>Homo_sapiens_RUFY3
--------------------------------------------------------------------------------
MSALTPP----------------------------------TDMPTPTTDKITQ------------AAMETIYLCKFRVS
MDG-------EWLCLRELDDISLTPDPEP-----------------THED------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------PN
YLMANERMNLMNMAK-----------------LSIKGL------IESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLK--
--------------------AKKTFLG-QNKSFWGPLELVEKLV------------------------------------
------------------PEAAEITASVKDLPG-LKTPVGRG--------------------------------------
------------------------------RAWLRLALMQKKLSEYMKALINKKELL---------------------SE
FYEPNALMMEEEGAIIAG---------------------------------------------------------LLVGL
NVIDAN----------------------------------------------------------FCMKGEDLDSQ-VGVI
DFSMYLKDG-NSSKGTE-G------------DGQITAILDQKNYVEELNRHL-----------NATVNNLQAKVDALEKS
NTKLTEELAVANN-RIITLQEEMERVKEESSYILESNR-----------------KGPKQDRTAEGQALS----------
-------EARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLRALKHELAFKLQ---
-----------SSDLGVKQKSELNSRLEEKTNQMAATIKQLEQRLRQAERSRQSAELDNRLFKQDFGDKINSLQLEVEEL
T--------------RQRNQLELELKQEKE------------------------RRLQNDRS-IPGRGSQK-SESKMDGK
HKMQEEN------------VKLKKPLEESHRLQPHP-MDEQ-DQLLLSEKP--------QLCQL----------------
-----------CQEDG---SLTKNVCKNCSGTFCDACSTNELPLPSSIKLERVCNPCHKHLMKQYSTSPS----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Pongo_abelii_RUFY3
--------------------------------------------------------------------------------
MSALTPP----------------------------------TDMPTPTTDKITQ------------AAMETIYLCKFRVS
MDG-------EWLCLRELDDISLTPDPEP-----------------THED------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------PN
YLMANERMNLMNMAK-----------------LSIKGL------IESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLK--
--------------------AKKTFLG-QNKSFWGPLELVEKLV------------------------------------
------------------PEAAEITASVKDLPG-LKTPVGRG--------------------------------------
------------------------------RAWLRLALMQKKLSEYMKALINKKELL---------------------SE
FYEPNALMMEEEGAIIAG---------------------------------------------------------LLVGL
NVIDAN----------------------------------------------------------FCMKGEDLDSQ-VGVI
DFSMYLKDG-NSSKGTE-G------------DGQITAILDQKNYVEELNRHL-----------NATVNNLQAKVDALEKS
NTKLTEEXAVANN-RIITLQEEMERVKEESSYILESNR-----------------KGPKQDRTAEGQALS----------
-------EARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLRALKHELAFKLQ---
-----------SSDLGVKQKSELNSRLEEKTNQMAATIKQLEQRLRQAERSRQSAELDNRLFKQDFGDKINSLQLEVEEL
T--------------RQRNQLELELKQEKE------------------------RRLQNDRS-IPGRGSQK-SESKMDGK
HKMQEEK------------VKLKKPLEESHRLQPHP-MDEQ-DQLLLSEKP--------QVCQL----------------
-----------CQEDG---SLTKNVCKNCRGTFCDACSTNELPLPSSIKLERVCNPCHKHLMKQYFTSPS----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Macaca_mulatta_RUFY3
--------------------------------------------------------------------------------
MSALTPP----------------------------------TDMPTPTTDKITQ------------AAMETIYLCKFRVS
MDG-------EWLCLRELDDISLTPDPEP-----------------THED------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------PN
YLMANERMNLMNMAK-----------------LSIKGL------IESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLK--
--------------------AKKTFLG-QNKSFWGPLELVEKLV------------------------------------
------------------PEAAEITASVKDLPG-LKTPVGRG--------------------------------------
------------------------------RAWLRLALMQKKLSEYMKALINKKELL---------------------SE
FYEPNALMMEEEGAIIAG---------------------------------------------------------LLVGL
NVIDAN----------------------------------------------------------FCMKGEDLDSQ-VGVI
DFSMYLKDG-NSSKGTE-G------------DGQITAILDQKNYVEELNRHL-----------NATVNNLQAKVDALEKS
NTKLTEELAVANN-RIITLQEEMERVKEESSYILESNR-----------------KGPKQDRTAEGQALS----------
-------EARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLRALKHELAFKLQ---
-----------SSDLGVKQKSELNSRLEEKTNQMAATIKQLEQRLRQAERSRQSAELDNRLFKQDFGDKINSLQLEVEEL
T--------------RQRRQDPFPDKKKKK------------------------KKLLS--F-IP--KLRH-CRRKYDGK
HNMQEEN------------VKLKKPLEESHRLQPHP-TDEQ-DQLLLSGKP--------QVCQL----------------
-----------CQEDG---SLTKNVCKNCRGTFCDACSTNELPLPSSIKPERVCNPCHKHLMKQYSTSPS----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Mus_musculus_RUFY3
--------------------------------------------------------------------------------
MSALTPP----------------------------------TDMPTPTTDKITQ------------AAMETIYLCKFRVS
MDG-------EWLCLRELDDISLTPDPEP-----------------THED------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------PN
YLMANERMNLMNMAK-----------------LSIKGL------IESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLK--
--------------------AKKTFLG-QNKSFWGPLELVEKLV------------------------------------
------------------PEAAEITASVKDLPG-LKTPVGRG--------------------------------------
------------------------------RAWLRLALMQKKLSEYMKALINKKELL---------------------SE
FYEVNALMMEEEGAIIAG---------------------------------------------------------LLVGL
NVIDAN----------------------------------------------------------FCMKGEDLDSQ-VGVI
DFSMYLKDG-NSSKGSE-G------------DGQITAILDQKNYVEELNRHL-----------NATVNNLQTKVDLLEKS
NTKLTEELAVANN-RIITLQEEMERVKEESSYLLESNRK-----------------GPKQDRTAEGQALS----------
-------EARKHLKEETQLRLDVEKELELQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLRALKHELAFKLQ---
-----------SSDLGVKQKSELNSRLEEKTNQMAATIKQLEQ----SEKD---------LVKQAK-----TLNSAANKL
I--------------PKHH-------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Rattus_norvegicus_RUFY3
--------------------------------------------------------------------------------
MSALTPP----------------------------------TDMPTPTTDKITQ------------AAMETIYLCKFRVS
MDG-------EWLCLRELDDISLTPDPEP-----------------THED------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------PN
YLMANERMNLMNMAK-----------------LSIKGL------IESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLK--
--------------------AKKTFLG-QNKSFWGPLELVEKLV------------------------------------
------------------PEAAEITASVKDLPG-LKTPVGRG--------------------------------------
------------------------------RAWLRLALMQKKLSEYMKALINKKELL---------------------SE
FYEANALMMEEEGAIIAG---------------------------------------------------------LLVGL
NVIDAN----------------------------------------------------------FCMKGEDLDSQ-VGVI
DFSMYLKDG-NSSKGSE-G------------DGQITAILDQKNYVEELNRHL-----------NATVNNLQAKVDALEKS
NTKLTEELAVANN-RIITLQEEMERVKEESSYLLESNRK-----------------GPKQDRTAEGQALS----------
-------EARKHLKEETQLRLDVEKELELQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLRALKHELAFKLQ---
