>HUMAN_NFE2
--------------------------------------------------------------------------------
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-------------------------------------------------------------------------MSPCPPQ
QSRNRVIQLSTSELGEMELT-WQEIMSITELQGLNAPSEPSFEPQAP-------------APYLGPPPPT----------
----------------TYCPCSIHPDSGFPLPPPPYELPASTSHVPDPPYSYG---------------------------
--------------------------------------------------------------------------------
---NMAIPVSKPLSLSGLLSEPLQDPLALLDIGLPAGPP----KPQEDP-------------------------------
--------------------------------------ESDSG----------LSLNYSDAESLELEGTEAGRRRSEYVE
MYPVEY---------------------------PYSLMPNSLAHSNYTLP------------AAETPLALEPS-------
--------------------------------------------------------------------------SGPVRA
KPTARGEAG---------------------------------------------SRDERRALAMKIPFPTDKIVNLPVDD
FNELLARYPLTESQLALVRDIRRRGKNKVAAQNCRKRKLETIVQLERELERLTNERERLLRARGEADRTLEVMRQQLTEL
YRDIFQHLRDESGNSYSPEEYALQQAADGTIFLVPRG-------------------------------------------
------------------------------------------------TKMEATD-------------------------
-------------------
>MOUSE_NFE2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------MPPCPPQ
QNRNRLSQLPVGELGEMELT-WQEIMSITELQGLNVPSETSFEPQAP-------------TPYPGPLPPP----------
----------------TYCPCSIHPDAGFSLPPPSYELPASTPHVPELPYSYG---------------------------
--------------------------------------------------------------------------------
---NVAIPVSKPLTLSGLLNEPLPDHLALLDIGLPVGQP----KPQEDP-------------------------------
--------------------------------------ESDSG----------LSLNYSDAESLELEGMEAGRRRSEYAD
MYPVEY---------------------------PYSLMPNSLAHPNYTLP------------PTETPLALESS-------
--------------------------------------------------------------------------SGPVRA
KPAVRGEAG---------------------------------------------SRDERRALAMKIPFPTDKIVNLPVDD
FNELLAQYPLTESQLALVRDIRRRGKNKVAAQNCRKRKLETIVQLERELERLSSERERLLRARGEADRTLEVMRQQLAEL
YHDIFQHLRDESGNSYSPEEYVLQQAADGAIFLVPRG-------------------------------------------
------------------------------------------------TKMEATD-------------------------
-------------------
>RAT_NFE2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------MPPCPPQ
PNRNRLPQLPTGELGEMELT-WQEIMSITELQGLNVPSEPSFEPQAP-------------TPYPGPLPPP----------
----------------TYCPCSIHPDAGFTLPPPPYELPASTPHAPDLPYSYG---------------------------
--------------------------------------------------------------------------------
---NIAIPVSKPLTLSGLLNEPLPDPLALLDIGLPVGQP----KPQEDP-------------------------------
--------------------------------------ESDSG----------LSLNYSDAESLELEGTEAGRRRSEYVD
MYPVEY---------------------------PYSLMPNSLAHPNYTLP------------PTETPLVLESS-------
--------------------------------------------------------------------------SGPVRA
KPAVRGEAG---------------------------------------------SRDERRALAMKIPFPTDKIVNLPVDD
FNELLAQYPLTESQLALVRDIRRRGKNKVAAQNCRKRKLETIVQLERELERLGSERERLLRARGEADRTLEVMRQQLTEL
YHDIFQHLRDESGNSYSPEEYVLQQAADGAIFLVPRG-------------------------------------------
------------------------------------------------TKMEATD-------------------------
-------------------
>DOG_NFE2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------MPPCPPQ
QSRDRGTQLPTPELGEMELT-WQEIMSITELQGLNAPSEPSFETPAP-------------APYPGPPPPP----------
----------------TYCPCSIHPDAGFPLPPTPYELPAAASHVPDPSYSYG---------------------------
--------------------------------------------------------------------------------
---NMAIPVSKPLTLSGLLSETLPDPLALLDIGLPAGPP----KPQEDP-------------------------------
--------------------------------------ESDSG----------LSLNYSDAESLELEGTEAGRRRSEYVE
MYPVEY---------------------------PYSLMPNSLAHPNYALP------------PAETPLALEPS-------
--------------------------------------------------------------------------AGPVRA
KSTARGEAG---------------------------------------------SRDERRALAMKIPFPTDKIVNLPVDD
FNELLARYPLTESQLALVRDIRRRGKNKVAAQNCRKRKLETIVQLERELERLGNERERLLRARGEADRTLEVMRQQLTEL
YCDIFQHLRDEAGNSYSPEEYALQQAADGAIFLVPRG-------------------------------------------
------------------------------------------------TKVEAED-------------------------
-------------------
>HORSE_NFE2
--------------------------------------------------------------------------------
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--------------------------------------------------------------------------------
-----------------------------------------------MEPNQKAQVFLQILSLLPLLKWENLGDRKIVAS
TLSAQQWPGGGARPSPALRGSRDPHPGGVSPGPASPETAPGASSLSSLCSDPATGCWGCLGFGGPWTRPWPSRMPPCPPQ
QSRNRVTQLPTPELGEMELT-WQEIMSITELQGLNAPTEPSFEPPAP-------------APYPGPPPPS----------
----------------TYCPCSIHPDAGFPLPPPPYELPAPTSHVQDPPYSYC---------------------------
--------------------------------------------------------------------------------
---NMAIPVSKPLTLSGLLSEPLPDPLALLDIGLPAGPP----KPQEDP-------------------------------
--------------------------------------ESDSG----------LSLNYSDAESLELEGTEVGRRRGEYVE
MYPVEY---------------------------PYSIMPNSLAHPNYALP------------PAETPLALEPS-------
--------------------------------------------------------------------------SGPVRA
