>Homo_sapiens_MXD1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------MAAAVRMNIQMLLEAADYLERRE------
-REAEHGYASMLPYNN----KDRDALKRRNKSKKNNSS-----------------------------------SRSTHNE
MEKN--RRAHLRLCLEKLKGLVPLGPESSRHTT-LSLLTKAKLHIKK-LEDCDRKAVHQIDQLQR-------EQRHLKRQ
LEKL--------------------------------------------------------------------------GI
ERIR------------MDSIGSTVSS-----------ERSDSDRE------------EIDVDVES--------------T
DYLTGDLDW-----------------------SSSSVSDSD--ERGSMQSLGSDEGYSSTSIKRIKLQDSHKA-CLGL--
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Pan_troglodytes_MXD1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------MAAAVRMNIQMLLEAADYLERRE------
-REAEHGYASMLPYNN----KDRDALKRRNKSKKNNSS-----------------------------------SRSTHNE
MEKN--RRAHLRLCLEKLKGLVPLGPESSRHTT-LSLLTKAKLHIKK-LEDCDRKAVHQIDQLQR-------EQRHLKRQ
LEKL--------------------------------------------------------------------------GI
ERIR------------MDSIGSTVSS-----------ERSDSDRE------------EIDVDVES--------------T
DYLTGDLDW-----------------------SSSSVSDSD--ERGSMQSLGSDEGYSSTSIKRIKLQDSHKA-CLGL--
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Macaca_mulatta_MXD1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------MAAAVRMNIQMLLEAADYLERRE------
-REAEHGYASMLPYNN----KDRDALKRRNKSKKNNSS-----------------------------------SRSTHNE
MEKN--RRAHLRLCLEKLKGLVPLGPESSRHTT-LSLLTKAKLHIKK-LEDCDRKAVHQIDQLQR-------EQRHLKRQ
LEKL--------------------------------------------------------------------------GI
ERIR------------MDSIGSTVSS-----------ERSDSDRE------------EIDVDVES--------------T
DYLTGDLDW-----------------------SSSSVSDSD--ERGSMQSLGSDEGYSSASIKRIKLQDSHKA-CLGL--
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Mus_musculus_MXD1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------MATAVGMNIQLLLEAADYLERRE------
-REAEHGYASMLPYS-----KDRDAFKRRNKPKKNSTS-----------------------------------SRSTHNE
MEKN--RRAHLRLCLEKLKGLVPLGPESSRHTT-LSLLTKAKLHIKK-LEDCDRKAVHQIDQLQR-------EQRHLKRR
LEKL--------------------------------------------------------------------------GA
ERTR------------MDSVGSVVSS-----------ERSDSDREEL----DVDVDVDVDVDVEG--------------T
DYLNGDLGW-----------------------SSS-VSDSD--ERGSMQSLGSDEGYSSATVKRAKLQDGHKA-GLSL--
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Rattus_norvegicus_MXD1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------MATAVGMNIQLLLEAADYLERRE------
-REAEHGYASMLPYSS----KDRDAFKRRNKPKKNSTS-----------------------------------SRSTHNE
MEKN--RRAHLRLCLEKLKGLVPLGPESSRHTT-LSLLTKAKLHIKK-LEDCDRKAVHQIDQLQR-------EQRHLKRR
LEKL--------------------------------------------------------------------------GA
ERTR------------MDSVGSVVSS-----------ERSDSDREELDVDVDVDVDVDVDVDVES--------------T
DYLNGDLGW-----------------------SSS-VSDSD--ERGSMQSLGSDEGYSSASVKRAKLQDGHKA-GPGL--
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Canis_familiaris_MXD1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------MAAAVRMNIQMLLEAADYLERRE------
-REAEHGYASMLPYSN----KDRDALKRRNKSKKNNSS-----------------------------------SRSTHNE
MEKN--RRAHLRLCLEKLKGLVPLGPESNRHTT-LSLLTKAKLHIKK-LEDCDRRAIHQIDQLQR-------EQRHLKRQ
LEKL--------------------------------------------------------------------------GI
ERIR------------MDSIGSTVSS-----------ERSDSDRE------------EVDVDVDVDVDGDAE------GA
DYLAGELDW-----------------------SSSGVSDSD--ERGSLRSAGSDEGYASSSRRRPAAPHARG----GL--
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Bos_taurus_MXD1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------MAAAVRMNIQMLLEAADYLERRE------
-REAEHGYASMLPYNN----KDRDALKRRSKSKKNNSS-----------------------------------SRSTHNE
MEKN--RRAHLRLCLEKLKGLVPLGPESNRHTT-LSLLTKAKLHIKK-LEDCDRKAIHQIDQLQR-------EQRHLKRQ
LEKL--------------------------------------------------------------------------GI
ERIR------------MDSTGSTVSS-----------ERSDSDRE------------EIDVDVES--------------T
DYLTGDLDW-----------------------SCSSVSDSD--ERGSMQSLGSDEGYSSSSVKRIKLQDSHKTTCLGL--
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Dasypus_novemcinctus_MXD1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---AEHGYASMLPYNN----KDRDALKRRNKSKKNNSS-----------------------------------SRSTHNE
MEKN--RRAHLRLCLEKLKGLVPLGPESNRHTT-LSLLTKAKLHIKK-LEDCDRKAIHQIDQLQR-------EQRHLKRQ
LEKL--------------------------------------------------------------------------GI
ERIR------------MDSIGSTVSS-----------ERSDSDR------------EEIDVDVES--------------T
DYLTGDLDW-----------------------SSSSVSDSD--ERGSTQSLGSDEGYSSSSIKRIKLQDNHKT-CLGL--
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Monodelphis_domestica_MXD1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------MAVAAAAVRMNIQLLLEAADYLERRE------
-REAEHGYASMLPYNN----KDRDALKRRSKSKKNSSS-----------------------------------SRSTHNE
MEKN--RRAHLRLCLEKLKGLVPLGPESNRHTT-LSLLTKAKLHIKK-LEDCDRKAVHQIDQLQR-------EQRHLKRQ
LEKL--------------------------------------------------------------------------GI
