>Homo_sapiens_RBM46
--------------------------------------------------------------------------------
--------------------------------------------------MNEENIDGTNG-------------------
-----------CSKVRTG-----------------------------IQNEAALLALMEKTGYNMVQENGQRKFGGPPPG
W---EGPPPPRGC-----EVFVGKIPRDMY-EDELVPVFERAGKIYEFRLMMEFSG-ENRGYAFVMYTTKEEAQLAIRIL
--------------------------------------NNYEIR-PGKFIGVCVSLDNCRLFIGAIPKEKKKEEILDEMK
KVT----EGVVDVIVYPSATDKTK-NRGFAFVEYESHRAAAMARRKLIP-GTFQLWGHT-IQVDWADPEKEVDEETMQRV
-------------KVLYVRNLMISTT----------------------EETIKAEFNK-FKPG-----------------
--------------------AVERVKKLRDYAFVHFFNREDAVA--AMSVMNG---KCIDGA-----SIEVTLAKPVNKE
--------NTWR---QHLNGQ-----------------------------ISPN-----------SENLIVFANKEESHP
KTLGKLPTL-----PARLNGQHSP--------SPPEVERCT--------------------------------------Y
PFYPGTKLT------------------------PISMYSLKSN---HFNS-----AVMHLDYYCNKNNWAPPEYYLYSTT
SQDGKVLLVYKIVIPAIANG---------------------SQSYFMPDKLC---TTLEDAKELAAQFTLLHLD------
--------------------------------------------YNFHRSSINSLSPVSATLSS---------------G
TPSVLPYTSRPY---SYPGYPLSPT---ISLANGSHVGQRLCISNQASFF--------
>Mus_musculus_RBM46
--------------------------------------------------------------------------------
--------------------------------------------------MNEENTDGTNG-------------------
-----------CSKVRTG-----------------------------TQNEAALLALMEKTGYNMVQENGQRKFGGPPPG
W---EGPPPPRGC-----EVFVGKIPRDMY-EDELVPVFERAGKIYEFRLMMEFSG-ENRGYAFVMYTTKEEAQLAIRIL
--------------------------------------NNYEIR-PGKFIGVCVSLDNCRLFIGAIPKEKKKEEILDEMK
KVT----EGVVDVIVYPSATDKTK-NRGFAFVEYESHRAAAMARRKLIP-GTFQLWGHT-IQVDWADPEKEVDEETMQRV
-------------KVLYVRNLMISTT----------------------EETIKAEFSK-FKPG-----------------
--------------------AVERVKKLRDYAFVHFFHREDAVA--AMSVMNG---KCIDGA-----SIEVTLAKPVNKE
--------NTWR---QHLNGQ-----------------------------ISPN-----------SENLLVYANKEESHS
KSLGKPPTL-----PTRLNGQHSP--------SPPEIERCT--------------------------------------Y
PFFPGTKLT------------------------PISMYSLKSN---HFNS-----AVMHLDYYCNKNNWAPPEYYLYSTT
SQDGKVLLVYKIVIPAIANG---------------------SQSYFMPDKLC---TTLEDAKELAAQFTLLHLD------
--------------------------------------------FNFRRSSINSLSPVSTTLSS---------------G
TPSMLPYTSRPS---SYPSYPLSPT---ISLANGSHVGQRLYISNQASFF--------
>Canis_familiaris_RBM46
--------------------------------------------------------------------------------
--------------------------------------------------MNEENIDGTNG-------------------
-----------CSKVRTG-----------------------------IQNEAALLALMEKTGYNMVQENGQRKFGGPPPG
W---EGPPPPRGC-----EVFVGKIPRDMY-EDELVPVFERAGKIYEFRLMMEFSG-ENRGYAFVMYTTKEEAQLAIRIL
--------------------------------------NNYEIR-PGKFIGVCVSLDNCRLFIGAIPKEKKKEEILDEMK
KVT----EGVVDVIVYPSATDKTK-NRGFAFVEYESHRAAAMARRKLIP-GTFQLWGHT-IQVDWADPEKEVDEETMQRV
-------------KVLYVRNLMISTT----------------------EETIKAEFNK-FKPG-----------------
--------------------AVERVKKLRDYAFVHFFNREDAVA--AMSVMNG---KCIDGA-----SIEVTLAKPVNKE
--------NTWR---QHLNGQ-----------------------------ISPN-----------SENLIVFANKEESHP
KTLGKPPTL-----PARLNGQHSP--------SPPEIERCT--------------------------------------Y
PFFPGTKLT------------------------PISMYSLKSN---HFNS-----AVMHLDYYCNKNNWAPPEYYLYSTT
SQDGKVLLVYKIVIPAIANG---------------------SQSYFMPDKLC---TTLEDAKELAAQFTLLHLD------
--------------------------------------------YTFRRSSINSLSPVSATLSS---------------G
TPSVLPYTSRPY---SYPSYPLSPT---ISLTNGSHVGQRLYISNQASFF--------
>Bos_taurus_RBM46
--------------------------------------------------------------------------------
--------------------------------------------------MSEETIDGTNG-------------------
-----------CSKVRTG-----------------------------TQNEAALLALMEKTGYNMVQENGQRKFGGPPPG
W---EGPPPPRGC-----EVFVGKIPRDMY-EDELVPVFERAGKIYEFRLMMEFSG-ENRGYAFVMYTTKEEAQLAIRIL
--------------------------------------NNYEIR-PGKFIGVCVSLDNCRLFIGAIPKEKKKEEILDEMK
KVT----EGVVDVIVYPSATDKTK-NRGFAFVEYESHRAAAMARRKLIP-GTFQLWGHT-IQVDWADPEKEVDEETMQRV
-------------KVLYVRNLMISTT----------------------EETIKAEFNK-FKPG-----------------
--------------------SVERVKKLRDYAFVHFFNREDAVA--AMSVMNG---KCIDGA-----SIEVTLAKPVNKE
--------NTWR---QHLNGQ-----------------------------ISPN-----------SENLIVFANKEESHP
KILGKPPAL-----PARLNGQHSP--------SPPEIERCT--------------------------------------Y
PFFPGTKLT------------------------PISMYSLKSN---HFNS-----AVMHLDYYCNKNNWAPPEYYLYSTT
SQDGKVLLVYKIIIPAIANG---------------------SQSYFMPDKLC---TTLEDAKELAAQFTLLHLD------
--------------------------------------------YNFRRSSINSLSPVSATLSS---------------G
TPSVLPYTSRPY---SYSSYSLSPT---IPLANGSHVGQRLYISNQASFF--------
>Equus_caballus_RBM46
--------------------------------------------------------------------------------
--------------------------------------------------MNEESIDGTNG-------------------
-----------CNKVRTG-----------------------------TQNEAALLALMEKTGYNMVQENGQRKFGGPPPG
W---EGPPPPRGC-----EVFVGKIPRDMY-EDELVPVFERAGKIYEFRLMMEFSG-ENRGYAFVMYTTKEEAQLAIRIL
--------------------------------------NNYEIR-PGRFIGVCVSLDNCRLFIGAIPKEKKKEEILDEMK
KVT----EGVVDVIVYPSATDKTK-NRGFAFVEYESHRAAAMARRKLIP-GTFQLWGHT-IQVDWADPEKEVDEETMQRV
-------------KVLYVRNLMISTT----------------------EETIKAEFNK-FKPG-----------------
--------------------AVERVKKLRDYAFVHFFNREDAVA--AMSVMNG---KCIDGA-----SIEVTLAKPVNKE
--------NTWR---QHLNGQ-----------------------------ISPN-----------SENLIVFANKEENHL
KTVGKPPTL-----PARLNGQHSP--------SPPEIERCT--------------------------------------Y
PFFPGTKLT------------------------PISMYSLKSN---HFSS-----AVMHLDYYCNKNNWPPPEYYLYS-T
SQDGKVLLVYKIVIPAIANG---------------------SQSYFMPDKLC---TTLEDAKELAAQFTLLHLD------
--------------------------------------------YNFRRSSINSLSPVSATLSS---------------G
TPSVLPYTSRPY---SYPSYSLSPA---ISLANGSHVGQRLYISNQASFF--------
>Gallus_gallus_RBM46
--------------------------------------------------------------------------------
--------------------------------------------------MNEENSAATSE-------------------
-----------SDKMRGG-----------------------------NQKAAALLALLDKTGYNMIQENGQRKFGGPPPG
W---EGPPPPRGC-----EVFVGKIPRNIY-EDELVPLFERAGKIYELRLMMEFS-------------------------
----------------------------------------------GRFIGVCISLDNCRLFIGAIPREKKKEEILKEMK
RIT----EGVVDVIVCPDATDRTK-NRGFAFVEYESHRAAAMARRRLLP-GTFQLWGRA-VQVDWACPEKEVDAETMRRV
-------------KVLYVRNLMISTT----------------------EDTIKAEFNK-FKPR-----------------
--------------------VVERVKKLRDYAFVHFYNREDAVA--AMSIMNG---KCIDGA-----SIEVTLAKPVNKE
--------STWK---QHLNGH-----------------------------VSPC-----------SENLMEFRSREDGHQ
KSVGKPASL-----SLSLNGQHSP--------SSPELEWYP--------------------------------------Y
PFLPGVKLI------------------------PISMYSLKSS---YFSS-----AVMRLDYFCYKNNWLPPEYYLYSTT
SQDGKIHLVCKVLIPSIADG---------------------SQSCFMSHKLC---TTLEDARELAARMALLHLD------
-----------------------------------------------------SCTPNSA--------------------
----------------------------------------------------------
>Xenopus_tropicalis_RBM46
--------------------------------------------------------------------------------
--------------------------------------------------MEDNCTDMFNG-------------------
-----------CSKFDFS-----------------------------IQTQVALLALIDKTGYTMVQVNGQRKFGGPPPG
W---EGPPPPRGC-----EVFVGKIPRDMY-EDELVPLFERAGKIYEFRLMMEFSG-ENRGYAFVMYTNKEEALLAIRML
--------------------------------------NNYEIR-QGKFIGVCASLDNCRLFIGSIPQEKRKEDILEEMK
KVT----EGVMDVIVCPSATDKTK-NRGFAFVTYESHRAAAMARRKLIP-GTFQLWGRT-IKVDWADPEKEVDEETMQKV
-------------KVLYVRNLMMSTT----------------------EETIKAEFNR-YKPG-----------------
--------------------VVERVKKIRDYAFVHFFRRDYAIA--AMSEMNG---RLIDGA-----RIEVTLAKPVNKE
--------AAWR---QNGNGH-----------------------------MNPN-----------SECLLNFANKE-GSQ
KVLDMCSNV-----PAYYN-QNSP--------TFLEAERCT--------------------------------------Y
