>Homo_sapiens_SLIT1
--------------------------------------------------------------------------------
-------------------------------------------------MALTPGWGSSAGPVRPELWLLL-WAAAWRLG
-ASACP-------------------------------------ALCTCTGTTVDCHGTGLQAIPKNIPRNTERLELN---
GNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIP
RKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFN-HMPKLRTFRLHSNHLFCDCHLAWLSQ
WLRQ-RPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSG---QGEAGRVPTCTLSSGSCPAMCTCSNGIVDCRGKGLTAIP
ANLPET-MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQG-LRSLNS-LVLYGNKITDLPRGVFGGLY
TLQLL-LLNANKINCIRPDAFQDLQN--LSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN---PFICDCNLKWLADFLR
TNP-IETSGARCASPRRLANKRIGQIKSKKFRCSAK-EQYFIPGTEDY--QLNSECNSDVVCPHKCRCEANVVECSSLKL
TKIP----ERIPQSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSG
MFRGLDGLRTL-MLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANPFNCNCQLAWLGGWL
RKR--KIVTGNPRCQNPDFLRQIP---LQDVAFPDFRCEE-------GQEEGGCLPRP-QCPQECACLDTVVRCSNKHLR
ALPKG-IPKNVTELYLDGN-QFTLVPGQL-STFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQG
LRSLR-LLSLHGNDISTLQEGIFADVTSLSHL----AIGANPLYCDCHLRWLSS-WVK--TGYKEPGIARCAG---PQDM
EGKLLLTTPAKKFECQG-------PPTLAVQAKCDLCLSSPCQNQGTCHND-PLEVYRCACPSGYKGRDCEVSLDSCSSG
PCENGGTCHAQEG-EDAPFTCSCPTGFEGPTCGVNTDDCVDHAC-ANGGVCVDGVGNYTCQ-------------------
---CPLQYEGK---------ACEQLVDLCSPDLNPCQHEAQCVGTPDGPR---------CECMPG---YAGDNCSENQDD
CRDHRCQNG--------AQCMDEVN---SYSCLCA-----EGYSGQLCEIPPHLPAPK---SPCEGTECQNGANCVDQ-G
NR---------PVCQCLPGFGGPECEKLLSVNF----VDRDTYLQFTDLQNWPRANITLQVSTAEDNG-ILLYNG-----
------------DNDHIAVELY----QGHVRVSYDPGSYPSSAIYS-------AETINDGQFHTVELVAFDQMVN-LSID
GG------SPMTMDNFGKHYTLNSEAP--------------------------------LYVG----------GMPVDVN
SAAFR-----LWQILNGTGFHGCIRNLY-------------------INNELQDFTK-----------------TQMKPG
VVPGCEP-----------CRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPA---------------DGPCHGHKCVH
GQ-CVPLD------------------------------ALSYSCQCQDGYSGALCNQAGA--------------------
-----------LAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGEL-CEQ--ESE---------CRGDPVRDFHQVQRGY
AICQTTRPLSWVECRGSCP---------------------------GQGCCQGLRLKRRKFTFECSDGTSFAEEVEKPTK
CGCALCA-------------------------------------------------------------------------
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---------------------
>Gorilla_gorilla_SLIT1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------MLPELLFQNNQALSRLDLSENAIQAIP
RKAFRGATDLKNLQLDKNRISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFN-HMPKLRTFRLHSNHLFCDCHLAWLSQ
WLRQ-RPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSG---QGEAGRVPTCTLSSGSCPAMCTCSNGIVDCRGKGLTAIP
ANLPET-MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQG-LRSLNS-LVLYGNKITDLPRGVFGGLY
TLQLL-LLNANKINCIRPDAFQDLQN--LSLLSLYDNKIQSLAKGTFTSLRAIQTLSLFQT---PNSCKATLNFHAHLLD
VNN-IDFA-AVLLAPRDLTFKRPGAVAHTCFRCSAK-EQYFIPGTEDY--QLNSECSSDVVCPHKCRCEANVVECSSLKL
TKIP----ERIPQSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSG
MFRGLDGLRTL-MLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANPFNCNCQLAWLGGWL
RKR--KIVTGNPRCQNPDFLRQIP---LQDVAFPDFRCEE-------GQEEGSCLPRP-QCPQECACLDTVVRCSNKHLR
ALPKG-IPKNVTELYLDGN-QFTLVPGQL-STFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALRCIPPLAFQG
LRSLR-LLSLHGNDISTLQEGIFADVTSLSHL----AIGANPLYCDCHLRWLSS-WVK--TGYKEPGIARCAG---PQDM
EGKLLLTTPAKKFECQG-------PPTLAVQAKCDPCLSSPCQNQGTCHND-PLEE---------QGRDCEVSLDSCSSG
PCENGGTCHAQEG-EDVPFTCSCPTGFEGPTCGVNTDDCVDHAC-ANGGICVDGVGNYTCQ-------------------
---CPLQYEGK---------ACEQLVDLCSPDLNPCQHEAQCVSTPDGPR---------CECMPG---YAGDNCSENQDD
CRDHRCQNG--------AQCMDEVN---SYSCLCA-----EGYSGQLCEIPPHLPAPK---SPCEGTECQNGANCVDQ-G
NR---------PVCQCLPGFGGPECEKLLSVNF----VDRDTYLQFTDLQNWPRANITLQVSTAEDNG-ILLYNG-----
------------DNDHIAVELY----QGHVRVSYDPGSYPSSAIYS-------AETINDGQFHTVELVAFDQMVN-LSID
GG------SPMTMDNFGKHYTLNSEAP--------------------------------LYVG----------GMPVDVN
SAAFR-----LWQILNGTGFHGCIRNLY-------------------INNELQDFTK-----------------TQMKPG
VVPGCEP-----------CRKLYCLHGICQPNATPGPMCHCESGWVGLHCDQPA---------------DGPCHGHKCVH
GQ-CVPLD------------------------------ALSYSCQCQDGYSGALCNQAGA--------------------
-----------LAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGEL-CEQ--ESE---------CRGDPVRDFHQVQRGY
AICQTTRPLSWVECQGSCP---------------------------GQGCCQGLRLKRRKFTFECSDGTSFAEEVEKPTK
CGCALCA-------------------------------------------------------------------------
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---------------------
>Pongo_abelii_SLIT1
-----MTAGWERARGCVCVWCVRRVRARAGPAHFPPRSSQLGAGGRERETQAAKRRGAERPPPKAPSLRPRTGAVAWRSK
VPPSPQGRRAQARGLFGGSAPGLHLEAAPDGDGQRLLPSGSRAGRGEGTMALTPGWGSSAGPVRPELWLLL-WAAAWRLG
-ASACP-------------------------------------ALCTCTGTTVDCHGTGLQAIPKNIPRNTERLELN---
GNNITRIHKNDFVGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIP
RKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFN-HMPKLRT-------------------
-----------------------------------------QGEAGRVPTCTLSSGSCPAMCTCSNGIVDCRGKGLTAIP
ANLPET-MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQG-LRSLNS-LVLYGNKITDLPRGVFGGLY
TLQLL-LLNANKINCIRPDAFQDLQN--LSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN---PFICDCNLKWLADFLR
TNP-IETSGARCASPRRLANKRIGQIKSKKFRCSAK-EQYFIPGTEDY--QLNSECNSDVVCPHKCRCEASVVECSSLKL
TKIP----ERIPQSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAGSVSELHLTANQLESIRSG
MFRGLDGLRTL-MLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANPFNCNCQLAWLGGWL
RKR--KIVTGNPRCQNPDFLRQIP---LQDVAFPDFRCEE-------GQEEGGCLPRP-QCPQECACLDTVVRCSNKHLR
ALPKG-IPKNVTELYLDGN-QFTLVPGQL-STFKYLQLV------------------------ILSYNALQCIPPLAFQG
LRSLR-LLSLHGNDISTLQEGIFADVTSLSHL----AIGANPLYCDCHLRWLSS-WVK--TGYKEPGIARCAG---PQDM
EGKLLLTTPAKKFECQG-------PPTLAVQAKCDPCLSSPCQNQGTCHND-PLEVYRCACPSSYKGRDCEVSLDSCSSG
PCENGGTCHAQEG-EDAPFTCSCPTGFEGPTCGVNMDDCVDHAC-ANGGVCVDGVGNYTCQ-------------------
---CPLQYEGK---------ACEQLVDLCSPDLNPCQHEAQCVGTPDGPR---------CECMPG---YAGDNCSENQDD
CRDHRCQNG--------AQCIDEVN---SYSCLCA-----EGYSGQLCEIPPHLPAPK---SPCEGTECQNGANCVDQ-G
NR---------PVCQCLPGFGGPECEKLLSVNF----VDRDTYLQFTDLQNWPRANITLQVSTAEDNG-ILLYNG-----
------------DNDHIAVELY----QGHVRVSYDPGSYPSSAIYS-------AETINDGQFHTVELVAFDQMMN-LSID
GG------SPMTMDNFGKHYTLNSEAP--------------------------------LYVG----------GMPVDVN
SAAFR-----LWQILNGTGFHGCIRNLY-------------------INNELQDFTK-----------------TQMKPG
