>HUMAN_OSBPL3
--------------------------------------------------------------------------------
---------------------------------------------------MMSDEK--NLGVSQKLVSPSRST-SSCSS
KQGSRQ-------------------------------------------------------DSWEVVEGLRGEM-NYTQE
PPVQKGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKS
EEVFDEWVSKLRHHRMYRQNEIAMFPHEVN-----------------HFFSGS----TITDSSSGVFDSISSRKRSSISK
QNLFQTG----SNVSFSCGG-ETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQS----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------MDVLHRTYS------------APA-INAIQGGSFESPK-KEKRSHRRWRSRAI
GKDAKGTLQ-------------------------VPKPFSG-PVRLHSSNPNLSTLDFGEEKNYSDGS---ETSSEFSKM
QEDLCHIAHKVYFTLRSAFNIMSAEREKLKQLM-EQDASSSPSAQVIGLKNALSS-------------------ALAQNT
DLKERLRRIHAESLLLDSPAVAKSGDNLAEENSRDE-NRALVHQLSNESRLSIT--DSLSEFFDAQEVLLS-----PSSS
ENEISDDD------------SYVSD-----ISDNLSLDNLSNDLDNERQTLGPVLDS--GREAK---------------S
RRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLN-TLQRLCEELEYSELLDKAAQ-IPSPLERMVYVAAF
AISAYASSYYRAGSKPFNPVLGETYECIR--EDKGFQFFSEQVS-HHPPISACHAESRNFVFWQDVRWK--NKFWGKSME
IVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYG-EIVIKNLHDDSCYCKVNFIKAKYWSTNAH-EIEGTVFD
RSGKAVHRLFGKWHESIYCGGGSSSA------------------------CVWRANPMPKGYEQYYS-------------
FTQFALELNEMDPSSKSLLPPTDTRFRPDQR--FLEEGNLEEA---EIQKQRIEQLQRER--------------------
-----------------------RRVLEE----------NHVEHQPRFFRKSDD-------DSWVSNGTYLELR------
-----------------KDLGFSKLDHPV--LW-------------------------------
>MOUSE_OSBPL3
--------------------------------------------------------------------------------
----------------------------------------------------MSDEK--NLGVSQKLVSPSRST-SSCSS
KQGSRQ-------------------------------------------------------DSWEVVEGLRGEM-TYTQE
PPVQKGFLLKKRKWPLKGWHKRFFCLEKGILKYAKSQADIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKS
EELFDEWVSKLRHHRMYRQNEIAMFPRDVN-----------------HFFSGS----SVTDSAPGVFESVSSRKRSSLSK
QNSFPPG----SNLSFSCGG-DTRVPFWLQSSEDMEKCSKDMAHCHAYLLEMSQLLES----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------MDVLHRTYS------------APA-INAIQ-----------------------
----------------------------------VPKPFSG-PVRLHSSNPNLSTLDFGEEKSYSDGS---EASSEFSKM
QEDLCHVAHKVYFALRSAFNSISVEREKLKQLM-ELDTSPSPSAQVVGLKHALSS-------------------ALAQNT
DLKERLRRIHAESLLLDPPAVPKPGDNLAEENSRDE-GRALVHQLSNESRLSIT--DSLSEFFDAQEVLLS-----PSSS
ENEISDDD------------SYVSD-----ISDNLSLDNLSNDLDNERQTLGPVLES--SGEAR---------------S
KRRTSLPAPGPNTSSVSLWSILRNNIGKDLSKVAMPVELNEPLN-TLQRLCEELEYSELLDKASR-IPSPLERMVYVAAF
AISAYASSYFRAGSKPFNPVLGETYECIR--QDKGFQFFAEQVS-HHPPISACHAESGNFVFWQDVRWK--NKFWGKSME
IVPIGTTHVTLPAFGDHFEWNKVTSCIHNILSGQRWIEHYG-EIDIKNLNDDSCHCKVNFIKAKYWSTNAH-EIEGTVFD
RSGKAVHRLFGKWHESIYCGGASSST------------------------CVWRANPMPKGYEQYYG-------------
FTQFALELNEMDPLSRSLLPPTDTRFRPDQR--LLEEGDIEEA---EVQKQRIEKLQRER--------------------
-----------------------RRVLEE----------NGVEHQPRFFRKSSD-------DAWVSNGTYLELR------
-----------------KDLGFSKLDHPV--LW-------------------------------
>RAT_OSBPL3
--------------------------------------------------------------------------------
----------------------------------------------------MSDEK--NLGVSQKLVSPSRST-SSCSS
KQGSRQ-------------------------------------------------------DSWEVVEGLRGEM-TYTQE
PPAQKGFLLKKRKWPLKGWHKRFFCLEKGILKYAKSQTDIEREKLHGSIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKS
EDVFDEWVSKLRHHRMYRQNEIAMFPRDVN-----------------HFFPGS----SVTDSAPGVFESVSSRKRSSLSK
QNSFPAG----SNLSFSCGG-DTRVPFWLQSSEDMEKCSKDLAHCHTYLLEMSQLLES----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------MDVLHRTYS------------APA-INAIQGGAFESPK-KEKRSHRRWRSRAI
GKDAKGMLQ-------------------------VPKPFSG-PVRLHSSNPNLSTLDFGEEKSYSDGS---EASSEFSKM
QEDLCHVAHKVYFALRSAFNSISMEREKLKQLM-ELDTSSSPSAQVVGLKHALSS-------------------ALAQNT
DLKERLRRIHAESLLLDPPAGPKPGDNLAEEISRDE-SRALVHQLSNESRLSIT--DSLSEFFDAQEVLLS-----PSSS
ENEISDDD------------SYVSD-----ISDNLSLDNLSNDLDNERQTLGPVLES--SGEAR---------------S
KRRTSLPAPGPNTSSVSVWSILRNNIGKDLSKVAMPVELNEPLN-TLQRLCEELEYSELLDKAAH-MPSPLERMVYVAAF
AISAYASSYFRAGSKPFNPVLGETYECIR--QDKGFQFFAEQVS-HHPPISACHAESRNFVFWQDVRWK--NKFWGKSME
IVPIGTTHVTLPAFGDHFEWNKVTSCIHNILSGQRWIEHYG-EIVIKNLRDDSCHCKVNFIKAKYWSTNAH-EIEGTVFD
RSGKAVHRLFGKWHESIYCGGASSST------------------------CVWRANPMPKGYEQYYG-------------
FTQFALELNEMDPLSRSLLPPTDTRFRPDQR--LLEEGNIEEA---EVQKQRIEKLQRER--------------------
-----------------------RRVLEE----------NGVEHQPRFFRKSSD-------DAWVSNGTYLELR------
-----------------KDLGFSKLDHPV--LW-------------------------------
>COW_OSBPL3
--------------------------------------------------------------------------------
----------------------------------------------------MSDEK--SLAVSQKLVSPSRST-SSCSS
KQGSRQ-------------------------------------------------------DSWEVVEGLRGEM-NYTQE
PPIQKGFLLKKRKWPLKGWHKRFFYLDRGILKYAKNQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKS
EDVFDEWVSKLRHHRMYRQNEIAMFPHEVN-----------------HFFPGS----TVPDSGPGVMDTISSRKRSSISK
QNSFQTG----SNLSFSCGG-ETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQN----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------MDILHRTYS------------APA-INAIQGGAFESPK-KEKRSHRRWRSRAL
GKDAKGTLQ-------------------------VPKPFSG-PIRLHSSNPNLSTLDFGEEKNYSDGS---ETSSEFSKM
QEDLCHIAHKVYFTLRSAFNTISTEREKLKQLM-EQDVSASPSAQVLGLKHALSS-------------------ALAQNT
DLKERLCRIHAESLLLDLPAAAKSGDGLAEENSRDD-SRALVHQLSNESRLSIT--DSLSEFFDAQEVLLS-----PSSS
ENEISEDD------------SYVSD-----ISDNFSLDNLSNDLDNERQTLGPVIDS--GGEAR---------------S
KRRTCLPAPCPKSSNISLWNILRNNIGKDLSKVAMPVELNEPLN-TLQRLCEELEYSELLDKAAQ-LPNALERMVYVAAF
AVSAYASSYFRAGSKPFNPVLGETYECIR--EDKGFRFFSEQVS-HHPPISACHAESANFVFWQDVRWK--NKFWGKSME
IVPIGTTHVTLPAFGDHFEWNKVTSCIHNILSGQRWIEHYG-EIVIKNLNDDSCHCKVNFIKAKYWSTNAH-EIEGTVFD
QSGKAVHRLFGKWHESIYCGGSSSSA------------------------CIWRANPMPKGYEQYYG-------------
FTQFALELNEMDPLLKSLLPPTDTRFRPDQR--FLEEGNLEEA---EIQKQRIEQLQRER--------------------
-----------------------RRVLEE----------NKVEHQPRFFRCVNGGVLRVI-VGRVLDVAGKNVR------
-----------------KGGNCSAVAVLE--LFQLEAGRDDREEEYGDLDVSIDTKESPKY---
>HORSE_OSBPL3
--------------------------------------------------------------------------------
---------------------------------------------------MMSDEK--NLGVSQKLVSPSRST-SSCSS
KQGSRQ-------------------------------------------------------DSWEVVEGLRGEM-NYTQE
PPVQKGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKS
EEVFDEWVSKLRHHRIFRQNEIAMFPHEVN-----------------HFFPGS----AGTDSPSGALDSISSRKRSSISK
QSSFQTG----SNLSFSCG--ETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMNQLLQS----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------MDVLHRTYS------------APA-INAIQGGAFESPK-KEKRSHRRWRSRAI
GKDAKGTLQ-------------------------VPKPFSG-PVRLHSSNPNLSTLDFGEEKNYSDGS---ETSSEFSKM
QEDLCHIAHKVYFTLRSAFTIMSAEREKLKQLM-EQDASCTPSAQVIGLKHALSS-------------------ALAQNT
DLKERLCRIHAESLLLDPPAAAKSGDTLAEENSRDD-NRALVHQLSNESRLSIT--DSLSEFFDAQEVLLS-----PSSS
ENEISEDD------------SYVSD-----ISDNLSLDNLSNDLDNERQTLGPVLES--GGEAK---------------S
KRRTCLPAPGHNSSNISLWNILRNNIGKDLSKVAMPVELNEPLN-TLQRLCEELEYSELLDQAAR-VPSALERMVYVAAF
AVSAYASSYFRAGSKPFNPVLGETYECIR--EDKGFQYFSEQVS-HHPPISACHAESRNFVFWQDVRWK--NKFWGKSME
IVPIGTTHVTLPAFGDHFEWNKVTSCIHNILSGQRWIEHYG-EIVIKNLSDDSCHCKVNFIKAKYWSTNAH-EIEGTVFD
KNGKAVHRLFGKWHESIYCGGASSST------------------------CVWRANPMPKGHEQYYG-------------
FTQFALELNEMDPLLKSLLPPTDTRFRPDQR--FLEEGNLEEA---ERQKQRIEQLQRER--------------------
