>Homo_sapiens_GADD45A
--------------------------------------------------------------------------------
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--------------------------------------------------------MTLEEFSAG-EQKTE---------
------------------------------RMDKVGDALEEV-----------------------LSKALSQR------T
ITVG--------VYEAAKLLN----------------------------------------VDP---------------D
NVVLCLLAADEDDDRDVALQ---------------------------------------IHFTLIQAFCCEND-------
----------------------------------------------INILRVS-------------------NPGRLAEL
LLLETD--------------------------------------------------------------------AGPAAS
EGAEQPPDLHCVLVT--------NPHSSQWKDPALSQLICFCRESRYMDQWVPV-------INLPER-------------
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----------------------------------
>Pan_troglodytes_GADD45A
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--------------------------------------------------------MTLEEFSAG-EQKTE---------
------------------------------RMDKVGDALEEV-----------------------LSKALSQR------T
ITVG--------VYEAAKLLN----------------------------------------VDP---------------D
NVVLCLLAADEDDDRDVALQ---------------------------------------IHFTLIQAFCCEND-------
----------------------------------------------INILRVS-------------------NPGRLAEL
LLLETD--------------------------------------------------------------------AGPAAS
EGAEQPPDLHCVLVT--------NPHSSQWKDPALSQLICFCRESRYMDQWVPV-------INLPER-------------
--------------------------------------------------------------------------------
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----------------------------------
>Macaca_mulatta_GADD45A
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--------------------------------------------------------MTLEEFSAG-EQKTE---------
------------------------------RMDKVGDALEEV-----------------------LSKALSQR------T
ITVG--------VYEAAKLLN----------------------------------------VDP---------------D
NVVLCLLAADEDDDRDVALQ---------------------------------------IHFTLIQAFCCEND-------
----------------------------------------------INILRVS-------------------NPGRLAEL
LLLETD--------------------------------------------------------------------AGPAAT
EGAEQPPDLHCVLVT--------NPHSSQWKDPALSQLICFCRESRYMDQWVPV-------INLPER-------------
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>Mus_musculus_GADD45A
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--------------------------------------------------------MTLEEFSAA-EQKTE---------
------------------------------RMDTVGDALEEV-----------------------LSKARSQR------T
ITVG--------VYEAAKLLN----------------------------------------VDP---------------D
NVVLCLLAADEDDDRDVALQ---------------------------------------IHFTLIRAFCCEND-------
----------------------------------------------INILRVS-------------------NPGRLAEL
LLLEND--------------------------------------------------------------------AGPAES
GGAAQTPDLHCVLVT--------NPHSSQWKDPALSQLICFCRESRYMDQWVPV-------INLPER-------------
--------------------------------------------------------------------------------
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----------------------------------
>Oryctolagus_cuniculus_GADD45A
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--------------------------------------------------------MTLEEFSAG-EQKTE---------
------------------------------RMDKVGDALEEV-----------------------LSKALSQR------T
ITVG--------VYEAAKLLN----------------------------------------VDP---------------D
NVVLCLLAADEDDDRDVALQ---------------------------------------IHFTLIQAFCCEND-------
----------------------------------------------INILRVS-------------------NPGRLAKL
LLLETD--------------------------------------------------------------------ASPAAS
EGAAQPPDLHCVLVT--------NPHSSQWKDPALSQLICFCRESRYMDQWVPV-------INLPER-------------
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----------------------------------
>Canis_familiaris_GADD45A
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--------------------------------------------------------MTLEEFSAA-EQKSE---------
------------------------------RMDKVGDALEEV-----------------------LSKALSQR------T
ITVG--------VYEAAKLLN----------------------------------------VDP---------------D
NVVLCLLAADEDDDRDVALQ---------------------------------------IHFTLIQAFCCEND-------
----------------------------------------------IDILRVS-------------------NPGRLAEL
LLLEPH--------------------------------------------------------------------AGP-AS
EGAEQPPDLHCVLVT--------NPHSSQWKDPALSQLICFCRESRYMDQWVPV-------INLPER-------------
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----------------------------------
>Bos_taurus_GADD45A
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--------------------------------------------------------MTLEEFSAG-EQKTE---------
