>Homo_sapiens_PPARGC1A
--------------------------------------------------------------------------------
-------------------------------------------------MAWDMCNQDSESVWSDIECAALVG-------
-EDQPLCPDLPELDLS--ELDVNDLDTDSFLGGLKWCSD-----------QSEIISNQYNN--EPSNIFEKIDEENEANL
LAVLTETLDSLPVD------------------------------EDGLPSFDALTDGDVTTDNEASPSSMPDGTPP----
--------------------------------------------------------------------------------
---PQEAEEPSLLKKLLLAPANTQLSYNECSGLSTQNHAN----------------------------------------
---------------HNHRIRTNPAIVKTENSWSNKAKS-----------------------------------------
-------------------ICQQQKPQRRPCSELLKYLTT----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------NDDPP-HTKPTENRNSSRD-------------------------------------------------------
---------KCTSKKKSHTQSQSQ--------HLQAKPTTLSLPLTPESPNDPKGSPFEN--------------------
--------------------------------------------------------------------------------
-------------------KTIERTLSVELSGTAGLTPPTTPPHKANQDNPFRASPKLKSSCKTVVPPPSKKPRYSES--
------SGTQGNNSTK----------------------KGPEQSELYAQLSKSS--------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------VLTGGHEERKT----KRPSLR-------
--------------------------------------------------------------------------------
--------------------------------LFGDHDYCQSINS-----------------------------------
--------KTEILINISQELQDSRQLENKDVSSD-WQGQICSSTDS-DQCYLRETLEASKQVSPCS------TRKQLQDQ
EIRAELNKHFG------HPSQAVFDDEADKTGELRD-SDFSNEQFSKLPMFINS--------------------------
-------GLAMDGLF-----------------------------------------------------------------
--------------------------------------------------------------------------------
------------------DDSEDESDKLS------------------------------YPWDGTQSYSLFNV---SPSC
S----------------------------------------------------------------SFNSPCRDSVSPPKS
LFSQRP-------------------------------------------QRMRSR---SRSFS--------RHRSCSRSP
YSRSRSRSPGSRSSSRSCYYYESSHYR-------------------------------HRTHRNSPLYVRSRSRSPYSRR
P---------------------RYDSYEEYQHERLKREEYRREYE----------------------------KRESERA
KQRERQRQKAIEERRVIYVGKIRPDTTRTELRDRFEVFGEIEECTVNLRDD-----------------------------
-------GDSYGFI-------------------------------------------------TYRYTCDAFAALENGYT
LRRSNETDFELYFCGRKQFFKSNYADLDSNSDDFDP------------------------------------------AS
TKSKYDSLDFDSLLKEAQRSLRR---------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------
>Pan_troglodytes_PPARGC1A
--------------------------------------------------------------------------------
-------------------------------------------------MAWDMCNQDSESVWSDIECAALVG-------
-EDQPLCPDLPELDLS--ELDVNDLDTDSFLGGLKWCSD-----------QSEIISNQYNN--EPSNIFEKIDEENEANL
LAVLTETLDSLPVD------------------------------EDGLPSFDALTDGDVTTDNEASPSSMPDGTPP----
--------------------------------------------------------------------------------
---PQEAEEPSLLKKLLLAPANTQLSYNECSGLSTQNHAN----------------------------------------
---------------HNHRIRTNPAIVKTENSWSNKAKS-----------------------------------------
-------------------ICQQQKPQRRPCSELLKYLTT----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------NDDPP-HTKPTENRNSSRD-------------------------------------------------------
---------KCISKKKSHTQSQSQ--------HLQAKPTTLSLPLTPESPNDPKGSPFEN--------------------
--------------------------------------------------------------------------------
-------------------KTIERTLSVELSGTAGLTPPTTPPHKANQDNPFRASPKLKSSCKTVVPPPSKKPRYSES--
------SGTQGNNSTK----------------------KGPEQSELYAQLSKSS--------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------VLTGGHEERKT----KRPSLR-------
--------------------------------------------------------------------------------
--------------------------------LFGDHDYCQSINS-----------------------------------
--------KTEILINISQELQDSRQLENKDVSSD-WQGQICSSTDS-DQCYLRETLEASKQVSPCS------TRKQLQDQ
EIRAELNKHFG------HPSQAVFDDEADKTSELRD-SDFSNEQFSKLPMFINS--------------------------
-------GLAMDGLF-----------------------------------------------------------------
--------------------------------------------------------------------------------
------------------DDSEDESDKLS------------------------------YPWDGTQSYSLFNV---SPSC
S----------------------------------------------------------------SFNSPCRDSVSPPKS
LFSQRP-------------------------------------------QRMRSR---SRSFS--------RHRSCSRSP
YSRSRSRSPGSRSSSRSCYYYESSHYR-------------------------------HRTHRNSPLYVRSRSRSPYSRR
P---------------------RYDSYEEYQHERLKREEYRREYE----------------------------KRESERA
KQRERQRQKAID--------------------------------------------------------------------
---------SYGFI-------------------------------------------------TYRYTCDAFAALENGYT
LRRSNETDFELYFCGRKQFFKSNYADLDSNSDDFDP------------------------------------------AS
TKSKYDSLDFDSLLKEAQRSLRR---------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------
>Pongo_abelii_PPARGC1A
--------------------------------------------------------------------------------
-------------------------------------------------MAWDMCNQDSESVWSDIECAALVG-------
-EDQPLCPDLPELDLS--ELDVNDLDTDSFLGGLKWCSD-----------QSEIISNQYNN--EPSNIFEKIDEENEANL
LAVLTETLDSLPVD------------------------------EDGLPSFDALTDGDVTTDNEASPSSMPDGTPP----
--------------------------------------------------------------------------------
---PQEAEEPSLLKKLLLAPANTQLSYNECSGLSTQNHAN----------------------------------------
---------------HNHRIRTNPAIVKTENSWSNKAKS-----------------------------------------
-------------------ICQQQKPQRRPCSELLKYLTT----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------NDDPP-HTKPTENRNSSRD-------------------------------------------------------
---------KCTSKKKSHTQSQSQ--------HLQAKPTTLSLPLTPESPNDPKGSPFEN--------------------
--------------------------------------------------------------------------------
-------------------KTIERTLSVELSGTAGLTPPTTPPHKANQDNPFRASPKLKSSCKTVVPPPSKKPRYSES--
------SGTQGNNSTK----------------------KGPEQSELYAQLSKSS--------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------VLTGGHEERKT----KRPSLR-------
--------------------------------------------------------------------------------
--------------------------------LFGDHDYCQSINS-----------------------------------
--------KTEILINISQELQDSRQLENKDVSSD-WQGQICSSTDS-DQCYLRETLEASKQVSPCS------TRKQLQDQ
EIRAELNKHFG------HPSQAVFDDEADKTSELRD-SDFSNEQFSKLPMFINS--------------------------
-------GLAMDGLF-----------------------------------------------------------------
--------------------------------------------------------------------------------
------------------DDSEDESDKLS------------------------------YPWDGTQSYSLFNV---SPSC
S----------------------------------------------------------------SFNSPCRDSVSPPKS
LFSQRP-------------------------------------------QRMRSR---SRSFS--------RHRSCSRSP
YSRSRSRSPGSRSSSRSCYYYESSHYR-------------------------------HRTHRNSPLYVRSRSRSPYSRR
P---------------------RYDSYEEYQHERLKREEYRREYE----------------------------KRESERA
KQRERQRQKAIEERRVIYVGKIRPDTTRTELRDRFEVFGEIEECTVNLRDD-----------------------------