KPTARGEVG---------------------------------------------SRDERRALAMKIPFPTDKIVNLPVDD
FNELLARYPLTESQLALVRDIRRRGKNKVAAQNCRKRKLETIVQLERELERLGSERERLLRARGEADRTLEVMRQQLTEL
YRDIFQHLRDEAGNNYSPEEYVLQQAADGAIFLVPRG-------------------------------------------
------------------------------------------------PKVEATD-------------------------
-------------------
>PLATYPUS_NFE2
--------------------------------------------------------------------------------
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--------------------------------------------------------------------------------
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-------------------------------------------------------------------FPTDKIVNLPVDD
FNELLGRYPLSESQLALVRDIRRRGKNKVAAQNCRKRKLETLVQLERELAELSTRRERLLRARGEAGRTLGLLRQQLGDL
YRDVFARLQDEEGNGYSPDEYVLQQAADGTVFLAPRG-------------------------------------------
------------------------------------------------TPAQED--------------------------
-------------------
>Fugu_NFE2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------MTANFPGARPHGTLHDCEMDVTWQEL
MAITELQ-FDAPAEGSFEAMQYQSMEAMAPMGGYGMPSSHSALPPAP-------------SHRLGGNTEA----------
----------------MYSHAETQLSQRVLPAPSHPQLSVMAPGEQNTFPSTGQVQRGPSAH------------------
--------------------------------------------------------------------------------
--FSQGPSQHMLWSVHEQALHARSADDLESDSGLSLGSS----PSLASP-------------------------------
--------------------------------------DYPGGSGAPCYQSAEMGPTYSDGEAD--MTERVQTARIHYSM
EYQSQC---------------------------HTYVQSAGHPSNFATQP------------VVAHAQTHWST-------
----------------------------------------------------------------KEPDQTAAVNSLYVDP
GVSSRGSPHPSSFPKPQASVS----------------------------T--PLSRDERRAKALKIPFPMDQIINLPVDD
FNELLTQYTLTDSQLALVRDIRRRGKNKVAAQNCRKRKLESIIHLETELNQLQTQRELLSKQRFEFTRSLAFIKRRLSDL
YSQVFSRLRDEDGQPYSVEDYALQQTPDGKVYLVPHS-------------------------------------------
------------------------------------------------MKT-----------------------------
-------------------
>STICKLEBACK_NFE2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------MDVAWQEL
MAIPELQEFEVSSAGSYETAQYQTMEPMVPVGGYEMAQSHPEALPAACALSTADAYDG-CFHRLGDNAGA----------
----------------MYGHADSQHFQRMLPASGHAQPSHVALREQMNASGAGQGHRRAHAG------------------
--------------------------------------------------------------------------------
--LSQDPRRHMLWTTHGHGAHVLPADEIESDSGLSLGSS----PPLASP-------------------------------
--------------------------------------DNPVG-GAPGYQRVDVGVTYSDGEPDS-MAEQARRASAHYSM
DYQSQS---------------------------YSYLHPGGHP-AYSTEP------------NLSHPAPIALSR------
--------------------------------------------------------------PVKPPGQNCALGHLSIDM
GASSRGSSQYNVYAKPQGSIS----------------------------TPAPLSRDERRAMSLKIPFPMEKIVNLPVDD
FNELLTQYTLTDHQLALVRDIRRRGKNKVAAQNCRKRKLESIIHLEKELNQLQAQREHLARERVEFQRSLTFIKCHLTDL
YSQVFSHLRDEEGQPFSIDEYALQQTLDGKIYLVPNA-------------------------------------------
------------------------------------------------TMQKR---------------------------
-------------------
>TETRAODON_NFE2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------MDVAWQEL
MAITELQ-FDAPTEGSFEAMQYQSMEAMTPMEGYGMGSSQSVPPASGESYNGCYHNEVPLGHRSGNNMDA----------
----------------MYSHTETQLSQRVLPAPFHAQLTVIAPGEQNSFP-------GP---------------------
--------------------------------------------------------------------------------
---SQGLSQNMLWSMHERALHTRSADDLESDSGLSLGSS----PSLASP-------------------------------
--------------------------------------DYPGGSSAPCYQSADVGPTYSDGEAD--MTERVQSAHIHYSM
EYQSQC---------------------------HTYVQSARQPSHFSTQP------------IASHTQTQWSS-------
----------------------------------------------------------------KDPDQAGAVNSLHVDP
RVPSRGSPHPNSFTKPQTSMP----------------------------T--PLSRDERKAKALNIPFPMDQIINLPVDD
FNELLTQYTLTDTQLALVRDIRRRGKNKVAAQNCRKRKLESIIHLEAELNQLKTQKEILSKQRFEFNRSLAFIKRRLSEL
YSQVFSRLRDEDGQPYSVKDYSLQQTPDGKVYLVPHS-------------------------------------------
------------------------------------------------MKTWGK--------------------------
-------------------
>HUMAN_NFE2L1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------MLSLKKYLTEGLLQFTILLSLIGVRVDVDTYLTSQL
PPLR-----------EIILGPSSAYTQTQFHNLRNTLDGYGIHPKSIDLDNYFT-----ARRLLSQVRALDRFQVPTTEV
NAWLVHRDPEGSVSGS-QPNSGLALESSSGLQDVTGPDNG------VRESETEQGFGEDLEDLGAVAPP-----------
-----------------VSGDLTKEDIDLIDILWRQDIDLGAGREVFDYSHRQKEQDVEKEL-----RDGGE-QDTWAGE
GAEALARN--LLVDGETGESFPAQVPSGEDQTALSLEECLRLLEATCPFGENAEF-PADISSITEAVPSESEPPALQNNL
LSPLLTGTESPFDLEQQWQDLMSIMEMQAMEVN-TSASEILYSAPPGDP----------LSTNYSLAP-NTPINQNVSLH
QASLGGCSQDF-LLFSPEVE---SLPVASSSTLLPLAPSNSTSLNSTFGSTNLTGLFFPPQLN-GTANDTAGPELPDPLG
GLLDEAMLDE----ISLMDLAIEEGFNPVQASQLEEEFDSDSGLSLDSSH-------SP---SSLSSSEGSSSSSSSSSS
SSSSASSSASSSFSEEGAVGYSSDSETLDLEEAEGAVG-YQPEYSKFCR-MSYQDPAQLSCLPYLEHVGHNHTYNMAPSA
LDSADLPPPSALKKGSKEKQA--------------------------DFLDKQMSRDEHRARAMKIPFTNDKIINLPVEE
FNELLSKYQLSEAQLSLIRDIRRRGKNKMAAQNCRKRKLDTILNLERDVEDLQRDKARLLREKVEFLRSLRQMKQKVQSL
YQEVFGRLRDENGRPYSPSQYALQYAGDGSVLLIPRT-------------------------------------------