-----------SSDLGVKQKSELNSRLEEKTNQMAATIKQLEQ----SEKD---------LVKQAK-----TLNSAANKL
I--------------PKHH-------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Felis_catus_RUFY3
--------------------------------------------------------------------------------
MSALTPP----------------------------------TDMPTPTTDKITQ------------AAMETIYLCKFRVS
MDG-------EWLCLRELDDISLTPDPEP-----------------THED------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------PN
YLMANERMNLMNMAK-----------------LSIKGL------IESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLK--
--------------------AKKTFLG-QNKSFWGPLELVEKLV------------------------------------
------------------PEAAEITASVKDLPG-LKTPVGRG--------------------------------------
------------------------------RAWLRLALMQKKLSEYMKALINKKELL---------------------SE
FYEPNALMMEEEGAIIAG---------------------------------------------------------LLVGL
NVIDAN----------------------------------------------------------FCMKGEDLDSQ-VGVI
DFSMYLKDG-NSSKGSE-G------------DGQITAILDQKNYVEELNRHL-----------NATVNNLQAKVDALEKS
NTKLTEELAVANN-RIITLQEEMERVKEESSYILESNR-----------------KGPKQDRTSDGQALS----------
-------EARKHLKEETQLRLDVEKELEIQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLRALKHELAFKLQ---
-----------SSDLGVKQKSELNSRLEEKTNQMAATIKQLEQRLRQAERDRQSAELDNRLFKQDFGDKINSLQLEVEEL
T--------------RQRHQLELELKQERE------------------------RRLQNNRN-IPGKGFQK-PEPKTDGK
HRIQEEN------------AKLKKPLDESHRCLLIK-YDIN-DQPLLSAKP--------QMCQL----------------
-----------CQQDG---RLAKNMCKNCRGTFCDACSTNELPLPSSIKPERVCNPCHEHLMKQYSASPS----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Bos_taurus_RUFY3
--------------------------------------------------------------------------------
MAETSPPPTAGAESCSEEPARGGKQRPEEPRRAPAGGADREDEAGPPLASPAGQ------------SEPGSPVAAPFFLL
YPGDGGAGFVARPPPQQQRSWRTPPSPGSPLPFLLLNYPSGGGGGGGKHH------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------PN
YLMANERMNLMNMAK-----------------LSIKGL------IESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLK--
--------------------AKKTFLG-QNKSFWGPLDIVRRAL------------------------------------
------------------VIALWISASESQETR-SRTPVGRG--------------------------------------
------------------------------RAWLRLALMQKKLSEYMKALINKKELL---------------------SE
FYEPNALMMEEEGAIIAG---------------------------------------------------------LLVGL
NVIDAN----------------------------------------------------------FCMKGEDLDSQ-VGVI
DFSMYLKDG-NSSKGSE-G------------DGQITAILDQKNYVEELNRHL-----------NATVNNLQAKVDALEKS
NTKLTEELAVANN-RIITLQEEMERVKEESSYILESNR-----------------KGPKPDRTSEGQALS----------
-------EARKHLKEETQLRLDVEKELEIQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLRALKHELAFKLQQ--
-----------SSDLGVKQKSELNSRLEEKTNQMAATIKQLEQRLRQAERGRQSAELDNRLFKQDFGDKINSLQLEVEAL
T--------------RQRNHLELELKQERE------------------------RRLQNSRS-IPGKGSQKPEEPKMDGK
HKIQEEN------------VKLNKPLEESHRLQSHP-VDQQ-DQPLPSEKPP-------KYCQL----------------
-----------CQED---CSLTKNVCRNCRGTFCNICSTNELPLPSSIKPERVCNPCHEHLMKQYSTSPS----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Loxodonta_africana_RUFY3
--------------------------------------------------------------------------------
MAETPSPPSAGAESYSEEPVRGGERRPEEPRSAPAGGADRESEAGPPLASPAAQ------------SEPDSPVAAPFFLL
YPGNGGAGFPARLPPQQQRVWRTPPSPGSPLPFLLLSYPSGGGGGGGKHN------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------PN
YLMANERMNLMNMAK-----------------LSIKGL------IESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLK--
--------------------AKKTFLG-QNKSFWGPLELVEKLV------------------------------------
------------------PEAAEITASVKDLPG-LKTPVGRG--------------------------------------
------------------------------RAWLRLALMQKKLSEYMKALINKKELL---------------------SE
FYEPNALMMEEEGAIIAG---------------------------------------------------------LLVGL
NVIDAN----------------------------------------------------------FCMKGEDLDSQ-VGVI
DFSMYLKDG-NSSKGSE-G------------DGQITAILDQKNYVEELNRHL-----------NATVNNLQAKVDALEKS
NTKLTEELAVANN-RIITLQEEMERVKEESSYILESNR-----------------KGPKQDRTSEGQALS----------
-------EARKHLKEETQLRLDVEKELEIQIGMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLRALKHELAFKLQ---
-----------SSDLGVKQKSELNSRLEEKTNQMAATIKQLEQRLRQAERGRQSAELDNRLFKQDFGDKINSLQLEVEEL
T--------------RQRNQLELELKQERE------------------------RRLQNNSN-VPGKGSQK-TEPKTDGK
HRIQEEN------------VNLKKPLEESHRLQSHP-MDQQ-DQPLLSEKP--------QVCQL----------------
-----------CQEDD--GSIKKNVCKNCKGTFCNACSTNELPLPSSITPERVCNSCHKHLMKQYSTSP-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Dasypus_novemcinctus_RUFY3
--------------------------------------------------------------------------------
MSALTPP----------------------------------TDMPTPTTDKITQ------------AAMETIYLCKFRVS
MDG-------EWLCLRELDDISLTPDPEP-----------------THED------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------PN
YLMANERMNLMNMAK-----------------LSIKGL------IESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLK--
--------------------AKKTFLG-QNKSFWGPLE-VEKLV------------------------------------
------------------PEAAEITASVKDLPG-LKTPVGRG--------------------------------------
------------------------------RAWLRLALMQKKLSEYMKALINKKELL---------------------SE
FYEPNALMMEEEGAIIAG---------------------------------------------------------LLVGL
NVIDAN----------------------------------------------------------FCMKGEDLDSQ-VGVI
DFSMYLKDG-NSSKGSE-G------------DGQITAILDQKNYVEELNRHL-----------NATVNNLQAKVDALEKS
NTKLTEELAVANN-RIITLQEEMERVKEESSYILESNR-----------------KGPKQDRTSEGQALT----------
-------EARKHLKEETQLRLDVEKELEIQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLRALKHELAFKLQ---
-----------SSDLGVKQKSELNSRLEEKTNQMAATIKQLEQRLHQAERGRQSAELDNRLFKQDFGDKINSLQLEVEEL
T--------------RQRHRLELELKQERE------------------------SRLQNNRSSIPGKGMQK-PEPKMVEK
QKIQEEN------------VKLKTPFEEIYRLQSHS-LDEQ-DQPPDSEKT--------DKLTL----------------
-----------LNKKMF-LSVTENVCKNCRGTFCNACSANELPLPSSIKPERVCNPCHQHLIKQYSTSPS----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Gallus_gallus_RUFY3
--------------------------------------------------------------------------------
-------------------------------------------MPTPTTDKITQ------------AAMETIYLCKFRVS
MDG-------EWLCLRELDDISLTPDPEP-----------------THED------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------PN
YLMANERMNLMNMAK-----------------LSIKGL------IESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLK--
--------------------AKKTFLG-QNKSFWGPLELVEKLV------------------------------------
------------------PEAAEITASVKDLPG-LKTPVGRG--------------------------------------