-------GDSYGFI-------------------------------------------------TYRYTCDAFAALENGYT
LRRSNETDFELYFCGRKQFFKSNYADLDSNSDDFDP------------------------------------------AS
TKSKYDSLDFDSLLKEAQRSLRR---------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------
>Macaca_mulatta_PPARGC1A
--------------------------------------------------------------------------------
-------------------------------------------------MAWDMCNQDSESVWSDIECAALVG-------
-EDQPLCPDLPELDLS--ELDVNDLDTDSFLGGLKWCSD-----------QSEIISNQYNN--EPSNIFEKIDEENEANL
LAVLTETLDSLPVD------------------------------EDGLPSFDALTDGDVTTDNEASPSSMPDGTPP----
--------------------------------------------------------------------------------
---PQEAEEPSLLKKLLLAPANTQLSYNECSGLSTQNHAN----------------------------------------
---------------HNHRIRTNPAIVKTENSWSNKAKS-----------------------------------------
-------------------ICQQQKPQRRPCSELLKYLTT----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------NDDPP-HTKPTENRNSSRD-------------------------------------------------------
---------KCTSKKKSHTQSQSQ--------HLQAKPTTLSLPLTPESPNDPKGSPFEN--------------------
--------------------------------------------------------------------------------
-------------------KTIERTLSVELSGTAGLTPPTTPPHKANQDNPFRASPKPKSSCKTVVPPPSKKPRYSES--
------SGTQGNNSTK----------------------KGPEQSELYAQLSKST--------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------VLTGGHEERKT----KRHSLR-------
--------------------------------------------------------------------------------
--------------------------------LFGDHDYCQSINS-----------------------------------
--------KTEILIHISQELQDSRQLENKDVSSD-WQGQICSSTDS-DQCYLRETSEASKQVSPCS------TRKQLQDQ
EIRAELNKHFG------HPSQAVFDDEADKTSELRD-SDFSNEQFSKLPMFINS--------------------------
-------GLAMDGLF-----------------------------------------------------------------
--------------------------------------------------------------------------------
------------------DDSEDESDKLS------------------------------YPWDGTQSYSLFNV---SPSC
S----------------------------------------------------------------SFNSPCRDSVSPPKS
LFSQRP-------------------------------------------QRMRSR---SRSFS--------RHRSCSRSP
YSRSRSRSPGSRSSSRSCYYYESSHYR-------------------------------HRTHRNSPLYVRSRSRSPYSRR
P---------------------RYDSYEEYQHERLKREEYRREYE----------------------------KRESERA
KQRERQRQKAIEERRVIYVGKIRPDTTRTELRDRFEVFGEIEECTVNLRDD-----------------------------
-------GDSYGFI-------------------------------------------------TYRYTCDAFAALENGYT
LRRSNETDFELYFCGRKQFFKSNYADLDSNSDDFDP------------------------------------------AS
TKSKYDSLDFDSLLKEAQRSLRR---------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------
>Canis_familiaris_PPARGC1A
--------------------------------------------------------------------------------
-------------------------------------------------MAWDMCNQDS--VWSDIECAALVG-------
-EDQPLCPDLPELDLS--ELDVNDLDTDSFLGGLKWCSD-----------QSEIISNQYNN--EPSNIFEKIDEENEANL
LAVLTETLDSLPVD------------------------------EDGLPSFDALTDGDVTTENEASPSSVPDGTPP----
--------------------------------------------------------------------------------
---PQEAEEPSLLKKLLLAPANTQLSYNECSGLSTQNHAN----------------------------------------
---------------HNHRIRTNPAVVKTENSWSNKAKS-----------------------------------------
-------------------ICQQQKPQRRPCSELLKYLTT----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------NDDPP-HTKPTENRNSSRD-------------------------------------------------------
---------KCTSKKKSHTQSQSQ--------HLQAKPTTLSLPLTPESPNDPKGSPFEN--------------------
--------------------------------------------------------------------------------
-------------------KTIERTLSVELSGTAGLTPPTTPPHKANQDNPFRTSPKLKSSCKTVVPPPSKKPRYSEP--
------SGTQGNTSTK----------------------KGPEQSELYAQLSKTS--------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------VLTSGHEERKA----KRPSLR-------
--------------------------------------------------------------------------------
--------------------------------LFGDHDYCQSINS-----------------------------------
--------KTEILINISQELQDSRQLEYKDASSD-WQGQICSSTDS-DQCYLRETSGAGKQVSPCS------TRKQLQDQ
EIRAELNKHFG------HPSQAVFDDEADKTSELRN-SDFSNEQFSKLPMFINS--------------------------
-------GLAMDGLF-----------------------------------------------------------------
--------------------------------------------------------------------------------
------------------DDSEDESDKLN------------------------------YPWDGTQSYSLFDV---SPSC
S----------------------------------------------------------------SFNSPCRDSVSPPKS
LFAQRP-------------------------------------------QRMRSR---SRSFS--------RHRSCSRSP
YSRSRSRSPGSRSSSRSCYHYESSHCR-------------------------------HRAHRNSPLCARSRSRSPYSRR
P---------------------RYDSYEEYQHERLKREEYRREYE----------------------------KRESERA
KQRERQRQKAIEERRVIYVGKIRPDTTRTELRDRFEVFGEIEECTVNLRDD-----------------------------
-------GDSYGFI-------------------------------------------------TYRYTCDAFAALENGYT
LRRSNETDFELYFCGRKQFFKSNYADLDSNSDDFDP------------------------------------------AS
TKSKYDSLDFDSLLKEAQRSLRR---------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------
>Felis_catus_PPARGC1A
--------------------------------------------------------------------------------
-------------------------------------------------MAWDMCNQDS--VWSDIECAALVG-------
-EDQPLCPDLPELDLS--ELDVNDLDTDSFLGGLKWCSD-----------QSEIISNQYNN--EPSNIFEKIDEENEANL
LAVLTETLDSLPVD------------------------------EDGLPSFDALTDGDVTTENEASPSSMPDGTPP----
--------------------------------------------------------------------------------
---PQEAEETSLLKKLLLAPANTQLSYNECSGLSTQNHAN----------------------------------------
---------------HNHRIRTNPAVVKTENSWSNKARS-----------------------------------------
-------------------ICQQQKPQRRPCSELLKYLTT----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------NDDPP-HIKPTENRNSSRD-------------------------------------------------------
---------KCTSKKKSHTQSQSQ--------HLQAKPTTLSLPLTPESPNDPKGSPFEN--------------------
--------------------------------------------------------------------------------
-------------------KTIERTLSVELSGTAGLTPPTTPPHKANQDNPFRTSPKLKSSCKTVGPPPSKKPRYSEP--
------PGTQGNNSTK----------------------KGPEQSELYAQLSKTS--------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------VLTSGHEERKA----KRPSLR-------
--------------------------------------------------------------------------------
--------------------------------LFGDHDYCQSINS-----------------------------------
--------KTEILINISQELQDSRQLEYKDAPSD-WQGQICSSTDS-DQCYLRETPGAGKQVSPGS------TRKQLQDQ
EIRAELNKHFG------HPSQAVFDDEADKTSELRD-SDFSNEQFSKLPMFINS--------------------------
-------GLAMDGLF-----------------------------------------------------------------
--------------------------------------------------------------------------------
------------------DDSEDESDKLN------------------------------YPWDGTQSYSLFDV---SPSC
S----------------------------------------------------------------SFNSPCRDSVSPPKS
LFSQRP-------------------------------------------QRMRSR---SRSFS--------RHRSCSRSP