------------------------------------------------MAD-QQARRQERKPKDRRK-------------
-------------------
>MOUSE_NFE2L1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------MLSLKKYLTEGLLQFTILLSLIGVRVDVDTYLTSQL
PPLR-----------EIILGPSSAYTQTQFHNLRNTLDGYGIHPKSIDLDNYFT-----ARRLLSQVRALDRFQVPTTEV
NAWLVHRDPEGSVSGS-QPNSGLALESSSGLQDVTGPDNG------VRESETEQGFGEDLEDLGAVAPP-----------
-----------------VSGDLTKEDIDLIDILWRQDIDLGAGREVFDYSHRQKEQDVDKEL-----QDGREREDTWSGE
GAEALARD--LLVDGETGESFPAQFP-------------------------------ADVSSIPEAVPSESESPALQNSL
LSPLLTGTESPFDLEQQWQDLMSIMEMQAMEVN-TSASEILYNAPPGDP----------LSTNYSLAP-NTPINQNVSLH
QASLGGCSQDF-SLFSPEVE---SLPVASSSTLLPLVPSNSTSLNSTFGSTNLAGLFFPSQLN-GTANDTSGPELPDPLG
GLLDEAMLDE----ISLMDLAIEEGFNPVQASQLEEEFDSDSGLSLDSSH-------SP---SSLSSSEGSSSSSSSSSS
SS--ASSSASSSFSEEGAVGYSSDSETLDLEEAEGAVG-YQPEYSKFCR-MSYQDPSQLSCLPYLEHVGHNHTYNMAPSA
LDSADLPPPSTLKKGSKEKQA--------------------------DFLDKQMSRDEHRARAMKIPFTNDKIINLPVEE
FNELLSKYQLSEAQLSLIRDIRRRGKNKMAAQNCRKRKLDTILNLERDVEDLQRDKARLLREKVEFLRSLRQMKQKVQSL
YQEVFGRLRDEHGRPYSPSQYALQYAGDGSVLLIPRT-------------------------------------------
------------------------------------------------MAD-QQARRQERKPKDRRK-------------
-------------------
>RAT_NFE2L1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
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--------------------------------------------------------------------------------
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--------------------------------------------------------------------------------
-----------------------------MEVN-TSASEILYSAPPGDP----------LTTNYSLAP-NTPINQNVSLH
QASLGGCSQDF-SLFSPEVE---SLPVASSSTLLPLVPSNSTSLNSTFGSTNLAGLFFPSQLN-GTANDTSGPELPDPLG
GLLDEAMLDE----ISLMDLAIEEGFNPGQASQLEEEFDSDSGLSLDSSH-------SP---SSLSSSEGSSSSSSSSSS
----ASSSASSSFSEEGAVGYSSDSETLDLEEAEGAVG-YQPEYSKFCR-MSYQDPSQLSCLPYLEHVGHNHTYNMAPSA
LDSADLPPPSTLKKGSKEKQA--------------------------DFLDKQMSRDEHRARAMKIPFTNDKIINLPVEE
FNELLSKYQLSEAQLSLIRDIRRRGKNKMAAQNCRKRKLDTILNLERDVEDLQRDKARLLREKQEIYRTVTD--------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------
>DOG_NFE2L1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------MLSLKKYLTEGLLQFTILLSLIGVRVDVDTYLTSQL
PPLR-----------EIILGPSSAYTQTQFHNLRNTLDGYGIHPKSIDLDNYFT-----ARRLLSQVRALDRFQVPTTEV
NAWLVHRDPEGSVSGS-QPSSGLTLESSSGLQDVTGPDNG------VRESETEQGFSEDLEDLGAVAPP-----------
-----------------VSGDLTKEDIDLIDILWRQDIDLGAGREIFDYSHRQKEQDVDKDL-----RDGAEQEDTWSGE
GAEALARN--LLVDGETGESFPAQFP-------------------------------ADISSITEAVPSESEPPGLQNNL
LSPLLTGTESPFDLEQQWQDLMSIMEMQAMEVN-TSTNEILYNAPPGDP----------LSTNYSLAP-NTPINQNVSLH
QASLGGCSQDF-SLFSPEAE---SLPVASGSTLLPLLPSNSTSLNSSFGSTNLAGLFFPPQLN-GTANDTAGPELPDPLG
GLLDEAMLDE----ISLMDLAIEEGFNPVQASQLEEEFDSDSGLSLDSSH-------SP---SSLSSSE-----------
--------ASSSFSEEGAVGYSSDSETLDLEEAEGAVG-YQPEYSKFCR-MSYQDPSQLSCLPYLEHVGHNHTYNMAPSA
LDSADLPPPSGLKKGSKEKQA--------------------------DFLDKQMSRDEHRARAMKIPFTNDKIINLPVEE
FNELLSKYQLSEAQLSLIRDIRRRGKNKMAAQNCRKRKLDTILNLERDVEDLQRDKARLLREKVEFLRSLRQMKQKVQSL
YQEVFGRLRDENGRPYSPSQYALQYAGDGSVLLIPRT-------------------------------------------
------------------------------------------------LAD-QQARRQERKPKDRRK-------------
-------------------
>HORSE_NFE2L1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------MLSLKKYLTEGLLQFTILLSLIGVRVDVDTYLTSQL
PPLR-----------EIILGPSSAYTQTQFHNLRNTLDGYGIHPKSIDLDNYFT-----ARRLLSQVRALDRFQVPTTEV
NAWLVHRDPEGSVSGS-QPSSSLILSVSSGHQDVTGSDNW------GRESKSVQRFMEDLEDFEAVAPP-----------
-----------------VSGDLSREDIDLIDILWRQDIDLGAGREIFDYSHRQKEQDVDKEL-----QDGAEQEDTWPGE
GAEALARN--LLVDGETGESFPAQVPGGEDQRALSLEECLRLLEATCPFGENAEF-PADISSITEAVPSESEPPGLQNNL
LSPLLTGTESPFDLEQQWQDLMSIMEMQAMEVN-TSTSEILYNAPPGDP----------LSTNYSLAP-NTPINQNVSLH
QASLGGCSQDF-SLFSPEVE---SLPVAGSSTLLPLAPSN-TSLSSTFESTNLLG-FFPPQLN-GTSPDTTDPELPDPVV
GVL?EAMLD?----ISLIDLASE?RLIP-AASQLEKKIDSYSCISWDSFI?PFLPE-QP?--RQLSSSSSSSSSSPLLSS
SS--ASSSASSSFSEEGAVGYSSDSETLDLEEAEGAVG-YQPEYSKFCR-MSYQDPSQLSCLPYLEHVGHNHTYNMAPSA
LDSADLPPPSTVKKGSKEKQA--------------------------DFLDKQMSRDEHRARAMKIPFTNDKIINLPVEE
FNELLSKYQLSEAQLSLIRDIRRRGKNKMAAQNCRKRKLDTILNLERDVEDLQRDKARLLQEKVEFLRSLRQMKQKVQSL
YQEVFGRLRDENGRPYSPSQYALQYAGDGSVLLIPRT-------------------------------------------
------------------------------------------------LAD-QQARRQERKPKDRRK-------------
-------------------
>PLATYPUS_NFE2L1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
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--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
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--------------------------------------------------------------------------------
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----GSCAQDC-ALFGGAAERESPPPGPGGAPLLPLTPGNATGLNSTFGATNLTGLFLPAPLN-GSANGTAGPELPDPLG
GLLDEAMLDE----ISLMDLVIEEGFNPVQASRLREELDSDSGLSLDSSHSPASSSGSPSSSASSSSSASSSSSSSSSSS
SSSSSSSSSSSSSSEEGAVGYSSDLETLDPEEAEGAVGGYQPEYSKLCR-MDSRDPAPLRYLPYLEHVDHNHTYNMVP--
-------------EPSKEKRA--------------------------DFLDKQMSRDEHRARAMKIPFTNDKIINLPVEE
FNELLSKYQLSDAQLGLIRDIRRRGKNKMAAQNCRKRKLDTILNLERDVEDLQRDKAQLLREKVEFLKSLRQMKQKVQSL
