>Homo_sapiens_TSPAN5
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------MSGK
HYKG-------------------------------PEVSCCIKYFIFGFN---VIFWFL--------------------G
-ITFLGIGLWAWNEKGVL--SNISSITDLGG------FDPVWLF---LVVGGVMF-ILGFAGCIGALRENTFLLKFF---
-SVFLGIIFFLELTAG--VLAFVFKD---WIKDQLY-FFINNNIRAYRDDIDLQNL-----------------IDFTQEY
--WQCCG----------AFGADDWN----LNIYFNC--TDSNA------------SRERCGVPFSCCTKDPAED------
VINTQCGYDAR------------------QKPEVDQQIVIYTKGCVP-QFEKWLQDNLTIVAGIFIG---IALL---QIF
G-----------------ICLAQNLVSDIE---------AVRA----SW-------------------------------
--------------------------------------------------------------------------------
-----
>Mus_musculus_TSPAN5
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------MSGK
HYKG-------------------------------PEVSCCIKYFIFGFN---VIFWFL--------------------G
-ITFLGIGLWAWNEKGVL--SNISSITDLGG------FDPVWLF---LVVGGVMF-ILGFAGCIGALRENTFLLKFF---
-SVFLGIIFFLELTAG--VLAFVFKD---WIKDQLY-FFINNNIRAYRDDIDLQNL-----------------IDFTQEY
--WQCCG----------AFGADDWN----LNIYFNC--TDSNA------------SRERCGVPFSCCTKDPAED------
VINTQCGYDAR------------------QKPEVDQQIVIYTKGCVP-QFEKWLQDNLTIVAGIFIG---IALL---QIF
G-----------------ICLAQNLVSDIE---------AVRA----SW-------------------------------
--------------------------------------------------------------------------------
-----
>Rattus_norvegicus_TSPAN5
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------MSGK
HYKG-------------------------------PEVSCCIKYFIFGFN---VIFWFL--------------------G
-ITFLGIGLWAWNEKGVL--SNISSITDLGG------FDPVWLF---LVVGGVMF-ILGFAGCIGALRENTFLLKFF---
-SVFLGIIFFLELTAG--VLAFVFKD---WIKDQLY-FFINNNIRAYRDDIDLQNL-----------------IDFTQEY
--WQCCG----------AFGADDWN----LNIYFNC--TDSNA------------SRERCGVPFSCCTKDPAED------
VINTQCGYDAR------------------QKPEVDQQIVIYTKGCVP-QFEKWLQDNLTIVAGIFIG---IALL---QIF
G-----------------ICLAQNLVSDIE---------AVRA----SW-------------------------------
--------------------------------------------------------------------------------
-----
>Xenopus_tropicalis_TSPAN5
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------MSGK
HYKG-------------------------------PEVSCCIKYFIFGFN---VIFWLL--------------------G
-ITFLGVGLWAWSEKGVL--SNISSITDLGG------FDPVWLF---LVVGGVMF-ILGFAGCIGALRENTFLLKFF---
-SVFLGIIFFLELTAG--VLAFVFKD---WIKDQLQ-FFINNNIRAYRDDIDLQNL-----------------IDFTQEY
--WQCCG----------AFGADDWN----LNIYFNC--TDANA------------SRERCGVPFSCCTKDPAED------
VINTQCGYDVR------------------QKPELDQQETIHTKGCVP-QFEKWLQDNLTIVAGVFIG---IALL---QIF
G-----------------ICLAQNLVSDIE---------AVRA----SW-------------------------------
--------------------------------------------------------------------------------
-----
>Danio_rerio_TSPAN5a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------MLAGSFVLEINEPMMTGK
HYKG-------------------------------QEVSCCIKYFIFGFN---IIFWLL--------------------G
-VAFLGIGLWAWSEKGVL--SNISSITDLGG------FDPVWLF---LVVGGVMF-ILGFAGCIGALRENTFLLKFF---
-SVFLGIIFFLELTAG--ILAFVFKD---WIKDQLN-FFINNNIRAYRDDIDLQNL-----------------IDFTQEY
--WECCG----------AFGADDWN----LNIYFNC--TDSNP------------SREKCGVPFSCCTKDPAED------
VINTQCGYDVR------------------AKPDAEQKTYIHVKGCVP-QFEKWLQDNLTVVAGIFIG---IALL---QIF
G-----------------ICLAQNLVSDIE---------AVRA----SCLFT----------------------------
--------------------------------------------------------------------------------
-----
>Takifugu_rubripes_TSPAN5a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------MSGN
HYKG-------------------------------HEVSCCIKYFIFGFN---ILFWLL--------------------G
-MALVGIGLWAWSEKGVL--SNISSITDLGG------LDPVWLF---MVVGGVMF-ILGFAGCIGALRENTFLLKFF---
-SVFLGIIFFLELTTG--VLAFVFKD---WIKDQLN-LFINNNIRAYRDDIDLQNL-----------------IDFTQEY
--WECCG----------AFGADDWN----LNIYFNC--TDGNP------------SREKCGVPFSCCTKDPAED------
VINTQCGYDVR------------------AKPDSEQKDSINVKGCVP-QFEKWLQDNLTLVAGIFIG---VALL---QIF
G-----------------ICLAQNLVSDIE---------AVQA----SCFFT----------------------------
--------------------------------------------------------------------------------
-----
>Takifugu_rubripes_TSPAN5b
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------MSGK
HFKA-------------------------------HEVSCCIKYFIFGFN---VIFWFL--------------------G
-VAFLAIGLWAWSEKGVL--SNISSITDLGG------FDPVWLF---LVVGGVMF-ILGFAGCIGALRENSFLLKFF---
-SVFLGIIFFLELX-------LFFKD---WIKDQLN-FFINNNIRAYRDDIDLQNL-----------------IDFTQEY
--WECCG----------AFGADDWN----LNIYFNC--TDSNP------------SREKCGVPFSCCTKDPGED------
VINTQCGYDIR------------------AKTDSEQRTHIYMKGCVP-QFEKWLQDNLTVVAGIFIG---IALL---QIF
G-----------------ICLAQNLVSDIE---------AVRE----SCLFT----------------------------
--------------------------------------------------------------------------------
-----
>Tetraodon_nigroviridis_TSPAN5a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------PARRPASGQMMPGK
YFKA-------------------------------HEVSCCIKYFIFGFN---IIFWFL--------------------G
-VAFLAIGLWAWSEKGVL--SNISSITDLGG------FDPVWLF---LVVGGVMF-ILGFAGCIGALRENSFLLKFF---
-SVFLGIIFFLELTAG--VLAFVFKD---WIKDQLN-FFINNNIRAYRDDIDLQNL-----------------IDFTQEY
--WECCG----------AFGADDWN----LNIYFNC--TDSNP------------SREKCGVPFSCCTKDPGED------
VINTQCGYDIR------------------AKADSEQRTHIYIKGCVP-QFEKWLQDNLTVVAGIFIG---IALL---QIF
G-----------------ICLAQNLVSDIE---------AVRE----SW-------------------------------
--------------------------------------------------------------------------------