YSRSRSRSPGSRSSSRSCYYYESSHCR-------------------------------HRAHRNSPLCARSRSGSPYSRR
P---------------------RYDSYEEYQHERLKREEYRKEYE----------------------------KRESERA
KQRERQRQKAIEERRVIYVGKIRPDTTRTELRDRFEVFGEIEECTVNLRDD-----------------------------
-------GDSYGFI-------------------------------------------------TYRYTCDAFAALENGYT
LRRSNETDFELYFCGRKQFFKSNYADLDSNSDDFDP------------------------------------------AS
TKSKYDSLDFDSLLKEAQRSLRR---------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------
>Equus_caballus_PPARGC1A
--------------------------------------------------------------------------------
-------------------------------------------------MAWDMCNQDS--VWSDIECAALVG-------
-EDQPLCPDLPELDLS--ELDVNDLDTDGFLGGLKWCSD-----------QSEIISNQYNN--EPSNIFEKIDEENEANL
LAVLTETLDSLPVD------------------------------EDGLPSFDALTDGDVTTENEASPSSMPDGTPP----
--------------------------------------------------------------------------------
---PQEAEEPSLLKKLLLAPANTQLSYNECSGLSTQNHAN----------------------------------------
---------------HNHRIRTNPAVVKTENSWSNKAKS-----------------------------------------
-------------------ICQQQKPQRRPCSELLKYLTT----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------NDDPP-HTKPTENRNSSRD-------------------------------------------------------
---------KCTSKKKSHTQSQSQ--------HLQAKPTTLSLPLTPESPNDPKGSPFEN--------------------
--------------------------------------------------------------------------------
-------------------KTIERTLSVELSGTAGLTPPTTPPHKANQDNPFRASPKLKSSCKTVVPPPSKKPRYSEP--
------SGTQGNNSTK----------------------KGPEQSELYAQLSKSS--------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------VLTSGHEERKA----KRPSLR-------
--------------------------------------------------------------------------------
--------------------------------LFGDHDYCQSINS-----------------------------------
--------KTEILINISQELQDSRQLEYKDASSN-WQGQICSSTDS-DQCYLRETLEGSKQVSPCS------TRKQLQDQ
EIRAELNKHFG------HPSRAVFDDEADKTSELRD-SDFSNEQFSKLPMFINS--------------------------
-------GLAMDGLF-----------------------------------------------------------------
--------------------------------------------------------------------------------
------------------DDSEDESDKLN------------------------------YPWDGTQSYSLFDV---SPSC
S----------------------------------------------------------------SFNSPCRDSVSPPKS
LFSQRP-------------------------------------------QRMRSR---SRSFS--------RHRSCSRSP
YSRSRSRSPGSRSSSRSCYYHESSHCR-------------------------------HRTHRNSPLCARSRSRSPYSRR
P---------------------RYDSYEEYQHERLKREEYRKEYE----------------------------KRESERA
KQRERQRQKAIEERRVIYVGKIRPDTTRTELRDRFEVFGEIEECTVNLRDD-----------------------------
-------GDSYGFI-------------------------------------------------TYRYTCDAFAALENGYT
LRRSNETDFELYFCGRKQFFKSNYADLDSNSDDFDP------------------------------------------AS
TKSKYDSLDFDSLLKEAQRSLRR---------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------
>Loxodonta_africana_PPARGC1A
--------------------------------------------------------------------------------
-------------------------------------------------MAWDMCNQDS--VWSDIECAALVG-------
-EDQPLCPDLPELDLS--ELDVNDLDTDSFLGGLKWCSD-----------QSEIISNQYNN--EPSNIFEKIDEESEANL
LAVLTETLDSLPVD------------------------------EDGLPSFDALTDGDVTTDNDASPSSMPDGTPP----
--------------------------------------------------------------------------------
---PQEAEEPSLLKKLLLAPANTQLSYSECSGLSTQNHAN----------------------------------------
---------------HNHRIRTNPAVVKTETSWSNKAKS-----------------------------------------
-------------------ICQQQKPQRRPCSELLKYLTT----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------NDDPP-HTKPTENRNSHRD-------------------------------------------------------
---------KCTSKKKPHTQSQVS--------HLQAKPTTLSLPLTPESPNDPKGSPFEN--------------------
--------------------------------------------------------------------------------
-------------------KTIERTLSVELSGTAGLTPPTTPPHKANQDNPFRTSPKLKSSCKTVVPLPSKKPRHSES--
------SGTQGNNSTK----------------------KGPKQSELYAQLSKTS--------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------VLTSGHEERKT----KRPSLR-------
--------------------------------------------------------------------------------
--------------------------------LFGDHDYCQSINS-----------------------------------
--------KSEILINISQELQDSRKLEYKDASSD-WQGQICSSTDS-DQCYLRETLEASKQVSPGS------TRKQLQDQ
EIRAELNKHFG------HPSQAVFDDEANKTSELRD-SDFSNEQFSKLPMFINS--------------------------
-------GLAMDGMF-----------------------------------------------------------------
--------------------------------------------------------------------------------
------------------EDSEDESDKLS------------------------------YPWDGTQSYSLFDV---SPSC
S----------------------------------------------------------------SFNSPCRDSVSPPKS
LFSQRP-------------------------------------------QRMCSR---SRSFS--------RHRSCSRSP
YSRSRSRSPGSRSSSRSCHYCESSHCR-------------------------------HRTHRNPPLCGRSRSRSPCSRR
P---------------------RYDSYEEYQHERLKREEYRKEYE----------------------------KRESERA
KQRERQRQKAIEERRVIYVGKIGSDTTRTELRDRFEVFGEIEECTVNLRDD-----------------------------
-------GDSYGFI-------------------------------------------------TYRYTCDAFAALENGYT
LRRSNETDFELYFCGRKQFFKSNYADLDSNSDDFDP------------------------------------------AS
AKSKYDSLDFDSLLKEAQRSLRR---------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------
>Ornithorhynchus_anatinus_PPARGC1A
--------------------------------------------------------------------------------
-------------------------------------------------MAWDMCNQDS--VWSDIECAALVG-------
-EDQPLCPDLPELDLS--ELDVNDLDADSFLGGLKWYSD-----------QSEIISNQYSN--EPSNIFEKIDEENEANL
LAVLTETLDSIPVD------------------------------EDGLPSFDALTDGDVTNENDSSPSSMPDGTPP----
--------------------------------------------------------------------------------
---TQEAEEPSLLKKLLLAPANTQLSYNECCGLSTQNHAN----------------------------------------
---------------PNHRIRTIPAVVKTENSWSNKAKS-----------------------------------------
-------------------ICQQQKPQRRPCSELLKYLTT----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------NDDPP-QTKAAESRSSSQD-------------------------------------------------------
---------KCTSKKKPHLQPQTH--------HLQAKPTSLSLPLTPESPNDAKGSPFEN--------------------
--------------------------------------------------------------------------------
-------------------KNIERTLSVELSGTAGLTPPTTPPHKVNQDSPFRTSPKPKSSCKTVVP-PSKKPRFSES--
------SRTQGNNPNK----------------------KSPEQSELYAQLSKNS--------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------VLSSGHEERKS----KRPSLR-------
--------------------------------------------------------------------------------
--------------------------------LFGDHDYCQSLNA-----------------------------------
--------KAEIRINVPQELQDSRQLEYKDSSSG-WQWQICTSADQ-DQCSTRETSQESKQGAPRN------NRKQLQDQ
EIRAELNKHFG------HPSQAVFDDEADKTSELRD-SDFSNEQFSKLPMFINS--------------------------
-------GLAMDGLF-----------------------------------------------------------------
--------------------------------------------------------------------------------