-----------------------RRVLEE----------NNVEHQPRFFRKSDD-------DSWVSNGTYLELR------
-----------------KDLGFSKLDHPV--LW-------------------------------
>OPOSSUM_OSBPL3
--------------------------------------------------------------------------------
----------------------------------------------------MSDEK--GLGLSQKLVSPSRST-SSCSS
KQGSRQ-------------------------------------------------------DSWEVVEGLRGEM-TCTQE
PQIQKGFLLKKRKWPLKGWHKRFFFLEKGILKYAKNLADIEREKLHGSIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKS
EEVFEEWVAKLRHHRVYRQNEIAMFPRDVN-----------------HFFPGS----TVTDSASGVFDSVSSRKRSSISK
QSSLQTG----SSLSFSCG--EARVPIWPHSSEDMEKCSKDLAHCHTYLIEMSQLLQS----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------MEVLHRTYS------------APA-INALQGGAFESPK-KEKRPHRRWRARAI
SKEAKGMLQ-------------------------VPKPYSG-PVRLHASNPNLSTLDFGEDKNYSDGS---ETSSEFSKM
QEDLCHIAHKVYFTLKSAFNTLSNEREKLRQIS-DHDYSSSPSAQIVGLKHALSS-------------------ALAQNT
DLKERLRRIHAESLFLDSAAGAKSSDGLAEEISGEE-GRALVHQLSNESRLSIT--DSLSEFFDAQEVLLS-----PSSS
ENEVSDDD------------SYVSD-----VSDNASVDNLSNDLDSERQTLGPILESDPGGQTRG-------------QT
QRRTSLPAPCPNTSNISLWNILRNNIGKDLSKVAMPVELNEPLN-ALQRLCEELEYSELLDQASR-TPDPLERMVYVAAF
AVSAYASSYFRAGSKPFNPVLGETYECIH--EEKGFQYFSEQVS-HHPPISACHAESANFVFWQDVRWK--NKFWGKSME
IVPVGTTHVTLPAFGDHFEWNKVTSCIHNILSGQRWIEHYG-EIIIKNLNEDSCHCKVNFIKAKYWSTNSH-EIEGTVFD
KAGKAVRRLFGKWHESIYSGTRSSST------------------------CIWRAHPMPKGHEQYYG-------------
FTQFALELNELDSLTRPFLPPTDTRFRPDQR--LLEEGNLEEA---ETQKQRVEQLQRER--------------------
-----------------------RRVMEE----------NNLEHQPRFFRKSSD-------DSWVSNGTYLDLR------
-----------------RDPGFSKLDNPT--LW-------------------------------
>PLATYPUS_OSBPL3
-----------------------------------------------------------------------MLVDLVSIK
IKAGINFPQPQKASLHLLPNPVEKDVNQTPPAKRQAVSIRLWLKVRCGFLALKSQDRGLSLVLDEKLQQPQHLA-QGACT
DKHS---------------------------------------------------------DSWEVVEGLRGSM-NYTQE
PPEQKGYLLKKRKWPLKGWHKRFFFLDKGILKYAKSQADVEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKS
EDVFDEWVAKLRHHRVYRQNEIAMFPRDVN-----------------HFFPGS----TVTDSAPGMFDSVSSRKGSSLSK
QNSVQTG----SGFSFACTSGETRIPLWLQSSEDMDKCSKDLTHCQAYLQEMSQLLQS----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------MEVLHRTYS------------APA-INVIQGGAFESPK-KEKRSQRKWRSRAI
GKDAKGTLQ-------------------------VPPVYPG-LVRLHASNPNLSTLDFGEEKNYSDGC---ETSTEFSKM
QEDLCHIAHKVYFTLSSAFNTISSEREKLKQML-EREASSSPSAQIVGLKHALSS-------------------AVAQNT
DLRDRLRRIHAESVLLDSATFAQSSDILAEENSREG-NRVLVHQLSNESKLSIS--DSLSEFFDAQEVLLS-----PSSS
ENEISDDD------------SYASD-----LSDNISEDNLSNDLDNERQTLGPVVES--VGGSQ---------------S
KRRTCLPAPCPNTSNISLWNILRNNIGKDLSKVAMPVELNEPLN-TLQRLCEELEYSELLDKAVL-LDNPLERMVYVAAF
AISAYASSYFRAGSKPFNPVLGETYECIR--EDKGFQFFSEQVS-HHPPISACHAESKNFVFWQDVRWK--NKFWGKSME
IVPIGTTHVTLPSFGDHFEWNKVTSCIHNILSGQRWIEHYG-EIIIKNQNDESCHCKVNFIKAKYWNPNAH-EIEGTVFD
KNGKAVHRLFGKWHESIYCGTPSSAT------------------------CIWRANPMPKGYEQCYG-------------
FTQFALELNEMDPSIRALLPPTDTRFRPDQR--FLEEGDIEGA---EFQKQRIEQLQRER--------------------
-----------------------RRVLED----------NNMEHQPRFFRKSED-------ESWVSNGTYLDLR------
-----------------KDLGFSKLDNPI--LW-------------------------------
>CHICKEN_OSBPL3
--------------------------------------------------------------------------------
----------------------------------------------------MSEEK--NFGASQKMLSPSRST-SSCSS
KQGSRQ-------------------------------------------------------DSWEIVEGLRGAM-NCTQE
PQKQEGCLLKKRKWPLKGWHKRYFFLDRGILKYSKCQADIERGKLHGCIDVGLSVMSVKKSTKCIDLDTEEQIYHLKVKS
QELFDEWVAKLRHHRMYRQNEISMFPHDVNN----------------LFFPVS----TTVDSGPGLCDLTPSRKAGSLTK
QNSLSAG----GNLSFSFSSNESRIPSWLQSSEDMEKCSRDLSTCHAYLLEMNQLLQS----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------MDVLHRTCS------------APA-INAMQVGPFESPK-KEKRAHRRWRSRVV
GKEAKGTLQ-------------------------VPSVFSA-PMRLHASNPNLSTIDFVEEKNYSDGS---ETSSEFTKM
QEDLVHIAHKVYFTLKSAFSSISTEREKLKQML-EHEASSSPSAQIVGLKNALTS-------------------AIAQNT
DLKDRLRRIHAESMILDSASNAKSSPDLVKENSREE-NRGLVHQISNESRLSIA--DSLTEFFDAQEVLLS-----ASSS
ENEVSDDD------------SYVSD-----ISDNVSEDNLSNDIENERQTLDCISES--GIGCH---------------S
KRRTCLPAPCPNTSNISLWNILRNNIGKDLSKVAMPVELNEPLN-TLQRLCEELEYSELLDKAAH-TPNPFERMVYIAAF
AVSAYASSYYRAGSKPFNPVLGETYECIR--EDKGFQFFAEQVS-HHPPISACHAESVNFAFWQDVRWK--NKFWGKSME
IVPVGTTHVTLPAFRDHFAWNKVTSCIHNILSGQRWIEHYG-EIIIKNLNDDTCYCKLTFIKAKYWNPNAH-EIEGSVMD
KTGNVVHRLFGKWHESLYCGTTSSSK------------------------CIWRANPMPKDYEQWYG-------------
FTQFALELNELDLQTRSLLPSTDTRFRPDQR--FLEEGNIEAA---EMQKQRIEQLQRER--------------------
-----------------------RKVLEE----------NNLEHQPRFFRKSKD-------DSWVSNGTYMDLR------
-----------------REPGFSKLDNPV--LW-------------------------------
>ANOLE_LIZARD_OSBPL3
--------------------------------------------------------------------------------
---------------------------------------------------IMTEEK--NLGVSQKVLSPSRST-SSSSS
KQGSRQ-------------------------------------------------------DSWEIVEGLRGAM-NYTQE
PQKQEGYLLKKRKWPLKGWHKRCFFLDRGILKYAKSPADIERGKLHGCIDVGLSVMSVKKSTKCIDLDTEEHIYHLKAKS
QEVFDEWVRQLRHHRMYRQNEISMFPHDINN----------------HFFPASS---SITDSVTGFLESPTSRKRGTLTQ
QNSVQTG----SSLSFSCSANESRIPPWLHSSEEMERCSKELSHCHSYLLEMSQLLQS----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------MEVLHRTYS------------APA-INAMQGIPFESPK-KEKRSHRRWRSRAL
GKDTKAMLQ-------------------------VPSVLSA-PLRLHASNPNLSTLDFAEEKIYSNGS---ETTSEFSKM
QEDLCHIAHKVYFTLKSAFSTISTEREKLKQMF-DHDAVSSPSAQIVGLKNALSS-------------------AIAQNT
DLKDRLRRIHAESMLLDSAANAKSNPDLAKENSEDE-SRGLVHQLSNESRLSIT--DSVTEFFDAQEVLLS-----ASSS
ENEVSDDD------------SYASD-----ISDNISEDNLSNDIENERQPLDCVPDG--RVESH---------------S
KRRTCLPAPCPNTSNISLWNILRNNIGKDLSKVAMPVELNEPLN-TLQRLCEELEYSELLDKAAH-TPDMFERMVYVAAF
AVSAYASSYYRAGSKPFNPVLGETYECVR--EDKGLQYFSEQV-------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------
>ZEBRAFISH_OSBPL3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------MKGWHKRYFYLDKGILKYAKCAADVEKGKLHGCIDVGLSVMAIKKKAKCIDLDTEENIYHLKIKS
QELFDEWVSKLRHHRLYRQNEIAMFPHEKA-----------------LFHPHYP--LTSSPT--------IPD---SQAI
RKRPS----------------DLLVTAWLQSSDDMDRCTKELSVCEAQLLELNHLLRS----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------MEVLHRTYS------------APA-INALQASTYDSPK-KEKRHPRKWRPKNY
GKDNKTTLQ-------------------------VPSCISAGSVRLHASNPNLSSVDLTTEKTYHEPL---DSPIDVSKL
QEDFCRVANNLHTTMKSALCMLTTEKERVKQML-DYILDQ----------------------------------------
-------------------------------DSSDC-SRPLVHQASNESRASIS--ESLSEFFDAQEVLLS-----ASSS
ENEASEDD------------SYISD-----ISDNVSMDNFSNEAENERLNT-----GGNDAFLQ----------------
-RRSCLPSPSPNTSNISLWNILKNNIGKDLSKVAMPVELNEPLN-TLQRLCEELEYSELLDKAAH-TQDPFERMVYIATF
AVSGYASSYYRAGGKPFNPVLGETYECDR--PDKGFRFVAEQVS-HHPPISSCHAESKNFIFWQDVRWR--NKFWGKSME
IVPVGSSHVVLPGFGDHYEWNKVTSCIHNILSGQRWIEHYG-EISIKNSNSEKCQCKVTFIKAKYWNSSMN-EVEGSVTD
HKGKVVHKLFGKWHEGMYCGSPPSAT------------------------CIWRTNPMPPEFEQYYG-------------
FTKFAMELNELDPLTKPLLPPTDTRLRPDQR--LLEEGNVQSA---EVQKQRIEQLQRER--------------------
-----------------------RKVLEE----------NHMTHQPRFFQKSKD-------ETWVSNNTYWDLR------
-----------------KDPGFSNLDCPV--LW-------------------------------
>FUGU_OSBPL3
--------------------------------------------------------------------------------
---------------------------------------------------------------KMTSPSPTHSDNSSSSS
KHDGNQ-------------------------------------------------------DSWEIIEGLRGVS-ANIQE
