDSRCSTSNNRLMALQKQLDIELKVKQGAEN---------------------MIQM
YSNGS------------SKDRKLHGTAQQLLQDSKTKIEVIRMQILQA---VQTNE-----------LAFDNA-------
-------KPVISPLELRMEELRHHFRIEFAVAEGAKNVMKLLGSGKVTDR------------------------------
-----------------KALSEAQARFNESSQKLDLLKYSLEQRLNELP------KNHPKSSIIIEELSLVAS-------
--PTLSPRQSMISTQNQYSTLS-----KPAALTG-TLEVRLMGCQDILE-------NVPGRSKAASVALPGWSPSETRSS
FMSRTSKSKSG--------SSRNLLKTDDLS------------NDVCAVLKLDNTVVGQTSW-KPISNQSWDQKFTLE--
LDRSRELEISVYWRD--WRSLCAVKFLRLEDFLDN-QRHGMCLYLEPQGTLFAEVTFFNPVIERR-PKLQRQKKIFS-KQ
QGKTFLRAPQMNINIATWGRLVRRAIPTV------NHSGTFSPQAPVPATVP---VVDVHIPELAPPA------------
------------------SDSTVTKLDFDLEPEPPPAPPRDSSLGEID-ESA--RDLDTPGQ------------------
------------------------------DSETVFD-------------------------------------------
----------------------------------------------------------------------------TEND
RNRILPKSQS----------------------------------------------------------------------
-----------------EYEPDIPQSGLEYSGIHE---------------------------------------------
-----------------------------------------------LEDRRSQQMFQFSLQDFRCCAVLGRGHFGKVLL
AEYKHTNEMFAIKALKKGDIVARDEVD---SLMCEKRIFETVN-SVRHPFLVNLFACFQTKEHVCFVMEYAAGGDL--MM
HIHTDVFSEPRAV-FYAACVVLGLQYLHEHKIVY---RDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEF
LAPEVLT-ETSYTRAVDWWGLGVLIYEMLVGESP-FP--GDDEEEVFDSIVNDEVRYPRFLSTEAISIMRR--LLRRNPE
RRLGAGEKDAEDVKKHPFFR--LIDWSALMDKKVKPPFVPTIRGREDVSNFDDEFTSEAPILTPPRE-------PRILSE
EEQEMFRDFDYIADWC-----------
>Loxodonta_africana_PKN2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------GDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKRE-----------------
--------------------------IRKELKIKEGAENLRKVTTDK-KSLAYVDNILKKSN------------------
------------------------------------KKLEELHHKLQELNAHIVVSDSEDVT---------------DCP
RTPD-----------------TPNNDPRCSTSNNRLMALQKQLDIELKVKQGAEN---------------------MIQM
YSNGS------------SKDRKLHGTAQQLLQDSKTKIEVIRMQILQA---VQTNE-----------LAFDNA-------
-------KPVISPLELRMEELRHHFKIEFAVAEGAKNVMKLLGSGKVTDR------------------------------
-----------------KALSEAQARFNESSQKLDLLKYSLEQRLNELP------KNHPKSSIIIEELSLVAS-------
--PTLSPRQSMISTQNQYSTLS-----KPAALTG-TLEVRLMGCQDILE-------NVPGRSKAASVALPGWSPSETRSS
FMSRTSKSKSG--------SSRNLLKTDDLSSSV---------NDICAFLKLDNTVVGQTSW-KPISNQSWDQKFTLE--
LDRSRELEISVYWRD--WRSLCAVKFLRLEDFLDN-QRHGMCLYLEPQGTLFAEVTFFNPVIERR-PKLQRQKKIFS-IQ
QGKTFLRAPQMNINIATWGRLVRRAF--L------NHTGTFSPPASVPAAVP---AVDVRIPELAPPA------------
------------------SDPTVTKLDFDFEPELPLAPLRASSLGEID-ESTELRVLDEPNQ------------------
------------------------------DSASTFD-------------------------------------------
----------------------------------------------------------------------------IEND
RNSILQKSQP----------------------------------------------------------------------
-----------------EYELDIPQSGLDYSDIRE---------------------------------------------
-----------------------------------------------LEDRRSQQRFQFNLQDFRCCAVLGRGHFGKVLL
AEYKHTNEMFAIKALKKGDIVARDEVD---SLMCEKRIFETVN-SVRHPFLVNLFACFQTKEHVCFVMEYAAGGDL--MM
HIHTDVFSEPRAV-FYAACVVLGLQYLHEHKIVYSLNRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEF
LAPEVLT-ETSYTRAVDWWGLGVLIYEMLVGESP-FP--GDDEEEVFDSIVNDEVRYPRFLSTEAISIMRR--LLRRNPE
RRLGASEKDAEDVKKHPFFR--LIDWNTLMDKKVKPPFVPTIRGREDVSNFDDEFTSEAPILTPPRE-------PRILSE
EEQEMFRDFDYIADWC-----------
>Monodelphis_domestica_PKN2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------MASNTERGEILLTELQGDARSLLLPENVSTGQKLDFSDTMVQQKLDDIKDRIKRE-----------------
--------------------------IRKELKIKEGAENLRKVTTDK-KNLAYVDNILKKSN------------------
------------------------------------KKLEELHHKLQELNAHIVVTDPEDLT---------------DCP