------------------------------RAWLRLALMQKKLSEYMKALINRKDLL---------------------SE
FYEPNALMMEEEGAIIAG---------------------------------------------------------LLVGL
NVIDAN----------------------------------------------------------FCMKGEDLDSQ-VGVI
DFSMYLKDG-NSTKGSE-G------------DGQITAILDQKNYVEELNRHL-----------SATVNNLQAKVDALEKS
NTKLTEELAVANN-RIITLQEEMERVKEESSYILESNRK-----------------VTK-DRTADGQALT----------
-------EARKQLKEETQLRLDVEKELEAQIGMRQEMELAMKMLEKDVCEKQDALVALRQQLDDLRALKHELSFKLQ---
-----------SSDMGVKQKSELNSRLEEKTNQMAATIKQLEQRLRQAEKDRQLAQQDNRLFKQEFGDKINSLQLEVEEL
S--------------RQRSHLELELKRERERWS------------------HSHQSSQGNK------KGP-KNWLKPDGK
LRIQDENA-----------KLKQAPREENSVLPHKLQSSTQEEQEQPSGPGNAQICQL----------------------
------------CQEESSRSKKKNICKNCGGIFCEACSANELPLPSSINPERVCNPCHKQLIQQYSTSPL----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Xenopus_tropicalis_RUFY3
--------------------------------------------------------------------------------
MSALTPP----------------------------------SDMPTPTTDKITQ------------AAMETIYLCKFRVS
MDG-------EWLCLRELDDISLTPDPEP-----------------NPED------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------PN
YLMANERMNLMNMAK-----------------LSIKGL------IESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLK--
--------------------AKKTFLG-QNKSFWGPLELVEKLV------------------------------------
------------------PEAAEITASVKDLPG-LRTPVGRG--------------------------------------
------------------------------RAWLRLALMQKKLSEYMKALINRKDLL---------------------SE
FYEPNALMMEEEGAIISG---------------------------------------------------------LLVGL
NVIDAN----------------------------------------------------------FCMKGEDLDSQ-VGVI
DFSMYLKEG-PIAKCSE-G------------DGQITAILDQKNYVEELNRQL-----------SATVNNLQAKVDALEKS
NTKLTEELAVANN-RIITMQEEMERIKEETSYYSEASKK-----------------VNKQERTADGQALS----------
-------EVKKHLKEETQLRLDIEKELEVQIGMRQEMELAMKMLDKDVCEKQDALAALRQQLDDLRALKHELSFKLQ---
-----------SSDLALKQKSELNSRLEEKTNQMAATVKQLEQ----SEKD---------LVKQAK-----TLNSVAHKL
L--------------QKQH-------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Danio_rerio_RUFY3a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------DP---------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------------K
DPIAIERLNLMNMAK-----------------LSIKGL------IESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLK--
--------------------SKKTFLG-QNKSFWGPLELVEKLT------------------------------------
------------------PEAGEITASVKDLPG-LKTPLGRG--------------------------------------
------------------------------RAWLRLALMQKKLSDYMKTIINRKDLL---------------------GE
FYEPNALMMEEEGAVIAG---------------------------------------------------------LLVGL
NVIDAN----------------------------------------------------------LCMKGEDLDSQ-VGVI
DFSMYLKDGAHSSKSTE-G------------DGQITAILDQKNYVEELNRHL-----------SASVNNLQAKVDALEKS
NTKLTEELAVANN-RIITLQEELERVKEEGSYFVESSRK-----------------ASRADGTANGQVLG----------
-------ETRKQLKEETQLRLDVEKELELQIGMKQEMELSMKMLEKDICEKHDALVELRQQLDDVRTLNHELSVKSQ---
-----------SSESSAKQKSDIIGRLEEKTNQMGSIIKQLESRCKKAERERDLADEANRLFKQEFGDKIESLQTEVEQL
R--------------RQRWILEQELKKGRD---------------------------HPG-VQTPETLLGKTPPQQRDSK
QHIEDIRK-----------ENDTLRTALEEKTSLSSSLTLSHEDE-----------QNQSLCKEVD--------------
------PSICTMCENQDSLTSPKSQCKNCSGVFCENCMANELPLPSSINPEHVCDVCYSQLLEQYSSSPS----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Takifugu_rubripes_RUFY3a
--------------------------------------------------------------------------------
-------------------------------------------------RAGDH------------LSLQLSRVRGRRVA
LPAR---------AQRHLPHPGPRAGPHP---------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------------K
DPIAIERLNLMNMAK-----------------LSIKGL------IESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLK--
--------------------TKKTFLG-QNKSFWGALELVEKLT------------------------------------
------------------PEAGEITASVKDLPG-LKTPLGRG--------------------------------------
------------------------------RAWLRLALMQKKLSDYMKTIINRKDLL---------------------SE
FYEPNALMMEEEGAVIAG---------------------------------------------------------LLVGL
NVIDAN----------------------------------------------------------LCMKGEDLDSQ-VGVI
DFSMYLKDGGHSSKSAE-G------------DGQITAILDQKNYVEELNRHL-----------SASVNNLQAKVDALEKS
NTKLTEELAVANN-RIITLQEDVERVKEESSYQLESRKKRVEAFLCYFIII--FLQAVRSDSASDGQALG----------
-------ETRKQLKEETLLRLDVEKELEVQIGMKQEMEMSMKMLEKDVCEKQDALVELRQQLEDLRAINQQLLHKTQ---
-----------SSDAGSKQKSETISRLDEKINQMTGTVKQMEARCKQAERERDLALEANRLFKQDFGDKIESLQEEVEQL
K--------------KHRFYLERQLKKERE---------------------------QRS--ASRQVVIPQKEPRPTESS
PKVSSNERKLLLWSRFSVTEYISPTVDSRRPVGQKGEQPVNHRSRGQIQS----QLQPESFVNISQ--------------
------PSICSMCEEDESLLKTKKQCKNCSGVFCDSCVRNELPLPSSILPEIVCNGCFSLLLQQYASTPT----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Tetraodon_nigroviridis_RUFY3a
--------------------------------------------------------------------------------
MSDLTPQ----------------------------------GETPTPTTDKITQ------------AARETIYLCNFRVS
VDG-------EWLCLRELNDISLTPDPEP-----------------AHE-------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------------------DPK
DPIAIERLNLMNMAK-----------------LSIKGL------IESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLK--
--------------------TKKTFLG-QNKSFWGALELVEKLT------------------------------------
------------------PEAGEITASVKDLPG-LKTPLGRG--------------------------------------
------------------------------RAWLRLALMQKKLSDYMKTIINRKDLL---------------------SE
FYEPNALMMEEEGAVIAG---------------------------------------------------------LLVGL
NVIDAN----------------------------------------------------------LCMKGEDLDSQ-VGVI
DFSMYLKDGGHSSKSAE-G------------DGQITAILDQKNYVEELNRHL-----------SASVNNLQAKVDALEKS
NTKLTEELAVANN-RIITLQEDVERVKEESSYQLESRKA------------------VRSDSASDGQALG----------
-------ETRKQLKEETLLRLDVEKELEVQIGMKQEMEMSMKMLEKDICEKQDALVELRQQLEDLRAINQQLLHKSQ---
-----------TSDASSKQKNEAISRLEEKINQMSGTVKQMEA----SEKH---------LVKQAR-----NLNSAAGKL
L--------------QFQQ-------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Gasterosteus_aculeatus_RUFY3a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------MNMGQ-----------------LSIKGL------IESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLK--
--------------------TKKTFLG-QNKSFWGALELVEKLT------------------------------------
------------------PEAGEITASVKDLPG-LRTPLGRG--------------------------------------
------------------------------RAWLRLALMQKKLSDYMKTIINRKDLL---------------------SE
FYEANALMMEEEGAVIAG---------------------------------------------------------LLVGL