ERIR------------MDSIGSTVCS-----------ERSDSDR------------EEIDVDVES--------------T
DYLTGDLDW-----------------------SSSSVSDSD--ERGSMQSLCSDEGYSSSSIKRIKLQDNHKT-CLSL--
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Anolis_carolinensis_MXD1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------MATAAQVRENIRMLLEAAEFLERRE------
-REAEHGYASMLPYSA----NDRDAFKRRNKSKKNSSN-----------------------------------SRSTHNE
MEKN--RRAHLRLCLEKLKGLVPLGPESSRHTT-LSLLTKAKLHIKK-LEDCDRRAIHQIDQLQR-------EQRHLRRQ
LEKL--------------------------------------------------------------------------GI
ERIR------------TDSTGSAVSS-----------ERSDSDRGEMD----LQAEEDVDVDVES--------------T
DDLAGELDW-----------------------SSSSSSPSDSDERGSLQSLCSDEGYSSAGLQRIKPPDTLTA-CLGL--
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Danio_rerio_MXD1a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------MTAIEK-LQMLIEAAEYLDRRE------
-REAEHGYASMLPFTSN---KERDGLKRKIKSKKNCS------------------------------------SRSTHNE
MEKN--RRAHLRLCLERLKSLVPLGPESNRHTT-LSLLMRAKEHIKR-LEDSERKAQHTIDQLQR-------EQRHLRRR
LEQL--------------------------------------------------------------------------GV
ERTR------------MDSMGSTISS-----------DKSDSDQ------------EEVDVDVEG--------------T
DYLLGDLEW-----------------------STSSVSDS--DERGSLRSSCSDEGYSSASLRR--LANSQEN-SLVLAC
SL------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Takifugu_rubripes_MXD1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------MAAIGL-VQMLIEAAEYLDRRE------
-REAEHGYASMPPFISS---RERESLKRKSKSKKNTS------------------------------------SRSVHNK
LRSTL-KRAHLRLCLERLKSLVPLGPDANRHTT-LSLLMKAKDHIKK-LEESDRRAQHTMDQLQR-------EQRYLRRR
LEQL--------------------------------------------------------------------------GV
ERTR------------MDSTGSNLSS-----------DKSDSDQ------------EDLDVDVEG--------------T
DFMLGDLEW-----------------------STSSVSDSG-DERSSLRSSCSDEGYASASLQR--LQNTQET-AKQLGC
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Tetraodon_nigroviridis_MXD1a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------KMAAIGL-VQMLIEAAEYLDRRE------
-REAEHGYASMPPFISS---RERENLKRKSKSKKNTSN-----------------------------------SRSTHNE
MEKN--RRAHLRLCLERLKSLVPLGPDANRHTT-LSLLMKAKDHIKK-LEESDRRAQHTMDQLQR-------EQRYLRRR
LEQL--------------------------------------------------------------------------GV
ERTR------------MDSTGSNLSS-----------EKWESDQVLQPLSL-SASTEDLDVDVEG--------------T
DYMLGDLEW-----------------------STSSVSDSG-DERSSLR-------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Gasterosteus_aculeatus_MXD1a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------KMAAIGM-VQMLIEAAEYLERRE------
-REAEHGYASMPPFTSS---QERESLKRKSKSKKNTS------------------------------------SRSTHNE
MEKN--RRANLRLCLERLKSLVPLGPDANRHTT-LSLLMKARDHIKR-LEESDRRAQHTVEQLQR-------ERRHLRRR
LEQL--------------------------------------------------------------------------GV
ERTR------------MDSTGSNAS------------DKSDSDQVRLLFS----QTEDLDVDVEG--------------T
DYLLGDLEW-----------------------STSSVSDSG-DERGSLRSSCSDEGYSSASLLL--LQDTQER-AKQI--
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Oryzias_latipes_MXD1a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------RSTHNE
MEKN--RRAHLRLCLERLKSLVPLGPDASRHTT-LSLLMKAKDHIKR-LEEGDRKAQHTLDQLQR-------ERRHLRRR
LEQL--------------------------------------------------------------------------GV
ERTR------------MDSTGSTRS----------------SDNV----------TEDLDVDVEG--------------T
DYLLGDLEW-----------------------SISSVSDSG-DERSSLRSSCSDEGYASASLLR--LQDS----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Ciona_intestinalis_MXD1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------MLKGLQIGKVDLLLQAAEFLENKDKR----
DRETEHGYATPAYRIGQNFRTKVKTVRRSQNR-------------------------------------------TSHNE
LEKN--RRAHLRNCLDGLKAIVPLNQDATRHTT-LGLLTQARALIEN-LKHERQAVICEKTRLEE-------HGALLRHR
LHQLEIS-------------------------------------------------------------------------
RRRR-------------DSTGSSWSSG-----------RSESSND---------------SDKDE---------------
--EIIDVMDCS--------------------EACESLHALQSSVRPNLITINVPKALSLSTRVKQAKIAT----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Branchiostoma_floridae_MXD1
--------------------------MKANGLPYVGKRGTCLDDCVFGNDGTPDRDLPQHHLQGGCFLGRRPSAGFWYSL
AVCLETSVFHRRFLPCDAVHKEGCEVTVERQAVDEVGPPALEGVDGLSLTKRSKRTISLYSWKSKTLHEEYDMLTKKRKA
KAAMILIGMETRLASWVTIISPGPRDDLTRVAGGKQTQRTTTISLSKWRKTEISVKMMGIATLLEAAEFLERRER-----
--EAEHGYASTLPYPHEIPPRKRTKSSSSSRRSQASSR-------------------------------------TTHNE
LEKN--RRAHLRNCLERLKAIIPLSPETPRHTT-LGLLNKAKNEIRR-LEDENRRNSSSREQLFR-------QQRQLKRK
LEMLH---------------------------------------------------------------------------
RKIR------------HDSTGSMSDN------------RSDSSDE-------------IDVEFGGD-------------S
PTLTADSAYRS--------------------NSPGTSSDYAYGSNSPGTNSDFDENGSTSSDCGYTSSFIKQLS------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Strongylocentrotus_purpuratus_MXD1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------MEDVSILNIEQLLQAAEFLERRER-----
