>Homo_sapiens_S1PR1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------MGPTSVPLVKAHRSSVSDYV--------NYDIIVRHYNYTGKLNIS
-------------------------------------ADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKF-HRPM
YYFIGNLALSDLLAGVAYT----ANLLLSGATTYKLTPA-------QWFLREGSMF------VALSASVFSLLAIAIERY
ITMLKMKLHNGSNN--FRLFLLISACWVISLILGG-LPIMG-----------WNCISA------------------LSSC
STVLPLY-----HKHYILFCTTV-FTLLLLSIVILYCRIYS---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
LVRTRSRRLTFRK-------------------------------------------------------------------
NISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLD-VGCKVKTCDILF--------------------RAEYFLV
LAVLNSGTNP-------------------------IIYTLTNKEMRRAFIRIMS-----CCKCPSGD-------------
---------SAGKFKRP---IIAGMEFSRSKS-----------------------------DNSSHPQKDEGDNPETIMS
---SGNVNSSS---------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Macaca_mulatta_S1PR1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------MGSTSVPLVKALRSSVSDYV--------NYDIIVRHYNYTGKLNTS
-------------------------------------ADRENSIKLTSVVFILICCFIILENIFVLLTIWKTKKF-HRPM
YYFIGNLALSDLLAGVAYT----ANLLLSGATTYKLTPA-------QWFLREGSMF------VALSASVFSLLAIAIERY
ITMLKMKLHNGSNN--FRLFLLISACWVISLILGG-LPIMG-----------WNCISA------------------LPSC
STVLPLY-----HKHYILFCT-----------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------VFIACWAPLFILLLLD-VGCKVKTCDILF--------------------RAEYFLV
LAVLNSGTNP-------------------------IIYTLTNKEMRRAFIRIMS-----CCKCPSGD-------------
---------SAGKFKRP---IIAGMEFSRSKS-----------------------------DNSSHPQKDDGDNPETIMS
---SGNVNSSS---------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Mus_musculus_S1PR1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------MVS-TSIPEVKALRSSVSDYG--------NYDIIVRHYNYTGKLNIG
-------------------------------------AEKDHGIKLTSVVFILICCFIILENIFVLLTIWKTKKF-HRPM
YYFIGNLALSDLLAGVAYT----ANLLLSGATTYKLTPA-------QWFLREGSMF------VALSASVFSLLAIAIERY
ITMLKMKLHNGSNS--SRSFLLISACWVISLILGG-LPIMG-----------WNCISS------------------LSSC
STVLPLY-----HKHYILFCTTV-FTLLLLSIVILYCRIYS---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
LVRTRSRRLTFRK-------------------------------------------------------------------
NISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLD-VGCKAKTCDILY--------------------KAEYFLV
LAVLNSGTNP-------------------------IIYTLTNKEMRRAFIRIVS-----CCKCPNGD-------------
---------SAGKFKRP---IIPGMEFSRSKS-----------------------------DNSSHPQKDDGDNPETIMS
---SGNVNSSS---------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Canis_familiaris_S1PR1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------MGSTSVPLVKALRSPVSDYV--------NYDIIVRHYNYTGKLNTS
-------------------------------------ADKENGIKMSSVVFILICCFIILENIFVLLTIWKTKKF-HRPM
YYFIGNLALSDLLAGVAYT----ANLLLSGATTYKLTPA-------QWFLREGSMF------VALSASVFSLLAIAIERY
ITMLKMKLHNGSNS--FRSFLLISACWVISLVLGG-LPIMG-----------WNCIGA------------------LASC
STVLPLY-----HKHYILFCTTV-FTLLLLAIVILYCRIYS---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
LVRTRSRRLTFRK-------------------------------------------------------------------
NISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLD-VGCKVKTCDILF--------------------RAEYFLV
LAVLNSGTNP-------------------------IIYTLTNKEMRRAFIRILS-----CCKCPGGD-------------
---------PAGKFKRP---IIAGVEFSRT--------SLSMVA-----------------EICLK----KSSLSTVWYP
---AGSLVSQEEQTSKTR--------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Felis_catus_S1PR1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------MGSTSVPLVKTHRSSVSDYV--------NYDIIVRHYNYTGKLNVS
-------------------------------------AD-ENGIKLSSVVFILICCFIILENIFVLLTIWKTKKF-HRPM
YYFIGNLALSDLLAGVAYT----ANLLLSGATTYKLTPA-------QWFLREGSMF------VALSASVFSLLAIAIERY
ITMLKMKLHNGSNS--FRSFLLISACWVISLILGG-FPIMG-----------WNCINM------------------LASC
