>Homo_sapiens_UNC5A
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------MAVRPGLWPALLGIVLAAWLR-GSGAQQSATVAN----PVPGAN------PDLLPHFLVEPEDVYIVKNKPV
LLVCKAVPATQIFFKCNGEWVRQVDHVIERSTDGSSGLP-----------------------------------------
---------------------------TMEVRINVSRQQVEKVFG--LEEYWCQCVAWSS--SGTTKSQK----------
--------------------------------------------------------------------------------
------------------------------------------------------AYIRIAYLRKN---------------
---FEQEPLAKEVSLEQGIVLPCRPPEGIPPAEVEWLRNEDLVDPSLDPNVYITREH-----------------------
------------------------------------------------------------------SLVVRQARLADTAN
YTCVAKNIVARRRSASA------------------AVIVY--------------------------------------V-
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------DGSWSPWSKWSACGLDCTH------------------------------
--------------------------------------------------------------------------------
----------WRSRECSDPAPRNGGE---ECQGTDLDTRNCTSDLCVHTA----------------------------SG
PEDVALYVG----LIAVAVCLVLLLLVLILVYCRKKEGL-----------------------------------------
----------DSDVADSS----ILTSG-FQPVSIKPSKADNP-------------------------------HLLTIQP
DLSTTTTTYQGSLCPRQ-----DGPSPKFQLTNGHLLS------------------------------------------
--------------------------------------------------------------------------------
-PLGGGRHTLHHSSPTS-----------EAEEFVSR--------------------------------------------
--LSTQN-------YFRSLPRGTSNMTYGTFN-----FLG-----------------GRLMIPNT---------------
---------------------------------------------------------------------------GISLL
IPPDAIPRGKIYEIYLTLHKPEDV--------------------------------------------------------
---------------------------------------RLPLAGCQTLLSPIVSCGPPGVLLTRPVILAMDHCGEPSPD
--SWSLRLKKQS------------------CEGSWE--------------------------------------------
-------------------------------DVLHLGEEA------------PSHLYYCQLEASACYVFTEQLGR-FALV
GEA---LSVA-AAKRLKLLLFAP-VACTSLEYNIRVY---------------CLHDTHDALKE-VVQLEKQLG-------
------------------------------------------------------------------------------GQ
LIQEPR---VLHFKDSYHNLRLSIHDVPSSLWKSKLLVSY-QEIPFYHIWNG-TQRYLHCTFTLERVSPSTSDLA-----
--------------------------------------------------------------------------------
---------------------------------------------------------CKLWVWQVEGDGQSFSINFNITK
--------------------------------DTRFAELLALESEAGVPALVGPSAFKIPFLIRQKIISSLDPPCRRG--
-ADWRTLAQKLHLD----SHLSFFASKPS----PTAMILNLWEARHFPN---------GNLSQLAAAVAGLGQPDAGLFT
-----------VSEAEC---------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------
>Macaca_mulatta_UNC5A
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------TGAQQSATVAN----PVPGAN------PDLLPHFLVEPEDVYIVKNKPV
LLVCKAVPATQIFFKCNGEWVRQVDHVIERSTDGSSGLP-----------------------------------------
---------------------------TMEVRINVSRQQVEKVFG--LEEYWCQCVAWSS--SGTTKSQK----------
--------------------------------------------------------------------------------
------------------------------------------------------AYIRIAYLRKN---------------
---FEQEPLAKEVSLEQGIVLPCRPPEGIPPAEVEWLRNEDLVDPSLDPNVYITREH-----------------------
------------------------------------------------------------------SLVVRQARLADTAN
YTCVAKNIVARRRSASA------------------AVIVY--------------------------------------V-
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------DGSWSPWSKWSACGLDCTH------------------------------
--------------------------------------------------------------------------------
----------WRSRECSDPAPRNGGE---ECQGADLDTRNCTTDLCVHTA----------------------------SG
PEDVALYVG----LIAVAVCLVLLLLVLILVYCRKKEGL-----------------------------------------
----------DSDVADSS----ILTSG-FQPVSIKPSKADNP-------------------------------HLLTIQP
DLSTTTTTYQGSLCPRQ-----DGPSPKFQLTNGHLLS------------------------------------------
--------------------------------------------------------------------------------
-PLGGGRHTLHHSSPTS-----------EAEEFVSR--------------------------------------------
--LSTQN-------YFRSLPRGTSNMTYGTFN-----FLG-----------------GRLMIPNT---------------
---------------------------------------------------------------------------GISLL
IPPDAIPRGKIYEIYLTLHKPEDV--------------------------------------------------------
---------------------------------------RLPLAGCQTLLSPIVSCGPPGVLLTRPVILAMDHCGEPSPD
--SWSLRLKKQS------------------CEGSWE--------------------------------------------
-------------------------------DVLHLGEEA------------PSHLYYCQLEASACYVFTEQLGR-FALV
GEA---LSVA-AAKRLKLLLFAP-VACTSLEYNIRVY---------------CLHDTHDALKE-VVQLEKQLG-------
------------------------------------------------------------------------------GQ
LIQEPR---VLHFKDSYHNLRLSIHDVPSSLWQSKLLVSY-QEIPFYHIWNG-TQQYLHCTFTLERVSPSTSDLA-----
--------------------------------------------------------------------------------
---------------------------------------------------------CKLWVWQVEGDGQSFNINFNITK
--------------------------------DTRFAELLALESEGGVPALVGPSAFKIPFLIRQKIISSLDPPCNRG--
-ADWRTLAQKLHLD----SHLSFFASKPS----PTAMILNLWEARHFPN---------GNLSQLAAAVAGLGQPDAGLFT
-----------VSEAEC---------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------
>Mus_musculus_UNC5A
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------MAVRPGLWPALLGIVLTAWLR-GSGAQQSATVAN----PVPGAN------PDLLPHFLVEPEDVYIVKNKPV
LLVCKAVPATQIFFKCNGEWVRQVDHVIERSTDGSSGLP-----------------------------------------
---------------------------TMEVRINVSRQQVEKVFG--LEEYWCQCVAWSS--SGTTKSQK----------
--------------------------------------------------------------------------------
------------------------------------------------------AYIRIAYLRKN---------------
---FEQEPLAKEVSLEQGIVLPCRPPEGIPPAEVEWLRNEDLVDPSLDPNVYITREH-----------------------
------------------------------------------------------------------SLVVRQARLADTAN
YTCVAKNIVARRRSASA------------------AVIVY--------------------------------------VN
GGWST-WTEWSVCSAS---------------CGRGWQKRSRSCTNPAPLNGGAFCEGQNVQKTACATLCP----------
--------------------------------------------------------------------------------
------------------------------VDGSWSPWSKWSACGLDCTH------------------------------
--------------------------------------------------------------------------------
----------WRSRECSDPAPRNGGE---ECRGADLDTRNCTSDLCLHTS----------------------------SG
PEDVALYIG----LVAVAVCLILLLLVLVLIYCRKKEGL-----------------------------------------
----------DSDVADSS----ILTSG-FQPVSIKPSKADNP-------------------------------HLLTIQP