NVIDAN----------------------------------------------------------LCMKGEDLDSQ-VGVI
DFSMYLKDGGHSSKSAE-G------------DGQITAILDQKNYVEELNRHL-----------SASVNNLQAKVDALEKS
NTKLTEELAVANN-RIITLQEDVERVQEESSYQLETRKVSASSSLG---------SASRSESAPDGQVLG----------
-------ETRKQLKEETLLRLDVEKELEVQIGMKQEMELSMKMLEKDVCEKQDALVELRQQLEDLRVINQQLSHKSQ---
-----------SADAGSKQKSEAIARLEEKINQMSGTVKQMETRCKQAERERVLALEANRLFKQEFGDKIESLQVEVEQL
R--------------KHRSHLELELRKERH---------------------------RHGDGSSSQSGVPRRETRLPEDI
ANIPKVQLRVTTRPSIYIGQKGERAVQHGNRGQNQSELQLCLISEASTNPSLVYYVQDEEEEEVCQ--------------
------PSICSMCERDDSLTKTKRRCKNCEGVFCEGCVSNELPLASSILPETVCTACYSLLLQQYASTPT----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Oryzias_latipes_RUFY3a
--------------------------------------------------------------------------------
MSDLTPQ----------------------------------SETPTPTTDKITQ------------AARETIYLCNFRVS
VDG-------EWLCLRELNDISLTPDPEP-----------------AHEEKWDSFKKSEDV-------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------SPDPK
DPVAIERLNLMNMAK-----------------LSIKGL------IESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLK--
--------------------TKKTFLG-QNKSFWGALELVEKLT------------------------------------
------------------PEAGEITASVKDLPG-LRTPLGRG--------------------------------------
------------------------------RAWLRLALMQKKLSDYMKTIINRKDLL---------------------SE
FYEPNALMMEEEGAVIAG---------------------------------------------------------LLVGL
NVIDAN----------------------------------------------------------LCMKGEDLDSQ-VGVI
DFSMYLKDGGHSSKSAE-G------------DGQITAILDQKNYVEELNRHL-----------SASVNNLQAKVDALEKA
NTKLTEELAVANN-RIITLQEDVERVKEESSFQLESRKS------------------ARGDPAADGSALT----------
-------ETRKQLKEETLLRLDVERELEVQIGMKQEMEMSMKMLEKDVCEKQDALMELRQQLDDLRTINQQLSHKSQ---
-----------SADSSSKQKGEVIARLEDKISQMSGTVKQLES----SDKH---------LVKQAR-----NLSTSAGKL
L--------------QLKP-------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Ciona_savignyi_RUFY3
--------------------------------------------------------------------------------
----------------------------------------------------GK------------KSMK----------
VE------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------RRSLLGMAK-----------------LSVKGL------IESSLSAGHTLDSDHTPLQQFFVIIEYVLRQGLK--
--------------------APKNFFM-PNKYFWPPLEAIERLN------------------------------------
------------------SEASEITSSVRSLPG-IRTHLGKG--------------------------------------
------------------------------RAWLRLAIMQKKLADYFKILIDNKEML---------------------SE
WYDEGALLMNEEATVLAG---------------------------------------------------------HLVGL
NCIDAH----------------------------------------------------------LLHVSDSFEY--EMVI
DYSLYMKDGNHG---IFMEEENG-----DEDESAMQKLVNQKNYLEERNRHLE-----------DSSNDLQKRTDQLEAE
NKTMMQEVEALKI-QMSELKSEREKMI----------------REKDLDT---ERETLRKSKAGLDEMYT----------
-------QIQKQLKHETQMRMEVEKELELQMSMKHELEVAMKLLEKDIYDKQDGLVTLREQLDNVKAINLEIYKKLQ---
-----------SKSIVEEDKNKTILSLENETRSLAKKVSKLQQQLEEEERNTLVAR-----------EQAGRYNQQLDDM
E--------------NKRIALTTNIQVEREWRQSLEAKLE-----------------KMEQDKVLLEEQLSVMSQLREEL
RLVTIDR------------DDLRQSCMEQEHTINDLAGHLGESKQVLGDLKEVHKTMTS-SQWESDKQ------------
------ASTCAQCEKPFNLARRKHHCRNCGQIYCNSCSDNTMPLASSAKPVRVCDTCHTTL-------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Branchiostoma_floridae_RUFY3
--------------------------------------------------------------------------------
-------------------------------------MAEETIYLCNFRVSVDG------------EWLCLRELGDLSVT
PQ--------------LESPQEVPEEND----------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------------------PPK
DPTAIERANLLNMVK-----------------LSIKSL------IESSYQVGRTLDKDFAPLQQFLIVMEHVLKHGLK--
--------------------GVSHGLH-SNK---LTVSSGPSAA------------------------------------
------------------PSKVQIHVPDSDVGT-LLTYPGKA--------------------------------------
------------------------------RAWLRLAMMQKRLADYVKTLVEKK-DV--------------------MGE
FYEPFALLMEEEGMVLAG---------------------------------------------------------LLVGL
NVIDCN----------------------------------------------------------FCVKEDDFDSQ-LGVI
DFSMYLKDPGNYTDRSPGE---------ASRKIFLTYILQ---LLENYRYHLSL----------ATVTNLQARIENLEKD
NSNLSEKLAMANN-RVLQLQEEGDKLQTENTRIKGDLE---------------KKLVKSR--AGLDDMYV----------
-------EAQKQLRDETQMRLDVEKELELQISMKQEMEMAMKLLEKDIHEKQDMIVGLRKQLDDIKAINIDMYKKFQ---
-----------AAEGSLKHKTEMLVKLEEKCTQMSQTIKDIEQR------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----SVLLICVSVNCNEAV-------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Homo_sapiens_RUFY1
------------------------------MADREGGCAAGRGRELEPELEPGPGPGSAL---------------EPGEE
FEIVDRSQLPGPGDLRSATRPRA-------------AEGWSAPILTLARRATGN------------LSASCGSALRAAAG
LG------GGDSG-DGTAR----AASKCQ---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MMEERANLMHMMK-----------------LSIKVL------LQSALSLGRSLDADHAPLQQFFVVMEHCLKHGLK--
--------------------VKKSFIG-QNKSFFGPLELVEKLC------------------------------------
------------------PEASDIATSVRNLPE-LKTAVGRG--------------------------------------
------------------------------RAWLYLALMQKKLADYLKVLIDNKHLL---------------------SE
FYEPEALMMEEEGMVIVG---------------------------------------------------------LLVGL
NVLDAN----------------------------------------------------------LCLKGEDLDSQ-VGVI
DFSLYLKDVQDLDGGKE--------------HERITDVLDQKNYVEELNRHL-----------SCTVGDLQTKIDGLEKT
NSKLQEELSAATD-RICSLQEEQQQLREQNELIRERSEKSVEITKQDTKV---ELETYKQTRQGLDEMYS----------
-------DVWKQLKEEKKVRLELEKELELQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKAQ---
-----------NAESSLQQKNEAITSFEGKTNQVMSSMKQMEERLQHSERARQGAEERSHKLQQELGGRIGALQLQLSQL
H--------------EQCSSLEKELKSEKEQRQALQRELQ---------------HEKDTSSLLRM--ELQQVEGLKKEL
RELQDEK------------AELQKICEEQEQALQEMGLHLSQSKLKMEDIKEVNQALKG-HAWLKDDE------------
------ATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVCDSCHTLLLQRCSSTAS----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Pongo_abelii_RUFY1
------------------------------MADREGGWAAGRERELEPEPEPGPGPGSAL---------------EPGEE
FEIVDRSQLPGPGDLRSATRPRA-------------AEGWSAPILTLARRATGN------------LSASCGSALRAAAG
LG------GGDSG-DGTAR----AASKCQ---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MMEERANLMHMMK-----------------LSIKVL------LQSALSLGRSLDADYAPLQQFFVVMEHCLKHGLK--
--------------------VKKSFIG-QNKSFFGPLELVEKLC------------------------------------
------------------PEASDIATSVRNLPE-LKTAVGRG--------------------------------------
------------------------------RAWLYLALMQKKLADYLKVLIDNKHLL---------------------SE
FYEPEALMMEEEGMVIVG---------------------------------------------------------LLVGL