STVLPLY-----HKHYILFCTTV-FTLLLLAIVILYCRIYS---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
LVRTRSRRLTFRK-------------------------------------------------------------------
NISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLD-VGCKVKTCDILF--------------------RAEYFLV
LAVLNSGTNP-------------------------IIYTLTNKEMRRAFIRILS-----CCKCPSED-------------
---------SAGKFKRP---IIAGMEFSRSKS-----------------------------DNSSHPQKDDGDNPETIMS
---SGNVNSSS---------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Pteropus_vampyrus_S1PR1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------MGSTSIPLVKALRSPVSDYV--------NYDIIVRHYNYTGKLNLG
-------------------------------------TDKDSSIKVTSVVFILICCFIILENIFVLLTIWKTKKF-HRPM
YYFIGNLALSDLLAGVAYA----VNLLFSGANTYKLTPA-------QWFLREGSMF------VALSASVFSLLAIAIERY
ITMLKMKLHNESNS--SRSFLLISACWIISLILGG-LPIMG-----------WNCISM------------------LPSC
STVLPLY-----HKHYILFCTTV-FTVLLLSIVILYCRIYS---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
LVRTRSRRLTFRK-------------------------------------------------------------------
NTSKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLD-VGCKVKTCDILF--------------------KVEYFLV
LAVLNSGTNP-------------------------IIYTLTNKEMRRAFIKIMS-----CCKCPRGD-------------
---------TTGKFKRP---IIAGVEFSRSKS-----------------------------DNSSHPQKDDGDNPETIMS
---SGNVNSSS---------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Gallus_gallus_S1PR1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------MSSGTTAPVRVVSSLTNTDV--------N-YVIKEHYNYTGKLNEN
-------------------------------------ADS--GIKVTSVVFIIICCFIILENIFVLLTIWKTKKF-HRPM
YYFIGNLALSDLLAGVAYT----ANLLLSGHKTYSLTPS-------QWFVREGSMF------VALSASVFSLLAIAIERY
ITMLKMKLHNGSNS--FRSFLLISACWVISVILGG-LPIMG-----------WNCISL------------------LSNC
STVLPLY-----HKHYILFCTTV-FTGLLLSIVVLYCRIYS---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
MVRTRSRRLTFRK-------------------------------------------------------------------
NITKATRSSEKSLALLKTVIIVLSAFIACWAPLFILLLLD-VGCRVKTCPILY--------------------KAEYFLV
LAVLNSATNP-------------------------IIYTLTNKEMRRAFIKILC-----CCKCPPTD-------------
---------SGTKFKRP---IIGGMEFSRSKS-----------------------------DNSSHPQKEEGDRPETIMS
---SGNVTSSS---------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Xenopus_tropicalis_S1PR1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------MTPTSAT------QRRNEYY--------DHEIIIEHYNYTGKYKGN
-------------------------------------LST--DIKPTSIIFIIICCFIVLENILVLLTIWRTKKF-HRPM
YYFIGNLALSDLLAGTAYT----ANILLSGPHTYKLTPV-------EWLIREGSMF------VALSASVFSLVAIAIERY
ITMLKMKLHNGSKS--SRSFLLISGCWILSLFLGG-LPIMG-----------WNCIKQ------------------ISAC
STVLPLY-----HKHYILFCTTI-FCALLMAIVILYARIYF---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
LVRTRSRSLTFKR-------------------------------------------------------------------
NLARPSRSSEKSMALLKTVIIVLSVFILCWSPLFIFLLLD-FGCKVKTCPVLF--------------------KAEYFLS
LAVLNSATNP-------------------------IIYTLTNREMRRAFLKMAC-----CSHCSIFG-------------
---------SSSKVKRP---IITGMEFSRSKS-----------------------------DNSSHPQKDEGEYPVTLMS
---SGNVTSSS---------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Danio_rerio_S1PR1_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------MDDLIARHYNFTGKFRKV
-------------------------------------HKD-PGLKADSVVFIIVCCFIILENVLVLLTIWRTKKF-HKPM
YYFIGNLALSDLLAGVVYT----ANILLSGANTYKLTPT-------QWFFREGSMF------VALAASVFSLLAIAIERH
LTMLKMKLHNNGKT--CRVFMLISTVWFIAAILGG-LPVMG-----------WNCIDS------------------INNC
STVLPLY-----HKAYILFCTTV-FSVILMAIVILYARIYA---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
LVRTRSRKLVFRKVANG-------------------------------------------------------------RG
SN----KSSEKSMALLKTVIIVLSCFIACWAPLFILLLLD-VACQTLTCSILY--------------------KAEWFLA
LAVLNSAMNP-------------------------LIYTLTSNEMRRAFIK-MLN----CGVCVQPS-------------