DLSTTTTTYQGSLCPRQ-----DGPSPKFQLSNGHLLS------------------------------------------
--------------------------------------------------------------------------------
-PLGSGRHTLHHSSPTS-----------EAEDFVSR--------------------------------------------
--LSTQN-------YFRSLPRGTSNMAYGTFN-----FLG-----------------GRLMIPNT---------------
---------------------------------------------------------------------------GISLL
IPPDAIPRGKIYEIYLTLHKPEDV--------------------------------------------------------
---------------------------------------RLPLAGCQTLLSPIVSCGPPGVLLTRPVILAMDHCGEPSPD
--SWSLRLKKQS------------------CEGSWE--------------------------------------------
-------------------------------DVLHLGEES------------PSHLYYCQLEAGACYVFTEQLGR-FALV
GEA---LSVA-ATKRLRLLLFAP-VACTSLEYNIRVY---------------CLHDTHDALKE-VVQLEKQLG-------
------------------------------------------------------------------------------GQ
LIQEPR---VLHFKDSYHNLRLSIHDVPSSLWKSKLLVSY-QEIPFYHIWNG-TQQYLHCTFTLERVNASTSDLA-----
--------------------------------------------------------------------------------
---------------------------------------------------------CKVWVWQVEGDGQSFNINFNITK
--------------------------------DTRFAEMLALESEGGVPALVGPSAFKIPFLIRQKIITSLDPPCSRG--
-ADWRTLAQKLHLD----SHLSFFASKPS----PTAMILNLWEARHFPN---------GNLGQLAAAVAGLGQPDAGLFT
-----------VSEAEC---------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------
>Gallus_gallus_UNC5A
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------GGDSCRTWSRWCPWRWLSSHVPTGAQQSVTVAS----PASGAS------PDLLPHFLLEPDDVYIVKNKAV
SLACRATPATQIYFKCNGEWVHQGDHITQRSTDRGTGLP-----------------------------------------
---------------------------VMEVRIEITRQQVEKLFG--LEEYWCQCVAWSS--SGTTKSQK----------
--------------------------------------------------------------------------------
------------------------------------------------------AFVRIAYLRKN---------------
---FEQEPTAREVSIEQGVVLPCRPPEGIPPAEVEWLRNEELVDPALDANVLVTPEH-----------------------
------------------------------------------------------------------SLVLRQARLADTAN
YTCVAKNIVARRRSASA------------------AITVY--------------------------------------VN
GGWST-WTQWSGCSTS---------------CGRGWQKRSRTCTNPTPLNGGAFCEGQNVQKSACTTLCP----------
--------------------------------------------------------------------------------
------------------------------VDGDWSEWSKWSVCGAECTH------------------------------
--------------------------------------------------------------------------------
----------WRSRECSEPAPRNGGQ---ECHGPELETHNCTSELCSPMCPRG----AD------------NLPHAATPG
AEDLALYVG----LIAVAVCLVLLLLVGVLVYCRKKGGL-----------------------------------------
----------DADVADSS----ILTTG-FQPVSIKPSKADN---------------------------------LLTIQP
DLSTATMTYQGSLCPRQ-----DG-PAKLQLPNGHLLS------------------------------------------
--------------------------------------------------------------------------------
-PLGAGRHTLHHSSPAA-----------EGADFVAR--------------------------------------------
--LSTQS-------YFRSLPRGTANMAYGTFN-----FLG-----------------GRLMIPNT---------------
---------------------------------------------------------------------------GVSLL
IPPDAIPRGKIYEVYLTLHKHEEV--------------------------------------------------------
---------------------------------------RLPLAGCQTLLSPIVSCGPPGVLLTRPAILAMGHCVEAGAE
--HWSLRLKKQS------------------CEGTWE--------------------------------------------
-------------------------------DVLQLGAEP------------RTELYYCQLEAQACYIFTEQLGR-FALV
GES---LSMA-ASKRLKLVLFAP-TACPSLEYNIRVY---------------CLSDTQDALKE-VMQLEKQMG-------
------------------------------------------------------------------------------GQ
LIGAPR---VLHFKDSYHNLRLSIHDMPSSLWKSKLLASY-QEIPFYHIWSG-LQPYLHCTFTLERLSPSTCELA-----
--------------------------------------------------------------------------------
---------------------------------------------------------CKIWIWQVEGDGQSFTINCNIAK
--------------------------------DTRFSDWLVPDSEVGSPALVGPSAFKIPFLIRQKIISSLDTPCARG--
-ADWRTLAQKLNLD----SHVSFYASKPS----PTAMILNLWEARHFPN---------GNLSQLAAAVAEVGKQDSALFA
-----------VSEAEC---------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------
>Taeniopygia_guttata_UNC5A
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------TGAQQSATVAN----PASGAS------SDLLPHFQLEPEDVYIVKNKAV
SLACRATPATQIYFKCNGEWVHQGDHVTQHSTDRGTGLP-----------------------------------------
---------------------------VMEVRIEVTRQQVEKIFG--LEEYWCQCVAWSS--SGTTKSQK----------
--------------------------------------------------------------------------------
------------------------------------------------------AFVRIAYLRKN---------------
---FEQEPTAREVSIEQGIVLPCRPPEGIPPAEVEWLRNEELVDPELDANVYVTPEH-----------------------
------------------------------------------------------------------SLVLRQARLADTAN
YTCVAKNIVARRRSASA------------------AIIVY--------------------------------------VN
GGWST-WTQWSGCSTS---------------CGRGWQKRSRTCTNPTPLNGGAFCEGQNVQKTACTTLCP----------
--------------------------------------------------------------------------------
------------------------------VDGAWSEWSKWSECGAECTH------------------------------
--------------------------------------------------------------------------------
----------WRSRECSEPAPRNGGR---DCHGPELDTRNCTSELCT----------------------------HAAPG
AEDVALYVG----LVAVAVCLVLLLLVGVLVYCRKKGGL-----------------------------------------
----------DADVADSS----ILTAG-FQPVSIKPSKADNP-------------------------------SLLTIQP
DLSTTTMTYQGSLCPRQ-----DG-PAKLQLPNGHLLS------------------------------------------
--------------------------------------------------------------------------------
-PLGAGRHTLHHSSPAA-----------EGADFVAR--------------------------------------------
--LSTQS-------YFRSLPRGTNNMAYGTFN-----FLG-----------------GRLMIPNT---------------
---------------------------------------------------------------------------GISLL
IPPDAIPRGKIYEVYLTLHKQEEV--------------------------------------------------------
---------------------------------------RLPLAGCQTLLSPIVSCGPPGVLLTRPAILAMGHCVEASAE
--NWSIRLKKQS------------------CEGTWE--------------------------------------------
-------------------------------DVLQLGAEP------------CTELYYCQLEAQACYVFTEQLGR-FALV
GES---LSMA-ASKRLKLVLFAP-AACPSLEYNIRVY---------------CLRDPQDVLKE-VIQLEKQLG-------
------------------------------------------------------------------------------GQ
LIGAPR---VLHFKDSYHNLRLSIHDMPSSLWKSKLLASY-QEIPFYHIWSG-LQPFLHCTFTLERLSTSTCELA-----