NVLDAN----------------------------------------------------------LCLKGEDLDSQ-VGVI
DFSLYLKDVQDLDGGKE--------------HERITDVLDQKNYVEELNRHL-----------SCTVGDLQTKIDGLEKT
NSKLQEELSAATD-RICSLQEEQQQLREQNELIRERSEKSVEITKQDTKV---ELETYKQTRQGLDEMYS----------
-------DVWKQLKEEKKVRLELEKELELQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKAQ---
-----------NAESSLQQKNEAITSFEGKTNQVMSSMKQMEERLQHSERARQGAEERSHKLQQELGGRIGALQLQLSQL
H--------------EQCSSLEKELKSEKEQRQALQRELQ---------------HEKDTSCLLRT--ELQQVEGLKKEL
RELQDEK------------AELQKICEEQEQALQEMGLHLSQSKLKMEDIKEVNQALKG-HTWLKDDE------------
------ATHCRQCEKEFSISRRKVRGSSTHPPSALSHCPLRFPLSLVPEAHIRPGSLPVTVLTGWQMGSPASPVCLCRWL
SILAPSF-------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Mus_musculus_RUFY1
------------------------------MAARGECRRAGQDSEPEPEREPESEPGPEPEPQAG---------LESGEA
FEIVDRSQLPSPGELRSASRPRV-------------ADSWSAPILTLARRATGN------------LSASCGSALRAAAG
LG--------DGGGGG-ER----AASKGQ---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MMEERANLMHMMK-----------------LSIKVL------LQSALSLGRSLDADYAPLQQFFVVMEHCLKHGLK--
--------------------VKKSFIG-QNKSFFGPLELVEKLC------------------------------------
------------------PEASDIATSVRNLPE-LKTAVGRG--------------------------------------
------------------------------RAWLYLALMQKKLADYLKVLIDNKQLL---------------------SE
FYEPEALMMEEEGMVIVG---------------------------------------------------------LLVGL
NVLDAN----------------------------------------------------------LCLKGEDLDSQ-VGVI
DFSLCLKDAQDLDSGRE--------------HERITDVLDQKNYVEELNRHL-----------SCTVGDLQTKIDGLEKT
NSKLQEELSAATD-RICSLQKEQQQLREQNEVIRERSEKSVEITKQDTKV---ELETYKQTRQGLDEMYS----------
-------DVWKQLKEEKKVRLELEKELELQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKVQ---
-----------SAESSLQQKNEAIASFEGKTTQVMSSMKQMEERLQQAERARQAAEERSHKLQQELSGRGSALQLQLSQL
R--------------DQCSGLEKELKSEKEQRQALQRELQ---------------REKDTSCLLQT--ELQQVEGLKKEL
RELQDEK------------AELRKVCEEQEQALQEMGLHLSQSKLKMEDIKEVNKALKG-HTWLKDDE------------
------ATHCKQCEKDFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVCDSCHTLLLQRCSSTAS----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Rattus_norvegicus_RUFY1
------------------------------MAARGDCRRAGQDSEPEPKPEPESR--PEPGLQAG---------LESGEE
FEIVDRSQLPSPGELRSASRTRA-------------AESWSAPILTLARRATGN------------LSASCGSALRAAAG
LG--------DGGGGGGER----AASKGQ---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MMEERANLMHMMK-----------------LSIKVL------LQSALSLGRSLDADHAPLQQFFVVMEHCLKHGLK--
--------------------VKKSFIG-QNKSFFGPLELVEKLC------------------------------------
------------------PEASDIATSVRNLPE-LKTAVGRG--------------------------------------
------------------------------RAWLYLALMQKKLADYLKVLIDNKHLL---------------------SE
FYEPEALMMEEEGMVIVG---------------------------------------------------------LLVGL
NVLDAN----------------------------------------------------------LCLKGEDLDSQ-VGVI
DFSLYLKDVQDLDSGRE--------------HERITDVLDQKNYVEELNRHL-----------SCTVGDLQTKIDGLEKT
NSKLQEELSAATD-RICSLQEEQQQLREQNELIRERSEKSVEITKQDTKV---ELETYKQTRQGLDEMYS----------
-------DVWKQLKEEKKVRLELEKELELQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKVQ---
-----------SAESSLQQKDEAIASFEGKTTQVMSSMKQMEERLQQAERARQGAEERSYKLQQELSGRVSALQLQLSQL
R--------------DQCSGLEKELKSEKEQRQTLQRELQ---------------HEKDTSCLLQT--ELQQVEGLKKEL
RELQDEK------------AELRKVCEEQEQALQEMGLHLSQSKLKMEDIKEVNKALKG-HTWLKDDE------------
------ATHCKQCEKDFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVCDSCHTLLLQRCSSTAS----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Felis_catus_RUFY1
------------------------------MADGESGCPAGR----EPEQAPGP---------------------EPGEE
FEIVDRSQLPSPSELRSAAKPRVG------------PEGWSAPILTLARKATGN------------LSASCGSALRAAAG
LG------GADGGADGAAR----AASKCQ---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MMEERANLMHMMK-----------------LSVKVL------LQSALSLGRSLDADHAPLQQFFVVMEHCLKHGLK--
--------------------VKKSFIG-QNKSFFGPLELVEKLC------------------------------------
------------------PEASDIATSVRNLPE-LKTAVGRG--------------------------------------
------------------------------RAWLYLALMQKKLADYLKVLIDNKHLL---------------------SE
FYEPEALMMEEEGMVIVG---------------------------------------------------------LLVGL
NVLDAN----------------------------------------------------------LCLKGEDLDSQ-VGVI
DFSLYLKDVQGLDGGKE--------------HERITDVLDQKNYVEELNRHL-----------SCTVGDLQNKIDGLEKT
NSKLQEELSAATD-RICSLQEEQQQLREQNELIRERSEKSVEITKQDTKV---ELDTYKQTRQGLDEMYS----------
-------DVWKQLKEEKKVRLELEKELELQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKVQ---
-----------NAESCLQQKNEAITSFEEKTNQVMSSMKQMEERLRQSERARQGAEERSHRLQQELGGRTCALQQQLSQL
H--------------EQCSSLEKELKSEKEQRQALQRELQ---------------QEKDTSSLLPI--LEKQAAVIAKEL
RELQDEK------------AELQKVCEEQEQALQEMGLHLSQSKLKMEDIKEVNKALKG-HTWLKDDE------------
------ATHCKQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVCDSCHTLLLQRCSSSTG----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Loxodonta_africana_RUFY1
---------------------------------------PER--------GPEPGP-------------------ESGEE
FEIVDRNQLPSPGELKSAAQPRAA------------ADGWSAPILTLARKATVN------------LSASCGSALRAAAG
RG------VGDGIGDGAAR----AAAKCQ---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MMEERANLMHMMK-----------------LSIKVL------LQSALSLGRSLDADHAPLQQFFVVMEHCLKHGLK--
--------------------VKKSFIG-QNKSFFGPLELVEKFC------------------------------------
------------------PEASDIATSVKNLPE-LKTAVGRG--------------------------------------
------------------------------RAWLYLALMQKKLADYLKVLIDNKHLL---------------------SE
FYEPEALMMEEEGTVIVG---------------------------------------------------------LLVGL
NVLDAN----------------------------------------------------------LCLKGEDLDSQ-VGVI
DFSLYLKDVQDLDGGKE--------------HERITDVLDQKNYVEELNRHL-----------SCTVGDLQAKIDGLEKT
NSKLQEELSAAAG-RICSLQEEQHQLREQNELIRERSEKSVEITKQDTKV---ELETYKQTRQGLDEMYS----------
-------DVWKQLKEEKRVRSELEKELELQIAMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKVQ---
-----------NAESNLQQKNEAITSFEGKTTQVMSSMKQMEERLQHSEQARQGAEERSHKLQQELGGRVSALQQQLAQL
H--------------MQCSSLEKELKSEKEQRQALQRELQ---------------HEKDTSSLLRT--ELQQVEGLKKEL
RELQDEK------------AELQKVCNEQEQALQEMGLHLSQSKLKMEDIKEVNKALKG-HTWLKDDE------------
------ATHCKQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVCDSCHTLLLQRCSSTAS----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Dasypus_novemcinctus_RUFY1
------------------------------MADGEDGGPAGR--------GPGPGP-------------------DPGEE
FEIVDRSQLPGPGELRGSARPRAA------------AESWSAPILTLARRATGN------------LSASCGSALRAAAG