-----------GKFSRP----IMGAEFSRSKS-----------------------------DNSSHPNKDEPEYSPRET-
IVSSGNITSSS---------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Takifugu_rubripes_S1PR1_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------VGPTDQTRKRRQASVEPLY--------YSDLISKHYNYTGKFRKT
-------------------------------------QQD-SGLKADSVVFIIVCCFIILENILVLTTIWRTKKF-HKPM
YYFIGNLALSDLLAGVVYT----ANILLSGANTYKLTPT-------QWFFREGSMF------VALAASVFSLLAIAIERH
LTMLKMKLHNNGNT--CRVFLLISAVWMVAAVLGG-LPVMG-----------WNCIQI------------------MTQC
STVLPLY-----HKTYILFCTTV-FSIILMAIVVLYARIYA---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
LVRTRSRKLVFRKVSNG-------------------------------------------------------------RG
NSGANVKSSEKSMALLKTVFIVLSCFIACWAPLFILLLLD-TACQTLSCPILY--------------------KAEWFLA
LAVLNSAMNP-------------------------LIYTLTSNEMRRAFLKTLLC----CTSCLRSK-------------
-----------VKFSSP----IMGAEFSRSKS-----------------------------DNSSHPNREDGEQSPRGTR
TASSGTITLCS---------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Tetraodon_nigroviridis_S1PR1_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------DLISKHYNYTGKFRKT
-------------------------------------QED-SGLKADSVVFIIVCCFIILENILVLTTIWRTKKF-HKPM
YYFIGNLALSDLLAGVVYT----ANILLSGANTYKLTPT-------QWFFREGSMF------VALAASVFSLLAIAIERH
LTMLKMKLHNNGNT--WRVFLLISAVWMVAAVLGG-LPVMG-----------WNCIQK------------------MSRC
STVLPLY-----HKTYILFCTTV-FSIILMAIVVLYARIYT---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
LVRTRSRKLVFRKVSNG-------------------------------------------------------------RG
NAGAAVKSSEKSLALLKTVFIVLSCFIACWAPLFVLLLLD-TACQTLSCPILY--------------------KAEWFLA
LAVLNSAMNP-------------------------LIYTLTSNEMRRAFLKTLLC----CTACLRPK-------------
-----------ATFTSP----IMGAEFSRSRS-----------------------------DNSSHPTREDGEHSPRGRR
TASSGNVTLSS---------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Gasterosteus_aculeatus_S1PR1_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------SDEISSFIPVCRQKERDDAMAEPN--------YSDLIAKHYNYTGKYRKT
-------------------------------------QQD-AGLKADSVVFIIVCCFIILENILVLTTIWRTKKF-HKPM
YYFIGNLALSDLLAGVVYT----ANILLSGANTYKLTPT-------QWFIREGSMF------VALAASVFSLLAIAIERH
LTMLQMKLHNNGNT--CRVFLLISAVWMVAAVLGG-LPVMG-----------WNCIRS------------------VTSC
STVLPLY-----HKTYILFCTTV-FSIILMAIVVLYARIYA---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
LVRARSRRLVFRKPTNG-------------------------------------------------------------RG
SAGANMKSSEKSMALLKTVIIVLSCFIACWAPLFILLLLD-AGCETLSCPILY--------------------KAEWFLS
LAVLNSAMNP-------------------------LIYTLTSNEMRRAFLKTLLC----CTACLRPK-------------
-----------AKSSGP----IMGAEFSRS-S-----------------------------DK--YLKRSVLLPLPNNHR
SVK-----------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Oryzias_latipes_S1PR1_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------VVSVPIPYLRHIRLQTMAESS--------YSDLIAKHYNFTGKFRKT
-------------------------------------QQD-SGLKADSVIFIIVCCFIILENILVLATIWRTKKF-HKPM
YYFIGNLALSDLLAGVVYT----ANILLSGANTYKLTPT-------QWFLREGSMF------VALAASVFSLLAIAIERH
LTMLKMKLHNNGNT--CRVFLLISTVWMIAAMLGG-LPLMG-----------WNCIHR------------------MSEC
STVLPLY-----HKTYILFCTTV-FSIILMAIVVLYARIYT---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
LVRTRSSKLVFRKVTNS-------------------------------------------------------------RG
NPSANTKSSEKSLALLKTVIIVLSCFIACWAPLFILLLLD-VACETLSCPILY--------------------KVDWFLA
LAVLNSAMNP-------------------------LIYTLTSNEMRRAFLKTLLC----CTTCIRPK-------------
-----------AKFTGP----IMGAEFSRSKS-----------------------------DNSSHPHKEEGEYSPKETT
AVSSGNATSSS---------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Drosophila_melanogaster_S1PR1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------MSAFRYFS--ITDFSFEGPLLPLHAATTSKDAKDSD------------------
-------------------------------------SPSSELNIPYTVFEVLVAIVSIIGNVLVIIV-FRRERKLRRRT