PDRQEGFLLKRRKWPMKGWHKRYFLLEKGILKYAKRAADLKKGKLHGCIDVGLSVMSIKKKAMCIDLDTEDNIFHLKVKS
QELFEEWVSKLRHHRVFRQNEIATYPHERH-----------------LFYPHTS--PSLNES--------MKK-RSTLTK
QTSIH----------------QSKLSSWLHSSMDMDKCCKDLEECESYLLELNLLLKS----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------MEVLHRTYS------------APA-ISGLQASTYELPK-KEKRQ-RKWRSKNN
GKETKSTLQ-------------------------VPSCISSQSPRFHASNPNLSTTDSNAQELCPESP---DSPTEVSRL
QQDFCRLANNIHGRLKSTLSTMLAEQDRLRQTI-EVQAPQP--AQVMGLKTAYAS-------------------PLSVNL
FP---------------------------YQECSGG-SHSLVHQASSESKASIP--ESISEFFDAQEYLLS-----SSSS
ENEVSDDD------------SYISD-----VSDSISMDTCSNEGNSERQNS----VSGAVTLVR----------------
-RRSTLPSPRPSSS-VSLWNILRNNIGKDLSKVAMPVQLNEPIN-TLQRLCEELEYSELLDTANQ-TQDPYQRMVYVATF
AVSAYASTHHRAGSKPFNPVLGETYECDR--PDKGFRFIAEQVK-HHPPVSACHSDSQNFTFWQDVRWK--NKFWGKSME
IVQMGTTHVTLPAFGDHYEWNKVTSCIHNILSGQRWIEHYG-EMAIKNINSDNCQCKITFVKANSWSSSVN-EIEGVVTD
SKGKVVHSIFGKWHESVFQGDPPTAM------------------------CIWRANPMPSDQEQYYG-------------
FTQFAMELNELEPSLRLRLPPTDTRFRPDQR--FLEEGNVDGA---EEQKQRIEQLQRER--------------------
-----------------------RKVLQD----------NNMTHKPRFFKKSNN-------DTWVSNNTYWDLR------
-----------------REPGFSKIDFPV--LW-------------------------------
>MEDAKA_OSBPL3
--------------------------------------------------------------------------------
----------------------------------------------------SSSTRHLSENRKMTTPSPTHSD-SSDSS
KHESNR-------------------------------------------------------DSWEIVEGLRGVP-ASMQE
PDRQEGFLLKRRKWPMKGWHKRYFVLVKGIMTYGKRGTDIQKGKIHGCIDVGLSVMSIKKKAMCIDLDTEDNIYHLKVKS
SELFEEWVSKLRHHRLFRQNEIAVYPHERH-----------------LFHPHASSSPTFNDS--------YRR--STLTK
QASVH----------------QAKVSSWLHSSEDMNKCSKELEECESYLLELNLLLKS----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------MEVMHRTYS------------APA-ITSLQASAYDNPK-KEKRP-KRWRSKNN
GKETKATLQ-------------------------VPSCISSQSPRLHASNPNLSTTSS--QEVCSESP---DSPTDVSRL
QEDFCRLANNIHTTLKSAHSSLTAERDRLKHTI-DLQGPQP--AQVVGLKGVFSS-------------------VSSRAH
QKVIHCVFD---------------------QESPGT-PQSLVHQISNESKTSIP--ESISEFFDAQEYLLS-----SSSS
ENEVSDDD------------SYVSD-----VSDSVSMDTFD--GRSERQNSGTGILSSVVTVAR----------------
-RRSTLPSTCPSSS-VSLWNILRNNIGKDLSKVAMPVQLNEPLN-TLQRLCEELEYSNLLDIANQ-THDPYQRMVFVATF
AISAYTSTYCRAGSKPFNPVLAETYECDR--PEKGFRFIAEQVS-HHPPVSACHADSKNFKFWQDVRWK--NKFWGKSME
IVPIGTTHVTLPAFGDHYEWNKVTSCIHNILSGQRWIEHYG-EMSIKNVNGDVCQCKITFIKAKSWSSTVN-EIKGVVTN
AEGKTVHSIFGKWHESVFQGDPPSAT------------------------CIWRAKPMPKDQEQYYG-------------
FTQFAVELNELDSNLRPLLPPTDTRFRPDQR--LLEEGNIDGA---EEQKQRIEQLQRER--------------------
-----------------------RKVLQD----------NNMTHQPRFFKKSKD-------DTWISNNTYWELR------
-----------------RDSGFSKMDFSV--LW-------------------------------
>TETRAODON_OSBPL3
--------------------------------------------------------------------------------
--------------------------------------------------------------------SPTHSD-SSSSS
KPDGNQ-------------------------------------------------------DSWEIVEGLRGFS-ATMQE
PDRQEGFLLKRRKWPMKGWHKRYFGLEKGILKYAKSATDLKKGKLHGCIDVGLSVMSIKKKAMCIDLDTEANIFHLKIKT
QELFEEWVSKLRHHRVFRQNEIAMYPHERH-----------------LFYPHSS--PSLNES--------MKKQRSTLTK
QTSIH----------------QAKVSSWLHSSVDMDKCCKDLEECESYLLELNLLLKS----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------MEVLHRTYS------------APA-ISGLQASTFELPK-KEKRQ-RKWRSKNN
GKETKSTLQ-------------------------VPSCISSQSPRLHASNPNLSTTDSNTQELSPESL---DSPTEVSRL
QQDFCRLAYNIHGRLKSTLSTLLAERDRLRQTI-DLQAPQP--VQLMGLKNAYAS--------------------VSVST
IPKIPVRPVCPR----------------RYQECSDG-PHSLVHQASSESKASIP--ESISEFFDAKEYLLS-----SSSS
ENEVSDDD------------SYISD-----VSDSISMDTCSNEGTTERQNS----VSSVVALVR----------------
-RRSTLPSPRPSSS-VSLWNILRNNIGKDLSKVAMPVQLNEPIN-TLQRLCEELEYSELLDTANQ-TQDPYQRMVYVATF
AISAYASTYHRAGSKPFNPVLGETYECDR--PDKGFRFIAEQVK-HHPPVSACHSDSKNFTFWQDVRWK--NKFWGKSME
IVPMGTTHVTLPAFGDHYEWNKVTSCIHNILSGQRWIEHYG-EMAIKNLNSDACQCKITFVKANSWSSSVN-EIEGVVTD
SKGKVVHSIFGKWHESIFQGDPPTAM------------------------CIWRANPMPLDQEQYYG-------------
FTQFAMELNELDSSLRPLLPRTDTRFRPDQR--LLEEGNVDGA---EEQKQRIEQLQRER--------------------
-----------------------RKVLQD----------NNMTHKPRFFKKSNN-------DNWVSNNSYWDLR------
-----------------REPGFSKVDFPV--LW-------------------------------
>HUMAN_OSBPL6
--------------------------------------------------------------------------------
----------------------------------------------------MSSDEKGISPAHKTSTPTHRSASSSTSS
QRDSRQS---------------------IHILERTASSS-TEPSVSRQLLEPEPVPLSKEADSWEIIEGLKIGQ-TNVQK
PDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKS
QDWFDAWVSKLRHHRLYRQNEIVRSPRDASF----------------HIFPSTSTAESSPAANVSVMDGKMQPNSFPWQS
PLPCSN------SLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQN----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------LEILQRTQS------------APN-FTDMQANCVDISK-KDKRVTRRWRTKSV
SKDTKIQLQ-------------------------VPFSATMSPVRLHSSNPNLCAD-IEFQTPPSHLTDPLESSTDYTKL
QEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQMARLRQSLSQ-------------------ALNQNA
ELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQVANESRLSMS--ESVSEFFDAQEVLLS-----ASSS
ENEASDDE------------SYISD-----VSDNISEDNTSVADNISRQILNGELTG--GAFRN----------------
GRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLN-TLQHLCEEMEYSELLDKASE-TDDPYERMVLVAAF
AVSGYCSTYFRAGSKPFNPVLGETYECIR--EDKGFRFFSEQVS-HHPPISACHCESKNFVFWQDIRWK--NKFWGKSME
ILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYG-EVTIRNTKSSVCICKLTFVKVNYWNSNMN-EVQGVVID
QEGKAVYRLFGKWHEGLYCGVAPSAK------------------------CIWRPGSMPTNYELYYG-------------
FTRFAIELNELDPVLKDLLPPTDARFRPDQR--FLEEGNLEAA---ASEKQRVEELQRSR--------------------
-----------------------RRYMEE----------NNLEHIPKFFKKVIDANQR---EAWVSNDTYWELR------
-----------------KDPGFSKVDSPV--LW-------------------------------
>MOUSE_OSBPL6
--------------------------------------------------------------------------------
----------------------------------------------------MSSDEKGISPAHKTSTPTHRSASSSTSS
QRESRQS---------------------IHVLERTASSS-TEPSVSRQLLEPEPIPLSKEADSWEIIEGLKIGQ-TNVQK
PDRHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKS
QDWFDAWVSKLRHHRLYRQNEIVRSPRDASF----------------HIFPATSTAESSPAANVSVVDGKMQPNSFPWQS
PLPCSN------SLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQN----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------LEILQRTQS------------APN-FTDMQANCVDISK-KDKRVTRRWRTKSV
SKDTKIQLQEGPPAKGQFNTTRRRQRLAAAVATTVPFSATMSPVRLHSSNPNLCAD-IEFQTPPSHLTDPLESSTDYTKL
QEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQVVSEQDHNKGHSTQMARLRQSLSQSEGAGKSW-----------ALNQNA
ELRSRLNRIHSESTICDHVVSVNIIPSPDEPGEQIHVSLPLSQQVANESRLSMS--ESVSEFFDAQEVLLS-----ASSS
ENEASDDE------------SYISD-----VSDNISEDNTSVADNISRQILNGELTG--GAFRN----------------
GRRTCLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLN-TLQHLCEEMEYSELLDKASE-TDDPYERMVLVAAF
AVSGYCSTYFRAGSKPFNPVLGETYECIR--EDKGFRFFSEQVS-HHPPISACHCESKNFVFWQDIRWK--NKFWGKSME
ILPVGTLNVTLPKYGDYYVWNKVTTCIHNILSGRRWIEHYG-EVTLRNTKSSVCICKLTFVKVNYWNSNVN-EVQGVVID
QEGKVVHRLFGKWHEGLYCGVAPSAK------------------------CIWRPGSLPTNYELYYG-------------
FTRFAVELNELDPVLKDLLPPTDARFRPDQR--FLEEGNLEAA---AAEKQRVEELQRSR--------------------
-----------------------RRYMEE----------NNLEHIPKFFKKVIDANQR---EAWVSNDTYWELR------
-----------------KDPGFSKVDSPV--LW-------------------------------
>RAT_OSBPL6
--------------------------------------------------------------------------------
----------------------------------------------------MSSDEKGISPAHKTSTPTHRSALSSTSS