YQEVFGRLRDENGQPYSPSRYALQYASDGSVILIPRA-------------------------------------------
------------------------------------------------LAD-QQARRQDRKQKDRRK-------------
-------------------
>ZEBRAFINCH_NFE2L1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------PDPLG
GLLDEAMLDE----ISLMDLAIEEGFNPVQASQLEEEFDSDSGLSLDSGH-------SP---ASLSSSEASSSSSSSSS-
------SSSSSSFSEEGAVGYSSDSENVDLEEAEGAVG-YQPEYSKFCR-MSYQDPAQLHYLPYLEHVGHNHTYNMAPGA
LDPEEPKAPGAGKKSGKEKPS--------------------------ELLDKQLSRDEHRARAMKIPFTNDKIINLPVEE
FNELLSKYQLSEAQLSLIRDIRRRGKNKMAAQNCRKRMLDTILNLERDVEELQRDKSKLLREKVEFLKSIRQMKQKVQSL
YQEVFGRLRDEQGRPYSPSRYALQYGSDGSVLLIPRA-------------------------------------------
------------------------------------------------PAD-QERRREKKEEKEKQKLFRGSKQLLERFP
-------------------
>Human_NFE2L2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------MMDLELPPPGLPSQQDMDLIDILWRQDIDLGVSREVFDFSQRRK
EYELEKQKKLEK-ERQEQLQKEQEKAFFAQLQLDEETGEFLPIQPAQHIQSETSGS-ANYSQVAHIPKSD----------
--------------ALYFDDCMQLLAQTFPFVDDNEVSSATFQSLVPDIPGHIESPVFIATN-----QAQSPETSVAQVA
PVDLDGM-------------------------------------------------------------------------
-QQDIEQVWEELLSIPELQ-CLNIENDKLVETTMVPSPE-AKLTEVDN-----------YHFYSSIP----SMEKEVGNC
SPHFLNAFEDSFSSILSTEDPN---------QLTV--NSLNSDATVNTDFGDEFYSAFIAEPSISNS-MPSPATLSHSLS
ELLNGP--------IDVSDLSLCKAFNQNHPESTAEFNDSDSGISLNTSP------------SVASPEHSVESS-SYGDT
LL------------------GLSDSEVEELDSAPGSVKQNGPKT-PVHSSGDMVQPLSPSQGQSTHVHDA-QCENTPEKE
LPVSP-GHRKTPFTKDKHSSR----------------------------LEAHLTRDELRAKALHIPFPVEKIINLPVVD
FNEMMSKEQFNEAQLALIRDIRRRGKNKVAAQNCRKRKLENIVELEQDLDHLKDEKEKLLKEKGENDKSLHLLKKQLSTL
YLEVFSMLRDEDGKPYSPSEYSLQQTRDGNVFLVPKS-------------------------------------------
------------------------------------------------KKPDVKKN------------------------
-------------------
>Mouse_NFE2L2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------MMDLELPPPGLQSQQDMDLIDILWRQDIDLGVSREVFDFSQRQK
DYELEKQKKLEK-ERQEQLQKEQEKAFFAQFQLDEETGEFLPIQPAQHIQTDTSGS-ASYSQVAHIPKQD----------
--------------ALYFEDCMQLLAETFPFVDDH-------ESLALDIPSHAESSVFTAPH-----QAQSLNS-SLEAA
MTDLSSI-------------------------------------------------------------------------
-EQDMEQVWQELFSIPELQ-CLNTENKQLADTTAVPSPE-ATLTEMDSN----------YHFYSSIS----SLEKEVGNC
GPHFLHGFEDSFSSILSTDDAS---------QLT----SLDSNPTLNTDFGDEFYSAFIAEPSDGGS-MPSSAAISQSLS
ELLDGT--------IEGCDLSLCKAFNPKHAEGTMEFNDSDSGISLNTSP------------SRASPEHSVESS-IYGDP
PP------------------GFSDSEMEELDSAPGSVKQNGPKAQPAHSPGDTVQPLSPAQGHSAPMRES-QCENTTKKE
VPVSP-GHQKAPFTKDKHSSR----------------------------LEAHLTRDELRAKALHIPFPVEKIINLPVDD
FNEMMSKEQFNEAQLALIRDIRRRGKNKVAAQNCRKRKLENIVELEQDLGHLKDEREKLLREKGENDRNLHLLKRRLSTL
YLEVFSMLRDEDGKPYSPSEYSLQQTRDGNVFLVPKS-------------------------------------------
------------------------------------------------KKPDTKKN------------------------
-------------------
>Rat_NFE2L2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------MMDLELPPPGLQSQQDMDLIDILWRQDIDLGVSREVFDFSQRQK
DYELEKQKKLEK-ERQEQLQKEQEKAFFAQLQLDEETGEFLPIQPAQHIQTDTSGS-VSYSQVAHIPKQD----------
--------------ALYFEDCMQLLAETFPFVDDH-------ESLALDIPSHVESSVFTTPD-----QAQSLDS-SLETA
MTDLSSI-------------------------------------------------------------------------
-QQDMEQVWQELFSIPELQ-CLNTENKQQAETTTVPSPE-ATLTEMDSN----------YHFYSSIP----SLEKEVDSC
SPHFLHGFEDSFSSILSTDDAS---------QLN----SLDSNPTLNTDFGDEFYSAFLAEPSGGGS-MPSSAAISQSLS
ELLGGP--------IEGCDLSLCKAFNQKHTEGTVEFNDSDSGISLNTSP------------SRASPEHSVESS-IYGDP
PP------------------GFSDSEMEELDSAPGSVKQNGPKAQPTHSSGDTVQPLSPAQGHSAAVHES-QCENTTKKE
VPVSP-GHQKVPFTKDKHSSR----------------------------LEAHLTRDELRAKALHIPFPVEKIINLPVDD
FNEMMSKEQFNEAQLALIRDIRRRGKNKVAAQNCRKRKLENIVELEQDLGHLKDEREKLLREKGENDRNLHLLKRKLSTL
YLEVFSMLRDEDGKPYSPSEYSLQQTRDGNVFLVPKS-------------------------------------------
------------------------------------------------KKPDTKKN------------------------
-------------------
>Dog_NFE2L2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------MRSLLEKLG----KDMDLIDILWRQDIDLGVSREVFDFSQRRK
EHELEKQKKLEK-ERQEQLQKEQEKAFFAQLQLDEETGEFLPVQPAPHIPSETSAS-ANYSQVPHIPKPD----------
--------------ALYFDDCMQLLAETFPFVDDNEVSSAAFQSLVPDIPSQIENPVFIAPN-----QAQSPQTLAVQSV
IADLDNM-------------------------------------------------------------------------
-QQDIEQVWEELLSIPELQ-CLNIQNDKLVETSMVPSPE-TKMTEIDNN----------YHFYPSMP----SLEKEVGNC
SPPFLSAFEDSFSSILSTEDSS---------QLTV--NSLNSDATINTDFGDEFYSAFIAEPSSSNS-MPSSASFSQSLS
ELLNGP--------IDVSDLSLCKAFNQNHPEST-EFNDSDSGISLNTSP------------GMASPEHSVESS-VYGDT
AL------------------GFSDSEMEETDSAPGSVKQTGPKTQPGQSAGDPAQPPSPSPGPSAPAHDA-QCENTPKKE
SPVNP-GHRKAPFTKDKHSSR----------------------------LEAHLTRDELRAKALHIPFPVEKIINLPVDD
FNEMMSKEQFNEAQLALIRDIRRRGKNKVAAQNCRKRKLENIVELEQDLDHLKDEKEKLLKEKGENDKSLHLLKKQLSTL
YLEVFSMLRDEDGKPYSPSEYSLQQTRDGNVFLVPKS-------------------------------------------
------------------------------------------------KKPDIKKN------------------------
-------------------
>HORSE_NFE2L2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------MDLIDILWRQDIDLGVSREVFDFTQR-L