NYYIVSLAMADLLVGALGI----PFAILASMGLPRNLHA--------CLFTVSLLV------VLCTISIFCLVAVSVDRY
WAILYPMAY-SRNVRTRTAIFIISMCWVAGTIVGF-LPLFG----------WHADVNH------------------NQEC
LFVEVMD-----YNYLVFLYFAT-IITPALLMLAFYTHIYRVIIKQVR--------------------------------
--------------------------------------------------------------------------------
-----------------------------------------QIVTMN-----------PASDLSRRSSAAVVQVTTPGRG
GHTGTMLRVLG---------------------------------------------------------------------
------AARKRDVKATQNLSIIVLFFMICWIPLYTINCIKAFCPDCYVHPK----------------------LTLFCII
LSHLNSAVNP-------------------------VLYAYHLKDFRAALKNLLLKMMGVDIDQQAEAIHRFSVAS-----
--------QHRLQSMDSNMRSTQPRLYVGEYSPIWLRQQQEALKNSQLLPKCGVVSPCFNNINQTVAAVASVTTDLEREM
WNIVEASSGAELGETSYEFPSPAPGSQRSSERNSSSTVPPAPPAPAKPSVPSASYDNHNYSFSQDEDEDDDDLEFEDVFV
PASSVPNPVQPGIDPVELRRSLALVMREKLRSDDTDSRPMGNNQDLPIDEQSRERPLSTQTSPTNGPLPALLRAKLLAGN
SNSAHCLPGSTASPAPQEQSGIFVIDSEASPGSNGHKPKYRKGTAFTRSSLKKSRSCNCSSIAKGRGVHDEPSSNLCRDQ
ESSVLPQHPQPANHPTENFFSPLRSVGSFMQHSNLFHFLQPHAARPTSSTASSTASTPTPSPPPMGQAQEESVPVGLTTS
SPSLLATSAES---------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Apis_mellifera_S1PR1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------MEFPSNISELANNLTVTALNASTHS-------------------------
-----------------------------------------ELNLPYTVCEILVAVCAVFGNGLVIIV-FSKEKKLRRRT
NYYIISLATADLLVGLFAI----PFAILASIGLPKNLHA--------CLFTVSVLI------VLCTISIFCLVAVSVDRY
WAILHPMGY-SRTVRTKTAIGIICVCWIAGTLVGF-LPLLG----------WNAGKKS------------------NEKC
IFTEVMD-----YDYLVFLYFAT-IIFPALLIAAFYAHIYRVVVKQLQ--------------------------------
--------------------------------------------------------------------------------
-----------------------------------------QIVTMN---------------PGRRTG-----------N
QTTGTMLRLLG---------------------------------------------------------------------
------AARKREVKATQNLSRIVIFFIICWIPLYTINCVMAFCPWCRVNDV----------------------VMNFCII
LSHLNSAGNP-------------------------LLYAYHLKDFRAALKNFMWNLLFPHNN------------------
-------------------MKSSVVSVIHERGSLVDSQRQYHRQIGGLSSSKRPTSSLLRQVTDVRSKGLSVSRDIS---
--------------------------IRDKETGNASSSSQS-----------------------DKQEDDNMSQNSNEFQ
RNES-----------------------DKFENNRIDSNISKSSSHITSMELQTYKPLMP---------------------
-----LLPAEIDNVEETPPASIFVIEVDVNHMESVHKKVNEELTENKDKG------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Homo_sapiens_S1PR2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------MGSLYSEYL--------NPNKVQEHYNYTKETLET
--------------------------------------QETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKF-HSAM
YLFLGNLAASDLLAGVAFV----ANTLLSGSVTLRLTPV-------QWFAREGSAF------ITLSASVFSLLAIAIERH
VAIAKVKLYGSDKS--CRMLLLIGASWLISLVLGG-LPILG-----------WNCLGH------------------LEAC
STVLPLY-----AKHYVLCVVTI-FSIILLAIVALYVRIYC---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
VVRSSHADMA----------------------------------------------------------------------
--APQT------LALLKTVTIVLGVFIVCWLPAFSILLLD-YACPVHSCPILY--------------------KAHYFFA
VSTLNSLLNP-------------------------VIYTWRSRDLRREVLRPLQCWRPGVGVQGRRR-------------
-------------GGTPG----HHLLPLRS-------------------------------SSSLERG---MHMPTSP-T
FLEGNTVV------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Pan_troglodytes_S1PR2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------MGSLYSEYL--------NPNKVQEHYNYTKETLET
--------------------------------------QETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKF-HSAM
YLFLGNLAASDLLAGVAFV----ANTLLSGSVTLRLTPV-------QWFAREGSAF------ITLSASVFSLLAIAIERH
VAIAKVKLYGSDKS--CRMLLLIGASWLISLVLGG-LPILG-----------WNCLGH------------------LEAC
STVLPLY-----AKHYVLCVVTI-FSIILLAIVALYVRIYC---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
VVRSSHADVA----------------------------------------------------------------------
--APQT------LALLKTVTIVLGVFIVCWLPAFSILLLD-YACPVHSCPILY--------------------KAHYFFA