QRESRQS---------------------IHVLERTASSS-TEPSISRQLLEPEPIPLSKEADSWEIIEGLKIGQ-TNVQK
PDRHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKS
QDWFDAWVSKLRHHRLYRQNEIVRSPRDASF----------------HIFPATSTAESSPAANVSVVDGKMQPSSFPWQS
PLPCSN------SLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQN----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------LEILQRTQS------------APN-FTDMQANCVDISK-KDKRVTRRWRTKSV
SKDTKIQLQ-------------------------VPFSATMSPVRLHSSNPNLCAD-IEFQTPPSHLTDPLESSTDYTKL
QEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHNKGHSTQMARLRQSLSQ-------------------ALNQNA
ELRSRLNRIHSESTICDHVVSVNIIPSPDEPGEQIHANLPLSQQVVNESRLSMS--ESVSEFFDAQEVLLS-----ASSS
ENEASDDE------------SYISD-----VSDNISEDNTSVADNISRQILNGELTG--GAFRN----------------
GRRTCLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLN-TLQHLCEEMEYSELLDKASE-TDDPYERMVLVAAF
AVSGYCSTYFRAGSKPFNPVLGETYECIR--EDKGFRFFSEQVS-HHPPISACHCESKNFVFWQDIRWK--NKFWGKSME
ILPVGTLNVTLPKYGDYYVWNKVTTCIHNILSGRRWIEHYG-EVTIRNTKSSVCICKLTFVKVNYWNSNVN-EVQGVVID
QEGKVVHRLFGKWHEGLYCGVAPSAK------------------------CIWRPGSLPTNYELYYG-------------
FTRFAVELNELDPVLKELLPPTDARFRPDQR--FLEEGNLEAA---AAEKQRVEELQRSR--------------------
-----------------------RRYMEE----------NNLEHIPKFFKKVIDANQR---EAWVSNDTYWELR------
-----------------KDPGFSKVDSPV--LW-------------------------------
>COW_OSBPL6
--------------------------------------------------------------------------------
----------------------------------------------------MSSDEKGISPAHKTSTPTHRSASSSTSS
QRDSRQS---------------------IHILERTSSTS-TEPSVSRQLLEPEPVPLSKEADSWEIIEGLKIGQ-TNVQR
PDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKS
QDWFDAWVSKLRHHRLYRQNEIVRSPRDASF----------------HIFPSTSTAESSPAANVSVVDGKVQPNSFPWQS
PLPCSS------SLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQN----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------LEILQRTQS------------APN-FTDMQANCVDISK-KDKRVTRRWRTKSV
SKDTKIQLQ-------------------------VPFSATMSPVRLHSSNPNLCAD-IEFQTPPSHLTDPLESSTDYTKL
QEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHNKGHSTQMARLRQSLSQ-------------------ALNQNA
ELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQVANESRLSMS--ESVSEFFDAQEVLLS-----ASSS
ENEASDDE------------SYISD-----VSDNISEDNTSVADNISRQILNGELTG--GAFRN----------------
GRRTCLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLN-TLQHLCEEMEYSELLDKASE-TDSPYERMVLIAAF
AVSGYCSTYFRAGSKPFNPVLGETYECIR--EDKGFRFFSEQVS-HHPPISACHCESKNFVFWQDIRWK--NKFWGKSME
ILPVGTLNVMLPKYGDCYVWNKVTTCIHNILSGRRWIEHYG-EVTVRNTKSSVCICKLTFVKVNYWNSNVN-EVQGVVMD
QEGKVVHRLFGKWHEGLYCGVAPSAK------------------------CIWRPGSMPTNYELYYG-------------
FTRFAIELNELDPVLKDLLPPTDARFRPDQR--FLEEGNLEAA---AAEKQRVEELQRSR--------------------
-----------------------RRYMEE----------NNLEHIPKFFKKVIDANQR---EAWVSNDTYWELR------
-----------------KDPGFSKVDSPV--LW-------------------------------
>OP0SSUM_OSBPL6
--------------------------------------------------------------------------------
----------------------------------------------------MSSEEKGISPAHKTSTPTHRSASSSSSS
QRESRQS---------------------VHILERNASTG-NEPSASRQLLETEPVSLSKEADSWEIIEGLKIGQ-TNVQK
PDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKS
QDWFDGWVSKLRHHRLYRQNEIVRSPRDASF----------------HIFPSTSTTESSPAANVAVMDGKVQQNSFPWQP
PIPCSN------SLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQN----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------LEILQRTQS------------APN-FTDMQANCVDISK-KDKRVTRRWRTKSV
SKDAKIQLQ-------------------------VPFSATMSPVRLHSSNPNLCAD-IEFQTPPSHLADPLETSTDYTKL
QEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHNQGHNPQMARLRQSLSQ-------------------ALNQNA
ELRSRLNRIHSESIICDQVVSVNIIPSPDEPGEQIHVSLPLSQQAANESRLSMS--ESVSEFFDAQEVLLS-----ASSS
ENEASDDE------------SYISD-----VSDNISEDNTSVADNISRQILNGELTG--GAFRN----------------
GRRTCLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLN-TLQHLCEEIEYSELLDKASE-TDDPYERMVLIAAF
AVSGYCSTYFRAGSKPFNPVLGETYECIR--EDKGFRFFSEQVS-HHPPISACHCESKNFVFWQDIRWK--NKFWGKSME
ILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYG-EITIRNTKSSICICKLTFVKVNYWNSNVN-EVQGVVMD
QEGKVVHRLFGKWHEGLYCGVAPSAK------------------------CIWRPGSMPTNYELYYG-------------
FTRFAIELNELDPVLKDLLPPTDARFRPDQR--FLEEGNLEAA---AAEKLRVEELQRSR--------------------
-----------------------RRYMEE----------NHLEHIPKFFKKVIDANQR---EAWVSNDTYWELR------
-----------------KDPGFSKVESPV--LW-------------------------------
>PLATYPUS_OSBPL6
--------------------------------------------------------------------------------
----------------------------------------------------MSSEEKGVSPAHKTSTPTHRSASSSSSS
QRESRQG---------------------GYILERNASAG-HEPSVSRQFLENEPVSLSKEADSWEIIEGLKIGQ-TNVQK
PDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPMDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKS
QDWFDAWVSRLRHHRLYRQNEIVRSPRDASF----------------HIFPSTSTTESSPAANMAMVDGKVQPNSFLWQP
PLPCSS------SLPATCTSGQSKVVAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQN----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------LEILQRTQS------------APN-FTDMQANCVDMSK-KDKRVTRRWRTKSV
SKDAKIQLQ-------------------------VPFSATMSPVRLHSSNPNLCAD-IEFQTPPSHLADPLESSTDYTKL
QEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDLNKGHSAQMARLRQSLSQ-------------------ALNQNA
ELRSRLNRIHSESVICDQVVSVNIIPSPDEPGEQIHVSLPLTQQAANESRLSMS--ESVSEFFDAQEVLLS-----ASSS
ENEASDDE------------SYISD-----VSDNISEDNTSVADNISRQILNGELTG--GAFRN----------------
GRRTCLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLN-TLQHLCEEVEYSELLDKASE-TDDAYERMVLIAAF
AVSGYCSTYFRAGSKPFNPVLGETYECIR--EDKGFRFFSEQVS-HHPPISACHCESKNFVFWQDIRWK--NKFWGKSME
ILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYG-EVTIRNTKSSVCICKLTFVKVNYWNSNVN-EVQGVVMD
QEGKVVHRLFGKWHEGLFCGVAPSAK------------------------CIWRPGSMPTNYELYYG-------------
FTRFAIELNELDPVLKDLLPPTDARFRPDQR--FLEEGDLEAA---ASEKQRVEELQRSR--------------------
-----------------------RRYMEE----------NHLEHIPKFFKKVTDANQR---EAWVSNDTYWGLR------
-----------------KEPGFSKVESPV--LW-------------------------------
>CHICKEN_OSBPL6
--------------------------------------------------------------------------------
----------------------------------------------------MSSEEKSISPAHKTSTPSHRSASSSSSS
QRDRRQS---------------------VNLLERKASSGSTDPSLSKQFLEADPISLSKEPDSWEIIEGLKIGQ-TNVQK
PDKHEGFMLKKRKWPLKGWHKRFFVLDNGLLKYSKSPIDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKS
QDTFDAWVSKLRHHRLYRQNEIVRSPRDASF----------------HIFPSASTTESSPAANVP--DGKVQQNSFPWQS
PIPCSN------SLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQN----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------LEILQRTQS------------APN-FTDMQANCVDISK-KDKRVTRRWRTKSV
SKDAKIQLQ-------------------------VPFSATMSPVRLHSSNPNLCAD-IEFQTPPSHVTDPLECSTEYMKL
QEEFCLMAQKVHSLLKSAFNSIAIEKEKLKQIVSEQDLT-GHNAQIAHLRQSLSQ-------------------ALNQNA
ELRSRLNRIHSESVICDQVVSVNIIPSPDETGEQIHVSLPLSQQVSNESRLSMS--ESVSEFFDAQEVLLS-----ASSS
ENEASDDE------------SYISD-----VSDNISEDNTSVAD-ISRQIVNGELTG--GAFRN----------------
GRRTCLPAPSPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLN-TLQHLCEELEYSELLDKAAE-TDDPYERMVLIAAF
AASGYASTYFRAGSKPFNPVLGETYECIR--EDKGFRFFSEQVS-HHPPISACHCESKNFVFWQDIRWK--NKFWGKSME
ILPVGTLNVTLPKYGDYYVWNKVTTCIHNILSGRRWIEHYG-EITIRNTKSSVCICKLTFVKVNYWNSNVN-EVQGVVID
QEGKVVHRLFGKWHEGLYCGVAPSAK------------------------CVWRPGSMPTNYERYYG-------------
FTRFAIELNELDPVLKDLLPTTDARFRPDQR--LLEEGNIEAA---ASEKQRIEELQRSR--------------------