PCIPGTKLT------------------------PMNLYSLKIN---HFHS-----AVMHLEYYCYKNNWSFPEYYLYATT
GQDGKMLLAYKVIVPAIAGN---------------------TNSYFMPDKLC---SIVEDAKELAAQFTLMHLD------
--------------------------------------------YSYHPTSGKNISLPSTAAAS---------------G
SSGVLPYTPKPY---SYSSYPSSPN---VSLTNGGSVGKQLYVSNQASYFSG------
>Danio_rerio_RBM46_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------MD-----------------------------SSKEAALLALMDRTGYSMVQENGQRKFGGPPPG
W---EGPPPPRGC-----EVFVGKIPRDMY-EDELVPVFEQAGHIYEFRLMMEFSG-ENRGYAFVMYTTREKAQRAIQLL
--------------------------------------DNYEIR-PGKFIGVCVSLDNCRLFIGSIPKDKKKEEIQEEMM
KVT----EGVMDVIVYPSAVDRMK-NRGFAFVEYESHKAAAMARRKLIP-GTFQLWGHT-IQVDWAEPEKELDEETMQRV
-------------RVLYVRNLMLSTT----------------------EETLRSEFSQ-LKPG-----------------
--------------------SVERVKKLTDYAFIHFYNREDALT--ALESMNG---KVIDGS-----PIEVTLAKPASK-
---DGNKRFGPR---NCHNGV-----------------------------TAAGGY---------GDSNFLFQTRNDMTI
GAMGNGLNA-----HA---LSLPY---------AVDLDRCV--------------------------------------Y
PFLPGSTLV------------------------PVSLNTVKPS---QLSS-----AVSLLDYYCHKNDWSLPEYHLYSLA
GQEGKVMLIYKVVISSTR-------------------------RSFMPDKVC---TILEDAKELAAQNALWNLD------
-------------------------------------------CSSGS----------SLNVSP---------------P
APSGSGFLSFGC---RSLPYPAYPM---ASISP----PLPISCSSAQRLFIPNQSSFL
>Takifugu_rubripes_RBM46_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------VS-----------------------------CAEVVALLDLMEKTGYSMVQENGQRKYGGPPPG
W---EGPPPPRGC-----EVFVGKIPRDMY-EDELVPLFERAGKLYEFRLMMEFTG-ENRGYAFVMYTNKEAAQRAIQML
--------------------------------------DNYKVR-PGKFIGVCVSLDNCRLFIGSIPKEKTKDEVMAEMK
KVT----DGVVDVIMYPSSTDKSR-NRGFAFVEYKSHKAAAMARRKLIP-GTFQLWGQS-IQVDWAEPEKDVEEEVMQRV
-------------RVIYVRNLMLSTT----------------------EETLFQEFSH-FKPG-----------------
--------------------SVERVKKLTDYAFVHYYCREDALA--ALAIMNG---VQIDGA-----TIEVMLAKPATIK
EDSNGSRRHGNR---GYLGNS-----------------------------STAS-----------GGKVCMYRSNGGMMG
GASNEDGHL-----RT---MTLPS----------CDKDGLL--------------------------------------F
PLFPGTPLS------------------------PTSVLALKLS---QFTS-----AVSLLDVYCCKNNWSEPEYHLYSTP
GLDRTLLVLFKVVISSIN-------------------------STYIPNKLC---VLLEDAKELAAWTALWNLG------
-------------------------------------------TTPSSPSSPLTVSPPATNPG----------------M
LPCSSRAITPCL---SSSPHPPPPP---FHLSPLTHLP-TLSTPSYQ-----------
>Tetraodon_nigroviridis_RBM46_a
--------------------------------------------------------------------------------
------------------------------------------------------------M-------------------
-----------TDEVKAS-----------------------------CAEVVALLDLMEKTGYSMVQENGQRKYGGPPPD
W---EGPPPPRGC-----EVFVGKIPRDMY-EDELVPLFERAGKLYEFRLMMEFTG-ENRGYAFVMYTNKEAAQRAIQML
--------------------------------------DNYKVR-PGKFIGVCVSLDNCRLFLGSIPKEKTKDEVLAEMK
KLT----DGVVDVIMYPSSTDKSK-NRGFAFVEYKSHKAAAMARRKLIP-GTFQLWGQS-IQVDWAQPEKDVEEEVMQRV
-------------RVLYVRNLMLNTS----------------------EETLFKAFSH-FKPG-----------------
--------------------SVERVKKFTDYAFVHYYCREDALA--ALDPMNG---VLIDGA-----AVEVMLAKPAISK
EDSSGSRRHGSR---GYLKSN-----------------------------NTAG-----------GGK---YLTDQALDN
KDLNEGGPT-----HTNYCLVLP-----------GDRDGHF--------------------------------------F
PLFPGTPLS------------------------HTSVLALKPS---QFST-----AVSLLDVYCRQNNWLEPEYHLYSTP
GLDTTLLLLYKVVISSIH-------------------------STYMPGKLC---VLLDEAKELAAWTALWNLG------
-------------------------------------------TNIQTLLCLLCILNTSLNPIS---------------Q
KPLNSSFLSGAT---CESPSSPSSP---LALSPTATSPGMLTCSSKQRLYSPLNSETG
>Oryzias_latipes_RBM46_a
--------------------------------------------------------------------------------
----------------------------------------------------SEDADLLSS-------------------
-----------REDLKAS-----------------------------CAKEMALLALMEKTGYNMVQENGQRKYGGPPP-
-----GETRPQGC-----EVFVGKVPRDMY-EDELVPLFESAGRIYEFRLMMEFSG-ENRGYAFVMYTSREEAVRAIQML
--------------------------------------DGYEVR-PGRFIGVCVSLDNCRLFIGSIPRDRRKEEILEEMR
KVT----DGVVDVIVYPSSSDRNR-NRGFAFVEYESHKTAAMARRKLIP-GTFQLWGHP-IQVDWAEPEKDMEEEAMQRV
-------------RVLYVRNLMLDTT----------------------EETLRREFSR-FKPG-----------------
--------------------SVERVKKLTDYAFVHFRSRSEALA--TLAVMNG---VQIDGT-----TVEVSLAKPTGNK
EPVTFPLWRN-----EYIHPV-----------------------------SPKD-----------KRLDLLYCNIKESTP
PSLMKFSIF-----VG---GALK------------EPERCR--------------------------------------L
PLLPCTPLA------------------------PTSLLSLKPS---QINS-----AVTLLEYHCRRNCWPPPEYHLYSTP
DQDGNLLLLYKVVMPSAQ-------------------------GTFIPDKLC---LLLEDAKEVAAHNALWNL-------
--------------------------------------------------------------------------------
----------------------------------------------------------
>Branchiostoma_floridae_RBM46
--------------------------------------------------------------------------------
--------------------------------------------------MSENDANPQ---------------------
-----------GPQGITG-----------------------------AQNEAALLSLMERTGYNIIQENGQRKYGGPPPG
W---EGVTPSRGC-----EVFVGKIPRDLF-EDELVPVFESIGKIYELRLMMDFNG-NNRGYAFVMYTSRDDAKRAVKQL
--------------------------------------NNYEIR-KGRLLGVCPSVDNCRLFVGGIPKNKKKHEILEEMS
KVT----EGVVDVIVYPSATDKTK-NRGFAFVEYESHRAAAMARRKLIP-GRIQLWGHQ-IAVDWAEPEVEVDEDIMKSV
-------------KVLYVRNLLLTTT----------------------EESLKESFENVVSPG-----------------
--------------------SVERVKKIRDYAFVHFKTREEAVK--AMNATNG---QLIDGC-----QVEVTLAKPVDRD
NYVRYTRGAGRGMPMEIYPTGYEN--------------------YYIPTPYPPT---------HLYPAAAAAAAAFAP--
ANLRFQ-GRSSLGARGVMR---VRG------RGAAGA-RGAGGSRGYFSYGLT---RGG---------FYGQKK--KELF
DLLPGMELT------------------------PTNPVTMKPL-----KS-----APQMLEEMCQKNQWGSPVYSLHSTM
GPGERQLFLYKVTVPALASQ-------------------YPSAQPFQPTKLA---PSVEEAKSVAAEFVLNQLGI-----
--------------------------------------------PLDVSSE---VPLAAMAATA----------------
----------------------------------------------------------
>Homo_sapiens_RBM47
--------------------------------------------------------------------------------
--------------------------------------------------MTAEDSTA--AMSSDS----A---------
-----AGSSAKVPEGVAG-----------------------------APNEAALLALMERTGYSMVQENGQRKYGGPPPG
W---EGPHPQRGC-----EVFVGKIPRDVY-EDELVPVFEAVGRIYELRLMMDFDG-KNRGYAFVMYCHKHEAKRAVREL
--------------------------------------NNYEIR-PGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIA
KVT----EGVLDVIVYASAADKMK-NRGFAFVEYESHRAAAMARRKLMP-GRIQLWGHQ-IAVDWAEPEIDVDEDVMETV
-------------KILYVRNLMIETT----------------------EDTIKKSFGQ-FNPG-----------------
--------------------CVERVKKIRDYAFVHFTSREDAVH--AMNNLN---GTELEGS-----CLEVTLAKPVDKE
QYSRYQKAARGGG-AAEA---AQ----------------------QPSYVYSCD----------PYTLAYYGYPYNALIG
PNRDYFVKAGSIRGRGRGAAGNRAPGPRGSYLGGYSAGRGIYS-----------------------RYHEGKGKQQEKGY
ELVPNLEIPT------------------------VNPVAIKPG-TVAIPAIGAQYS-MFPAAPAPKMIEDGKIHTVEHMI
SPIAVQPDPASAAAAAAAAAAAAAA---------------VIPTVSTPPPFQ--GRPITPVYTVAPN--VQRIP------
-----------------------------------------------TAG-IYGASYVPFAAP-----------------
ATATIATLQKNA---AAAAAMYGGYAGYIPQ-AFPAAAIQVPIPDVYQTY--------
>Mus_musculus_RBM47
--------------------------------------------------------------------------------
--------------------------------------------------MTAEDSAT--AMNSDP----T---------
-----VGSSTKVPEGVAG-----------------------------APNEAALLALIERTGYTMVQENGQRKYGGPPPG
W---EGPHPQRGC-----EVFVGKIPRDVY-EDELVPVFETVGRIYELRLMMDFDG-KNRGYAFVMYCHKHEAKRAVREL
--------------------------------------NNYEIR-PGRLLGVCCSVDNCRLFIGGIPKMKKRGEILEEIA
KVT----EGVLNVIVYASAADKMK-NRGFAFVEYESHRAAAMARRKLMP-GRIQLWGHQ-IAVDWAEPEIDVDEDVMQTV
-------------KILYVRNLMIETT----------------------EETIKKSFGQ-FNPG-----------------
--------------------CVERVKKIRDYAFVHFTSREDAVH--AMNNLN---GTELEGS-----CLEVTLAKPVDKE
QYSRYQKAAKGGG-GSAEA-VAQ----------------------QPSYVYSCD----------PYTLAYYGYPYNALIG