-----
>Gasterosteus_aculeatus_TSPAN5a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------MSGN
QYKG-------------------------------NDVSCCIKYFIFGFN---ILFWLL--------------------G
-MALVGIGLWAWSEKGVL--SNISSITDLGG------LDPVWLF---MVVGGVMF-ILGFAGCIGALRENTFLLKFF---
-SVFLGIIFFLELTTG--VLAFVFKD---WIKDQLN-LFINNNIRAYRDDIDLQNL-----------------IDFTQEY
--WECCG----------AFGADDWN----LNIYFNC--TDGNP------------SREKCGVPFSCCTKDPAED------
VINTQCGYDIF------------------CAKGRQKENVVSLLQARP-AFEKCCRT-TPLVAGISCY---PFLLFHPQIF
G-----------------ICLAQTLVSDIE---------AVQA----SCFFT----------------------------
--------------------------------------------------------------------------------
-----
>Oryzias_latipes_TSPAN5a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------CSNMSGN
PYKGG------------------------------HEVSCCIKYFIFGFN---ILFWLL--------------------G
-MALVGIGIWAWSEKGVL--SNISSITDLGG------LDPVWLF---VVVGGVMF-ILGFAGCIGALRENTFLLKFF---
-SVFLGIIFFLELTAG--ILAFVFKD---WIKDQLN-LFINNNIRAYRDDIDLQNL-----------------IDFTQEY
--WECCG----------AFGVDDWN----LNIYFNC--TDGNP------------SREKCGVPFSCCTKDPAED------
VINTQCGYDIR------------------AKPDSEQKDYINVKGCVP-QFEKWLQDNLTLVAGIFIG---VALL---QIF
G-----------------ICLAQNLVSDIE---------ALIR----LSVTSKKQSDPPWF-------------------
--------------------------------------------------------------------------------
-----
>Oryzias_latipes_TSPAN5b
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------MISGK
HFKA-------------------------------HEVSCCIKYFIFGFN---IIFWFL--------------------G
-VAFLGIGLWAWSEKGVL--SNISSITDLGG------FDPVWLF---LVVGGVMF-ILGFAGCIGALRENSFLLKFF---
-SVFLGIIFFLELTAG--VLAFVFKD---WIKDQLN-FFINNNIRAYRDDIDLQNL-----------------IDFTQEY
--WECCG----------AFGADDWN----LNIYFNC--TDSNP------------SREKCGVPFSCCTKDPAED------
VINTQCGYDIR------------------AKTDSEQRTFIYIKGCVP-QFEKWLQDNLTVVAGIFIG---IALL---QVI
L-----------------V-------------------------------------------------------------
--------------------------------------------------------------------------------
-----
>Ciona_intestinalis_TSPAN5
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----M-----------------------------PQEVGCCTKYFLFSFN---ILFWII--------------------G
-LCLLGAGIWAWSEKGFF--DNLTAISSLP-------IDPVLVV---IIIALVMF-LLSFSGCLGSLRENIFLLKCF---
-SICLGVIFFAELIAG--ILGFVYKD---WFHQQFA-IFVNKTIKGYRDDPDLQNI-----------------IDFSQEY
--LKCCGG---------DTGVADWDN----NIYFDCA-SNISFNDVF------LKPAESCGVPFSCCIKLGTSN------
VVNTQCGYGLRDPG----------------VTASEQVTKIYTSGCIT-QFGDWLKTNLYTVAGVFIG---VALI---QIV
P-----------------ICFAQNLISDIQ---------AVKA----G--------------------------------
--------------------------------------------------------------------------------
-----
>Ciona_savignyi_TSPAN5
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----M-----------------------------PHEIGCCTKYFLFSFN---ILFWII--------------------G
-LCLLGAGIWAWSEKGFF--DNISVISSLP-------IDPVLVL---IIIALVMF-LLSFSGCLGSLRENIFLLKCF---
-SICLGVIFFAELIAG--ILGFVYKD---WFHQQFA-IFVNKTIKGYRDDPDLQNI-----------------IDFSQEY
--LKCCGG---------DTGVSDWDN----NVYFSCT-SRIKFNDVF------LKPAESCGVPFSCCIKENAAD------
VVNTQCGYGLREDS----------------VTVAEQVTRIHTSGCIT-QFGDWLKTNLYTVAGAFIG---VALI---QII
P-----------------ICFAQNLISDIQ---------AVKA----GWLEEKWSRLESMLKEESRLSNAERFTRTAYHP
RSKTARSNSTVSPWYPVQCQEPQLTPVYCNVPHHNRMYVSVPDITMHRRQDSIHGAPVRRSWTSPSCVNVLMHCDDDGTL
LEDYE
>Branchiostoma_floridae_TSPAN5
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------MRHITCNVNN----LS---SLLQLA--------------------G
-GFILGIGLWAWFEKGTF--DNIAKVANVP-------VDPVLIF---VVVGAIMF-ILGFSGCVGALRENIILLRFF---
-SVVLGIIFFVELAVG--VLGFVYKD---WFRQQLD-NFIQANIIHYRDDPDLQNI-----------------IDFVQSY
--FQCCG----------GEDYNDWEN----NIYFNCTLKESRG------------SREACGVPFSCCKDQGNNN------
VLNTQCGYDVREEE--------------INDIKLELDSMNPDQGCVP-QFEAWLQENLFVVAGVAIG---IALL---QVF
G-----------------IYLANSLVSDIQ---------AIQA----LW-------------------------------
--------------------------------------------------------------------------------
-----
>Caenorhabditis_elegans_TSPAN5
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------MANRRQPVQHRAQQR
VYRQSQIRYAPG-------------------AGGESEISCCVKYSVFSFN---VIFFLL--------------------G
-FGLLLFGVWAQIEKNTFV-NMLSKASKLY-------LDPTWPL---LIVGFLTF-IIGFSGCVGSLRENTSFLTFY---
-STLLGLLLIAEFSAG--VFAYACRD---QLDNYIR-NLLNDVVVGYRDDPDLQLL-----------------IDSMQET
--WM-CCG---------INGADDWD----RNTYFSI--EAREVA-----------SPEAGGVPFSCCINSSKLE------
FKNYFCGHGVRLKPESHMAAHL------AAQRVMAHTASIYTEGCLP-KLQLWLNNNMLLVAVSMVI---IAII---QVL
G-----------------ICFAQNLKSDIL---------AQRA----KWYYTH---------------------------
--------------------------------------------------------------------------------
-----
>Homo_sapiens_TSPAN17
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------MPGK
HQHFQ-----------------------------EPEVGCCGKYFLFGFN---IVFWVL--------------------G
-ALFLAIGLWAWGEKGVL--SNISALTDLGG------LDPVWLF---VVVGGVMS-VLGFAGCIGALRENTFLLKFF---
-SVFLGLIFFLELATG--ILAFVFKD---WIRDQLN-LFINNNVKAYRDDIDLQNL-----------------IDFAQEY
--WSCCG----------ARGPNDWN----LNIYFNC--TDLNP------------SRERCGVPFSCCVRDPAED------
VLNTQCGYDVR--LK-------------LVRGELEQQGFIHTKGCVG-QFEKWLQDNLIVVAGVFMG---IALL---QIF
G-----------------ICLAQNLVSDIK---------AVKA----NWSKWNDDFENHWLTPTISEVLSTAGPQQNSLT
GAPGPAPPSRHVFFGLGGLYPEPTFKNW----------------------------------------------------
-----
>Mus_musculus_TSPAN17