-----------------------RRYMEE----------NSIEYVPKFFKKVIDANQR---EAWVTNETYWELR------
-----------------KDPGFSKVEIPV--LW-------------------------------
>ANOLE_LIZARD_OSBPL6
--------------------------------------------------------------------------------
----------------------------------------------KNLAAKMSSEEKGISPAHKTSTPSHKSASSSSSS
QRDSRQS---------------------GHILERNISSGSADLVMGKQLLENEPVIISKEPDNWEIIEGLKIGQ-TNVQK
PDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKSPIDTQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKS
QDSFDAWVSRLRHHRLYRQNEIVRSPRDASF----------------HIFPSTSTTESSPAANVAMLEAKVSQNNFPWQP
PIPCSNSL---SPLPATCTTGQSKVVAWLQDSEEMDRCSEDLAHCQSNLVELSKILQN----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------LEILQRTQS------------APN-FTDMQANCVD--K-KDKRVTRRWRTKSV
SKDAKIQLQEGTTLKSQFSSARRRQRLAAAVATTVPFSSTMSPVRLHSSNPNLCAD-IEFQMPPSHVADPLETSTDYIKL
QEEFCLMAQKVHSLLKSAFNSIAIEKEKLKQMVSEHDFT-GHSTQITRLRQSLSQ-------------------ALNQNA
ELRSRLNRIHSDSVLCDQVVSVNIIPSPDESGEQIHVSLPLSQQVSHESRLSMS--ESVSEFFDAQEVLLS-----ASSS
ENEASDDE------------SYISD-----VSDNISEDNTSVADNISRQILNGELSG--GAFRN----------------
GRRTCLPSPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLN-TLQHLCEELEYSELLDKAAE-SDDPYERMVLIAAF
ATSGYASTYYRAGSKPFNPVLGETYESIR--EDKGFRFFSEQVS-HHPPISACHCESKNFVFWQDIRWK--NKFWGKSME
ILPIGTLNVTLPKYGDCYVWNKVTTCIHNILSGRRWIEHYG-EITIRNTKSGVCICKLTFMKVNYWNSNVN-EVHGVIMD
QEGKVVHRLFGKWHEGLYCGVGPSAK------------------------CIWRPGSMPTNYERYYG-------------
FTRFAIELNELDPALKDLLPRTDARFRPDQRQEFLEEGHLEAA---ATEKQRIEELQRSR--------------------
-----------------------RRYLEE----------NHMEHVPRFFKKVIDANQR---EAWVSNDTYWELR------
-----------------KDPGFSKIETLK--LW-------------------------------
>ZEBRAFISH_OSBPL6
--------------------------------------------------------------------------------
-------------------------------------MSRHQSRTTSLEEKVATPIHRSTAPLQKSSTPTHKSASSSSSS
QRDSRQ-----------------------------------------------------EPDSWEIIEGLRIGQ-THVQR
PEKHEGFMLKKRKWPLKGWHKRFFVLDNGILKYSKSPVDIQKGKLHGSIDVGLSVMSIKKRARRIDLDTEEHIYHLKVKS
PDVFDLWVCKLRHHRLFRQNEIVRSPRDATL----------------RTFPPSAGAESPQNTPSSTHPKKQGKPSS----
----FPW-----QLPPSCSNGQSKVAAWLQESEEMDKCAEELAYCQSSLLELNQLLQS----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------LEILQRTQS------------APN-FTDMQSNCVDLSK-KEKRVSRRWRTKSV
SKDAKLQQQ-------------------------VPLSASMSQVRLHSSNPNLCAELADFQAPVTRLTDGIDSAGDYIKL
QEDFCIIAQKVHSLLKSAFNTVAIEKEKIKQVLLDHEQT-GQSNQIVTLRRSLSQ-------------------ALSQNA
ELKTRLNRIHSESVLSEQVVSVNIISSPDEACEPLHVGLPLSQQVSNESRLSMS--ESVSEFFDAQEVLLS-----ASSS
ENEASDDE------------SYVSD-----VSDNISEDNASVTDNVSRQMPNGELAS--SMFRN----------------
GRRPCLPAPAPDTSNINLWNILKNNIGKDLSKVSMPVELNEPLN-TLQHMCEELEYTELLDKAAQ-TDDPYERMAIVAAF
AVSGYSSTYYRAGSKPFNPLLGETYECIR--EDK--------VS-HHPPISACHCDSQNFTFWQDVRWK--NKFWGKSME
ILPIGTVNVMLPSYGDHYEWNKVTTCVHNILSGRRWIEHYG-EVTIRNTRSTTCICKLSFIKGNYWSSNVN-EVQGSVMD
QEGRVIHRLFGKWHEGLYCGVPPSAK------------------------CIWRPGSMPTDYELYYG-------------
FTRFAVELNELFPEMKELLPPTDARFRPDQR--FLEEGNVQMA---TAEKQRIEEQQRNR--------------------
-----------------------RKWMEE----------NNIKHQPRFFKKVMDSNQR---ERWVSNSMYWELR------
-----------------KDPGFLKLENPE--LW-------------------------------
>FUGU_OSBPL6
--------------------------------------------------------------------------------
----------------------------------------------------LSSEERTPTSINKTSTPVHKSASSSSSS
QRDSRQ-----------------------------------------------------EPDSWEIIEGLKIGQ-SNVQR
PDKHEGFMLKKRKWPLKGWHKRFFVLDNGILKYSKSPIDIQKGKLHGSIDVGLSVMSIKKRARRIDLDTEEHIYHLKIKS
QDIFDAWVSKLRHHRLYRQNEIVRSPRDATM----------------RTFPPPAAVESPQPTLSVVREAKCSNATY----
GTIVQCH-----SNVSHNGNGQSKVVAWLQESEEMDKCAEELARCQSNLTELSRLLQS----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------LEILQRTQS------------APN-FIEMQTNCVEISK-KEKRLNRRWRTKSV
GKDAKFQLQ-------------------------VPLSASMSPIRLHSSNPNLCAELVDFQPPVSRLTDSVECSSDYIKL
QEEFCTIAQKVHSLLKSAFNTVAIEKEKIKQILSDQEQS-DQSSQINSLRKSLSQ-------------------ALSQNT
ELRTRLNRIHSESILTEQVVSVNIISTPDEAEEQM--GIPLTQQASNESRLSMS--ESVSEFFDAQEVLLS-----ASSS
ENEGSDDE------------SYVSD-----VSDNISEDNASVTDNISRQMANGDFAG--SAFRN----------------
GRRTCLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLN-TLQRMCEEVEYSELLDKAAD-TEDPFERMVLVAAF
AVSGYSSTYYRAGSKPFNPLLGETYECIR--EDKGFCFFSEQVS-HHPPISACHCESKNFTFWQDVRWK--NKFWGKSME
ILPIGTVNLTIPRFGDHYEWNKVTTCVHNILSGRRWIEHYG-EITIRNMKSSACLCKLTFIKGNYWSSNVN-EVQGFVMD
QEGKVIHRLFGKWHEGLYCGVPPSAK------------------------CVWRPGSMPTDYELYYG-------------
FTRFAIELNELCPELKDVLPRTDTRFRPDQR--YLEEGNLEMA---SSEKQRIEDLQRTR--------------------
-----------------------RRWRED----------SNVKQEPCFFKKVVDANHR---ERWVSNNTYWELR------
-----------------KNPGFINMECAVS-LW-------------------------------
>STICKLEBACK_OSBPL6
--------------------------------------------------------------------------------
---------------------------------------------RGVHGRTMSTEERSSPPVLKSSTPVHKSASSSSSS
QRDSRQ----------------------FMHLTDLKTLTAQLKSLKHQLCFPQIQRQLQEADSWEIIEGLKIGQ-SNVQR
PDKHEGFMLKKRKWPLKGWHKRFFVLDNGILKYSKSPIDIQKGKLHGSIDVGLSVMSIKKRARRIDLDTEEHIYHLKVKS
QDIFDAWVSKLRHHRLYRQNEIVRSPREATM----------------RTFPPPAAKESPKPAPSEVREAKAKPSSLPWQP
VAPSSNS-----SLPASYSNGQSKVVAWLQESEEMDKCAEELARCQSNLTELSRLLQS----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------LEILQRTQS------------APNSTCVTKTNCVEMSK-KEKRLNRRWRTKSV
GKDAKFQLQVQDTQTHSTCKCPLVVS------LQVPLSASMSPVRLHSSNPNLCAELVDFQPPVTRLTDSTECASDYIKL
QEEFCTIAQKVHSLLKSSFNTVAIEKEKIKQILSDQEQS-DQSAQINSLRKSLSQ-------------------ALSQNA
ELRTRLNRIHSESVLTEQVVSVNIISTPEQAGDQM--GIPLTQQASNESRLSMS--ESVSEFFDAQEVLLS-----ASSS
ENEGSDDE------------SYVSD-----VSDNISEDNASVTDNVSRQMANGDFAG--SAFRN----------------
GRRSCLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLN-TLQRMCEELEYSELLDKAAE-TEDPLERMVVVAAF
AVSGYSSTYYRAGSKPFNPLLGESYECIR--EDKGFCFFSEQVVSHHPPISACHCESKNFTFWQDVRWK--NKFWGKSME
VLPIGTVNLMIPRFGDQYEWNKVTTCVHNILSGQRWIEHYG-EITIRNTKSSACLCKLTFVKGNYWSSNVN-EVQGFVMD
QEGKVVHRLFGKWHEGLYCGVPPSAK------------------------CIWRPGSMPTDYELYYG-------------
FTRFAIELNELCPELKDVLPRTDARFRPDQR--HLEEGNLEMA---SSEKQRIEDLQRVR--------------------
-----------------------RKCNDE----------NNVKLEPRFFKKVVDGNHR---ERWVSNNTYWELR------
-----------------KNPGFINMESTMN-LW-------------------------------
>TETRAODON_OSBPL6
--------------------------------------------------------------------------------
---------------------------------------------RGPTGRTLSSEERNSTAINKTSTPVHKSASSSSSS
QRDSRQQNIE-----------------YLNSTAFGSSVGTTSPSAVREIFQSDLLLQQKEPDSWEIIEGLKIGQ-SHVQR
PDKHEGFMLKKRKWPLKGWHKRFFVLDNGILKYSKSPIDIQKGKLHGSIDVGLSVMSIKKRARRIDLDTEEHIYHLKIKS
QDIFDAWVSRLRHHRLYRQNEIVRSPREATV----------------RTFPPPAAVESPQPTSSVVREAKQQAKPS----
SLPWQQA-----ALPASYSNGQSKVVAWLQESEEMDKCAEELARCQSSLTELSRLLQS----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------LEILQRTQS------------APN-FTEMQTNCVEISK-KEKRLNRRWRTKSV
GKDAKFQLQPSPPLGVRFSFSLVFLSLYSALCLTVPLSASMSPIRLHSSNPNLCAELVDFQPPISRLTDSVECSSDYIKL
QEEFCTIAQKVHSLLKSAFNTVAIEKEKIKQILSDQEQS-DQSAQISSLRKSLSQ-------------------ALSQNT
ELRTRLNRIHSESILTEQVVSVNIISTPDEAEEQM--GIPLTQQASNESRLSMS--ESVSEFFDAQEVLLS-----ASSS
ENEGSDDE------------SYVSD-----VSDNISEDNASVTDNISRQMANGDFAG--SAFRN----------------
GRRTCLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLN-TLQRMCEELEYSELLDKAAD-TEDPFERMVLVAAF
AVSGYSSTYYRAGSKPFNPLLGETYECIR--EDKGFCFFSEQVS-HHPPISACYCESKNFTFWQDMRWK--NKFWGKSME
ILPIGTVNLTIPRFGDHYEWNKVTTCVHNILSGQRWIEHYG-EVTIRNTKSSACLCKLTFVKGNYWSSNVN-EVQGFVMD