VVPGCEP-----------CRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPA---------------DGPCHGHKCVH
GQ-CVPLD------------------------------ALSYSCQCQDGYSGALCNQAGA--------------------
-----------LAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGEL-CEQ--ESE---------CRGDPVRDFHQVQRGY
AICQTTRPLSWVECRGSCP---------------------------GQGCCQGLRLKRRKFTFECSDGTSFAEEVEKPTK
CGCALCA-------------------------------------------------------------------------
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---------------------
>Macaca_mulatta_SLIT1
--------------------------------------------------------------------------------
-------------------------------------------------MALTPGWGSSAGPVRPELWLLL-WAAAWSLG
-ASACP-------------------------------------ALCTCTGTTVDCHGTGLQAIPKNIPRNTERLELN---
GNNITRIHKNDFVGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIP
RKAFRGATDLKNLQLDKNQINCIEEGAFRALRGLEVLTLNNNNITTIPVSSFN-HMPKLRTFRLHSNHLFCDCHLAWLSQ
WLRQ-RPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSG---QGEAGRVPTCTLSSGSCPAMCTCSNGIVDCRGKGLTAIP
ANLPET-MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQG-LRSLNS-LVLYGNKITDLPRGVFGGLY
TLQLL-LLNANKINCIRPDAFQDLQN--LSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN---PFICDCNLKWLADFLR
TNP-IETSGARCASPRRLSNKRIGQIKSKKFRCSAK-EQYFIPGTEDY--QLNSECNSDVICPHKCRCEASVVECSSLKL
TKIP----ERIPQSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSG
MFRGLDGLRTL-MLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANPFNCNCQLAWLGGWL
RKR--KIVTGNPRCQNPDFLRQIP---LQDVAFPDFRCEE-------GQEEGGCLPRP-QCPQECACLDTVVRCSNKHLR
ALPKG-IPKNVTELYLDGN-QFTLVPGQL-STFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQG
LRSLR-LLSLHGNDISTLQEGIFADVTSLSHL----AIGANPLYCDCHLRWLSS-WVK--TGYKEPGIARCAG---PLDM
EGKLLLTTPAKKFECQG-------PPTLAVQAKCDPCLSSPCQNQGICHND-PLEVYRCACPSGYKGRDCEVSLDSCSSG
PCENGGTCHAQEG-KDAPFMCSCPTGFEGPTCGVNTDDCVDHAC-ANGGVCVDGVGNYTCQ-------------------
---CPVQYEGR---------ACEQLVDLCSPDLNPCQHEARCVGTPDGPR---------CECVPG---YAGDNCSENQDD
CRDHRCQNG--------AQCMDEVN---SYSCLCA-----EGYSGQLCEIPPHLPTPK---SPCEGTECQNGANCVDQ-G
NR---------PVCQCLPGFGGPECEKLLSVNF----VDRDTYLQFTDLQNWPRANITLQVIVSQNQGRDLVSWG-----
------------EPAGVSGEVPR---QGWSRLTPTPG-WGTPSCSS-------AETINDGQFHTVELVAFDQMVN-LSID
GG------SPMTMDNFGKHYTLNSEAP--------------------------------LYVG----------GMPVDVN
SAAFR-----LWQILNGTGFHGCIRNLY-------------------INNELQDFTK-----------------TQMKPG
VVPGCEP-----------CLKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPA---------------DGPCHGHKCVH
GQ-CVPLD------------------------------ALSYSCQCQDGYSGALCNQAGA--------------------
-----------LAEPCRGLQCLHGHCQASATKGAHCVCDPGFSGEL-CEQ--ESE---------CRGDPVRDFHQVQRGY
AICQTTRPLSWVECRGSCP---------------------------GQGCCQGLRLKRRKFTFECSDGTSFAEEVEKPTK
CGCALCA-------------------------------------------------------------------------
--------------------------------------------------------------------------------
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---------------------
>Callithrix_jacchus_SLIT1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------MLPELLFQNNQALSRLDLSENAIQAIP
RKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFN-HMPKLRTFRLHSNHLFCDCHLAWLSQ
WLRQ-RPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSG---PGEAGRVPTCTLSSGSCPAMCTCSNGIVDCRGKGLTAIP
ANLPET-MTEIRLELNSIKSIPPGAFSRYRKLRRIDLSNNQIAEIAPDAFQG-LRSLNS-LVLYGNKITDLPRGVFGGLY
TLQLL-LLNANKINCIRPDAFQDLQN--LSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN---PFICDCNLKWLADFLR
TNP-IETSGARCASPRRLANKRIGQIKSKKFRCSAK-EQYFIPGTEDY--QLNHEFVYTYVYAHRC-LQASVIYICKFFM
AFLM----DLKCPSFVDVRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSG
MFRGLDGLRTL-MLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANPFNCNCQLAWLGDWL
RKR--KIVTGNPRCQNPDFLRQIP---LQDVAFPDFRCEE-------GQEEGGCLPRP-QCPQECACLDTVVRCSNKHLR
ALPRG-VPKNVTELYLDGN-QFTLVPGQL-FTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQG
LRSLR-LLSLHGNDISTLREGIFADVTSLSHL----AIGANPLYCDCHLRWLSS-WVK--TGYKEPGIARCAG---PPDM
EGKLLLTTPAKKFECQG-------KPRIGVGEKGFLCFSVAAGSSGYLHSQCILEMLEGSAIAGRQGRDCEVSLDSCSSG
PCENGGTCHAQED-EDAPFTCSCPTGFEGPTCGVNTDDCVEHAC-ANGGICVDGVGNYTCQ-------------------
---CPLQYEGR---------ACEQLVDLCSPDLNPCQHKAQCVGTPDGPR---------CECVPG---YAGDNCSENQDD
CRDHRCQNG--------AQCVDEVN---SYSCLCA-----EGYSGQLCEIPPHPPAPK---SPCEGTECQNGANCVDQ-G
NR---------PVCQCLPGFGGPECEKLLSVNF----VDRDTYLQFTDLQNWPRANITLQVSTAEDNG-ILLYNG-----
------------DNDHIAVELY----QGHVRVSYDPGSYPSSAIYS-------AETINDGQFHTVELVAFDQMVN-LSID
GG------SPMTMDNFGKHYTLNSEAP--------------------------------LYVG----------GMPVDIN
SAAFR-----LWQILNGTSFHGCIRNLY-------------------INNELQDFTK-----------------TQMKPG
VVPGCEP-----------CRKLYCLHGICQPNATPGPTCHCEAGWGGLHCDQPT---------------DGPCHGHKCVH
GQ-CVPLD------------------------------ALSYSCQCQDGYSGALCNQAGA--------------------
-----------PAEPCRGLQCLHGHCQASANKGAHCVCDPGFSGEL-CEQ--ESE---------CRGDPVRDFHQVQRGY
AVCRTTRPLSWVECQGSCP---------------------------GQGCCQGLRLKRRKFTFECSDGTSFAEEVEKPTK
CGCALCA-------------------------------------------------------------------------
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---------------------
>Mus_musculus_SLIT1
--------------------------------------------------------------------------------
-------------------------------------------------MALTPQRGSSSGLSRPELWLLL-WAAAWRLG
-ATACP-------------------------------------ALCTCTGTTVDCHGTGLQAIPKNIPRNTERLELN---
GNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLQVLPELLFQNNQALSRLDLSENFLQAVP
RKAFRGATDLKNLQLDKNRISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFN-HMPKLRTFRLHSNHLFCDCHLAWLSQ
WLRQ-RPTIGLFTQCSGPASLRGLNVAEVQKGEFSCSG---QGEAAGAPACTLSSGSCPAMCSCSSGIVDCRGKGLTAIP
ANLPET-MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQG-LRSLNS-LVLYGNKITDLPRGVFGGLY
TLQLL-LLNANKINCIRPDAFQDLQN--LSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN---PFICDCNLKWLADFLR
TNP-IETTGARCASPRRLANKRIGQIKSKKFRCSAK-EQYFIPGTEDY--HLNSECTSDVACPHKCRCEASVVECSSLKL
SKIP----ERIPQSTTELRLNNNEISILEATGLFKKLSHLKKINLSNNKVSEIEDGTFEGAASVSELHLTANQLESIRSG
MFRGLDGLRTL-MLRNNRISCIHNDSFTGLRNVRLLSLYDNHITTISPGAFDTLQALSTLNLLANPFNCNCHLSWLGDWL
RKR--KIVTGNPRCQNPDFLRQIP---LQDVAFPDFRCEE-------GQEEVGCLPRP-QCPQECACLDTVVRCSNKHLQ
ALPKG-IPKNVTELYLDGN-QFTLVPGQL-STFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQG
LRSLR-LLSLHGNDVSTLQEGIFADVTSLSHL----AIGANPLYCDCRLRWLSS-WVK--TGYKEPGIARCAG---PPEM
EGKLLLTTPAKKFECQG-------PPSLAVQAKCDPCLSSPCQNQGTCHND-PLEVYRCTCPSGYKGRHCEVSLDGCSSN