----EHGYASPYSHEANNK-RKHRVKRLNSNSSR-----------------------------------------STHNE
LEKN--RRAHLRTCLERLKEMVPLDGDMPRHTT-LGLLTNAKDFIVD-LEEKSEGFTSHKDQLCR-------EQRFLRRR
LDYL--QSTLH---------------------------------------------------------------------
-RQR------------QDSTGSSLASDD-------------SEKD--------------DVDVIG---------------
-YDS---DN----------------------------------RSIESDMNSSDGDLAVATKEIIITDL-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Caenorhabditis_elegans_MXD1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------MEQQLNLGHLLTAARLLDIGALDISSLDLGALTSTSSSPGSSSPAMFDLSNESELRSLFCGKL
KVDKKQSSCASNASTSSQPYCSSPPARKSSKHSR-----------------------------------------TAHNE
LEKT--RRANLRGCLETLKMLVPCVSDATRNTT-LALLTRARDHIIE-LQDSNAAQMKKLNDLRD-------EQDELVAE
LAQLQADEEVAQATS-----------------------------------------------------------QACQTL
SQSR------------PESRASSFTS------------TSSRDSP-----------CYLEYSPSSKP-----------MD
SHKPTIIDLYAEG---------------LIPRGPITFPRPLVYPHNVFDLMNLPPTPFDVSQFLPINLQV----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Homo_sapiens_MXD3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------MEPLASNIQVLLQAAEFLERRER-----
--EAEHGYASLCPHRSPGPIH-RRKKRPPQAPGAQDSG------------------------------------RSVHNE
LEKR--RRAQLKRCLERLKQQMPLGADCARYTT-LSLLRRARMHIQK-LEDQEQRARQLKERLRS-------KQQSLQRQ
LEQLRGLAGAA-------------------------------------------------------------------ER
ERLR------------ADSLDSSGLSS----------ERSDSDQGEC-------------PEAEG--------------L
CGPRGEPGLLT--------------------GPLPAQRSWR--WMWRAWCLGVRPSCCGASSPARSTATRTAAAPGYDVP
HPGRASALYS-CQAHLPGRSPPQAFRAARSHLLEWTKRTLVWEQVLPKHPAAGCQAGPLEGKGQDSSGPPWTPAGQAAWA
RAQAFGSAAPKGTGSLLGLFPSWTRPPAFASHKLYSIFIKSLFHNFPSIVLPNENGGTPNHRPTGRGNNISSHH------
--------------------------------------------------------
>Pan_troglodytes_MXD3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------RPPEAPGLSGIG------------------------------------RSVHNE
LEKR--RRAQLKRCLERLKQQMPLGADCARYTT-LSLLRRARMHIQK-LEDQEQRARQLKERLRS-------KQQSLQRQ
LEQLRGLAGAA-------------------------------------------------------------------ER
ERLR------------ADSLDSSGLSS----------ERSDSDQEEL------------EVDVES--------------L
VFGG-EAELLR--------------------G----------------FVAGQEHSYSHGGG----AWL-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Macaca_mulatta_MXD3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------MEPVASNIQVLLQAAEFLERRER-----
--EAEHGYASLCPHRSPGPIH-RRKKRPPQAPGAQDSG------------------------------------RSVHNE
LEKR--RRAQLKRCLERLKQQMPLGADCARYTT-LSLLRRARMHIQK-LEDQEQRARQLKERLRS-------KQQSLQQQ
LEQLRGLAGAA-------------------------------------------------------------------ER
ERLR------------TDSLDSSGLSS----------ERSDSDQGEC-------------PEAEG--------------L
CGPWGKPGLLI--------------------GPLPAQRSWR--WMWRAWCLGVRPSCCGASSPARSTATRTVAAPGYDVP
HPGVASLPSAHARPTCQAGALPKPLGLLGVTYWNGLKGPLCGNRCSPNTLLLAARQALWKGKGQDSSGPPWTPAGQAAWA
--------------------------------------------------------------------------------
--------------------------------------------------------
>Mus_musculus_MXD3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------MEPVASNIQVLLQAAEFLERRER-----
--EAEHGYASLCPHHSPGTVC-RRRKPPLQAPGALNSG------------------------------------RSVHNE
LEKR--RRAQLKRCLEQLRQQMPLGVDCTRYTT-LSLLRRARVHIQK-LEEQEQQARRLKEKLRS-------KQQSLQQQ
LEQLQGLPGAR-------------------------------------------------------------------ER
ERLR------------ADSLDSSGLSS----------ERSDSDQEDL------------EVDVES--------------L
VFGT-ETELLQ--------------------S----------------FSAGREHSYSHSTC----AWL-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Rattus_norvegicus_MXD3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------MEPVASNIQVLLQAAEFLERRER-----
--EAEHGYASLCPHHSPGTVC-RRRKAPLQAPGALNSG------------------------------------RHVHNE
LEKR--RRAQLKRCLEQLRQQMPLGVDHTRYTT-LSLLRRARMHIQK-LEEQEQQAQRLKEKLRS-------RQQSLQQQ
LEQLQGLLGVR-------------------------------------------------------------------ER
DRLR------------ADSLDSSGLSS----------ERFDSDQEDL------------EVDVES--------------L
VFGT-ETELLQ--------------------S----------------FSAGQEHSYSHSTG----TWL-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Canis_familiaris_MXD3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------MEPVASNIQVLLQAAEFLERRER-----
--EAEHGYASLYPHRSPGPVY-RRRKRSPQASGALDSG------------------------------------RSVHNE
LEKR--RRAQLKRCLEQLKQQMPLGADCARSTT-LSLLRWARVHIQK-LEEQEQQARRLKEKLRS-------KQQSLQRQ
LEWLRGLAGPG-------------------------------------------------------------------ER
ERPR------------ADSLDSSGLSS----------ERSDSDQEEV------------EVDVES--------------L
VFGG-EAELLR--------------------G----------------FSAGQEHSYSHSSS----TWL-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Bos_taurus_MXD3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------MEPVASNIQVLLQAAEFLERRER-----
--EAEHGYASLCPHRSPGPVH-RRRKRSPQAPGALDSG------------------------------------RSVHNE
LEKR--RRAQLKRCLEQLKQQMPLGADCVRYTT-LSLLRRARMHIQK-LEEQEQRARQLKEKLRS-------KQQSLRRQ