QEGKAIHRLFGKWHEGLYCGVPPSAK------------------------CVWRPGSMPTDYELYYG-------------
FTRFAIELNELCPELKDVLPRTDTRFRPDQR--YLEEGNLEMA---SSEKQRIEDLQRTR--------------------
-----------------------RRCRED----------SNSKLEPSFFKKVVDTNHR---ERWVSNNTYWELR------
-----------------KNPGFINMERAVS-LW-------------------------------
>HUMAN_OSBPL7
--------------------------------------------------------------------------------
----------------------------------------------------MDFQERDPPFLPESAQSSKPSSAQQAS-
-------------------------------------------------------------ELWEVVEEPRVRLGTEGVM
PERQEGHLLKKRKWPLKGWHKRYFVLEDGILHYATTRQDITKGKLHGSIDVRLSVMSINKKAQRIDLDTEDNIYHLKIKS
QDLFQSWVAQLRAHRLAHRLDMPRG--SLPS----------------TAHRKVPGAQLPTAATASALPGLGP--------
---------------------REKVSSWLRDSDGLDRCSHELSECQGKLQELHRLLQS----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------LESLHRIPS------------APVIPTHQASVTTERPK-KGKRTSRMWCTQSF
AKDDTIGRV----------------------------------GRLHGSVPNLSRYLESRDSSGTRGL----PPTDYAHL
QRSFWALAQKVHSSLSSVLAALTMERDQLRDMHQGSELSRMGVSEASTGQRRLHSL------------------STSSDT
TADSFSSLNPEE------------------QEALYMKGRELTPQLSQTSILSLA--DSHTEFFDACEVLLS-----ASSS
ENEGSEEEE-----------SCTSE-----ITTSLSEEMLDLR-GAERCQKGG---CVPGRPMG---------------P
PRRRCLPAASGPGADVSLWNILRNNIGKDLSKVSMPVQLNEPLN-TLQRLCEELEYSSLLDQASR-IADPCERMVYIAAF
AVSAYSSTYHRAGCKPFNPVLGETYECER--PDRGFRFISEQVS-HHPPISACHAESENFAFWQDMKWK--NKFWGKSLE
IVPVGTVNVSLPRFGDHFEWNKVTSCIHNVLSGQRWIEHYG-EVLIRNTQDSSCHCKITFCKAKYWSSNVH-EVQGAVLS
RSGRVLHRLFGKWHEGLYRGPTPGGQ------------------------CIWKPNSMPPDHERNFG-------------
FTQFALELNELTAELKRSLPSTDTRLRPDQR--YLEEGNIQAA---EAQKRRIEQLQRDR--------------------
-----------------------RKVMEE----------NNIVHQARFFRRQTDSSGK---EWWVTNNTYWRLR------
-----------------AEPGYGNMDGAV--LW-------------------------------
>MOUSE_OSBPL7
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------------M
PERQEGHLLKKRKWPLKGWHKRYFVLEDGILHYATTRQDITKGKVHGSIDVRLSVMSINKKAQRIDLDTEDNIYHLKIKS
QDLFHSWVAQLRAHRLAQRLDMP-------S----------------ATHRKAPGTQMLTAGSASALPGVGP--------
---------------------REKVSSWLRDSDGLDRCSHALSECQGKLQELHRLLQS----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------LESLHRIPS------------APVIPTHQTSVTTERPK-KGKRTSRMWCTQGF
AKDDTIGRV----------------------------------GRLHGSVPNLSRYLESRDTSGPRGL----PPPDYAHL
QRSFWALAQKVHNSLSSVLVALTTERDRLRDLHQGSELSRMVVSEAPDGQRRLHSL------------------SISSDT
TADSFSSLNPEE------------------QEALYMKGRELTPQLSQSSVLSLA--DSHTEFFDACEVLLS-----ASSS
ENE-VREEG-----------SCASE-----ITTSLSEEVLDIR-GADRYQKGP---CVPGIAVG---------------P
PRRRCLPAASGPGTDVSLWNILRNNIGKDLSKVSMPVQLNEPLN-TLQRLCEELEYSSLLDQASR-MADPCERMVYIAAF
AVSAYSSTYHRAGCKPFNPVLGETYECER--PDRGFRFISEQVS-HHPPISACHAESENFIFWQDMKWK--NKFWGKSLE
IVPVGTVNVSLPRFGDHFEWNKVTSCIHNILSGQRWIEHYG-EVLIRNTQDSSCHCKITFCKAKYWSSNIH-EVQGAVLS
RSGRVLHRLFGKWHEGLYRGPPPGGQ------------------------CIWKPNSMPPDHERNFG-------------
FTQFALELNELTSELKRTLPSTDTRLRPDQR--YLEEGNIQAA---EAQKRRIEQLQRDR--------------------
-----------------------RRVMEE----------NNIVHQARFFRRQTDSSGK---EWWVTNHTYWRLR------
-----------------AEPGYGNLDGAV--LW-------------------------------
>RAT_OSBPL7
--------------------------------------------------------------------------------
----------------------------------------------------MDFQERDTPSLAESTQSSKPSSTQQAS-
-------------------------------------------------------------ELWEVVEEPRGRLGAEDIM
PERQEGHLLKKRKWPLKGWHK------------------ITKGKVHGSIDVRLSVMSINKKAQRIDLDTEDNIYHLKIKS
QDLFQSWVSQLRAHRLAQRSDLP-------N----------------ATHRKAPGTQTLTAGSASALPGVGP--------
---------------------REKVSSWLRDSDGLDRCSHALSECQGKLQELHRLLQS----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------LESLHRIPS------------APVIPTHQASVTTERPK-KGKRTSRMWCTQGF
AKDDTIGRV----------------------------------GRLHGSVPNLSRYLESRDTSGPRGL----PPPDYAHL
QRSFWALAQKVHNSLSSVLVALTTERDRLRDLHQGSELSRMAVSEAPDGQRRLHSL------------------SISSDT
TADSFSSLNPEE------------------QEALYRKGRELTPQLSQSSVLSLA--DSHTEFFDACEVLLS-----ASSS
ENEGSEEEE-----------SCASE-----ITTSLSEEVLDIR-GADRYPKGA---CVPGIAVG---------------P
PRRRCLPAASGPGTDVSLWNILRNNIGKDLSKVSMPVQLNEPLN-TLQRLCEELEYSSLLDQASR-MADPCERMVYIAAF
AVSAYSSTYHRAGCKPFNPVLGETYECER--PDRGFRFISEQVS-HHPPISACHAESENFIFWQDMKWK--NKFWGKSLE
IVPVGTVNVSLPRFGDHFEWNKVTSCIHNILSGQRWIEHYG-EVLIRNTQDSSCHCKITFCKAKYWSSNIH-EVQGAVLS
RSGRVLHRLFGKWHEGLYRGPPPGGQ------------------------CIWKPNSMPPDHERNFG-------------
FTQFALELNELTAELKRTLPSTDTRLRPDQR--YLEEGNIQAA---EAQKRRIEQLQRDR--------------------
-----------------------RRVMEE----------NNIVHQARFFRRQTDSSGK---EWWVTNHTYWRLR------
-----------------AEPGYGNLDGAV--LW-------------------------------
>COW_OSBPL7
--------------------------------------------------------------------------------
----------------------------------------------------MDFQEWDPPSLAESTQSAKPSGAQQAS-
-------------------------------------------------------------ELWEVVEEPRGRLGAEGIM
PERQEGHLLKKRKWPLKGWHKRYFVLEDGILHYATTRQDITKGKLHGSIDVRLSVMSINKKAQRIDLDTEDNIYHLKIKS
QDLFQSWVAQLRAHRSAQHLDVPRS--LLPS----------------TAHWKVTGAQPAVSGSASALPGVGP--------
---------------------REKVSSWLRDSDGLDRCSHELSECQGKLQELHRLLQS----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------LESLHRIPS------------APVIPTHQASVTTERPK-KGKRTSRMWCTQSF
AKDDTIGRV----------------------------------GRLHGSVPNLSRYLESRDPSGPRGL----PPPDYAHL
QRSFWALAQKVHSSLSSVLAALTAERDRLRDLHPGSEPSRLGVSETSAGPRRLHSL------------------SISSDT
TADSFSSLNPEE------------------QEALYMKGRELTPQLSQSSVLSLA--DSHTEFFDACEVLLS-----ASSS
ENEGSEEEE-----------SCTSE-----VTTSLSEEVLDLR-GAERCQKEGQATCVPGAAVG---------------P
PRRRCLPAASGPGTDVSLWNILRNNIGKDLSKVSMPVQLNEPLN-TLQRLCEELEYSSLLDRASR-TADPCERMVYIAAF
AVSAYSSTYHRAGCKPFNPVLGETYECER--PDRGFRFISEQVS-HHPPISACHAESENFIFWQDMKWK--NKFWGKSLE
IVPVGTVNVSLPRFGDHFEWNKVTSCIHNILSGQRWIEHYG-EVLIRNTQDSSCHCKLTFCKAKYWSSNVH-EVQGAVFS
RSGRVLHRLFGKWHEGLYRGPPPGGQ------------------------CIWKPNSMPPNYERNFG-------------
FTQFALELNELTAELKRSLPSTDTRLRPDQR--YLEEGNIQAA---EAQKRRIEQLQRDR--------------------
-----------------------RKVMEE----------NNIVHQARFFRRQTDSSGK---EWWVTNNTYWQLR------
-----------------AEPGYGNLDGAV--LW-------------------------------
>HORSE_OSBPL7
--------------------------------------------------------------------------------
----------------------------------------------------MDFQERVPPSLAVSTQSAKPGSVQQVS-
-------------------------------------------------------------ELWEVVEEPRGRLGAEGIM
PERQEGHLLKKRKWPLKGWHKRYFVLEDGILHYATTRQDITKGKLHGSIDVRLSVMSINKKAQRIDLDTEDNIYHLKIKS
QDLFQSWVAQLRAHRLAQRLDMPRG--SLPS----------------TTHRKAPGAQLPTASGASALPGVGS--------
---------------------REKVSSWLRDNDGLDRCSHELSECQGKLQELHRLLQS----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------LESLHRIPS------------APVIPTHQASVTTERPK-KGKRTSRMWCTQSF
AKDDTIGRV----------------------------------GRLHGSVPNLSRYLESRDPSGSRGL----PPPDYAHL
QRSFWALAQKVHSSLSSVLAALTAERDRLRDLHQGSELSRMGVSEASAGPRRLHSL------------------SISSDT
TADSFSSLNPEE------------------QEALYMKGRELTPQLSQSSILSLA--DSHTEFFDACEVLLS-----ASSS
ENEGSEEEE-----------SCTSE-----VTTSLSEEVLDLR-LAERCQKGG---CVPGRAAG---------------P
PRRRCLPAASGPGADVSLWNILRNNIGKDLSKVSMPVQLNEPLN-TLQRLCEELEYSSLLDQASR-ITDPCERMVYIAAF
AVSAYSSTYHRAGCKPFNPVLGETYECER--PDRGFRFISEQVS-HHPPISACHAESENFIFWQDMKWK--NKFWGKSLE
IVPVGTVNVSLPRFGDHFEWNKVTSCIHNILSGQRWIEHYG-EVLIRNTQDSSCHCKITFCKAKYWSSNVH-EVQGAVFS
RSGRVLHRLFGKWHEGLYRGPPPSSQ------------------------CIWKPNSMPPDHERNFG-------------
