>Homo_sapiens_PITX1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MDAFKGG----------------------------MSLERLP-------------E
GLRPPPPPPHDMGPAFHLARP-ADP-REPLENSA--------------SESSDTELPE----------------------
-KERGGEPKGPEDSGAGG---------------------------------------------------TGCG-GADDPA
KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQ-----LDLCKGG
YVPQFSGLVQPYED-VYAAG-YSYNNWAAKSLAPAPLSTKSFTF-FN---SM--SPLSSQSMFSA-PSSISS-MTMPSSM
GPGAVPGMPN-SGLNNINN---LTGSS--LNSAMSP------GACPYGT--PASPYSVYR-----DTCNSSLASLRLKSK
QHSSF----GYGG---LQGP--AS---GLNACQYN---S-----
>Mus_musculus_PITX1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MDAFKGG----------------------------MSLERLP-------------E
GLRPPPPPPHDMGPSFHLARA-ADP-REPLENSA--------------SESSDADLPD----------------------
-KERGGEAKGPEDGGAGS---------------------------------------------------AGCGGGAEDPA
KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQ-----LDLCKGG
YVPQFSGLVQPYED-VYAAG-YSYNNWAAKSLAPAPLSTKSFTF-FN---SM--SPLSSQSMFSA-PSSISS-MTMPSSM
GPGAVPGMPN-SGLNNINN---LTGSS--LNSAMSP------GACPYGT--PASPYSVYR-----DTCNSSLASLRLKSK
QHSSF----GYGG---LQGP--AS---GLNACQYN---S-----
>Pan_troglodytes_PITX1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MDAFKGG----------------------------MSLERLP-------------E
GLRPPPPPPHDMGPAFHLARP-ADP-REPLENSA--------------SESSDTELPE----------------------
-KERGGEPKGPEDSGAGG---------------------------------------------------TGCG-GADDPA
KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQ-----LDLCKGG
YVPQFSGLVQPYED-VYAAG-YSYNNWAAKSLAPAPLSTKSFTF-FN---SM--SPLSSQSMFSA-PSSISS-MTMPSSM
GPGAVPGMPN-SGLNNINN---LTGSS--LNSAMSP------GACPYGT--PASPYSVYR-----DTCNSSLASLRLKSK
QHSSF----GYGG---LQGP--AS---GLNACQYN---S-----
>Macaca_mulatta_PITX1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MDAFKGG----------------------------MSLERLP-------------E
GLRPPPPPPHDMGPAFHLARP-ADH-REQLENSA--------------SESSDTELPE----------------------
-KERGGESKGPEDSGTGG---------------------------------------------------TGCG-SADDPA
KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQ-----LDLCKGG
YVPQFSGLVQPYED-VYAAG-YSYNNWAAKSLAPAPLSTKSFTF-FN---SM--SPLSSQSMFSA-PSSISS-MTMPSSM
GPGAVPGMPN-SGLNNINN---LTGSS--LNSAMSP------GACPYGT--PASPYTVYR-----DTCNSSLASLRLKSK
QHSSF----GYGG---LQGP--AS---GLNACQYN---S-----
>Rattus_norvegicus_PITX1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MDAFKGG----------------------------MSLERLP-------------E
GLRPPPPPPHDMGPSFHLART-ADP-REPLENSA--------------SESSDADLPD----------------------
-KERGGEAKVPEDGGAGS---------------------------------------------------AGCG-SAEDPA
KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQ-----LDLCKGG
YVPQFSGLVQPYED-VYAAAGYSYNNWAAKSLAPAPLSTKSFTF-FN---SM--SPLSSQSMFSA-PSSISS-MTMPSSM
GPGSVPGMPN-SGLNNINN---LTGSS--LNSAMSP------GACPYGT--PASPYSVYR-----DTCNSSLASLRLKSK
QHSSF----GYGG---LQGP--AS---GLNACQYN---S-----
>Canis_familiaris_PITX1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MDAFKGG----------------------------MSLERLP-------------E
GLR-PPPPPHDMGPAFHLARA-ADP-REPLENSA--------------SESSDTELPE----------------------
-KERGGEVKGPEDSGAGG---------------------------------------------------AGCG-GAEDPA
KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQ-----LDLCKGG
YVPQFSGLVQPYED-VYAAG-YSYNNWAAKSLAPAPLSTKSFTF-FN---SM--SPLSSQSMFSA-PSSISS-MTMPSSM
GPGAVPGMPN-SGLNNINN---LTGSS--LNSAMSP------GACPYGT--PASPYSVYR-----DTCNSSLASLRLKSK
QHSSF----GYGG---LQGP--AS---GLNACQYN---S-----
>Bos_taurus_PITX1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MDAFKGG----------------------------MSLERLP-------------E
GLRPPPPQPHDMGPAFHLART-ADP-REPLENSA--------------SESSDTELPE----------------------
