>Homo_sapiens_SH3RF1
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-------------------------------------------MDESALLDLLECP------------------------
--------------------VCLERLDASAKVLPCQHTFCKRCLLGIVGSRNELR-------------------------
-----------------------------CPECRTLV-GSGVEELPSNILLVRLLDGIKQR------PWKPGPGGGSGTN
CTNALRSQSSTVANCSSKDLQSSQGGQQPRVQSWSPPVRG----------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------IPQLPCAKALYN----------
----YEGKEPGDLKFS-----------------------KGDIIILRRQVDENWYHGEVNGIHGFFPTNFVQIIKPLP--
--------------------------------------------------------------------------------
-----------------------------------------------QPPPQCKALYDFE--------------------
--------------------------------------------------------------------------------
--------------------------------------VKDKEADKDCLPFAKDDVLTVIRRVDENWAEGMLADK-----
------------------------------------IGIFPISYVEFNSAA-------KQLIEWDKPPVPGVDAGEC---
--------------------------------------------------------------------------------
-----------------------------SSAA-AQSSTAPKHSDTKKNTKKRHSFTSLTMANKSSQASQ----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------NRHSMEISPPVLISSSNPTAAARISELSG-LSCSAPSQVHISTTGL
IVTPPPSSPVTTGPSFTFPSDVPYQAALG----TLNP---PLPPPPLLAATVLASTPPGA--------------------
------------TAAAAAAGMGPRPMAGSTDQIAHL--RPQTRP-----------------SVYVAIYPYTPRKEDELEL
RKGEMFLVFERCQDGWFKGTSMHTSKIGVFPGNYVAPVT----------------------RAVTNASQAKVPMSTAGQT
SRGVTMVSPST----AGGPAQKLQGNG---------------------------VAGSPSVVPAAVVSAAHIQTSPQAKV
LLHMT----------------------------------------------GQMTVNQAR----NAVRTVAAHNQER---
-----------PTAAVTPIQVQN-----AAGLSPASVGLSHHSLASPQPAPLMPGSATHTA-AISI-------SRASAPL
ACAAAAP-LTSPSITSASLEAEPSGRIVTV-----LPGLPTSPDSASSACGNSSATKPDKD-------------------
---------------SKKEKKGLLKLLSGASTKRKPRVS---PPA-SPTLEVELGSA------ELPLQGAVGPEL-----
----PPGG-GHGRAGSCPVDGDGPV-------------------------------------------------------
------------------------------------------------------------TTAVAGAALAQDAFHRKASS
LDSAVPIAPPPRQ---------------------------------ACSSLGPVLNESRPVVCER-------------HR
VVVSYPPQSEAELELKEGDIVFVHKKRED----GWFKG--TLQRN-----------------------------------
-----------------GKTG-----------------------------------LFPGSFVENI--------------
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>Mus_musculus_SH3RF1
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-------------------------------------------MDESALLDLLECP------------------------
--------------------VCLERLDASAKVLPCQHTFCKRCLLGIVGSRNELR-------------------------
-----------------------------CPECRTLV-GSGVDELPSNILLVRLLDGIKQR------PWKPGPGGGGGTT
CTNTLRAQGSTVVNCGSKDLQSSQCGQQPRVQAWSPPVRG----------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------IPQLPCAKALYN----------
----YEGKEPGDLKFS-----------------------KGDIIILRRQVDENWYHGEVSGVHGFFPTNFVQIIKPLP--
--------------------------------------------------------------------------------
-----------------------------------------------QPPPQCKALYDFE--------------------
--------------------------------------------------------------------------------
--------------------------------------VKDKEADKDCLPFAKDDVLTVIRRVDENWAEGMLADK-----
------------------------------------IGIFPISYVEFNSAA-------KQLIEWDKPPVPGVDTAEC---
--------------------------------------------------------------------------------
-----------------------------PSAT-AQSTSASKHPDTKKNTRKRHSFTSLTMANKSSQGSQ----------
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----------------------------------NRHSMEISPPVLISSSNPTAAARISELSG-LSCSAPSQVHISTTGL
IVTPPPSSPVTTGPAFTFPSDVPYQAALG----SMNP---PLPPPPLLAATVLASTPSGAT--AA---------------
---------VAAAAAAAAAGMGPRPVMGSSEQIAHL--RPQTRP-----------------SVYVAIYPYTPRKEDELEL
RKGEMFLVFERCQDGWYKGTSMHTSKIGVFPGNYVAPVT----------------------RAVTNASQAKVSMSTAGQA
SRGVTMVSPST----AGGPTQKPQGNG---------------------------VAGNPSVVPTAVVSAAHIQTSPQAKV
LLHMS----------------------------------------------GQMTVNQAR----NAVRTVAAHSQER---
-----------PTAAVTPIQVQN-----AACLGPASVGLPHHSLAS-QPLPPMAGPAAHGA-AVSI-------SRTNAPM
ACAAGAS-LASPNMTSAVLETEPSGRTVTI-----LPGLPTSPESAASACGNSSAGKPDKD-------------------
---------------SKKEKKGLLKLLSGASTKRKPRVS---PPA-SPTLDVELGAG------EAPLQGAVGPEL-----
----PLGG-SHGRVGSCPTDGDGPV-------------------------------------------------------
--------------------------------------------------------------AAGTAALAQDAFHRKTSS
LDSAVPIAPPPRQ---------------------------------ACSSLGPVMNEARPVVCER-------------HR
VVVSYPPQSEAELELKEGDIVFVHKKRED----GWFKG--TLQRN-----------------------------------