------------------DDSEDENDKLC------------------------------YPWDGTQFYSLFDV---SPSC
S----------------------------------------------------------------SFNSPCRDSVSPPKS
LFSQRS-------------------------------------------QRILSR---SRSFS--------RHRSCSRSP
YSRSRSRSPSSRSSSRSCYYYEPSHCR-------------------------------PRAPRRSPLHARSRSRSPFSRR
P---------------------RYDSYEEYQHERLKREEYRKEYE----------------------------KRESERA
KQRDRQRQKAIEERRVIYVGKIRPDTTRTELRDRFEVFGEIEECTVNLRDD-----------------------------
-------GDSYGFI-------------------------------------------------TYRYTCDAFAALENGYT
LRRSNEPDFELYFCGRKQFFKSNYADLDSNSDDFDP------------------------------------------AS
TKSKYDSMDFDSLLREAQRSLRR---------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------
>Gallus_gallus_PPARGC1A
--------------------------------------------------------------------------------
-------------------------------------------------MAWDMCNQDS--VWSDIECAALVG-------
-EDQPLCPDLPELDLS--ELDVNDLDADSFLGGLKWYSD-----------QSEVISSQYSN--EPANIFEKIDEENEANL
LAVLTETLDSIPVD------------------------------EDGLPSFDALTDGDVTNEHDASPSPMPDGTPP----
--------------------------------------------------------------------------------
---PQEAEEPSLLKKLLLAPANTQLNYNECSGLSTQNHAN----------------------------------------
---------------TNHRIRTSPVVVKTENSWSNKAKS-----------------------------------------
-------------------ICQQQKPQRRPCSELLKYLTT----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------NDDPP-QTKPAENRNSSKE-------------------------------------------------------
---------KCTSKRKPHLQSQTN--------HLQAKPTSLSLPLTPESPNDPKGSPFEN--------------------
--------------------------------------------------------------------------------
-------------------KTIEQTLSVELSGTAGLTPPTTPPHKANQDNPFRTSPKPKSSCKTVAP-PSKKPRYSES--
------SGSQGNNPVK----------------------KGPEQTELYAQLSKTT--------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------ALSSGHEERKT----KRPSLR-------
--------------------------------------------------------------------------------
--------------------------------LFGDHDYCQSVNS-----------------------------------
--------KSEIHIKISQELQDSRQLEFKDSSPG-WQCQICSSLEQ-DQYFKKETLQTSKQGSQGN------NRKQLQDQ
EIRAELNKHFG------HPSQAVFDEEADKTGELRD-SDYSNEQFSKLPMFINS--------------------------
-------GLAMDGLF-----------------------------------------------------------------
--------------------------------------------------------------------------------
------------------DDSEDESDKLC------------------------------YPWDGTQAYSLFDV---SPSC
S----------------------------------------------------------------SFNSPCRDSVSPPKS
LFSQRS-------------------------------------------QRTRSR---SRSFP--------QRRSCSRSP
YSRSRSRSPCSRSSSRSCHCYESSHCR-------------------------------HRAHRSSPSRARSRSRSPYSRR
P---------------------RYDSYEEYQHERLKREEYRKEYE----------------------------KRESERA
KQRERQRQKAIEERRVIYVGKIRPDTTRKDLRDRFEVFGEIEECTVNLRDD-----------------------------
-------GDSYGFI-------------------------------------------------TYRYTCDAFAALENGYT
LRRSNEPDFELYFCGRKQFCKSNYADLDSNSDDFDP------------------------------------------AS
TKSKYDSMDFDSLLKEAQRSLRR---------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------
>Anolis_carolinensis_PPARGC1A
--------------------------------------------------------------------------------
-------------------------------------------------MAWDMCNQDS--VWSDIECAALVG-------
-EDQPLCPDLPELDLS--ELDVNDLDADSFLGGLKWYSD-----------QSEIISNQYAN--ESSNIFEKIDEENEANL
LAVLTETLDSIPVD------------------------------EDGLPSFDALTDGDVTNENDASPSPMPDGTPP----
--------------------------------------------------------------------------------
---AQEAEEPSLLKKLLLAPANIQLNYNECSGLSTHNHAN----------------------------------------
---------------ANHRIRTSPVVVKTENSWSNKTKS-----------------------------------------
-------------------ICQPQKPQRRQCSELLKYLTT----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------NDDPP-QTKPTENRNSSRD-------------------------------------------------------
---------KCTSKKKVLLHSQMH--------HLQAKPMSLSLPLTPESPNDPKGSPFEN--------------------
--------------------------------------------------------------------------------
-------------------KTIEQTLSVELSGTAGLTPPTTPPHKANQDNPFRTSPKPKSSCKTVMP-PSKKPRCNES--
------SSSQGHNLGR----------------------KGPEQSELYAQLSKTT--------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------VLSVSHEERKT----KRPGLR-------
--------------------------------------------------------------------------------
--------------------------------LFGDHDYCQSANS-----------------------------------
--------KTGIRINRSQEPQDSRQVDLNGGLPE-QWCHICSSFEQYNQYDKRETSQASKQDLQFN------NRKLLQDQ
EIRAELNKHFG------HLSQAVFEEETTKISELRDNSNFSDEQFSKLPMFINS--------------------------
-------GLTMDGLF-----------------------------------------------------------------
--------------------------------------------------------------------------------
------------------DDSEDENDKLC------------------------------CSWDGTQAYSLFDL---SPSC
S----------------------------------------------------------------SFNSPCGDSVSPPKS
LLSQRF-------------------------------------------QRIRSR---SRSFP--------QHRSCSHSP
YSRSRSRSPCSRFSSRSCYYYESSHCR-------------------------------PQAYRSSPLYSRSRSRSPYSHR
P---------------------RYDSYEEYQHERLKREEYRKEYE----------------------------KRESERA
KQRERQKQKAIEEQRVIYVGKIGPDTTRAELRDRFEVFGEIEECSVNLQDN-----------------------------
-------GDNYGFI-------------------------------------------------TYRYTCDAFAALENGYT
LRRTNEPDFELYFCGQKQFCKSNYADLDSNSDDFDP------------------------------------------AS
TKSKYDSMDFDSLLKEAQRSLRR---------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------
>Xenopus_tropicalis_PPARGC1A
--------------------------------------------------------------------------------
-------------------------------------------------MAWDMCNQDS--VWSDIECAALVG-------
-EDQPLCPDLPELDLS--ELDVNDLDADSFLGGLKWYSD-----------QSENISNQYSS--ESSNIFEKIDEENEENL
LAVLTETLDSLPVD------------------------------EDGLPSFDALTDGDVTNEHDPSLSSMPDGTPP----
--------------------------------------------------------------------------------
---TQEAEEPSLLKKLLLAPANAQLIYNECIGFTTQNHAS----------------------------------------
---------------PSQRIRTNSAVVKTENSWSNKPKT-----------------------------------------
-------------------ICHSQKPPRRPCSELLKYLTS----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------NDDPP-QTKSTESRNSRLD-------------------------------------------------------
---------KCSSKKKPYLQPQP---------HYQARATSLSLPLTPESPNDPKECPFIR--------------------
--------------------------------------------------------------------------------
-------------------KFSQDLLFVEFFFVIGLTPPTTPPHKANQENPFRTSPKLKS-CKSSVP-PAKKSRYIES--
------SSIQVLYPAK----------------------KGPEQSELYAQLSKAT--------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------VVIG-QEEKKA----KRPSLR-------
--------------------------------------------------------------------------------
--------------------------------LFGDHDYCQFMNS-----------------------------------