-KERGGEPKGPEDSGAGG---------------------------------------------------AGCG-GAEDPA
KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQ-----LDLCKGG
YVPQFSGLVQPYDD-VYAAG-YSYNNWAAKSLAPAPLSTKSFTF-FN---SM--SPLSSQSMFSA-PSSISS-MTMPSSM
GPGAVPGMPN-SGLNNINN---LTGSS--LNSAMSP------GACPYGT--PASPYSVYR-----DTCNSSLASLRLKSK
QHSSF----GYGG---LQGP--AS---GLNACQYN---S-----
>Pteropus_vampyrus_PITX1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MDAFKGG----------------------------MSLERLP-------------E
GLRPPPPPPHDMGPAFHLARA-ADP-REPLENSA--------------SESSDTELPE----------------------
-KERSGESKGPEDSGAGG---------------------------------------------------AGCG-GAEDPA
KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQ-----LDLCKGG
YVPQFSGLVQPYED-VYAAG-YNYN-WATKSLAPAPLSTKSFTF-FN---SM--SPLSSQSMFSA-PSSISS-MTMPSSM
GPGAVPGMPN-SGLNNINN---LTGSS--LNSAMSP------GACPYGT--PASPYSVYR-----DTCNSSLASLRLKSK
QHSSF----GYGG---LQGP--AS---GLNACQYN---S-----
>Monodelphis_domestica_PITX1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MDSFKG----------------------------GMGLERLP-------------E
GLRPPPP--HDMSSSFHLARA-SDS-REPLENSA--------------SESSDTEVPE----------------------
-KERSGETKGNEDGGG------------------------------------------------------------EDPA
KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQ-----MDLCKNG
YVPQFSGLVQPYED-VYAG--YTYNNWAAKSLTPAPLSTKGFTF-FN---SM--SPLSSQSMFSA-PSTISS-MSMPSGM
GHSAVPGMPN-SSLNNINNLNNLTGSS--LNSAMSS------SACPYGP--PGSPYSVYR-----DTCNSSLASLRLKSK
QHSTF----GYSS---LQSP--GS---GLNACQYN---S-----
>Gallus_gallus_PITX1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MDSFKG----------------------------GMNLERLP-------------E
SLRPQPS--HDMASSFHLQRS-SEP-RDPIENSA--------------SESSDTEVPER------------KRGK-ENLT
KREGGGGNAA-ADGAA------------------------------------------------------------DDPA
KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQ-----MDLCKNG
YVPQFSGLMQPYDD-MYAG--YPYNNWATKSLTPAPLSTKSFTF-FN---SM--SPLSSQSMFSA-PSSISS-MNMPSGM
GHSAVPGMAN-SGLNNIN---NISGSS--LNSAMSS------PACPYGP--PGSPYSVYR-----DTCNSSLASLRLKSK
QHSSF----GYSS---LQSP--GS---SLNACQYN---S-----
>Taeniopygia_guttata_PITX1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MDSFKG----------------------------GMNLERLP-------------E
SLRPQPS--HDMASSFHLQRS-SEP-RDPIDNSA--------------SESSDTEVPEP------------ERQRGAKAG
KKERSGEQKN-EDGAA------------------------------------------------------------DDPA
KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQ-----MDLCKNG
YVPQFSGLMQPYDD-MYAG--YPYNNWATKSLTPAPLSTKSFTF-FN---SM--SPLSSQSMFSA-PSSIPS-MNMPSSM
GHSAVPGMAN-SGLNNIN---NISGSS--LNSAMSS------PACPYGP--PGSPYSVYR-----DTCNSSLASLRLKSK
QHSSF----GYSS---LQSP--GS---SLNACQYN---S-----
>Xenopus_tropicalis_PITX1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MDSFKG----------------------------AMNLERLP-------------E
SLRPQPS--HDMATSFHLQRS-SEA-RDPMDNSA--------------SESSDTEIAE----------------------
-KERSGEPKG-EDGNG------------------------------------------------------------DDPT
KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----MDLCKNG
YVPQFSGLMQPYDE-MYAG--YPYNNWATKSLTPAPLSTKSFTF-FN---SM--SPLSSQSMFSG-PSSISS-MSMPSSM
GHSAVPGMPN-SSLNNINNLNNISSSS--LNSAMSS------TACPYGP--PGSPYTVYR-----DTCNSSLASLRLKSK
QHSTF----GYSS---LQSP--AS---SLNACQYN---S-----
>Danio_rerio_PITX1a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------MNVD-----------------
-----------MASSFHLPRS-ASSTRETLENTS--------------SESSDTEAAE----------------------
-KERSVEQRS-DDGNA------------------------------------------------------------DDP-
KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----MDLCKNS