PCGNGGTCHAQEG-EDAGFTCSCPSGFEGPTCGVDTDDCVKHAC-VNGGVCVDGVGNYTCQ-------------------
---CPLQYTGR---------ACEQLVDFCSPDMNPCQHEAQCVGTPDGPR---------CECMLG---YTGDNCSENQDD
CKDHKCQNG--------AQCVDEVN---SYACLCV-----EGYSGQLCEIP---PAPR---SSCEGTECQNGANCVDQ-G
SR---------PVCQCLPGFGGPECEKLLSVNF----VDRDTYLQFTDLQNWPRANITLQVSTAEDNG-ILLYNG-----
------------DNDHIAVELY----QGHVRVSYDPGSYPSSAIYS-------AETINDGQFHTVELVTFDQMVN-LSID
GG------SPMTMDNFGKHYTLNSEAP--------------------------------LYVG----------GMPVDVN
SAAFR-----LWQILNGTSFHGCIRNLY-------------------INNELQDFTK-----------------TQMKPG
VVPGCEP-----------CRKLYCLHGICQPNATPGPVCHCEAGWGGLHCDQPV---------------DGPCHGHKCVH
GK-CVPLD------------------------------ALAYSCQCQDGYSGALCNQVGA--------------------
-----------VAEPCGGLQCLHGHCQASATKGAHCVCSPGFSGEL-CEQ--ESE---------CRGDPVRDFHRVQRGY
AICQTTRPLSWVECRGACP---------------------------GQGCCQGLRLKRRKLTFECSDGTSFAEEVEKPTK
CGCAQCA-------------------------------------------------------------------------
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---------------------
>Rattus_norvegicus_SLIT1
--------------------------------------------------------------------------------
-------------------------------------------------MALTPQRGSSSGLSRPELWLLL-WAAAWRLG
-ATACP-------------------------------------ALCTCTGTTVDCHGTGLQAIPKNIPRNTERLELN---
GNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLQVLPELLFQNNQALSRLDLSENSLQAVP
RKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFN-HMPKLRTFRLHSNHLFCDCHLAWLSQ
WLRQ-RPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSG---QGEAAQVPACTLSSGSCPAMCSCSNGIVDCRGKGLTAIP
ANLPET-MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQG-LRSLNS-LVLYGNKITDLPRGVFGGLY
TLQLL-LLNANKINCIRPDAFQDLQN--LSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN---PFICDCNLKWLADFLR
TNP-IETTGARCASPRRLANKRIGQIKSKKFRCSAK-EQYFIPGTEDY--HLNSECTSDVACPHKCRCEASVVECSGLKL
SKIP----ERIPQSTTELRLNNNEISILEATGLFKKLSHLKKINLSNNKVSEIEDGTFEGATSVSELHLTANQLESVRSG
MFRGLDGLRTL-MLRNNRISCIHNDSFTGLRNVRLLSLYDNHITTISPGAFDTLQALSTLNLLANPFNCNCQLAWLGDWL
RKR--KIVTGNPRCQNPDFLRQIP---LQDVAFPDFRCEE-------GQEEVGCLPRP-QCPQECACLDTVVRCSNKHLQ
ALPKG-IPKNVTELYLDGN-QFTLVPGQL-STFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQG
LRSLR-LLSLHGNDVSTLQEGIFADVTSLSHL----AIGANPLY-DCHLRWLSS-WVK--TGYKEPGIARCAG---PPEM
EGKLLLTTPAKKFECQG-------PPSLAVQAKCDPCLSSPCQNQGTCHND-PLEVYRCTCPSGYKGRNCEVSLDSCSSN
PCGNGGTCHAQEG-EDAGFTCSCPSGFEGLTCGMNTDDCVKHDC-VNGGVCVDGIGNYTCQ-------------------
---CPLQYTGR---------ACEQLVDFCSPDLNPCQHEAQCVGTPEGPR---------CECVPG---YTGDNCSKNQDD
CKDHQCQNG--------AQCVDEIN---SYACLCA-----EGYSGQLCEIP---PAPR---NSCEGTECQNGANCVDQ-G
SR---------PVCQCLPGFGGPECEKLLSVNF----VDRDTYLQFTDLQNWPRANITLQVSTAEDNG-ILLYNG-----
------------DNDHIAVELY----QGHVRVSYDPGSYPSSAIYS-------AETINDGQFHTVELVTFDQMVN-LSID
GG------SPMTMDNFGKHYTLNSEAP--------------------------------LYVG----------GMPVDVN
SAAFR-----LWQILNGTSFHGCIRNLY-------------------INNELQDFTK-----------------TQMKPG
VVPGCEP-----------CRKLYCLHGICQPNATPGPVCHCEAGWGGLHCDQPV---------------DGPCHGHKCVH
GK-CVPLD------------------------------ALAYSCQCQDGYSGALCNQVGA--------------------
-----------VAEPCGGLQCLHGHCQASATRGAHCVCSPGFSGEL-CEQ--ESE---------CRGDPVRDFHRVQRGY
AICQTTRPLSWVECRGACP---------------------------GQGCCQGLRLKRRKLTFECSDGTSFAEEVEKPTK
CGCAPCA-------------------------------------------------------------------------
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---------------------
>Oryctolagus_cuniculus_SLIT1
MRTSSTCLQRKFAGVGNPAVRGPSPGNSWIPWFPPGESSQLGAAGRERETQAARNPSGAERPPPKAPSPGPRTSAVAGSR
KVPPSPQGRSAGLAGCGVALPRTAPGGGPARGWSAAAAVWHASGRGEGTMALTAQRGS-----RPELWLLLLWAAACLPG
-ASACP-------------------------------------ALCTCSGTTVDCHGTGLQAVPKNIPRSTERLELN---
GNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHTLPELLFQNNQALSRLDLSENAIQSIP
RKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFN-HMPKLRTFRLHSNHLFCDCHLAWLSQ
WLRQ-RPTIGLFTQCAGPASLRGLNVAEVQKNEFSCSG---QGEAGRVPTCTLSSGSCPAMCTCSNGIVDCRGKGLTAIP
ANLPET-MTEIRLELNGIQSIPPGAFSPYRKLRRIDLSNNHISEIAPDAFQG-LRSLNS-LVLYGNKITDLPRGVFSGLY
TLQLL-LLNANKINCIRPDAFQDLQN--LSLLSLYDNKIQSLARGTFTSLRAIQTLHLAQN---PFICDCSLKWLADFLR
TNP-IETSGARCASPRRLANKRIGQIKSKKFRCSAK-EQYFIPGTEDY--QLNSECNSDVVCPHKCRCEASVVECSSLKL
TKIP----ERIPQSTAELRLNNNEIAILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSG
MFRGLDGLRTL-MLRNNRISCIHNDSFTGLRNVRLLSLYDNHITTIAPGAFDTLQALSTLNLLANPFNCDCQLAWLGDWL
RKR--RVVTGNPRCQNPDFLRQIP---LQDVAFPDFRCEE-------GQEEGGCLPRP-QCPQECACLDTVVRCSNKHLR
ALPVG-IPKNVTELYLDGN-QFTQVPGQL-STFKFLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQG
LRSLR-LLSLHGNDVATLQEGTFTDVTSLSHL----AIGANPLYCDCHLRWLSS-WVK--TGYKEPGIARCAG---PPHM
EGKLLLTTPAKKFECQG-------PPTLAVQAKCDPCLSSPCQNQGTCHND-VLERYRCTCASGYKGRDCEVSSDSCFSS
PCGNGGTCQAQEG-EDAGFTVSCALG----RCGVGSEDDVDSTG-RGGQSCLSVPPNYLMQKTLLLS-------------
---CPLKWEAAP--------VTPSLKPLCCQSPKPWQETVNFR---TGPA---------CECAPG---YAGDNCSENQDD
CRDHRCQNG--------AQCVDEVN---SYTCVCA-----EGYSGQLCEIPSQPPAPR---SPCEGTECQNGANCVDQ-G
SR---------PVCQCLPGFGGPECEKLLSVNF----VDRDTYLQFTDLQNWPRANITLQVSTAEDNG-ILLYNG-----
------------DNDHIAVELY----QGHVRVSYDPGSYPSSAIYS-------TETINDGQFHTVELVTFDQMVN-LSID
GG------SPMTMDNFGKHYTLNSEAP--------------------------------LYVG----------GMPVDVN
SAAFR-----LWQILNGTSFHGCIRNLY-------------------INNELQDFTK-----------------TQMKPG
VVPGCEP-----------CRKLYCLHGICQPDATPGPVCHCDAGWGGVHCDQPA---------------DGPCLGHKCVH
GK-CVPLD------------------------------ALSYSCQCQEGYSGALCNQAGA--------------------
-----------PAEPCGGLQCLHGHCQASAAKGAHCVCDPGFSGEL-CEQ--ESE---------CRGDPVRDFHQVQRGY
AICQTTRPLSWVECRGSCP---------------------------GSGCCRGLRLKRRKLTFECSDGTSFAEEVEKPTK
CGCALCA-------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------
>Canis_familiaris_SLIT1
--------------------------------------------------------------------------------
-------------------------------------------------MALAPRRGPPARRVRPELWLLL-WAAAWRLG
-ATACP-------------------------------------ALCTCTGATVDCHGAGLQAIPKNIPRSTERLELN---
GNNITRIHKNDFVGLKQLRVLQLMENQIGVVERGAFDDMKELERLRLNRNQLHTLPELLFQNNQALSRLDLSENTIQAIP
RKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFN-HMPKLRTFRLHSNHLFCDCHLAWLSQ
WLRQ-RPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSG---QGEAGRVPSCTLSSGSCPAMCSCSNGIVDCRGKGLTAIP
ANLPET-MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQG-LRSLNS-LVLYGNKITDLPRGVFGGLY
TLQLL-LLNANKINCVRPDAFQDLQN--LSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN---PFICDCNLKWLADFLR