--------------------------------------------------------------------------------
---------------------------------------------------------CKIWVWQVEGDGQSFTVNFNIAK
--------------------------------DTRFSDWLVPD-EVGTPALVGP-AFKIPFLIRQKIISSLDPPGTRG--
-ADWRTLAQKLNLD----SHLSIFASKPS----HTAMILNLWEARHFPN---------GNLSQLAAAVAEVGKQDGALF-
------------SEAEC---------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------
>Danio_rerio_UNC5A_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------SGLP-----------------------------------------
---------------------------VMQVKIDISRQQVEKIFG--LEDYWCQCVAWST--TGTQKSQK----------
--------------------------------------------------------------------------------
------------------------------------------------------AFVRIAYLRKN---------------
---FEEEPLGKEVALDQELLLRCHPPEGVPPAEVEWQRNEELIDPKTDPNFFITTDH-----------------------
------------------------------------------------------------------NLIIKQTRLADTGN
YTCVAKNIVARRKSSSA------------------TVIVY--------------------------------------VN
GGWST-WATWSSCSAV---------------CGRGWQKRSRSCTNPTPLNGGTSCEGQSLQKSACTATCP----------
--------------------------------------------------------------------------------
------------------------------VDGGWSEWSKWSPCGADCSM------------------------------
--------------------------------------------------------------------------------
----------WRSRECTQPTPGTGGK---DCQGLDLQSLNCTSEQCPQTAS----------------------------G
AEDVALYVG----MVTVALCLALLLVVLVLVYRRKKEGL-----------------------------------------
----------DADVADSS----ILTTG-FQPMGIKPSKPENS-------------------------------HLLTIQP
DLTTSTSSYQGSLRSRH-----EV-SSKFSMSNGPLLD------------------------------------------
--------------------------------------------------------------------------------
-PLPNGSHTLHNGKLSS-----------DADDFMSR--------------------------------------------
--LSSQT-------YLKTLPRENGNTSYGTFNFLG----------------------GRLTLPNT---------------
---------------------------------------------------------------------------GISLL
IPPEAIPRGKIYEIYLTIQKKEDMS-------------------------------------------------------
---------------------------------------RLPLAGCQTLLSPVVSCGPPGVMLTRPVILCMDHCSDACLE
--NWAIRLKKQS------------------YEGTWE--------------------------------------------
-------------------------------DVLLLGEDL------------LSEPYYCQLEAETCRVFTEQLGR-FALV
GES---LSMA-AAKRLKLLLFAP-AYCSTLEYNIRVY---------------CTDDTQDLLKE-VMQMERQLG-------
------------------------------------------------------------------------------GR
LIDEPH---VLLFKDSYHNLRLSIHDMPHTHWRSKLLAGY-QEIPFYHIWSG-SQRTLHCSFTLERQSLSTSDLS-----
--------------------------------------------------------------------------------
---------------------------------------------------------CTLCVWQVEGEGQSFSLDFNIAK
--------------------------------DIRPLDSDFLLLENCSPALAGPSAFQIPYLIRQKICSSLDAPCPNG--
-ADWRLLAQRLKLD----RY------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------
>Takifugu_rubripes_UNC5A_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------GAEHAATATLPAAF------SDLLPHFQVEPEDEYIVKNKPV
TLTCRSTPATQIYFKCNGEWVHQDDHLIERTVDPATALP-----------------------------------------
---------------------------IMQVTIDITRQQVEKIFG--LDQYWCQCVAWST--TGTQKSQK----------
--------------------------------------------------------------------------------
------------------------------------------------------AYIRIAYLRKN---------------
---FEEEPQGKEVALDQEVLLRCHPPEGVPQPEVEWQRNEDILNPESDPNFFVTADH-----------------------
------------------------------------------------------------------NLIIRKARMADTGN
YTCVAKNIVARRKSTSA------------------AVLVYGGAFALLIFFHVVSCQQVRIWHLRAFKPSPPAPALT--VN
GGWST-WTTWSSCSAV---------------CGRGWQKRSRSCTNPTPLNGGSSCEGQNIQKSVCVATCP----------
--------------------------------------------------------------------------------
------------------------------VDGGWSEWSKWSACGADCSM------------------------------
--------------------------------------------------------------------------------
----------WRTRECTQPSPGTGGK---DCQGLDLQSLNCTSEQCPQSYG----------SRLTL-----LLSVAAVSG
AEDVALYVG----VVAVALCLTLLLIVVVLVYRRKKEGL-----------------------------------------
----------DADVADSS----ILTTG-FQPMGIKPSKPENS-------------------------------HLLTIQP
DLTTTTTSYQGTLRSRH-----DT-TGKFSMTNGTLLD------------------------------------------
--------------------------------------------------------------------------------
-PLPNGSHTLHNGKLNP-----------DPPEFVSR--------------------------------------------
--LSTQS-------YFKTLPRDVANASYGTFNFLG----------------------GRLTIPNT---------------
---------------------------------------------------------------------------GISLL
IPPEAIPRGKIYEIYLTVQRKEDL--------------------------------------------------------
---------------------------------------RLPLAGCQTLLGPVVSCGPPGVVLSRPVILSMDHCSDGCLD
--NWALRLKKQN------------------YEGVWE--------------------------------------------
-------------------------------DVLLMGEEL------------VSEPYYCQLEAETCRLFSEQLGT-FALV
GES---LHMG-AAKRLRLVLFSD-AYCSTLEYNIRVY---------------CMDDTQEVFKE-VMQMERQLG-------
------------------------------------------------------------------------------GR
LIDEPH---ILLFKDSYHNLRLSIHDMPQAHWRSKLLAGY-QEIPFYHIWNG-SQRYLHCTFTLERLSLSTCELT-----
--------------------------------------------------------------------------------
---------------------------------------------------------CQLCVWQVEGEGQSFSLDFNIAK
VTARALASSHGV--------------------DTRAIDAEFMLMDSSASALAGPSAFQIPYLIRQKICSSLDAPCPNG--
-ADWRMLAQRLKLE----RHMSFFASKAS----PTSVILDLWEAQHFHS---------GNINQLAAVMADIGKQEAMIFL
-----------VSDGEC---------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------
>Tetraodon_nigroviridis_UNC5A_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------LP-----------------------------------------
---------------------------VMQVTIDITRQQVEKIFG--LDQYWCQCVAWST--TGTQKSQK----------
--------------------------------------------------------------------------------
------------------------------------------------------AYIRIAYLRKN---------------
---FEEEPQGKEVALDQEVLLRCHPPEGVPQAEVEWQRNEDILNPEMDPNFFITADH-----------------------
------------------------------------------------------------------NLIIRKARMADTGN
YTCVAKNIVARRKSTSA------------------AVIVY--------------------------------------VN
GGWST-WTTWSSCSAV---------------CGRGWQKRSRSCTNPTPLNGGSSCDGQNVQKSVCVATCP----------
--------------------------------------------------------------------------------