-----------------GKTG-----------------------------------LFPGSFVENI--------------
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>Pan_troglodytes_SH3RF1
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-------------------------------------------MDESALLDLLECP------------------------
--------------------VCLERLDASAKVLPCQHTFCKRCLLGIVGSRNELR-------------------------
-----------------------------CPECRTLV-GSGVEELPSNILLVRLLDGIKQR------PWKPGPGGGSGTN
CTNALRSQSSTVANCSSKDLQSSQGGQQPRVQAWSPPVRG----------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------IPQLPCAKALYN----------
----YEGKEPGDLKFS-----------------------KGDIIILRRQVDENWYHGEVNGIHGFFPTNFVQIIKPLP--
--------------------------------------------------------------------------------
-----------------------------------------------QPPPQCKALYDFE--------------------
--------------------------------------------------------------------------------
--------------------------------------VKDKEADKDCLPFAKDDVLTVIRRVDENWAEGMLADK-----
------------------------------------IGIFPISYVEFNSAA-------KQLIEWDKPPVPGVDAGEC---
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-----------------------------SSAA-AQSSTAPKHSDTKKNTKKRHSFTSLTMANKSSQASQ----------
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----------------------------------NRHSMEISPPVLISSSNPTAAARISELSG-LSCSAPSQVHISTTGL
IVTPPPSSPVTTGPSFTFPSDVPYQAALG----TLNP---PLPPPPLLAATVLASTPPGA--------------------
------------AAAAAAAGMGPRPMAGSTDQIAHL--RPQTRP-----------------SVYVAIYPYTPRKEDELEL
RKGEMFLVFERCQDGWFKGTSMHTSKIGVFPGNYVAPVT----------------------RAVTNASQAKVPMSTAGQT
SRGVTMVSPST----AGGPAQKLQGNG---------------------------VAGSPSVVPTAVVSAAHIQTSPQAKV
LLHMT----------------------------------------------GQMTVNQAR----NAVRTVAAHNQER---
-----------PTAAVTPIQVQN-----AAGLTPASVGLSHHSLASPQPAPLMPGSATHTA-AISI-------SRASAPL
ACAAAAP-LTSPSITSASLEAEPSGRIVTV-----LPGLPTSPDSASSACGNSSATKPDKD-------------------
---------------SKKEKKGLLKLLSGASTKRKPRVS---PPA-SPTLEVELGSA------ELPLQGAVGPEL-----
----PPGG-GHGRAGSCPVDGDGPV-------------------------------------------------------
------------------------------------------------------------TTAVAGAALAQDAFHRKASS
LDSAVPIAPPPRQ---------------------------------ACSSLGPVLNESRPVVCER-------------HR
VVVSYPPQSEAELELKEGDIVFVHKKRED----GWFKG--TLQRN-----------------------------------
-----------------GKTG-----------------------------------LFPGSFVENI--------------
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>Rattus_norvegicus_SH3RF1
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-------------------------------------------MDESALLDLLECP------------------------
--------------------VCLERLDASAKVLPCQHTFCKRCLLGIVGSRNELR-------------------------
-----------------------------CPECRTLV-GSGVDELPSNILLVRLLDGIKQR------PWKPGPGGGGSTT
CTNVLRAQGSTVVNCGSKDLQSPQCGQQPRVQAWSPPVRG----------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------IPQLPCAKALYN----------
----YEGKEPGDLKFS-----------------------KGDIIILRRQVDENWYHGEVNGVHGFFPTNFVQIIKPLP--
--------------------------------------------------------------------------------
-----------------------------------------------QPPPQCKALYDFE--------------------
--------------------------------------------------------------------------------
--------------------------------------VKDKEADKDCLPFAKDDVLTVIRRVDENWAEGMLADK-----
------------------------------------IGIFPISYVEFNSAA-------KQLIEWDKPPVPGVDTAEC---
--------------------------------------------------------------------------------
-----------------------------PSATAAQSSSASKHSDTKKNTRKRHSFTSLTMANKSSQASQ----------
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----------------------------------NRHSMEISPPVLISSSNPTAAARISELSG-LSCSAPSQVHISTTGL
IVTPPPSSPVTTGPSFTFPTDVPYQAALG----TMNP---PLPPPPLLATTVLASTPSGATA-AA---------------
---------VAAAAAAVAAGVGPRPAVGSTEQIAHL--RPQTRP-----------------SVYVAIYPYTPRKEDELEL
RKGEMFLVFERCQDGWYKGTSMHTSKIGVFPGNYVAPVT----------------------RAVTNASQAKVPMSTAGQA
SRGVTMVSPST----AGGPAQKPQGNG---------------------------VAGNPSVVPTAVVSAAHIQTSPQAKV
LLHMT----------------------------------------------GQMTVNQAR----NAVRTVAAHNQER---
-----------PTAAVTPIQVQN-----AACIGPASVGLPHHSLAS-QPLPPMVGPAAHIA-AVNI-------NRTSVPL
ACAAGASSLASPNMTTAALETEPSGRTVTI-----LPGLPTSPESAASACGNSSAVKPDKD-------------------
---------------SKKEKKGLLKLLSGASTKRKPRVS---PPA-SPTLDVELGSG------EVPLQGAVGPEL-----
----PLGG-VHGRVGSCPTDGDGPV-------------------------------------------------------
--------------------------------------------------------------AAGTAALAQDAFHRKTSS