TNP-IETSGARCASPRRLANKRIGQIKSKKFRCSAK-EQYFIPGTEDY--QLNSECNSDAVCPHKCRCEASLAECSSLKL
TKIP----ERIPQSTAELRLNNNEISILEATGIFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSG
MFRGLDGLRTL-MLRNNRISCIHNDSFTGLRNVRLLSLYDNQIATISPGAFDTLQALSTLNLLANPFNCNCQLAWLGDWL
RRR--KIVTGNPRCQNPDFLRQIP---LQDVAFPDFRCEE-------GQEEGSCLPRP-QCPQECACLDTVVRCSNKHLH
VLPKG-IPKNVTELYLDGN-QFTLVPGQL-STFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQG
LRSLR-LLSLHGNDISTLREGIFTDVTSLSHL----AIGANPLYCDCHLRWLSS-WVK--TGYKEPGIARCVG---PPDM
EGKLLLTTPAKKFECQG-------PPTLAVQAKCDPCLSSPCRNQGTCHND-PLEVYRCVCSSGYKGRDCEVSLDGCSSS
PCGNGGTCRPQEG-GDAGFTCSCPPGFEGPTCEVNTDDCVEHTC-ANGGICVDGVGNYTCQ-------------------
---CPLQYTGR---------GCEQLVDFCSSDLNPCQHEAQCVGTPDGPR---------CECAPG---YVGDNCSENQDD
CRDHRCQHG--------AQCVDEVN---SYSCLCA-----EGYSGQFCEAPPRPPAPR---SPCEGTECQNGANCVDQ-G
SG---------PVCQCLPGFGGPECEKLLSVNF----VDRDTYLQFTDLQNWPRANITLQVSTAEDNG-ILLYNG-----
------------DNDHMAVELY----QGHVRVSYDPGSYPSSAIYS-------AETINDGQFHTVELVTFDQMVN-LSID
GG------SPMTMDNFGKHYTLNSEAP--------------------------------LYVG----------GMPVDVN
SAAFR-----LWQILNGTSFHGCIRNLY-------------------INNELQDFTK-----------------TRMKPG
VVPGCEP-----------CRKLYCLHGICQPNATPGPVCHCEAGWGGLHCDQPA---------------DGPCHGHKCVH
GK-CVPLD------------------------------ALSYSCQCQDGYSGALCNQARA--------------------
-----------PADPCGGLQCLHGHCQVLATKGAHCVCDPGFSGEL-CEQ--ESE---------CRGDPVRDFHQVQRGY
AICQTTRPLSWVECRGSCP---------------------------GQGCCQGLRLKRRKLTFECSDGTSFAEEVEKPTK
CGCAVCA-------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------
>Felis_catus_SLIT1
--------------------------------------------------------------------------------
-------------------------------------------------MALTPGRGPSAGLVRPELWLLL-WAAAWRLG
-ATACP-------------------------------------ALCTCTGTTVDCHGTGLQAIPKNIPRNTERLELN---
GNNITRIHKNDFVGLKQLRVLQLMENQIGVVERGAFDDMKELERLRLNRNQVHSLPELLFQNNQALSRLDLSENTIQAIP
RKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFN-HMPKLRTFRLHSNHLFCDCHLAWLSQ
WLRQ-RPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSG---QGEAGRVPSCTLSSGSCPAMCTCSNGIVDCRGKGLTAIP
ANLPES-MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQG-LRSLNS-LVLYGNKITDLPRGVFGGLY
TLQLL-LLNANKINCVRPDAFQDLQN--LSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN---PFICDCNLKGLADFLR
TNP-IETSGARCASPRRLANKRIGQIKSKKFRCSAK-EQYFIPGTEDY--QLNSECNSDVVCPHKCRCEASLVECSSLKL
TKIP----ERIPQSTAELRLNNNEISILEATGIFKKLTHLKKINLSNNKVSEIEDGAFEGAGSVSELHLTANQLESIRSG
MFRGLDGLRTL-MLRNNRISCIHNDSFTGLRNVRLLSLYDNQIATISPGAFDTLQALSTLNLLANPFNCNCQLAWLGDWL
RRR--KIVTGNPRCQNPDFLRQIP---LQDVAFPDFRCEE-------GQEEGGCLPRP-QCPQECACLDTVVRCSNKHLQ
VLPKG-IPKNVTELYLDGN-QFTLVPGQL-STFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQG
LRSLR-LLSLHGNDISTLQEGIFTDVTSLSHL----AIGANPLYCDCHLRWLSG-WVK--TGYKEPGIARCAG---PPDM
EGKLLLTTPAKKFECQG-------PPALAVQAKCDPCLSSPCQNQGTCHND-ALEAYRCVCSSSYKGRDCEVSLDSCSSS
PCGNGGTCHPRQG-EDAGFMCSCPTGFEGPTCEVNTDDCVEHTC-ANGGTCVDGVGNYTCQ-------------------
---CPLQYAGR---------ACEQLVDFCSPDLNPCQHGAQCVGTPDGPR---------CECASG---YAGNNCSENQDD
CRDHRCQHG--------ARCVDGVN---SYSCLCA-----EGYSGQFCETPPRPPAPR---SPCEGTECQNGANCVDQ-G
SG---------PVCQCLPGFGGPECEKLLSVNF----VDRDTYLQFTDLQNWPRANITLQVSTAEDNG-ILLYNG-----
------------DNDHIAVELY----QGHVRVSYDPGSYPSSAIYS-------AETINDGQFHTVELVTFDQMVN-LSID
GG------SPMTMDNFGKHYTLNSEAP--------------------------------LYVG----------GMPVDVN
SAAFR-----LWQILNGTSFHGCIRNLY-------------------INNELQDFTK-----------------TRMKPG
VVPGCEP-----------CRKLYCLHGICQPNATPGPVCHCEAGWGGLHCDQPA---------------DGPCHGHKCVH
GQ-CMPLD------------------------------ALSYSCQCQDGYSGALCNQAGA--------------------
-----------PVDPCGGLQCLHGHCQALATKGAHCVCDPGFSGEL-CEQ--ESE---------CRGDPVRDFHQVQRGY
AICQTTRPLSWVECRGSCP---------------------------GQGCCQGLRLKRRKFTFECSDGTSFAEEVEKPTK
CGCALC--------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------
>Bos_taurus_SLIT1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------DLSENTIQAIP
RKAFRGATDLKNLQLDKNQIGCIEEGAFRALRGLEVLTLNNNNITTIPVSSFN-HMPKLRTFRLHSNHLFCDCHLAWLSQ
WLRQ-RPTIGLFTQCSGPAGLRGLNVAEVQKSEFSCSG---QGEAGRTPSCTLSSGSCPAMCACSNGIVDCRGKGLTAIP
ANLPEA-MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQISEIAPDAFQG-LRSLNS-LVLYGNKITDLPQGVFGGLF
TLQLL-LLNANKINCIRLDAFQDLQN--LSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN---PFICDCNLKWLADFLR
SNP-IETSGARCASPRRLANKRIGQIKSKKFRCSAK-EQYFIPGAEDY--QLNSECNSDVVCPHKCRCEASMVECSSLKL
TKIP----ERVPQATAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSG
MFRGLEGLRTL-MLRNNRISCIHNDSFTGLRNVRLLSLYDNQIATISPGAFDTLQALSTLNLLANPFNCNCQLAWLGDWL
RKR--KIVTGNPRCQNPDFLRQIP---LQDVASPDFRCEE-------GQEEGGCLPRP-QCPQECACLDTVVRCSNKHLQ
TLPKG-IPKNVTELYLDGN-QFTLVPAQL-STFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNSLQCIPPLAFQG
LRSLR-LLSLHGNDISTLQEGIFADVTSLSHL----AIGANPLYCDCHLRWLSS-WVK--TGYKEPGIARCAG---PLDM
EGKLLLTTPAKKFECQG-------PPTLTVQAKCDPCLSSPCQNQGTCRND-PLVGYRCACPSGYKGRDCEVSLDSCSSS
PCGNGGTCRSQEG-EDAGFTCSCPTGFEGPTCGVDTDDCVEHSC-ANGGTCVDGVGSYTCQ-------------------
---CPLQYSGR---------ACELLVDFCAPDLNPCQHEAQCVGTPDGPR---------CECAPG---YAGGNCTEKQDD
CRDHRCQNG--------AQCVDEAN---GYSCLCT-----QGYSGQLCETPPRPPGPR---SPCEGTECQNGANCVDQ-G
NG---------PVCQCLPGFGGPECEKLLSVNF----VDRDTYLQFTDLQNWPRANITLQVSTAEDNG-ILLYNG-----
------------DNDHIAVELY----QGHVRVSYDPGSYPSSAIYS-------TETINDGQFHTVELVTFDQMVN-LSID
GG------SPMTMDNFGKHYTLNSDAP--------------------------------LYVG----------GMPVDVN
SAAFR-----LWQILNGTSFHGCIRNLY-------------------INNELQDFTK-----------------TRMKPG
VVPGCEP-----------CRKLYCLHGICQPNATPGPVCHCEAGWGGLHCDQPA---------------DGPCHGHKCVH
GK-CVPLD------------------------------ALSYSCQCQDGYSGALCNQAGA--------------------
-----------PADPCEGLRCLHGHCQASATKGTYCVCDPGFSGEL-CEQ--ESE---------CRGDPVRDFHQVQRGY
AICRTTRPLSWVECRGSCP---------------------------GQGCCQGLRLKRRKFTFECSDGTSFAEEVEKPTK
CGCALCA-------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------
>Equus_caballus_SLIT1
--------------------------------------------------------------------------------
-------------------------------------------------MALTPRRGPSAGLARPELWLLL-WAAAWRLG
-ATACP-------------------------------------ALCTCTGTTVDCHGTGLQAIPKNIPRNTERLELN---
GNNITRIHKNDFAGLKQLRVLQLMENQIGVVERGAFDDMKELERLRLNRNLLHTLPELLFQNNQALSRLDLSENTIQAIP
RKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNISTIPVSSFN-HMPKLRTFRLHSNHLFCDCHL-WLSQ
WLRQ-RPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSG---QGEAGRVPSCTLSSGSCPAMCTCSNGIVDCRGKGLTAIP