LEQLRGLGTVG-------------------------------------------------------------------ER
ERLR------------ADSLDSSGLSS----------ERSDSDQEEL------------EVDVES--------------L
VFGG-EAELLR--------------------G----------------FSAGQEHSYSHSGS----AWL-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Myotis_lucifugus_MXD3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------MESVASNIQVLLQAAEFLERRER-----
--EAEHGYASLFPHRSPGPVH-RKRKGSPQALGALDSG------------------------------------RSVHNE
LEKR--RRAQLKQCLEQLKQQMPLGADCARYTT-LSLLRRARMHIQK-LEEQEQRAQRLKEQLRS-------KQQSLQQQ
LEQLRAPVGAG-------------------------------------------------------------------ER
ERLR------------ADSLDSSGLSS----------ERSDSDQGEC-------------PEAEG--------------G
VGS--GPGLLT--------------------RPVPVQRNWR--WTWRAWCSGVRPSCCGASVRARSTATHT-AAPGYDPC
HPRACLCPQTTLCSTQPGRSPPQASRAAQS-LLEWTKRTLAWEPALSCPSAGCCSAS--EGRG-EGAWPPLSPARQAFFV
---ALGSVVPTGTGSLLG--PSPQGPLAFAP--YCTVFSLKGFHHFLPMVLPDENGETP-ATKWERGNEISHYN------
--------------------------------------------------------
>Monodelphis_domestica_MXD3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------MEQGASSIQVLLQAAEYLDRRER-----
--EAEHGYASLCPTHSLGPVN-RGR-RRPKAP--RDSL------------------------------------RSMHSE
LEKH--RRAQLRHCLEQLKQQMPLSTDCARYTT-LSLLRRARLHIQK-LEEQEQRARRLKDRLRS-------EQRSLRQR
LEQLQG--AGG-------------------------------------------------------------------EW
ERLR------------VDSLDSSGLSS----------ERSDTDQEEL------------EVDVES--------------L
VFGG-DAELLR--------------------G----------------FSTGQEHSYSHSGS----AWL-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Erinaceus_europaeus_MXD3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------------------------------SAHNE
LEKR--RRAQLKRCLEQLKQQMPLGADCARYTT-LSLLRRARVHIQK-LEEQEQRARRLKEKLRS-------QQQSLRRQ
LEQLRGPMGG----------------------------------------------------------------------
ERLR------------ADSLDSSGLCS----------ERSDSDQEEL------------EVDVES--------------L
VFGS-EAELLR--------------------G----------------FSAGQEHSYSHRGA----AWL-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Anolis_carolinensis_MXD3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------MELVASNIQVLLQAAEYLERRER-----
--EAEHGYASLSPHCGRDARQSRRRPKPRKAVKSLRFGF-----------------------------------RSAHNE
LEKH--RRAQLRHCLEQLKQQIPMNTEHSRYTT-LNLLHRARLHIKK-LEDQEEKARRQKERLRS-------EQRNLHQR
LEELLAHSS----------------------------------------------------------------------V
ERPR------------ADSLDSSRFSS----------EHSDSATEDA------------EVDVEG--------------L
AFISTEEDVVA--------------------A----------------ISTGQEHSYSNTNN----VWL-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Xenopus_tropicalis_MXD3
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------MEQLPSNLQVLLQAAEYVERRER-----
--EAEHGYASILPCDPATPGR-RKRQRTNSNP---DNV------------------------------------RSVHNE
LEKH--RRAQLRRCLEQLKQQVPLSMENSRHTT-LSLLHRAKQHIKK-LEDQELRAKSLKEKLRV-------EQQKLRQR
LKQLLPP-----------------------------------------------------------------------NT
ERIR------------TDSLDSSTLSS----------ERSDSDQEDL------------EVDVEG--------------I
ILSGNEGELFV--------------------S----------------FSAGLEHSYSTPAH----AWL-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Danio_rerio_MXD3a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------MEVNTCNIQVLLQAAEYLERRER-----
--EAEHGYASVLPFYSNGVSDKRKKQKSKSHSSPGNS-------------------------------------RSVHNE
LEKH--RRAQLRHCLEQLKQQVPLSSDSSRNTT-LNLLRQAQLHIKK-LQEQDERAKLLKDRLRW-------EQRELRTR
LEKLQG------------------------------------------------------------------------GS
ERMR------------NDSLGSA-VSS----------ERSDSEREDV------------EIDVES--------------M
VWTL-EADALG--------------------SS----------------HAGVDHSYSTSDH----AWL-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Takifugu_rubripes_MXD3a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------MDS-VYNIQVLLRAAEFLERKER-----
--EAEHGYASVLPLSPD-HPDKRSKQKSKKMSGGGNSC------------------------------------RVVHNE
LEKN--RRAQLRQCLEQLKKQVPLSSDSVRNTT-LNLLRRAQLHIKK-LQEQDELAQQMKGRLRW-------QQRELRVR
LEQLQR------------------------------------------------------------------------GS
ERMR------------NDSQGSS-MSS----------ERSDSDREDV------------EVDVES--------------I
VFDCVDSEGLS--------------------IT----------------HADADHCYSSLDK----SWL-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Tetraodon_nigroviridis_MXD3a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------MDG-VYNIQVLLRAAEFLERRER-----
--EAEHGYASVLPLSPD-HPDKRSKQKNKKMSGGGN--------------------------------------RVVHNE
LEKN--RRAQLRQCLEQLKKQVPLSPDSVRNTT-LNLLRRAQLHIKK-LQEQDELAERLKGRLRW-------QQRELRVR
LEQLQR------------------------------------------------------------------------GS
ERMR------------NNSQGSS-MSS----------ERSDSDREDV------------EVDVES--------------I
MFDCVDSDGLS--------------------IS----------------HMDADHCYSSPDK----SWL-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Gasterosteus_aculeatus_MXD3b