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------MPGK
HQQFQ-----------------------------DPEVGCCGKYFLFGFN---IVFWVL--------------------G
-ALFLAIGLWAWGEKGVL--SNISALTDLGG------LDPVWLF---VVVGGVMS-VLGFAGCIGALRENTFLLKFF---
-SVFLGLIFFLELAAG--ILAFVFKD---WIRDQLN-LFINNNVKAYRDDLDLQNL-----------------IDFAQEY
--WSCCG----------ARGPNDWN----LNIYFNC--TDLNP------------SRERCGVPFSCCVRDPAED------
VLNTQCGYDIR--LK-------------LVRRELEQQGSIYTKGCVG-QFEKWLQDNLIVVAGVLVG---IALL---QIF
G-----------------LCLAQNLVSDIK---------AVKA----NW-------------------------------
--------------------------------------------------------------------------------
-----
>Rattus_norvegicus_TSPAN17
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------MPGK
HQQFQ-----------------------------DPEVGCCGKYFLFGFN---IVFWVL--------------------G
-ALFLAIGLWAWGEKGVL--SNISGLTDLGG------LDPVWLF---VVIGGIMS-VLGFAGCIGALRENTFLLKFF---
-SVFLGLIFFLELAAG--ILAFVFKD---WIRDQLN-LFINNNVKAYRDDIDLQNL-----------------IDFAQEY
--WSCCG----------ARGPNDWN----LNIYFNC--TDLNP------------SRERCGVPFSCCVRDPAED------
VLNTQCGYDIR--LK-------------L---ELEQQGSIYTKGCVG-QFEKWLQDNLIVVAGVLVA---IALL---QIC
G-----------------ICLAQNLVSDIE---------AVKA----NW-------------------------------
--------------------------------------------------------------------------------
-----
>Anolis_carolinensis_TSPAN17
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------MPGK
AQHFQ-----------------------------GPQVSCCSKYLLFASN---VLFWLL--------------------G
-AAFLAIGLWAWAEKGVL--SNLSSITDLGG------FDPVWLF---LVVGVVMF-VLGFAGCIGALRENTFLLKFF---
-SVFLGLIFFLELTAG--ILAFIFKD---WIKDQLN-FFINNNVKAYRDDIDLQNL-----------------IDFAQEY
--WSCCG----------AHGPNDWN----LNIYFNC--TDSNP------------SRERCGVPFSCCVKDPAED------
VLNTQCGYDVR--LK-------------L---ELEQQSFIHTKGCAG-QFEKWVQDNLIVVAGTFVG---VALL---QIF
G-----------------ICLAQNLVSDIN---------AVKA----NW-------------------------------
--------------------------------------------------------------------------------
-----
>Xenopus_tropicalis_TSPAN17
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------MSGK
HQHFK-----------------------------GPEVSCCVKYFLFGFN---IVFWLL--------------------G
-AAFLAIGLWAWAEKGVL--SNISSITDLGG------FDPVWLF---IVTGAVMF-VLGFAGCIGALRENTTLLKFF---
-SVFLGLIFFLELTAG--ILAFVFKD---WIKDQLN-FFINNNVKAYRDDIDLQNL-----------------IDFAQEY
--WSCCG----------AHGPNDWN----LNIYFNC--TDSNP------------SRERCGVPFSCCVKDPAED------
VPNTQCGYDVR--LK-------------L---ELEQQSYIYTKGCVG-QFEKWLQDNLIVVAGVFVA---IALL---QIF
G-----------------ICLAQNLVSDIK---------AVKA----NW-------------------------------
--------------------------------------------------------------------------------
-----
>Tetraodon_nigroviridis_TSPAN17a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------MSRK
HHHFR-----------------------------GAEVSCCVKYFLFGFN---ILFWLL--------------------G
-AAFLAIGLWAWKEKGVL--SNLSSITDLGG------FDPVWLF---IVVGGVMF-ILGFAGCIGALRENTFLLKFF---
-SVFLGLIFFLELTAG--ILAFVFKD---WIKDQLN-FFINNNVK-YRDDIDLQNL-----------------IDFAQDY
--WSCCG----------AHGPDDWN----LNIYFNC--TDLNP------------SRERCGVPFSCCVKDPAED------
VINTQCGYDVR--HK-------------V---ELERQKHIYTKGCVG-QFEKWLQDNLIFVAGIFVG---IALL---QIF
G-----------------ICLAQNLVSDVK---------AVKA----NW-------------------------------
--------------------------------------------------------------------------------
-----
>Gasterosteus_aculeatus_TSPAN17b
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------MSRK
HHHLK-----------------------------GAEVSCCVKYFLFGFN---ILFWLL--------------------G
-AAFLAVGLWAWAEK-------------------------------------------------------------F---
-SVFLGLIFFLELTAG--VLAFVFKD---WLKDQLN-FFINNNVKAYRDDIDLQNL-----------------IDFAQEY
--WSCCG----------AHGPDDWD----LNIYFNC--TEPNP------------SRERCGVPFSCCVKDPAED------
VINTQCGYDVR--LQ-------------K---ELDWQKYIHTKGCVG-QFEKWLQDNLIIVAGIFVG---VALL---QIF
G-----------------ICLAQNLVSDVK---------AVKA----NW-------------------------------
--------------------------------------------------------------------------------
-----
>Oryzias_latipes_TSPAN17a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------MSRK
RRHFK-----------------------------GTEVSCCVKYILFGFN---IIFWLL--------------------G
-AAFLSIGLWAWAEKGVL--SNISSITDLGG------LDPVWLF---IVVGGVMF-ILGFAGCIGALRENTVLLKFF---
-SVFLGLIFFLELTTG--ILAYVFKD---WIKDQLN-LFINNNVKAYRDDIDLQNL-----------------IDFAQEY
--WSCCG----------AHGPDDWN----LNMYFNC--TNSNP------------SRERCGVPFSCCVKDPAED------
VINTQCGYDVRRLTK-------------K---DLERQPFIHTKGCVG-QFEKWLQDNLILVAGIFVG---IALL---QIF
G-----------------ICLAQNLVSDIK---------TVKA----NW-------------------------------
--------------------------------------------------------------------------------
-----
>Homo_sapiens_TSPAN14
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------MH
YYRYS-----------------------------NAKVSCWYKYLLFSYN---IIFWLA--------------------G
-VVFLGVGLWAWSEKGVL--SDLTKVTRMHG------IDPVVLV---LMVGVVMF-TLGFAGCVGALRENICLLNFF---
-CGTIVLIFFLELAVA--VLAFLFQD---WVRDRFR-EFFESNIKSYRDDIDLQNL-----------------IDSLQKA
--NQCCG----------AYGPEDWD----LNVYFNC--SGASY------------SREKCGVPFSCCVPDPAQK------
VVNTQCGYDVRIQL------------------KSKWDESIFTKGCIQ-ALESWLPRNIYIVAGVFIA---ISL---LQIF
G-----------------IFLARTLISDIE---------AVKA----GHHF-----------------------------
--------------------------------------------------------------------------------
-----
>Mus_musculus_TSPAN14