LDSAVPIAPPPRQ---------------------------------ACSSLGPVMNEARPVVCER-------------HR
VVVSYPPQSEAELELKEGDIVFVHKKRED----GWFKG--TLQRN-----------------------------------
-----------------GKTG-----------------------------------LFPGSFVENI--------------
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>Monodelphis_domestica_SH3RF1
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-------------------------------------------MDESALLDLLECP------------------------
--------------------VCLERLDASAKVLPCQHTFCKRCLLGIVGSRNELR-------------------------
-----------------------------CPECRTLV-GCGVDELPSNILLVRLLDGIKQR------PRKPGS--GSGIN
CMGGLRAQGTSGVNCVSKDPQGSQGGQQ-RVQARSPPVRG----------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------VPQLPCAKALYN----------
----YEGKEPGDLNFS-----------------------KGDIIILRRQVDENWYHGEVNGIHGFFPTNFVQIIKPLP--
--------------------------------------------------------------------------------
-----------------------------------------------QPPPQCKALYDFE--------------------
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--------------------------------------VRDKEADKDCLPFAKDDVLTVIRRVDENWAEGMLSDK-----
------------------------------------IGIFPISYVEVTGPGR-----WDQLLMGNFPDPRPQDTVWV---
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-----------------------------KNNN-PKNYPLSPHDTSSNLAKERSLKNRVFHSIPSFSSLE----------
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----------------------------------NRHSMEISPPVLISSSNPTAAARISELTG-LSCSAPSQVHISTTGL
IVTPPPSSPVTTGPSFTFPSDVPYQAALG----NMNP---PLPPPPLLAATVNASTSPAAAS------------------
------------------SGVGQRP-AGSADQIAHL--RPQTRP-----------------SVYVAIYPYTPRKEDELEL
RKGEMFLVFERCQDGWFKGTSMHTSKIGVFPGNYVAPVT----------------------RTVTSASQSKVSMSTSGQT
GRVVTMVSPST----ASGSSQKLQGNG---------------------------VAGSPSVVPAVVASAAHIQTSPQAKV
LMAMT----------------------------------------------GQMTVNQAR----NAVRTVAVHNQER---
-----------PTAAVMPIQVQS-----SACFGPATVILPHQ-----QPQPSIPTSAAYVAAAVNL-------NRPAMPM
ACVAAGS-LNSPGIPATSLETELSGRAGTA-----LPGPPTSPESVLSAGGNSLATKSDNV-------------------
---------------SKKERKGLLKLLSGASTKRKPRAS---PPA-SPTLEVEQGPG------ELGLQGAVGPEL-----
----PVGG-SHGRAGSCPVDGDSPA-------------------------------------------------------
-----------------------------------------------------------------SVVLAQEALHRKTGS
LDAGVPIAPPPRQ---------------------------------PCSSLNSILNELRPVVCER-------------HR
VVVSYPPQSEAELELREGDIVFVHKKRED----GWFKG--TLQHN-----------------------------------
-----------------GKTG-----------------------------------LFPGSFVENI--------------
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>Gallus_gallus_SH3RF1
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-------------------------------------------MDESALLDLLECP------------------------
--------------------VCLERLDASAKVLPCQHTFCKRCLLGIVSSRNELR-------------------------
-----------------------------CPECRTLV-DCGVDELPSNILLVRLLDGIKQR------PRKPGTAGGTGG-
-ANTLRVPITTVANCGSKDLQSSQAGQQQRVQARSPPVRG----------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------VPQLPCAKALYN----------
----YEGKEPGDLKFS-----------------------KGDIIILRRQVDENWYHGEVNGIHGFFPTNFVQIIKPLP--
--------------------------------------------------------------------------------
-----------------------------------------------QPPPQCKALYDFE--------------------
--------------------------------------------------------------------------------
--------------------------------------VKDKEADKDCLPFAKDDVLTVIRRVDENWAEGMLADK-----
------------------------------------IGIFPISYVEFNTAA-------KQLIELDKPSGSAVDSGEG---
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-----------------------------TSGA-ALNNSVQKHTDTKKNTKKRHSFTSLTMSNKSSQSSQ----------
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----------------------------------NRHSMEISPPVLISSSNPTAAARISELTG-LSCSAPSQVHIGTTGL
IVTPPPSSPVTTGPSFTFPSEVTYQAALG----NMNP---PLPPPP-LSAAVVASASSGP--------------------
----------------QPAGVIQRSASGSADQMAHL--RPQTRP-----------------SVYIAIYPYTPRKEDELEL
RKGEMFLVFERCQDGWFKGTSMHTSKIGVFPGNYVAPAT----------------------RTVTSASQTKVPMSTAGQT
GRVVTVVSPST----ASGTSQKLQGNG---------------------------VAVNSSTVPTAVVSAAHIQTSPQTKV
LMHVT----------------------------------------------GQMTVNQAR----NAVRTVAVHNQDR---
-----------PTAAVTPIQAQS-----QTCLIPAAVIIPHHSVASQQLQSQLPNTAAYVT-AVNV-------NRSAIPL
ACAAASL--SSPSIAASSLEGDISGRTVNT-----HPVAPASPESSLAAGGSAAVSKTDKD-------------------
---------------VKKEKKGLLKLLSGASTKRKPRLS---PPS-SPTLEVEQAAT------ELALQGAVGPEL-----