RTPD-----------------TPNSDPRCATSN-KLMALKKQLDIELKVKQGAEN---------------------MIQM
YSNGS------------SKDRKLLATAQQLLQDSKTKIEVIRMQILQA---VQTNE-----------LAFDNA-------
-------KPVISPLELRMEELRHHFRIEFAVAEGAKNVMKLLGSGKVADR------------------------------
-----------------KALSEAQARFNESSQKLDLLKYSLEQRLSELP------KNHPKSSIIIEELSLVGS-------
--PTLSPRQSVISTQNQYSTLS-----KPAALTG-TLEVRLMGCQDILE-------NVPGRSKATSVTLPGWSPSETRSS
FMSRTSKSKSG--------SSRNLLKTDDLSN------------DICAVLKLDNTVVGQTSW-KPISNQSWDQKFTLE--
LDRSRELEISVYWRD--WRSLCAVKFLRLEDFLDN-QRHGMCLYLEPQGTLFAEVTFFNPVIERR-PKLQRQKKIFS-KQ
QGKTFLRAPQMNINIATWGRLVRRAIPTV------NHSGTFSPQAPGPTTVP---VVDVRIPELSPPA------------
------------------SDSTVTKLDFELEPEAPPAPPRTSSFGEIH-EPSELRVLDVSGQ------------------
------------------------------DSETTFN-------------------------------------------
----------------------------------------------------------------------------FEND
RNSIVPKNQP----------------------------------------------------------------------
-----------------EYEPPVLQSSLEYGGVQE---------------------------------------------
-----------------------------------------------PEERRSPQRFQFSLQDFRCCAVLGRGHFGKVLL
AEYKNTNEMFAIKALKKGDIVARDEVD---SLMCEKRIFETVN-SVRHPFLVNLFACFQTKEHVCFVMEYAAGGDL--MM
HIHTDVFSEPRAV-FYAACVVLGLQYLHEHKIVY---RDLKLDNLLLDTEGFVKIADFGLCKEGMGFGDRTSTFCGTPEF
LAPEVLT-ETSYTRAVDWWGLGVLIYEMLVGESP-FP--GDDEEEVFDSIVNDEVRYPRFLSTEAISIMRR--LLRRNPE
RRLGAGEKDAEDVKKHPFFR--LIDWNALLAKKVKPPFVPTIRGREDR--------------IPLSC-------ACLKWK
EEQLVI---------------------
>Ornithorhynchus_anatinus_PKN2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------QGDTRSLLLPDNVSAGQKLDFSDTMVQQKLDDIKDRIKRE-----------------
--------------------------IRKELKIKEGAENLRKVTTDK-KNLAYVDNILKKSN------------------
------------------------------------KKLEELHHRLQELNAHIVVTDPEDLTD--------------SCL
RTPDPCL-------------HTPESQSNGNVSANPLIPRKSQLCFRLTVHWGSNN---------------------SLAM
YSSGS------------SDDRKLLATAQQLLQDSKTKIEVIRMQILQA---IQTNE-----------LAFDNA-------
-------KPVISPLELRMEELRHHFRIEFAVAEGAKNVMKLLGSGKVTDR------------------------------
-----------------KALSEAQARFNESSQKLDLLKYSLEQRLNELP------KNHPKSSIIIEELSLVSS-------
--PTLSPRQSMISTQNQYSTLS-----KPAALTG-TLEVRLMGCQDILE-------NVPGRSKATSVTLPGWSPSEARSS
FMSRTSKSKSG--------SSRNLLKTDDLSR-----------DEVCAVLKLDNTVVGQTSW-KPISNQSWDQKFTLE--
LDRSRELEISVYWRD--WRSLCAVKFLRLEDFLDN-QRHGMCLYLEPQGTLFAEVTFFNPVIERR-PKLQRQKKIFS-KQ
QGKTFLRAPQMNINIATWGRLVRRAIPTV------NHSGTFSPQAPVSAPVP---VVDVRIPELAAPA------------
------------------SDSTVTKLDFELEPDPPTAPPRASSLGEIHDSSSESKVLDPPVK------------------
------------------------------DSETVFD-------------------------------------------
----------------------------------------------------------------------------IDNG
RN-IVPKSQPE---------------------------------------------------------------------
----------------IIYEPDIPQSGLEFSPVRE---------------------------------------------
-----------------------------------------------PEDRRSQQRFQFSLQDFRCCAVLGRGHFGKVLL
AEYKNTNEMFAIKALKKGDIVARDEAD---SLMCEKRIFETVN-SVRHPFLVNLFACFQTKDHVCFVMEYAAGGDL--MM
HIHTDVFSEPRAV-FYAACVVLGLQYLHEHKIVYSPNRDLKLDNLLLDTEGFVKIADFGLCKEVMECPDRRLTRCCSFLC
FPPETFT-ETNLNSRLTFW-FGLKVVETVELHSP-FP--GDDEEEVFDSIVNDEVRYPRFLSTEAISIMRR--LLRRNPE
RRLGAAEKDAEDVKKHPFFRVSMKDWNALMAKKLKPPFVPTIRGREDVSNFDDEFTSEAPILTPPRE-------PRILSE
EEQEMFTDFDYIADWC-----------
>Gallus_gallus_PKN2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------MVQQKLDEIKDQIKRE-----------------
--------------------------IRKELKIKEGAENLRKVTTDK-KNLAYVDNILKKSN------------------
------------------------------------KKLEDLHHKLQELNAHIVVTDPEDVA---------------DCP
RTPD-----------------TPNSDPR-FPTNNRLMALKKQLDIELKVK