YLPQFSGLMQPYDD-VYPT--YTYNNWTNKGLTPAPLSTKNFTF-FN---SM--SPLTSQSMFSA-PSSISS-MSMASGM
GHSAVPGMPT-TGLNNIGNLNGIGGST--INPAMSS------STCPYGP--PGSPYSVYR-----DTCNSSLATLRLKSK
QHPSF----GYSG---LQSP--GS---SLNACQYN---S-----
>Takifugu_rubripes_PITX1a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------------HSDN
WFVFSCFAGNVMSCKPNSEEAGMELNLSKNGISCVDPG--------------------GMNLDRIA-------------E
AARAPPP--RDVAPAFHLPRT-SNSSRDTLENSS--------------SESSDTDLAE----------------------
-KERSAEQRS-DDGNA------------------------------------------------------------DDP-
KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----MDLCKNS
YLPQFSGLMQPYED-MYPA--YTYNNWTNKGLTPAPLSTKNFTF-FN---SM--SPLTSQSMFSA-PSSISS-MTMASGM
GPSAVPGMPT-PGLNNISNLNGIGTSG--INSAMSS------PACPYGP--PGSPYSVYR-----DTCNSSLATLRLKSK
QHPTF----GYSG---LQSP--GT---SLNACQYN---S-----
>Tetraodon_nigroviridis_PITX1a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------MELNLSKNGISCVDPGS-------------------GMNLDRIA-------------E
AARAPPP--RDGAPAFHLPRS-SNSRRETLENSS--------------SESSDTDLAE----------------------
-KERSAEQRS-DDGAA------------------------------------------------------------DDP-
KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----MDLCKNS
YLPQFSGLMQPYDD-MYPA--YTYNNWTNKGLAPAPLSTKNFTF-FN---SM--SPLTSQSMFSA-PNSISS-MTMASGM
GPSAVPGMPA-PGLNNISNLNGIGTSG--INSAMSS------PACPY-P--PGSPYSVYR-----DTCNSSLATLRLKSK
QHPTF----GYSG---LQSP--GS---GLNACQYN---S-----
>Oryzias_latipes_PITX1a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------MNLDRIA-------------E
AARAPPPT-RDVAAAFHLQKS-SNSSRETLENSS--------------SESSDAELAE----------------------
-KERGAEHRS-DDGNA------------------------------------------------------------DDP-
KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----MDLCKNS
YLPQFSGLMQPYDD-MYPA--YTYNNWTNKGLAPAPLSTKNFTF-FN---SM--SPLTSQSMFSA-PNSISS-MTMASGM
GHSAVPGMPT-PGLNNISNLNGIGTSG--INSAMSS------SACPYGP--PGSPYSVYR-----DTCNSSLATLRLKSK
QHPTF----GYSG---LQSP--GS---SLNACQYN---S-----
>Branchiostoma_floridae_PITX1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MDTLNDS----------------------LSLEQLVSVSPRRSQLTMAGMAPINNS
GTSTGSALDSTAVAGAHTSMAGTDSSMDSTHGSGA-----------ATVSAGSPVGKD----------------------
--SGSGSTPSTQDVTQD----------------------------------------------------------DDEMR
KRRRQRRQRTHFTSQQLQELEASFARNRYPDMATREEIAAWTNLTEARVRVWFKNRRAKWRKRERNQL-----GEF-KNG
FGPHFNGLMQPFDDGLYSGYSPAYNNWAA--KVPSPLTAKSFPWGLNSSGVPNVNPLSSQAMCFT-PPTTIG----TATT
MVPSMN-VGN--GLNSLSSLQNPTVA-----------------PCPYAS--PGQP-YAYR-----EQCNSSIAALRLKAK
QHSTS----VASS---FSYPSPVRQ-QTLSACQYA---VDRPV-
>Strongylocentrotus_purpuratus_PITX1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MNQLHHGPL--------------------STLEDLVASESAR--------------
---------VSAGIGSVAAQRPIDSAPQSRSSHHV-----------HSPTIDHNQDKP----------------------
--GVKGGHDDGDDSDND----------------------------------------------------------QDN-G
KKKRTRRQRTHFTSQQLQELEANFSRNRYPDLSTREEICAWCNLTETRVRVWFKNRRAKWRKRERNQL-----HEL-KNG
LGAGFNGLMQPFDDGLYSGYS--YNNWAAA-KTANHLGTKSFAWSLN---TVNPLSMTSQQMCFNPPPTTLS----STFS
AATPVNGVGQ--QLNSFNNAAAAAAVGA--------------ASYPYGSP-PGAPPYMYR-----EPCSNSIASLRLKAK
QHHSS----NVPG---LSYPVRQ-S-PTLSACQYAG--LNGSTT
>Homo_sapiens_PITX2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MNCMKGP--------LHLE-------------HRAAG-TKLSAVSSSS--------
CHHPQP-LAMASVLAPGQPRS-LDSSKHRLEVHT-------------ISDTSSPEAAE----------------------
-KDKSQQGKN-EDVGA------------------------------------------------------------EDPS
KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG
FGPQFNGLMQPYDD-MYPG--YSYNNWAAKGLTSASLSTKSFPF-FN---SMNVNPLSSQSMFSP-PNSISS-MSMSSSM