------------------------------RMDKVGDALEEV-----------------------LSKALSQR------T
ITVG--------VYEAAKLLN----------------------------------------VDP---------------D
NVVLCLLAADEDDDRDVALQ---------------------------------------IHFTLIQAFCCEND-------
----------------------------------------------IDILRVS-------------------NPGRLAEL
LLLETD--------------------------------------------------------------------AGPAAS
EGAEQPPDLHCVLVT--------NPHSSQWKDPALSQLICFCRESRYMDQWVPV-------INLPER-------------
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>Dasypus_novemcinctus_GADD45A
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--------------------------------------------------------MTLEEFSAG-EQKTE---------
------------------------------RMDKVGDALEEV-----------------------LSKALSQR------T
ITVG--------VYEAAKLLN----------------------------------------VDP---------------D
NVVLCLLAADEDDDRDVALQ---------------------------------------IHFTLIQAFCCEND-------
----------------------------------------------INILRVS-------------------NPGRLAEL
LLLETG--------------------------------------------------------------------TGPAAS
EGAEQPPDLHCVLVT--------NPHSSQWKDPALSQLICFCRESRYMDQWVPV-------INLPER-------------
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>Monodelphis_domestica_GADD45A
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--------------------------------------------------------MTLEEFAAG-EQKPE---------
------------------------------GMDKVGDALEEV-----------------------LSKALSQR------S
ITVG--------VYEAAKLLN----------------------------------------VDP---------------D
NVVLCLLAADEDDDRDVALQ---------------------------------------IHFTLIQAFCCEND-------
----------------------------------------------INILRVS-------------------NPGRLAEL
LLLGTGGP-----------------------------------------------------------------ASAAAAA
AAAEQPPDLHCVLVT--------NPHSSQWKDPALSQLICFCRESRYMDQWVPV-------INLPER-------------
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>Gallus_gallus_GADD45A
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--------------------------------------------------------MTLEELPGD-QRTAG---------
------------------------------RMEQAGDALEEV-----------------------LSKALSQR------S
LTLG--------VYEAAKLLN----------------------------------------VDP---------------D
NVVLCLLAADEEEEGDAALQ---------------------------------------IHFTLIQAFCCEND-------
----------------------------------------------INILRVS-------------------NPARLAQL
LLPDGG--------------------------------------------------------------------------
--PEPPTDLHCVLVT--------NPHASQWKDPALSQLMCFCRESRYMDQWVPV-------INLPER-------------
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>Anolis_carolinensis_GADD45A
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--------------------------------------------------------MTLEELAGE-HQALG---------
------------------------------SMEKVGDALEEV-----------------------LSKALTQR------S
ITVG--------VYEAAKLLN----------------------------------------VDP---------------D
NVVLCLLAADEEDNQDVALQ---------------------------------------IHFTLIQAFCCEND-------
----------------------------------------------INILRVS-------------------NPSRLAEL
LLLGAG-------------------------------------------------------------------------G
GGGEPPADLHCVLVT--------NPHASQWKDPALSQLICFCRESRYMDQWVPV-------INLPER-------------
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>Xenopus_tropicalis_GADD45A
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-----------------------------------------------------QYNMTLEEQLSG-DQSIG---------
------------------------------KMESVGNALEEV-----------------------LCKAKLQR------T
ITIG--------VYEAAKLLN----------------------------------------VDP---------------D
NVVLCLLATDDTYDQDIALQ---------------------------------------IHFTLIQAFCCEND-------
----------------------------------------------INILRVS-------------------NMSRLAEI
LG----------------------------------------------------------------------------GS
DKPGEPADLHCILIN--------SPHELQVKDPALKEVICYCKESRYLDQWVPV-------INLPER-------------
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>Danio_rerio_GADD45A_a
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--------------------------------------------------------MTFEEPCGD-NATE----------
------------------------------RMDSVEKALEEV-----------------------LTAALPQG------C
ITVG--------VYEAAKSLN----------------------------------------VDP---------------D
NVVLCLLATDEEDVKDVALQ---------------------------------------IHFTLIQAFCCEND-------
----------------------------------------------INILRVN-------------------NMRRLAEI
LEGMKP--------------------------------------------------------------------------
--GGESMDLHCVLVT--------NPQSSTWKDPALSKLNRFCRDSRGLDQWVPV-------INLPER-------------