--------KSEIHISLSQELQASRHLECKDPLPG-KELKVCSYTDQ-EQCQ-KDSLPVTMPSSQNS------HRKQLQDQ
EIRAELNKHFG------HPTQAVYNDET-KISELVD-NKYSDEQLSRLPMFLTA--------------------------
-------GLEIDSLF-----------------------------------------------------------------
--------------------------------------------------------------------------------
------------------DDSEDENDKLC------------------------------YTWDETQSYSLFDE---SPSC
S----------------------------------------------------------------TFNSPSRYSVSPPTS
LFSQR--------------------------------------------ICSRSR---SRSFS--------QFRSSSLSP
YSRSRSRSPSSRSSSGSCCCYETDHCR-------------------------------EKT---SPMYARSRSRSPYGRR
P---------------------RYDSYEEYQHERLKREEYRKEYE----------------------------KRESERA
KQRERQRQKAIEEHRVIFVGKMRPNMSRAELRARFEVFGEIEECTVNLRDD-----------------------------
-------GNCYGFI-------------------------------------------------TYRYTCDAFAALENGYT
LRRSNEPDFEVCFCERKQVCKSNYADLDSNSDDFDP------------------------------------------AS
TKSKYDSMDFDSLLKEAQRSLRR---------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------
>Danio_rerio_PPARGC1A_a
--------------------------------------------------------------------------------
-------------------------------------------------MAWDRCNQDS--VWRELECAALVG-------
-EDQPLCPDLPELDLS--ELDVSDLDADSFLGGLKWYSD-----------QSEIISSQYGN--EASNLFEKIDEENEANL
LAVLTETLDSIPVD------------------------------EDGLPSFEALADGDVTNASDQSCPSTPDGSPR----
--------------------------------------------------------------------------------
---TPEPEEPSLLKKLLLAPANSQLSYNQYPGGKAQNHAAS---------------------------------------
----------------NQRIRPAPAVAKTENPWNSKPRGA----------------------------------------
-------------------CP--NRSMRRPCTELLKYLTS----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------SDE-AFQTKAGEAKSTWTGCGKDRGGACISSCSS-----------------------------SSSPSSSSTSS
FSSLSSCSSSTASKKKTSSASPSSQQQQLAVQAQRAKPTILPLPLTPESPNDHKGSPFEN--------------------
--------------------------------------------------------------------------------
-------------------KTIERTLSVEICGTPGLTPPTTPPHKASQENPFKVSLKNKLSSCSPSALTSKRPRLSNGGS
---CPQP---TSGSIR----------------------KGPEQTELYAQLSKASSTMPQG--------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------GLEDRRGKRPMPRVFGDHDYCQSTSTK-------
--------------------------------------------------------------------------------
--------------------------------RDSTTPAAVVPGPTEGRHVECKDLNM----------------------
--------PTSTTTTSSLSSTPPSSSSLARQLQGLSPTPQEACPDTYAHVQHHDSSSKMTMDCSSG------GRKLLRDQ
EIRDELNKHFG------KPQQAFYSGVVGEPRGKQP-IEDSDSGDEYPGLLGDY--------------------------
-------IHPGLPDF-----------------------------------------------------------------
--------------------------------------------------------------------------------
------------------EDLEVGRERLF------------------------------YLGEGSPLELLLEG---SPSS
SP---------------------------------------------------------------SSSSFSWCSVSPPSS
QLSP----------------------------QH------L----RWPRSISRSR---SRSSS--------HHRRRSLSR
SPYSRSGSPSSRSPSWSPRNMDESTFT-------------------------------PRICG----NPQSQSHSLFGRR
P---------------------RYDSYEEYQHERLKREEYRRDYE----------------------------KRECERA
EQRERQRQKAIEERRVVYVGRLRADSTRTELKRRFEVFGEIEESTVNLRHD-----------------------------
-------GDNFGFI-------------------------------------------------TYRYTCDALAALENGHT
LRRSNEPHFELCLGGQKQYSKSNYTDLDSHSDDFDP------------------------------------------AS
TKSKYDSMDFDSLLREAQYSLRR---------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------
>Takifugu_rubripes_PPARGC1A_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------KKIDEENEANL
LAVLTETLDSIPVD------------------------------EDGLPSFEALADGDVTNASDRSCPSSPDGSPR----
--------------------------------------------------------------------------------
---TPEPEEPSLLKKLLLAPANSQLSYNQYTGGQAQNHAAS---------------------------------------
---------------SNHRIRPPPAVVKMESTWNGKARGG----------------------------------------
-------------------SSQQNRPVRRHCTELLKYLTA----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------TDDILLHAKNNSSTSSSSS-------------------------------------------------------
---------SSASKKKSAASSQQQ--------QQPPKPTTLPLPLTPESPNDHKGSPFEN--------------------
--------------------------------------------------------------------------------
-------------------KTIERTLSVEIAGTPGLTPPTTPPHKASQENPFKASLKTKLSSCSSSASVCKRARLSESGP
GALAPAPGASGGGPIR----------------------KGPEQTELYAQLSKASTALP----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------YCITLRAAGGGPEERRSTGNNRRAAPR-------
--------------------------------------------------------------------------------
--------------------------------GYSDHDYCQASAK-----------------------------------
--------KDSSADTVTMTTAEQQDLSSVDGKAAPARGFGSARTPSGDDEDQLQTCAIS--------------RKLLRDN
QIRAELNKHFG------HPLQALYSQASQGREPPSH-----ANQAAAAPSLEGG--------------------------
-------FLPFHEEL-----------------------------------------------------------------
--------------------------------------------------------------------------------
------------------ELTQGRVSRFL------------------------------YPWEGTPLDLLFDCPPCSPSC
SPP--------------------------------------------------------------SSCSPSRGSVSPPSS
LLLSPS-------------------------------------------RPLCWTSAGSRSRS--------RSRSGSRSS
SSHYRRRSLSSSPDRRPSSWSRHNQDS-------------------------------STFRSRTQKSPRPQPRSPLSRR
P---------------------RYDSYEEYQHERLKREEYRRDYE----------------------------KRESERA
EQREKQRQKAIEERRVVYVGRLRSDCTRTELKRRFEVFGEIEECAVNLRDD-----------------------------
-------GDNFGFI-------------------------------------------------TYRYTCDAFAALENGHT
LRRSNEPQFELCFGGQKQFCKSHYTDLDSHSDDFDP------------------------------------------AS
TKSKYDSLDFDSLLREAQRSLRR---------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------
>Oryzias_latipes_PPARGC1A_a
--------------------------------------------------------------------------------
-------------------------------------------------MAWDRCNQDS--VWTELECAALVG-------
-EDQPLCPDLPELDLS--ELDVSDLDADSFLGGLKWYSD-----------QSEIVSTQYGN--EASNLFEKIDEENEANL
LAVLTETLDSIPVD------------------------------EDGLPSFEALADGDVTNASDRSCPSSPDGSPR----
--------------------------------------------------------------------------------
---TPEPEEPSLLKKLLLAPANSQLSYNQYTGGKAQNHAAS---------------------------------------
---------------SNHRIRPPPAVVKTESPWNGKARGG----------------------------------------
-------------------SSQQNRPVRRPCTELLKYLTA----------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------TDDILLHTKGSEPKSAWGG-------------------------------------------------------
----------ASSKDKSGLALPSQQP--LQQHHQRAKPTTLPLPLTPESPNDYKGSPFEN--------------------
--------------------------------------------------------------------------------
-------------------KTIERTLSVEIAGTPGLTPPTTPPHKASQENPFKASLKTKLSSCSSSALTCKRSRLSELGA
CVVALAPGASAGGPAR----------------------KGPEQTELYAQLSKASTALP----------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------YTIAPYAVGGGLEEHRSPGNNKRACPR-------
--------------------------------------------------------------------------------