VPSAVTGVPG-SSLNSLNNLNNLSSPS--LNSAVPT------PACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK
QHSSF----GYAS---VQNP--AS---NLSACQYA---VDRPV-
>Mus_musculus_PITX2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MNCMKGP--------LPLE-------------HRAAG-TKLSAASSP-F-------
CHHPQA-LAMASVLAPGQPRS-LDSSKHRLEVHT-------------ISDTSSPEVAE----------------------
-KDKGQQGKN-EDVGA------------------------------------------------------------EDPS
KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG
FGPQFNGLMQPYDD-MYPG--YSYNNWAAKGLTSASLSTKSFPF-FN---SMNVNPLSSQSMFSP-PNSISS-MSMSSSM
VPSAVTGVPG-SSLNSLNNLNNLSSPS--LNSAVPT------PACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK
QHSSF----GYAS---VQNP--AS---NLSACQYA---VDRPV-
>Pan_troglodytes_PITX2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MNCMKGP--------LHLE-------------HRAAG-TKLSAVSSSS--------
CHHPQP-LAMASVLAPGQPRS-LDSSKHRLEVHT-------------ISDTSSPEAAE----------------------
-KDKSQQGKN-EDVGA------------------------------------------------------------EDPS
KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG
FGPQFNGLMQPYDD-MYPG--YSYNNWAAKGLTSASLSTKSFPF-FN---SMNVNPLSSQSMFSP-PNSISS-MSMSSSM
VPSAVTGVPG-SSLNSLNNLNNLSSPS--LNSAVPT------PACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK
QHSSF----GYAS---VQNP--AS---NLSACQYA---VDRPV-
>Macaca_mulatta_PITX2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MNCMKGP--------LHLE-------------HRAAG-TKLSAVSSSSS-------
CHHPQP-LAMASVLAPGQPRS-LDSSKHRLEVHT-------------ISDTSSPEAAE----------------------
-KDKGQQGKN-EDVGA------------------------------------------------------------EDPS
KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG
FGPQFNGLMQPYDD-MYPG--YSYNNWAAKGLTSASLSTKSFPF-FN---SMNVNPLSSQSMFSP-PNSISS-MSMSSSM
VPSAVTGVPG-SSLNSLNNLNNLSSPS--LNSAVPT------PACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK
QHSSF----GYAS---VQNP--AS---NLSACQYA---VDRPV-
>Rattus_norvegicus_PITX2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MNCMKGP--------LPLE-------------HRAAG-TKLSAASSP-F-------
CHHTQA-LAMASVLAPGQPRS-LDASKHRLEVHT-------------ISDTSSPEVAE----------------------
-KDKGQQGKN-EDVGA------------------------------------------------------------EDPS
KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG
FGPQFNGLMQPYDD-MYPG--YSYNNWAAKGLTSASLSTKSFPF-FN---SMNVNPLSSQSMFSP-PNSISS-MSMSSSM
VPSAVTGVPG-SSLNSLNNLNNLSSPS--LNSAVPT------PACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK
QHSSF----GYAS---VQNP--AS---NLSACQYA---VDRPV-
>Oryctolagus_cuniculus_PITX2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MNCMKGP--------LHLE-------------HRAAG-TKLSAASSSSS-------
CHHPPP-TAMASVLAPGQPRS-LDASKHRLEVHT-------------ISDTSSPEAAE----------------------
-KDKSQQGKN-EDVGA------------------------------------------------------------EDPS
KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG
FGPQFNGLMQPYDD-MYPG--YSYNNWAAKGLTSASLSTKSFPF-FN---SMNVNPLSSQSMFSP-PNSISS-MSMSSSM
VPSAVTGVPG-SSLNSLNNLNNLSSPS--LNSAVPT------PACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK
QHSSF----GYAS---VQNP--AS---NLSACQYA---VDRPV-
>Canis_familiaris_PITX2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MNCMKGP--------LHLE-------------HRAVG-TKLLATASPSS-------
CHHPQP-LAMASVLAPGQTRS-LDSAKHRLEVHT-------------ISDTSSPEAAE----------------------
-KDKSQQGKN-EDVGT------------------------------------------------------------EDPS
KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG
FGPQFNGLMQPYDD-MYPG--YSYNNWAAKGLTSASLSTKSFPF-FN---SMNVNPLSSQSMFSP-PNSISS-MSMSSSM
VPSAVTGVPG-SSLNSLNNLNNLSSPS--LNSAVPT------PACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK
QHSSF----GYAS---VQNP--AS---NLSACQYA---VDRPV-