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>Danio_rerio_GADD45A_b
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--------------------------------------------------------MTFEELNGD-YSIE----------
------------------------------RMNSVIKALEEV-----------------------LRSALPQG------C
ITVG--------VYEAAKSLN----------------------------------------VDP---------------D
NVVLCILATDDDDVKDVALQ---------------------------------------IHFTLIQAFCCEND-------
----------------------------------------------INILRVN-------------------NTRRLANI
LG-GAG--------------------------------------------------------------------------
MHGSEQMDLHCILVT--------VPHASTWKNPALGKVNRFCRESRCMDQWVPI-------INLPER-------------
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>Takifugu_rubripes_GADD45A_a
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--------------------------------------------------------MTFEELNGD-YSQES---------
------------------------------RMDSVAKALEEV-----------------------LTSALPQG------C
ITVG--------VYEAAKSLN----------------------------------------VDP---------------D
NVVLCILATDDEDVQDVALQ---------------------------------------IHFTLIQAFCCEND-------
----------------------------------------------INILRVN-------------------NTRRLAEI
LGGGSG-------------------------------------------------------------------------K
QSGGEPMDLHCVLVT--------SPHSTLWKDPALSKVNRFCRESRCMDQWVPI-------INLPER-------------
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>Tetraodon_nigroviridis_GADD45A_a
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--------------------------------------------------------MTFEELGAD-YSQE----------
------------------------------RMDSVARALEEV-----------------------LTSALPQG------C
ITVG--------VYEAAKSLN----------------------------------------VDP---------------D
NVVLCILATDDEDVQDVALQ---------------------------------------IHFTLIQAFCCEND-------
----------------------------------------------INILRVN-------------------NTRRLAEI
LGGGNG-------------------------------------------------------------------------K
QSGGEPLDLHCVLVT--------SPHSTSWKDPALGKVNRFCRESRCMDQWVPI-------INLPER-------------
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>Gasterosteus_aculeatus_GADD45A_a
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--------------------------------------------------------MTFEELSGD-FSQE----------
------------------------------RMDSVAKALEEV-----------------------LTSALPQG------S
ITIG--------VYEAAKSLN----------------------------------------VDP---------------D
NVVLCILATDDEDVKDVALQ---------------------------------------IHFTLIQAFCCEND-------
----------------------------------------------INILRVN-------------------NTQRLAEI
LGGAAGG------------------------------------------------------------------------K
QSGGEPMDLHCVLVT--------SPHSTSWKDPALSKVNRFCRESRCMDQWVPI-------INLPER-------------
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>Gasterosteus_aculeatus_GADD45A_b
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--------------------------------------------------------MTFEETSGD-NSSE----------
------------------------------RMESVAEALEEV-----------------------LSSAVPQG------C
TTVG--------VYEAAKSLN----------------------------------------ADP---------------D
NVVLCLLATDDE--EDVALQ---------------------------------------IHFTLIQAFCCEND-------
----------------------------------------------INILRVS-------------------NLQRLAEI
LGGGKA--------------------------------------------------------------------------
--GGEPTDLHCVLVT--------NPQSSLWKDPALSKVTRFCRESRCLDQWVPV-------INLPDR-------------
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>Oryzias_latipes_GADD45A_a
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-------------------------------MDSVAKALEEV-----------------------LTSALPQG------A
ITVG--------VYEAAKSLN----------------------------------------VDP---------------D
NVVLCVLATDEDDVKDVALQ---------------------------------------IHFTLIQAFCCEND-------
----------------------------------------------INILRVN-------------------STRRLGQI
LAGGGK--------------------------------------------------------------------------
QSGGEPLDLHCVLVS--------SPHSTSWKDPALSKVSRFCRESRGMDQWVPI-------IYLPER-------------
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>Oryzias_latipes_GADD45A_b
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--------------------------------------------------------MTLEEVVGSSSTDKK---------
-------------------------------METVSQALEEL-----------------------LVAAQRQD------C
LTVG--------VYESAKLMN----------------------------------------VDP---------------D
SVVLCLLATDEEDADDIALQ---------------------------------------IHFTLLQAFCCDND-------
----------------------------------------------INILRVS-------------------GMRRLAQL
LGEDTE------------------------------------------------------------------------NS