PNRDYFVKTGSIRGRGRGAAGNRTPGPRGSYLGGYSAGRGIYS-----------------------RYHEGKGKQQEKGY
ELVPNLEISP------------------------VNPVAIKPG-TVAIPAIGAQYS-MFQAAPAPKIIEDGKIHTMEHMI
SPIAVQPDPATAAAAAAAAAAAA-----------------VIPAVSTPPPFQ--GRPITPVYTVAPN--VQRIP------
-----------------------------------------------TAG-IYGASYVPFAAP-----------------
ATATIATLQKN-----AAAAVYGGYAGYIPQ-AFP-AALQVPIHDVYQTY--------
>Canis_familiaris_RBM47
--------------------------------------------------------------------------------
--------------------------------------------------MTAEDAAA--AMSSDSA---AG--------
-----GAASAKAPEGVAG-----------------------------APNEAALLALLARTGYRMVQENGQRKYGGPPPG
W---EGPHPQRGC-----EVFVGKIPRDVY-EDELVPVFEAVGRIYELRLMMDFDG-KNRGYAFVTYCHKGEAKRAVREL
--------------------------------------NNHEIR-PGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIA
KVT----EGVLDVIVYASAADKMK-NRGFAFVEYESHRAAAMARRKLMP-GRIQLWGHQ-IAVDWAEPEIDVDEDVMETV
-------------KILYVRNLMIETT----------------------EDTIKKSFGQ-FNPG-----------------
--------------------CVERVKKIRDYAFVHFASREDAVL--AMNSLN---GTELEGS-----CLEVTLAKPVDKE
QYSRYQKAAKGGG--AAEA-AAP----------------------QPGYVYSCD----------PYTLAYYGYPYNALIG
PNRDYFVKAGSIRGRGRGAAGSRAPGPRGSYLGGYSAGRGIYS-----------------------RYHEGKGKQQEKGY
ELVPNLEISA------------------------VNPVAIKPG-TVAIPAIGAQYS-MFQAAPAPKMIEDGKIHTMEHMI
SPIAVQPDPASAAAAAAAAAAA------------------VIPAVSTPPPFQ--GRPITSVYTVAPN--VQRIP------
-----------------------------------------------AAG-LYGAGYVPFAAP-----------------
ATATLATLQKN----AAAAAVYGGYAGYIPQ-AFPAATIQVPIHDVYPTY--------
>Bos_taurus_RBM47
--------------------------------------------------------------------------------
--------------------------------------------------MTAEDSTA--AMSSDS----A---------
-----TGSSAKVPEGVAG-----------------------------APNEAALLALMERTGYSMVQENGQRKYGGPPPG
W---EGPHPQRGC-----EVFVGKIPRDVY-EDELVPVFETVGRIYELRLMMDFDG-KNRGYAFVMYCHKNEAKRAVREL
--------------------------------------NNYEIR-PGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIA
KVT----EGVLDVIVYASAADKMK-NRGFAFVEYESHRAAAMARRKLMP-GRIQLWGHQ-IAVDWAEPEIDVDEDVMETV
-------------KILYVRNLMIETT----------------------EDTIKKSFGQ-FNPG-----------------
--------------------CVERVKKIRDYAFVHFASREDAVH--AMNNLN---GTELEGS-----CLEVTLAKPVDKE
QYSRYQKAAKGGG-AAEAA-VVQ----------------------QPSYVYSCD----------PYTLAYYGYPYNALIG
PNRDYFVKAGSIRGRGRGAAGNRAPGPRGSYLGGYSAGRGIYS-----------------------RYHEGKGKQQEKGY
ELVPNLEISA------------------------VNPVAIKPG-TVAIPAIGAQYS-MFQAAPAPKMIEDGKIHTMEHMI
SPIAVQPDPASAAAAAAAAAA-------------------VIPAVSTPPPFQ--GRPITPVYTVAPN--VQRIP------
-----------------------------------------------TAG-IYGASYVPFAAP-----------------
ATATIATLQKNA---AAAAAMYGGYAGYIPQ-AFPAAAIQVPIHDVYQTY--------
>Equus_caballus_RBM47
--------------------------------------------------------------------------------
--------------------------------------------------MTAEDSTA--AMSSDS----A---------
-----AASSAKCPR-RAG-----------------------------ALNEAAAG-LSEAPGYSMWQETGSANTAAPPPG
W---GGTAPQRGC-----E-FVGKIPRDVY-EDE-VPVFEAG-RIYELRLMMDFDG-KNRGYAFVMYCHKNEAKRAVREL
--------------------------------------NNYEIR-PGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIA
KVT----EGVLDVIVYASAADKMK-NRGFAFVEYESHRAAAMARRKLMP-GRIQLWGHQ-IAVDWAEPEIDVDEDVMETV
-------------KILYVRNLMIETT----------------------EDTIKKSFGQ-FNPG-----------------
--------------------CVERVKKIRDYAFVHFTSREDAVH--AMNNLN---GTELEGS-----CLEVTLAKPVDKE
QYSRYQKAAKGGG-AAEAA-AVQ----------------------QPSYVYSCD----------PYTLAYYGYPYNALIG
PNRDYFVKAGSIRGRGRGAAGNRAPGPRGSYLGGYSAGRGIYS-----------------------RYHEGKGKQQEKGY
ELVPNLEISA------------------------VNPVAIKPG-TVAIPAIGAQYS-MFQAAPAPKMIEDGKIHTMEHMI
SPIAVQPDPASAAVAAAAAAA-------------------VIPAVSTPPPFQ--GRPITPVYTVAPN--VQRIP------
-----------------------------------------------TAG-IYGASYVPFAAP-----------------
ATATIATLQKNA---AAAAAVYGGYAGYIPQ-AFPAAAIQVPIHDVYQTY--------
>Gallus_gallus_RBM47
--------------------------------------------------------------------------------
--------------------------------------------------MTAEDSAA--RMSNDST---NV--------
-----STTKV--PEGVAG-----------------------------APNEAALLALMERTGYSMIQENGQRKYGGPPPG
W---DGLHPPRGC-----EVFVGKIPRDVY-EDELVPVFESVGRIYEMRLMMDFDG-KNRGYAFVMYTQKHEAKRAVREL
--------------------------------------NNYEIR-PGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIA
KVT----EGVLDVIVYASAADKMK-NRGFAFVEYESHRAAAMARRKLMP-GRIQLWGHQ-IAVDWAEPEIDVDEDVMETV
-------------KILYVRNLMIETT----------------------EDTIKKVFGQ-FNPG-----------------
--------------------CVERVKKIRDYAFVHFTTREDAIH--AMNNLN---GVELEGS-----CLEVTLAKPVDKE
QYTRYQKAAKGGAAATPEV-T-Q----------------------QPNYVYSCD----------PYTLAYYGYPYNALIG
PNRDYFVKAGSIRGRGRGAAGNRAPGPRGSYLGGYSAGRGIYS-----------------------RYHEGKGKQQEKGY
ELVPNLELPA------------------------VNPVAIKPG-AVAIPAIGAQYS-MFPAAPPAKMMEDGKIHAVEHII
NPIAVQQDPAS-AAAAAAAAAA-----------------AVIPAVSTPPPFQ--GRPITPVYTMAPN--VQRIP------
-----------------------------------------------AAG-IYGTSYVPFAAPA---------------A
ATATIATLQKNAAAAAAAAAAYGGYAGYIPP-AFPAATIQVPIHDVYQTY--------
>Anolis_carolinensis_RBM47
--------------------------------------------------------------------------------
--------------------------------------------------MTAEDSTA--RMNNDSS---KM--------
-----QANKVHIPEELAN-----------------------------VPNGPALIQLMERTGYNLVQENGQRKYGGPPPG
W---EGLHPPRGC-----EVFVGKIPRDVY-EDELVPVFETAGRIYEMRLMMDFDG-KNRGYAFVMYTQKYEAKRAVKEL
--------------------------------------NNYEIR-PGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIS
KVT----EGVLDVIVYASAADKMK-NRGFAFVEYESHRAAAMARRKLMP-GRIQLWGHQ-IAVDWAEPEIDVDEDVMETV
-------------KILYVRNLMIETT----------------------EDTIKKVFGQ-FNPG-----------------
--------------------CVERVKKIRDYAFVHFTSREDAVQ--AMNNLN---NTELEGS-----CLEVTLAKPVDKE
QYTRYQNSSQRG-TTTTEV-T-Q----------------------QPNYVYSCD----------PYTLAYYGYPYNALIG
PNREYFVKAGSVRGRGRGAAGNRTPGPRGSYFGGYSAGRGIYS-----------------------RYHEGKGKQQEKGY
ELVPNLDLSA------------------------VSPVAIKPG-TVAIPTIGTQYS-MFQAAPTAKMLEDGKIHAVEHII
SPIAVQQDPASAAAAAAAAAAAG----------------AVMPAVSTPPPFQ--GRPITPVYTMAPN--MQRIP------
-----------------------------------------------AAG-IYGASYVPFAAPA---------------A
ATATLATLQKN-AAAAAAAAAYGGYAGYIPQ-AFPAATIQVPIHDVYQTY--------
>Xenopus_tropicalis_RBM47
--------------------------------------------------------------------------------
--------------------------------------------------MTAEDSTA--MISNESS-------------
-----NMSTSNIPEGVAG-----------------------------APNEAALINLMERTGYTMVQENGQRKYGGPPPG
W---EGSPPPRGC-----EVFVGKIPRDVY-EDELVPVFESAGRIFEMRLMMDFDG-KNRGYAFVMFTKKHEAKQAVREL
--------------------------------------NNYEIR-PGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIS
KVT----EGVLDVIVYASAADKMK-NRGFAFVEYESHRAAAMARRKLMP-GRIQLWGHQ-IAVDWAEPEIDVDEDVMETV
-------------KILYVRNLMIETS----------------------EDTIKKIFGQ-FNPG-----------------
--------------------CVERVKKIRDYAFVHFSSREDAVQ--SMRKLN---GTELEGS-----CIEVTLAKPVDKE
QYTRYQKAAKGGAPATATATEVT----------------------QPNYIYSCD----------PYTLAYYGYPYNALIG
PNRDYFVKAGSLRGRGRGAAGNRSPGPRGAYLGGYSAGRGIYS-----------------------RYHEGKGKPQEKGF
ELVPNLELPA------------------------VNPVALKPG-TVAIPTIGTQYS-MFQAASAAKLLEEGKIHGMEHMI
NPMAVQADPAAAAAAAAAAAA-------------------VIPSVSTPPPFQ--GRPITPVYTMAPN--VQRIP------
-----------------------------------------------AAG-IYGASYLPIAAP-----------------
ATAALATLQKN------TAAVYGGYAGYIPQ-AFPAATIQVPLHDIYPTY--------
>Danio_rerio_RBM47_a
--------------------------------------------------------------------------------
--------------------------------------------------MTAEDSASAVAMSNPSPSSSSK-------S
SSGHPQH-HCTVPEGVAG-----------------------------APNEAALVSLMERSGYGMVQENGQRKYG-PPPG