---------LDGGADGAAR----AASKSQ---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MMEERVNLMHMMK-----------------LSIKVL------LQSALSLGRSLDADHAPLQQFFVVMEHCLKHELK--
--------------------VKKSFIG-QNKSFFGPLELVEKLC------------------------------------
------------------PEASDIATSVKNLPE-LKTAVGRG--------------------------------------
------------------------------RAWLYLALMQKKLADYLKVLTDNKHLL---------------------SE
FYEPEALMMEEEGMVIVG---------------------------------------------------------LLVGL
NVLDAN----------------------------------------------------------LCLKGEDLDSQ-VGVI
DFSLYLRDVQDLNGGKE--------------HERITDVLDQKNYVEELNRHL-----------SCTVGDLQAKVDGLEKT
NSKLQEELSAATD-RICSLQQEQQQLREQNDLIRERSEKSVEITKQDTKV---ELETYKQTRQGLDEMYS----------
-------DVWKQLKEEKRVRLELEKELELQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEDVKAINLQMFHKVQ---
-----------SAESNLQQKNEAILSFEGKTNQAMSSMKQMEERLQHSERARQGAEERSRKLQQELGGRVGALQQQLSQL
H--------------DQCSSLEKELKSEKEHRQALQRELQ---------------HEKDTSSLLRT--ELQQVEGLKKEL
RELQDEK------------TDLQKVCDEQEQALQEMGLHLSQSKLKMEDIKEVNKALKG-HAWLKDDE------------
------ATHCKQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVCDSCHTLLLQRCSSTTS----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Ornithorhynchus_anatinus_RUFY1
------------------------------MAEEEAGVAPGP---------------------------------GSGPD
SELGGGGGGEGEGEGEGCLAPRPAERSREEKEKAPEEAGWSAPILSLAKKASEN------------LSAGYGNALKSAVS
VA-LVSKLPG--GGDHPAKTSRDPFPKCQ---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MMEERSNLMNMMK-----------------LSVKVL------IQSALSLGRSLDSDYPPLQQFFVVMEHCLKHGLK--
--------------------VKKSFIG-QNKSFFGPLELVEKLC------------------------------------
------------------PEASDIATSVKNLPE-LKTAVGRG--------------------------------------
------------------------------RAWLYLALMQKKLADYLKVLIDNKHLL---------------------SE
FYEPEALMVEEEGAVIVG---------------------------------------------------------LLVGL
NVLDAN----------------------------------------------------------LCLKGEDLDSQ-VGVI
DFSLYLKDGQDIGGTENSR------------HENITDVLDQKNYVEELNRRL-----------SCTVGDLQAKIDCLEKT
NAKLQEEAQCSAL-SCTSLTEEQLQLKKQNELIRERSEKSVEVTKQDTKV---ELETYKQTRQGLDELYS----------
-------DVWKQLKEEKRVRAELEKELELQIGLKTEMEIAMKLLEKDTHEKQDSLVALRQQVEEVKAINLQMFQKAQ---
-----------NAESSLQQKSEAITSYEGKTCQVMTAMKQMEERWRHSEKARQGAEEKNSKLKQEFGGQIEALRQQLSQL
D--------------KQCSSLERELKSEKEQRQTLQQELE---------------REKDTTSLLKT--ELQQVDGLKQEL
RKLQGEK------------EKLQNTCEEQEQALQEMGLHLSQSKLKMEDIKEVNKALKG-HTWLKDDE------------
------ATQCKQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVCDACHTLLLQRCSSNSS----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Gallus_gallus_RUFY1
----------------------------------------------------------------------------MKED
FEIIDKTQVPDTAELKNVE-----------KEK--EEAKWSAPILSLAKKASEN------------LALSYGSALKSAAS
VG--------LISKAVSNDSTAKTTARHH---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--AMEERANLMNMMK-----------------LSIKTL------IQSALSLGRTLDSDFPPLQQFFVVLEHCLKHGLK--
--------------------AKKTFIG-QNKSFFGPLELVEKLC------------------------------------
------------------PEASDIATSVKNLPE-LKTAVGRG--------------------------------------
------------------------------RAWLYLALMQKKLADYLKVLLDHKHLL---------------------SE
FYEPDALMMEEEGAVIVG---------------------------------------------------------LLVGL
NVIDAN----------------------------------------------------------LCLKGEDLDSQ-VGVI
DFSLYLKETQDSD-GKQ--------------DGDITAVLDQKHYVEELNRHLR-C--------SCTVTDLQNKIDCLEKT
NSKLQEELAAATD-RIGSLQEEQQQLKQQNELIRERSEKSVEVTKEDTKV---ELDTYRQSRQGLDEMYS----------
-------DVWKQLKEEKKIRLELEKELELQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKSQ---
-----------NAECSLQQKTEAISSFEG-TNEMMSAMKQMEERLQHAEKARQAAEERCNKMKQELASRLDTCRQQMSQL
D--------------SKCSTLEKELKSEKEQRQTLQRELH---------------REKDATSLLKT--ELEQMEGLKKEL
RKLQDEK------------QQLEKVCEEQEQALQEMGLHLSQSKLKMEDIKEVNKALKG-HTWLKDDE------------
------ATHCKQCEKEFSISRRKHHCRNCGDIFCNACSSNELALPSYPKPVRVCDSCHTLLLQRCSSNSS----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Taeniopygia_guttata_RUFY1
------------------------------------------------------------------------------ED
FEIIDKKQLPDAAELSNEE-----------KAKP-EEARWSAPILSLARKASEN------------LALSYGSALKSASL
VG--------LVDSPAK---TIRSRMRCH---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--TMEERANLMNMMK-----------------LSIKIL------IQSALSLGRTLDSDFPPLQQFFVVLEHCLKHGLK--
--------------------AKKTFIG-QNKSFFGPLELVEKLC------------------------------------
------------------PEASDIATSVKNLPE-LKTAVGRG--------------------------------------
------------------------------RAWLYLALMQKKLADYLKVLLDHKHLL---------------------SE
FYEPDALMMEEEGAVIVG---------------------------------------------------------LLVGL
NVIDAN----------------------------------------------------------LCLKGEDLDSQ-VGVI
DFSLYLKETQDSD-SKQ--------------DGGITAVLDQKHYVEELNRHL-----------SCTVADLQNKIDCLEKT
NSKLQEELAAATD-RIGSLQEEQQQLKQQNELIRERSEKSVEVTKEDTKV---ELDTYKQSRQGLDEMYS----------
-------DVWKQLKEEKKIRLELEKELELQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKSQ---
-----------NAECSLQQKTEAISSFEGKTNEMMSSMKQMEERLQQAEKARQAAEERCNKMKQELAGRLDSCRQQMAQL
D--------------SKCSTLEKELKSEKEQRQTLQKELH---------------QEKDATTLLKT--ELQQMEGLKKEL
RKLQDEK------------QQLKKVREEQEQALQEMGLHLSQSKLKMEDIKEVNKALKG-HTWLKDDE------------
------ATHCKQCKKEFSISRRKHHCRNCGDIFCNTCSSNELALPSYPKPVRVCDNCHTLLLQQCSNSS-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Anolis_carolinensis_RUFY1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---MEERSNLMNMIK-----------------LSIKVL------IQSALSLGRTLDSDFPPLQQFFVVMEHCLKHGLK--
--------------------AKKSFIG-QNKSFFGPLELVEKLC------------------------------------
------------------PEASDLATSVRNLPE-LKTPVGRG--------------------------------------
------------------------------RAWLYLAVMQKKLADYLKVLLDHKHLL---------------------SE
FYESDALMMEEEGAVMVG---------------------------------------------------------LLVGL
NVIDAN----------------------------------------------------------LCLKGEDLDSQ-VAVI
DFSLYLKDTQSSDNGKE--------------DGGITAVLDQKHYVEELNRHL-----------SCTVGDLQTKIESLEKT
NSKLQEELTAATD-RIRALQDEQQELRQQNEQIRERSEKHVEVTKEDTKV---ELETYKQTRQGLDEMYS----------
-------DAWKQLKEEKRIRMELEKELELQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFNKSQ---
-----------NTETTLQQKKEAISSFEGKTNQIMSSIKQMEDRLQHAEKAKRDAEEKSVKLKRELGSRIETLKQQLSQL
D--------------NKCSTLEKELKSEKEQRQTLQQELH---------------QEKDTTTLLKT--ELQQVEGLKKEL
RKLQEEK------------QQLEKTCEEQEQALQEMGLHLSQSKLKMEDIKEVNKALKG-HTWLKDDE------------
------ATHCKQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVCDTCHTLLLQRCSSNSS----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Xenopus_tropicalis_RUFY1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------H---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--KMDERANLMNRMK-----------------LSIKVL------IQSALNLGRCIDSEYPPLQQFFLVMEHCLKHGLK--
--------------------VKKTFMA-QNKSFYGPLELVEKLC------------------------------------
------------------PESSDLFANIKNLPE-LKTAIGKG--------------------------------------
------------------------------RAWLHLALMQKKLADYLQALIDHKDLLR-------------------ISD
FYEQDALMMEEEGAVIVG---------------------------------------------------------LLVGL
NMIDAN----------------------------------------------------------LCLKGEDLDSQ-VGVI
DFSFYLKDMQQNDNEKQ--------------SDEIVAVLDQKHYVEELNRHL-----------SCTVGDLQAKIDSLEKT
NSKLTKELLAAKD-RIVSLQEEHNHILQESTLIREKSERSVEVSFQDTKV---ELDTYKQSRQGLDEMYN----------
-------EIWKQLKVEKQARLELEKEFELQVGMKTEMEMAMKLMEKDIHEKQDTLVVLRKQLDDVKAINLQMCQKVL---
-----------DAETALHKKNEIVNSVQAKGDQLTSALKQIEERLQKSEKTREAAEENCNKMKMEHGAKIGSLQQQLEKL
N--------------KTCAVLEKDLKSEKEKHDTLQDKLH---------------KEKETATSLRN--ELHQFSLLQKNF
DNLHQEK------------KQLQRLCEEQEQALQEMGQHLSQSKLKMEDIKEVNKALKG-HTWLKDDE------------
------ATECKQCNKEFSISRRKHHCRNCGDIFCNSCSSNELSLPSYPKPVRVCDICHNLLLQRCSSNSS----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Danio_rerio_RUFY1a
------------------------------MADEDPNTKVESGD------------------------------VPAKEE
EPEVTETGQEDVANNTDELQKDR-----------PADSSWSAPILSFARKATET------------LSS--GVNHYSAGL
KT-------PDTTQQHSSDPVKIAAVKDP---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--VVVERSNLLSMMK-----------------LSIKVL------IQSSLSLGRTLDSEYPPLQQFFVVLEHCLKHGLK--
--------------------VRKSFIGLQNKSIWAPLEMIEKLC------------------------------------
------------------PESADIATSVRDMPG-IKTGLGRA--------------------------------------
------------------------------RAWLHLALMQKKIADYMKVLINRRDLL---------------------GE
FYEPGALVMEEEGAVIVG---------------------------------------------------------MLVGL
NVIDAN----------------------------------------------------------LCVKGEDLDSQ-VCVI
DFSMYLKDPQATESKQD--------------DSKMTAILDQKHYIEELNRHL-----------SCTVTDLQAKMDSLEKT
NSKLIEELTAATD-RINALREEQEQLKQENANILQSSQRKEEVTLQDSQV---ELETYRQTRQGLDEMYS----------
-------VVWKQYKEEKRIRQELQKELELQIGLKQEMEVAMKLLEKDTHEKQDTLVALRQQLDQVKNLNLQMFNKAQ---
-----------ASDRVAQKKEEDMVHLEKKMIQMEAAMKELEQRLQNSEDVQKNTDEQQNEIRTEMKGKVNALQKRLSDL
D--------------TLRAGLETELSAEKEQRQILQKELQ---------------REQDNSAELRT--QLQQLQGLQTEL
LDLRQEK------------QQLQQLCEEQEQALQEMGLHLSQSKLKMEDFKEVNKALKG-HAWLKDDE------------
------ATQCKQCQKEFSISRRKHHCRNCGDIYCGNCSSNELALPSYPKPVRVCDVCHSLLLQRSSTGS-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Takifugu_rubripes_RUFY1a
-------------------------AEGANMADEAEEVNTPAED------------------------------GNTGQQ
LQGTEVSEAEKNSQFCSSDRPDPGEK----PSPASTEHSWSAPLLSFARKATET------------ISS--GGAAASSPT
NS-------LPENDINYTSHQPVVPFKDH---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MSIERSNLLSMMK-----------------LSIKVL------IQSSLSLGRTLDSEYPPLQQFFVVLEHCLKHGLK--
--------------------AKKSFIG-QNKSIWGPLELVERLC------------------------------------
------------------PESANIATSARDLPG-IRTGLGRG--------------------------------------
------------------------------RAWLHLALMQKKVADYMKALLDRKDLL---------------------SE
FYEPGALMMEEEGVVMGG---------------------------------------------------------LLVGL
NVIDAN----------------------------------------------------------LCIKGEDLDSQ-VGVI
DFSLYLKDPASSETPRD--------------DSKMTAILDQKHYIEELNRHL-----------SGTVTDLQAKMDSLEKT
NSKLVEELTAATD-RINSLREEREKLQQENDSILQSSQKKEEAALQDSQV---ELETYKQTRQGLDEMYN----------
-------VVWKQYKEEKRIRQDLERELELQVGLKQEMEVAMKLLEKDTHEKQDTLAALRLQLDQVKTLNLQMFQKAQ---
-----------DSEQEAERKHAKAVQLEQRMNDMEKVIMELEQRLENSEQEHKESDQSDKDMKMELEGKVDALQKQLTDL
D--------------TLRLGLENDLRAEREQRQSLQKSLQ---------------REQDNSGELRT--QLQQLQGLHEEL
RSLKEEK------------QQLQQKCELQEQTLQEMGLHLSQSKLKMEDFKEVNKALKG-HAWLKDDE------------
------ATHCKQCQKEFSIARRKHHCRNCGDIYCSSCSSNELALPSYPRPVRVCDVCHTFLLQRSSFGSS----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Tetraodon_nigroviridis_RUFY1a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------VPSKDP---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MSIERSNLLSMMK-----------------LSIKVL------IQSSLSLGRTLDSEYPPLLQFFIVLEHCLKHGLK--
--------------------TRKSFIG-QNKSIWGPLELVEKLC------------------------------------
------------------PESANIATSARDLPG-IRTGLGRG--------------------------------------
------------------------------RAWLHLALMQKKVADYMKALLDRKDLL---------------------SD
FYEPGALMMEEEGVVMGG---------------------------------------------------------LLVGL
NVIDAN----------------------------------------------------------LCIKGEDLDSQ-VGVI
DFSLYLKDPASSEPQRD--------------DSKMTAILDQKHYIEELNRHL-----------SGTVTDLQAKMDSLEKT
NSKLVEELTAATD-RINSLREEQEKLRQENDSILQSSQKKEEVTDDDSQV---ELETYKQTRQG-DEMYN----------
-------VVWKQYKEEKHIRQDLERELELQVGLKQEMEVAMKLLEKDTHEKQDTLAALRLQLDQVKTLNLQMFKKAQ---
-----------DSEQEAERKEAKAVQLEQRMNDMEKVIVELEQRLQNSERERKQSDQSDRDMKLELEGKVDALQRQLTDL
D--------------ALRLGLENSLRVEREQRQSLQKALQ---------------REQDNSVELRT--QLQQLQGLHEEL
RSLKEEK------------QQLQQKCELQEQTLQEMGLHLSQSKLKMEDFKEVNKALKG-HAWLKDDE------------
------ATHCKQCQKEFSIARRKHHCRNCGDIYCSGCSSNELALPSYPRPVRVCDMCHALLLQRSSFGSS----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Gasterosteus_aculeatus_RUFY1a
--------------------------------------------------------------------------------
------------------AER-------------PAESGWSAPLRSLARKATET------------ISS--GVSYAAAQR
---------SLSTGSAASAPGDFVPPKDP---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MAIERSNLLSMMK-----------------LSIKVL------IQSSMSLGRTLDSEYPPLQQFFIVLEHCLKHGLK--
--------------------AKKSFIG-QNKSIWGPLELVEKLC------------------------------------
------------------PESVNIATSARDLPG-IKTGLGRG--------------------------------------
------------------------------RAWLHLALMQKTVADYMKALLDRKDLL---------------------SE
FYDSGALMVEEEGAVMGG---------------------------------------------------------LLVGL
NVIDAN----------------------------------------------------------LCIKGEDLDTQ-VGVI
DFSLYLKDPAKSETPKD--------------DTKMTAILDQKHYIEELNRHL-----------SGTVTDLQAKMDSIEKT
NSKLVEELTAATD-RINSLREEQEQLRKANETILQCTQKKEEAALQDSQV---ELETYKQTRQGLDEMYN----------
-------VVWKQYKEEKRIRQELEHELELQVGLKQEIETAMRLLEKDTHEKQDTLEALRLQLDQVKTLNLQMFHKAQ---
-----------ASDRVAERKQTEAAQLEGKMDEMERAMMDLEQRLQHSEQQRKHSDQSDEDMREELEGKVEALQKQLTDL
D--------------TQRLGLETELRTEREHRQSLQKALQ---------------QEQDNSTELRT--QLQQLQGLQAEV
QDLKHEK------------RQLQQTCGQQEQALQEMGLHLSQSKLKMEDFKEVNKALKG-HAWLKDDE------------