QHELEKQKTLERQERQEQLQKEQEKAFFAQLQLDEETGEFLPIQPAQHISSETSGS-ANFSQVSHIPKPD----------
--------------ALNFDDCMQLLAETFPFVDDNEVSPATFQSLVPDIPSNIESPDFIAPN-----QAQSPETLVLQPA
VADSDNM-------------------------------------------------------------------------
-QQDLEQVWEELLSIPELQ-CLNIQNDKLVETSTVPSSE-TKVTEIDNN----------YHFYSSIP----SLEKEVGNC
SPQLLNAFDDSFSSILSTEDTS---------QLTM--NSLNSEATINPDFGDGFYSAFV-EPSVSSS-MPSSATVSQSLS
ELLNGP--------IDVSDLSLCKAFNQNHPESTSEFNDSDSGISLRTSP------------SMASPEHSVESS-TYEDT
PL------------------GFSDSEMEETDSAPGSVKQNGPKTQPVQSSGDTVQPMSPSQGHSVPVHDA-QRENTPKKE
VPISP-GHRKTPLTKDKHSSR----------------------------LEVHLTRDELRAKALHIPFPVEKIINLPVED
FNEMMSKEQFNEAQLALIRDIRRRGKNKVAAQNCRKRKLENIVELEQDLDHLKDEKEKLLKEKGENDKSLHLLKKQLSTL
YLEVFSMLRDEDGRPYSPSEYSLQQTRDGSVFLVPKS-------------------------------------------
------------------------------------------------RKTDVKK-------------------------
-------------------
>Opossum_NFE2L2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------MNLIDILWRQDIDLGARREVFDFSQRRK
EHELEKQKKLEK-ERQEQLQKEQEKAFLAQLQLDEETGEFLPIQPAQHIEPSTS---ASYSQAADIPKAD----------
--------------ALFFDDCMQLLAETFPFVEDNEVSSATFQSLVPDHID--SNPVFITSS-----QAQLPESSVLQSI
VENN----------------------------------------------------------------------------
-MQDIEQVWEELLSIPELQ-CLNIENDKLAEATIVPSPE-AKPTEINDS----------YNFYTSLS----TMEKEVATC
NPDFLSAFEDSFGNILPTEDPN---------QLRM--NSLNSNATINTDFCEEFYSTFIAETNINNS-MPSPAHISQSLS
ELLNEP--------IDISDLSLCKAFNSNPPENPPECNDSDSGISLNTSS------------NMASPEHSVESS-LYGDT
PL------------------GFSDSEMEDVDSAPGSTQQSGARMQPVPFQEDMPYPVSPTQGPTVPAPDALQSVSTPKRE
SPTSP-GHQKVPFTKDKHSGR----------------------------LESHFTRDEMRAKALHIPFPVEKIINLPVDD
FNEMMSKEQFNEAQLALIRDIRRRGKNKVAAQNCRKRKLENIVELEQDLDHLKDEKEKLLRERGENDKSLHLLKKQLSTL
YLEVFSMLRDENGEPYSPSEYSLQQTRDGNVFLVPKS-------------------------------------------
------------------------------------------------KKPDIKRN------------------------
-------------------
>Platypus_NFE2L2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------MLRAHVRCQSRRECHRTGFPGCEVRPEPNAGYRRTDGS
WVAEAPLNQKPPPTPAFSSRGQVDHSPSFDFKHFPLPISYRPAQVEGFGRRKPLMRESRLWTETFDPSTTRSPVSINFRL
PFPLPTSTSHASREAQVRYPRAARAVGHPAVAVTVFERSQSAAPILERGRQLTSHGGGPGSGAGTPGQQERDRVASRSRG
TRREAGSSGHVSRRCPRCQRARVRRSLICLICLLRSGPGDLMSPGKQPARNPILVRGPKKESSMSQSSTCCPKEFGLWNF
SNRKLPTEPGGVYSQALASLAWCSWLPVFSAGAQRQKPGFDLHPSTFRLGAGLRGCSRSICYLYIGQEEAELEKIYLTLA
RQGEKSMTLDCTWLGSKVKNQEIHGLISEKVLFSAGVVRFTILSKLIGLDTDMNLIDILWRQDIDLGAGREVFDFCQRQK
EYELEKQKKLEK-ERQEQLQKEREQALLAQFQLDEETGEFLPIQPARPSQLEGGDGPAAFSQSPPTPKPD----------
--------------ALTFDDCMQLLTETFPFVDDNEVAPATLQSLSPPPAE--SSPVFVPPSP----TPAPAEAPVLEPA
ATDSAAM-------------------------------------------------------------------------
--QDIEQVWEELLSIPELQ-CLNIQNDKQAEAAPLPSPE-PKSGAADRP----------YGFYDVLSPLACTIEKEMSDS
SPAFLGAFEG---SALPTQDLS---------VSGA--CAQPPSPSLGPDFCEDFYTTFVVELEPGAEGAGAP---SRLLT
DLLNEP--------VDLADLALCKAFATPRPCGRPESNDADSGISLNTSP------------AAASPEPLADSV--DGDA
AP------------------GSSDSETDDVDSGP----PGGAKIRPHAG------------------AEGGRQADPPKKE
VLAGR-GPP--PGTRDRPAGR----------------------------LEAHFTRDEQRAKALQIPFPVEKIINLPVDD
FNEMMSKEQFSEAQLALIRDIRRRGKNKVAAQNCRKRKLENIVELEQDLDHLKDEKEKLLKEKGEHDLSLRLLKQQLSSL
YLEVFSMLRDQDGQPYSPADYSLQQTRDGHVFLVPKS-------------------------------------------
------------------------------------------------KKPVRAMQEQLEEKEKRV--------------
-------------------
>Zebrafinch_NFE2L2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------MNLIDILWRQDIDLGARREVFDSRQRQK
EYELEKQKKLEK-ERQEQLQKEQEEALLAQLELDEETGEFVPVQPAQCIQSENPEPPVAFSQTTEPSKQEAE--------
--------------ALSFDDCMQLLAEAFPFIDEHEASSAAFQSVAPAQVN--SNPPFVSSD-----QIQPPESPDLVQP
TDAEN---------------------------------------------------------------------------
-MQNIEQVWEELLSLPELQ-CLNIENDNLAEVSTVTSPE-PKPAEMHNS----------YSYCSSLP----MLKKD---C
SPDFLDGMEGTFSGILPPEDTS---------QLSV--NSLNDTSPSNSDFCEDFYSTFIDTKVNGD--AAATNTISQSLA
EILSEP--------IDLSDFALCKAFNGNRSGTRAEGTDSDSGISLNASS------------SVASPEHSVQSS-ACADK
TL------------------GCSDSDMEDTDSAPGSRLQNSAGVYSLHLQDQVLSSLGPS-----TQTPSLPRTATPKKE
PPPAP-GQPKAPFTKDKPPGR----------------------------LDAHLTRDEQRARALQIPFPVEKIINLPVAD
FSEMMSKEQFNEAQLTLIRDIRRRGKNKVAAQNCRKRKLENIVELEHDLSNLKDEKEKLLKEKGEHDRSLYQMKKQLTTL
YLEVFSMLRDEDGKPYSPSEYSLQQTRDGNVFLVPKS-------------------------------------------
------------------------------------------------RQSGTKL-------------------------
-------------------
>Chicken_NFE2L2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------MNLIDILWRQDIDLGARREVFDFSQRQK
EYELEKQKKLEK-ERQEQLQKEREKALLAQLVLDEETGEFVPAQPAQRVQSENAEPPISFSQSTDTSKPE-E--------
--------------ALSFDDCMQLLAEAFPFIDDNEASPAAFQSLVPDQID--SDPVFISAN-----QTQPPSSPGIVPL
TDAEN---------------------------------------------------------------------------
-MQNIEQVWEELLSLPELQ-CLNIENDNLAEVSTITSPE-TKPAEMHNS----------YDYYNSLP----IMRKDV-NC
GPDFLENIEGPFSSILQPDDSS---------QLNV--NSLNNSLTLSSDFCEDFYTNFICAKGDGD--TGTTNTISQSLA
DILSEP--------IDLSDFPLWRAFNDDHSGTVPECNDSDSGISLNANS------------SIASPEHSVESS-TCGDK
TF------------------GCSDSEMEDMDSSPGSVPQGNASVYSSRFPDQVLPSVEPG-----TQTPSLQRMNTPKKD