FTQFALELNELTAELKRSLPSTDTRLRPDQR--YLEEGNIQAA---EAQKRRIEQLQRDR--------------------
-----------------------RRVMEE----------NNIIHQARFFRRQTDSSGK---EWWVTNNTYWRLR------
-----------------AEPGYGNLDGAV--LW-------------------------------
>OPOSSUM_OSBPL7
--------------------------------------------------------------------------------
-------------------------------------------------------------------------MGTTGL-
-------------------------------------------------------------ELWELVEEPQGRLGTEGTQ
PGRQEGPLLKKRKWPLKGWHKRYFVWDLPMLFNSSRNVSYAKGKLHGSIDVRSSVMSINKKAQRIDLDTEDNIYHLKIKS
QELFQSWVARLCAHRMAQRPDMARCPKLPAS----------------STNRKTSSARLAST---DNMPALGS--------
---------------------QDKVSTWLKDSEGLDRCSHELSECQGKLQELHKLLQS----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------LESLHRIPS------------APVISTNQ------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------QEALYMKGRELTPQLSQRSVLSLA--DSHTEFFDACEVFLS-----ASSS
ENEGSEEE------------SCTSE-----VTTSLSEEVLDIG-STEHCQKGA----SPGGAGV---------------P
PRRRCLPAASGPGTDVSLWNILRNNIGKDLSKVSMPVQLNEPLN-TLQRLCEELEYSNLLDQASR-TPDPCERMLYIAAF
AVSAYSSTYHRAGCKPFNPVLGETYECER--PDRGFRFISEQVS-HHPPISACHAESDNFIFWQDMKWK--NKFWGKSLE
IVPVGTVNVRLPRFGDHFEWNKVTSCIHNILSGQRWIEHYG-EVLIRNTQDSSCHCKITFCKAKYWSSSVH-EVQGAVFS
RSGRVIHRLFGKWHEGLYRGPPPGGQ------------------------CIWKPNLMPQDHERNFG-------------
FTQFALELNELTAELKRSLPSTDTRLRPDQR--YLEEGNIQAA---ESQKRRIEQLQRDR--------------------
-----------------------RKVMEE----------NNITHQARFFRRQTDGNGK---EWWVTNNTYWRLR------
-----------------AEPGYGNLDGAV--LW-------------------------------
>ANOLE_LIZARD_OSBPL7
--------------------------------------------------------------------------------
------------------------------------------------------------------------------S-
-------------------------------------------------------------ESWEVVDELQIQGGVIQE-
PERQEGYLLKKRKWPLKGWHKRYFVLEDGILKYATTRQDVLKGKLHGSIDVRLSVMSVNKKAQRVDLDTEDNIYHLKIKS
QELFNNWVAKLCSHRQAEKFLMGKMD--FPN----------------TLNHGNARHRILMSESAPALSSMGSH-------
---------------------RDKVNSWLSDSKGLDRCSAELTECQEKLQELNRMLQS----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------LDSLHRIPS------------APLISNSQTSTSTERPR-KGKRSTRIWCTQSF
AKDDTIGRV----------------------------------GRLHGSVPNLSRYLESCQNQAIFSV----PP-EYSQL
QRSFWILAQKVHGSLTSVLAVLSAERGRLQELQQTLDLQRLTLDN-PECIRRFHSL------------------SISSDT
TLDSFASFNPDEP-----------------NNTLLVKSQEQ--QLSNRSIVSLS--DSHTEFFDACEVFLS-----ASSS
ENEATDDE------------SCVSE-----VTNSISEEMAEVAGGPGRYTSGS----QPGKGPG---------------I
MRRNCLPASHVHASDVSVWNILRNNIGKDLSKVSMPVQLNEPLN-TLQRLCEELEYSALLDAASR-TLDPCERLICMAAF
AVSAYASTYFRAGSKPFNPVLGETYECVR--PDKGFRFISEQVC-HHPPVSACHAESDNFVFWQDMKWK--NKFWGKSLE
IIPVGTVNVHLPRFGDHYEWNKVTSCIHNILSGQRWIEHYG-EVLIRNTRDSTYHCKLTFCKARYWGSGVN-EVQGAILS
HSGKVIHRLFGKWHDGLYRGVAPVGK------------------------CIWRPNPMPRDYEKNYG-------------
FTQFALELNELTPELKRLLPSTDTRLRPDQR--YLEEGNAQAA---ESQKRRIEQLQRDR--------------------
-----------------------RRVMDD----------NNILHQARFFRRQVDANGK---ESWVSNSSYWKLR------
-----------------GEPGFSNMDSAV--LW-------------------------------
>HUMAN_OSBPL8
----------------------------MEGGLADGEPDRTSLLGDSKDVLGPSTVVANSDESQLLTPGKMSQRQGKEAY
PTPTKDLHQ-----------PSLSPASPHSQGFERGKEDIS------------QNKDESSLSMSKSKSESKLYNGSEKDS
STSSK--------------------------------------------LTKKESLKVQKKNYREEKKRATKELLSTITD
PSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLIYKTQKNGQ--WVGTVLLNACEIIERPSKKDGFCFKLFHPLEQSIWAV
KGPKGEAVG-SITQPLPSSYLIIRATS---------------ESDGRCWMDALELALKCSSLLKRTMIREGKEHDLSVSS
DSTH-----------VTFYGLLRANNLHSGDNFQLNDSEIERQHFKDQDMYSDKSDKEN---------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------DQEHDESDNEVMGKSEESDTDTSERQDDS
YIEP-------------------------------------EPVEPLKETTYTEQS-HEELGEAGEASQTETVSEENKSL
IWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALE-------------------------------
------------------------------ENPYFRLKKVVKWYLSGFYKKPKGLKKPYNPILGETFRCLWIH---PRTN
SKTFYIAEQ---------------------VSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGN----------------
-SLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAILEFKLKPFLGSSDCVNQISGK
LKLGKEVLATLEGHWDSEVFITDKKT------DNSEVFWNPTPDIKQWRLIRHTVKFE----EQGDFES--EKLWQRVTR
AINA-KDQTEATQEKYVLEEAQRQAARDRKTKNEEWSCKLFELD------PLTGEWHYKFADTRPWDPLN----DMIQFE
KDGVIQTKVKHR-TPMV------------------------------------SVPKMKHKPTRQ---------------
-QKKVAKGYSSPEPDIQDSSGSEAQSVKPSTR-RKKGIELG------DIQSSIESIKQTQ--------------------
-----------------------EEIKRN---------IMALRN------HLVSSTP--------ATDYFLQQK------
---------------DYFIIFLLILLQVIINFMFK-----------------------------
>MOUSE_OSBPL8
----------------------------MEAALADGEPDRSSLLGDSKDVLGPSTVVANSDEPQHLTPGKMSQRQGRDAN
PTPTRDLPQ-----------PSLSPASLHSQGFERGKEDIS------------QNKDDSSLSMSKSKSESKLYNGSEKDS
STSSK--------------------------------------------LTKKESLKVQKKNYREEKKRATKELLSTITD
PSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLIYKTQKNGQ--WVGTVLLNACEIIERPSKKDGFCFKLFHPLEQSIWAV
KGPKGEAVG-SITQPLPSSYLIIRATS---------------ESDGRCWMDALELALKCSSLLKRTMVREGKEHDLSISS
DSTH-----------VTLYGLLRANNLHSGDNFQLNDSEIERQHFKDQDLYSDKSDKEN---------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------DPEHDESDNEVLGKSEESDTDTSERQDDS
YIDP-------------------------------------EPVEPLKETTYMEQS-HEELGEAGEASQTETVSEENKSL
IWTLLKQVRPGMDLSRVVLPTFILEPRSFLDKLSDYYYHADFLSEAALE-------------------------------
------------------------------ENPYFRLKKVVKWYLSGFYKKPKGLKKPYNPILGETFRCLWIH---PRTN
SKTFYIAEQ---------------------VSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGN----------------
-SLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAILEFKLKPFLGSSDYVNQISGK
LKLGKEVLATLEGHWDSEVFINDKKT------DNSEIFWNPTPDIKQWRLIRHTVKFE----EQDDFES--EKLWQRVTK
AINA-KDQTEATQEKYVLEEAQRQAARDRKTKTQEWVCKLFELD------PLTGEWHYKFSDTRPWDPLN----DMIQFE
KDGVIQTKVKHR-TPMV------------------------------------SVPKMKHKPTRQ---------------
-QKKVVKGYSSPEPDIQDSSGSEAQSVKPSTR-RKKGIDLG------DIQSSIESIKQTQ--------------------
-----------------------EEIKRN---------IMALRN------HLLSSTP--------ATDYFLQQK------
---------------DYFVIFLLILLQVIINFIFK-----------------------------
>HORSE_OSBPL8
----------------------------MEAGLADGEPDRTSLLGDSKDVLGPSTVVANSDESQLLTPGKMSQRQGKEAY
PVPTRDSYQ-----------PSFSPASPHSQGFERTKEDIS------------QNKDESSLSMSKSKSESKLYNGSEKDS
STSSK--------------------------------------------LTKKESLKVQKKNYREEKKRATKELLSTITD
PSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLIYKTQKNGQ--WVGTVLLNACEIIERPSKKDGFCFKLFHPLEQSIWAV
KGPKGEAVG-SITQPLPSSYLIIRATS---------------ESDGRCWMDALELALKCSSLLKRTMIREGKEHDLSISS
ESTH-----------VTLYGLLRANNLHSGDNFQLNDSEIERQHFKDQDMYSDKSDKEN---------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------DQEHDESDNEVMGKSEESDTDTSERQDDS
YIEP-------------------------------------EPVEPLKETTYTEQS-HEELGEAGEASQTETVSEENKSL
IWTLLKQVRPGMDLSRVVLPTFILEPRSFLDKLSDYYYHADFLSEAALE-------------------------------
------------------------------ENPYFRLKKVVKWYLSGFYKKPKGLKKPYNPILGETFRCLWIH---PRTN
SKTFYIAEQ---------------------VSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGN----------------
-SLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAVLEFKLKPFLGSSDCVNQISGK
LKLGKEVLATLEGHWDSEVFINEKKT------DNSEVFWNPTPDIKQWRLIRHTVKFE----EQEDFES--EKLWQRVTR
AINA-KDQTEATQEKYVLEEAQRQAARDRKTKNEEWTCKLFELD------PLTGEWHYKFADTRPWDPLN----DMIQFE
KDGVIQTKVKHR-TPMV------------------------------------SVPKMKHKPTRQ---------------