------------------------------VDGGWSEWSKWSACGADCSM------------------------------
--------------------------------------------------------------------------------
----------WRSRECTQPSPGTGGK---DCQGLDLQSLNCTSEQCPQTFQGF----LSAHHRRQR-----QCEVAAVSG
AEDVALYVG----VVAVALCLTLLLIIVVLVYRRKKEGL-----------------------------------------
----------DADVADSS----ILTTG-FQPMGIKPSKPENS-------------------------------HLLTIQP
DLTTTTTSYQGTLRSRH-----DT-TGKFAMTNGTLLD------------------------------------------
--------------------------------------------------------------------------------
-ALPNGSHTLHNGKLNS-----------DPSEFVSR--------------------------------------------
--LSTQS-------YFKTLPRDVANASYGTFNFLG----------------------GRLTIPNT---------------
---------------------------------------------------------------------------GISLL
IPPEAIPRGKIYEIYLTVQRREDL--------------------------------------------------------
---------------------------------------RLPLAGCQTLLGPVVSCGPPGVVLSRSVILSMDHCSDGCLD
--NWALRLKKQN------------------YEGVWE--------------------------------------------
-------------------------------DVLLMGEEL------------VSEPYYCQLEAETCRLFSEQLGT-FALV
GES---LHMG-AAKRLRLVLFSD-AYCSTLEYNIRVY---------------CMDDTEEVFKE-VMQMERQLG-------
------------------------------------------------------------------------------GR
LIDEPH---ILLFKDSYHNLRLSIHDMPQAHWRSKLLAGY-QEIPFYHIWNG-SQRYLHCTFTLERLSLSTCELT-----
--------------------------------------------------------------------------------
---------------------------------------------------------CQLCVWQVEGEGQSFSLDFNIAK
--------------------------------DTRAIDAEFMLMDSNATALAGPSAFQIPYLIRQKICSSLDAPCPNG--
-ADWRMLAQRLKLE----RHMSFFASKSS----PTSVILDLWEAQHFHS---------GNINQLAAVMADIGKQEAMIFL
-----------VSDGEC---------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------
>Gasterosteus_aculeatus_UNC5A_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------TLPAAF------SDLLPHFLVEPEDEFIVKNKPV
TLTCRSSPATQIYFKCNGEWVHQDDHLIERTVDPATALP-----------------------------------------
---------------------------IMQVTIDITRQQVEKIFG--LDEYWCQCVAWST--TGTQKSQK----------
--------------------------------------------------------------------------------
------------------------------------------------------AYIRIAYLRKN---------------
---FEEEPQGKEVALDQEVLLRCHPPEGVPQAEVEWQRNEDVITPASDPNVFITTDY-----------------------
------------------------------------------------------------------NLVIKKARLADTGN
YTCVAKNIVARRKSTSA------------------TVLVY--------------------------------------VN
GGWST-WTTWSSCSAV---------------CGRGWQKRSRSCTNPTPLNGGTSCEGQNVQKSACVATCP----------
--------------------------------------------------------------------------------
------------------------------VDGGWSEWSKWSACGADCSM------------------------------
--------------------------------------------------------------------------------
----------WRSRECTQPSPGTGGK---DCQGLDLQSLNCTSEQCPQIVLIL----IFLPSHPPP-----PLP-SAVSG
AEDVALYVG----MVAVALCLTLLLIVVVLVYRRKKEDL-----------------------------------------
----------DADVADSS----ILTTG-FQPMGIKP---KNS-------------------------------HLLTIQP
DLTTTTTSYQGTLRSRH-----DT-TGKFSMTNGPLLD------------------------------------------
--------------------------------------------------------------------------------
-PLPNGSHTLHNGKLNS-----------DPAEFVSR--------------------------------------------
--LSTQS-------YFKTLPRDVANSSYGTFNFLG----------------------GRLTIPST---------------
---------------------------------------------------------------------------GISLL
IPPEAIPRGKIYEIYLTVQRKEDL--------------------------------------------------------
---------------------------------------RLPLAGCQTLLSPVVSCGPPGVVLSRPVILSMDHCSDACLD
--NWAIRLKKQN------------------YEGTWE--------------------------------------------
-------------------------------DVLLMGEEL------------VSEPYYCQLEAETCRLFSEQLGT-LALV
GES---LHMG-AAKRLRLVLFSD-AYCSTLEYNIRVY---------------CMDDTQDVFKE-VMQMERQLG-------
------------------------------------------------------------------------------GR
LIDEPH---VLLFKDSYHNLRLSIHDMPQAHWRSKLLAGY-QEIPFYHIWNG-SQRYLHCTFTLERLSLSTCELT-----
--------------------------------------------------------------------------------
---------------------------------------------------------CQLCVWQVEGEGQSFSLDFNIAK
--------------------------------VTLAIRIPLLEPDSTAAALAGPSAFQIPYLIRQKICSSLDAPCPNG--
-ADWRMLAQRLKLES---RHMSFFASKAS----PTSVILDLWEAQHFHS---------GNINQLATVMADIGKQEAMIFL
-----------VSDGEC---------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------
>Oryzias_latipes_UNC5A_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------RSYRGARGAAKSFLFMCHWRKSNNSKNVKSSEYAATAALPAAF------SDRLPHFLVEPEDKYIVKNKPV
TLTCRSTPATQIYFKCNGEWVHQDDHYIEHSVDPATGLP-----------------------------------------
---------------------------VMWVTIDITRQQVEKIFG--LDEYWCQCVAWST--TGTQKSQK----------
--------------------------------------------------------------------------------
------------------------------------------------------AYIRIAYLRKN---------------
---FEEEPQSKEVALDQEVSLRCHPPEGVPPAEVEWQRNEDLVDPTSDPNFVITPDH-----------------------
------------------------------------------------------------------NLVIKAARLADTGN
YTCVAKNIVARRKSNSA------------------TVLVF--------------------------------------VN
GGWST-WTTWSSCSAV---------------CGRGWQKRSRSCTNPTPLNGGTSCEGQNVQKSACVATCP----------
--------------------------------------------------------------------------------
------------------------------VDGGWSEWSKWSACGADCSM------------------------------
--------------------------------------------------------------------------------
----------WRSRECTQPSPGTGGK---DCQGLDLQSLNCTSEQCPQICT------------SLN-----VQQLRAVRG
AEDVALYVG----MVAVALCLTLLLIVVVLVYRRKKEGL-----------------------------------------
----------DADVADSS----ILTTG-FQPMGIKPSKPENS-------------------------------HLLTIQP
DLTTTTTSYQGTLRSRH-----DA-TAKFSMTNGPLLD------------------------------------------
--------------------------------------------------------------------------------
-PLPNGSHTLHNGKLNP-----------DPAEFVSR--------------------------------------------
--FSTQS-------YFKTLPRDVANTSYGTFNFLG----------------------GRLTIPNT---------------
---------------------------------------------------------------------------GISLL
IPPEAIPRGKIYEIYLTVQRKEDL--------------------------------------------------------
---------------------------------------RLPLAGCQTLLSPVVSCGPPGVVLSRPVILSMDHCFDACLD