ANLPET-MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQG-LRSLNS-LVLYGNKITDLPRGVFGGLY
TLQLL-LLNANKINCIRPDAFQDLQN--LSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN---PFICDCNLKWLADFLR
TNP-IETSGARCASPRRLANKRIGQIKSKKFRCSAK-EQYFIPGTEDY--QLNSECNSDVVCPHKCRCEASMVECSSLKL
TKLP----ERVPQSTAELRLNNNEISILEATGMFKKLNHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSG
MFRGLDGLRTL-MLRNNRISCIHNDSFTGLRNVRLLSLYDNQIATISPGAFDTLQALSTLNLLANPFNCNCQLAWLGDWL
RKR--KIVTGNPRCQQPDFLRQIP---LQDVAFPDFRCEE-------GREEGGCLPRP-QCPQECACLDTVVRCSNKHLQ
ALPKG-IPKNVTELYLDGN-QFTLVPGQL-STFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQG
LRSLR-LLSLHGNDISTLREGIFADVTSLSHL----AIGANPLYCDCHLRWLSS-WVK--TGYKEPGIARCAG---PPDM
EGKLLLTTPAKKFECQG-------PPTLAVQAKCDPCLSSPCQNQGTCHDD-PLEVYRCACPSGYKGRDCEVSLDSCSSG
PCGNGGTCHPQEG-EEAGFTCSCPTGFEGPTCGVNTDDCVEHAC-ANGGICVDGVGNYTCQ-------------------
---CPLLYSGR---------ACEQLVDFCSPDLNPCQHEAQCVGTPDGPR---------CECAPG---YTGDNCSENQDD
CRDHGCQNG--------AQCMDEVN---SYSCVCA-----EGYSGQLCETPPRPPAPR---SPCEGTECQNGADCVDQ-G
SR---------PVCQCLPGFGGPECEKLLSVNF----VDRDTYLQFTDLQNWPRANITLQVSTAEDNG-ILLYNG-----
------------DNDHIAVELY----QGHVRVSYDPGSYPSSAIYS-------AETINDGQFHTVELVTLDQMVN-LSID
GG------SPMTMDNFGKHYTLNSEAP--------------------------------LYVG----------GMPVDVN
SAAFR-----LWPILNGSSFHGCIRNLY-------------------INNELQDFTK-----------------TRMKPG
VVPGCEP-----------CRKLYCLHGICQPNATPGPVCHCEAGWGGLHCDQPA---------------DGPCHGHKCVH
GK-CVPLD------------------------------ALSYSCQCQDGYSGALCNQAGA--------------------
-----------PADPCGGLQCLHGHCQASATKGAHCVCDPGFSGEL-CEQ--ESE---------CRGDPVRDFHQVQRGY
AICQTTRPLSWVECRGSCP---------------------------GQGCCQ----------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------
>Loxodonta_africana_SLIT1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------DLSENTIQAIP
RKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFN-HMPKLRTFRLHSNHLFCDCHLAWLSQ
WLRQ-RPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSG---QGEAGRVPSCTLSSGSCPAMCTCSNGIVDCRGKGLTAIP
ANLPET-MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQG-LRSLNS-LVLYGNKITDLPRGVFGGLY
TLQLL-LLNANKINCIRPDAFQDLQN--LSLLSLYDNKIQGLAKGTFTSLRAIQTLHLAQN---PFICDCNLKWLADFLR
TNP-IETSGARCATPRRLANKRIGQIKSKKFRCSAK-EQYFIPGTEDY--QLNSECNSDVVCPHKCRCEASVVDCASLKL
TKIP----ERIPQSTAELRLNNNEISILEATGIFKKLTHLKKINLSNNKLSEIEDGAFEGAASVSELHLTANQLESIRSG
MFRGLDSLRTL-MLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTISPGAFDTLQSLSTLNLLANPFNCNCRLAWLGDWL
RKR--KIVTGNPRCQNPDFLRQIP---LQDVAYPDFRCEE-------GQEEGGCLPRP-QCPQECTCLDTVVRCSNKHLR
ALPKG-IPKNVTELYLDGN-QFTLVPGQL-STFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQG
LRSLR-LLSLHGNDISTLRE-IFADVTPFFHIQ---AIGANPLYCDCHLRWLSG-WVK--TGYKEPGIARCAG---PPDM
EGKLLLTTPAKKFECQG-------PPTLAVQAKCDPCLSSPCQNQGTCHND-PLEVYRCACPSGYKGRNCEVSLDGCISG
PCENGGTCLAQEG-DDASFTCSCPTGFEGPTCGVNTDDCVEHAC-ANGGSCVDGVGNYTCQ-------------------
---CPLQYVGK---------ACEQLVDFCSPDLNPCQHDAQCVGTPDGPR---------CECMPG---YTGHNCSENQDD
CGNHRCQNG--------AQCVDEVN---SYSCLCA-----EGYSGQLCEIPPRPPAPR---SPCEGTECQNGANCVDQ-G
SQ---------PVCQCLPGFGGPECEKLLSVNF----VDRDTYLQFTDLQNWPRANITLQVSTAEDNG-ILLYNG-----
------------DNDHIAVELY----QGHVRVSYDPGSYPSSAIYS-------AETINDGQFHTVELVTFDQMVN-LSID
GG------SPMTMDNFDKHYTLNSEAP--------------------------------LYVG----------GMPVDVN
SAAFR-----LWQILNGTSFHGCIRNLY-------------------INNELQDFTK-----------------TQMKPG
VVPGCEP-----------CRKLYCLHGICQPNATPGPVCHCEAGWGGLHCDQPA---------------DGPCHGHKCVH
GN-CVPLD------------------------------ALSYSCQCQDGYSGALCSQAGA--------------------
-----------PADPCGGLRCLHGHCQASATKGSHCVCDPGFSGEL-CEQ--ESE---------CRGDPVRDFHQVQRGY
AICQTTRPLSWVECRGACP---------------------------GQGCCQGLRLKRRKFTFECRDGTSFAEEVEKPTK
CGCALCV-------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------
>Dasypus_novemcinctus_SLIT1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------RDLSENTIQAIP
RKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNISTIPVSSFN-HMPKLRTLITDDLFLCLKNEFGDLGQ
YICLNRPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSG---QGEAGRVAACTLSSGSCPAVCTCSNGIVDCRGKGLTAIP
ANLPEA-MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQG-LRSLNS-LVLYGNKITDLPRGVFGGLY
TLQLL-LLNANKINCIRPDAFQDLQN--LSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN---PFICDCNLKWLADFLR
TNP-IETSGARCASPRRLANKRIGQIKSKKFRCSAK-EQYFIPGTEDY--QLNSECSSDVVCPHKCRCEAGVVECSSLKL
TKIP----ERIPQSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSG
MFRGLEGLRTL-MLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTISPGAFDTLQALSTLNLLANPFNCNCQLAWLGDWL
RKR--KIVTGNPRCQNPDFLRQIP---LQDVAFPDFRCEE-------GQEEGGCLPRP-QCPQECTCLDTVVRCSNKHLR
VLPKG-IPKNVTELYLDGN-QFTLVPGQL-STFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFRG
LRSLR-LLSLHGNDISTLREGIFADVTSLSHL----AIGANPLHCDCHLRWLSG-WVK--TGYKEPGIARCSG---PPDM
EGKLLLTTPAKKFECQG-------PPSLAVQAKCEPCLSSPCQNQGTCHNH-PVEVYRCTCPSGHQGRDCEVSLDSCSSG
PCENGGTCLPQEG-EDAGFTCSCPTGFEGPTCGVNTDNCMEHAC-ANGGTCVDGMGNYTCQ-------------------
---CPPQYVGR---------ACEQLVDFCSLDLNPCQHEAQCVGTPDGPR---------CECAPG---YTGDNCSENQDD
CRDHRCQNG--------AQCVDDVN---SYSCLCA-----EGYSGQLCEIPPRLPASR---SPCEGTECQNGAHCVAQ-G
SR---------PVCQCLPGFGGPECEKLLSVNF----VDRDTYLQFTDLQNWPRANITLQVSTAEDNG-ILLYNG-----
------------DNDHIAVELY----QGHVRVSYDPGSYPSSAIYS-------AETINDGQFHTVELVTFDQMVN-LSID
GG------SPMTMDNFGKHYTLNSEAP--------------------------------LYVG----------GMPVDVN
SAAFR-----LWQVLNGTSFHGCIRNLY-------------------INNELQDFTK-----------------TQMKPG
VVPGCEP-----------CRKLYCLHGICQPNASPGPVCHCEAGWGGLHCDQPA---------------DGPCHGHKCVH
GK-CVPLD------------------------------ALSYSCQCQDGYSGALCNQAGA--------------------
-----------PADPCGGLQCLYGHCQASATKGAHCVCDPGFSGEL-CEQ--GSE---------CRGDPVRDFHQVQRGY
AICQTTRPLSWVQCRGSCP---------------------------GQGCCQGLRLKRRKFTFECSDGTSFAEEVEKPTK
CGCALCA-------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------
>Monodelphis_domestica_SLIT1
--------------------------------------------------------------------------------
--------------------------------------------------MALKHRAGHSAWLRPEVWLLV-WNALCQLC
-ARGCP-------------------------------------ALCTCTGTTVDCHGMGLRAVPKNIPRNTERLELN---
GNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMRELERLRLNRNHLHLLPELLFQNNQALSRLDLSENSIQAIP
RKAFRGATDLKNLQLDKNQISCIEDGAFRALRGLEVLTLNNNNITTIPVSSFN-HMPKLRTFRLHSNHLFCDCHLAWLSQ
WLRQ-RPSIGLFTQCAGPASLRSLNVAEVQKNEFSCSG---PGEATRAPVCTLSSGSCPPMCACSNGIVDCRGKGLTAIP
ANLPET-MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQISEIAPDAFQG-LRSLNS-LVLYGNKITDLPRGVFGGLY