FSTLNSLLNP-------------------------VIYTWRSRDLRREVLRPLQCCRPGVGVQGRRR-------------
-------------GGTPG----HHLLPLRS-------------------------------SSSLERG---MHMPTSP-T
FLEGNTVV------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Macaca_mulatta_S1PR2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------MGSLYSEYL--------NPNKVQEHYNYTKETLET
--------------------------------------QETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKF-HSAM
YLFLGNLAASDLLAGVAFV----ANTLLSGSVTLRLTPV-------QWFAREGSAF------ITLSASVFSLLAIAIERH
VAIAKVKLYGSDKS--CRMLLLIGASWLISLVLGG-LPILG-----------WNCLGH------------------LEAC
STVLPLY-----AKHYVLCVVTI-FSIILLAIVALYVRIYC---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
VVRSSHADVA----------------------------------------------------------------------
--GPQT------LALLKTVTIVLGVFIVCWLPAFSILLLD-YACPVHSCPILY--------------------KAHYFFA
FATLNSLLNP-------------------------VIYTWRSRDLRREVLRPLQCWRPGVGVQGRRR-------------
-------------DGTPG----HHLLPLRS-------------------------------SSSLERG---MHMPTSP-T
FLEGNTVV------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Mus_musculus_S1PR2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------MGGLYSEYL--------NPEKVLEHYNYTKETLDM
--------------------------------------QETTSRKVASAFIIILCCAIVVENLLVLIAVARNSKF-HSAM
YLFLGNLAASDLLAGVAFV----ANTLLSGHVTLSLTPV-------QWFAREGSAF------ITLSASVFSLLAIAIERQ
VALAKVKLYGSDKS--CRMLMLIGASWLISLILGG-LPILG-----------WNCLNQ------------------LEAC
STVLPLY-----AKHYVLCVVTI-FSVILLAIVALYVRIYF---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
VVRSSHADVA----------------------------------------------------------------------
--GPQT------LALLKTVTIVLGVFIICWLPAFSILLLD-STCPVRACPVLY--------------------KAHYFFA
FATLNSLLNP-------------------------VIYTWRSRDLRREVLRPLQCWRRGKGVTGRR--------------
-------------GGNPG----HRLLPLRS-------------------------------SSSLERG---MHMPTSP-T
FLEGNTVV------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Canis_familiaris_S1PR2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------MGNLYSEYL--------SPNKVREHYNYTKETLDT
--------------------------------------QETASRQAALVIIIILCFAIVVENLLVLIAVARNSKF-HSAM
YLFLGNLAASDMLTGVAFV----ANTLLSGPVTLGLTPI-------QWFAREGSAF------ITLSASVFSLLAIAIERH
VAIAKVKLYGSDKS--CRMLLLIGASWLISVALGG-LPILG-----------WNCLGH------------------LEAC
STVLPLY-----TKHYVLCVVTI-FSVILLAIVALYVRIYC---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
VVRSSQADVA----------------------------------------------------------------------
--GPQT------LALLKTVTIVLGVFIVCWLPAFSILLLD-YACPVRSCPILY--------------------KAHYFFA
FATLNSLLNP-------------------------VIYTWRSRDLRREAQR-----------FGKR--------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Felis_catus_S1PR2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------MGSLYSEYL--------SPSKVLEHYNYTKETLDT
--------------------------------------QETTSRWVALVIIVLICFTIVVENLMVLIAVARNSKF-HSAM
YLFLGNLAASDLLTGVAFV----ANTLLSGPVTLGLTPL-------EWFAREGSAF------ITLSASVFSLLAIAIERH
VAIAKVKLYGSDKS--CRMLLLIVASWLISLVLGG-LPILG-----------WNCLGH------------------LEAC
STVLPLY-----TKHYVLCVVTI-FSVILLAIVALYIRIYC---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
VVRSSHVDVT----------------------------------------------------------------------
--GPQT------LALLKTVTIVLGVFIVCWLPAFSILLLD-YACPVRSCPVLY--------------------KAHYFFA
FATLNSLLNP-------------------------VIYTWRSRDLRREVLRPLQCCRRAAGVQGRR--------------
-------------GGTPG----HRLLPLRS-------------------------------SSSLERG---THMPTSP-T
FLEGNTMV------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Pteropus_vampyrus_S1PR2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------MGSLYSEYL--------SPTKVQEHYNYTKETLDT
--------------------------------------QETPSRKVASALIIILCCAIVVENLLVLIAVARNSKF-HSAM
YLFLGNLAASDLLAGVAFI----ANTLLSGSVTLRLTPV-------QWFAREGSAF------ITLSASVFSLLAIAIERH