N-GNEPRDLHCILVT--------NPPVQPLQCQALQDVSSFCAESRCRNLWVPC-------LELKDR-------------
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>Homo_sapiens_GADD45B
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--------------------------------------------------------MTLEELVACDNAAQK---------
-------------------------------MQTVTAAVEEL-----------------------LVAAQRQD------R
LTVG--------VYESAKLMN----------------------------------------VDP---------------D
SVVLCLLAIDEEEEDDIALQ---------------------------------------IHFTLIQSFCCDND-------
----------------------------------------------INIVRVS-------------------GMQRLAQL
LGEPA-------------------------------------------------------------------------ET
QGTTEARDLHCLLVT--------NPHTDAWKSHGLVEVASYCEESRGNNQWVPY-------ISLQER-------------
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>Pan_troglodytes_GADD45B
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--------------------------------------------------------MTLEELVACDNAAQK---------
-------------------------------MQTVTAAVEEL-----------------------LVAAQRQD------R
LTVG--------VYESAKLMN----------------------------------------VDP---------------D
SVVLCLLAIDEEEEDDIALQ---------------------------------------IHFTLIQSFCCDND-------
----------------------------------------------INIVRVS-------------------GMQRLAQL
LGEPA-------------------------------------------------------------------------ET
QGTTEARDLHCLLVT--------NPHTDAWKSHGLVEVASYCEESRGNNQWVPY-------ISLQER-------------
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>Macaca_mulatta_GADD45B
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--------------------------------------------------------MTLEELVACDNAAQK---------
-------------------------------MQTVTAAVEEL-----------------------LVAAQRQD------R
LTVG--------VYESAKLMN----------------------------------------VDP---------------D
SVVLCLLAIDEEEEDDIALQ---------------------------------------IHFTLIQSFCCDND-------
----------------------------------------------INIMRVS-------------------GMQRLAQL
LGEPA-------------------------------------------------------------------------ET
QGTTEARDLHCLLVT--------NPHTDAWKSHGLVEVASYCEESRGNNQWVPY-------ISLQER-------------
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>Mus_musculus_GADD45B
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--------------------------------------------------------MTLEELVASDNAVQK---------
-------------------------------MQAVTAAVEQL-----------------------LVAAQRQD------R
LTVG--------VYEAAKLMN----------------------------------------VDP---------------D
SVVLCLLAIDEEEEDDIALQ---------------------------------------IHFTLIQSFCCDND-------
----------------------------------------------IDIVRVS-------------------GMQRLAQL
LGEPA-------------------------------------------------------------------------ET
LGTTEARDLHCLLVT--------NCHTDSWKSQGLVEVASYCEESRGNNQWVPY-------ISLEER-------------
--------------------------------------------------------------------------------
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----------------------------------
>Canis_familiaris_GADD45B
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--------------------------------------------------------MTLEELVACDNAAQK---------
-------------------------------MQTVSAAVEEL-----------------------LVAAQRQD------R
LTVG--------VYESAKLMN----------------------------------------VDP---------------D
SVVLCLLAIDEEEEDDIALQ---------------------------------------IHFTLIQSFCCDND-------
----------------------------------------------IDIVRVS-------------------GMQRLAQL
LGEPA-------------------------------------------------------------------------ET
QGTAEARDLHCLLVT--------NPHTDAWKSHGLVEVASYCEESRGNNQWVPY-------ISLQER-------------
--------------------------------------------------------------------------------
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----------------------------------
>Equus_caballus_GADD45B
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--------------------------------------------------------MTLEELVACDNAAQK---------
-------------------------------MQTVSAAVEEL-----------------------LVAAQRQD------R
LTVG--------VYESAKLMN----------------------------------------VDP---------------D
SVVLCLLAIDEEEEDDIALQ---------------------------------------IHFTLIQSFCCDND-------
----------------------------------------------INIVRVS-------------------GMQRLAQL
LGEPA-------------------------------------------------------------------------ET
QGTTEARDLHCLLVT--------NPHTDAWKSHGLVEVASYCEESRGNNQWVPY-------ISLQER-------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
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----------------------------------
>Pteropus_vampyrus_GADD45B