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------MH
YYRYS-----------------------------NAEVSCWYKYLLFSYN---IVFWLA--------------------G
-VVFLGVGLWAWSEKGVL--SDLTKVTRLHG------IDPVVLV---LMVGVVMF-TLGFAGCVGALRENICLLKFF---
-CGAIVLIFFLELAVA--VLAFLFQD---WVRDRFR-EFFESNIKSYRDDIDLQNL-----------------IDSLQKA
--NQCCG----------AYGPEDWD----LNVYFNC--SGASY------------SREKCGVPFSCCVPDPAQK------
VVNTQCGYDVRIQL------------------KSKWDEFIFTKGCIQ-ALEGWLPRNIYIVAGVFIA---ISL---LQIF
G-----------------IFLARTLISDIE---------AVKA----GHHF-----------------------------
--------------------------------------------------------------------------------
-----
>Rattus_norvegicus_TSPAN14
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------MH
YYRYS-----------------------------NAEVSCWYKYLLFSYN---IVFWLA--------------------G
-VVFLGVGLWAWSEKGVL--SDLTKVTRLHG------IDPVVLV---LMVGVVMF-TLGFAGCVGALRENICLLKFF---
-CGAIVLIFFLELAVA--VLAFLFQD---WVRDRFR-EFFESNIRSYRDDIDLQNL-----------------IDSLQKA
--NQCCG----------AYGPEDWD----LNVYFNC--SGASY------------SREKCGVPFSCCVPDPAQK------
VVNTQCGYDVRIQL------------------KSKWDEFIFTKGCIQ-ALEGWLPRNIYIVAGVFIA---ISL---LQIF
G-----------------IFLARTLISDIE---------AVKA----GHHF-----------------------------
--------------------------------------------------------------------------------
-----
>Gallus_gallus_TSPAN14
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------MH
YYRYS-----------------------------NAEVSCWYKYLLFSYN---IVFWLA--------------------G
-MAFLAAGLWAWSEKGVL--SDLTKVTGLHG------LDPVVLV---LVVGIVMF-TLGFAGCVGALRENICLLKFF---
-CGTIVLIFLLEVAVA--VLAVLFQD---WVRDKVK-EFFENNIKSYRDDIDLQNL-----------------IDSLQKI
--NHCCG----------AQGPDDWD----FNIYFNC--SSESK------------SREKCGVPFSCCVPDPAQK------
VVNTQCGYDVRKKS------------------KSHWDDQIFIKGCIV-ALEAWLPRNIYVVAGVFIA---ISL---LQIF
G-----------------IFLARTLISDIE---------AVKA----GNAF-----------------------------
--------------------------------------------------------------------------------
-----
>Danio_rerio_TSPAN14a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------MH
YYRYE-----------------------------NAEVSCCYKYLMFSYN---IIFWLA--------------------G
-SAFIAIGFWAWSEKGVL--SDLTQVTRLHG------FDPVWGV---LVVGTVTF-ILGFAGCVGALRENICLLKFF---
-SGVIGFIFFLELTAA--VLAFVFQG---QVREWIS-EFFLANVKAYRDDIDLQNL-----------------IDSLQKL
--NHCCG----------AKHPNDWN----MNVYFNCS-NKNNL------------SREKCGVPFSCCISDPAVT------
VLNTQCGYDVREKGT-----------------LNDWSSSIYIKGCID-ALEDWLPRNLYIVAGVFIV---ISL---LQMV
G-----------------IFLARTLIGDIE---------KVKF----NYY------------------------------
--------------------------------------------------------------------------------
-----
>Takifugu_rubripes_TSPAN14a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------MY
YYRYG-----------------------------TTEVSCCYKYLMFSYN---IIFWLA--------------------G
-AAFIAIGFWAWSEKGIL--RDLTQVTQLHG------FDPVWLV---LLVGGVTF-TLGFAGCVGALRENICLLKFF---
-SGLIGLIFVLEMTVA--VLAIVFQS---QVREWIN-EFFIVNIRAYRDDIDLQNL-----------------IDSLQKM
--NHCCG----------AQEPDDWN----QNVYFRC--NETHL------------SREKCGVPFSCCIPDPADT------
VVNTQCGYDIRKKL------------------KPDWEKHIYMKGCIA-ALEDWLPRNLYMLAVVFII---ISL---LQMV
G-----------------IYLARTLISDIE---------KVKS----AFYSF----------------------------
--------------------------------------------------------------------------------
-----
>Tetraodon_nigroviridis_TSPAN14a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------MY
YYRYE-----------------------------NAEVSCCYKYLMFTYN---IIFWLA--------------------G
-AAFIAIGFWAWSEKGIL--MDLTKVTQLHG------FDPVWLV---LLVGGITF-TLGFAGCVGALRENICLLKFF---
-TGLIGLIFILELTVA--VLAVVFQS---QVKEWFS-EFFLDNIRGYRDDSDLQNL-----------------IDSLQKM
--NHCCG----------AREPDDWD----HNVYFGC--NETNL------------SRKKCGVPFSCCIFDPADT------
VVNSQCGYDVRKKP------------------KAEWANHIYTKGCIA-ALEDWLPRNLYTVAIVFVV---ISL---LQMV
G-----------------IYLAKTLISDIE---------KVK-----ACDNF----------------------------
--------------------------------------------------------------------------------
-----
>Gasterosteus_aculeatus_TSPAN14a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------MY
YYRYE-----------------------------SAEVSCCYKYLMFSYN---IIFWLA--------------------G
-VAFIAVGFWAWSEKGVL--LDLTQVTQLHG------FDPVWLV---LVVGGVTF-ILGFAGCVGALRENICLLKFF---
-SGVIGFIFLLELTAA--VLAVVFQS---QVREWIN-DFFLANVKGYRDDIDLQNL-----------------IDSLQRM
--NHCCG----------AQGPNDWN----QNVYFSC--NGTHR------------SREKCGVPFSCCITDPADS------
VLNSQCGYDVRNRP------------------TSEWTEHIYTKGCIA-ALEDWLPGNLYTVAIVFIV---ISL---LQMV
G-----------------IYLARTLISDIE---------KVNF----SY-------------------------------
--------------------------------------------------------------------------------
-----
>Oryzias_latipes_TSPAN14a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------LKNAPHFPNMY
YYRYE-----------------------------NSEVSCCYKYLMFSYN---IIFWLA--------------------G
-AAFIAAGFWAWSEK------DLTQVTRLHG------FDPVWLV---LVVGGITF-ILGFAGCVGALRENICLLKFF---
-SGVIGLIFFLELTAA--VLAVVFQS---QVREWIN-DFFLQNIRSYRDDIDLQNL-----------------IDSLQKM
--NQCCG----------AKDPNDWD----ENLYFNC--NMTNR------------SRESCGVPFSCCISDPTDL------
VINTQCGYDVRKK-------------------KDDWANYIHTKGCIT-ALEDWLPRNLYTVAIVFVV---ISL---LQMV
G-----------------IYLAKTLISDIHKYCNLKIFSKKKR----RNYWY----------------------------
--------------------------------------------------------------------------------
-----
>Homo_sapiens_TSPAN15