TLQLL-LLNANKINCVRADAFQDLQN--LSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN---PFICDCNLKWLADFLR
TNP-IETSGARCASPRRLANKRIGQIKSKKFRCSAK-EQYFLPGTEDY--QLNSECNSDAICPHKCRCESIVVECSNRKL
NKE---------------RLNNNEISILEATGIFKKLPHLKKINLSNNKVAEIEDGAFEGAASVSELHLTVNQLESIRSG
MFRGLDGLRTL-MLRNNRISCIHNDSFTGLRNVRLLSLYDNQISTISPGAFDTLQSLSTLNLLANPFNCNCQLAWLGDWL
RRR--KIVTGNPRCQNPDFLRQIP---LQDVAFPDFRCEE-------GQEEGGCLPRP-QCPQECTCLDTVVRCSNKHLR
ALPKG-IPKNVTELYLDGN-QFTLVPAQL-STFRYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNSLQCIPPLAFEG
LRSLR-LLSLHGNDISTLREGIFTDVTSLSHL----AIGANPLYCNCHLRWLSS-WVK--TGYKEPGIARCAG---PPDM
EGKLLLTTPAKKFECQG-------PPSIAVQAKCNPCLSSPCQNQGSCQND-PLDSYRCACPSGYKGRDCEMSLNSCSSG
PCENGGTCHSGAG-EGAGFTCSCPMGFEGPTCGVDTDDCRDHTC-ENGGICEDGINNYTCV-------------------
---CPLQYTGR---------ACEQLVDFCSQDLNPCQHGAKCVGTPEGPK---------CECAPG---YIGDNCSINYDD
CTHHQCQNG--------ARCVDEVN---GYSCLCE-----EGYSGQLCEMASQLLKPL---SPCEGAECQNGANCVDL-G
NR---------PVCQCLPGFGGPECEKLLSVNF----VDRDTYLQFTDLQNWPRANITLQVATAEDNG-ILLYNG-----
------------DNDHIAVELY----QGHVRVSYDPGSYPSSAIYS-------AETINDGQFHTVELVTFDQMVN-LSID
GG------SPMTMDNFGKHYTLNREAP--------------------------------LYVG----------GMPVDVN
SAAFR-----LWQILNGTSFHGCIRNLY-------------------INNELQDFTK-----------------TQMKPG
VVPGCEP-----------CRKLYCLHGICQPNAAQGPICHCEPGWGGPHCDQQL---------------GHPCQGHKCVH
GT-CVPLD------------------------------ALSYSCQCQDGYRGALCNQPGE--------------------
-----------PLDPCENLHCLHGHCQISSEGAARCVCRSGFAGEL-CEQ--ARELESPF----CQGDSVWDFHLVQSGY
AICQTTRP----ACRGSCL---------------------------GQGCCTGLRMKRRRFTFECSDGSSFVEDVEKTIK
CGCAGCM-------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------
>Anolis_carolinensis_SLIT1
--------------------------------------------------------------------------------
-------------------------------------------------------MAPRKRAAAPWALLLASWAALGVSG
-ASACP-------------------------------------ALCACSGTTVDCHGLGLRAVPKNIPRGAERLELN---
GNNITRINKHDFAGLKQLRVLQLMENQISVVERGVFDDMKELERLRLNRNQLHTLPELLFQNNQALSRLDLSENLLQAVP
RKAFRGATDLKNLQLDKNHISCIEEGAFRALRGLEVLTLNNNNITTIPISSFN-HMPKLRTFRLHSNQLFCDCHLGWLSQ
WLRQ-RPTIGLFTQCAGPPALRGLNVAEIQKNEFTCTG---QDDATRAQICSFSSGSCPAMCTCSNGIVDCRGKGLTAIP
ANLPET-MTEIRLELNGIKSIPPGAFSSYKKLRRIDLSNNQISELAPDAFQG-LRSLNS-LVLYGNKITELPKGVFGGLY
ALQLL-LLNANKINCIRADTFADLQN--LSLLSLYDNKIQTLAKGTFTTLRAIQTLHLAQN---PFICDCNLKWLADFLR
ANP-IETSGARCASPRRLANKRIGQIKSKKFRCSPK-EQYFIPGTEDY--QLNSECHSDVVCPPKCRCEANVVECSNLKL
TKIP----ERLPQATAELRLNNNEITVLEATGIFKKLPHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLDSVRSS
MFRGLEGLRTL-MLRNNRINCIHNDSFTGLRNVRLLSLYDNQISTISPGAFDTLQSLSTLNLLANPFNCNCRLAWLGDWL
RKR--KIVTGNPRCHNPDFLRQIP---LQDVAFPDFRCEE-------GQEETSCFPRP-QCPQECTCLDTVVRCSNKHLK
ALPKG-IPKNVTELYLDGN-QFTLVPGQL-STFRYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFEG
LRSLR-LLSLHGNDVSMLPEGIFADVTSLSHL----AIGANPLYCDCHMRWLSG-WVK--TGYKEPGIARCAG---PTDM
EGKLLLTTPAKKFECQA-------PPPVAIQAKCNPCLSNPCQNKGTCQQD-PLDSYQCACPNKYKGRNCEFSVDSCSSR
PCENGGTCLSHDG-AGVGFMCFCIDGFEGPTCSLKTNSCNDSSC-KNGGTCITGTSNYTCM-------------------
---CLPFYTGT---------YCEQLVDVCSPELNPCQHGAICRISSEGPK---------CECMPG---YMGDNCSMNYDD
CLDHRCQNS--------AKCLDEPN---GYSCLCA-----GGYSGQLCEIPPHRSLQP---TPCERAECQNGANCVEL-G
SR---------ALCQCLPGFGGPKCEKLLSVNF----VDRDTYLQFTDLQNWPSANITLQVSTAEDNG-ILLYNG-----
------------DTDHMAVELY----QGHVRVSYDPGTYPSSAIYS-------AETINDGQFHTVELVTFERMVN-LSID
GG------DPMTMDGFGKVHTLNPDAP--------------------------------LYVG----------GMPVDVN
SAAFR-----LWQILNGSSFHGCIRNLY-------------------INNELQDFTK-----------------TQMKPG
VVPGCEP-----------CRKLYCLHGICQPNTPHGPICRCDPGWVGPHCDQPI---------------SNPCQGHKCVH
GI-CVPLD------------------------------PLSYSCQCQEDYKGALCNQQGE--------------------
-----------LHNPCKNLQCVHGQCQISDTGEAYCECNGGFDGDL-CDQ--ESE---------CRGEAMRDFHQVQRGY
AICQTTRPVSWVECRGSCP---------------------------GPGCCVGLRLKRRKYTFECSDGSSFVEEVEKPSK
CGCSQCM-------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------
>Xenopus_tropicalis_SLIT1
--------------------------------------------------------------------------------
---------------------------------------------------MDAKGSPTFPLWLRAGVWILAWSWICQVC
-ANGCP-------------------------------------ALCTCSGTTVDCHGLALKGVPKNIPRSTERLELY---
GNNITRINKNDFSGLKQLRVLQLMENQISNVERGAFDDMKELERLRLNRNQLHTLPELLFQNNQALSRLDLSENLIQAIP
RKTFRGATELKNLQLDKNQISCIEDGAFRALRGLEVLTLNNNNITAIPVSSFN-HMPKLRTFRLHSNNLFCDCHLAWLSQ
WLRQ-RPTIGLFTQCTGPSPLRGLNVAEIQKHEFSCSG---QSDPPSSQICSLSIGSCPAMCTCSNGIVDCRGKGLTAIP
ANLPET-MTEIRLELNGIKSVPPGAFSPYKKLRRIDLSNNQISEIAPDAFQG-LRSLNS-LVLYGNKITDLPKGVFSGLH
ALQLL-LLNANKINCIRADTFQDLQN--LSLLSLYDNKIQSLAKGTFAALRAIQTLHLAQN---PFICDCNLKWLADFLR
TNP-IETSGARCASPRRLANKRIGQIKSKKFRCSAK-EQYFIPGTEDY--QLNSECNSDVVCPPKCRCESNVVDCSNLKL
TKIP----DRIPQSTAELRLNNNEIATLEATGLFRKLPHLKKINLSNNKISEIEDAAFEGAASVSELHLTANHLESVRSG
MFRGLEGLRTL-MLRNNRVSCVHNDSFTGLRNVRLLSLYDNQISTITPGAFDTLQSLSTLNLLANPFNCNCQLAWLGDWL
RKR--KIVTGNPRCQNPDFLRQIP---LQDVAFPDFRCED-------GQEELSCAPQP-QCPQECTCLDTVVRCSNKHLL
SLPKG-IPKNVTELYLDGN-QFTMVPGQL-SSFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNSLQCIPPLAFEG
LRSLR-LLSVHGNDISSLPEGIFSDVTSLSHL----AIGANPLYCDCNLRWLSN-WVK--TGYKEPGIARCTG---PPEM
DGKLLLTTPAKKFECNG-------PPSLNILAKCNPCLSDPCKNQGTCQDD-AVQYYKCVCPAGFKGKNCEISLNACSSN
PCENQGLCLSKE--EGSGFMCTCADGFEGPTCAVNKDDCKYSDC-ENGGTCLDGINNYTCL-------------------
---CPSQYTGE---------YCEHLVDICSTDLNPCHSDSKCTVTPEGPK---------CECAPG---YGGDDCSLNYDD
CKDHRCQNN--------ALCVDEVN---GYSCLCT-----EGYSGQLCEMP---SQAP---SPCKLTPCQNGANCIEV-G
NS---------AVCQCLPGFGGSKCEKLLSVNF----VDRDTYLQFTDLQNWPRANITLQVSTAEDNG-ILLYNG-----
------------DHDHMAVELY----QGHVRVSYDPGSFPSSAIYS-------AETINDGQFHTVELVTFDQMVN-LSID
GG------APMTMDKFGKHYTLNSEAP--------------------------------LYVG----------GMPVDVN
SAAFR-----LWQILNGTSFHGCIRNLY-------------------INNELQDFTK-----------------TQMKPG
VVPGCEP-----------CRKLFCLHGICQPNAANGPVCHCETGWAGPHCDQQL---------------NDPCQGHKCVH
GA-CMPLD------------------------------ALTYSCLCQDGYKGALCNQQGE--------------------
-----------LYNPCKTLQCQHGRCQISDLGEAYCECESGYVGDN-CDQ--ESE---------CRGEPVRDYYQVQRGY
AICQTTRTVSWVECRGSCH---------------------------NQGCCTGLRMKRRKYTFECSDGSSFVEDVEKPIK
CGCAQCV-------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------
>Danio_rerio_SLIT1_a
--------------------------------------------------------------------------------
----------------------------------------------------------MPARGGCCLLEVCVWVLLLVCK