----PSAG-GHSRAGICPTDCEVSG-------------------------------------------------------
--------------------------------------------------------------------PAQEMLQRKTSS
LDSAIPIAPPPRL---------------------------------PCSSLAPVLNESRPLVCER-------------YR
VVVSYPPQSEAELELKEGDIVFVHKKRED----GWFKG--TLQRN-----------------------------------
-----------------GKTG-----------------------------------LFPGSFVENV--------------
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>Danio_rerio_SH3RF1
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------------------------------MNEYAEKDCASVKMDESALLDLLECP------------------------
--------------------VCLERLDATAKVLPCQHTFCRRCLLGIVGSRGELR-------------------------
-----------------------------CPECRTLV-ESGVDELPSNILLVRLLDGIKQR------PRRTGSVHGTCAN
GSAVAGVR-AQGAGGSQRDPGPT-GGQSQRVQAKSTPVRG----------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------VPQLPCAKALYN----------
----YDGKEPGDLKFS-----------------------KGDIIILRRQVDENWYHGEMGGVHGFFPTNFVQVIKPLP--
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-----------------------------------------------QPPPQCKALYDFE--------------------
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--------------------------------------LKDKEADKDCLPFSKDDILTVIRRVDENWAEGMLGDK-----
------------------------------------IGIFPISYVEFNSAA-------RQLIELDKPSEGGGDSSEG---
--------------------------------------------------------------------------------
---------------------------PSSSSSGPQANGSQKAPGEKKNSKKRHSFTSLTMSHKPCLAPPP---------
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----------------------------------QRHSMEISGPVLISSSNPTAAARIGELSGGLSSSAPSQVHICTTGL
IVTPPPSSPVTTATVFTFPPETSYASIP----VDALP---PPPPPPPQSQSSVVG-------------------------
---------------AAALNAGQRPSPAAGDQ------SGRQRP-----------------TVYVAMFPYSPRKEDELEL
RKGEMFLVLERCQDGWFKGTSMHTGKIGVFPGNYMSPVS----------------------RTVSGSSQPKVPLTLCSQA
GRGVTIVSPSS-----ALGSMDLSKPLPVCP-----------------------NATPSCSLPAAVVTAAHLPTGQHPKV
LMHVT----------------------------------------------SQMTVNQAR----NAVRTAVSHSQDR---
-----------PTAAVTPIQS-H-----NPVA-----YLPSTAVVLQASPVLNS--------SSGC-------SSARVGV
ALGCAAASLTPPNVSAASLDTDAMRPVPMVA----LPVNAGSTKPLGAASNHGVACRLDKD-------------------
---------------CKREKKGLLKLLS---NKKKLRPS---PPS-SPTLEAEQSVSM------ELPQGAVGPEMA----
---LSGSAGHNGRIGACPMDSELSM-------------------------------------------------------
---------------------------------------------------------------SSSSSNTDAVTHR-SSP
QDNTAPIAPPPRQ---------------------------------PCSSLLSMQHDGRPIVCER-------------YR
VVVSYPPQSEAELELKEGDIVFVHKKRED----GWFKG--TLQRN-----------------------------------
-----------------GRTG-----------------------------------LFPGSFVDSI--------------
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>Takifugu_rubripes_SH3RF1
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-------------------------------------------MDESVLLDLLECP------------------------
--------------------VCLERLDASAKVLPCQHTFCRRCLQGILGSRGELR-------------------------
-----------------------------CPECRTLV-ECAVDELPSNILLVRLLDGIKQR------PRKAGPGAGVCTN
GTSGAVAR-SHNSG--TRDQGTP-GTQPQRAQAKSTLVRGCPDLPISSRSNRITGPDDVPPLYIQGLGTKSNWYWGTRSG
QHLFRPPNSLMLIQKPSLPQEKTQGCNVCYISYVADSERSNKDKLDFVPSCVLTIVSVWDLIWGFLLVCSAFGAPKSYRE
H--------------CVKDCLHLQTNLHNGADFGRCSAIKRGLVVKEALSWTPTMNGGIPQLPCAKALYN----------
----YDGKEPGDLKFS-----------------------KGDIVILRRQVDENWYHGEMGGVHGFFPTNFVQVIKPLP--
--------------------------------------------------------------------------------
-----------------------------------------------QPPPQCKALYDFE--------------------
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--------------------------------------LKDKEADKDCLPFSKDDILTVIRRVDENWAEGMLGDK-----
------------------------------------IGIFPISYVEFNTAA-------RQLIELDKPSDSNGDSGEG---
--------------------------------------------------------------------------------
------------------------------ASSGPLSNGAQRV-GEKKNSKKRHSFTSLTMSHKPMLAPPP---------
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----------------------------------QRHSMEISGPVLISSSNPTAAARIGEISGGLSCSAPSQVHICTTGL
IVTPPPSSPVTTATVFTFPSDSSYSSIP----VDALP---PPPPPPPQS--SVDG-------------------------
--------------AAYSLAAGQRPSASISDQ------SGRQRP-----------------TVYVAMFPYTPRKEDELEL
RKGEMFLVLERCQDGWFKGTSMHTGKIGVFPGNYMSPVS----------------------RTPPGSSQAKVHMSSCTPA
GRGITIVSPSS---ATIVPCPEFSKPLTCCS-----------------------SGVSAVSQPAAVVTAPQTATGQQPKV
PVHVN----------------------------------------------SQMTVNQAR----NAVRTAVCHSQDR---
-----------PTAAVTPILS-A-----ATVA-----YLPHLAVCSQTSPSP----------GQGC-------TRAG--V