VAIAKVKLYGSDKS--CRMLLLIAASWLISLALGG-LPILG-----------WNCLGH------------------LEAC
STVLPLY-----AKHYVLCVVTI-FSAILLAIVVLYIRIYC---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
VVRSSHADVA----------------------------------------------------------------------
--GPQT------LALLKTVTIVLGVFIVCWLPAFSILLLD-YACPVHSCPILY--------------------KAHYFFA
FATLNSLLNP-------------------------VIYTWCSRDLRREVLRPLQCWRQAAGVQGRR--------------
-------------SGTPG----HHLLPLRS-------------------------------SSSLERG---THMPTSP-T
ILEGNTVV------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Danio_rerio_S1PR2_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------MTTCRLFAGFCQAVTMSKYSQYF--------NKTLIQVHYLTAKEMTAE
ELRD--------------------------------RIESKQSLSSLNILFVVICSIIILENLLVLIAVFRNKKF-HSAM
FFFIGNLAFSDLLAGSAYI----ANIFLSGPRTFHLTPV-------QWFIREGTAF------IALSASVFSLLAIAIERY
IAITKVKVYGSNKT--CRMFLLIGACWVMSILLGG-LPIIG-----------WNCINN------------------LDDC
SAVLPLN-----TRYYIRFVVTI-FSIILLSIVILYVRIYL---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
IVRTSHQEAT----------------------------------------------------------------------
--NSPA------YALLKTVTIVLGVFIICWLPAFTILLLD-TSCKMKQCPILN--------------------NAGIFFS
FATLNSALNP-------------------------LIYTLRSKDMRKEFLRVLCCWG-------LLNC------------
-------------GRPPH----RCMVPLKS-------------------------------SSSMEHCTNKHEHQSIP-I
MQDCTTCV------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Tetraodon_nigroviridis_S1PR2_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------MKSKYSQYY--------NKSLIQCYYIFAKNLTPQ
DLSK--------------------------------RNDNKNQLPTLNIVIVVLCTIIILENLLVLIAVCRNKKF-HSAM
FFFIGNLAFSDLLTGSAYI----ANIFLSGSRTFELMPI-------QWFIREGTAF------IALAASVFSLLAIAVERY
LAITKVKVYGATKT--CRMFLLIGASWVTSILLGG-LPILG-----------WNCINN------------------LPEC
SAVLPLY-----SKKYILFVVTI-FSIILLSIVILYVKIYL---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
IVRSSRQEAT----------------------------------------------------------------------
--NSAT------YSLLKTVTIVLGVFILFWLPAFTILLLD-SFCNIQFCSILS--------------------EAQMFFG
FATLNSALNP-------------------------VIYTLRSKDMRKEFLRVLCCWG-------VLQS------------
-------------GRPSD----RCLVPLKS-------------------------------SSSLEHCTHKHEHQTMP-I
MQDCTTCV------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Gasterosteus_aculeatus_S1PR2_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------LGSVRVPS--FTYSMKSKYSQYY--------NQSLIHSYYTFAKNMSTQ
ELAK--------------------------------RIENKKKLSSLDMVIVVLCTIIILENLLVLIAVCRNKKF-HSAM
FFFIGNLAFSDLLAGSAYI----ANIFLSGSRTFDLMPV-------QWFIREGTAF------IALAASVFSLLAIATERY
IAITKVKVYGSTKT--CRMFLLIGACWVTSILLGG-LPIMG-----------WNCIND------------------LPEC
SAVLPLY-----SKKYILFVVTI-FSLILLSIVILYVRIYL---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
IVRSSHQEAT----------------------------------------------------------------------
--NLPA------YALLKTVTIVLGVFIMCWLPAFTILLLD-TSCRIQFCPILS--------------------KAEFFFS
FATLNSALNP-------------------------VIYTLRSKDMRKEFLRVLCC-------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Oryzias_latipes_S1PR2_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------VGRTSYPPAVFCPFHKSKYSQYY--------NTNLIRLHYAHAKNMSKA
EIHE--------------------------------RESEKDHPDLLSIIILVICTIIIFENLLVLMAVWRNKKF-HSAM
FFFIGNLAFSDLLAGCAYI----VNIILSGPRTYSLCPV-------QWFIREGTAF------IALAASVFSLLAIAIERY
VAITKVKVYGSNKS--CRMFLLIGACWVTSILLGG-LPILG-----------WNCIFD------------------LGDC
STVLPLY-----SKKYIVFVVTV-FSLILLSILILYVRIYL---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
IVRSSNQVTT----------------------------------------------------------------------
--NMQA------YSLLKTVTIVLGVFIVCWLPAFTILLLD-SSCSIQVCTILD--------------------KAKIFFG