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------MPRGDSEQVRY
CARFS---------------------------------YLWLKFSLIIYS---TVFWL---------------------I
GALVLSVGIYAEVERQ--------KYKTLES----AFLAPAIIL---ILLGVVMF-MVSFIGVLASLRDNLYLLQAF---
-MYILGICLIMELIGG--VVALTFRN----QTIDFLNDNIRRGIENYYDDLDFKNI-----------------MDFVQKK
--FKCCGG--------EDYRDWSKN------QYHDCS--APGP--------------LACGVPYTCCIRN-T-----TE-
VVNTMCGYKTI------------------DKERFSVQDVIYVRGCTN-AVIIWFMDNYTIMAGILLG-ILLPQFLG----
------------------VLLTLLYITRVE--------DIIMEHS-VTDGLLG-PGAKPSVEAAG--TGCCLCYPN----
--------------------------------------------------------------------------------
-----
>Mus_musculus_TSPAN15
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------MPRGDSEQVRY
CARFS---------------------------------YLWLKFSLIIYS---TVFWL---------------------I
GGLVLSVGIYAEAERQ--------KYKTLES----AFLAPAIIL---ILLGVVMF-IVSFIGVLASLRDNLCLLQSF---
-MYILGICLVMELIGG--IVALIFRN----QTIDFLNDNIRRGIENYYDDLDFKNI-----------------MDFVQKK
--FKCCGG--------EDYRDWSKN------QYHDCS--APGP--------------LACGVPYTCCIRN-T-----TD-
VVNTMCGYKTI------------------DKERLNAQNIIHVRGCTN-AVLIWFMDNYTIMAGLLLG-ILLPQFLG----
------------------VLLTLLYITRVE--------DIILEHS-VTDGLLG-PGAKSRTDTAG--TGCCLCYPD----
--------------------------------------------------------------------------------
-----
>Rattus_norvegicus_TSPAN15
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------MPRGDSEQVRY
CARFS---------------------------------YLSLKFSLIIYS---TVFWL---------------------I
GGLVLSVGIYAEAERQ--------KYKTLES----AFLAPAIIL---ILLGVVMF-IVSFIGVLASLRDNLCLLQSF---
-MFILGLCLVMELIGG--IVALIFRN----QTIDFLNDNIRRGIENYYDDLDFKNI-----------------MDFVQKK
--VTGAAGY-------EGQRGTSRT------LALDRV--LPIP--------------GHIPTPWLFCKRR-V-----TD-
VVNTMCGYKTI------------------DKERLNAQNIIHVRGCTN-AVLIWFMDNYSIMAGLLLG-ILLPQFLG----
------------------VLLTLLYITRVE--------DIILEHS-VTDGLLG-PGAKSSTDTAG--TGCCLCYPD----
--------------------------------------------------------------------------------
-----
>Gallus_gallus_TSPAN15
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------MATGDAEQARY
CARLS---------------------------------YLCLKFSLITYC---TAFWV---------------------I
GGLVLAVGIYAEVERQ--------KYKTLES----AFLAPAIIL---ILLGIIMF-FVSFVGVLASLRDNLCLLQAF---
-MYILGLCLMIELAGA--VVALIFRN----QTIKFLNDNIRRGIENYYDDLDFKNI-----------------MDSVQKR
--FKCCGG--------EDYTDWSKN------AYHDCA--APGP--------------LACGVPYTCCVRN-K-----TD-
IINTMCGYKTI------------------DQERLSIQDVIYIRGCTN-AVLIWFLDNYSIMAGVLLG-ILLPQFLG----
------------------VLLSLLYITRVE--------DIIAEHK-LGESLFGGTRQHPDPEFAS--PGCCMCYPG----
--------------------------------------------------------------------------------
-----
>Anolis_carolinensis_TSPAN15
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------RMAAGDSEQVRY
CARFS---------------------------------YLCLKFSLVTYS---TVFWL---------------------L
GAFVLAVGIYAEVERQ--------KYKTLES----AFLAPAIIL---ILLGIVMF-LVSFVGVLASLRDNLSLLQAF---
-MYILGICLLIELTGG--VMALIFRH----KTIDFVNDNIRRGIVNYYDDLDFKNI-----------------MDFVQEE
--FKCCGG--------EDFKDWSIN------QYHACS--APGP--------------MACGVPYSCCITN-K-----TA-
VINTMCGYNTI------------------DKERLSVQPFIHVRGCTN-AVLIWFLDNYAIMAGILLG-ILLPQFLG----
------------------VVLTFLYISRVE--------DIITEHK-QNETLLDGGRQKMDVEFAG--AGCCMCFPA----
--------------------------------------------------------------------------------
-----
>Danio_rerio_TSPAN15a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------MTGEVRY
CEKCS---------------------------------YFFLKFSLIGYA---TIFWL---------------------I
GGFILAIGIYAEVERQ--------RYKTLEG----VFLAPAIIL---IVLGIIMF-IVSFIGVLASLRDNLCLLKVF---
-LYMLALCLVLELVGG--IVALIFKN----QTVDILNKNIRKGMVNYYDDLDFKNI-----------------MDFVQKT
--FKCCGG--------TEYQDWEVN------MYHNCS--APGP--------------LACAAPYTCCIVT-P-----GE-
VVNTMCGYKTL------------------NKERNENTNVIYIRGCTD-AVFIWLIDNYKTMAGLLLG-IFLPQFFG----
------------------VIFTWLYITRVE--------DAIEEYGYYMDGLLQSDSVQPETKRQSKLAKCCKCMPLMD--
--------------------------------------------------------------------------------
-----
>Takifugu_rubripes_TSPAN15a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------NNGDIRY
CHKFS---------------------------------YVFLKFLLFFYA---IVFWL---------------------I
GGFILAVGIYAEVERQ--------RYKTLEG----VFLAPAIIL---ILLGVVMF-IVSFIGVLASLRDNLTLLKVF---
-MYTLAVCLILELLGG--VVALLFRN----QTVELLNKNIRKGIVNYYDDLDFKNI-----------------MDFVQQK
--FKCCGG--------QEYKDWSVN------MYHNCS--APGP--------------LACGVPYTCCITTNP-----NE-
VANSFCGYKVL------------------NKERLDLIEVIYTRGCTD-AFFIWLTDNYKIMAGLMLG-ILLPQFLG----
------------------VIISWLYITRVE--------DAINEYGHYMDGLLSSSAGERTAKNHGRVAKWFKCMPDID--
--------------------------------------------------------------------------------
-----
>Tetraodon_nigroviridis_TSPAN15a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------SNGDIRY
CHRFS---------------------------------YVFLKFLLFFYA---IVFWL---------------------I
GGFILAVGIYAEVERQ--------RYKTLEG----VFLAPAIIL---ILLGIVMF-VVSFIGVLASLRDNLILLKVF---
-MYTLTICLILELLGG--VLALLFHN----QTVELLNKNIRKGIVNYYDDLDFKNI-----------------MDFVQKK
--FKCCGG--------QEYKDWSVN------MYHNCS--APGP--------------LACGVPYTCCITNNP-----NA-
VANTFCGYKVL------------------GKERLDLIEVIYTRGCTD-AVFIWLTDNYKTMAGLLLG-ILLPQFFG----
------------------VIISWLYITRVE--------DAISEYGHYMDGLLDSGAGERAAKRHGRMAKWFKCMPDID--
--------------------------------------------------------------------------------