--NWAVRLKKQN------------------YEGTWE--------------------------------------------
-------------------------------DVLLMGEEL------------VSEPFYCQLEAETCRLFSEQLGT-FAVV
GES---LHMG-AAKRLRLVLFSD-AYCSTLEYNIRVY---------------CMDDTQDVFKE-VMQMERQLG-------
------------------------------------------------------------------------------GR
LIDEPH---VLLFKDSYHNLRLSIHDMPQAHWRSKLLAGY-QEIPFYHIWNG-SQRYLHCTFTLERLSLSTCELT-----
--------------------------------------------------------------------------------
---------------------------------------------------------CQLCVWQVEGEGQSFSLDFNIAK
--------------------------------DTRAVDSEFLVMDSNATALAGPSAFQIPYLIRQKICSSLDAPCPNG--
-ADWRMLAQRLKLE----RHMSFFASKAS----PTSGILDLWEAQHFHS---------GNINQLAAVMADIGKQEAMIFL
-----------VSDGDC---------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------
>Oryzias_latipes_UNC5A_b
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------DDDFAGLGELPETFPSDP------PEPLPVFLMEPEEAYIVKNKPV
NLYCKATPATQIYFKCNSEWVHQKEHTVEERVDENS--------------------------------------------
------------------------GLVVREASIEITRQQVEELFG--PEDFWCQCVAWSS--AGTTKSRK----------
--------------------------------------------------------------------------------
------------------------------------------------------AHVRIAYLRKP---------------
---FDQEPLGKEVSIEQEVLLQCRPPEGIPPAEVEWLKNDEIIDPAEDRNFYITIDH-----------------------
------------------------------------------------------------------NLIIKQARLSDTAN
YTCVAKNIVAKRYSTTA------------------TVIVY--------------------------------------VN
GGWST-WTEWSVCNSR---------------CGRGYQKRTRSCTNPAPLNGGAICDGQGIQKLPCNPLCPGGV-------
--------------------------------------------------------------------------------
-----------------------------IVDGLWTEWSKWSTCGTECTH------------------------------
--------------------------------------------------------------------------------
----------WRRRDCGAPAPKNGGK---DCEGTVLQSKNCTDGLCMQSSLNP----KSSEAKG-----KNDLGNSLAPS
TDDVALYVGI---VIAVIMCLVISVVVALFVYRRNHRDF-----------------------------------------
----------SSDILDSS----ALNGG-FQPVSIKTAR---------------------------------KADLLTAPP
DLTSAAALYRGPVYALH------DVADKIPMTNSPLLE------------------------------------------
--------------------------------------------------------------------------------
-PLPNLKIKVYNSSGLVT-----------PQDDLGGEFSSKLSP----KLP-----------------------HCLLDN
SDSTMGRRTQ---SQTLLRTRDPSCTALGSFS-----SQG-----------------GQLIVP-----------------
-------------------------------------------------------------------------NSGVSLL
IPAGAVPQGRVYEMYVTVQRKENL--------------------------------------------------------
---------------------------------------RPSVEDGQTVLSPVVSCGPPGALLTRPVVITMHHCAVCDGQ
-QDWLIQLKSQS------------------QQNQWE--------------------------------------------
-------------------------------DVVVVGEEN------------FTTPCYVQMDDEACHILTETLGT-YCLV
GQS---LSAA-TIKRLKLAIFGP-VTCAAMEYHIRVY---------------CLDDTQDALKE-VLQMEKQMG-------
------------------------------------------------------------------------------GK
LLDEPK---TLSFKDSTHNLRLSIHDVPHMMWKSKLLAKY-QELSFQQVWSG-SQRNLHCCFTLERFSTSTVDLT-----
--------------------------------------------------------------------------------
---------------------------------------------------------CKICVRQVEGEGQIFQLDTTLSE
DS-----------------------------QSIDTSLLDPA---SNITTLVGPNAFRIPVSIRQKLCSSLDAPQTRG--
-NDWRMLAHKLNLD----RYLNYFATKSS----PTGVILDLWEAQHFPD---------GNLSRLAQVLEEMGRHDSLVPA
-----------VFEH-----------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------
>Homo_sapiens_UNC5B
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
MGARSGAR-GALLLALLLCWDP--------RLSQAGTDSGSEVLPDSFPSAP------AEPLPYFLQEPQDAYIVKNKPV
ELRCRAFPATQIYFKCNGEWVSQNDHVTQEGLDEATGLR-----------------------------------------
---------------------------VREVQIEVSRQQVEELFG--LEDYWCQCVAWSS--AGTTKSRR----------
--------------------------------------------------------------------------------
------------------------------------------------------AYVRIAYLRKN---------------
---FDQEPLGKEVPLDHEVLLQCRPPEGVPVAEVEWLKNEDVIDPTQDTNFLLTIDH-----------------------
------------------------------------------------------------------NLIIRQARLSDTAN
YTCVAKNIVAKRRSTTA------------------TVIVY--------------------------------------VN
GGWSS-WAEWSPCSNR---------------CGRGWQKRTRTCTNPAPLNGGAFCEGQAFQKTACTTICP----------
--------------------------------------------------------------------------------
------------------------------VDGAWTEWSKWSACSTECAH------------------------------
--------------------------------------------------------------------------------
----------WRSRECMAPPPQNGGR---DCSGTLLDSKNCTDGLCMQNK-----------------KTLSDPNSHLLEA
SGDAALYAGL---VVAIFVVVAILMAVGVVVYRRNCRDF-----------------------------------------
----------DTDITDSSA---ALTGG-FHPVNFKTARPSN-----------------------------PQLLHPSVPP
DLTASAGIYRGPVYALQ------DSTDKIPMTNSPLLD------------------------------------------
--------------------------------------------------------------------------------
-PLPSLKVKVYSSSTTGS-----------GPGLADGADLLGVLP----PGTYPS--------------------DFARDT
HFLHLRSASL-GSQQLLGLPRDPGSSVSGTFG-----CLG-----------------GRLSIP-----------------
-------------------------------------------------------------------------GTGVSLL
VPNGAIPQGKFYEMYLLINKAESTLP------------------------------------------------------
-----------------------------------------LSEGTQTVLSPSVTCGPTGLLLCRPVILTMPHCAEVSA-
-RDWIFQLKTQA------------------HQGHWE--------------------------------------------
-------------------------------EVVTLDEET------------LNTPCYCQLEPRACHILLDQLGT-YVFT
GES---YSRS-AVKRLQLAVFAP-ALCTSLEYSLRVY---------------CLEDTPVALKE-VLELERTLG-------
------------------------------------------------------------------------------GY
LVEEPK---PLMFKDSYHNLRLSLHDLPHAHWRSKLLAKY-QEIPFYHIWSG-SQKALHCTFTLERHSLASTELT-----
--------------------------------------------------------------------------------
---------------------------------------------------------CKICVRQVEGEGQIFQLHTTLAE
TPAG----------------------------SLDTLCSAPG---STVTTQLGPYAFKIPLSIRQKICNSLDAPNSRG--
-NDWRMLAQKLSMD----RYLNYFATKAS----PTGVILDLWEALQQDD---------GDLNSLASALEEMGKSEMLVAV
-----------ATDGDC---------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------
>Macaca_mulatta_UNC5B
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
MWTRSGAR-DALLLALLLCWDP--------RLSQAGTDSGSEALPDSFPSAP------AEPLPYFLQEPQDAYIVKNKPV