PPAGP-GHPKAPFTKDKPSGR----------------------------LEAHLTRDEQRAKALQIPFPVEKIINLPVDD
FNEMMSKEQFSEAQLALIRDIRRRGKNKVAAQNCRKRKLENIVELEQDLSHLKDEREKLLKEKGENDKSLRQMKKQLTTL
YIEVFSMLRDEDGKSYSPSEYSLQQTRDGNIFLVPKS-------------------------------------------
------------------------------------------------RKAETKL-------------------------
-------------------
>ANOLE_LIZARD_NFE2L2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------QDMNLIDILWRQDIDLGARREVFDFSQRKK
ASELEKQKKLER-ERQEQLQKEQEKAFLAQLQLDEETGEFVPIQPTQAIESGNTAISNNYSQNVHISKQDADN-------
------------LFSDVFDDCMQVLAETFLFVEDPKVSPVEFQQVAPSDIE--SNQVFVDPN-----HMQPLDSSVLQPA
ISEFAMTPG----------------------------------------------------------------------E
STQDMEQVWEELLSIPELQ-CLNIQNDNLAEVTPNTCTA-NTMSEAAID----------FTFYNPLP----PMENEVSTC
SPEFLKPLEASYSGILLPD------------------LSQNNTSSTSSDFCEDFYPDFIDVKANNSITSPPPNFVDQALT
GFLNEP--------IDLSDFAQCKAFNCDLAGNPQECTDSDSGISLNRSP------------STTSPAHSIDSSSICRDT
GF------------------GCSDTEIEEMDSAPGSVQQSNTQMPVFQF----LLPLSPPVEQRSPTAAS-PVKGEVKRE
LPANP-GHSEAPFMKDKSYSQ----------------------------DEAHLTRDELRAKALQIPFPVEKIINLPVDD
FNEMMSKEQFTEAQVTLIRDIRRRGKNKVAAQNCRKRKLENITELEYDLGYLKDEREKLLKEKAENDKSLHLLKKQLSTL
YLEVFGMLRDEDGKPYSVNEYSLQQTRDGGIFLVPKT-------------------------------------------
------------------------------------------------KKPGTK--------------------------
-------------------
>FROG_NFE2L2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------MMEIEMPLPLQSQQDMDLIDILWKQDIDLGVSREVFDYNQRQK
ENELEKQKKLEK-ERQEQLQKEREKALYAQLQLDEETGEFIPIQQAAPIETAAVTQELASSIEVKPSLVH----------
--------------DLSFDECLKILGETFQLGPANEESSLAYQTLEPSDPIE-TNQTFLQSE------PNPVPAGTLSSI
PAEGEIM-------------------------------------------------------------------------
--HEMNQAWEELLSIPELQ-CLNNEIENMVDLSMYTNQESITMTETPDT----------YSFLSPLS----TIEKP-HES
STVFSSDLVDTFTSSLP---------------------SVNTNTAFN---VESFCDDIFTLDPKVTNVVPLTDNSGQLLN
ELLNDN--------VDITDLSLCKAFNGN---NQPEFNDSDSGVSVNASP------------CATSPSQSMSGS-VYGEP
HH------------------SYSDSDMEDMDSTPETAQQKPPDNFTAAFTEDTYFTLSPFVSHDTDPFDI-EAHTPSAKE
IPASP-GYSKAPFAKDKYLSR----------------------------QEARFTRDEQRAKVLNIPFSVDKIVNLPVDN
FNELMSKYQFNEAQLALIRDIRRRGKNKVAAQNCRKRKMDNIVELETDLDKLKYEKEKLLAERGEYNNSLSQLKKKLGAL
YMEVFNKLQDENGQPYSPHEYSLQQTKEGNIFLVPKT-------------------------------------------
------------------------------------------------KKVSIKKE------------------------
-------------------
>FUGU_NFE2L2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------MTMEMDVMHSIQ-QDMNLIDILWKQDIDLGASREVFDYNHRQK
EHELQRQLEQQE-EKRLHLLREQEKALLAQLQLDEETGEYVP-RPVALPPLQSAVIPLEVSQVT--VSHSGD--------
--------------AMSFDECLQLLAETFP-VGETENSSVGLNTTEV-RPMLSPELAAVPS--------PTLSPDPLSA-
-SPSQAMC------------------------------------------------------------------------
--PELEEAWMELLSLPELQPCLNIKMEDAVETAAYPLPP---SPDAQNP---------NCQFYQTN--SAEVETNAINIC
PVEFLNTVEASVPSMVQSDHLT---------QAD--SPQFHTDFAAESFG-EMFYSNPVQKENTGQH--GLDGYNSDAMS
DMASQP-FTP----AGLYSLSPGDAFD--KHDLMAELPDSDSGISSHTSP------------NASSPG---KSV--YGDG
SF------------------HHSDSDMEEMDHNPGSAETDFSEMFSINFEPDDLQRTLSVSA-LERSEEQMEGKLEPHKM
DSVEECGQSGAPFTKDK-KRR----------------------------SDARLSRDEQRAKALKIPLSVSRIINLPVDD
FKELLSKHHLNDAQMALVQDIRRRGKNKVAAQNCRKRKMENIVGLEGELDSLKEEKERLLSEKVQKAAHLKEMKQQLNSL
YLEVFSKLRDEKGNSYSPSEYSLQQSTNGSIFLVPRV-------------------------------------------
------------------------------------------------KKTLAKSD------------------------
-------------------
>MEDAKA_NFE2L2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------FCLRLFFQDLDLIDILWKQDIDLGARREVFDYNHRQK
EHELQRQRQLEE-EKKLHLLREQEKALLAQLKLDEETGEYIP-HTKPILPPQQAVVSIEISQDANFTEETGD--------
--------------GMSFDECLQLLAETFP-VGETEVYKCMFAAQNPSVCMELPPVSVYPSGTMMPSEQPALSPAVLPNP
LTPPQRVT------------------------------------------------------------------------
--PDLEEAWMEILSLPELQ-CFKMQVDETMEATNFPIQT---SPQVQNPSYPNNQLFPNTPYYPMPS-ASDLKTKNLNVG
PGEFMNTCDGPVPSMAPSD-IS---------QINVEDPQVNPNFTPDSFCSSVFYPDTIVEESSSQH--GHEES--ENVS
EIPSKPSFTP----MDLYTLSPEDVFDR-SKRLPADFPDSDSGISTHSSP------------YSSSPS---KSA--YGGG
SY------------------NFSDSEMDDLDHNPGSAESDYSEMFSLNFQPEDLELAKPESE-QTGQCKQLDKKPKQHME
DPAEESGHSGTPFTKDKPKKR----------------------------SDVRLSRDEQRAKALKIPFTVSMIINLPVDD
FNEMMSKHELNEAQLALVRDIRRRGKNKVAAQNCRKRKMENIVGLEHELDLLKEEKERLLDEKSKNATNLKEMKRQLNSL
YLEVFGKLRDEKGNSYSPSEYSLQQSTDGSIFLVPRM-------------------------------------------
------------------------------------------------KKTYIKPH------------------------
-------------------
>STICKLEBACK_NFE2L2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------MIEMEVMHSGH-QDMELIDILWKQDIDLGARREVFDYNHRQK
EHELRRQRELEE-EKRQHLVREREKALLAQLQLDEETGEYIP-RPPAG-------APLEDTQNVNFPGETDD--------
--------------AMSFDECLQLLADTFP-VEETETASVCLDTAAVSAPMMSPEQPGLPP--------AALSTGPPLA-
-TPPERMS------------------------------------------------------------------------
--PDLEQAWMELLSLPELQQCLSMQMEDTLETTTYPLSN---SPEVQNP---------NYPFYPMN--ATDRLTNPLNVS
PAQFMNTFDGSLPSLVSPDSLH---------QVKENSPQLNAKFNAEIFC-DMFYPNDVLDESGG-----LEGNGSNAMP
DISNKPPFTP----VDLYSLSPDDAFDREKTNLTAERPDSDSGISSNTSP------------NASSPG---KSS--HGDE