-----
>Tetraodon_nigroviridis_TSPAN15b
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------MP--SYTELRK
TNHFY----------------------------------YFIKFTLNVYS---MLFSL---------------------V
GLCVLCVGVYAEVERQ--------KNRTLEG----LFLAPAVVL---ILLGLVMF-TVSVVGMVGSLRDNKTLLHMF---
-LCVLCVLLLLQAVAL--TMALIFEK----KTSALFQSSIREGIKHYYDDLDFKNI-----------------LDYVQQK
--FSCCGG--------DEYKDWGVN------QYHFCN--GTGP--------------LACGVPYTCCVRHKV-----GE-
VINTLCGYQTL------------------DKARESLQDKIHVRGCIH-AVNLWMGDNIGITVALCCA-VGLPQLLG----
------------------IILSCVFWNLLV--------DMSESPDMVDFKLKKAEVNYSELDLAG--AGWCMCLPRDGGY
L-------------------------------------------------------------------------------
-----
>Gasterosteus_aculeatus_TSPAN15a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------MSDDDVRY
CERCS---------------------------------YIFLKLILFAYA---IIWWL---------------------I
GGFILAIGIYAEVERQ--------RYKTLEG----VFLAPAIIL---ILLGIIMF-IVSLVGLVGSLRDNLTLLKVF---
-MYTLAVCLILELLGG--ILALAFRH----QTVGLVNKNIRKGIVNYYDDLDFKNI-----------------MDFVQKR
--FKCCGG--------QEYTDWSVN------MYHNCS--ALSP--------------SACGVPYTCCITTKP-----NE-
VANTMCGYKVL------------------EKTRLELIEIIHIRGCTD-AFFIWLMDNYKIMAGLLLG-ILLPQFFG----
------------------VVVSWLYMTRVE--------DAISEYGHYMD-LLDSSADERVHKEQPHVAKWFRCMPEI---
--------------------------------------------------------------------------------
-----
>Oryzias_latipes_TSPAN15b
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------MP--PYSELRK
TNHFY----------------------------------FFIKFTLNIYS---MIFSL---------------------M
GLCVLCVGVYAEVERQ--------KNRTLEG----LFLAPAVLL---ILLGLVMF-TVSVVGMVGSLRDNKTLLHMF---
-LCVLCVLLLLQAVGL--VMALIFEK----KTSALFQRSLREGIKHYYDDLDFKNI-----------------LDYVQQK
--FSCCGG--------DEYKDWEVN------QYHFCN--GSGP--------------LACGVPYTCCVRGKV-----GE-
VINTLCGYNTL------------------SQQRETLQEVIHVRGCIH-AVNLWMSDNIGITVALCCA-IGLPQLLG----
------------------IILSCVFWNLLV--------DMSKSADMVDFKIKKAEFSYSELDLAG--AGWCLCLPRDGGY
LPVPASEPDLDPIDVHLQKLKKQQPRSYSQLQKLQQSRSASGLDEVDVGR------------------------------
-----
>Branchiostoma_floridae_TSPAN15
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------MTYLEQLVS------------------------------
-AAIMGLGIFAEVVRR--------DLGSMNT----FLVSPAAAL---IAAGLVVF-VVTFLGMAGALRDNLILLKIF---
-IGLMITGLLLQLIVG--LVAFAFKD----QAKNFINEQVSKGVKSYFADLDFKNT-----------------MDWVQER
--FYCCGG--------ADYEDWEKN------DYFRCA--SPGP--------------ASCGVPHTCCDRR----------
-------------------------------ARLELVDIVYIRGCTD-AVLIWFEDNFDIFAGLCIG-LLLPQLLG----
------------------ILLSYIYINRIE--------DEIDQIKTAPYGTWG-GGDDTDAPAEK---DTAV--------
--------------------------------------------------------------------------------
-----
>Homo_sapiens_TSPAN33
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------MARRPR-APAA
SGEEFS------------------------------FVSPLVKYLLFFFN----MLFWV--------------------I
SMVMVAVGVYARLMKH--------AEAALAC----LAVDPAILL---IVVGVLMF-LLTFCGCIGSLRENICLLQTF---
-SLCLTAVFLLQLAAG--ILGFVFSD----KARGKVSEIINNAIVHYRDDLDLQNL-----------------IDFGQKK
--FSCCGG--------ISYKDWSQN------MYFNCSEDNPSR--------------ERCSVPYSCCLPTPD-----QA-
VINTMCGQGMQ------------------AFDYLEASKVIYTNGCID-KLVNWIHSNLFLLGGVALG-LAIPQLVG----
------------------ILLSQILVNQIK--------DQIKLQLYNQQHRADPWY------------------------
--------------------------------------------------------------------------------
-----
>Mus_musculus_TSPAN33
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------MARRPG-VPAA
YGDEFS------------------------------FVSPLVKYLLFFFN----MLFWV--------------------I
SMVMVAVGVYARLMKH--------AEAALAC----LAVDPAILL---IVVGVLMF-LLTFCGCIGSLRENICLLQTF---
-SLCLTIVFLLQLAAG--ILGFVFSD----KARGKVSEIINNAIVHYRDDLDLQNL-----------------IDFGQKK
--FSCCGG--------ISYRDWSQN------MYFNCSEDNPSR--------------ERCSVPYSCCLPTPN-----QA-
VINTMCGQGMQ------------------ALDYLEASKVIYTNGCID-KLVNWIHSNLFLLGGVALG-LAIPQLVG----
------------------ILLSQVLVNQIK--------DQIKLQLYNQQHRADPWY------------------------
--------------------------------------------------------------------------------
-----
>Rattus_norvegicus_TSPAN33
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------MARRPG-VPAA
YGEEFS------------------------------FVSPLVKYLLFFFN----MLFWV--------------------I
SMVMVAVGVYARLMKH--------AEAALAC----LAVDPAILL---IVVGVLMF-LLTFCGCIGSLRENICLLQTF---
-SLCLTIVFLLQLAAG--ILGFVFSD----KARGKVSEIINNAIVHYRDDLDLQNL-----------------IDFGQKK
--FSCCGG--------ISYRDWSQN------MYFNCSEDNPSR--------------ERCSVPYSCCLPTPN-----QA-
VINTMCGQGMQ------------------ALDYLEASKVIYTNGCID-KLVNWIHSNLFLLGGVALG-LAIPQLVG----
------------------ILLSQVLVNQIK--------DQIKLQLYNQQHRADPWY------------------------
--------------------------------------------------------------------------------
-----
>Xenopus_tropicalis_TSPAN33
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------LAMARRSP--GSG
KEEDFS------------------------------FVSPVVKYLLFFFN----TLFWV--------------------I
SMVMVGIGVYARLLKH--------AEAAMAC----LAVDPALLL---IGVGILMF-LITFCGCIGSLRENICLLQTF---
-AICLTLVFLLQLAVG--IVGFIFSD----KARGKVSEIISNAIEHYRDDLDLQNL-----------------IDFGQKE
--FSCCGG--------ISYKDWSQN------MYFNCSSENRSR--------------ERCSVPYSCCLHDED-----EA-
VINTLCGQGMQ------------------ELDYLEAGAFIHTNGCID-RLVNWLHSNLFLLGGVALG-LAIPQLVG----
------------------ILLSQILINQIR--------DQIKLQRYNQQHKTDPWY------------------------
--------------------------------------------------------------------------------