ELRCRAFPATQIYFKCNGEWVSQNDHVTQEGLDEATGLR-----------------------------------------
---------------------------VREVQIEVSRQQVEELFG--LEDYWCQCVAWSS--AGTTKSRR----------
--------------------------------------------------------------------------------
------------------------------------------------------AYVRIAYLRKN---------------
---FDQEPLGKEVPLDHEVLLQCRPPEGVPVAEVEWLKNEDVIDPTQDTNFLLTIDH-----------------------
------------------------------------------------------------------NLIIRQARLSDTAN
YTCVAKNIVAKRRSTTA------------------TVIVY--------------------------------------VN
GGWSS-WAEWSPCSNR---------------CGRGWQKRTRTCTNPTPLNGGAFCEGQAFQKTACTTICP----------
--------------------------------------------------------------------------------
------------------------------VDGAWTEWSKWSACSTECAH------------------------------
--------------------------------------------------------------------------------
----------WRSRECMAPPPQNGGR---DCSGTLLDSKNCTDGLCMQNK-----------------KTLSDPNSHLLEA
SGDAALYAGL---VVAVFVVVAILMAVGVVVYRRNCRDF-----------------------------------------
----------DTDITDSSA---ALTGG-FHPVNFKTARPNN-----------------------------PQLLHPSVPP
DLTASAGIYRGPVYALQ------DSTDKIPMTNSPLLD------------------------------------------
--------------------------------------------------------------------------------
-PLPSLKVKVYSSSTTGS-----------GPGLADGADLLGVLP----PGTYPS--------------------DFTRDT
HLLHLRSASL-GSQQLLGLPRDPGSSVSGTFG-----CLG-----------------GRLSIP-----------------
-------------------------------------------------------------------------GTGVSLL
VPNGAIPQGKFYEMYLLINKAESTLP------------------------------------------------------
-----------------------------------------LSEGTQTVLSPSVTCGPTGLLLCRPVILTVPHCAKVSV-
-GDWIFQLKTQA------------------HQGHWE--------------------------------------------
-------------------------------EVVTLDEET------------LNTPCYCQLEPRACHILLDQLGT-YVFT
GES---YSRS-AVKRLQLAVFAP-ALCTSLEYSLRVY---------------CLEDTPVALKE-VLDLERTLG-------
------------------------------------------------------------------------------GY
LVEEPK---PLMFKDSYHNLRLSLHDLPHAHWRSKLLAKY-QEIPFYHIWSG-SQKALHCTFTLERHSLASTELT-----
--------------------------------------------------------------------------------
---------------------------------------------------------CKICVRQVEGEGQIFQLHTTLAE
TPAG----------------------------SLDTLCSAPG---SAVTTQLGPYAFKIPLSIRQKICNSLDAPNSRG--
-NDWRMLAQKLSMD----RYLNYFATKAS----PTGVILDLWEALQQDD---------GDLNSLASALEEMGKSEMLVAV
-----------ATDGDC---------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------
>Mus_musculus_UNC5B
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
MRARSGVR-SALLLALLLCWDP--------TPSLAGVDSAGQVLPDSYPSAP------AEQLPYFLLEPQDAYIVKNKPV
ELHCRAFPATQIYFKCNGEWVSQNDHVTQESLDEATGLR-----------------------------------------
---------------------------VREVQIEVSRQQVEELFG--LEDYWCQCVAWSS--SGTTKSRR----------
--------------------------------------------------------------------------------
------------------------------------------------------AYIRIAYLRKN---------------
---FDQEPLAKEVPLDHEVLLQCRPPEGVPVAEVEWLKNEDVIDPAQDTNFLLTIDH-----------------------
------------------------------------------------------------------NLIIRQARLSDTAN
YTCVAKNIVAKRRSTTA------------------TVIVY--------------------------------------VN
GGWSS-WAEWSPCSNR---------------CGRGWQKRTRTCTNPAPLNGGAFCEGQAFQKTACTTVCP----------
--------------------------------------------------------------------------------
------------------------------VDGAWTEWSKWSACSTECAH------------------------------
--------------------------------------------------------------------------------
----------WRSRECMAPPPQNGGR---DCSGTLLDSKNCTDGLCVLNQ-----------------RTLNDPKSHPLET
SGDVALYAGL---VVAVFVVVAVLMAVGVIVYRRNCRDF-----------------------------------------
----------DTDITDSSA---ALTGG-FHPVNFKTARPNN-----------------------------PQLLHPSAPP
DLTASAGIYRGPVYALQ------DSADKIPMTNSPLLD------------------------------------------
--------------------------------------------------------------------------------
-PLPSLKIKVYNSSTIGS-----------GSGLADGADLLGVLP----PGTYPG--------------------DFSRDT
HFLHLRSASL-GSQHLLGLPRDPSSSVSGTFG-----CLG-----------------GRLSLP-----------------
-------------------------------------------------------------------------GTGVSLL
VPNGAIPQGKFYDLYLHINKAESTLP------------------------------------------------------
-----------------------------------------LSEGSQTVLSPSVTCGPTGLLLCRPVVLTVPHCAEVIA-
-GDWIFQLKTQA------------------HQGHWE--------------------------------------------
-------------------------------EVVTLDEET------------LNTPCYCQLEAKSCHILLDQLGT-YVFM
GES---YSRS-AVKRLQLAIFAP-ALCTSLEYSLRVY---------------CLEDTPVALKE-VLELERTLG-------
------------------------------------------------------------------------------GY
LVEEPK---PLLFKDSYHNLRLSLHDIPHAHWRSKLLAKY-QEIPFYHVWNG-SQRALHCTFTLERHSLASTEFT-----
--------------------------------------------------------------------------------
---------------------------------------------------------CKVCVRQVEGEGQIFQLHTTLAE
TPAG----------------------------SLDALCSAPG---NAITTQLGPYAFKIPLSIRQKICSSLDAPNSRG--
-NDWRLLAQKLSMD----RYLNYFATKAS----PTGVILDLWEARQQDD---------GDLNSLASALEEMGKSEMLVAM
-----------ATDGDC---------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------
>Gallus_gallus_UNC5B
--------------------------------------------------------------------------------
-------------------------------------------------------------------------------M
PPARRLLLPFFLLLLLPLHLRWA--------LAAAGLEYS-EVLPDSFPSAP------AETLPHFLREPQDAYIVKNKPV
ELVCRANPATQIYFKCNGEWVNQNDHVTTESLDEVTG-------------------------------------------
------------------------L-LVREVQIEVSRQQVEELFG--LEDYWCQCVAWSS--AGTTKSRR----------
--------------------------------------------------------------------------------
------------------------------------------------------AYVRIAYLRKN---------------
---FDQEPLGKEVPLEQEVLLQCRPPEGVPQAEVEWLRNEDVIDPTQDTNFLITIDH-----------------------
------------------------------------------------------------------NLIIKQARLLDTAN
YTCMAKNIVAKRRSTTA------------------AVIVY--------------------------------------VN
GGWST-WSEWSPCNNR---------------CGRGWQKRTRTCTNPAPLNGGSFCDGQPFQKVTCTTLCP----------
--------------------------------------------------------------------------------
------------------------------VDGAWTEWSKWSACSTECTH------------------------------
--------------------------------------------------------------------------------