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------MDGNICNIQVLLRAAEFLERRER-----
--EAEHGYASLQPLSPD-PSDKRSKQKSKKTSSGGN--------------------------------------------
------RRAQLRECLEQLKKQVPLSSDSMRNTT-LNLLRRAQLHIKK-LKEQDQRAEQLKGRLRW-------EQRELRVR
LEQLQR------------------------------------------------------------------------GS
ERMR------------NDSHGST-MSS----------ERSDSDREDV------------EVDVES--------------I
VFDCLDSDGLS--------------------IT----------------HTGADHCYSSMDK----AWL-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Oryzias_latipes_MXD3a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------MEGHICNIQVLLRAAEFLERRER-----
--EAEHGYALVLPISSP-HSDKTGKQKSKKISVGGNSSN-----------------------------------RSVHNE
LEKNRCRRAQLRHCLEQLKKQVPLSSDSSRNTT-LSLLRQAQLHIKK-LQEQDERAEQLKGRLLW-------EQRELRIR
LEQLER------------------------------------------------------------------------GT
ERMR------------NNSHGST-MSS----------ERSDSDTEDV------------EVDVES--------------I
VFEC-DSDELS--------------------IT----------------HTGADHCYSSMDK----AWL-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Homo_sapiens_MXD4
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------MELNSLLILLEAAEYLERRDR-----
--EAEHGYASVLPFDGDFAREKTKAAGLVRKAP---NNR------------------------------------SSHNE
LEKH--RRAKLRLYLEQLKQLVPLGPDSTRHTT-LSLLKRAKVHIKK-LEEQDRRALSIKEQLQQ-------EHRFLKRR
LEQLSVQS-----------------------------------------------------------------------V
ERVR------------TDSTGSAVST-------------DDSEQ---------------EVDIEG--------------M
EFGPGELD------------------------SVGSSSDAD--DHYSLQSGTGGDSGFGPHCRRLGRPALS---------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Pan_troglodytes_MXD4
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------NR------------------------------------SSHNE
LEKH--RRAKLRLYLEQLKQLVPLGPDSTRHTT-LSLLKRAKVHIKK-LEEQDRRALSIKEQLQQ-------EHRFLKRR
LEQLSVQS-----------------------------------------------------------------------V
ERVR------------TDSTGSAVST-------------DDSEQ---------------EVDIEG--------------M
EFGPGELD------------------------SVGSSSDAD--DHYSLQSGTGGDSGFGPHCRRLGRPALS---------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Macaca_mulatta_MXD4
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------MELNSLLILLEAAEYLERRDR-----
--EAEHGYASVLPFDGDFTREKTKAASLVRKAP---NNR------------------------------------SSHNE
LEKH--RRAKLRLYLEQLKQLVPLGPDSTRHTT-LSLLKRAKVHIKK-LEEQDRRALSIKEQLQQ-------EHRFLKRR
LEQLSVQS-----------------------------------------------------------------------V
ERVR------------TDSTGSAVST-------------DDSEQ---------------EVDIEG--------------M
EFGPGELD------------------------SVGSSSDAD--DHYSLQSGSGGDSGFGPHCRRLGRPALS---------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Mus_musculus_MXD4
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------MELNSLLLLLEAAEYLERRDR-----
--EAEHGYASVLPFDGDFARKKTKTAGLVRKAP---NNR------------------------------------SSHNE
LEKH--RRAKLRLYLEQLKQLVPLGPDSTRHTT-LSLLKRAKMHIKK-LEEQDRRALSIKEQLQR-------EHRFLKRR
LEQLSVQS-----------------------------------------------------------------------V
ERVR------------TDSTGSAVST-------------DDSEQ---------------EVDIEG--------------M
EFGPGELD------------------------SAGSSSDAD--DHYSLQSSGCSDSSYGHPCRRPGCPGLS---------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Canis_familiaris_MXD4
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------VGEVGSPGARGGRRAEPAGEGRAAAAAVTESAGGRGMKRNSLLILLEAAEYLERRDR-----
--EAEHGYASVLPFDGDFARKKTKAAGLVRKAP---NNR------------------------------------SSHNE
LEKH--RRAKLRLYLEQLKQLVPLGPDSTRHTT-LSLLKRAKMHIKK-LEEQDRRALSIKEQLQR-------EHRFLKRR
LEQLSMQS-----------------------------------------------------------------------L
ERVR------------TDSTGSAVST-------------DDSEQ---------------EVDVEG--------------M
EFGPGELD------------------------SVGSSSDVD--DHYSLQSGGCSDGGYGPPCRRPGRPGLS---------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Bos_taurus_MXD4
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------MELNSLLILLEAAEYLERRDR-----
--EAEHGYASVLPFDGDFARKKTKAAGLVRKAP---NNR------------------------------------SSHNE
LEKH--RRAKLRLYLEQLKQLVPLGPDSTRHTT-LSLLKRAKMHIKK-LEEQDRRALSIKEQLQR-------EHRFLKRR
LEQLSAQS-----------------------------------------------------------------------L
ERVR------------TDSTGSAVST-------------DDSEQ---------------EVDVEG--------------M
EFGPGELD------------------------SVGSGSDVD--DHYSLRGGGCSHGSFGPPCRRPGRPGLS---------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Monodelphis_domestica_MXD4
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------MEWNSLLLLLEAAEYLERRDR-----
--EAEHGYASVLPFDSEYSRKKTKTA-ALARKSQ--NNR------------------------------------SSHNE
LEKH--RRAKLRLYLEQLKQLVPLGPDSTRHTT-LSLLKRARMHIKK-LEEQDRKALNVKEQLQR-------EHRYLKRR
LEQLSVQG-----------------------------------------------------------------------M
ERVR------------TDSTGSTIST-------------D-SEQ---------------EVDIEG--------------M