TGSGCP-------------------------------------ALCTCSGTTVDCHGLGLKNIPRNIPRNTERLELN---
GNNLTRINRNDFTGLKYLRVLQLMENQIVTVERGAFDEMRELERLRLNRNQLHQLPELLFQKNAALSRLDLSENFIQAIP
RKAFRGATDIKNLQLDKNHISCIEDGAFRAMRGLEVLTLNNNNISSIPVSSFN-HMPKLRTFRLHSNNLVCDCVLSWLSQ
WLRE-RPNIGLFTQCSSPAPLRGLNVAEVQKHEFSCSG---QSDSAVGQSCSLSSGSCPAVCSCNNNIVDCRGKGLTLIP
SSLPDS-MTEIRLEQNSIKSIPPGAFSPYKKLRRIDLSNNQISELAPDAFQG-LRSLNS-LVLYGNKITDLPRGVFDGLH
ALQLL-LLNANKIHCLRANTFQDLQN--LSLLSLYDNKIQTLAKGTFSSLRAIQTLHLAQN---PFICDCNLKWLADYLR
SNP-IETSGARCTSPRRLANKRIGQIKSKKFRCSAK-EQYVIPGTEDS--RLNNDCNNDPVCPAKCRCESNVVDCSNLRL
DRIP----EHIPASTTELRLNNNEITTIEAMGAFKTLTHLKKINLSNNKISEIEDGAFEGASSVNELHLTANQLDSVHSR
MFRGLEGLRML-MLRNNRISCIHNNSFTGLHNVRLLSLYDNTLTTIAPGAFDTLQSLSTLNLLANPFNCNCRLAWLSSWL
RNR--KIVTGNPRCHRPAFLKEIP---LQDVAAPDFRCED-------DHEDVSCAPPV-HCPADCTCLESVVRCSNKHLQ
ALPKG-IPRNITELYLDGN-QLSTVPKEL-SSFKSLQLVDLSNNRISSLTNSSFTNMSQLTTLILSYNALRCIPTLAFSG
LRSLR-LLSLHGNDISELPDGIFSDAQSLSHL----AIGANPLHCDCGLRWLSD-WVK--TGYKEPGIARCAS---PHGM
EGKLLLTTPAKRFECQG-------EVDSAILAKCNPCASGPCLHQGVCEAD-QTDGYRCRCADGFKGKNCETVVNACVSE
PCKNGGTCHVSTD-EDEGYSCSCAAGFEGPSCEVDTDECRDNDC-QNGATCIDGINNYTCL-------------------
---CAPFYTGE---------MCEDLEDMCSSARSPCKQQSTCFITVTGPK---------CICAAG---YVGEDCSVNYDD
CKDHRCQNG--------AQCVDELN---GYSCVCQ-----KGYSGQLCEVA---PPPR---SPCERADCQNNAPCVER-A
GH---------PLCQCLEGFGGPRCEKLVSVNF----VDRDSYLLLSDLKNWPQANITLQVSTAEDNG-ILLYNG-----
------------DNDHIAVEIH----EGHVKVSYDPGSQQSHAIYS-------TETVNDGQFHTVELVTFDQMVN-LSID
GG------SPTTMDSFGKVQPLRGEAP--------------------------------LYVG----------GMPVSVH
PTAPR-----VWQIQNSSSFHGCIQNLY-------------------INNELQDFTK-----------------TQMKPG
VVPGCEP-----------CRKIYCLHGICQPNTATGPVCHCQPGWSGQHCDQPL---------------ANPCMGSKCVH
GR-CIPMD------------------------------MQSYRCECQEGFHGALCNQHEE--------------------
-----------LFNPCRKLQCKHGHCQISDTGDAYCHCEPGYSGDL-CDR--ESE---------CRGEPVRDFYQVQRGY
SICQTTRMVSWVECSGVCE---------------------------SGSCCASQRMKRRKYSFECSDGTSFSEEVEKTIK
CGCVGCM-------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------
>Takifugu_rubripes_SLIT1_b
--------------------------------------------------------------------------------
--------------------------------------------LVNMPLRGNRFGAFLCRQAGRPLWMWLVMLSALLMG
NAGACP-------------------------------------ALCTCSGTTVDCHGLGLRTMPRNIPRNAERLELN---
GNNLTRITKSDFAGLKYIRVLQLMENQITVIERGAFDDMKELERLRLNRNQLQQLPELLFQKNPALSRLDLSENFIQSIP
RKAFRGATDIKNLQLDKNHIGCIEDGAFRAMRGLEVLTLNNNNISSIPVSSFN-HMPKLRTFRLHSNNLHCDCHLGWLAQ
WLRQ-RPTVGLFTQCTSPAELRGLNVAEVQKHEFSCSG---HQESFATQACSVGGGSCPAMCTCSNNIVDCRGKGLTAIP
ANLPES-MAEIRLEQNGIKSVPPGAFSPYKKLRRIDLSNNQISEIAPDAFQG-LRSLNS-LVLYGNKITDLPKGVFDGLY
ALQLL-LLNANKIHCVRANAFQDLQN--LSLLSLYDNKIQTLAKGTFTSLRAIQTLHLAQN---PFICDCNLKWLADYLR
SNP-IETSGARCASPRRLANKRIGQIKSKKFRCSAK-EQYFIPGTEDT--RLSNACNSDPVCPPKCRCESNVVDCSNLKL
TKIP----EHIPSSTNELRLNNNDITTLEASGAFKSLSQLKKINLSNNKITEIEDGAFEGASSVIELHLTANQIDSVRSS
MFRGLEGLRML-MLRNNKISCVHNDSFTGLHNVRLLSLYDNQLTTITPGAFDTLQALSTLNLLANTFNCDCRLAWLGDWL
RSR--KIVTGNPRCQRPGFLKEIP---LQDVAQPDFRCDE-------GQEELSCVPRP-QCPSECTCLETVVRCSNKHLH
ALPKG-IPRNVTELYLDGN-QFSIVPKEL-SGFKYLQLVDLSNNRINSLTNSSFSNMSQLTTLILSYNSLRCIPKMAFGG
LHSLR-LLSLHGNEISELPDGIFNDVTSLSHL----AIGANPLYCDCRLRWLSD-WVK--TGYKEPGIARCAG---PQGM
EGKLLLTTPAKKFECTG-------DVDPEVLAKCNPCLSSPCLNQGVCHSD-LMEIYRCSCPPGFKGKNCETALNACVSG
PCANGGTCRVEAEGDYTHHSCKCPLGFEGPTCQTNTDECEDHDC-ENGATCIDGVNNYTCF-------------------
---CPPYYTGE---------MCEEMEDVCAPGRSPCKHQSTCLIAPTGPK---------CVCAPG---YVGDDCSVDYND
CEDHRCQNG--------AHCVDELN---GYSCVCR-----QGYSGQLCEVP---PSPL---SLCELADCQNSAPCVER-G
GR---------ALCQCPPEFGGPRCEKLVSVNF----VDRDSYLLLSDLKNWPQANITLQVSTAEDNG-ILLYNG-----
------------DNDHIAVELY----QGHVKVSYDPGSQPGHAIYS-------TETINDGQFHTVELVTFDQMVN-LSID
GG------LPTTMDSFGAVRTLNGEAP--------------------------------LYVG----------GMPVDVH
AGTFR-----LWQIQNGSSFHGCIQNLY-------------------INNELQDFTK-----------------TQMKPG
VVPGCEP-----------CKKIYCVHGICQPDGIQGPVCHCQPGWSGPHCDEPA---------------ANPCQGSKCVH
GR-CIPLD------------------------------SQSYRCECDEGYRGALCNQEGE--------------------
-----------LFNPCRRLSCKHGRCQISDTGDAFCNCESGYTGEL-CDA--ESE---------CRGEPMRDFYQVQRGY
AICQTTRMVSWVECSGVCD---------------------------KGACCASQRMKRRKYTFECSDGTSFSEEVEKTIK
CGCVGCM-------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------
>Tetraodon_nigroviridis_SLIT1_a
--------------------------------------------------------------------------------
-----------------------------------------------FPLSPGEQ-----SEAG-PLWMWLVMLSALLMG
NVGACP-------------------------------------ALCTCSGTTVDCHGLGLRSMPRNIPRNAERLELN---
GNNLTRITKSDFAGLKYIRVLQLMENQITVIERGAFDDMKELERLRLNRNQLQQLPELLFQKNPALSRLDLSENFIQSIP
RKAFRGATDIKNLQLDKNHIGCIEDGAFRAMRGLEVLTLNNNNISSIPVSSFN-HMPKLRTFRLHSNNLHCDCHLAWLAQ
WLRQ-RPTVGLFTQCTLPAELRGLNVAEVQKHEFSCSG---HQDSSGLQACSVGGGSCPAMCTCSNNIVDCRGKGLTAIP
ANLPES-MAEIRLEQNGIKSVPPGAFSPYKKLRRIDLSNNQISEIAPDAFQG-LRSLNSLLCVYGNKITDLPKGVFDGLY
ALQLL-LLNANKIHCIRANAFQDLQN--LSLLSLYDNKIQTLAKGTFTSLRAIQTLHLAQN---PFICDCNLKWLADYLR
SNP-IETSGARCASPRRLANKRIGQIKSKKFRCSAK-EQYFIPGTEDT--RLNNACNSDPVCPPKCRCESNVVDCSNLKL
TKVP----EHIPSSTSELRLNNNDITTLEATGAFKSLSQLKKINLSNNKITEIEDGAFEGASSVIELHLTANQIDSVRSG
MFRGLEGLRMM-MLRNNKISCVHNDSFTGLHNVRLLSLYDNQLTTITPGAFDTLQALSTLNLLANSFNCDCRLAWLGDWL
RSR--KIVTGNPRCQRPGFLKEIP---LQDVALPDFRCDEA------GQEESSCVPRP-QCPSECTCLETVVRCSNKHLH
ALPKG-IPRNVTELYLDGN-QFSIVPKEL-SGFKYLQLVDLSNNRINSLTNSSFSNMSQLTTLILSYNSLRCIPKMAFGG
LHSLR-LLSLHGNEISELPDGIFNDVTSLSHL----AIGANPLYCDCRLRWLSD-WVK--TGYKEPGIARCAG---PQGM
EGKLLLTTPAKKFECTG-------DVDPEVLAKCNPCLSSPCLNQGVCQSD-LMEIYRCSCPPGFKGKNCETALNACVSN
PCANGGTCRVDEE-EEGEYICKCPLGFEGPTCQTNADDCEDHDC-ENGATCVDGVNNYTCF-------------------
---CPPYYTGE---------MCEEMEDVCAPERSPCKHQSTCLITPTGPK---------CVCSPG---YVGDDCSVDYND
CGDHRCQNG--------AQCIDELN---GYSCVCH-----QGYSGQLCEVP---PSPL---SLCELADCQNNAPCVER-G
GR---------ALCQCPPEFGGPRCEKLVSVNF----VDRDSYLLLSDPKNWPQANITLQVSTAEDNG-ILLYNG-----
------------DNDHIAVELY----QGHVKVSYDPGSQPGHAIYS-------TETINDGQFHTVELVTYDQMVN-LSID
GG------LPTTMDSFGAVRTLNGEAP--------------------------------LYVG----------G------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------
>Tetraodon_nigroviridis_SLIT1_b
--------------------------------------------------------------------------------
---------------------------------------------------SGGGSSAAGCLPRVQLAWAAALLLVPWGG
GVEACP-------------------------------------SPCSCLGATVDCHGRGIHAVPKNIPRATERLDLN---
GNNLTVISRTDFAGLRHLRVLHLMENQIVAVERGAFDELKELERLRLNRNRLGQIPELLFQKNEALTRLDLSENVLQAIP