----------WRSRECSAPAPRNGGK---DCSGGLLDSKNCTDGLCLHNK-----------------RVLSEPKSHLLEA
TGDVALYAGL---VVAIFVFIVILMAVGVVVYRRRCRDF-----------------------------------------
----------DTDITDSSA---ALTGG-FHPVNFKTARH-DN----------------------------PQLLHPSMQP
DLTANAGVYRGPMYALQ------DSSDKIPMTNSPLLD------------------------------------------
--------------------------------------------------------------------------------
-PLPNLKIKVYNSSTTSS-----------SPGLHDGTDLLGGIPA---VGTFPG--------------------DSS--S
QFVNMRNKAQQGSQHLLSLPREHGTSASGTFS-----YLG-----------------GRLTIP-----------------
-------------------------------------------------------------------------GTGVSLL
VPHGAIPQGKFYEIYLVINKAESGLLP-----------------------------------------------------
------------------------------------------SEGTQTVLSPAVTCGPTGLLLCRPVVLTIPHCADVSS-
-SDWIFQLKTQS------------------HQGNWE--------------------------------------------
-------------------------------EVVTLDEET------------LNTPCYCQLEAKSCHVLLDQLGT-YVFV
GES---YSRS-AIKRLQLAIFAP-AICTSLEYSLKVY---------------CLEDTPDALKE-VLELERTLG-------
------------------------------------------------------------------------------GY
LLEEPK---PLPFKDSYHNLRLSIHDIPHSLWRSKLLAKY-QEIPFYHIWSG-SQRALHCTFTLERYSQASTELT-----
--------------------------------------------------------------------------------
---------------------------------------------------------CKICVRQVEGEGQIFQLHVTLGE
HAN-----------------------------SFDTLHSHNS---SAPTTQLGPYAFKIPLSIRQKICNSLDAPNSRG--
-NDWRLLAQKLSMD----RYLNYFATKAS----PTGVILDLWEAEHQDD---------GDLNTLASALEEMGKSEMLVVM
-----------ATEGDC---------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------
>Xenopus_tropicalis_UNC5B
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------GIEYS-DVLPDSFPSAP------AESLPHFLLEPEDAYIVKNKPV
ELVCKANPATQIYFKCNGEWVNQNDHITKERVDEVTASLG----------------------------------------
------------------------L-VVREVQIEVSRQQVEELFG--LEDYWCQCVAWSS--AGTTKSKR----------
--------------------------------------------------------------------------------
------------------------------------------------------AYVRIAYLRKN---------------
---FDQEPLGKEVALEQEALLQCRPPEGVPPAEVEWLKNEEIIDPTKDTNFLITIDH-----------------------
------------------------------------------------------------------NLIIKQARLSDTAN
YTCVAKNIVAKRRSTTA------------------TVIVF--------------------------------------VN
GGWSS-WTEWSPCNNR---------------CGHGWQKRTRTCTNPAPLNGGTMCEGQQYQKFACNTMCP----------
--------------------------------------------------------------------------------
------------------------------VDGGWTAWSKWSACSTECTH------------------------------
--------------------------------------------------------------------------------
----------WRSRECNAPTPKNGGK---DCSGMLLDSKNCTDGLCMQNK-----------------RVLGETKSHLLES
TGDVALYAGL---VVAIFIVIILLMAVGIVVYRRNCREL-----------------------------------------
----------DTDITDSSA---ALTGG-FHPVNFKTSRHADN----------------------------SHLIHPAMQP
DLTANAGIYRGHMYALQ------DSADKIPMTNSPLLD------------------------------------------
--------------------------------------------------------------------------------
-PLPNLKIKVFNSSTVGS-----------SPGIHDGNDLLGVKP----TGTYPS--------------------DNN---
-IMNARNKNM-STQHLLTLPRDSSNSVTGTFG-----SLG-----------------GRLTFPNT---------------
-------------------------------------------------------------------------ATGVSLL
IPQGAIPQGKYYEMYLMINKRENTVLP-----------------------------------------------------
------------------------------------------SEGTQTILSPIITCGPTGLLLCKPVILTVPHCADIAT-
-SDWILQLKTQS------------------HQGNWE--------------------------------------------
-------------------------------EVVTLNEET------------LNTPCYCQLESHSCHILLDQLGT-YAFV
GES---YSKS-AIKRLQLAIFAP-MLCTSLEYNLKVY---------------CVEDTPDALKE-VLELEKTLG-------
------------------------------------------------------------------------------GY
LVEDPK---PLMFKDSYHNLRLSIHDIPHSLWRSKLLAKY-QEIPFYHIWSG-SQRTLHCTFTLERYSLAATELT-----
--------------------------------------------------------------------------------
---------------------------------------------------------CKICVRQVEGEGQIFQLHTSLEE
NVK-----------------------------SFDPFCSHTEN---SVTTQLGPYAFKIPYSIRQKICNSLDAPNSRG--
-NDWRLLAQKLCMD----RYLNYFATKAS----PTGVILDLWEALHQDD---------GDLNTLASALEEMGKSEMMLVM
-----------ATDGDC---------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------
>Danio_rerio_UNC5B_a
--------------------------------------------------------------------------------
------------------------------------------------------------------------------ML
STWIHRDQSPASLLGLLLLSSTL--------VIHADGSDYSEVLPDSFPSAP------AEPLPEFQSEPEDAFIVKNRPV
KLSCKAAPATQIYFKCNGEWVNQNDHVTKESLDHITGLV-----------------------------------------
---------------------------VREVDISVSRTQVEELFG--LEDYWCQCVAWSS--AGTTKSRR----------
--------------------------------------------------------------------------------
------------------------------------------------------AYVRIAYLRKN---------------
---FEQEPLGREVRLEQEVLLQCRPPEGSPPAEVDWLKNEELIDPALDSNFLITIEH-----------------------
------------------------------------------------------------------DLIIKQARLSDTAN
YTCVARNVVAKRRSSTA------------------TLIVY--------------------------------------VS
GGWSS-WTEWSECNAQ---------------CGRGWQRRTRSCTNPAPLNGGAFCDGPPFQRVTCTTLCP----------
--------------------------------------------------------------------------------
------------------------------VDGGWTEWAKWSACGTECTH------------------------------
--------------------------------------------------------------------------------
----------WRSRECQAPPPRNGGR---HCSGSMMESKNCTEGLCARNK-----------------KVSVEHTSHPLGS
GTGVAVYAGL---VGALLLCVILVLCVGILVYRRSCRHL-----------------------------------------
----------HGEITDSSS---ALTAA-FHPGNYKPPRQDN-----------------------------PHLLHPTAPP
DLTASAGTFRGPLFSLQQA--TLDSHHKIPMTTSPLLD------------------------------------------
--------------------------------------------------------------------------------
-PLPSLKIKVYNSSTMSS-----------LELPTGLGSVDGDIM------------------------------------
SLKTVGSGPK--DHHGHTLPREPSHSASATLG-----SLG-----------------GRLTIP-----------------
-------------------------------------------------------------------------NTGVSLL
VPPGTIPQGKFYEMYLIINKWEKTTLP-----------------------------------------------------
------------------------------------------SDGSQTVLSPVVSCGPSGMLLSRPVVLTLPHCAQLEP-