SF------------------GFSDSDMEEMDDNPGSVESDYSDMFSLNFQPDHLHQAISLSARIGQPQQQQEKNPKEHKT
DPDEESGHNSSPFAKDKQKKR----------------------------SEKRLSRDEQRAKALKIPFTVDMIINLPVDD
FNEMMSKHQLNEAQLALVRDIRRRGKNKVAAQNCRKRKMENIVGLESNLDSLKEEKERLLGEKSQNATSLKEMKKQLNSL
YLEVFSTLRDEKGSSYSPSDYSLQQSTDGSVFLVPRV-------------------------------------------
------------------------------------------------KKTFLKSEDNLLSPL-----------------
-------------------
>TETRAODON_NFE2L2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------LLPVDFCASVIISEQDMNLIDILWKQDIDLGASREVFDYNHRQK
EHELQRQLELQE-EKRLHLLQEQEKALLAQLQLDEETGEYVP-RPAPVPALQSAIMPLEVSQDVGFPADSSD--------
--------------AMSFDECLQLLAETFP-VEETENTSVSLNASEV-APMASPELSVVPS--------TTQSPGSLSG-
-SSMPAMY------------------------------------------------------------------------
--PELEEAWMELLSLPELQPCLNIKMEDAVETTAYPLPN---SPAGQQP---------KGPFYPPN--CSKVETNNINVC
PAEFMNTVEGSVPRMVQSDHLN---------QAH--NPAFGADFAAKNFD-EMFYPNPILEESTGQR--GLDGSNSDAMS
DMASQP-FTP----ADLYSLSPGDALD--QHELMAELPDSDSGISSHTSP------------NASSPG---KSL--YGDG
SF------------------HHSDSDMDEMDQNPGSAETDFSEMFTINFQPDDLQPTPSESA-LQRSEQQMEGKLERHEM
DSVEECGPRCSPFTKDK-KRR----------------------------TDARLSRDEQRAKALKIPLSVSMIINLPVDD
FKELLSKHHLNDAQMALVQDIRRRGKNKVAAQNCRKRKMENIVGLEGELDSLKEEKERLLSEKVQRAAQLKQMKQQLSSL
YLEVFSKLRDDKGNSYSPSEYSLQQSTNGSIFLVPRV-------------------------------------------
------------------------------------------------KKTFAKSD------------------------
-------------------
>Human_NFE2L3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------MKLPKPWWAGGG-LLQLTILLSLVGLRVDLDLFLPPPA
AALW------------EELLPLCPTRPASASNPFSASEGWERTPLLPAK-----------GRLLHEVRALGVPFIPRTRV
DAWLVHSVATGNADGA------------HGLLGTAA--SSAVGDGG------QSASAGGGDPRAAHSSPLAAE-------
------------EEEE-KAAEPTAQVPDAGGCGSQENGMLREKSEAVDHSSQQEENEEGVSAQ---AKSRQQSKTEEHKM
ACASAREAE-----------------------------------------------------------KITEARNESHLH
WSDTSFSLEDLFQLLSS-QPEHSLEG-----ISVEDIPPFLSSVCESVN-----------SSAQN-INLSQAISHDVNLH
EAMLLYPNNTFRRDPSARSSQA--------QEPFLQLNP-HTNPEQATPAMSL----PPFDNQMRNLTS-------QDLL
YDLDSNIFDG----INLMSLATG--FSPLEVSQLFEEP--DSGLSLNSSY------------NSTSLTN---SYRIYDG-
-----------------TVGYNSDLQSLCHD--LGAVGGCYPEPHKHCH-MDHRTIAGFHVSLECQQVFHDHTYHLQSGA
SEPTSES--FAWSEKSQKTS------------------------GCLDNPDRNLSRDEQRAKALHIPFSVDEIVRMPVDS
FNSMLSRYYLTDLQVSLIRDIRRRGKNKVAAQNCRKRKLDIILNLEDDICNLQAKKEALKNEQTQCSKAIDIMRQKLHGL
HQDVFNRLRDDQGRPVNPSQYALQYSHDGTVLIVPKE-------------------------------------------
------------------------------------------------LISSGHKKEAPKGKRERRN-------------
-------------------
>Mouse_NFE2L3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------MKLPKPWWAGGG-LLQLTILLSLVGLRVDLDLFLPPPA
AALW------------EELLPLCPTRPASASNPFSASEGWERTPLLPAK-----------GRLLHEVRALGVPFIPRTRV
DAWLVHSVATGNADGA------------HGLLGTAA--SSAVGDGG------QSASAGGGDPRAAHSSPLAAE-------
------------EEEE-KAAEPTAQVPDAGGCGSQENGMLREKSEAVDHSSQQEENEEGVSAQ---AKSRQQSKTEEHKM
ACASAREAE-----------------------------------------------------------KITEARNESHLH
WSDTSFSLEDLFQLLSS-QPEHSLEG-----ISVEDIPPFLSSVCESVN-----------SSAQN-INLSQAISHDVNLH
EAMLLYPNNTFRRDPSARSSQA--------QEPFLQLNP-HTNPEQATPAMSL----PPFDNQMRNLTS-------QDLL
YDLDSNIFDG----INLMSLATG--FSPLEVSQLFEEP--DSGLSLNSSY------------NSTSLTN---SYRIYDG-
-----------------TVGYNSDLQSLCHD--LGAVGGCYPEPHKHCH-MDHRTIAGFHVSLECQQVFHDHTYHLQSGA
SEPTSES--FAWSEKSQKTS------------------------GCLDNPDRNLSRDEQRAKALHIPFSVDEIVRMPVDS
FNSMLSRYYLTDLQVSLIRDIRRRGKNKVAAQNCRKRKLDIILNLEDDICNLQAKKEALKNEQTQCSKAIDIMRQKLHGL
HQDVFNRLRDDQGRPVNPSQYALQYSHDGTVLIVPKE-------------------------------------------
------------------------------------------------LISSGHKKEAPKGKRERRN-------------
-------------------
>Rat_NFE2L3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------MRAGFNCGALPGNGAGPESWELQVSSLPIWVPGSSRHCVGSRGSAFV
PGWGEAATAPCTPWSFVFPAGATRAAVGPGRVDTGISGAPWEMKLPKPWWASGG-LLHLRLLLSLVGLRVDLDLCLLPPV
AALW------------EELLPFFPTRPASASNPFSASEGWGRTPLLPAK-----------GRLLHEVRALGVPFIPRTLV
DAWLVHSVATGDADGT------------HGLLGTAA--SSAVGDGG------QSASAGGGDPGEAHSSPLAAE-------
------------EEEEEKAAEPTAQVPDAGGRGSQETEVLSEKSEAVDHSSQQKENEEGVSAQ---ATSRQQRKREENKM
TGASAWEAE-----------------------------------------------------------KIVEARNESHLH
WSDTSFSLEDLFQLLSS-QPEHSLEG-----ISVEDIPPFLSSVCESVN-----------PSVHN-INLNQAISHDVNLH
EAMLLCSNTSIR-DPSARPSQA--------QEPFLQLNS-PTSPQQAIPAMSL----PLANNQMRNLTS-------QDLL
YDLDSNIFDG----LNLMSLATG--FSPLEVSQLFEEP--DSGVSLNSSY------------NSTSLTN---SNCTFDG-
-----------------TN--------------LGAVGGCYPEPRKHCH-VDHRTISGFHGALECHQVFHDHTYHLQSGV
PEATSET--FTWTGKSQKIS------------------------GCLDDPDRNLSRDEERAKAMHIPFSVDEIVHMPVDS
FNSMLSRYYLTDSQVSLIRDIRRRGKNKVAAQNCRKRKLDIILNLEDDICNLQAKKEALKSEQTQWNKAINTMRQKLYDL
YHNVLNRLRDDQGRPVNPSHYALQYSHDGTILIVPKE-------------------------------------------
------------------------------------------------LVSSGHKKEVPKVKRERN--------------
-------------------
>Cow_NFE2L3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------MKYLKPWWSDGGSLFHLTILLSLAELRLDLDLDLDLDL