RRTFRGATELKNLQLDKNHISCIEEGAFRALRTLEVLTLNNNNISSIPVSSFN-HMPKLRTFRLHSNSLRCDCHLA-LSP
WLRQ-RASLGLYAQCSSPPSLRGLNLAELRKSDLACSG-----EAPPPGPCSLASGSCPPMCTCSNNIVDCRGRGLTAIP
AHLPEA-MTEIRLEQNGIKSVPPGAFSSYKKLRRIDLSNNQIAEMAPDAFQG-LRALSS-LVLYGNKIAELPAGVFDGLS
SLELL-LLNANRIHCIRASLFKDLEN--LALLSLYDNRIQSLAKGTFGSLRSIQTLHLAQN---PFVCDCHVRWLAEFLR
ANP-IETSGARCASPRRLANKRIAQ-KSSKFRCSEKSPAYNNP-------RSSTSSQANRLCP------ANVVDCDNQRL
TLFQPPPDQLPP-TPASQRLNNNDLSVLEATGAFKGLSQLKKINLSNNKISEIEDGAFEGAASVVELHLTANHLDAVRGS
MFKGMEGLRML-MLRNNKISCLHNGSFTGLNNVRLLSLYDNQLSTILPGAFDTLPNLSTLNLLANPFNCDCRLSWFGAWL
RSR--RIVTGNPRCQSPAFLREIP---LQDVAAPDFRCEDGA-----AQEEAGCGLGP-QCPSQCTCMDSVVRCSNKHLQ
ALPRG-LPRNVTELYLDGN-QFTSVPKEL-ATFRFLQLVDLSNNKISFLSDDSFSNMSQLTTLWRLQTLSAASPLLALSG
LRSLQIWLSLHGNDISELTDRASYSRRAPSLSHSVRAIGANPLYCDCRLLWLSD-WVK--SGYKEPGIARCAG---PGGV
EGKLLLTAPAHSFQCDG-------PVEPSVRAKCSPCVSSPCQNQGVCKDD-HTQLFTCTCKPGFTGKHCETPVDACVSN
PCTNGGVCLSDEQ--TGGFRCACAFGFHGTFCEVNVDDCQDHGC-ENGATCVDGVGNYTCL-------------------
---CAPSYKGL---------FCEEVDSVCGPGRNPCQHQSTCISTPAGPRILYL-----CNRIPG---WVGPECSIDYNE
CVDHRCQNG--------AECVDHLD---GYSCVCP-----QGFSGQFCEAP---PPPA---SPCQLAQCQNGALCVEA-A
GA---------AACTCAPGFEGQRCEKLVSVNF----LERDSYVQLQDVKNWPHANITLQVSTAEDNG-VLLYNG-----
------------DNEPIAVELH----QGHVRVTYDPGDQPATSIY-----------------------------------
-----------TLEGRGRSQAAAGEAP--------------------------------LYVG----------GLPEEAV
PAAP--------DAVNVSGFHGCIRKLY-------------------INHELQDFTR-----------------SHMGAG
VEPGCQA-----------CRQSYCAHGTCQPDAAQGPRCHCHPGWAGPRCDRPATAEG-----VTVATGVDPCADSRCVQ
GA-CVPVD------------------------------ARTYRCDCRDGYEGALCHLQRQ--------------------
-----------PASWCGRLPCVHGQCERTE-KAERCACEDGFSGQS-CDI--ELP---------CGGQPVRDHHRLRRGS
ALCQTAKPFSWVECRGRCG---------------------------VATCCAPLRLRRRRLSFQCDDGTTFTQDVEKPVE
CGCKECV-------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------
>Gasterosteus_aculeatus_SLIT1_a
--------------------------------------------------------------------------------
----------------------------------------------------------TGRRAG--LWMWVVMLSALLVG
NVSACP-------------------------------------ALCTCSGTTVDCHGLGLKTMPRNIPRTTERLELN---
GNNLTRITKSDFAGLKYIRVLQLMENQITAIERGAFDDMKELERLRLNRNQLQQLPELLFQKNPALSRLDLSENFIQSIP
RKAFRGATDIKNLQLDKNHISCIEDGGFRALRGLEVLTLNNNNISSIPVSSFN-HMPKLRTFRLHSNNLNCDCHLAWLAQ
WLRQ-RPTIGLFTQCTAPSELRGLNVAEVQKHEFSCSG---HQEPGSPQPCSVGVGSCPAMCTCSNNIVDCRGKGLTAIP
ANLPDT-MAEIRLEQNGIKSVPPGAFSPYKKLRRIDLSNNHISEIAPDAFQG-LRSLNS-LVLYGNKITDLPKGVFDGLY
ALQLL-LLNANKIHCVRANAFQDLQN--LSLLSLYDNKIQTLAKGTFASLRAIQTLHLAQN---PFICDCNLKWLADYLR
SNP-IETSGARCASPRRLANKRIGQIKSKKFRCSAK-EQYFIPGTEDT--RLNNACNSDPVCPPKCRCESNVVDCSNLKL
TKIP----EHIPTSTSELRLNNNDITALEATGVFKSLSQLKKINLSNNKITEIEDGSFEGASAVNELHLTANQIDSVRSG
MFRGLEGLRML-MLRNNKISCVHNDSFTGLHNVRLLSLYDNQLTTITPGAFDTLQTLSTLNLLANSFNCDCRLGWLGDWL
RSR--KIVTGNPRCQRPAFLKEIP---LQDVALPDFRCEEG------QEEPSSCVPRP-QCPSECTCLETVVRCSNKHLH
TLPKG-IPRNVTELYLDGN-QFNVVPKEL-STYKYLQLVDLSNNKINSLTNSSFANMSQLTTLILSYNSLRCIPKMAFSG
LHSLR-LLSLHGNEISELPDGIFNDVASLSHL----AIGANPLHCDCHLRWLSD-WVK--TSYKEPGIARCAG---PQGM
EGKLLLTTPAKKFECTG-------DVDTTVVAKCNPCVSSPCLNHGICHSD-MVEIYRCSCPPGFKGKNCETALDACLSS
PCANRGTCQVNDG-EEGQYSCTCPLGFEGPTCQTNIDECEDNDC-ENGATCLDGVNNYTCF-------------------
---CPPYYTGE---------MCEEMEDVCAPGRSPCKHQSTCLITSNGPK---------CVCSPG---YVGDDCSVDYKE
CEEHRCQNG--------AQCAPFHL---LHHQRRP--LSLGLRSGQLCEFL---PYAL---SLCELADCQNNAPCLER-G
GR---------ALCQCPPEFGGPRCEKLVSVNF----IDRDSYLLLSDLKNWPQANITLQVSTAEDNG-ILLYNG-----
------------DNDHIAVELY----QGHVKVSYDPGSQPGHAIYSS------TETINDGQFHTVELVTFDQMVN-LSID
GG------LPTTMDSFGAVRPLNGEAP--------------------------------LYVG----------GMPVAVH
SGAFR-----LWQLQNGSSFHGCIQNLY-------------------INNELQDFTK-----------------TQMKPG
VVPGCEP-----------CKKIYCVHGICQPDGFQGPVCHCQPGWTGPQCDQTA---------------TNPCQGTKCVH
GK-CIPLD------------------------------PQSYRCECEEGYRGALCNQQGE--------------------
-----------LFNPCRRLSCKHGRCQISDTGEAYCHCESGYTGGL-CDA--ESE---------CRGEPVRDFYQVQRGY
AICQTTRMVSWVECSGACD---------------------------AGACCASQRMKRRKYTFECSDGTSFSEEVEKTIK
CGCVGCM-------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------
>Oryzias_latipes_SLIT1_a
--------------------------------------------------------------------------------
-----------------------------------------------MSITGSCFEAGMGCPAV--QWMWLLMLSALIIG
NASACP-------------------------------------ALCTCSGVTVDCHGLGLKTMPRNIPRNTERLELN---
GNNLTRITKSDFTGLKYVRVLQLMENQITVVERGAFDDMKELERLRLNRNQLQQLPELLFQKNPALSRLDLSENFIQSIP
RKAFRGATDIKNLQLDKNHISCIEDGAFRAMRGLEVLTLNNNNISSIPVSSFN-HMPKLRTFRLHSNNLNCDCHLAWLAQ
WLRQ-RPTIGLFTQCTVPSELKGLNVAEVQKHEFTCSG---HQESSSLQPCSIGGGSCPAMCTCSNNIVDCRGKGLTAIP
ANLPDN-MAEIRLEQNGIKSVPPGAFSSYKKLRRIDLSNNQISEIAPDAFQG-LRSLNS-LVLYGNKITDLPKGVFDGLY
ALQLL-LLNANKIHCIRANTFQDLQN--LSLLSLYDNKIQTLAKGTFTSLRAIQTLHLAQN---PFICDCNLKWLADYLR
SNP-IETSGARCASPRRLANKRIGQIKSKKFRCSAK-EQYVIPGTEDV--RLNDACNSDPVCPPKCRCESNVVDCSNLKL
TKIP----EHIPSSTSELRLNNNEITSLDANGAFKNLAQLKKINLSNNKITEIEDGTFEGASAVIELHLTANQIDSVRSG
MFRGLEGLRML-MLRNNKISCVHNDSFTGLHNVRLLSLYDNQLTTITPGAFDTLQTLSTLNLLANSFNCDCRLAWLGDWL
RSR--KIVTGNPRCQRPAFLKEIP---LQDVALPDFRCDEG------QEE-SSCIPRP-QCPSECTCLETVVRCSNKHLH
SLPRG-IPRNVTELYLDGN-QFSIVPKEL-STFKYLQLVDLSNNKINSLTNSSFANMSQLTTLILSYNSLRCIPKMAFSG
LHSLR-LLSLHGNEISELPDGIFNDVASLSHL----AIGANPLHCDCRLRWLSD-WVK--TGYKEPGIARCAG---PQGL
EGKLLLTTPAKKFECHG-------DVDIAVLSKCNPCLSNPCMNHGICHND-PVEIYRCSCPPGFKGKNCESGLNACVSN
PCANGGTCRVHED-NEGQYSCTCALGFEGPTCKINTDDCEDNDC-ENGATCVDGINNYTCF-------------------
---CPPYYTGE---------MCEEMEDVCAPGRSPCQHQSTCLITSSGPK---------CVCSPG---YVGDDCSIDYND
CEEHRCQNG--------AQCVDELS---GYSCICPKGFRVSPRSGQLCEVP---PSPL---SLCELADCQNDAPCVER-G
GR---------ALCQCPPEFGGPRCEKLVSVNF----IDRDSYLLLSDLKNWPQANITLQVSTAEDNG-ILLYNG-----
------------DNDHIAVELF----QGHVKVSYDPGSQPGHAIYS-------TETINDGQFHTVELVTFDQMVN-LSID
GG------LPTTMDSFGAVRPLNREAP--------------------------------LYVG----------GMPVDVH
SGTFR-----LWQIQNSSSFHGCIQNLY-------------------INNELQDFTK-----------------TQMKPG
VVPGCEP-----------CKKLYCVHGICQPDGAQGPVCHCQPGWIGAHCDQPA---------------LNPCQGSKCVH
GK-CIPLD------------------------------AQSYRCECQEGYRGALCNQQGE--------------------
-----------LFNPCRRLSCKHGRCQISDAGSAYCHCESGYTGEL-CDA--ESE---------CRGEPVRDFYQVQRGY
AICQTTRMVSWVECSGACS---------------------------TGACCGSQRMKRRKYTFECSDGTSFSEEVEKTIK
CGCVGCM-------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------
>Oryzias_latipes_SLIT1_b
------------------------------------------------------------------