AMGCAAASLTPPNVSAASLEGDALRPVPLL-----TVGSVNSS----ASNSTALACRLDKD-------------------
---------------NKKEKKSLLKLLS---NKKKSRSS---PPS-SPTLDAEQAAAAGGVAVGEALQGAAAPDAS----
---PPSGSVSCLEPEPAAVAPSASS-------------------------------------------------------
---------------------------------------------------------------SQCSSSALESSHRRSNP
LDGCAPIAPPPRQ---------------------------------PCSSLLSQHQDARPIICER-------------YR
VVVSYPPQSEAELELKEGDIVFVHRKRED----GWFKG--TLQRN-----------------------------------
-----------------GRTG-----------------------------------LFPGSFVDII--------------
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>Tetraodon_nigroviridis_SH3RF1
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------------------------------------------RMDESVLLDLLECP------------------------
--------------------VCLERLDASAKVLPCQHTFCRRCLQGILGSRGELR-------------------------
-----------------------------CPECRTLV-ECAVDELPSNILLVRLLDGIKQR------PRKAGPGAGVCTN
GTSGAVAR-SHSTG--SREQGPS-GTQPQRAQAKSTLVR-----------------------------------------
RYLIKIP-------------------------------------------------------------------------
-----------------------------------------------------------VHLPCLRSLVSS---------
----FQGKEPQALFVT-----------------------KPHPCGLSRQTDMNYFTGHKSPPHSSFPSASLSVLSPDV--
--------------------------------------------------------------------------------
-----------------------------------------------LFGDQCKALYDFE--------------------
--------------------------------------------------------------------------------
--------------------------------------LKDKEADKDCLPFSKDDILTVIRRVDENWAEGMLGDK-----
------------------------------------IGIFPISYVEFNTAA-------RQLIELDKPSDSNGDSGEG---
--------------------------------------------------------------------------------
------------------------------ASSGPLSNGAQRV-GEKKNSKKRHSFTSLTMSHKPMLAPPP---------
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----------------------------------QRHSMEISGPVLISSSNPTAAARIGEISGGLSCSAPSQVHICTTGL
IVTPPPSSPVTTATVFTFPSESSYSSIP----ADALP---PPPPPPPQS--SADGFLMCSQM------------------
---------SGKLRVGVCVHARAAPKAFVSPQPLSTLKSDGQHPQLRLS------------IMYVAMFPYTPRKEDELEL
RKGEMFLVLERCQDGWFKGTSMHTGKIGVFPGNYMSPVS----------------------RTPPGSSQAKVHLNPCTPA
GRGITIVSPSS---ATVAPCPEFQKALTCCS-----------------------SSVSVISQPAAVVTAPQMATGQQPKV
PVHVN----------------------------------------------SQMTVNQAR----NAVRTAVCHGQDR---
-----------PTAAVTPILS-A-----ATVT-----YLPHLAVCSQPPSSP----------AQSC-------TRVG--V
AMGCAAASLTPPNVSAASLEGDALR----------TAGPANSS----ASNSSAPACRLDKD-------------------
---------------TKKEKKSLLKLLS---NKKKSRSS---PPS-SPTLDAEQAAAA------EALQGAVAPDTF----
---PPSSSVSCLEPEPAVVVASASS-------------------------------------------------------
---------------------------------------------------------------SSSSSSAAESSHRRSSP
LDACAP-APPPRQ---------------------------------PCSSLLSQHQDARPIICER-------------YR
VVVSYPPQSEAELELKEGDIVFVHRKRED----GWFKG--TLQRN-----------------------------------
-----------------GRTG-----------------------------------LFPGSFVDII--------------
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>Gasterosteus_aculeatus_SH3RF1a
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------------------------------------------RMDESVLLDLLECP------------------------
--------------------VCLERLDASAKVLSCQHTFCRRCLQGILGSRGELR-------------------------
-----------------------------CPECRTLV-ECAVDELPSNILLVRLLDGIKQR------PRRAGPGPGVCTN
GTLGAVAR-AHGGG--ARDQGTP-GAQPQRAQAKGALVRA----------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------AAQLPCAKALYN----------
----YDGKEPGDLKFV-----------------------KGDVIILRRQVDENWYHGEMGGVHGFFPTNFVQVIKALP--
--------------------------------------------------------------------------------
-----------------------------------------------QPPPQCKALYDFE--------------------
--------------------------------------------------------------------------------
--------------------------------------LKDKEADKDCLPFSKDDILTVIRRVDENWAEGMLGDK-----
------------------------------------IGIFPISYVEFNSAA-------RQLIELDKPSDSSGDSGEG---
--------------------------------------------------------------------------------
------------------------------ASSGPQSNGAQRA-GEKKNSKKRHSFTSLTMSHKPMLAPPP---------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
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--------------------------------------------------------------------------------
----------------------------------QRHSMEISGPVLISSSNPTAAARIGEISGGLSCSAPSQVHICTTGL