>Bos_taurus_PITX2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MNCMKGP--------LHLE-------------HRAAG-TKLLAASSSSS-------
CHHPQP-LAMASVLAPGQARS-LDSSKHRLEVHT-------------ISDTPSPEAAE----------------------
-KDKSQQGKN-EDVGA------------------------------------------------------------EDPS
KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG
FGPQFNGLMQPYDD-MYPG--YSYNNWAAKGLTSASLSTKSFPF-FN---SMNVNPLSSQSMFSP-PNSISS-MSMSSSM
VPSAVTGVPG-SSLNSLNNLNNLSSPS--LNSAVPT------PACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK
QHSSF----GYAS---VQNP--AS---NLSACQYA---VDRPV-
>Gallus_gallus_PITX2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MSCMKDP--------LSLE-------------RLGAGNNKLCSSSPSSSSSSSS--
CHHQQPALAMATALAPGQARSSLEAAKHRLEVHT-------------ISDTSSPEAAE----------------------
-KEKSQQGKS-EDAGP------------------------------------------------------------EDPS
KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG
FGPQFNGLMQPYDD-MYPG--YSYNNWAAKGLTSASLSTKSFPF-FN---SMNVNPLSSQSMFSP-PNSISS-MSMSSSM
VPSAVTGVPG-SGLNSLNNLNNLSNPS--LNSAVPT------PACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK
QHSSF----GYAS---VQNP--AS---NLSACQYA---VDRPV-
>Taeniopygia_guttata_PITX2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MNCMKDP--------LSLE-------------RLGAG-NKLCSSSPSSSSSSSSSS
CHHHQPALVMATALAPGQARSSLESAKHRLEVHT-------------ISDTSSPEAAE----------------------
-KDKSQQSKN-EDAGP------------------------------------------------------------EDP-
KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG
FGPQFNGLMQPYDD-MYPG--YSYNNWAAKGLTSASLSTKSFPF-FN---SMNVNPLSSQSMFSP-PNSISS-MSMSSSM
VPSAVTGVPG-SSLNSLNNLNNLSNPS--LNSAVPT------PACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK
QHSSF----GYAS---VQNP--AS---NLSACQYA---VDRPV-
>Xenopus_tropicalis_PITX2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MNSMKEP--------LHLDHLVGSKLATASSHHQHHHQHHQQH-------------
-QQPQA-VTLVSMASSLGQRS--GECKARLEVHT-------------ISDTSSPEAAD----------------------
-KDKSHQSKN-EDSST------------------------------------------------------------DDPS
KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG
FGPQFNGLMQPYDD-MYPS--YSYNNWAAKGLTSASLSTKSFPF-FN---SMNVNPLSSQSMFSS-PNSISS-MSMSSGM
VPSAVTGVPG-SGLNSLNNLNNLSNPS--LNTAVPT------SACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK
QHSSF----GYAS---VQNP--GS---NLSACQYA---VDRPV-
>Danio_rerio_PITX2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MTSMKDP--------LSLD-------------HHHHN-HHVTG-------------
-SKHAP-LSMASSLQPL-QRS--VDSKHRLDVHT-------------VSDTSSPESVE----------------------
-KEK-GQSKN-EDSN-------------------------------------------------------------DDPS
KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG
FGPQFNGLMQPYDD-MYPS--YTYNNWAAKGLTSASLSTKSFPF-FN---SMNVNPLSSQTMFSP-PNSISS-MSMSSSM
VPSAVTGVPG-SSLNSLNNLNNLSNPS--LNSGVPT------PACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK
QHSSF----GYAS---VQNP--AS---NLSACQYA---VDRPV-
>Takifugu_rubripes_PITX2a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MNSMREP--------LNID-------------HHHLTGNKLTS-------------
-THHTA-LTMASSLQPL-QRS--VDAKHRVEVHT-------------VSDTSSPESVE----------------------
-KEK-IQNKN-DDSS-------------------------------------------------------------DDPS
KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG
FGPQFNGLMQPYED-MYPS--YTYNNWAAKGLTPASLSTKSFPF-FN---SMNVNPLSSQTMFSPAPNSIS---SMTSGM
VPSAVTGVPG-SSLNSLNNLNNLSNPS--LNSGVPT------SACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK
QHSSF----GYAS---VQNP--AT---NLSACQYA---VDRPV-
>Tetraodon_nigroviridis_PITX2a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MNSMREP--------LNID-------------HHHLTGNKLTS-------------