-----
>Takifugu_rubripes_TSPAN33a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------MGGKRRGAPERT
YDEDFT------------------------------FVSPVVKYLLFIFN----FIFWV--------------------I
SMVMVSIGVYARMMKQ--------AETALAC----LSVDPAIML---LVVGVLMF-IITFCGCVGSLRENICLLQTF---
-CISLTVIFLLQLVAG--ILGFVFAD----KARDKVTKIINKAITYYRDDIDLQNL-----------------IDFGQTE
--FACCGG--------VAYTDWSSN------VYFNCSMQNPSR--------------ERCSVPFSCCVMTKITV-LEQM-
VINTMCGQGMQ------------------ILEYSEAATYIYTNGCID-KLVNLIHSNMFLLGGIAMG-LAIPQLVG----
------------------ILLSQILINQIK--------DQIELQRYNLKHRSDPWR------------------------
--------------------------------------------------------------------------------
-----
>Tetraodon_nigroviridis_TSPAN33a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------LFTHSVAMAERG
-DEDYT------------------------------YVSRVVKYLLFLFN----FIFWL--------------------I
SMVMVSIGVYARMIKH--------AETALAC----LTVDPAMML---LVVGILMF-IITFCGCVGSLRENICLLQTF---
-CICLTVIFLLQLIAG--ILGFIFAD----KARNKVTEIINNAITHYRDDIDLQNL-----------------IDFGQKE
--FSCCGG--------VAFTDWSNN------MYFNCSKQNPST--------------ERCSVPFSCCIVTNT-----QM-
VINTKCGQGMQ------------------LLEYTEAAASIHTNGCID-KLVNWIHSNMFLLGGIAMG-LAIPQLVG----
------------------IFLSQTLINQIK--------DQIALQSYTLRHRSDPWS------------------------
--------------------------------------------------------------------------------
-----
>Tetraodon_nigroviridis_TSPAN33b
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------MDRKLN---LD
RAETFS------------------------------FINPWIRYFLFFFS----FLFWI--------------------F
SLLIVAIGVYAKVQKVT--------DTVRDT----FFVDPAVIL---IVVGVIMF-FITFCGCIGALRENIRLLKMF---
-SFSLTLVFLTQLAMA--ILGFFYSD----QTRDALGKFVRKAIVHYRDDLDLQNL-----------------MDYVQKE
--FKCCGW--------NNYTDWSWN------LYFNCTPANPSS--------------ERCAVPYSCCTPIPG-----EA-
VINTMCGFGVQ------------------TQNHLEANRSIYAVGCAD-KAVMWMESHLLLVGALALG-LALPQIAG----
------------------IVLSQILISQIQ--------DEITLRLHRCEATARVCV------------------------
--------------------------------------------------------------------------------
-----
>Gasterosteus_aculeatus_TSPAN33a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------MGGRG-GAPGSG
--DDYS------------------------------FVSPVVKYLLFLFN----FIFWI--------------------C
SLVMVAIGVFARLMKH--------AEAALAC----LAVDPAVML---MVVGFLMF-IITFCGCVGSLRENICLLQTF---
-CICLTVIFLLQLIAG--ILGFVFAD----KSRDRVTWMINNAIVHYREDIDLQNL-----------------IDFGQRE
--FGCCGA--------VTYTDWSQN------MYFNCTQDNPSN--------------ERCSVPFSCCNLSED-----KV-
VINTMCGAGMQ------------------HLEYIEAGDHIYTNGCID-KLVNWIHSNMFLLGGVALG-LAIPQLVG----
------------------ILLSQILINQIK--------DQIALQNYNLKHRSDPWS------------------------
--------------------------------------------------------------------------------
-----
>Gasterosteus_aculeatus_TSPAN33b
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-AKDFS------------------------------FVNPWIRYFLFFFS----FVFWV--------------------F
SLLIVAVGVYAKIQKATGT----NIDAVRNT----FLIDPAVIL---IVVGVVMF-FITFCGCIGALRQNIRLLKTF---
-SLSLTLVFLTQLAIA--VLGFFYSE----QTRDALGKFVKKAVVHYRDDLDLQNL-----------------MDHIQKE
--FQCCGW--------NNYTDWSWN------LYFNCTHENPSS--------------ERCAVPYSCCAPVPG-----ET-
VINTMCGFGVQ------------------TMSHLEANKSIYAAGCMD-KAAMWIESHLLLVGALALG-TALPQIAG----
------------------IVLSHILVSQIQ--------GIQHNTEQQGDGAYLRITPAHF--------------------
--------------------------------------------------------------------------------
-----
>Oryzias_latipes_TSPAN33a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------ITMGNGKDAAT
SDAEFT------------------------------FVSPVVKYLLFVFN----FIFWV--------------------I
SFVMVGIGVYARLIKQ--------AETALAC----LTVDPAVML---MVVGIFMF-IVTFCGCVGSLRENICLLQTF---
-CISLTVIFILQLTAG--IMGFIFSD----KARGKVTEVINKSIIHYRDDVDLQNL-----------------IDYGQKE
--FRCCGG--------EAFTDWSQN------IYFNCSEKNPSR--------------ERCSVPFSCCIITKV-----KE-
LFNSMCGEGMQ------------------KLDYITAGQYVYTDGCID-KLVNWIHSNLFIIGGIALG-LAIPQLVG----
------------------ILLSQILINQIK--------DQIELQNYNARHRSDPWS------------------------
--------------------------------------------------------------------------------
-----
>Oryzias_latipes_TSPAN33b
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------TMERELS---LN
RAETFS------------------------------FVNPWIRYFLFFFS----FLFWV--------------------F
SLLIVAIGVYAKVQKAT--------ETVRDR----FLVDPAVIL---IVVGVVMF-FITFCGCIGALRENIRLLKTF---
-SFSLTLVFLIHLAVA--ILGFFYSD----QTRSALEKFARKAIVHYRDDLDLQNL-----------------MDYIQKE
--FKCCGW--------NSYTDWSWN------LYFNCTRENPSS--------------ERCAVPYSCCTPVPG-----ET-
VINTMCGFGVQ------------------TQKYLDANKSIYPVGCAD-RAVMWIETHLLLVGALTLG-LALPQVTK----
------------------THTSIEIIMGWP--------QGLRL-------------------------------------
--------------------------------------------------------------------------------
-----
>Homo_sapiens_CD151
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------MGEF-NEK
KTTCG---------------------------------TVCLKYLLFTYN---CCFWLA--------------------G
LA-VMAVGIWTLALKS-------DYISLLAS-------GTYLATAYILVVAGTVVMVTGVLGCCATFKERRNLLRL----
YFILLLIIFLLEIIAG--ILAYAYY---QQLNTELKENLKDTMTKR-YHQPGHEAV--------------TSAVDQLQQE
F--HCCG----------SNNSQDWR----D-SEWIR-----------------SQEAGGRVVPDSCCKTV----------
--VALCGQRDHASNIYKVEG-----------------------GCIT-KLETFIQEHLRVIGAVGIG---IACV---QVF
G-----------------MIFTCCLYRS-LKLE------HY---------------------------------------