EFTPGEMD------------------------SVGSASDAD--DHYSLGSGSSDS--SYSHSRRLS-GRLS---------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Gallus_gallus_MXD4
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------MELNSLLILLEAAEYLERRDR-----
--EAEHGYASVLPFDSDYSRKKTKAG-SMARKSP--NNR------------------------------------SSHNE
LEKH--RRAKLRLYLEQLKQLVPLGPDSTRHTT-LSLLKRAKMHIKK-LEEQDRKALNIKEQLQR-------EHRYLKRR
LEQLSVQG-----------------------------------------------------------------------M
ERIR------------TDSMGSTIST-------------D-SEQ---------------EVDIEG--------------M
EFTPGEMD------------------------SIGSASDAE--DHYSLQSGSSDG--GYSHSRRLN-ARLS---------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Taeniopygia_guttata_MXD4
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------MELNSLLILLEAAEYLERRDR-----
--EAEHGYASVLPFDSDYSRKKTKAG-TMARKSQ--NNR------------------------------------SSHNE
LEKH--RRAKLRLYLEQLKQLVPLGPDSTRHTT-LSLLKRAKMHIKK-LEEQDRKALNIKEQLQR-------EHRYLKRR
LEQLSVQG-----------------------------------------------------------------------M
ERIR------------TDSMGSTIST-------------D-SEQ---------------EVDIEG--------------M
EFTPGEMD------------------------SIGSASDAE--DHYSLQSGSSDG--GYTHSRRLN-ARLS---------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Anolis_carolinensis_MXD4
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------MEWNSLLMLLEAAEYLERRER-----
--EAEHGYASVLPFESDHPGRKTKFG-----KSP--NNR------------------------------------SSHNE
LEKH--RRAKLRLYLEELKQLVPLGADSTRHTT-LSLLKRAKMHIKK-LEEQDRKALNIKEQLQR-------EHRYLKRR
LEQLSMQG-----------------------------------------------------------------------L
ERIR------------TDSLGSTLST-------------D-SEQ---------------EVDIEG--------------I
EFTAAGMD------------------------NSGSTSD----AEDSFQGSSSDG--GYTYSLRVN-TRLL---------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Takifugu_rubripes_MXD4
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------ESQPRCLNIGILLEAAEYLERRDR-----
--EAEHGYASVLPYTSDFSRKKTKASPMS-RKTQ--NNR------------------------------------SSHNE
LEKH--RRAKLRLYLEQLKKLVPLGPDSTRHTT-LSLLKRAKMHIKK-LEEQDRKALNTKEQLQR-------EHRYLKRR
LEQLSVSGS----------------------------------------------------------------------V
ERIR------------TDSMGSTIST-------------D-SEQGSLSLV-------NTEVDIEG--------------M
EFTPVEAD------------------------SVDSISDGEEEDHYSLQSSSSDTSYTATHSHRLQ--------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Tetraodon_nigroviridis_MXD4a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------MELNSLLILLEAAEYLERRDR-----
--EAEHGYASVLPYTNDFSRKKTKASPMS-RKTQ--NNR------------------------------------SSHNE
LEKH--RRAKLRLYLEQLKKLVPLGPDSTRHTT-LSLLKRAKMHIKK-LEEQDRKALNTKEQLQR-------EHRYLKRR
LEQLSVSGS----------------------------------------------------------------------V
ERIR------------TDSMGSTIST-------------D-SEQ---------------EVDIEG--------------V
EFTPVEAD------------------------SVDSISD----DQYGLQSSSSDTSYTATHSHRLQ-PHHC---------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Gasterosteus_aculeatus_MXD4
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------MELNSLLILLEAAEYLERRDR-----
--EAEHGYASVLPYRSDFSTKKTKASAIS-RKPL--NNR------------------------------------SSHNE
LEKHS-RRAKLRLYLEQLKKLVPLGPDSTRHTT-LSLLKRAKMHIKK-LEEQDKKALNTKEQLQR-------EHRYLKRR
LEQLSVSGS----------------------------------------------------------------------V
ERIR------------TDSLGSTIST-------------D-SEQ---------------EVDIEG--------------I
EFTPVEAD------------------------SVDSISD----DHYSLQSSSSDTSYTATHSHRLQ-PHHC---------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Oryzias_latipes_MXD4a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------MELNSLLILLEAAEYLERRDR-----
--EAEHGYASVLPYTNDFSRKKTKTSTMS-RKTQ--NNR------------------------------------SSHNE
LEKH--RRAKLRLYLEQLKKLVPLGPDSTRHTT-LSLLKRAKMHIKK-LEEQDKKALNVKEQLQR-------EHRYLKRR
LEQLSLSGS----------------------------------------------------------------------V
ERIR------------TDSMGSTIST-------------D-SEQ---------------EVDIEG--------------M
EFTPVEAD------------------------SVDSISD----DHYSLQSSSSDTSYTATHSHRLQ-PHHC---------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Homo_sapiens_MXI1
--------------------------------------------------------------------------------
---------------------------------------------------MGKRGRPRKEARCEGAGLA----------
----PAAPPAVPPAVAAP--QPPALPEDPAGAKPRCPFSDIFNTSENSMEKHINTFLQNVQILLEAASYLEQIE----KE
NKKCEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNT----------------------------STANRSTHNE
LEKN--RRAHLRLCLERLKVLIPLGPDCTRHTT-LGLLNKAKAHIKK-LEEAERKSQHQLENLER-------EQRFLKWR
LEQLQGPQE----------------------------------------------------------------------M
ERIR------------MDSIGSTISS-----------DRSDSERE------------EIEVDVES--------------T
EFSHGEVDN----------------------ISTTSISDID--DHSSLPSIGSDEGYSSASVKLSFTS------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Pan_troglodytes_MXI1
--------------------------------------------------------------------------------