-THHTA-LTMASTLQPL-QRS--ADAKHRLEVHA-------------VSDTSSPESVE----------------------
-KEK-IQNKN-DDSS-------------------------------------------------------------DDPS
KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG
FGPQFNGLMQPYED-MYPS--YTYNNWAAKGLTPASLSTKSFPF-FN---SMNVNPLSSQTMFSPAPNSIS---SMTSGM
VPSAVTGVPG-SSLNSLNNLNNLSNPS--LNSGVPT------SACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK
QHSSF----GYAS---VQNP--AT---NLSACQYA---VDRPV-
>Gasterosteus_aculeatus_PITX2a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MNSMRDP--------LNID-------------HHHVTGNKLAS-------------
-AHPTA-LAMASTLQPL-QRS--VDSKHRLEVHT-------------VSDTSSPESVE----------------------
-KEK-NLNKN-DDSS-------------------------------------------------------------DDPS
KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG
FGPQFNGLMQPYED-MYPS--YTYNNWAAKGLTSASLSTKSFPF-FN---SMNVNPLSSQTMFSP-SNSIS---SMTSSM
VPSAVTGVPG-SSLNSLNNLNNLSNPS--LNSGVPT------SACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK
QHSSF----GYAS---VQNP--AT---NLSACQYA---VDRPV-
>Oryzias_latipes_PITX2a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------MNSMRNP--------LNTEQPH----------HLHLPGNKLTS-------------
-PQHTA-LAMASSLQPL-QRS--ADSKHRLEVQA-------------VSDTSSPESVE----------------------
-KEK-IQNKN-DDSS-------------------------------------------------------------DDPS
KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG
FGPQFNGLMQPYDD-MYPS--YTYNNWAAKGLTSASLSTKSFPF-FN---SMNVNPLSSQTMFSP-PNSIS---SMTSSM
VPAAVTGVPG-SSLNSLNNLNNLSNPS--LNSGVPT------PACPYAP--PTPPY-VYR-----DTCNSSLASLRLKAK
QHSSF----GYAS---VQNP--AT---NLSACQYA---VDRPV-
>Homo_sapiens_PITX3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MEFGLLSEAEARSPALSLSDAGTPHPQLPEHGC-----------KGQEHSDSEKAS----------------------
--------ASLPGGSP------------------------------------------------------------EDGS
LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQ-----AELCKGS
FAAPLGGLVPPYEE-VYPG--YSYGNWPPKALAPP-LAAKTFPFAFN---SVNVGPLASQPVFSP-PSSIA--ASMVPSA
AA-APGTVPGPGALQGLGGGPPGLAPAAVSSGAVSCPYAS-AAAAAAAA--ASSPY-VYR-----DPCNSSLASLRLKAK
QHASF----SYPA---VHGPPPAA---NLSPCQYA---VERPV-
>Mus_musculus_PITX3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MEFGLLGEAEARSPALSLSDAGTPHPPLPEHGC-----------KGQEHSDSEKAS----------------------
--------ASLPGGSP------------------------------------------------------------EDGS
LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQ-----AELCKGG
FAAPLGGLVPPYEE-VYPG--YSYGNWPPKALAPP-LAAKTFPFAFN---SVNVGPLASQPVFSP-PSSIA--ASMVPSA
AA-APGTVPGPGALQGLGGAPPGLAPAAVSSGAVSCPYAS-AAAAAAAA--ASSPY-VYR-----DPCNSSLASLRLKAK
QHASF----SYPA---VPGPPPAA---NLSPCQYA---VERPV-
>Pan_troglodytes_PITX3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MEFGLLSEAEARSPALSLSDAGTPHPQLPEHGC-----------KGQEHSDSEKAS----------------------
--------ASLPGGSP------------------------------------------------------------EDGS
LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQ-----AELCKGS
FAAPLGGLVPPYEE-VYPG--YSYGNWPPKALAPP-LAAKTFPFAFN---SVNVGPLASQPVFSP-PSSIA--ASMVPSA
AA-APGTVPGPGALQGLGGGPPGLAPAAVSSGAVSCPYAS-AAAAAAAA--ASSPY-VYR-----DPCNSSLASLRLKAK
QHASF----SYPA---VHGPPPAA---NLSPCQYA---VERPV-
>Macaca_mulatta_PITX3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MEFGLLSEAEARSPALSLSDAGTPHPQLPEHGC-----------KGQEHSDSEKAS----------------------
--------ASLPGGSP------------------------------------------------------------EDGS
LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQ-----AELCKGS
FAAPLGGLVPPYEE-VYPG--YSYGNWPPKALAPP-LAAKTFPFAFN---SVNVGPLASQPVFSP-PSSIA--ASMVPSA
AA-APGTVPGPGALQGLGGGPPGLAPAAVSSGAVSCPYAS--AAAAAAA--ASSPY-VYR-----DPCN-SLASLRLKAK