W---QGTSPPRGC-----EIFVGKIPRDVY-EDELVPVFESVGRIYEMRLMMDFDG-KNRGYAFVMYTQKHEAKRAVREL
--------------------------------------NNFEIR-PGRLLGVCSSVDNCRLFIGGIPKTKKREEILEEVS
KVT----EGVLDVIVYASAADKMK-NRGFAFVEYESHRAAAMARRKLMP-GRIQLWGHQ-IAVDWAEPEIDVDEDVMETV
-------------KILYVRNLMIETS----------------------EEILRQTFGQ-FNPG-----------------
--------------------CVERVKKIRDYAFVHFASRDDAVV--AMDNLN---GTEIEGS-----RIEVTLAKPVDKE
QYTRYQKASKGTAAATTVEST------------------------QQSYVYQCD----------PYTLAYYGYPYNTLIG
PNRDYFIKAGTVRGRGRAGASSRGPGPRGSYLGGYSAGRGIYS-----------------------RYHEGKTKLPDKPY
EIMSNLELAA------------------------VNPVGIKPG-TMALPALGAQYPTVFSAAPATKLMEEGKIHPVEHLI
NPLALQH-DPTAASATAA----------------------VIPAVSTPPPFQ--GRPITPVYAMAHN--IQRIPA-----
-----------------------------------------------AAASLYGAGYMPIAAH----------------A
NTATLAALQKN---AAV-AAAYGGYAGY-MPQAFPAATFQMPIHDVYQTY--------
>Takifugu_rubripes_RBM47_a
--------------------------------------------------------------------------------
--------------------------------------------------MTAEDPTPSSAMSHNTAPSKAS-------S
ASHHSFHGQVSIPEGVAG-----------------------------TPNEAALVALMERTGYGMVQENGQRKYG-PPPG
W---NGPSPPRGC-----EIFVGKIPRDVY-EDELVPVFESVGRIYEMRLMMDFDG-KNRGYAFVMYTEKHEAKRAVREL
--------------------------------------NNYEVR-PGRLLGVCSSVDNCRLFIGGIPKTKKREEILEEVS
KVT----EGVIDVIVYASAADKMK-NRGFAFVEYESHRAAAMARRKLMP-GRIQLWGHQ-IAVDWAEPEIDVDEDVMETV
-------------KILYVRNLMMETS----------------------EETIRKVFSQ-WNPG-----------------
--------------------CVERVKKIRDYAFVHFNSRDDAVL--AMNHLN---GTEVEGS-----CIEVTLAKPVDKE
QYSR-QKASKGAP-ATPEAT-------------------------QQNYVYQCD----------PYTLAYYGYPYSTLIG
PNREYFIKEVLCRGRGRPIAGNRTPGPRGSYLGGYSAGRGIYS-----------------------RYHDGKTKQPEKPH
ELMPSLELAAS-----------------------VNPVGIKPG-TMALPALGAQYP-VFSAPPAAKLMEEGKVHTVEHLI
NPLAMQHPEHTNTPAAAT----------------------VLPAVSTPPPFQ--GRPITPVYAMAHN--VQRIPT-----
-----------------------------------------------AGG-LYGAGYIPIANYA---------------A
NSAALAALQKN---AAVAAAAYGGYSTYTVPQAFPTTAFQLPIHDVYQTY--------
>Tetraodon_nigroviridis_RBM47_a
--------------------------------------------------------------------------------
--------------------------------------------------MTAEDPAPSSAMSNNAAPSKTS-------G
ASHHSFHGQVSVTEGVAG-----------------------------APNEPALVALMERTGYNMVQENGQRKYG-PPPG
W---NGPSPQRGC-----EIFVGKIPRDVY-EDELVPVFESVGRIYEMRLMMDFDG-KNRGYAFVMYTEKHEAKRAVREL
--------------------------------------NNYEVR-PGRLLGVCSSVDNCRLFIGGIPKTKKREEILEEVS
KVT----EGVIDVIVYASAADKMK-NRGFAFVEYESHRAAAMARRKLMP-GRIQLWGHQ-IAVDWAEPEIDVDEDVMETV
-------------KILYVRNLMMETS----------------------EETIRKVFSQ-WNPG-----------------
--------------------CVERVKKIRDYAFVHFNSRDDAVL--AMNQLN---GTEVEGS-----CIEVTLAKPVDKE
QYSR-QKASKGAA-ATPEAT-------------------------QQNYVYQCD----------PYTLAYYGYPYNTLIG
PNREYFIKAGTVRGRGRAVAGNRTPGPRGSYLGGYSAGRGIYS-----------------------RYHEGKTKQPEKPH
ELMPSLELAAS-----------------------VNPVSIKPG-TIALPALGGQYP-MFSAPPAAKLIEEGKVHAVEHLI
NPLTMQHPEHTNTTAAAT----------------------VLPAVSTPPPFQ--GRPITPVYAMAHN--VQRIPT-----
-----------------------------------------------AGG-LYGAGYVPIANYA---------------A
NSAALAALQKN---AAVAAAAYGGYSAYTVPQAFPATAFQLPIHDVYQTY--------
>Gasterosteus_aculeatus_RBM47_a
--------------------------------------------------------------------------------
--------------------------------------------------MTAEDPASSSTMSNNAAPTKPPQPA----G
ASHPSLHGQINTPEGVAG-----------------------------SPIEPALVSLMERTGYSMVQENGQRKYG-PPPG
W---NATSPPRGC-----EIFVGKIPRDVY-EDELVPVFESVGRIYEMRLMMDFDG-KNRGYAFVMYTEKHEAKRAVREL
--------------------------------------NNYEVR-PGRLLGVCSSVDNCRLFIGGIPKTKKREEILDEVS
KVT----EGVLDVIVYASAADKMK-NRGFAFVEYESHRAAAMARRKLMP-GRIQLWGHQ-IAVDWAEPEIDVDEDVMETV
-------------KILYVRNLMMETS----------------------EETIRQVFSQ-WNHG-----------------
--------------------CVERVKKIRDYAFVHFTSREDAVM--AMDHLN---GTEVEGS-----CIEVTLAKPVDKE
QHSR-QKASKGTP-ATPEPA-------------------------PQNYVYQCD----------PYTLAYYGYPYNTLIG
PNRDYFVKAGTVRGRGRAAAGNRTPGPRGSYLGGYSAGRGIYS-----------------------RYHEGKAKQPEKPY
ELMPTLELAAS-----------------------VNPVGIKHG-AMALQTLGGQYP-VFSAAPTAKLMEEGKVHTVEHLI
NPLAMQHADHTAATAAAT----------------------VMPSVSTPPPFQ--GRPITPVYAMAHN--VQRIPT-----
-----------------------------------------------AAG-LYAGGYVPITNYA---------------A
NSAALAALQKN---AAVAAAAYGGYAGYAMPQAFPAAAFQLPIHDVYQTY--------
>Oryzias_latipes_RBM47_a
--------------------------------------------------------------------------------
--------------------------------------------------MTAEDPAASSTMSNNAAHAKPS-------A
ASHHSLHGHINIPEGVAG-----------------------------ASNEAALVTLMERTGYTMVQENGQRKYG-PPPG
W---NGPSPPRGC-----EIFVGKIPRDVY-EDELVPVFESVGRIYEMRLMMDFDG-KNRGYAFVMYTEKHEAKRAVREL
--------------------------------------NNYEVR-PGRLLGVCSSVDNCRLFIGGIPKTKKREEILEEVS
KVT----EGVLDVIVYASAADKMK-NRGFAFVEYESHRAAAMARRKLMP-GRIQLWGHQ-IAVDWAEPEIDVDEDVMETV
-------------KILYVRNLMMETN----------------------EETIRQIFSQ-WNPG-----------------
--------------------CVERVKKIRDYAFVHFTSRDDAVL--AMDNLN---GTEIEGS-----CIEVTLAKPVDKE
QYSR-QKASKGAIPATPEATQ------------------------QQNYVYQCD----------PYTLAYYGYPYSTLIG
PNRDYFVKAGTVRGRGRAAAGNRTPGPRGSYLGGYSAGRGIYS-----------------------RYHEGKTKQPEKPY
ELMNSLELPAS-----------------------VNPVGIKPG-TMALPALGAQYP-VFSPTPAPKLMEDGKVHTVEHLI
NPLAIQHPEHT-TAAAAT----------------------VLPAVSTPPPFQNQGRPITPVYAMAHN--VQRIPT-----
-----------------------------------------------AGG-LYGPGFVPITNYT---------------A
NTAALAALQKN---AAMTAAAYGGYAGYAVPQAFPAAAFQLPLHDIYQTY--------
>Ciona_intestinalis_RBM47
--------------------------------------------------------------------------------
-------------------------------------------MVIDETSAVCNGPD-----------------------
-----------NENGLSG-----------------------------VPNEAALVALMKRTGYSITQENGQRKYGGPPPG
W---ENKPPPRGA-----EVFVGKIPRDVF-EDELVPVFETAGRIYEMRLMMDFDG-KNRGYAFVMFTAKSDAKGAVKKL
--------------------------------------NNYEIR-KGRMLGVCYSVDNCRLFVGGIPKTKKKDDIFAEMT
KVT----EGVTDVIVYPSASDKTK-NRGFAFVEYDSHRAAAMARRKLIP-GRIQLWGHP-IAVDWAEPEQDVDDEIMGQV
-------------KVLYVRNLMLDTT----------------------EDTLQNVFSQ-FKPG-----------------
--------------------SVERVKKIRDYAFVHFSTREACIE--AMEKING---THIDQA-----EVEVTLAKPVDKS
DYNRMAKVGAKVLNGTETS------------------------TPTQSLVQAPT-V------VNQNGMLVYPAGVYGN--
DIAYYSLGQYNLATGARPIYPTRGGLRTDRGRGAAGT-RAPSGRNSYLGYSAGKATYGR-------YYSKNNQ--ERPVA
ADTAGLELI------------------------TQVATIPQVVP-TMVKS-----SDIILEEICQRQMWGSPSYQLLTTT
GGDGRQLFLYKVSIPALASI-------------------FPTQPYFQPNKLC---VTVEEAKSYAAEYVLSQLAL-----
--------------------------------------------QADG--------------------------------
------TPAVVP---MATVFQQPSAPAAPYP---------------------------
>Ciona_savignyi_RBM47
--------------------------------------------------------------------------------
-----------------------------------------------------NGTT-----------------------
-----------VGNGLAG-----------------------------VPNEATLIALTTRTGYSITQENGQRKYGGPPPG
W---ENKPPPRGA-----EVFVGKIPRDVF-EDELVPVFETAGRIYEMRLMMDFDG-KNRGYAFVMFTTKSEAKGAVKKL
--------------------------------------NNYEIR-KGRMLGVCYSVDNCRLFVGGIPKTKKKDDIFAEMN
KVT----EGVIDVIVYPSASDKTK-NRGFAFVEYDSHRAAAMARRKLIP-GRIQLWGHP-IAVDWAEPEQDVDDEIMGQV
-------------KVLYVRNLMLDTT----------------------EDTLQNVFSQ-FKPG-----------------
--------------------SVERVKKIRDYAFVHFSTREACME--AMAKING---TEIDYA-----EVEVTLAKPVDKN
DYNRMAKVGAKVLNGSETTSSAAQSMV----------------SSLISFVSSPA-V------VNQNGVIVYPAGVYNN--
DIAYYSLGQYNLATGARPIYPTRG-------RGAGGA-RGASSRNSYLGYSAGKATYGR-------YYSKNNQ--ERP--
--AEGLELI------------------------TQQPTV--ING-QVIPA-----SDVVLEEICQRHMWGNPTYQLLTTA
GPDSRQLFLYKVSIPALASI-------------------FPQQPYFQPNKLC---VTVEEAKSYAAEYVLSQLAL-----
--------------------------------------------QPDG--------------------------------