IVTPPPSSPVTTATVFTFPSETSYTSTPV---VDDFS---RPQPPNYLSP-SVSS-------------------------
---------QAKCTAAPPLCHGSSHSPSGSPR------SGSRFP-----------------LNYVAMFPYTPRKEDELEL
RKGEMFLVLERCQDGWFKGTSMHTGKIGVFPGNYMSPVS----------------------RTASGSTQPKVPMSLCTQS
GRGVTVISPSP---TAVVPGPDINKPPAVCA-----------------------GAAPPSLQPATVA--AQTATGQQPKV
PLHVG----------------------------------------------SQMTVNQAR----NAVRTAAGHNHDR---
-----------PAPAGTQAQPPA-----APLA-----YLPHLAS---PSSGP----------AQCC-------SRAS--A
AMGCAAASLTPPNVSAASLDGDALRPAVVS-------VSGIDP----TSSSAALACRLDKD-------------------
---------------VKREKKSLLKLLSS--NKKKSRPS---PPS-SPTLEAEQAAAS------EALYAAVADAGL----
---FSPG-----EPKPAAVSSAASS-------------------------------------------------------
---------------------------------------------------------------AFSSSSAPDSSHRKVGP
LDGCAPIAPPPRQ---------------------------------PCSSLSSQQHDVRPIICER-------------YR
VVVSYPPQSEAELELKEGDVVFVHGKGED----GWFKG--TLQRN-----------------------------------
-----------------GRTG-----------------------------------LFPGSFVDSI--------------
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>Oryzias_latipes_SH3RF1
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-------------------------------------------MDESVLLDLLECP------------------------
--------------------VCLERLDASAKVLPCQHTFCRRCLQGILSSRGELR-------------------------
-----------------------------CPECRTLV-ECAVDDLPSNILLVRLLDGIKQR------PRKAGAGPAVCTN
GTPGATAR-AQGAG--TKDQNGP-GAPTQRAQAKSTAVRG----------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------VPQLPCAKALYN----------
----YDGKEPGDLKFS-----------------------KGD-----------------------------IVIKPLP--
--------------------------------------------------------------------------------
-----------------------------------------------QPPPQCKALYDFE--------------------
--------------------------------------------------------------------------------
--------------------------------------LKDKEADKDCLPFSKDDILTVIRRVDENWAEGMLGDK-----
------------------------------------IGIFPISYVEFNSAA-------RQLIESDKPSDSSGDCGEG---
--------------------------------------------------------------------------------
------------------------------ASSGPQSNGAQRA-GEKKNTKKRHSFTSLTMSHKPVLAPPP---------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
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--------------------------------------------------------------------------------
----------------------------------QRHSMEISGPVLISSSNPTAAARIGEISGGLSCSAPSQVHICTTGL
IVTPPPSSPVTTATVFTFPSETSYTSIP----LDILP---PPPPPPPQS--SVSG-------------------------
--------------AAYSLAAGQRPSPSTSDQ------SGRQRP-----------------TVYVAMFPYTPRKEDELEL
RKGEMFLVLERCQDGWFKGTSMHTGKIGVFPGNYMSPVS----------------------R---ASGSTKGPMSLCNQA
GRGVAILSPSSTPLGATAPGTDLNPTPPVCS-----------------------SAVPASTHPAAVVTAAQTATGQQPKA
PLHVS----------------------------------------------PQMTVNQAR----SAVRTAACHCQDR---
-----------PAAAVTPVQA-A-----APVT-----FLPHLVVCQQSSSNP----------AQGC-------ARAAA-A
AMGCAAASLTPPNVSATCLEGETPRPVPVCP----GSGAAVSA----SFAAAALACRADKD-------------------
---------------VKREKKSLLKLLSS--NKKRSRPS---PPS-SPTLESEQVAAG------ELLHGAVGPDTS----
---PPSSSVSCFEPEP------AAP-------------------------------------------------------
---------------------------------------------------------------SSSSHSFLEASQRKSSP
LD--PPIAPPPRQ---------------------------------PCSS-LSQQHDARSIICER-------------YR
VVVSYPPQSEAELELKEGDIVFVHRKRED----GWFKG--TLQRN-----------------------------------
-----------------GRTG-----------------------------------LFPGSFVDVM--------------
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>Homo_sapiens_SH3RF2
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-------------------------------------------MDDLTLLDLLECP------------------------
--------------------VCFEKLDVTAKVLPCQHTFCKPCLQRVFKAHKELR-------------------------
-----------------------------CPECRTPVFS-NIEALPANLLLVRLLDGVRSG-------QSSGRGGSFRRP
GTMTLQD--GRKSRTNPRRLQASPFRLVPNVRIHMDG-------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------VPRAKALCN----------
----YRGQNPGDLRFN-----------------------KGDIILLRRQLDENWYQGEINGISGNFPASSVEVIKQLP--
--------------------------------------------------------------------------------
-----------------------------------------------QPPPLCRALYNFDLR------------------
--------------------------------------------------------------------------------
--------------------------------------GKDKSENQDCLTFLKDDIITVISRVDENWAEGKLGDK-----
------------------------------------VGIFPILFVEPNLTAR-------HLLEKNKGRQSSRTKNLS---