QHASF----SYPA---VHGPPPAA---NLSPCQYA---VERPV-
>Rattus_norvegicus_PITX3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MEFGLLGEAEARSPALSLSDAGTPHPPLPEHGC-----------KGQEHSDSEKAS----------------------
--------ASLPGGSP------------------------------------------------------------EDGS
LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQ-----AELCKGG
FAAPLGGLVPPYEE-VYPG--YTYGNWPPKALAPP-LAAKTFPFAFN---SVNVGPLASQPVFSP-PSSIA--ASMVPSA
AA-APGTVPGPGALQGLGGAPPGLAPAAVSSGAVSCPYAS-AAAAAAAA--ASSPY-VYR-----DPCNSSLASLRLKAK
QHASF----SYPA---VPGPPPAA---NLSPCQYA---VERPV-
>Oryctolagus_cuniculus_PITX3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MEFGLLSEAEARSPALSLSDAGTPHPPLPEHGC-----------KGQEHSDSEKAS----------------------
--------ASLPGGSP------------------------------------------------------------EDGS
LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQ-----AELCKGG
FAAPLGGLVPPYEE-VYPG--YSYGNWPPKALAPP-LAAKTFPFAFN---SVNVGPLASQPVFSP-PSSIA--ASMVPSA
AA-APGTVPGPGALQGLGGGPPGLAPAAVSSGAVSCPYAS-AAAAAAAA--ASSPY-VYR-----DPCNSSLASLRLKAK
QHASF----SYPA---VPGPPPAA---NLSPCQYA---VERPV-
>Canis_familiaris_PITX3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MEFGLLSEAEARSPALSLSDAGTPHPPLPEHGC-----------KGQEHSDWEKAW----------------------
--------ASLPGGSP------------------------------------------------------------EDGS
LKKKQRGQRTHFTSQQLQELEAPFQRNRYPDMSTREEIAVWTNLTEARVGVWFKNRRAKWRKRERSQQ-----AELCKGG
FAAPLGGLVPPYEE-VYPG--YSYGNWPPKALGPP-LAAKTFPFAFN---SVNVGPLASQPVFSP-PSSIA--ASMVPSA
AA-APGTVPGPGALQGLGGGPPGLAPAAVSSGAVSCPYAS-AAAAAAAA--ASSPY-VYR-----DPCNSSLASLRLKAK
QHASF----SYPA---VPGPPPAA---NLSPCQYA---VERPV-
>Bos_taurus_PITX3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MEFGLLSEAEARSPALSLSDAGTPHPPLPEHGC-----------KGQEHSDSEKAS----------------------
--------VSLPGGSP------------------------------------------------------------EDGS
LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQ-----AELCKGG
FAAPLGGLVPPYEE-VYPG--YSYGNWPPKALGPP-LAAKTFPFAFN---SVNVGPLASQPVFSP-PSSIS--ASMVPSG
AT-APGTVPGHGALQGLGGGPPGLAPAAVSSGAVSCPYAS-AAAAAAAA--ASSPY-VYR-----DPCNSSLASLRLKAK
QHASF----SYPT---VPGPPPAA---NLSPCQYA---VERPV-
>Pteropus_vampyrus_PITX3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MEFGLLSEAEARSPALSLSDAGTPHPPLPEHGC-----------KGQEHSDSEKAS----------------------
--------ASLPGGSP------------------------------------------------------------EDGS
LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQ-----AELCKGG
FAAPLGGLVPPYEE-VYPG--YSYGNWPPKALGPP-LTAKTFPFAFN---SVNVGPLASQPVFSP-PSSIA--ASMVPSA
AA-SPGTVPGPGALQGLGGGPPGLAPAAVSSGAVSCPYAS-AAAAAAAA--ASSPY-VYR-----DPCNSSLASLRLKAK
QHASF----SYPT---VPGPTPAA---NLSPCQYA---VERPV-
>Monodelphis_domestica_PITX3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MEFALLSEAEARSPALSLSDAGTPHPPHPEHSC-----------KGQEHSDTEKAP----------------------
--------PQLPGGSPT-----------------------------------------------------------EDGS
LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTTLTEARVRVWFKNRRAKWRKRERSQQ-----AELCKGG
FGASLGGLVPPYEE-LYPG--YSYGNWPPKALAPP-LAAKTFPFAFN---SVNVGPLASQPVFSP-PGSIATAASMVPTA
AAGAAGAVAGPGGLQGLGGGPAGLAPAAVSSGAVSCPYAT--AAAAAAA--ASSPY-VYR-----DPCNSSLASLRLKAK
QHASF----SYTA---VPGPAPAA---NLSPCQYA---VERPV-
>Ornithorhynchus_anatinus_PITX3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MDFNLLSEAEARSPALSLSDAGTPHP---EHGC-----------KGPEHSGPPPPV----------------------
--------AGLPTPGL------------------------------------------------------------GXXX
XKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQ-----AELCKGG
FGAQFSGLVPPYEE-MYPG--YSYGNWAPKGLAAA-PGAQELPF-FN---SVNVSPLASQPMFSP-PSSIA----SVPMP