--------------------------------------------------------------------------------
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--------------------------------------------------------------------------------
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--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------MTLEELVACDNAAQK---------
-------------------------------MQTVSAAVEEL-----------------------LVAAQRQD------R
LTVG--------VYESAKLMN----------------------------------------VDP---------------D
SVVLCLLAIDEEEEGDIALQ---------------------------------------IHFTLIQSFCCDND-------
----------------------------------------------IDIVRVS-------------------GMQRLAQL
LGEPD-------------------------------------------------------------------------EA
QGTAEARDLHCLLVT--------NPHTDAWKSQGLVEVASYCEESRGNNQWVPY-------ISLQER-------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
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----------------------------------
>Monodelphis_domestica_GADD45B
--------------------------------------------------------------------------------
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--------------------------------------------------------------------------------
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--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------MTLEEVVACESAAQK---------
-------------------------------MQTVSNAVEEL-----------------------LVAAQRQD------R
LTVG--------VYESAKLMN----------------------------------------VDP---------------D
SVVLCLLAIDEDEEDDIALQ---------------------------------------IHFTLIQAFCCDND-------
----------------------------------------------IDIVRVS-------------------GMRRLAEL
LGEPG-------------------------------------------------------------------------PN
EESEETRDLHCLLVT--------NPHTDSWKSHGLVEVASYCEESRENNQWLPN-------ISLQER-------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
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----------------------------------
>Gallus_gallus_GADD45B
--------------------------------------------------------------------------------
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--------------------------------------------------------MDGQPQEGSDTEPRGRKAAPLLLP
L---------------------------LLLLLTTTARSSRT-----------------------LRPAAPGG------R
KEKG--------GLHRPHPHD----------------------------------------APPFH------PH--RDPD
SVVLCVLATDEEDEGDIALQ---------------------------------------IHFTLIQAFCCDND-------
----------------------------------------------IHIVRVA-------------------GMRRLAAV
LGEPA---------------------------------------------------------------------------
-PGAEPRDLHCLLVT--------MPHADAWQSHGLAEVANYCAESRDRNQWVPV-------VRLQER-------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
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--------------------------------------------------------------------------------
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--------------------------------------------------------------------------------
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----------------------------------
>Pelodiscus_sinensis_GADD45B
--------------------------------------------------------------------------------
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--------------------------------------------------------MTLEELVACDNTAQK---------
-------------------------------MRIVSGAVEQL-----------------------LVAAPRRG------R
LEF--------------SLDG----------------------------------------NDP---------------D
SVVLCLLATDEEDADDIALQ---------------------------------------IHFTLIQAFCCDND-------
----------------------------------------------IHILRVS-------------------GMQRLATV
LGENP---------------------------------------------------------------------------
QDNSEPRDLHCILVT--------NPHTDSWKSQGLEEVASYCEESRCNNQWVPC-------LSLLER-------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
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----------------------------------
>Danio_rerio_GADD45B_a
--------------------------------------------------------------------------------
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--------------------------------------------------------MTLEEVVGCNITDTK---------
-------------------------------MDTVSQALEEL-----------------------LVAAQRQD------C
LTVG--------VYESAKLMN----------------------------------------VDP---------------D
CVVLCILATDEEDLDDIALQ---------------------------------------IHFTLLQAFCCDND-------
----------------------------------------------INILRVS-------------------GLRRLAQV
LDEPAT------------------------------------------------------------------------VE
N--SEPRDFHCILVT--------NSQCQPLKCQALKDVGTYCEESRCKNQWIPY-------LSLQER-------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------