------SPAVVP---LATVLPQATAAAAPYPVS-------------------------
>Strongylocentrotus_purpuratus_RBM47
--------------------------------------------------------------------------------
--------------------------------------------------MEGSPTKS----------------------
-----------DPEGISG-----------------------------ARNEAALLTLMERTGYHIVQENGQRKYGGPPPG
W---EGAQPSRGC-----EVFVGKIPRDLF-EDELVPVFMKIGKIYELRLMMDFSG-SNRGYAFVMYTTREDGKKAVKQL
--------------------------------------NNYEIR-KGRYLGVCPSVDNCRLFVGGIPKNKKQEEILAEMA
KVT----EQVVDVIVYPSINDKAK-NRGFAFVEYENHRAAAMARRKLIP-GRIQLWGHQ-IMVDWAEPEQDVDEDVMRGV
-------------KILYVRNLMLHTT----------------------EETIAKEFNA-FKEG-----------------
--------------------SVERVKKLRDFAFIHFFTREDALN--AMNAMDD---PLLDGA-----KIEVVLAKPVDKG
NYVRYTPGAGRG---YVQQGLYG---------------------YEQQQQQQSSPS------YYPG---YSNPTGMPP--
-MMGMGGRGGGMMQRSPIRGGTRGR------GGAGGM-RGAGGTRSYGMGRG----------------------------
----------------------------------YNRYDRKPQ--------------EVLEELCNKNQWGPPSFTLLSHR
TNSDVQLFIYKVTVPGLSAN-------------------YP--DGLTPQKLC---QTPDQAKNFAAECLLASLGV-----
--------------------------------------------PVDGEL------------------------------
----------------------------------------------------------
>Homo_sapiens_DND1
--------------------------------------------------------------------------------
--------------------------------------------------MQSKRD------------------------
--------CELWCERVNP------------------------------ENKAALEAWVRETGIRLVQVNGQRKYGGPPPG
WV---GSPPPAGS-----EVFIGRLPQDVY-EHQLIPLFQRVGRLYEFRLMMTFSG-LNRGFAYARYSSRRGAQAAIATL
--------------------------------------HNHPLR-PSCPLLVCRSTEKCELSVDGLPPNLTRSALLLALQ
PLG----PGLQEARLLPSPGPAP---GQIALLKFSSHRAAAMAKKALVE-GQSHLCGEQ-VAVEWLKPDLKQRLRQQLVG
P---------------FLRSPQP------------------------EGSQLALARDK----------------------
------------------------LGFQGARATLQLLCQRMKLG--SPVFLTKCLGIGPAGWHR-FWYQVVIPGHPVPFS
GLIWVVLTLDGR----------------------------------------------------DGHEVAKDAVSVRLLQ
ALS-ESGANLLWSAGAEAG-TMVKQ-------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------
>Canis_familiaris_DND1
--------------------------------------------------------------------------------
--------------------------------------------------MQSKRE------------------------
--------CELWCERVNP------------------------------ENKAALEAWVRETGIRLVQVNGQRKYGGPPPG
WV---GSPPPAGS-----EVFIGRLPQDVY-EHQLIPLFQRVGRLYEFRLMMTFSG-LNRGFAYARYSSRRGAQAAIATL
--------------------------------------HNHPLR-PSCPLLVCRSTEKCELSVDGLPPGLSRRALLLALQ
PLG----SGLQEALLMPSPGPAP---AQIALLKFSSHRAAAMAKKALVE-GQSRLCGEQ-VSVEWLKPDLKQRLRQQFMG
P---------------SLQGLQP------------------------EGSRLAPSRDK----------------------
------------------------LESQGARATLQLLCQQMKLG--SPVFLTKCLGTGPAGWHR-FWYQVVIPGHPVPFS
GLIWVVLAPEGQ----------------------------------------------------EGHEVAKDAVSARLLE
ALR-ESGAGLFRSAGAEAG-MVVKQ-------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------
>Bos_taurus_DND1
--------------------------------------------------------------------------------
--------------------------------------------------MQSKRE------------------------
--------CELWCERVNP------------------------------ENKAALEAWVRETGIRLVQVNGQRKYGGPPPG
WV---GSPPPAGS-----EVFIGRLPQDVY-EHQLIPLFQRVGRLYEFRLMMTFSG-LNRGFAYARYSSRRGAQAAIATL
--------------------------------------HNHLLR-PSCPLLVCRSTEKCELSVDGLPPGLSHRALLRALQ
PLG----PGLQEALLLPSPGPTP---AQIALLKFSSHRAAAMAKKALVE-GQSHLCGEQ-VAVEWLKPDLKQRLRQQLMG
T---------------SLQCLQP------------------------EGNRLALARDQG---------------------
------------------------LEFQGSQVALQLLCQRMKLG--SPVFLTKCLGTSPAGWHR-FWYQVVIPGHPVPFS
GLIWVVLTPDGQ----------------------------------------------------DGHEVAKDAVSARLLE
AMS-ESRASLLWSTGAEAGGTMVQQ-------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------
>Equus_caballus_DND1
--------------------------------------------------------------------------------
--------------------------------------------------MQSKRE------------------------
--------CELWCERVNP------------------------------ENKAALEAWVRETGIRLVQVNGQRKYGGPPPG
WV---GSPPPAGS-----EVFIGRLPQDVY-EHQLIPLFQRVGRLYEFRLMMTFSG-LNRGFAYARYSSRRGAQAAIATL
--------------------------------------HNHPLR-PSCPLLVCRSTEKCELSVDGLPPALSRRALLLALQ
PLG----PGLQEALLLPSPGPAS---AQIALLKFSSHRAAAMAKKALVE-GQSRLCGEQ-VAVEWLKPDLKQRLRQQFVG
P---------------SLQCLQP------------------------ESSRLALARDR----------------------
------------------------LESQGARAALQLLCQRMKLG--SPVFLTKCLGTGPAGWHR-FWYQVVIPGHPVPFS
GLIWVVLAPDGQ----------------------------------------------------DGHEVAKDAVSTRLLE
ALS-ESGASLLWSAGAEAG-TVVKQ-------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------
>Xenopus_tropicalis_DND1
--------------------------------------------------------------------------------
---------------------------------------MATSAGSQADFLKGDYKRIENMELTDEQ-------------
-------KSQMWINSINS------------------------------ENKTALLAWVKETGIDLVQINGQRKYGGPPPG
WI---GNAPVSGS-----EVFIGKIPQDIY-EDKLIPLFQSIGKLYEFRLMMTFSG-LNRGFAYARYIGRRQAVSAIMTL
--------------------------------------NGYEIT-KGCCIVVCRSTEKSELALDGLPSHLEQPALKNILE
EVT----SGVSALSLYQSPSNES---QVLAIVKYDSHRAAAMAKKSLCE-GSQFLRGLP-LTVSWLKTDMRQKLRSSDKH
Q---------------QPKVPSP------LP---------------HSGSPEVPKETRL---------------------
----------------------------SAVACLNILCLKMKLG--YPVFLIKLFSVTSFGWLR-FWYQVVIPRYPTPFC
GYSWIIGENLELN---------------------------------------------------EKYDNAREVVAVKILS
ALG------HITDPSVEKATASNAM-------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------
>Danio_rerio_DND1_a
--------------------------------------------------------------------------------
-------------------------------------------------MVGDMDA------------------------
-------QQQELQQILNP------------------------------QKLKSLQEWMQRNSITLTQVNGQRKYGGPPPG
WQ---GPAPGSGC-----EVFISQIPNDVY-EDRLIPLFQSIGTIYEFRLMMNFSG-QTRGFAYAKYGDPLTASAAVTTL
--------------------------------------HQYRLP-EGGCLTVRRSTEKRQLRLGDLPVSMNESKLLMVLQ
MLS----DGVEDVLLKP-PGPKGK--EVVALVNYTSHYAASMAKKVLVE-AFRNRYGIS-ITVRWTS-FSKSKRVEDTPQ
E---------------DSCVTPLVLKPLSKPSLLHYDVPAHQSLLPLFRAVGGPTTSEQ-RDEMIPQPTIMSRNELIPQS
SIRQRDEMVPQLPIRPRDGMAPQSPISLDAVSHLQWMCEVNRLG--SPQYEVHFHHAAPDGFLY-FAFKVLIPGLPLPLY
GFVQILPGTSAR----------------------------------------------------AMKSEVYRAAAEQVIQ
TLCRVSNLRPF---------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------
>Takifugu_rubripes_DND1_a
--------------------------------------------------------------------------------
-------------------------------------------------LPPDMHA------------------------
-------TEFSVVDILNL------------------------------DRVKAFHEWLERTNTKITQVNGQRKYGGPPDK
WD---GPVPGARC-----EIYITHIPRDTY-EDVLIPLFTTVGPLWQFRLMMNFSG-QNRGFAYAKYGSPAIAASAIQLL
--------------------------------------HGHMIE-PGVSLCVRHSTEKRQLCIGGLPVSTKQADISQVMH
TMC----EGIERVSLKSEPGIAG----MSAVVTFSSHYTASMAKKVVIE-AFKNQYALR-VSVSWFSSFKASPNRLLPPQ
N---------------LVNVSCRSSVLLPRQ------TGTLFHSPSFCKAVGGPITPR----PYECSTPS----------
----------------------SRASLPSPMMLLNNLCQTAGFG--PPHYKISCSRAGPDGYLH-FSYQVFILGINMSLE
GVIMILPGANIS----------------------------------------------------STMEEAREAVAQQVLS
ICCLFCSMHAC---------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------
>Tetraodon_nigroviridis_DND1_a
--------------------------------------------------------------------------------
-----------------------------------------------------MAG------------------------
-------NHN---QMLNP------------------------------GEARKFEKWLKRTNTKLTQVNGQRKYGGPPEG
WD---GPTPGARC-----EVFITNIPRNTY-EDVLIPLFGTVGSLWEFRLMMNFSG-QNRGFAYAKYGSQVIAASAVQLL
--------------------------------------HGHVIK-PGVSLCVRPSTEKRQLSIGGLPVTTKHADLLQVLR
AMC----EGVETVSVKAEPGIAG----VSAIVTFSSHHAATNAKKLVME-EFKKQYAIK-VTINWLPAVNPTSHDVLPPQ