AS--MASLQNLGGLQNLGGGP-GLAP-AVPSGAGSCPYASAAAAAAAAA--AAAPY-VYR-----DPCNSSLASLRLKAK
QHASF----SYPA---VPNAASAAG-ANLSPCQYA---VERPV-
>Gallus_gallus_PITX3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MDFNLLADAEARSPALSLSDSGTPQHEHSCKG--------------QDHSDTEKSQ----------------------
-------QNQTDDSNP------------------------------------------------------------EDGS
LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNS
FGAQFNGLMQPYDD-MYSS--YSYNNWATKGLATSPLSAKSFPF-FN---SMNVSPLSSQPMFSP-PSSIAS-MTMPSSM
VPSAVTGVPA-SSLNNLGNINNLNSPS--LNSAVSS------SACPYAS--TASPY-MYR-----DTCNSSLASLRLKAK
QHANF----TYPA---VQTA--AS---NLSPCQYA---VDRPV-
>Taeniopygia_guttata_PITX3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MDFNLLADTEARSPALSLSDSGTPQHEHSCKG--------------QDHSDTEKSQ----------------------
-------QNQTDDSNP------------------------------------------------------------EDGS
LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNS
FGAQFNGLMQPYDD-MYSS--YSYNNWATKGLASSPLSAKSFPF-FN---SMNVSPLSSQPMFSP-PSSITS-MTMPSSM
VPTAVTGVPA-PSLNNLGNINNLNSPS--LNSAVSS------SACPYAS--TASPY-MYR-----DTCNSSLASLRLKAK
QHANF----TYPA---VQTA--AS---NLSPCQYA---VDRPV-
>Anolis_carolinensis_PITX3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MEFNLLTDSEAHSPTLSLSESGTPQHEHSCKG--------------QEHSDTEKSQ----------------------
-------QNQTDDSNP------------------------------------------------------------EDGS
LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNS
FGAQFNGLMQPYDE-MYGG--YSYNNWATKGLAASTLSAKSFPF-FN---SMNVNPLSSQPMFST-PSSIGS-MPMPSSM
VPTTVTGVPG-PGLN------NLNSPG--LSSAVSS------STCPYAS--SASPY-MYR-----DTCNSSLASLRLKAK
QHANF----TYPA---VQTA--SS---SLSPCQYA---VDRPV-
>Xenopus_tropicalis_PITX3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MDFNLLTDSEARSPALSLSDSGTPQHDHSCKG--------------QEHSDTEKSQ----------------------
-------QNQTDDSNP------------------------------------------------------------EDGT
LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNS
FGAQFNGLMQPYDD-MYSG--YSYNNWATKGLATSPLSAKSFPF-FN---SMNVSPLSSQPIFSP-PNSIAS-MTMPSSM
VPSAVTGVPG-SSLNNLGNINNLNSPS--LNSAVSA------SACPYAS--TASPY-MYR-----DTCNSSLASLRLKAK
QHANF----TYPA---VQTP--AS---NLSPCQYA---VDRPV-
>Danio_rerio_PITX3a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MDFNLLTDSEARSPALSLSDSGTPQHDPGCKG--------------QDNSDTEKSH----------------------
-------QNHTDESNP------------------------------------------------------------EDGS
LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG
FGAQFNGLMQPYDD-MYSG--YSYNNWATKSLASSPLSAKSFPF-FN---SMNVSPLSSQPMFSP-PSSIPS-MNMASSM
VPSAVAGVPG-SGLNNLGNLNNLNSPT-LNSAAVSA------AACPYAT--TAGPY-MYR-----DTCNSSLASLRLKAK
QHANF----AYPA---VQNP--VS---NLSPCQYA---VDRPV-
>Tetraodon_nigroviridis_PITX3a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------ADTEKSQ----------------------
-------QNQLDESSA------------------------------------------------------------EDGS
LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG
FGAQFNGLMQPYDD-VYSG--YSYNNWAAKGLASSPLSAKSFPF-FN---SMNVSPLSSQSMFSP-PSSLPS-MNMASSM
VPSAVAGVPA-AGLNNLGNLNNLNAPTALNSVAVSA------ATCPYAP--SAGPY-MYR-----DTCNSSLASLRLKAK
QHANF----SYPA---VQNP--VA---NLSPCQYA---VDRPV-
>Oryzias_latipes_PITX3a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MDFNLLTDSGTRSPALSLSDAGTPQHDAGCKG--------------QDNSDTEKSH----------------------
-------QNQLDESSA------------------------------------------------------------EDGS
LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNG
FGAQFNGLMQPYDD-MYTG--YSYNNWATKSLASSPLSTKSFPF-FN---SMNVSPLSTQPMFSP-PSSIPS-MNMASSM
VPSAVAGVPA-AGLNNLGNLNNLNSPTALNSVAVTA------ATCPYAT--TASPY-MYR-----DTCNSSLASLRLKAK
QHTNF----AYPT---VQNP--VS---NLSPCQYA---VDRPV-