---------------------------------------------------MGKRGRPRKEARCEGAGLA----------
----PTAPPAVPPAAAAP--QPPALPEDPAGAKPRCPFSDIFNTSENSMEKHINTFLQNVQILLEAASYLEQIE----KE
NK-------------------------------------------------------------------------STHNE
LEKN--RRAHLRLCLERLKVLIPLGPDCTRHTT-LGLLNKAKAHIKK-LEEAERKSQHQLENLER-------EQRFLKWR
LEQLQGPQE----------------------------------------------------------------------M
ERIR------------MDSIGSTISS-----------DRSDSERE------------EIEVDVES--------------T
EFSHGEVDN----------------------ISTTSISDID--DHSSLPSIGSDEGYSSASVKLSFTS------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Macaca_mulatta_MXI1
--------------------------------------------------------------------------------
---------------------------------------------------MGKRGRPRKEARCEGAGLA----------
----PSAPPVVPPAAAAP--QPPALPEEPAGAKPRCPFSDIFNTSENSMEKHINTFLQNVQILLEAASYLEQIE----KE
NKKCEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNT----------------------------STANRSTHNE
LEKN--RRAHLRLCLERLKVLIPLGPDCTRHTT-LGLLNKAKAHIKK-LEEAERKSQHQLENLER-------EQRFLKWR
LEQLQGPQE----------------------------------------------------------------------M
ERIR------------MDSIGSTISS-----------DRSDSERE------------EIEVDVES--------------T
EFSHGEVDN----------------------ISTTSISDID--DHSSLPSIGSDEGYSSASVKLSFTS------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Mus_musculus_MXI1
--------------------------------------------------------------------------------
---------------------------------------------------MGKRGRPRKEARCEGAGLV----------
----PVAPPAMPPAAAAP--QPPAQPEEPAGAKPRCPFSDIFNTSENSMEKHINTFLQNVQILLEAASYLEQIE----KE
NKKCEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNT----------------------------STANRSTHNE
LEKN--RRAHLRLCLERLKVLIPLGPDCTRHTT-LGLLNKAKAHIKK-LEEAERKSQHQLENLER-------EQRFLKRR
LEQLQGPQE----------------------------------------------------------------------M
ERIR------------MDSIGSTISS-----------DRSDSERE------------EIEVDVES--------------T
EFSHGEADS----------------------VSTTSISDLD--DHSSLQSVGSDEGYSSASVKLSFAS------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Rattus_norvegicus_MXI1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------MERVRMINVQRLLEAAEFLERR----ERE
---CEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNT----------------------------STANRSTHNE
LEKN--RRAHLRLCLERLKVLIPLGPDCTRHTT-LGLLNKAKAHIKK-LEEAERKSQHQLENLER-------EQRFLKRR
LEQLQGPQE----------------------------------------------------------------------M
ERIR------------MDSIGSTISS-----------DRSDSERE------------EIEVDVES--------------T
EFSHGEVDN----------------------ISTTSISDID--DHSSLQSIGSDEGYSSASVKLSFTS------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Canis_familiaris_MXI1
--------------------------------------------------------------------------------
---------------------------------------------------MGKRGRPRKEARCEGAGLA----------
----PAAP----PAVAAP--QPPAQPEEPAGAKLRCPFSDIFNTSENSMEKHINTFLQNVQILLEAASYLEQIE----KE
NKKCEHGYASTFPSMPSPRLQHSKPPRRLSRAQKHSTGSSNT----------------------------STANRSTHNE
LEKN--RRAHLRLCLERLKVLIPLGPDCTRHTT-LGLLNKAKAHIKK-LEEAERKSQHQLENLER-------EQRFLKRR
LEQLQGSQE----------------------------------------------------------------------M
ERIR------------MDSIGSTISS-----------DRSDSERE------------EIEVDVES--------------T
EFSHGEVDN----------------------ISTTSISDID--DHSSLQSIGSDEGYSSASVKLSFTS------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Bos_taurus_MXI1
--------------------------------------------------------------------------------
---------------------------------------------------MGKRGRPRKEARCEGAGLA----------
----PAAP----PAVTAP--QPPAQPEEPAGAKLRCPFSDIFNTSENSMEKHINTFLQNVQILLEAASYLEQIE----KE
NKKCEHGYASTFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNT----------------------------STANRSTHNE
LEKN--RRAHLRLCLERLKVLIPLGPDCTRHTT-LGLLNKAKAHIKK-LEEAERKSQHQLENLER-------EQRFLKRR
LEQLQGPQE----------------------------------------------------------------------M
ERIR------------MDSIGSTISS-----------DRSDSERE------------EIEVDVES--------------T
EFSHGEVDN----------------------ISTTSISDID--DHSSLQSIGSDEGYSSASVKLSFTS------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Myotis_lucifugus_MXI1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------RRAHLRLCLERLKVLIPLGPDCTRHTT-LGLLNKAKAHIKK-LEEAERKSQHQLEHLER-------EQRFLKRR
LEQLQGPQE----------------------------------------------------------------------M
ERIR------------MDSIGSTISS-----------DRSDSERE------------EIEVDVES--------------T
EFSHGEVDN----------------------ISTTSISDID--DHSSLQSIGSDEGYSSASVKLSFTS------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Monodelphis_domestica_MXI1
--------------------------------------------------------------------------------
---------------------------------------------------MGKRGRPRKEARCGEEDGPAASSEPQTQP
QPQP--------------------QPGAPVAAQLRCPFSDIFNTSESSVEKHINTFLQNVQILLEAASYLEQI----EKE