-PDWTLTLKMQN------------------HQGAWE--------------------------------------------
-------------------------------EVLTVGEES------------LSSPCYLQVEEQSCHILMEQLGT-YGLV
GQS---APPRPACKRLQLALFAPRAPCLSLDYSLRVY---------------CIQDTPHALKE-VLEVERSLG-------
------------------------------------------------------------------------------GV
LLEDPK---PLLFKDSYHNMRLSIHDIPHSHWRSKLLAKY-QEIPFYHIWSG-SQRPLHCTFSLERGSLVVSQLT-----
--------------------------------------------------------------------------------
---------------------------------------------------------CKICVRQVEGEGQIFQLNTDIQE
--------------------------------TLPPHSPLPAGGSCLPSSQVGPYAFRLPVSIRQKICASLDAPSARG--
-CDWRMLARSLAFD----RYLNYFATKPS----PTGVLLDLWEACHQGD---------ADLVSLATALEEMGKSEVLVVM
-----------TTDGDC---------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------
>Takifugu_rubripes_UNC5B_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------SDAEVLPDSFPSAP------AEPLPEFLLEPEDAFIVKNRPV
QLRCRASPATQIYFKCNGEWVNQNDHITRESLDQITGLV-----------------------------------------
---------------------------VREVEISVSRTQVEELFG--LEDYWCQCVAWSS--AGTTKSNR----------
--------------------------------------------------------------------------------
------------------------------------------------------AYVRIAYLRKN---------------
---FEQEPLGREVRLEQEVLLQCRPPEGMPAAEVDWLKNEDAIDPSQDSNFLITIDH-----------------------
------------------------------------------------------------------DLIIKQARLSDTAN
YTCVARNVVAKRRSSTA------------------TLIVYGSCLAVVFKIEFNCRARSHLPSVCPSPS----------VS
GGWSS-WTEWSECNAQ---------------CGRGWQRRTRSCTNPAPLNGGAFCEGPPFQRVTCTTLCP----------
--------------------------------------------------------------------------------
------------------------------VDGGWTEWAKWSACGTECTH------------------------------
--------------------------------------------------------------------------------
----------WRSRECQAPPPRNGGK---HCSGSMMESKNCTEGLCARYK-----------------KVSIEHASHPLAP
DTGVAVYAGL---VGALLLCVILVLCVGVLAYRRRCRHL-----------------------------------------
----------HGDITDSSS---ALTAA-FHPGNYKPSRQDN-----------------------------PNPLHPSAPP
DLTATAGTFRGPLFSLQQG--ANDSPHKIPMTTSPLLD------------------------------------------
--------------------------------------------------------------------------------
-PLPSLKIKVYNSSTLSS-----------LELPADVR-SDGEIL------------------------------------
SLNSVGTVGRERDYYSHTLSREPGLSTSATLG-----NLG-----------------GRLTIP-----------------
-------------------------------------------------------------------------NTGVSLL
VPPGTIPQGKFYEMYLIINKWDKMTLP-----------------------------------------------------
------------------------------------------SEGSQTVLSPVVSCGPSGMLLNRPVVLTLPHCAQLDTP
TPDWTLTLKTQT------------------HQGAWE--------------------------------------------
-------------------------------EVLTVGEET------------LSSPCYLQLEEECCHVLMEQLGT-YGLV
GQS---CPPQPACKRLQLALFAPRAPCLSLDYSLRIY---------------CIHDTPHALKD-VLDLERSLG-------
------------------------------------------------------------------------------GV
LLEDPK---PLLFKDSYHNLRLSIHDIPHTHWRSKLLAKY-QEIPFYHIWSG-SQRPLHCTFSLERSSLAVSQLT-----
--------------------------------------------------------------------------------
---------------------------------------------------------CKICVRQVEGEGQIFQLHTDIQE
VVKRRRCHKILSSAFEKNDALRS-------FQTLPPHSPLPSGGSCPPSSQVGPYAFRLPDSIRQKICASLDVPSARG--
-CDWRLLARSLGFD----RYLNYFATKPS----PTGVLLDLWEACHQAD---------ADLVSLATALEDMGKSEVLVVM
-----------TTDGDC---------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------
>Tetraodon_nigroviridis_UNC5B_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------SEAEVLPDSFPSAP------AEPLPEFLLEPEDAFIVKNRPV
QLRCRASPATQIYFKCNGEWVNQNDHITRESLDQITGLV-----------------------------------------
---------------------------LREVEISVSRTQVEELFG--LEDYWCQCVAWSS--AGTTKSNR----------
--------------------------------------------------------------------------------
------------------------------------------------------AYVRIAYLRKN---------------
---FEQEPLGREVRLEQEVLLQCRPPEGMPAAEVDWLKNEDVIDPSQDSNFLITIDH-----------------------
------------------------------------------------------------------DLIIKQARLSDTAN
YTCVARNVVAKRRSSTA------------------TLIVY--------------------------------------VS
GGWSS-WTEWSECNAQ---------------CGRGWQRRTRSCTNPAPLNGGAFCEGPPFQRVTCTTLCP----------
--------------------------------------------------------------------------------
------------------------------VDGGWTEWAKWSACGTECTH------------------------------
--------------------------------------------------------------------------------
----------WRSRECQAPSPRNGGK---HCSGSMMESKNCTEGLCAR----------------------------SLAP
DTGVAVYAGL---VGALLLCVILVLCVGVLAYRRRCRHL-----------------------------------------
----------HGDITDSSS---ALTAA-FHPGNYKPSRQDN-----------------------------PNPLHPSAPP
DLTATAGTFRGPLFSLQQG--VNDSPHKIPMTTSPLLD------------------------------------------
--------------------------------------------------------------------------------
-PLPSLKIKVYNSSTLSS-----------LELPADVC-SDGEIL------------------------------------
SLKSVGTVGRERDCYGHTLSREPGLSTSATLG-----NLG-----------------GRLTIP-----------------
-------------------------------------------------------------------------NTGVSLL
VPPGTIPQGKFYEMYLIINKWDKMTLP-----------------------------------------------------
------------------------------------------SEGSQTVLSPVVSCGPSGMLLNRPVVLTLPHCAQLDSP
TPDWTLTLKTQT------------------HQGAWE--------------------------------------------
-------------------------------EVLTVGEET------------LSSPCYLQLEEECCHLLMEQLGT-YGLV
GQS---CPPQPACKRLQLALFAPRAPCLSLDYSLRIY---------------CIHDTPHALKE-VLDLERSLG-------
------------------------------------------------------------------------------GV
LLEDPK---PLPFKDSYHNLRLSIHEIPHTHWRSKLLAKY-QEIPFYHIWSG-SQRPLHCTFSLERSSLAVSQLA-----
--------------------------------------------------------------------------------
---------------------------------------------------------CKICVRQVEGEGQIFQLHTDIQE
--------------------------------TLPPHSPLPSGGSCLPSSQVGPYAFRLPDSIRQKICASLDAPSARG--
-CDWRLLARSLGFD----RYLNYFATKPS----PTGVLLDLWEACHQGD---------ADLVSLATALEEMGKSEVLVVM
-----------TTDGDC---------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------
>Gasterosteus_aculeatus_UNC5B_a
--------------------------------------------------------------------------------
-------------------------------------------------------------------------------A
VSYTHILPFGCLFISYLSNSWVT--------AKE