--------------------------------GHSDHDYCQASARSK--------AAG----------------------
--------GTATVTTVEMTFTPRASDASMPSSGKQTLTQASPIPAFGAASMRDQP------QLCAT------SRKPLCDQ
EIRAELNKHFG------HHPQAVHSQAP-QPAVAGE-NDYYSQKLLGSSYLHTG--------------------------
-------FLPFHDEI-----------------------------------------------------------------
--------------------------------------------------------------------------------
------------------ELGEGRDSRFV------------------------------YPWEGTPLDLLFDC---SPSS
PS---------------------------------------------------------------CSPPS---SCSPSRG
SLSPPSSLLLSP-------------------NRP------F----CWTTSGSRSR---SRSHS--------GSRSSSSRY
RRRSLSSSPDRRPPSWSRHSTDLNVSR-------------------------------SRTHK----SPRPQSRSPLSRR
P---------------------RYDSYEEYQHERLKREEYRLDYE----------------------------KREFERA
EQREKQRQKAIEERRVVYVGRLRSDCTRTELKRRFEVFGEIEECAVNLRDD-----------------------------
-------GDNFGFI-------------------------------------------------TYRYTCDAFAALENGHT
LRRPNDPQFELCFGGQKQFCKSHYTDL-----------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------
>Homo_sapiens_PPARGC1B
--------------------------------------------------------------------------------
----------------------------------------------MAGNDCGALLDEELSSFFLNYLADTQG-----GG
SGEEQLYADFPELDLS--QLDASDFDSATCFGELQWCPE-----------NSETEPNQYSP--DDSELFQID-SENEA-L
LAELTKTLDDIPED------------------------------DVGLAAFPALDGGDALSCTSASPAPSSAPPSP----
--------------------------------------------------------------------------APE-KP
SAPAPEVDELSLLQKLLLATSYPTSSSDTQKEGTAWRQAG----------------------------------------
----------------LRSKSQRPCVKAD--STQDKKAP-----------------------------------------
----------------------MMQSQSRSCTELHKHLTS----AQCCLQ------DRGLQ----PPCLQSPRLPAK---
--------------------------------------------------------------------------------
-------------------------------------------------------------------------------E
DKE-PGEDCPSPQPAPASPRDSLALGRADPG----------------------------------------------APV
SQEDMQAMVQLIRYMHTYCLPQRKLP---PQTPEPLP-KACSNPSQQVRSRPWSRHHSKA--------------------
--------------------------------------------------------------------------------
--------------SWAEFSILRELLAQDVLCDVSKPYRLATPVYASLTPRSRPRPPKDSQASPGRPSSVEEVRIAASPK
STGPRPSLRPLRLEVKREVRRPARLQQ-----QEEEDEEEEEEEEEEEKEEEEE--WGRK--------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------RPGRGLPWTKLGRKLESSVCPVRRSRR-------
--------------------------------------------------------------------------------
--------------------------------LNPELGPWLTFADEP--LVPSEPQG-----ALPSLCLAPKAYD-----
-VERELGSPTDEDSGQDQQLLRGPQIPALESPC-ESGCGDMDEDPSCPQLPPRDSPRCLMLALSQS---DPTFGKKSFEQ
TLTVELCGTAG----LTPPTTPPYKPTEEDPFKPDIKHSLGKEIALSLPSPEGL--------------------------
--SLKATPGAAHKLP-----------------------------------------------------------------
--------------------------------------------------------------------------------
------------------KKHPERSELLS--HLRHATA----------------QPASQAGQKRPFSCSFGDHDYCQVLR
PEG--------------------------------------------------------------VLQRKVLRSWEPSGV
HLEDWPQQGAPW-AEAQAPGREEDRSCDAGAPPK------D----STLLRDHEIRASLTKHFGLLETALEEEDLASCKSP
EYDTVFEDSSSSSGESSFLPEEEEEEGEEEEEDDEEEDSGV-----------------SPTCSDHCPYQSPPSKANRQLC
S---------------------RSRSSSGSSPCHSWSPATRRNFR---CESRGPCSD----------------RTPS-IR
HARKRREKAIG-EGRVVYIQNLSSDMSSRELKRRFEVFGEIEECEVLTRNR-----------------------------
------RGEKYGFI-------------------------------------------------TYRCSEHAALSLTKGAA
LRKRNEPSFQLSYGGLRHFCWPRYTDYDSNSEEALP------------------------------------------AS
GKSKYEAMDFDSLLKEAQQSLH----------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------
>Pan_troglodytes_PPARGC1B
--------------------------------------------------------------------------------
----------------------------------------------MAGNDCGALLDEELSSFFLNYLADTQG-----GG
SGEEQLYADFPELDLS--QLDASDFDSATCFGELQWCPE-----------NSETEPNQYSP--DDSELFQID-SENEA-L
LAELTKTLDDIPED------------------------------DVGLAAFPALDGGDALSCTSASPAPSSAPPSP----
--------------------------------------------------------------------------APE-KP
SAPAPEVDELSLLQKLLLATSYPTSSSDTQKEGTAWRQAG----------------------------------------
----------------LRSKSQRPCVKAD--STQDKKPP-----------------------------------------
----------------------VTQSQSRSCTELHKHLTS----AQCCLQ------DRGLQ----PPCLQSPRLPAK---
--------------------------------------------------------------------------------
-------------------------------------------------------------------------------E
DKE-PGEDCPSPQPAPASPRDSLALGRADPG----------------------------------------------APV
SQEDMQAMVQLIRYMHTYCLPQRKLP---PQTPEPLP-KACSNPSQQVRSRPWSRHHSKA--------------------
--------------------------------------------------------------------------------
--------------SWAEFSILRELLAQDVLCDVSKPYRLATPVYASLTPRSRPRPPKDSQASPGRPSSVEEVRIAASPK
STGPRPSLRPLRLEVKREVRRPARLQQ-----QEEEDEEEEEEEEEEEKEEEEE--WGRK--------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------RPGRGLPWTKLGRKLESSVCPVRRSRR-------
--------------------------------------------------------------------------------
--------------------------------LNPELGPWLTFADEP--LVPSEPQG-----ALPSLCLAPKAYD-----
-VERELGSPTDEDSGQDQQLLRGPQIPALESPC-ESGCGDMDEDPSCPQLPPRDSARCLMLALSQS---DPTFGKKSFEQ
TLTVELCGTAG----LTPPTTPPYKPTEEDPFKPDIKHSLGKEIALSLPSPEGL--------------------------
--SLKATPGAAHKLP-----------------------------------------------------------------
--------------------------------------------------------------------------------
------------------KKHPERSELLS--HLRHATA----------------QPASQAGQKRPFSCSFGDHDYCQVLR
PEG--------------------------------------------------------------VLQRKVLRSWEPSGV
HLEDWPQQDAPR-AEAQAPGREEDRSCDAGAPPK------D----STLLRDHEIRASLTKHFGLLETALEEEDLASCKSP
EYDTVFEDSSSSSGESSFLPEEEEEEGEEEEEDNEEEDSGV-----------------SPTCSDHCPYQSPPSKANRQLC
S---------------------RSRSSSGSSPCHSWSPATRRNFR---CESRGPCSD----------------RTPS-IR
HARKRREKAIG-EGRVVYIQNLSSDMSSRELKRRFEVFGEIEECEVLTRNR-----------------------------
------RGEKYGFI-------------------------------------------------TYRCSEHAALSLTKGAA
LRKRNEPSFQLSYGGLRHFCWPRYTDYDSNSEEALP------------------------------------------AS
GKSKYEAMDFDSLLKEAQQSLH----------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------
>Pongo_abelii_PPARGC1B
--------------------------------------------------------------------------------
----------------------------------------------MAGNDCGALLDEELSSFFLNYLADTQG-----GG
SGEEQLYADFPELDLS--QLDASDFDSATCFGELQWCPE-----------NSETEPNQYSP--DDSELFQID-SENEA-L
LAELTKTLDDIPED------------------------------DVGLAAFPALDGGDALSCTSASPAPSSAPPSP----
--------------------------------------------------------------------------APE-KP
SASAPEVDELSLLQKLLLATSYPTSSSDTQKEGTAWRQAG----------------------------------------
----------------LRSKSQRPCVKAD--STQDKKAP-----------------------------------------
----------------------MTQSQSRSCTELHKHLTS----AQCCLQ------DRGLQ----PPCLQSPRLPAK---
--------------------------------------------------------------------------------