T---------------LVNVFCGSSELS--------------NSPGFCKAVGGP-TAA----QHGCSTTS----------
----------------------SLMSATSPTMLLDYLCRKNGFG--RPHCEISCHHAEPDGYLH-FSYKVFNRGMN-TLE
GVIMILPGVTAA----------------------------------------------------STMEEARRAVAQQVL-
-CKLFPNEVSY---------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------
>Gasterosteus_aculeatus_DND1_a
--------------------------------------------------------------------------------
--------------------------------------------------LPTK--------------------------
--------PPPPQKVLNH------------------------------ERVQALETWLRTTNAKLTQVNGQRKYGGPPQV
WD---GPAPGAHC-----EVFISQIPRDTY-EDLLIPLFSSVGPLWEFRLMMNFSG-QNRGFAYCKYGSPDVANEAIRLL
--------------------------------------HGYTIE-PTFRLNVRRSTEKRHLCIGDLPATTKQEALLKVLH
VLA----DGVERVSLKAGPGIDG----VSAMVAFSSHHAASMAKKMLVE-AFKKQFSLK-VSITWQSTHKRPPSLLPPPQ
K---------------PPRLTPSALPPR-------M-ARPPSFPQGFCRAVGGPAVP-----QHSARPSS----------
------------SPSPSQGR--PVSPPPSPVTFLHELCKATAVG--QPLYKTYFSHAGPDGFLF-FNYKVHFTGAPATFE
GLVMILPGPSAT----------------------------------------------------STLEEAQRAAAQQVLQ
--RLSNNQLA----------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------
>Oryzias_latipes_DND1_a
--------------------------------------------------------------------------------
-------------------------------------------------FLRDHNL------------------------
-------LPPPLPQVVNL------------------------------ERVQALQAWVKSTNTKLTQVNGQRKYGGPPDV
WD---GPPPGARC-----EVFISQIPRDVY-EDLLIPLFSSVGALWEFRLMMNFSG-QNRGFAYAKYGTAAIANDAIHLL
--------------------------------------HGYPLG-PGARLSVRCSIEKRQLCIQNLPASTRQEELLQVLR
LLS----AGVESVALKAGPGIEG----VSAVVAFSSHHAASMAKKALGE-GRKQLMGLQ-GAGPKTTRFKKK-SVQDSPK
V---------------PNRVRKPLLKPMHKKARLEF-ARAHAEKENLFVNYGGKPVTSSGRWQTACVTSCGQDGRLFPRS
KVKETTLMVVEXSLHPTDGLRGQVMFSVSPVLLLRKLSEASGWG--DPHYEMLFSHAGPDGFLY-FTYKVHVPGAPTTFR
GFVMILPGHCTS----------------------------------------------------TMLEEARRAAAQQVLQ
--KLC---------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------
>Homo_sapiens_A1CF
--------------------------------------------------------------------------------
--------------------------------------------------MESNHK------------------------
-----------SGDGLSG-----------------------------TQKEAALRALVQRTGYSLVQENGQRKYGGPPPG
W---DAAPPERGC-----EIFIGKLPRDLF-EDELIPLCEKIGKIYEMRMMMDFNG-NNRGYAFVTFSNKVEAKNAIKQL
--------------------------------------NNYEIR-NGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMK
KVT----EGVVDVIVYPSAADKTK-NRGFAFVEYESHRAAAMARRKLLP-GRIQLWGHG-IAVDWAEPEVEVDEDTMSSV
-------------KILYVRNLMLSTS----------------------EEMIEKEFNN-IKPG-----------------
--------------------AVERVKKIRDYAFVHFSNREDAVE--AMKALNG---KVLDGS-----PIEVTLAKPVDKD
SYVRYTRGTGGR--GTMLQGEYT---------------------YSLGQVYDPT-T------TYLGAPVFYAPQTYAA-I
PSLHFPATKGHLSNRAIIRAPSVREIYMNVPVGAAGV-RGLGG-RGYLAYTG----LGR------GYQVKGDKR-EDKLY
DILPGMELT------------------------PMNPVTLKPQ---GIKL-----APQILEEICQKNNWGQPVYQLHSAI
GQDQRQLFLYKITIPALASQ-------------------NPAIHPFTPPKLS---AFVDEAKTYAAEYTLQTLGI-----
--------------------------------------------PTDGGD--GTMATAAAAATAFPG--------YAVPN
AT-APVSAAQLK---QAVTLGQDLAAYTTYEVYPTFA-VTAR-GDGYGTF--------
>Mus_musculus_A1CF
--------------------------------------------------------------------------------
--------------------------------------------------MESNHK------------------------
-----------SGDGLSG-----------------------------TQKEAALRALVQRTGYSLVQENGQRKYGGPPPG
W---DSTPPERGC-----EIFIGKLPRDLF-EDELIPLCEKIGKIYEMRLMMDFNG-NNRGYAFVTFSNKQEAKNAIKQL
--------------------------------------NNYEIR-TGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMK
KVT----EGVVDVIVYPSAADKTK-NRGFAFVEYESHRAAAMARRRLLP-GRIQLWGHP-IAVDWAEPEVEVDEDTMSSV
-------------KILYVRNLMLSTS----------------------EEMIEKEFNS-IKPG-----------------
--------------------AVERVKKIRDYAFVHFSNREDAVE--AMKALNG---KVLDGS-----PIEVTLAKPVDKD
SYVRYTRGTGGR--NTMLQGEYT---------------------YPLSHVYDPT-T------TYLGAPVFYTPQAYAA-I
PSLHFPATKGHLSNRALIRTPSVREIYMNVPVGAAGV-RGLGG-RGYLAYTG----LGR------GYHVKGDKR-EDKLY
DLLPGMELT------------------------PMNTVSLKPQ---GIKL-----APQILEEICQKNNWGQPVYQLHSAI
GQDQRQLFLYKVTIPALASQ-------------------NPAIHPFIPPKLS---AYVDEAKRYAAEHTLQTLGI-----
--------------------------------------------PTEGGDA-GTTAPTATSATVFPG--------YAVPS
AT-APVSTAQLK---QAVTLGQDLAAYTTYEVYPTFA-LTTR-GDAYGTF--------
>Canis_familiaris_A1CF
--------------------------------------------------------------------------------
--------------------------------------------------MESNHK------------------------
-----------SGDGLSG-----------------------------TQKEAALRALVQRTGYSLVQENGQRKYGGPPPG
W---DAAPPERGC-----EIFIGKLPRDLF-EDELIPLCEKIGKIYEMRMMMDFNG-NNRGYAFVTFSNRQEAKDAIKQL
--------------------------------------NNYEIR-NGRLLGVCASVDNCRLFVGGIPKTKKREEILAEMK
KVT----EGVVDVIVYPSAADKTR-NRGFAFVEYESHRTAAMARRKLLP-GRIQLWGHP-IAVDWAEPEVEVDEDTMSSV
-------------KILYVRNLMLSTS----------------------EEMIEKEFNN-IKPG-----------------
--------------------AVERVKKIRDYAFVHFSNREDAVE--AMKALNG---KMLDGS-----PIEVTLAKPVDKD
SYVRYTRGTGGR--GSMLQGEYT---------------------YSLGHVYDPT-T------TYLGAPVFYAPQAYTA-I
PSLHFPATKGHLGNRAIIRAPSVREIYMNVPVGAAGV-RGLAG-RGYLAYTG----LGR------GYQVKGDKR-EDKLY
DLLPGMELT------------------------PMNPVTLKPQ---GIKL-----APQILEEICQKNNWGQPVYQLHSAI
GQDQRQLFLYKITIPALANQ-------------------NPTIHPFTPPKLS---AYVDEAKTYAAEYTLQTLGI-----
--------------------------------------------PTDGAD----APTA-AAATAFPG--------YAVPN
AT-APVSAAQLK---QAVTLGQDLA-YTTYEVYPTFA-VTAR-GDGYGAF--------
>Bos_taurus_A1CF
--------------------------------------------------------------------------------
--------------------------------------------------MESNHK------------------------
-----------SGDGLSG-----------------------------TQKEAALRALVQRTGYSLVQENGQRKYGGPPPG
W---DAAPPERGC-----EIFIGKLPRDLF-EDELIPLCEKIGKIYEMRMMMDFNG-NNRGYAFVTFSNKQEAKNAIKQL
--------------------------------------NNYEIR-NGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMK
KVT----EGVVDVIVYPSAADKTK-NRGFAFVEYENHRAAAMARRKLLP-GRIQLWGHP-IAVDWAEPEVEVDEDTMSSV
-------------KILYVRNLMLSTS----------------------EEMIEKEFNN-IKPG-----------------
--------------------AVERVKKIRDYAFVHFTNREDAVE--AMKALNG---KVLDGS-----PIEVTLAKPVDKD
SYVRYTRGTGGR--GAMLQGEYT---------------------YSLGHVYDPT-T------TYLGAPVFYAPQAYTA-I
PSLHFPTTKGHLGNRAIIRAPSVREIYMNVPVGAAGV-RGLGG-RGYLAYTG----LGR------GYQVKGDKR-EDKLY
DLLPGMELT------------------------PMNPVTLKPQ---GIKL-----APQILEEICQKNNWGQPVYQLHSAI
GQDQRQLFLYKITIPALASQ-------------------NPAIHPFTPPKLS---AYVDEAKTYAAEYTLQALGI-----
--------------------------------------------PTDGADA-QTAAAAAASATAFPG--------YAVPS
PT-ASVSAAQLK---QAVTLGQDLAAYAAYEVYPTFA-VTAR-GDGYGTF--------
>Equus_caballus_A1CF
--------------------------------------------------------------------------------
--------------------------------------------------MESNHK------------------------
-----------SGDGLSG-----------------------------TQKEAALRALVQRTGYSLVQENGQRKYGGPPPG
W---DAAPPERGC-----EIFIGKLPRDLF-EDELIPLCEKIGKIYEMRMMMDFNG-NNRGYAFVTFSNKQEAKNAIKQL
--------------------------------------NNYEIR-NGRLLGVCASVDNCRLFVGGIPKTKKREEILLEMK
KVT----EGVVDVIVYPSAADKTK-NRGFAFVEYESHRAAAMARRKLLP-GRIQLWGHP-IAVDWAEPEVEVDEDTMSSV
-------------KILYVRNLMLSTS----------------------EEMIEKEFNN-IKPG-----------------
--------------------AVERVKKIRDYAFVHFSNREDAVE--AMKALHG---KVLDGS-----PIEVTLAKPVDKD
SYVRYTRGTGGR--GTMLQGEYT---------------------YSLGHVYDPT-T------TYLGAPVFYTPQAYTA-I
PSLHFPATKGHLGNRAIIRAPSVR--------GAAGV-RGLGG-RGYLAYTG----LGR------GYQVKGDKR-EDKLY
DLLPGMELT------------------------PMNPVTLKPQ---GIKL-----APQILEEICQKNNWGQPVYQLHSAI
GQDQRQLFLYKISIPALASQ-------------------NPAIHPFTPPKLS---AYVDEAKTYAAEYTLQTLGI-----
--------------------------------------------PTDGADA----PTTAAAAAAASV--------QDMP-