-QKKVAKGYSSPEPDIQDSSGSEAQSLKPSTR-RKKGIELG------DIQNSIESIKQTQ--------------------
-----------------------EEIKRN---------IMALRN------HLVSSTP--------ATD-FLQQK------
---------------DYFIIFLLILLQVIINFMFK-----------------------------
>OPOSSUM_OSBPL8
------------------------MVLELSFNLDSDSWTTSLHVGDAKDVHGPSTLVTNNDDSHLLTSAKMNQRQGKEAY
LTPTKDLLQ-----------PSLSPGSAHSQGFERGKDDLS------------QNREETSHSMSKSKSESKLYNGSEKDI
SSSSK--------------------------------------------LTKKESLKVQKKNYREEKKRATKELLSTITD
PSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLIYKTQKNGQ--WVGTVLLNACELIERPSKKDGFCFKLFHPLEQSIWAV
KGPKGEAVG-SITQPLPSSYLIIRATS---------------ESDGRCWMDALELALKCSSLLKRTMIREGKEHDLSMSS
ENSH-----------VTFYGLLRANNLHSGDNFQLNDSEIERQHFKDQDMYSDKSDKEN---------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------DQEHDESDNEGIGKSEESDTDTSERQDDS
YIDP-------------------------------------EPTEVLKETTYTEQG-QEELGEAGEASQTETVSEENKSL
IWTLLKQVRPGMDLSRVVLPTFILEPRSFLDKLSDYYYHADFLSEASLE-------------------------------
------------------------------ENPYFRLKKVVKWYLSGFYKKPKGLKKPYNPILGETFRCLWVH---PRTN
SKTFYIAEQ---------------------VSHHPPISAFYISNRKDGFCLSGSILAKSKFYGN----------------
-SLSALLEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAVLEFKLKPFLGSSDCVNQISGK
LKLGKEVLATLEGHWDSEVIIHDKKT------DSSEVFWNPTSEIKQRRLIRHTVKFE----EQEPFES--EKLWQRVTR
AINV-KDQTEATQEKYVLEEAQRKAARERKGKNEEWICKLFELD------AATGEWHYRYSDTRPWDPLN----DLIQFE
KDGVIQTKVRHR-TPMV------------------------------------SVPKMKHKPSRQ---------------
-PKKAGKGYSSPELDIQDSSGSEAQVLKPSSR-RKKTVDLG------DLQCSIDCIKQTQ--------------------
-----------------------EEIKRS---------IVALRN------HLISSSS--------VTDTFLQPR------
---------------DYFIIFLLILLQIIINFMFK-----------------------------
>CHICKEN_OSBPL8
-------------------------MADIDVFDRRYAVESLLMLGRRLPHVQNFAVVTNSDESQLLTPGKMSQRQGKEAY
FTPTKELLQ-----------PSLSPATAHSHGFDKGKDEAS------------QSKEDTAHSMSKSKSESKLFNGSEKDI
SLSSS-------------------------------------------KLTKKESLKVQKKNYREEKKRATKELLSTITD
PSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLVYKTPKNGQ--WVGTVLLNACELIERPSKKDGFCFKLFHPLEQSIWAI
KGPKGEAVG-SITQPLPSSYLIIRAAS---------------ESDGRCWMDALELALKCSSLLKRTMIREGKEHDLNSSS
DSAH-----------VSLYGLLRANNLNSGDNLPLNDSEIERHHFKDQDMYSDKSDKEN---------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------DHEHDESDNDGLGKSEESDSDTSERQDDS
YVDP-------------------------------------EPID-IKETTYLEQS-HEELGEAGEAAQTEVVSEENKSL
IWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALE-------------------------------
------------------------------ENAYNRMKKVVKWYLSGFYKKPKGLKKPYNPILGETFRCMWIH---PRTN
SKTFYIAEQ---------------------VSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGN----------------
-SLSAILDGEGRLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCEKTGYSATIEFKLKPFLGNNDSVNQISGK
IKLGKEVLAILEGHWDSEVTIRDKKT------DVSETFWNPTSDIKQRRLPRYTVKFE----EQDDFES--EKLWQQVTK
AINN-KDQTEATQEKYVLEEAQRKSAKERKLKGEEWTCKLFDQD------SVTGEWHYRYADTRPWDPLN----DMIQFE
KDGTIQTKVRHR-TPMV------------------------------------TVPKIKRKPTG----------------
-QKKGECGFSSPEPDNQDSSGSEAQLTKHNTRIRKKGADLG------ELQSAIESIKETQ--------------------
-----------------------EDIKRD---------IMALRN------RVTSNSPP-------VDNQFLQLK------
---------------HYIFILLLVLLQLIINFLFK-----------------------------
>ANOLELIZARD_OSBPL8
--------------------------------------------------------------------------------
-------------------------------GFDRGKDDAS------------QGKDDSSQSMSKSKSESKLYNGSEKDI
AAASTTT-------------------------------------SSTTKLTKKESLKVQKKNYREEKKRATKELLSTITD
PSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLIYKTPKNGQ--WVGTVLLNACELIERPSKKDGFCFKLFHPLEQSIWAV
KGPKGEAVG-SITQPLPSSYLIIRAAS---------------ESDGRCWMDALELALKCSSLLKRTMIREGKEHEPN-LT
DGAH-----------VSFYGLLRANNVHSSESFPLNDSEIERHHFKDPDLYSDKSDREN---------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------DHDRDESDNDALG---ESDSDTSERQDDS
YIDP-------------------------------------EPDH-VKETTYIEEA-HEELGEAGEASQTETVSEENKSL
IWTLLKQVRPGMDLSKVVLPTFILETRSFLDKLSDYYYHADFLSEAALE-------------------------------
------------------------------ENAYNRMKQVVKWYLSGFYKKPKGLKKPYNPILGETFRCLWVH---PKTN
SKTFYIAEQ---------------------VSHHPPISAFYVSNRKDGFCLSGNILAKSRFYGN----------------
-SLSAILEGEGRLLFLNRGEEYIMNMPYAHCKGILYGTLTLELGGTVNIACEKTGYSAALEFKLKPFLGNNDNVNQIMGK
IKLGKEVLATLEGHWDSEVFIRDKKT------GISATFWNPTSEIRQCRLRRHTVKFE----EQSDFES--AKLWQHVTR
AINN-KDQAEATQEKYVLEEAQRKSAKERKAHDEEWICRLFEPD------PLTGEWIYRYADTRPWDPLN----DMIQFE
KGGAIQTKVKHR-TPMV------------------------------------SVAKIKRSAK-----------------
-SKKGECGFSSPEPDNQDSSGSEAQLT-HSTRVRKKTLDLI------ELQSAIESIRETQ--------------------
-----------------------EDIRRD---------ITALRT------RMSTSPPP-------QDNTFFQFK------
---------------HYVFILLMILLQLMINYLFK-----------------------------
>FROG_OSBPL8
-------------------------------MKEEGPLRRRSCAG-----VSPGTFLPRPDGRKLVRNASFGGYN-----
---------------------ELSPALP---GFDKGKDEVL------------QSKEDTSISMSKSKSESKLYNGSERDI
ASASS-------------------------------------------KLTKKESLKVQKKNYREEKKRATKELLSTITD
PSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLIYKTPKNGQ--WVGTVLLNACEIIERPSKKDGFCFKLFHPLEQSIWAV
KGPKGEAVG-SITQPLPSSYLIIRAAS---------------ESDGRCWMDALELALKCSSLLKRTMIREGKEHDLNSSA
DNSH-----------VGFYGLLRVNNLHSNENFQLNDSEIERHHFKDQDTYSDKSDKDN---------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------DHDHDESDNDGLGKSEESDSDTSERQDDS
FVDP-------------------------------------DPPELIKETTYVEEA-HEELGEAGEASQTETVSEEHKSL
IWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALE-------------------------------
------------------------------ENPYSRMKKVVKWYLSGFYKKPKGLKKPYNPILGETFRCLWIH---PRTS
SKTFYISEQ---------------------VSHHPPVSAFYVSNRKDGFCLSGSILAKSKFYGN----------------
-SLSALLEGEGRLTFLNRGEDYLMTMPYAHCKGILYGTMTLELGGSVTITCEKTSYSATLDFKLKPFLGSDDSVNQISGK
IKLGKEVLATLEGHWDSEVFIHDKKT------DVFETFWNPTLEIRHHRLIRCTVNQE----EQGEFES--ERLWRLVTL
AINN-KDQTEATQEKFVLEEAQRKAAKERKAKGEEWTCKLFEQD------PLTGEWHYKYADTRPWDPLN----DLIQFE
NDGVIQTKVRHR-TPMV------------------------------------CVPKLKHKASGQ---------------
-QKKGESGCSSPELDNQDSSGSEAHLLSHNNRVRKKGADHG------ELQSAIDSIKKTQ--------------------
-----------------------EEINRN---------IIALRN------RVSVNTSS-------TENSFLQQR------
---------------DYFIIFFLITLQIAVSYLFK-----------------------------
>MEDAKA_OSBPL8
---------------------------MDSSSESQTEPEKTLHNAESREHHAALAAVASGDEPGLLTPGRMSQRQVKEKD
REREKEAGLQTPSREHMASPSALSPGVSYSHGFERGKEDLLP-----------LPLKEDSNSISKSKSETKLYNGSDKDV
PGSGG-------------------------------------------KLTKKESLKVQKKNYREEKKRATKELLSTITD
PSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLIYKTHKNGQ--WVGTVLLNACELIERPSKKDGFCFKLFHPLEQSIWAV
KGPKGEAVG-SITQPLPSSHLIFRAAS---------------ESDGRCWMDALELALKCSSLLKRTMIREGKEDMSAVST
SGEHS----------INFYSLLRAHNLHG---FQFNDS----DHLKDPDLYSDKSDREG---------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------EPDHEESDPEGLE---ESDSDTSERQDDS
YIDL-------------------------------------DANEHLLETLYQEQS-HEELGEA----QTETVSEENKSL
IWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAAVE-------------------------------
------------------------------ENAYNRLKKVVKWYISGFYKKPKGLKKPYNPIIGETFRCLWLH---QNTN
SKTFYIAEQ---------------------VSHHPPVSAFYVSNRKDGFCLSGSILAKSKFYGN----------------
-SLSAILDGEARLTFLNRGEDYVMNMPYAHCKGILYGTMTLELGGQITIACEKTGYSAQLEFKLKPFLGSSDCVNQISGK
IKLGKEVLATLEGHWDSEIFINDKKT------GTMDTFWNPTSELRQSRLIRCTVPLE----EQSEFES--ERLWQQVTR
AINN-KDQT