-------------------------------------------------------------------------------E
DKE-PGEDCPSPQPAPASPRDSLALGRADPG----------------------------------------------TPV
SQEDMQAMVQLIRYMHTYCLPQRKLP---PQAPEPLP-KACSNPSQQVRSRPWSRHHSKA--------------------
--------------------------------------------------------------------------------
--------------SWAEFSILRELLAQDVLCDVSKPYRLATPVYASLTPRSRPRPPKDSQASPGRPSSVEEVRIAASPK
STGPRPSLRPLRLEVKGEVRRPARLQQ-----QEEEDEEEEEEEEEEEKEEEEE--WGRK--------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------RPGRGLPWTKLGRKLESSVCPVRRSRR-------
--------------------------------------------------------------------------------
--------------------------------LNPELGPWLTFADEP--LVPSEPQG-----ALPSLCLAPKAYD-----
-VERELGSPTDEDSGQDQQLLRGPQIPALESPC-ESGCGDMDEDPSCPQLPPRDSPRCLMLALSQS---DPTFGKKSFEQ
TLTVELCGTAG----LTPPTTPPYKPTEEDPFKPDIKHSLGKEIALSLPSPEGL--------------------------
--SLKATPGAAHKLP-----------------------------------------------------------------
--------------------------------------------------------------------------------
------------------KKHPERSELLS--HLRHATA----------------QPASQAGQKRPFSCSFGDHDYCQVLR
PEG--------------------------------------------------------------ILQRKVLRSWEPSGV
HLEDWPQQGAPR-AEAQAPGREEDRSRDAGTPPK------D----SMLLRDHEIRASLTKHFGLLETALEEEDLASCKSP
EYDTVFEDSSSSSGESSFLPEEEEEEGEEEEEDNEEEDSGV-----------------SPTCSDHCPYQSPPSKANRQLC
S---------------------RSRSSSGSSPCHSWSPATRRNFR---CESRGPCSD----------------RTPS-IR
HARKRREKAIG-EGRVVYIQNLSSDMSSRELKRRFEVFGEIEECEVLTRSR-----------------------------
-------GEKYGFI-------------------------------------------------TYRCSEHAALSLTKGAA
LRKRNEPSFQLSYGGLRHFCWPRYTDYDSNSEEALP------------------------------------------AS
GKSKYEAMDFDSLLKEAQQSLH----------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------
>Mus_musculus_PPARGC1B
--------------------------------------------------------------------------------
----------------------------------------------MAGNDCGALLDEELSSFFLNYLSDTQG-----GD
SGEEQLCADLPELDLS--QLDASDFDSATCFGELQWCPE-----------TSETEPSQYSP--DDSELFQID-SENEA-L
LAALTKTLDDIPED------------------------------DVGLAAFPELDEGDTPSCTPASPAPLSAPPSP----
--------------------------------------------------------------------------TLE-RL
LSPASDVDELSLLQKLLLATSSPTASSDALKDGATWSQTS----------------------------------------
----------------LSSRSQRPCVKVD--GTQDKKTP-----------------------------------------
----------------------TLRAQSRPCTELHKHLTS----VLPCPR------VKACS----PTPHPSPRLLSK---
--------------------------------------------------------------------------------
-------------------------------------------------------------------------------E
EEEEVGEDCPSPWPTPASPQDSLAQDTASPDS---------------------------------------------AQP
PEEDVRAMVQLIRYMHTYCLPQRKLP---QRAPEPIP-QACSSLSRQV--QPRSRHPPKA--------------------
--------------------------------------------------------------------------------
--------------FWTEFSILRELLAQDILCDVSKPYRLAIPVYASLTPQSRPRPPKDSQASPAHSAMAEEVRITASPK
STGPRPSLRPLRLEVKRDVNKPTRQKR------EEDEEEEEEEEEEEEEKEEEEEEWGRK--------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------RPGRGLPWTKLGRKMDSSVCPVRRSRR-------
--------------------------------------------------------------------------------
--------------------------------LNPELGPWLTFTDEP--------LG-----ALPSMCLDTETHN-----
-LEEDLGSLTD--SSQGRQLPQGSQIPALESPC-ESGCGDTDEDPSCPQPTSRDSSRCLMLALSQS----DSLGKKSFEE
SLTVELCGTAG----LTPPTTPPYKPMEEDPFKPDTKLSPGQDTAPSLPSPEAL--------------------------
--PLTATPGASHKLP-----------------------------------------------------------------
--------------------------------------------------------------------------------
------------------KRHPERSELLS--HLQHATT----------------QPVSQAGQKRPFSCSFGDHDYCQVLR
PEA--------------------------------------------------------------ALQRKVLRSWEPIGV
HLEDLAQQGAPLPTETKAPRREANQNCDP--THK------D----SMQLRDHEIRASLTKHFGLLETALEGEDLASCKSP
EYDTVFEDSSSSSGESSFLLEEEEEEEEGGEEDDEGEDSGV-----------------SPPCSDHCPYQSPPSKASRQLC
S---------------------RSRSSSGSSSCSSWSPATRKNFR---RESRGPCSD----------------GTPS-VR
HARKRREKAIG-EGRVVYIRNLSSDMSSRELKKRFEVFGEIVECQVLTRSK-----------------------------
------RGQKHGFI-------------------------------------------------TFRCSEHAALSVRNGAT
LRKRNEPSFHLSYGGLRHFRWPRYTDYDPTSEESLP------------------------------------------SS
GKSKYEAMDFDSLLKEAQQSLH----------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------
>Rattus_norvegicus_PPARGC1B
--------------------------------------------------------------------------------
----------------------------------------------MAGNDCGALLDEELSSFFLNYLSDTQG-----GE
SGEEQLCADLPELDLS--QLDASDFDSATCFGELQWCPE-----------TSETEPSQYSP--DDSEFFQID-SENEA-L
LAALTKTLDDIPED------------------------------DVGLAAFPGLDEGDTPSCTPASPAPLSVPPSP----
--------------------------------------------------------------------------ALE-RL
LSPVSEVDELSLLQKLLLATSSPTASSDALKDGATWSQTS----------------------------------------
----------------LSSRSQRPCVKVD--GTQDKKTP-----------------------------------------
----------------------MLRSQSRPCTELHKHLTS----VLPCPR------GKACS----PPPHPSPQLLSK---
--------------------------------------------------------------------------------
-------------------------------------------------------------------------------E
DEE-VGEDCPSPWPAPASPQDSLGQDTANPNS---------------------------------------------AQV
PKDDVRAMVQLIRYMHTYCLPQRKLP---QRASEPIP-QSCSSPLRKV--PPRSRQTPKA--------------------
--------------------------------------------------------------------------------
--------------FWTEFSILRELLAQDILCDVSKPYRLATPVYASLTPQSRTRPPKDSQASPAHSAMAEEVRITASPK
STGPRPSLRPLRLEVKRDVNKPARQKR------EEDEEEEEEEEEEEE-KEDEEEEWGRK--------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------RPGRGLPWTKLGRKMDSSVCPVRRSRR-------
--------------------------------------------------------------------------------
--------------------------------LNPELGPWLTFTDEP--------LG-----ALPSMCLATETHD-----
-LEEELGGLTD--SSQGQQLPLGSQIPTLESPC-ESGCGDTDEDPSCPRPPSRDSPRCLMLALSQS----DPLGKKSFEE
SLTVELCGTAG----LTPPTTPPYKPMEEDPFKQDTKHSPGQDTAPSLPSPETL--------------------------
--QLTATPGASHKLP-----------------------------------------------------------------
--------------------------------------------------------------------------------
------------------KRHPERSELLS--HLQHATT----------------QPVSQAGQKRPFSCSFGDHDYCQVIR
PEA--------------------------------------------------------------ALQRKVLRSWEPIKV
HLEDLAHQGATLPVETKTPRREADQNCDP--TPK------D----SMQLRDHEIRASLTKHFGLLETALEEEDLASCKSP
EYDTVFEDSSSSSGESSFLLEEEEEE--GGEEDDEGEDSGV-----------------SPPCSDHCPYQSPPSKASRQLC
S---------------------RSRSSSGSSSCSSWSPATRKNFR---LESRGPCSD----------------GTPS-AR
HAKKRREKAIG-EGRVVYIRNLSGDMSSRELKKRFEVFGEIVECQVLRRSK-----------------------------
------RGQKHGFI-------------------------------------------------TFRCSEHAALSVRNGAT
LRKRNEPSFHLSYGGLRHFRWPRYTDYDPTSEESLP------------------------------------------SS
GKSKYEAMDFDSLLKEAQQSLH----------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------