------ATQCKQCEKEFSIARRKHHCRNCGDIYCNSCSSNELALPSYPRPVRVCDACHALLLQRSSSTGC----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Oryzias_latipes_RUFY1a
-----------------TGTTARCRSRSRDEVLGQVQSRDEPEM------------------------------SQRQDP
QPGVGEEDSEAFEELSDRAEQDAAGK----SPSVAAENSWSAPIFSLARKASET------------ISH--GMSYAAAPR
---------KLSHGSSASS---FLPPKDP---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MGIERSNLLSMMK-----------------LSIKVL------IQSSLSLGRTLDSEYPPLQQFFVVLEQCLKHGLK--
--------------------TKKSFIG-QNKSIWGPLELVEKLC------------------------------------
------------------PESANIATSARDLPG-IRTGLGRG--------------------------------------
------------------------------RAWLHLALMQKKIADYIKALLDHKDLL---------------------SE
FYDSGAMMLEEEGSVLGG---------------------------------------------------------LLVGL
NVIDAN----------------------------------------------------------LCIKGEDLDSQ-VGVI
DFSLYLKDPASSETPKD--------------DANMTAILDQKHYIEELNRHL-----------SGTVTDLQAKLDSIEKT
NSKLVEELTAATD-RINSLQDEQEQLKKENESILQCSQKKEEAALQDSQV---ELETYKQTRQGLDEMYN----------
-------VVWQQYKEEKRIRQELQRELELQVGLKQEMEVAMKLLEKDSHEKQDTLAALRLQLEQVKTLNLQMFHRAQ---
-----------ESERQAEKKQEEAVKLEQRMKDMEKAMEEMEQRLQNSECERKQSDQSDEDMKVELEGKVDALQTQLTDL
D--------------TLRLGLENELRTEREQRQSLQKALQ---------------REQDNSSELRT--QLQQLQGLHVEL
QELKQEK------------QQLQERCEQQEQALQEMGLHLSQSKLKMEDFKEVNKALKG-HAWLKDDE------------
------ATQCKQCQKEFSIARRKHHCRNCGDIYCNSCSSNELALPSYPRPVRVCDVCHALLLQRSSSTAS----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Strongylocentrotus_purpuratus_RUFY1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------DSVIK
NPVLVERANLLNVAK-----------------LCIKTL------IESAMEEARILDDEYVPLQQFFVVLEHVMNHGVK--
--------------------GKKTFLE-KKRSFWGAVESLEKSL------------------------------------
------------------PDFAEIIDSVRNLPG-IKTSIGRG--------------------------------------
------------------------------RAWLRLAMMQKKLADYFKAIIESK-HL--------------------LSE
WYEPTALVMEEESMVIAG---------------------------------------------------------LLVGL
NAIDCN----------------------------------------------------------FCLKGDDLDSA-PSVI
DFSMYFKDELNVXTNKVID-----------RNVVLSALLDQKNYLEEHNRHLT-----------SQITGLHTRIKALEEA
NASMKGEHAMANN-NILSIQAENDLLRAENNTLKQHTD---------------RKLEMVKADIETERETYN-----TSRQ
GLNEMYSEAKQRLQQETQMRLDVEQELQLQISLKMEMEMAMRLLEKDIHEKQDTIISLRKQLEDIKSMNIDLYKKIQ---
-----------GTEETMKHKSVLVGKLEEKTNQMVDTIKQLEERLRSVEREKQA-----------CAETARKLGMQIAER
D--------------IKCSNMAADLKVEGEWRATLQKEIA-----------------QEKELISQLQAEVADVRSLREQL
ATLLGKH------------EELGKTCHEQELALTEMGSKLSDSQLKMDSMKELVQSAEGR-------------------V
WADDRDAKNCLTCDKPFSVARRKHHCRNCGGIYCGPCSDNLMPLPSSAKPVRVCDHCNTELLQRYSATSR----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Homo_sapiens_RUFY2
--------------------------------------------------------------------------------
--------------------------------------------------------------------MTFQVWGWRRED
ASQVLAWVPDAEGGRRGMLTRRSLATKDP---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--TAVERANLLNMAK-----------------LSIKGL------IESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLK--
--------------------VRKSFLS-YNKTIWGPLELVEKLY------------------------------------
------------------PEAEEIGASVRDLPG-LKTPLGRA--------------------------------------
------------------------------RAWLRLALMQKKMADYLRCLIIQRDLL---------------------SE
FYEYHALMMEEEGAVIVG---------------------------------------------------------LLVGL
NVIDAN----------------------------------------------------------LCVKGEDLDSQ-VGVI
DFSMYLKNE-EDIGNKE-R------------NVQIAAILDQKNYVEELNRQL-----------NSTVSSLHSRVDSLEKS
NTKLIEELAIAKN-NIIKLQEENHQLRSENKLILMKTQQHLEVTKVDVET---ELQTYKHSRQGLDEMYN----------
-------EARRQLRDESQLRQDVENELAVQVSMKHEIELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIEMYQKLQ---
-----------GSEDGLKEKNEIIARLEEKTNKITAAMRQLEQRLQQAEKAQMEAEDEDEKYLQECLSKSDSLQKQISQK
E--------------KQLVQLETDLKIEKEWRQTLQEDLQ---------------KEKDALSHLRN--ETQQIISLKKEF
LNLQDEN------------QQLKKIYHEQEQALQELGNKLSESKLKIEDIKEANKALQG-LVWLKDKE------------
------ATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPSSPKPVRVCDSCHALLIQRCSSNLP----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Callithrix_jacchus_RUFY2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------ATKDP---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--TAVERANLLNMAK-----------------LSIKGL------IESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLK--
--------------------VRKSFLS-YNKTIWGPLELVEKLY------------------------------------
------------------PEAEEIGASVRDLPG-LKTPLGRA--------------------------------------
------------------------------RAWLRLALMQKKMADYLRCLIIQRDLL---------------------SE
FYEYHALMMEEEGAVIVG---------------------------------------------------------LLVGL
NVIDAN----------------------------------------------------------LCVKGEDLDSQ-VGVI
DFSMYLKNE-EDIGNKE-R------------NVQIAAILDQKNYVEELNRQL-----------NSTVSSLHSRVDSLEKS
NTKLIEELAIAKN-NIIKLQEENHQLRSENKLILMKTQQHLEVTKVDVET---ELQTYKHSRQGLDEMYN----------
-------EARRQLRDESQLRQDVENELAVQVSMKHEIELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIEMYQKLQ---
-----------GSEDGLKEKNEIIARLEEKTNKITAAMRQLEQRLQQAEKAQMEAEDEDEKYLQECLSKSDSLQKQISQK
E--------------KQLVQLETDLKIEKEWRQTLQEDLQ---------------KEKDALSHLRN--ETQQIISLKKEF
LNLQDEN------------QQLKKIHHEQEQALQELGNKLSESKLKIEDIKEANKALQG-LVWLKDKE------------
------ATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPSSPKPVRVCDSCHALLIQRCSSNLP----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------
>Mus_musculus_RUFY2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------MATKDP---------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--TAVERANLLNMAK-----------------LSIKGL------IESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLK--
--------------------GRKSFLS-YNKTIWGPLELVEKLY------------------------------------
------------------PEAEEIGASVRDLPG-LKTPLGRA--------------------------------------
------------------------------RAWLRLALMQKKMADYLRCLIIQRELL---------------------SE
FYEYHALMMEEEGAVIVG---------------------------------------------------------LLVGL
NVIDAN----------------------------------------------------------LCVKGEDLDSQ-VGVI
DFSMYLKNE-EEIGNKE-R------------NVQIAAILDQKNYVEELNRQL-----------NSTVSSLHSRVDSLEKS
NTKLIEELAIAKN-NIIKLQEENHQLRSENELILMRTRQHLEVTKVDVET---ELQTYKHSRQGLDEMYN----------
-------DARRQLRDESQLRQDVENELSVQVGMKHEMELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIEMYQRLQ---
-----------GSEDGLKEKNEIIARLEEKTNKITTAMRQLEQRLQQAEKAQKEAEAEDEKYAQECLSQSDSLQRQISQK
E--------------QQLVQLETDLKIEKEWRQTLQEDLQ---------------KEKDVLSHLRH--ETQKVISLKKEF
LNLQDEN------------QQLKRIYQEQEQALQELGSKLCESKLKIDDIKEANKALQG-LVWLKDKD----------