FATLNSALNP-------------------------VIYTLRSKDMRREFLRVLCC-------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Hydra_magnipapillata_S1PR2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------MIVVHIHKIINTSSEIKKEEESKG------------------------------
----------------------------------------------------------------------RNTSKLNVYS
-----VIAFCEIGCDYN---------------IINRNAV---------YFFITTDV------LFGITSILSLTAISLERM
FAVKFPTRH--FNLSSALVFIVIAFTWFIGIVFSV-AQFFI---------------------------------------
--SFQNV-----RWYIAFLLVFA-YIFPLFIIVVSYCIIYCAIR-MMR--------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----DNSNQD----------------------------------------------------------------------
------GKTKQELRVAKIISIIIGLFFICWSPFFILNTVHLFCKEVYCRKLPIW-------------------LINITKM
LHYSHSMMNF-------------------------FVYGYRSPDFRHIFR-AFLKCRLSLMQGRVRSLSESINLE-----
--------QSSS-----FKRERNIENSEEVLVT---LASDEI--------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Homo_sapiens_S1PR3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------MATALPPRLQPVRGN------------ETLREHYQYVGKLAGR
LK-----------------------------------EASEG-STLTTVLFLVICSFIVLENLMVLIAIWKNNKF-HNRM
YFFIGNLALCDLLAGIAYK----VNILMSGKKTFSLSPT-------VWFLREGSMF------VALGASTCSLLAIAIERH
LTMIKMRPYDANKR--HRVFLLIGMCWLIAFTLGA-LPILG-----------WNCLHN------------------LPDC
STILPLY-----SKKYIAFCISI-FTAILVTIVILYARIYF---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
LVKSSSRKVA----------------------------------------------------------------------
----NHNNSERSMALLRTVVIVVSVFIACWSPLFILFLID-VACRVQACPILF--------------------KAQWFIV
LAVLNSAMNP-------------------------VIYTLASKEMRRAFFRLVCN----CLVRGRGA-------------
-------------RASP---IQPALDPSRSK-----------------------------SSSSNNSS-HSPKVKEDLPH
TAPSSCIMDKNA-ALQNGIFCN----------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Pan_troglodytes_S1PR3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------MATALPPRLQPVRGN------------ETLREHYQYVGKLAGR
LK-----------------------------------EASEG-STLTTVLFLVICSFIVLENLMVLIAIWKNNKF-HNRM
YFFIGNLALCDLLAGIAYK----VNILMSGKKTFSLSPT-------VWFLREGSMF------VALGASTCSLLAIAIERH
LTMIKMRPYDANKR--HRVFLLIGMCWLIAFTLGA-LPILG-----------WNCLHN------------------LPDC
STILPLY-----SKKYIAFCISI-FTAILVTIVILYARIYF---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
LVKSSSRKVA----------------------------------------------------------------------
----NHNNSERSMALLRTVVIVVSVFIACWSPLFILFLID-VACRVQACPVLF--------------------KAQWFIV
LAVLNSAMNP-------------------------VIYTLASKEMRRAFFRLVCN----CLVRGRGA-------------
-------------RASP---IQPALDPSRSK-----------------------------SSSSNNSS-HSPKVKEDLPH
TAPSSCIMDKNA-ALQNGIFCN----------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Macaca_mulatta_S1PR3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------XREHYQYVGKLAGR
LM-----------------------------------EASEA-GTLTTVLFLVICSFIVLENLMVLIAIWKNNKF-HNRM
YFFIGNLALCDLLAGIAYK----VNILMSGKKTFSLSPT-------VWFLREGSMF------VALGASTCSLLAIAIERH
LTMIKMRPYDANKK--HRVFLLIGMCWLIAFTLGA-LPILG-----------WNCLHN------------------LPDC
STILPLY-----SKKYIAFCISI-FTAILVTIVILYARIYF---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
LVKSSSRKVA----------------------------------------------------------------------
----NHNNSERSMALLRTVVIVVSVFIACWSPLFILFLID-VACRVQACPVLF--------------------KAQWFIV
LAVLNSAMNP-------------------------VIYTLASKEMRRAFFRLVCN----CLVRGRGA-------------
-------------RASP---IQPALDPSRSK-----------------------------SSSSNNST-HSPKVKEDLPH
TAPSSCIMDKNA-ALQNGIFCK----------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Mus_musculus_S1PR3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------MATTHAQGHQPVLGN------------DTLREHYDYVGKLAGR
LR-----------------------------------DPPEGGTLITTILFLVTCSFIVLENLMVLIAIWKNNKF-HNRM
YFFIGNLALCDLLAGIAYK----VNILMSGRKTFSLSPT-------VWFLREGSMF------VALGASTCSLLAIAIERH
LTMIKMRPYDANKK--HRVFLLIGMCWLIAFSLGA-LPILG-----------WNCLEN------------------FPDC