>Canis_familiaris_PPARGC1B
--------------------------------------------------------------------------------
----------------------------------------------MAGNDCGALLDEELSSFFLNYLADAQS-----GV
SGEEQLCADFPELDLS--QLDASDFDSATCFGELQWCPE-----------NSETEPSQYSP--DDSELFQITDSENEA-L
LAALTKTLDDIPED------------------------------DVGLAAFPALDGGDAPSCTSASPAPSSSPPSPSP--
--------------------------------------------------------------------------SLE-RP
QPPAPEVDDLSLLQKLLLATSYPASSSDTQKEGTTWRQAG----------------------------------------
----------------LRSRNQRPCVKMD--STQDKKAP-----------------------------------------
----------------------TVQSQGRSCTELHKHLTS----VPSCPQTKARSPDRGLQ----PPPALSPPLPAK---
--------------------------------------------------------------------------------
-------------------------------------------------------------------------------E
DEE-ASEDCPSPQPAPALPQDSPTPGRAGPG----------------------------------------------TQV
SREDMQAMVQLIRYMHTYCLPQRKLP---PQASEPAP-QPCSSPSKQVKPRPRSQHPSKG--------------------
--------------------------------------------------------------------------------
--------------SWAEFSILRELLAQDVLCDVSKPYRLATPVYASLTPRPRPRPPKDSQASPGHPSPVEEVRITASPR
STGPRPSLRPLRLDVKGHTGRTARLQR----EEEEEEEDEEEE-EDEKDEEEEEEEWGRK--------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------RPGRGLPWTKLGRKLESSVCPVRRSRR-------
--------------------------------------------------------------------------------
--------------------------------LNPELGPWLAFSDES--LVPVEPQG-----TLPSLRLAPEAYD-----
-VEGALGSPTDEDSGQDQQLPRGPQIPALESPC-ESGCGDTDEDPSCPRLPSRDSPRCLMLALSQS---DTPFGRKSFEQ
TLTVELCGTA----GLTPPTTPPYKPTEEDPFKPDIKHSPGKDRALSLPSLEGL--------------------------
--QLGPTTAAAPKLP-----------------------------------------------------------------
--------------------------------------------------------------------------------
------------------KKHPERSELLS--HLRHATA----------------QPASQTGQKRPFSCSFGDHDYCQVLK
PEG--------------------------------------------------------------ALQRKVLRSWEPSGV
HLEDCHQQGAPR-AEVQASAREEDRSCDSGGPAK------D----SVPLRDHEIRASLTKHFGLLETALEDEDLASCKSP
EYDTVFEDSSSSSGESSFLLEEEEEEE------DEEEDSGV-----------------SPPRSDHCPYQSPPSKASRQLC
S---------------------RSRSSSGSSSCRSRSPATRRTFR---CESRGPCSD----------------RTPS-VR
HARKRREKAIG-EGRVVYVRNLSSDMSSRELKRRFEVFGEIVECQVLTRSK-----------------------------
------RGEKYGFI-------------------------------------------------TYRCSEHAALSLRNGAA
LRKRHEPSFQLSYGGLQHFCWPRHTDYDSNSEEALP------------------------------------------AS
VKTKYEAMDFDSLLKEAQQSLH----------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------
>Felis_catus_PPARGC1B
--------------------------------------------------------------------------------
----------------------------------------------MR----RVICWTRIHVMFAGNTLLRKG-----GG
SGEEQLCADFPELDLS--QLDASDFDSATCFGELQWCPE-----------SSETEPSQYSP--DDSELFQIIDSENEA-L
LAALTKTLDDIPED------------------------------DVGLAAFPALDGGDAPSCTSASPAPSSAPPSPSP--
--------------------------------------------------------------------------SLE-RP
QAPAPEVDELSLLQKLLLATSHPSSSSDTQKEGATWRQAG----------------------------------------
----------------LRSKSQRPCVKMD--GTQDKKVP-----------------------------------------
----------------------TVQSQSRSCTELHRHLTS----VPSCPQTKARSPDRGLQ----PPPALSPQLPAK---
--------------------------------------------------------------------------------
-------------------------------------------------------------------------------E
EEE-PGEDCPSPQPAPALPQDSPAPGRARPG----------------------------------------------TQV
SREDMHAVVQLIRYMHTYCLPQRKLP---PQAPEPAP-QPCSSPSKQVKPQPRSQHPSKA--------------------
--------------------------------------------------------------------------------
--------------SWAEFSILRELLAQDVLCDVSKPYRLATPVYASLTPRPRPRPPRDSQASPGHPSPVEEVRITASPR
STGPRPSLRPLRLEVKGRAGRSARLQQQ-QEEEDEEEDEDEEE-EEEKEEEEEEEEWGRK--------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------RPGRGLPWTKLGRKPESSVCPVRRSRR-------
--------------------------------------------------------------------------------
--------------------------------LNPELGPWLTFSDES--LVPAEPQG-----ALSSLHLAPEAYD-----
-MEGALGSPTDEDSGQDQQLPRGPQIPALESPC-ESGCGDTDEDPSCPRLPSRDSPRCLMLALSQS---DPPFGKKSFEQ
TLTVELCGTA----GLTPPTTPPYKPTEEDPFKPDIKHSPGKDRAPSLPSLEGL--------------------------
--QLEAAAGAAHKLP-----------------------------------------------------------------
--------------------------------------------------------------------------------
------------------KKHPERSELLS--HLRHATA----------------QPASQTGQKRPFSCSFGDHDYCQVLK
PEG--------------------------------------------------------------ALQRKVLRSWEPSGV
HLEDWPQQGALQ-AEVQASNREEDRSRDASAPAK------D----SVLLRDHEIRASLTKHFGLLESALEDEDLASCKSP
EYDTVFEDSSSSSGESSFLLEEEEEEEE----DDEEEDSGV-----------------SPPCSDHCPYQSPPSKAGRQLC
S---------------------RSRSSSCSSSCRSRSPAIRRTFR---CESRGPCSD----------------GTPS-VR
HARKRREKAIG-EGRVVYVRNLSSDMSSRELKRRFEVFGEIVECQVLTRNN-----------------------------
------RGEKYGFI-------------------------------------------------TYRCSEHAALSLRNGAA
LRKRNEPSFQLSYGGLQHFCWPRHTDYDSNSEETLP------------------------------------------AS
VKNKYEAMDFDSLLKEAQQSLH----------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------
>Bos_taurus_PPARGC1B
--------------------------------------------------------------------------------
-------------------------------------------------AKGSDCQYPKLSSDPPPFYLSPQG-----GG
SGEEQLCADFPELDLS--QLDANDFDSATCFEELQWCPE-----------NSETDPSEYSP--DDLELFQIIDSENEA-L
LAALTKTLDDMPED------------------------------VVSLAAFPALDDGDTPSCASASPIPSSAPPSP----
--------------------------------------------------------------------------SLE-GP
PASAPEVDELSLLQKLLLATSYPTSASDSQKEGTAWRQAG----------------------------------------
----------------LRSRNQRPCVKMD--GPQDRKAP-----------------------------------------
----------------------TPHPQSRSCTELHKHLTS----APSCPRAKALSPDRALQ----PPPSLSPRLPTK---
--------------------------------------------------------------------------------
-------------------------------------------------------------------------------E
DEE-AGEDCPSPQLAPASPGDSPALGRTDPS----------------------------------------------AQV
SQEDMQAMVQLIRYMHTYCLPQRKLP---TQAPEPAP-QPSSSPAKQVRPRPRSQHPSKA--------------------
--------------------------------------------------------------------------------
--------------AWTEFSILRELLAQDVLCDVSKPYRLATPVYASLTPRPR---PKDSQASAGHPGLVEEVRVSPSSK
SSGPRPSLRPLRLQVKGHVSRSARLQP-------EEEEEEEEEEEEEEKEEEDEEEWGRK--------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------RPGRGLPWTKLGRKPESSVCPVRRSRR-------
--------------------------------------------------------------------------------
--------------------------------LNPELGPWLTFTDEP--MVPAEPQG-----PLPSR-LAPEAYD-----
-VEGEPGSPTDEDSGQDQLLLRGPQIPALESPC-ESGCGDTDEDPSCLRLSSRDSPRCLMLALSQSPTGDPPFGKKSFEQ
TLAVELCGTAAWV-GLTPPTTPPYKPTEEDPFKPDIKHSPGKDRAP---TPEGP--------------------------
--QLGATAEAAHKLP-----------------------------------------------------------------
--------------------------------------------------------------------------------
----------------