------SLMQLH---LCLQPSSSKQ---------------------------------
>Gallus_gallus_A1CF
--------------------------------------------------------------------------------
--------------------------------------------------MESNHK------------------------
-----------SGDGLTG-----------------------------TQKEAALRALIQRTGYNLIQENGQRKYGGPPPG
W---DGPPPERGC-----EIFIGKLPRDLF-EDELIPLCEKIGKIYEMRMMMDFNG-NNRGYAFVTFSNKQEARNAIKQL
--------------------------------------NNYEIR-NGRLLGVCASVDNCRLFVGGIPKTKKREEILAEMK
KVT----DGVVDVIVYPSAADKTK-NRGFAFVEYESHRAAAMARRKLLP-GRIQLWGHP-IAVDWAEPEVEVDEDTMSSV
-------------KILYVRNLMLSTT----------------------EETIEKEFNN-IKQG-----------------
--------------------AVERVKKIRDYAFVHFNKREDAVH--AMKALNG---KVLDGS-----PIEVTLAKPVDKD
SYVRYTRGTGGR--GAVLQGEYT---------------------YAFGHVYDPA-A------TYLGAPVFYAPQAYAA-I
PNFHFPATKG-LGSRSIIRPPSIR--------GAAGV-RGLGG-RGYLVYTG----LGR------GYQLKGEKRGEDKLY
DLLPGMELT------------------------PMNHVTLKPQ---GVKL-----APQILEEICQKNNWGQPVYQLHSAI
GQDQRQLFLYKITIPALASQ-------------------NPTIHPFTPPKLS---AYIDEAKTYAAEYTLQTLGI-----
--------------------------------------------PTEGAEV-------PPAAPAFP--------GYTIAN
AA-TTVTATQLK---QAVTMGQDLATYAAYEAYPAFA-VAAR-SDGYGAF--------
>Anolis_carolinensis_A1CF
--------------------------------------------------------------------------------
--------------------------------------------------MESNQK------------------------
-----------SGDGLAG-----------------------------TQKEAALHTISQRTGYKLYQENGQRKYGGPPPG
W---DGPPPERGC-----EIFIGKLPRDLF-EDELIPLCEKIGKIYEMRMMMDFNG-NNRGYAFVTFSNKQEARNAIRQL
--------------------------------------NNYEIR-NGRLLGVCASVDNCRLFVGGIPKTKKREEILAEIK
KVT----DGVVDVIVYPSAADKAK-NRGFAFVEYGSHRAAAMARRKLLP-GRIQLWGHP-IAVDWAEPEVEVDEDTMSAV
-------------KILYVRNLMLSTT----------------------EETIEKEFSS-IKPG-----------------
--------------------SVERVKKIRDYAFVHFNNREDAVE--AMKVLNG---KMVDGS-----PIKVTLAKPVDKD
SYVRYTRGTGGR--GGAVLPEYT---------------------YTFGPVYDPA-A------AYLGTPVFYAPQAYAA-I
PNLHFPAAKGHLANRATIRPPSIR--------GAAGV-RGLGG-RGYLANPA----LGR------GYQLKGEKREEEKLY
DLLPGMELT------------------------PMNPISLKPQ---GIKL-----APQILEEICQKNNWGQPVYQLHSAV
GQDQRQLFLYKITIPALASQ-------------------NPTMHPFTPPKLS---PYVDEAKTYAAEYTLQTLGI-----
--------------------------------------------PTESTET-------PTATASFPG---------YIAS
TA-ATVAATQLK---QAVTLGQDLAAYAAYEAYPAFA-VATR-SDGYGAF--------
>Xenopus_tropicalis_A1CF
--------------------------------------------------------------------------------
--------------------------------------------------MESNQK------------------------
-----------SGEGMAG-----------------------------TQKEAALRALIQRTGYSLTQENGQRRYGGPPPG
W---DGPPPERGC-----EIFIGKLPRDLF-EDELIPLCEKTGKVYEMRMMMDFNG-NNRGYAFVTFTNRQDARDAIKQL
--------------------------------------NNYEIR-NGRLLGVCASVDNCRLFVGGIPKTKRREEILVEMR
KVT----DGVLDVIVYPSAADKSK-NRGFAFVEYESHRAAAMARRKLLP-GRIQLWGHP-IAVDWAEPEVEVDEDTMSSV
-------------KILYVRNLMLTTA----------------------EETIEKEFSN-VKPD-----------------
--------------------ARRLKATHMPCTRCHFQRPVTVTR--ELCCIGA---KIIDGS-----PIEVTLAKPVDKE
SYVRYTRGTGGR--GAAIQGEYA---------------------YTIGHVYDPT-T------AYLGAPVFYAPPAYTAAI
PSIQFPPAKGYVSNRSLVRPPSVREIYMSVPVGAAGV-RGLGG-RGYLAYTG----LGRG---YAGFQMKGDKRADDKLY
DILPGMELT------------------------PMTTVALKPQ---GIKL-----GPQILEEICQKNNWGQPVYQLHSAI
GPDQRQLFLYKVTIPALASQ-------------------NPTIHPFTPPKLC---ISVDEAKTYAADYTLQTLGI-----
--------------------------------------------PTETAEH----------PTAFAG--------YTIAN
TP-AAVAATQLK---QAVALGQDIAAYATYEAYPAFA-VAAR-GDGYGAF--------
>Danio_rerio_A1CF_b
--------------------------------------------------------------------------------
--------------------------------------------------METNQK------------------------
-----------CGDGLTG-----------------------------TQKEAALRALIQRTGYHIHQENGQRRYGGPPPG
W---EGSPPERGS-----EIFVGKLPRDLF-EDELVPLCEKFGKIYEVRMMMDFNG-NNRGYAFVTFSTKQEAKNAMKQL
--------------------------------------NNYEIR-NGRLLGVCASVDNCRLFVGGIPKTKKREEILAEMK
KVT----DGVLDVIVYPSAADKAK-NRGFAFVEYETHRAAAMARRKLLP-GRIQLWGHP-IAVDWAEPEVEVDEDTMATV
-------------KILYVRNLMLPTT----------------------EETIEKEFNS-IKPG-----------------
--------------------AVERVKKIRDYAFVHFSQREDAIN--AMNALNG---KVIDGS-----PIEVTLAKPVDKD
SYVRYTRGTGGRG-GTVLQGDYA---------------------YTVGQMYDPS-A------AYLGAPIFYAPHAYATIP
NQFRFPSTKGQMSTRGLVRTPSVR------AVGAAGV-RGLGG-RGYLAYAG----VGR---GCGTYQLKTDKRPDDKLY
DLLPGMELT------------------------PMNPVTLKPQ---GIKH-----APQILEDICQKNNWGQPVYQLHSAI
GPDQRQLFLYKVTIPALATQ-------------------YPNIHPFTPAKLC---ASMDEAKLHAAEHTLQILGV-----
--------------------------------------------QTEGADAS----AAAAVAAAFPG--------YAIAS
TT-----GTQLK---QAVSLGQDLTAYATYEGYPAFA-VAAR-GDGYGVF--------
>Takifugu_rubripes_A1CF_a
--------------------------------------------------------------------------------
--------------------------------------------------MEANQNA-----------------------
-----------SGDELTG-----------------------------TQKEVQLRALTQRTGYQLRQENGQRRYGGPPPD
W---NGPPPERGS-----EIFVGKLPRDLF-EDELVPLCEKFGKIYEVRMMMDFSG-NNRGYAFVTFSNKQEAKAAMKQL
--------------------------------------NNYEIR-NGRLLGVCASVDNCRLFVGGIPKTKKREEIMCEMR
KVT----DGVLDVIVYPSAADKSK-NRGFAFVEYESHRAAAMARRKLLP-GRIQLWGHA-IAVDWAEPEVEVDEDTMATV
-------------KILYVRNLMLQTT----------------------EETIEKEFNS-LKQG-----------------
--------------------AVERVKKIRDYAFVHFTQREDAIH--AMNALNG---KVVDGS-----PIEVTLAKPVDKD
SYVRYTRGTGGRG-GS-LQTDYAT--------------------YSVGQMYDPS-T------AYLGAPMFYAPQTYAAMP
GQFRFPLAKAHIGGRGLIRPPSVREIYMTVPVGAAGV-RGLGG-RGYLAYTTGLGAVGRCGSSGASY-LKVDKQAEEKLY
ELLPGMELT------------------------PMSTAAMNLKAAAAIKP-----APQVLEELCQKNNWGQPVYQLHSAI
GPDQRQLFLYKITIPALATQ-------------------YPNVHPFTPTKLC---AVVEEAKVHAAEHTLQTLGL-----
--------------------------------------------LTEGASDAGCATTSAVASVAFPG--------YALVS
PA-SSAVASQLK---QAVSLGQDMTAYATYDGYPAFA-VAARHGDRYGVY--------
>Tetraodon_nigroviridis_A1CF
--------------------------------------------------------------------------------
--------------------------------------------------MESNQNA-----------------------
-----------SGDELTG-----------------------------TQKEAQLRALTQRTGYQLRQENGQRRYGGPPPD
W---NGPPPERGS-----EIFVGKLPRDLF-EDELVPLCEKFGQIYEVRMMMDFSG-NNRGYAFVTFSNKQEAKAAMKQL
--------------------------------------NNYEIR-TGRLLGVCASVDNCRLFVGGIPKTKKREEIMCEMR
KVT----EGVVDVIVYPSAADKSK-NRGFAFVEYESHRAAAMARRKLLP-GRIQLWGHA-IAVDWAEPEVEVDEDTMATV
-------------KILYVRNLMLQTT----------------------EETIEKEFNS-LKEGTG---------------
--------------------AVERVKKIRDYAFVHFAQREDAIH--AMKELNG---KVVDGS-----PIEVTLAKPVDKD
SYVRYTRGTGGRG-GS-LQTDYAT--------------------YSVGQVYDPS-A------AYLGAPMFYAPQTYATMP
GQFRFPLAKTHIGGRGLIRPPSVREIYMTVPVGAAGV-RGLGG-RGYLAYASGVGALGRGGSSGASYNMKVDKQGEEKLY
ELLPGMELT------------------------PMSTAAMNLK-AAAIKP-----APQVLEELCQKNNWGQPVYQLHSAI
GPDQRQLFLYKITIPALATQ-------------------YPNVHPFTPTKLC---AAVEEAKVHAAEHTLQTLGL-----
--------------------------------------------LTEGAGDAGCATAPAVAPVAFPG--------YTLVS
PA-SSAMASQLK---QAMTLGQDLTAYATYDGYPAFA-VAARHSDRYGVY--------
>Gasterosteus_aculeatus_A1CF_a
--------------------------------------------------------------------------------
--------------------------------------------------MEPNQKA-----------------------
-----------GGDGLAG-----------------------------MQKEAALRALMQRTGYQLQQENGQRRS------
---------ERGS-----EIFVGKLPRDLF-EDELVPLCEKYGTIYEVRMMMDFSG-NNRGYAFVTFGTKQEAKAAMKQL
--------------------------------------NNYEIR-NGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMR
KVT----DGVVDVIVYPSAADKSK-NRGFAFVEYESHRAAAMARRKLLP-GRIQLWGHA-IAVDWAEPEVEVDEDTMATV
-------------KILYVRNLMLQTT----------------------EETIEKEFNG-IRPG-----------------
--------------------SVERVKKIRDYAFVHFAQREDAVN--AMGALNG---KLVDGS-----PIEVTLAKPVDKD