--------------------------------------------------------------------------------
--------------------------LVSSSSRG---NTSTLRRGPGSRRKVPGQFSITTALNTLNRMVHS---------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------PSGRHMVEISTPVLISSSNPSVITQPMEKADVPSSCVGQ---VSTYHP
APVSPG--HSTAVVSLPGS-------------------------------------------------------------
------------------------QQHLSAN-------------------------------MFVALHSYSAHGPDELDL
QKGEGVRVLGKCQDGWLRGVSLVTGRVGIF-PNNYV-IPIFR-------------------------KTSSFPDSRSPGL
YTTWTLSTSSV-------------------------------------------SSQGSISEGDPRQSRPFKSVFVPTAI
VNPVR---------------------------------------------------------STAGPGTLGQGSLRK---
---------GRSSMRKNGSLQRPLQS-GIPTLVVGSLRRSPTMVLRPQQFQFYQPQGIPSSPSAVVV-------------
EMGSKPALTGEPALTCISRGSEAWIHSAASSLIMEDKEIPIKSEPLPKPPASAPPSILVKP-------------------
----------------ENSRNGIEKQVKTVRFQNYSPPP-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------TKHYTSHPTSGK
PEQPATLKASQPE-------------------------------------AASLGPEMTVLFAHR---------------
SGCHSGQQTDLRRKSALGKATT--LVSTA----SGTQT--VFPSK-----------------------------------
--------------------------------------------------------------------------------
-
>Mus_musculus_SH3RF2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------MDDLTLLDLLECP------------------------
--------------------VCFEKLDVTAKVLPCQHTFCKPCLQRIFKAHKELR-------------------------
-----------------------------CPECRTLVFC-SIEALPANLLLVRLLDGVRSG-------QSSWKGGSFRRP
RILTLQD--NRKAKSSPRSLQASPFRLVPSVRIHMDG-------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------VPRAKALCN----------
----YRGKNPGDLKFN-----------------------KGDVILLRRQLDENWYQGEINGVSGIFPASSVEVIKQLP--
--------------------------------------------------------------------------------
-----------------------------------------------QPPPLCRALYNFDLR------------------
--------------------------------------------------------------------------------
--------------------------------------DKDKSENQDCLTFLKDDVITVISRVDENWAEGKLGDK-----
------------------------------------VGIFPILFVEPNVSAR-------HLLE-NKGHQLSRTRHLS---
--------------------------------------------------------------------------------
--------------------------LMSSPSRGKATNTSSLRKSPGSRRKGSGQFSMTTALNTLNRTVHS---------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------PEGHQMVEISTPMLISSNSPSVLTQHGDKADFPTSSTGQ---VSSSQP
APASPG--HSTAMVSVPSS-------------------------------------------------------------
------------------------QQHLSNN-------------------------------MFVALHTYSAHRPEELDL
QKGEGIRVLGKYQDGWLKGLSLLTGRTGIF-PSDYV-IPVFSSTAR---------------------KTSSFPDSRSPTV
CTTWALSTSSV-------------------------------------------SSQGSFAEGDPRQSGPFKSVFVPTAV
VNPSR---------------------------------------------------------STPGPGSSGQGSLRK---
---------VRSSMRKNGSLQRPVQS-GIPTFMVGSLRCSPTMVIRPQRFQFYPPQGMTPSPTPIMV-------------
EMGSKSIYTGEPALTCINRGSKTRIHSAGNSIIMEGKETPIKSEPPPKPPASAPPSILVKP-------------------
----------------ENSKNGTEKQVKTVRFQNYSPPP-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------TKHSASSPTSGK
HDHPATLKGSQHE-------------------------------------AVSSGGEMTILFAHR---------------
SGCHSGQQTDLRRKSAFGKTMP--LLSTA----SATQT--LFPSK-----------------------------------
--------------------------------------------------------------------------------
-
>Pan_troglodytes_SH3RF2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------MDDLTLLDLLECP------------------------
--------------------VCFEKLDVTAKVLPCQHTFCKPCLQRVFKAHKELR-------------------------
-----------------------------CPECRTPVFS-NIEALPANLLLVRLLDGVRSG-------QSSGRGGSFRRP
GTMTLQD--GRKSRTNPRRLQASPFRLVPNVRIHMDG-------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------VPRAKALCN----------
----YRGQNPGDLRFN-----------------------KGDIILLRRQLDENWYQGEINGISGNFPASSVEVIKQLP--
--------------------------------------------------------------------------------
-----------------------------------------------QPPPLCRALYNFDLR------------------
--------------------------------------------------------------------------------
--------------------------------------GKDKSENQDCLTFLKDDIITVISRVDENWAEGKLGDK-----
------------------------------------VGIFPILFVEPNLTAR-------HLLEKNKGRQSSRTKNLS---
--------------------------------------------------------------------------------
--------------------------LVSSSSRG---NTSTLRRGPGSRRKVPGQFSITTALNTLNRMVHS---------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------PSGRHMVEISTPVLISSSNPSVITQPMEKADVPSSCVGQ---VSTYHP
APVSPG--HSTAVVSLPGS-------------------------------------------------------------