YLLFPPRT----LLGDELLLRNGQTSHISALSPFPASGGWGRAELLHPKCWERDPAAPPEGRLLREVRALGVPFIPSIRV
DAWLVHSVATGDADGA------------HALLGAAA-ASSAGGVGAGVEGVSQAAPGGGGGPRAVQSSPLAAG-------
------------EEEEKAPAERTAQVSDADGHASEENEVLRG----VSHSPQHEENEQRSSTQ--KEKSLQQKNEDENKV
ADKPAWEAE-----------------------------------------------------------KTTESRSERYQN
GTDAFFSLEDLFQLLSS-QPENLLEG-----VSLGDIAPLPRSINDGMN-----------SPTHYNVNFSEAVSHDVSLH
EAMLRCSDNTFRRDPVARTSQP--------QEQILQLSS-ITNTEQTLPGTNLTGFLPFVDNQMRNLS--------QDHL
YDLDINILDE----TNLMSLATG--FDPMEVSWLLEEPGYDSGLSLDSSN------------NSTSVIKSNSSHSICEG-
-----------------ATGSSSD---LSHHDLEGAVGGYCPEPSKLCY-MNDKSDSHFHGDLVFQHVSHNHTYHLEPSA
LESTSES--FSMPGKSQKIS------------------------RYLNDTDRNLSRDEQRAKALHIPFSVDEIIRMPVDS
FNSMLSRHYLTDLQVSLIRDIRRRGKNKVAAQNCRKRKLDVILNLEDDVCSLQAKKETLKREQSQCHKAINIMKQKLHHL
YCDVFSRLRDDQGRPVSPNQYALQCTHDGSVVIVPKE-------------------------------------------
------------------------------------------------LIIPGQKKENQKGKRKNERKN-----------
-------------------
>Dog_NFE2L3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------MLVSCHMSFYIGLTHNI
AALS-----------KKERIRDAERSATYALSPFAASAGWGRADQLHPKGREPE----PEGRLLREVRALGVPFIPRTRV
DAWLVHSVAAADADGA------------HGLLGATASAASAGGVGAGVEDSSQAAPGDGD-PRAAASSPVAAG-------
------------EEE-RAPAGPTAQVLDAGGRANQGSEVLREKHEAVDHSSQNEENEQRVSSA--QERS--QKNE-ESKI
ANNPDWEAE-----------------------------------------------------------KPTESSNERALN
GTDTAFSLEDLFQMFSS-QPENSLEG-----ISLEDT--FPGNINDGVN-----------SSIHHNVNFSQAISQDVNLH
EAMLLCPDNTFRREPVARTSQ----------EPFLHLNSQNTNSEQNLPGTNLTGFFPLVGNQMRNLTS-------QDLL
YDLDLNIFDE----INLMSLATG--FDPMEVAQLFEEPDSDSGLSLNSSH------------NSTSVTKSNSSHSVCEG-
-----------------ATGSSSDLESLSHHDLEGAVGGYYAEPSKLCH-MDHRSNSGFHGDLTFQHVFHNHTYHLQPSA
LESTSTS--LSRHGKSQKSR------------------------RYLNDTDRNLSRDERRAKALHIPFSVDEIVRMPVDS
FNNNLSRHYLTDLQVSLIRDIRRRGKNKVAAQNCRKRKLDIILNLEDDVCNLQAKREILKRERARYNKAINTMKQKLHEL
YHDIFSRLRDDEGRPVNPNQYVLQCSQDGSVLIVPKE-------------------------------------------
------------------------------------------------LVTSGHKKENHKGKRK----------------
-------------------
>Horse_NFE2L3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------MTAPNVEAQIHT
YSLE-----------NPGAVAPNKEQHLWALELDLFVHPVPPSSVPTAS----------EGQLLREVRALGVPFIPRTRV
DAWLVHRVAAGDADGA------------HGLLGAAA-ASSAGGVGAGVDGGSQAAPGGGGDPRASPSSPLAAR-------
------------QEE-KAPAEQTARVPDADGRASEENEVLRERHEAVDHSSQHEENEQRVSAQ--EEKSLQQKNEDENKT
ADKPDWEAE-----------------------------------------------------------KTTESRNERHLN
GTDTSFSMEDLFQLLSSSQPENSVEG-----ISLGDIPALPGSSNDGMN-----------SSAHYNVNFSQAISHDVNLH
EAMLLCPDNTFRRDPVVRTSQP--------QEPFLQLNSHTTNAEQSLPVANLTAFLPFVDNQMRNLTS-------EDFL
HDLNINIFDE----INLMSLATGD-LDAMEVSQLFQEPDSDSGLSLNSSH------------NSTSITKSNTSHSICEEG
-----------------ATGYSSDPESLPHHNLEGAVGGNYPAP------MGHRSDSGFCGDLAFQHVFHNHTYHLEPRA
LESNSES--FSWPEKPEKMS------------------------RYLSDTERNLSRDERRAKALRIPFSVDEIVRMPVDS
FNSMLSRHYLTDLQVSLIRDIRRRGKNKVAAQNCRRRKMDIILNLEEDVCNLQAKKETLKRERAQCNKAINIMKQKLHHL
YHDVFSRLRDDEGRPVNPNQYALQYSHDGSVLIVPKE-------------------------------------------
------------------------------------------------LVTSGHKKENRKRKREGIEDGFH---------
-------------------
>Opossum_NFE2L3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------MLSLKKYLTEGLLQFTILLSLIGVRVDVDTYLNSQL
PPLR-----------EIILGPSSAYTQTQFHNLRNTLDGYGIHPKSVDLDYYFT-----ARRLLNQVRALDRFQVPTTEV
NAWLVHRDPEGSVSGS-QPSSALALESASGLQDVTGSESG------VRESEAEQGFGEELEDLGAVAPP-----------
-----------------VSGELTKEDIDLIDILWRQDIDLGAGREIFDYSHRQKESEVDKEL-----RDGGECGDSWPNE
GTEALAGN--LLVDGETGESFPAQFP------------------------------TADVSSITEAVPSESESSAIQNNL
LSPLLTETESPFDLEQQWQDLMSIMEMQAMEVN-TATNEILYSATTGDA----------LSTNYSLAP-NTPINQNVSLH
QASLGSCAQDF-SLFSPEIE---SLPVANGSTLLQLAPNNSTSLNSTFGSTNLTGIFFPPQLN-STANETANPELPDPLG
GLLDEAMLDE----ISLMDLAIEEGFNPVQASQLEEEFDSDSGLSLDSSH-------SP---ASLSSSEGSSSASSS---
----ASSSASSSFSEEGAVGYSSDSENLDLEEPEGAVG-YQPEYTKFCR-MSYQDPSQLSYLPFLEHVGHNHTYNMAPGA
LDTSEPQLNGVLKKGSREKQA--------------------------DFLDKQMSRDEHRARAMKIPFTNDKIINLPVEE
FNELLSKYQLSEAQLSLIRDIRRRGKNKMAAQNCRKRKLDTILNLERDVEDLQRDKSKLLREKVEFLKSLRQMKQKVQSL
YQEVFGRLRDENGQPYSPTQYALQYAGDGSVILIPRT-------------------------------------------
------------------------------------------------MAD-QQARRQEKKQKDRRK-------------
-------------------
>Platypus_NFE2L3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------MRPPK
YNIR--------------------KAQRASSGRMETSG--PPPPVFPRR-----------SSTGLQVRVSAVPLSGLEGC
GLALLRGRVAEDDD--------------LPILVASS-------------------------PCPDQRS--TED-------
------------KKRWVWSARPLADVAVAN---------------TVCHS------------------------------
-VVPVAVAS-----------------------------------------------------------ALSTSRNE----
-ADGTLSLEDMFQLFSS-QTENAPKG-----ISLGDVQPATSESRGGSS-----------SSRHS-VNFTQAISHDVSLH
EATLLSSD-ASRRNSGSENCRS--------QETFLPFNSSSTNSSQSPSASNLTALFPFVDTSVGNATS-------QDLL
PGLDDNIFDE----INLMSLALEEGFNPLAVSRLFEEPDSDSGLSLNSSR------------SSASASNSDSSALACNGE
G----------------AVGYGSDVGSPRHDGLEGAVGSDWPESGRLRRPGDYLGDPETPGKPTFRHVLHNHTYHLLPDP
ALSTPESP-DSWPGTSPQVRD-----------------------RDLRDLER