SYVRYTRGTGGRG-ASLLQPDYAA--------------------YTLGQVYDPS-A------AYLGPPVFYAPQAYAAVP
GQFRFPAAKAHVGGRGLIRTPSVREIYMTVPVGAAGV-RGLGG-RGYLAYAAGIGAGG-----GASYSLKADKQVEEKLY
DLLPGMELT------------------------PMNPGAMNLK-A-AAKP-----ATQVLEELCQKNNWGQPVYQLHSAI
GPDQRQLFLYKITIPALATQ-------------------YPNVHPFTPAKLC---AAVEEAKVHAAEHTLQTLGL-----
--------------------------------------------QTEVAADASCATAATVASVTFPG--------YALAS
PG-ASAVVSQLK---QAVSLGQDLTAYTTYEGYPAFA-VAARHTDGYGVF--------
>Oryzias_latipes_A1CF_a
--------------------------------------------------------------------------------
--------------------------------------------------MESNQKP-----------------------
-----------SGDALAG-----------------------------MQKEAALRALIQRTGYQLQQENGQRRYGGPPPG
W---DGPHPERGS-----EIFVGKLPRDLF-EDELVPLCEKFGKIYEVRMMMDFNG-NNRGYAFVTFSNKQEAKTAMKQL
--------------------------------------NNYEIR-NGRLLGVCASVDNCRLFVGGIPKIKKRDEILTEMK
KVT----DGVVDVIVYPSAADKSK-NRGFAFVEYESHRAAAMARRKLLP-GRIQLWGYP-IAVDWAEPEVEVDDDTMATV
-------------KILYVRNLMLQTT----------------------EETIEREFNS-LKPG-----------------
--------------------AVERVKKIRDYAFVHFCQREDAIN--AMNALNG---KLVEGS-----PIEVTLAKPVDKD
SYVRYTRGTGGRG-SSLLQTDYTA--------------------YTLGQVYDPS-A------AYLGAPVFYAPQAYTALP
NQIRFPAAKAPVGGRGLIRSPSVREIYMTVPVGAAGV-RGLGG-RGYLAYSTGAGALGR-GSGGTSCGLKVCKQAEEKLY
DLLPGMELT------------------------PMNPAAMNLK-ANALKP-----ATQVLEELCQKNNWGQPVYQLHSAI
SPEQRQLFLYKITIPALASQ-------------------YPNLHPFTPAKLC---AAVEEAKVHAAEYTLQTLGL-----
--------------------------------------------QSDGTADA---TAAAMTSVAFPG--------YTLAS
PVSSAAVASQLK---EAASLGQELTAYAAYEGYPAFA-VAARHTDGYGVF--------
>Ciona_intestinalis_A1CF
--------------------------------------------------------------------------------
-------------------------------------------------MIANNQQSVSES-------------------
----------SNPEPLCNN----------------------------PAKEAALHALCQKTGYTIKQENGQRKYGGPPPH
W---NDVIPGKGC-----EVFVGKLPRDLY-EDELVPVLEKCGRIYELRLMMDFNG-NNRGFAFVKYCAASEARAALKDL
--------------------------------------NNFEIR-KGRLLGVCKSVDNCRLFVGGIPKTKQKEEILIEMK
KVT----EGVCDVIVYPSAADKQK-NRGFAFVEYQDHHTAAMARRKLMH-TRPQIWGHP-IAVDWAEPEVEVDDDIMATV
-------------KILYVRNLMLNTT----------------------EEQLEAEFSALVPSG-----------------
--------------------SIERVKKIRDYGFVHFNTRENAIK--CLKQLNG---KILDGS-----PMEVTLAKPVDRE
TYVRYTRAANRV-VETQEPLTIPG---------------------YVATTYDPRFDPASAAYSYAGGPIYY--GVPYG--
ATTIPTLASSPRFAVPPLRGGVPQVPGMVTQIGAAGVPLGIPG--ATTGIAGA---QGR------GISLRGRNR-AAEKY
DLMPDMVLT------------------------PTNPLSLKPS--QLQKS-----PIQLLEEYCMKMSLGNPDYKLHSAD
GQNGRQLFLYRVEIPGLSSSQSQQDTSYNPN----QSAQAKPN-QFTPTKLC---TSLDVAKEIAASHVLDSLSG-----
--------------------------------------------DDVTTDDVKPDVEQVYVTDNIPT----------VGT
GINGDVNGYAMY---NGAVTDSDYSSFQLYNSTVTYPGIATTATDAYGPY--------
>Ciona_savignyi_A1CF
--------------------------------------------------------------------------------
--------------------------------------------------SQANHKSVNDS-------------------
----------SNPEPLCIN----------------------------PAKEAALHALCQKTGYTIKQENGQRKYGGPPPH
W---NDAIPGKGC-----EVFVGKLPRDLY-EDELVPVLERCGRIYELRLMMDFNG-NNRGFAFVKYCACSEARAALKDL
--------------------------------------NNFEIR-KGRLLGVCKSVDNCRLFVGGIPKTKQKDEILIEMK
KVT----EGVVNVIVYPSAADKQK-NRGFAFVEYQDHHTAAMARRKLMH-TRPQIWGHP-IAVDWAEPEVEVDEDVMATV
-------------KILYVRNLMLNTT----------------------EEQLEAEFSALVPAG-----------------
--------------------SIERVKKIRDYGFVHFNTRENAIT--CLKKLNG---KLLDGS-----PMEVSLAKPVDRE
TYVRYTRAANRVPLDSQEPLAIPG---------------------FVPATYDPSFK---VVFLYAGGPIYYTTGVPYG--
AATIPTLTATPRFAMPSIRGGVTQVPGMVTQIGAAGVPLGIPG--ATTGISGG---QGR------GPVQ-------PEKY
DLLPDMVLT------------------------PTNPLSLKPS--QLQKS-----PIQLLEEYCMKMSLGNPEYKLHSAE
GQNGRQLFLYRVDIPGFSS----------------QSVSAKPSSQFTPTKLC---ISLDVAKEIAASHVLENLS------
-----------------------------------------------IADD-----------------------------
----------------------------------------------------------
>Nematostella_vectensis_A1CF
--------------------------------------------------------------------------------
--------------------------------------------------ME----------ESG--------------P
EQV---------TDGVTG-----------------------------TPKEAALRALMERTKFPIRQCNGQRRYG-PPPG
W---DRPIPPRGC-----EVFVGKIPRDLY-EDELVPVFETAGPIYEVRLMMDFNG-QNRGYAFVVYTSKDDAKRCVKTL
--------------------------------------NNYEIR-KGKCIGVCSSVDNCRLFVGGIPKKVKKDEIMAEVS
KVT----DNVVDVIVYPSAQDKTK-NRGFAFVEYISHRDAAMARRKLMT-GKIQLWGHQ-IAVDWAEPEQEVDQEIMDQV
-------------KVLYARNLLLSTT----------------------EETIEQAFSK---FG-----------------
--------------------EVERVKKIKDYCFIHFRTKEQARD--AMEAMNET---ELDGN-----EIEVTLAKPVDKD
HR---------------------------------------------------------------------SPLLFRG--
----------YYGTPSMRPG----------------------------------------------------------FY
G---------------------------------------------DYKK-----SQEILEDVCQKNQWGSPVYTLHSTL
GPQEVQLFLYKVSIPGLAT-------------------------QYQPPKLC---RTVEEAKNYAAEHTLQQLG------
--------------------------------------------------------------------------------
-ISLEGMSR-------------------------------------------------
>Homo_sapiens_HNRNPR
-----------------------------------------------------------------MANQVNGNAVQLKEE
EEPMDTSSVT------HTEHYKTLIEAGLPQKVAERLDEIFQTGLVAYVDLDERAIDALREFNEEGALSVLQQFKESDLS
HVQNKSAFLCGVMKTYRQ--REKQGSKVQ--------------ESTKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPD
SVY-SGVQPGIGT-----EVFVGKIPRDLY-EDELVPLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLC
--------------------------------------DSYEIR-PGKHLGVCISVANNRLFVGSIPKNKTKENILEEFS
KVTG-LTEGLVDVILYHQPDDKKK-NRGFCFLEYEDHKSAAQARRRLMS-GKVKVWGNV-VTVEWADPVEEPDPEVMAK-
------------VKVLFVRNLATTVT----------------------EEILEKSFSEFGKLE-----------------
-----------------------RVKKLKDYAFVHFEDRGAAVK--AMDEMNG---KEIEGE-----EIEIVLAKPPDKK
RKERQAARQASRS--------------------------------------------------TAYEDYYYHPPP-RMPP
PIRGRGRGGG----RGGYGYPPDYYGYEDYYDDY----------------------------------------YGYDYH
DYRGGYEDPYY----------------------------------------------GYDD-GYAVRGRGGG-RGGRGAP
PPPRGRGAP----------------------------------PPRGRAGYSQRGAPLGPPRGSRG-----GRGGP----
----------------------------------------------AQQQRGRGSRGSRGNRGGNVGGKRKADGYNQ--P
DSKRRQTNNQQ-NWGSQPIAQQPLQQGGDYSGNY--GYNNDNQEFYQDTYGQ-QWK--
>Mus_musculus_HNRNPR
-----------------------------------------------------------------MANQVNGNAVQLKEE
EEPMDTSSVT------HTEHYKTLIEAGLPQKVAERLDEIFQTGLVAYVDLDERAIDALREFNEEGALSVLQQFKESDLS
HVQNKSAFLCGVMKTYRQ--REKQGSKVQ--------------ESTKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPD
SVY-SGVQPGIGT-----EVFVGKIPRDLY-EDELVPLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLC
--------------------------------------DSYEIR-PGKHLGVCISVANNRLFVGSIPKNKTKENILEEFS
KVT----EGLVDVILYHQPDDKKK-NRGFCFLEYEDHKSAAQARRRLMS-GKVKVWGNV-VTVEWADPVEEPDPEVMAK-
------------VKVLFVRNLATTVT----------------------EEILEKSFSEFGKLE-----------------
-----------------------RVKKLKDYAFVHFEDRGAAVK--AMDEMNG---KEIEGE-----EIEIVLAKPPDKK
RKERQAARQASRS--------------------------------------------------TAYEDYYYHPPP-RMPP
PMRGRGRGG-----RGGYGYPPDYYGYEDYYDDY----------------------------------------YGYDYH
DYRGGYEDPYY----------------------------------------------GYDD-GYAVRGRGGG-RGGRGAP
PPPRGRGAP----------------------------------PPRGRAGYSQRGAPLGPPRGSRG-----GRGGP----
----------------------------------------------AQQQRGRGSRGARGNRGGNVGGKRKADGYNQ--P
DSKRRQTNNQQ-NWGSQPIAQQPLQQGGDYSGNY--GYNNDNQEFYQDTYGQ-QWK--
>Canis_familiaris_HNRNPR
-----------------------------------------------------------------MANQVNGNAVQLKEE
EEPMDTSSVT------HTEHYKTLIEAGLPQKVAERLDEIFQTGLVAYVDLDERAIDALREFNEEGALSVLQQFKESDLS
HVQNKSAFLCGVMKTYRQ--REKQGSKVQ--------------ESTKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPD
SVY-SGVQPG