STILPLY-----SKKYIAFLISI-FTAILVTIVILYARIYC---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
LVKSSSRRVA----------------------------------------------------------------------
----NHN-SERSMALLRTVVIVVSVFIACWSPLFILFLID-VACRAKECSILF--------------------KSQWFIM
LAVLNSAMNP-------------------------VIYTLASKEMRRAFFRLVCG----CLVKGKGT-------------
-------------QASP---MQPALDPSRSK-----------------------------SSSSNNSS-HSPKVKEDLPR
VATSSCIIDKNR-SFQNGVLCK----------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Canis_familiaris_S1PR3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------MCLRRPLLGSGAEPLRARAMATVVPPRARPSPGNGN--------ETETLHEHYNYVGKLEGR
LR-----------------------------------EAPEG-SMPTTVLFLIICSFIVLENLMVLIAIWKNNKF-HNRM
YFFIGNLALCDLLAGIAYK----VNILMSGKRTLSLSPT-------LWFLREGSMF------VALGASTCSLLAIAIERH
LTMIKMRPYDANKK--HRVFLLIGMCWLIAFSLGA-LPILG-----------WNCLHN------------------LPDC
STILPLY-----SKRYIAFCISI-FTAILVTIVILYARIYF---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
LVKSSSRRVA----------------------------------------------------------------------
----SPHNSERSMALLRTVVIVVSVFIACWSPLFILFLVD-VACRVKQCAILF--------------------KAQWFIV
LAVMNSAMNP-------------------------VIYTLASKEMRRAFFRLVCT----CLVRRWGA-------------
-------------RSSP---TQPALDPSRSK-----------------------------SSGSNNSS-PSPKSKEDPPQ
IAASPCIMDGNK-TLQNGILCK----------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Felis_catus_S1PR3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------QHYNYVGKLEGR
LK-----------------------------------EAPEG-STLTTVLFLVICSFIVLENLMVLIAIWRNNKF-HNRM
YFFIGNLALCDLLAGIAYK----VNILMSGKRTLSLSPT-------VWFLREGSMF------VALGASTCSLLAIAIERH
LTMIKMRPYDANKK--HRVFLLIGMCWLIALSLGA-LPILG-----------WNCVHD------------------LPDC
STILPLY-----SKKYIAFCISI-FTAILVTIVILYARIYF---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
LVKSSSRRVA----------------------------------------------------------------------
----SPHNSERSMALLRTVVIVVSVFIACWSPLFILFLVD-VACRVKECAVLF--------------------KAQWFIM
LAVLNSAMNP-------------------------VIYTLASKEMRRAFFRLVCT----CLVRGRGA-------------
-------------RSSP---TQPALDPSRSK-----------------------------SSGSNNSS-PSPKSKEDPPQ
RVASPCITDGNK--------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Myotis_lucifugus_S1PR3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------LYEHYNYVGKLAGR
LT-----------------------------------DAPEG-SALTTVLFLVICSFIVLENLMVLIAIWKNKKL-HNRM
YFFISNLALCDLLAGIAYK----VNILMSGKRTLSLSPT-------VWFLREGSMF------VALGASTCSLLAIAIERH
LTMIKMRPYNANKK--HRVFLLIGMCWLIALSLGA-LPILG-----------WNCLQN------------------LPDC
STILPLY-----SKKYIAFCISI-FTAILVAIVILYARIYC---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
LVKSSSRRVA----------------------------------------------------------------------
----NPQHSERSMALLRTVVIVVSVFIACWSPLFILFLVD-VACKVKECAVLF--------------------KDKWFIV
LAVLNSAMNP-------------------------VIYTLASKEMRRAFFRLVCN----CLVRAQGT-------------
-------------RSLP---IQLTLDPSKSK-----------------------------SSGS-NSS-PSPKSKEDITQ
TAPSPCITDRNK--------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------
>Xenopus_tropicalis_S1PR3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------NMASGSLPSKKLEP----RR--------CDEVINRHYNYTGKLKER
-------------------------------------E--LDHMDMTEIVFLIICSLIVLENLMVLIAIWKNNRF-HNRM
YFFIGNLALCDMLAGIAYI----VNICMSGSKTMDISLT-------AWFVREGSMF------IALGASTFSLLAIAIERH
LTMIKMRPYDANKK--YRVFLLIGTCWLISFSLGA-LPILG-----------WNCIED------------------LPNC
STILPLY-----SKRYVGFCISI-FIAILIAIVILYARIYI---------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
LVKSSSRRVT----------------------------------------------------------------------
----NHSNSERSMALLRTVVIVVGVFIACWSPLFILLLID-VACEVKTCSILY--------------------KAQWFIA
LAVLNSALNP-------------------------VIYTLASKEMRRAFFRLVCS----CLVKTNNS-------------
-------------RSLP---IQPTPDQSRSK----------------------------