------------------------QQHLSAN-------------------------------MFVALHSYSAHGPDELDL
QKGEGVRVLGKCQDGWLRGVSLVTGRVGIF-PNNYV-IPIFR-------------------------KTSSFPDSRSPGL
YTTWTLSTSSV-------------------------------------------SSQGSISEGDPQQSRPFKSVFVPTAI
VNPVR---------------------------------------------------------STAGPGTLGQGSLRK---
---------GRSSMRKNGSLQRPLQS-GIPTLVVGSLRRSPTMVVRPQQFQFYQPQGIPSSPSAMVV-------------
EMGSKPALTGEPALTCISRGSEARIHSAASSLIMEDKEKTIKSEPLPKPPASAPPSILVKP-------------------
----------------ENSRNGIEKQVKTVRFQNYSPPP-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------TKHYTSHPTSGK
PEQPATLKASQPE-------------------------------------AASLGPEMTVLFAHR---------------
SGCHSGQQTDLRRKSALGKATT--LVSTA----SGTQT--VFPSK-----------------------------------
--------------------------------------------------------------------------------
-
>Rattus_norvegicus_SH3RF2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------MDDLTLLDLLECP------------------------
--------------------VCFEKLDVTAKVLPCQHTFCKPCLQRIFKAHKELR-------------------------
-----------------------------CPECRTLVFC-SIEALPANLLLVRLLDGVRSG-------HNSWRGGSFRRP
RILTLQD--NRKAKSSPRSLQASPFRLGPTVRIHMDG-------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------VPRAKALCN----------
----YRGKNPGDLKFN-----------------------KGDVILLQRQLDENWYQGEINGVSGFFPASSVEVIKQLP--
--------------------------------------------------------------------------------
-----------------------------------------------QPPPLCRALYNFDLR------------------
--------------------------------------------------------------------------------
--------------------------------------DKDKSENQDCLTFLKDDVITVISRVDENWAEGKLGDK-----
------------------------------------VGIFPILFVEPNLSAR-------HLLEKSKGHQLSRTKHLS---
--------------------------------------------------------------------------------
--------------------------LMSSPSRGKATNTSTLRKSPGSRRKGSGQFAMTTALNTLNRMVHS---------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------PEGHQMVEISTPVLISSTSPSMLTQHGDRADFPASSAGQ---VSTSHP
APASPG--HSTAMVSVPSS-------------------------------------------------------------
------------------------QQHLSTN-------------------------------MFVALHTYSAQGPEELDL
KKGEGIRVLGKNQDGWLRGVSLVTGRTGIF-PSDYV-IPVFSSTAR---------------------KTSSFPDSRHPTV
CTTWALSTSSV-------------------------------------------SSQGSFSEGDPRQSGPFRSVFVPTAV
N-PPR---------------------------------------------------------STSGPGTSGQGSLRK---
---------VRSSMRKNGSLQRPVQS-GIPTFMVGSLRCSPAMVIRPQKFQFYQPQGMTPSPTPIMV-------------
EIGSKSISTGEPALTCINRGGKTRTHSAGNSIIMEGKETPIKSEPPPKPPASAPPSILVKP-------------------
----------------ENSKNGIEKQVKTVRFQNYSPPP-----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------TKHSASGPTSGK
HEQPATLKGSQPE-------------------------------------AVSSEGEMTILFAHR---------------
SGCHSGQQTDLRRKSAFSKTTP--PVSTA----SVSQT--LFPSK-----------------------------------
--------------------------------------------------------------------------------
-
>Bos_taurus_SH3RF2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------MDDVTLLDLLECP------------------------
--------------------VCLEKLDVTAKVLPCQHTFCKPCLQRIFKAHKELR-------------------------
-----------------------------CPECRTLVFC-SIEALPANLLLVRLLDGVRAG-------QSSGRGGSFRRP
GVLTPQD--GRRSRTHPRGPQCSPFRLVPNVRIHMDG-------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------VPRAKALCN----------
----YRGQNPGDLRFN-----------------------KGDVILLRRQLDENWYQGEINGVSGVFPASSVEVIKQLP--
--------------------------------------------------------------------------------
-----------------------------------------------QPPPLCRALYNFDLR------------------
--------------------------------------------------------------------------------
--------------------------------------DKDRSENQDCLTFLKDDIITVISRVDENWAEGKLGDK-----
------------------------------------VGIFPILFVEPNLTAR-------HLLEKNKGRPSSRTKNLS---
--------------------------------------------------------------------------------
--------------------------LVSSPSRGKATSTPTLRRGPGSRRKGPGQFSITTALNTLNRMVHS---------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------PSGRHMVEISTPVLISSSNPSVITQHVEKADASPSSVGQ---VSTYHP
APASPG--HSTAIVSLPGS-------------------------------------------------------------
------------------------QQHLSAN-------------------------------MFVALHSYSAHGPDELDL
QKGEGVRVLGKYQDGWLRGVSLVTGRVGIF-PNNYV-IPIFR-------------------------KTSSVPDSRSPGL
YTAWTLSTSSV-------------------------------------------SSQGSISESDPRQSQPFKSVFVPTAI
VNPVR---------------------------------------------------------SPASLG