--------------------------------------------------------------------------------
-----
>Macaca_mulatta_CD151
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------MGEF-NEK
KTTCG---------------------------------TVCLKYLLFTYN---CCFWLA--------------------G
LA-VMAVGIWTLALKS-------DYISLLAS-------GTYLATAYILVVAGAVVMVTGVLGCCATFKERRNLLRL----
YFILLLIIFLLEIIAG--VLAYVYY---QQLNTELKENLKDTMAKR-YHQPGHQAV--------------TSAVDQLQQE
F--HCCG----------SNNSQDWR----D-SEWIR-----------------SGEAGGRVVPDSCCKTV----------
--VAGCGQRDHASNIYKVEG-----------------------GCIT-KLETFIQEHLRVIGAVGTG---IACV---QVF
G-----------------MIFTCCLYRS-LKLE------HY---------------------------------------
--------------------------------------------------------------------------------
-----
>Mus_musculus_CD151
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------MGEF-NEK
KATCG---------------------------------TVCLKYLLFTYN---CCFWLA--------------------G
LA-VMAVGIWTLALKS-------DYISLLAS-------STYLATAYILVVAGVVVMVTGVLGCCATFKERRNLLRL----
YFILLLIIFLLEIIAG--ILAYVYY---QQLNTELKENLKDTMVKR-YHQSGHEGV--------------SSAVDKLQQE
F--HCCG----------SNNSQDWQ----D-SEWIR-----------------SGEADSRVVPDSCCKTM----------
--VAGCGKRDHASNIYKVEG-----------------------GCIT-KLETFIQEHLRVIGAVGIG---IACV---QVF
G-----------------MIFTCCLYRS-LKLE------HY---------------------------------------
--------------------------------------------------------------------------------
-----
>Rattus_norvegicus_CD151
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------MGEF-NEK
KATCG---------------------------------TVCLKYLLFTYN---CCFWLA--------------------G
LA-VMAVGIWTLALKS-------DYISLLAS-------STYLATAYILVVAGVVVMVTGVLGCCATFKERRNLLRL----
YFILLLIIFLLEIIAG--ILAYVYY---QQLNTELKENLKDTMIKR-YHQSGHEGV--------------TNAVDKLQQE
F--HCCG----------SNNSRDWR----D-SEWIR-----------------SGEADSRVVPDSCCKTV----------
--VTGCGKREHASNIYKVEG-----------------------GCIT-KLESFIQEHLRVIGAVGIG---IACV---QVF
G-----------------MIFTCCLYRS-LKLE------HY---------------------------------------
--------------------------------------------------------------------------------
-----
>Gallus_gallus_CD151
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------MREY-TEK
KETCG---------------------------------TICLKYLLFIFN---FFFWLA--------------------G
GA-VMAVGAWTLAKKS-------DYISLLSS-------STYSATAYILVVAGVVVMVTGILGCCATFKERRNLLRV----
YFILLLCIFLLEIIAG--ILAYIYY---QQLSTELKENLKNTMTEK-YRKEGEERV--------------TSAVDKLQQE
F--KCCG----------SNNYTDWA----D-SMWIK-----------------SPEASGRKVPDSCCKTI----------
--TVLCGRRDHPSNIYK-EN-----------------------GCIT-KLENFIQEHLKIIGIVGIS---IACV---QIF
G-----------------MIFTCCLYRS-LKQE------PY---------------------------------------
--------------------------------------------------------------------------------
-----
>Anolis_carolinensis_CD151
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------MREY-SEN
KETCG---------------------------------TICLKYLLFTFN---FFFWLA--------------------G
GA-VMAVGIWTLAEKS-------DYISLLQS-------NTYMATAYILVVAGVVVMITGILGCCATFREQRSLLRA----
YFILLLCIFLLEIIAG--ILAYIYY---QQLNAELKQNLKETMTKK-YQKEGEEGV--------------TSAVDKLQQE
F--KCCG----------SHNYTDWS----D-SDWIK-----------------SPEAKGRKVPDSCCKTI----------
--TTNCGTRDHPSNIYK-EG-----------------------GCIT-KLENFIQEHLKIIGAVGLG---IAFV---QIF
G-----------------MIFTCCLYRS-LKSE------PY---------------------------------------
--------------------------------------------------------------------------------
-----
>Takifugu_rubripes_CD151a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------MGAY-EEP
KETCG---------------------------------TICLKYLLFAFN---FMFWLA--------------------G
GV-VMAVGVWTLIEKT-------DYISLLPS-------MTYAASAYILVLAGVIVMVTGVLGCCATFKEHRKLLRV----
YFVLLLCIFLLEILAG--VLAYIYY---QQLNQELKQSLKETMTTK-YAQKGHDQV--------------TKAVDKLQQE
F--KCCG----------SNGSSDWA----E-SIFIR-----------------SG-ANGRLVPDSCCKTS----------
--TELCGLRDHPSNIYKVEG-----------------------GCIS-KLEEFILDHLKIIGAVGVG---IACV---QII
G-----------------MVFTCCLYRN-LKAE------PY---------------------------------------
--------------------------------------------------------------------------------
-----
>Tetraodon_nigroviridis_CD151a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------MGAY-EEP
KETCG---------------------------------TICLKYLLFAFN---FLFWLA--------------------G
GV-VMAVGVWTLIEKT-------DYISLLPS-------KTYAASAYILVLAGVIVMVTGVLGCCATFKEHRRLLRV----
YFVLLLCIFLLEILAG--VLAYIYY---QQLNEELKQSLKETMTKK-YSQSGYDQV--------------TQAVDKLQQG
F--KCCG----------SNGSSDWA----E-SLYIR-----------------SG-AEGRLVPDSCCKTP----------
--GQLCGLRDHPSNIYKVEG-----------------------GCIS-KLEQFTLDHLKIIGAVGVG---VACV---QIF
G-----------------MVFTCCLYRN-LKAE------PY---------------------------------------
--------------------------------------------------------------------------------
-----
>Gasterosteus_aculeatus_CD151a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------MGVY-EEK
KETCG---------------------------------TICLKYLLFSFN---FLFWLA--------------------G
GG-VMAVGVWTLVEKS-------DYISLLSS-------KTYAASAYILVLAGAIVMVTGVLGCCATFKEQRKLLRVVQ-G
YFVRLLCISLWEILSA--IRGYIYYQ--QQLNEELKQNLRETMTQK-YEQSSHEHV--------------TRAVDKLQQE
F--KCCG----------SNSSSDWS----D-SVWIR-----------------SRDAAGRMVPDSCCKTR----------
--TDLCGRRDHPSNIYKVEG-----------------------GCIT-KLENFILDHLKIIGAVGVG---IACV---QVI
G-----------------MVFTCCLYRS-LKAE------PY-