NKKCEHGYASAFPSVPSPRMQHSKPPRRLSRAQKHNSGSSNT----------------------------STANRSTHNE
LEKN--RRAHLRLCLERLKVLIPLGPDCTRHTT-LGLLNKAKAHIKK-LEEAERKSQHQLENLER-------EQRFLKRR
LEQLQGPQE----------------------------------------------------------------------M
ERIR------------MDSIGSTISS-----------DRSDSERE------------EIEVDVES--------------T
EFSHGEVDN----------------------ISTTSISDID--DHSSLQSIGSDEGYSSASVKLSFTS------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Ornithorhynchus_anatinus_MXI1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------MVSHAHVSLTYTCFWFLSHHLCFIPLRTRFKKTSGLPGAGEFFLNRYPLLFPS
RAECEHGYASTFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNT----------------------------STANRSTHNE
LEKN--RRAHLRLCLERLKVLIPLGPDCTRHTT-LGLLNKAKAHIKK-LEEAERKSQHQLENLER-------EQRFLKRR
LEQLQGPQE----------------------------------------------------------------------M
ERIR------------MDSIGSTISS-----------DRSDSERE------------EIEVDVES--------------T
EFSHGEVDN----------------------ISTTSISDID--DHSSLQSIGSDEGYSSASVKLSFAS------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Gallus_gallus_MXI1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------MEQVQLINIQRLLEAAEYLERRER-----
--ECEHGYASTFPSAPSPGLQDPKPTRRLSRARKHSGSGSSA----------------------------SIANRSTHNE
LEKN--RRAHLRLCLERLKVLIPLGPDCTRHTT-LGLLNKAKAHIKK-LEEVERRSQHQLENLER-------EQRFLKRR
LEQLQGPQE----------------------------------------------------------------------I
ERIR------------MDSIGSTISS-----------DRSDSERE------------EIEVDVES--------------T
EFSHGEVDN----------------------ISTTSISDID--DHSSLQSIGSDEGYSSASVKLSFAS------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Anolis_carolinensis_MXI1
--------------------------------------------------------------------------------
---------------------------------------------------MGKRGRPRKELRGEG--------------
---------------------------------AAAAAAAVVVEEEKDSMERINTFLQNVQILLEAASYLKQIE----KE
NKKCEHGYASTFPSMPTLGLQDPKPPQRLSRARKHSSGGSST----------------------------GTANRSTHNE
LEKN--RRAHLRLCLERLKVLIPLGPDCTRHTT-LGLLNKAKAHIKK-LEDADRRSQHQLENLER-------EQRFLKRR
LEQLQGSQD----------------------------------------------------------------------I
ERIR------------MDSTGSTISS-----------DRSDSERE------------EIEVDVES--------------T
EFSHGDVDD----------------------ISTTSTSDID--DHSSLQSIGSDEGYSSASVKLSFTS------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Danio_rerio_MXI1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--MVRSERQQTEVKAEDLFLESETSLDQQDFEMSTCPFNDVFNSTDS--S-MINTFLKNVQVLLEAASYIESAE----RK
DGKCEHGYASTFPSIQHSSYQRQRKFRNKKCNNNHYR--------------------------------------STHNE
LEKN--RRAHLRLCLERLKTLIPLGPECSRHTT-LGLLNKAKAHIKK-LEEADRKSRYQLESLER-------EQRHLRRR
LDLLRDGGG----------------------------------------------S---------------------LEA
ERIR------------TDSVGSTPCSERS--------DRSDSDQE------------EMEVDVES--------------T
EFSHGELDS----------------------VSTASTSDLD--DHSSLQSTASDEGYSSCSIKLAFSS------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Takifugu_rubripes_MXI1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------SESDASTDQQNFAEMSDYSLGDVLYSKCSAMD-QIGTFMRNVQVLLDAANYLENVE----KS
SGKYEHGYASSYPTTRSEHHQNQRKFKNRKLDSTHNS-------------------------------------RSAHNE
LEKN--RRAHLRLCLERLKSLIPLGPDCSRHTT-LGLLNKAKAHIKK-LEETDRRSQHQLETLER-------EQRHLQRQ
LAQLQPHG------------------------------------------------------------------------
ERVR------------TDSLGSRVDS-----------ERSESDRE------------EIEVDVES--------------T
EFSHGEMDS----------------------VSTSGASDLD--DHSSRQSSASDEGYSTCSVKVAFSA------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Tetraodon_nigroviridis_MXI1a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------MSDCSLSDVLYSKCSAMD-PIGTFMKNVQVLLDAANYLENIE----KS
SGKYEHGYASSYPTARSAHHQNQRKFRKGKLDSTHN--------------------------------------RSAHNE
LEKN--RRAHLRLCLERLKSLIPLGPDCSRHTT-LGLLNKAKAHIKK-LEEVDRRSQHQLETLER-------EQRHLQRQ
LAQLQTHG------------------------------------------------------------------------
ERVR------------MDSLGSREDS-----------DRSESDRE------------EIEVDVES--------------T
EFSHGELDS----------------------VSTSGASDLD--DHSSRQSSTSDEGYSTCSLKVAFSA------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Tetraodon_nigroviridis_MXI1b
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------CAFNDVFDSRDSDME-QINTFLTNVQVLLEAARFLEGTD----RK
DGKCEHGYASTFPSNQNTNYQRQRKFRNKKFSSNHNR-TENPL---------------------------LCLHRSTHNE
LEKNS-RRAPLRLCLERLKGLIPLGPDCTRHTT-LGLLNKAKAHIKK-LEETDRKSQYQLDSLER-------EQRHLKRQ
LELLGAGGG--------------------------------------------------------------------GEG
ERTR------------SDSLGSALGS-----------ERSDSDQA------------EVEVDVES--------------V
EFSHGELDS----------------------ESSASTSDLD--DHSSLQSLASDEGYSSCSVKLSFPS------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Gasterosteus_aculeatus_MXI1a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------FFSVSKCSAMD-RIGTFTKTVQVLLDAANYLENVE----KS
YGKCEHGYASTYPETQTAPQLKQRKSKNRKSDNIHN--------------------------------------RSAHNE
LEKNS-RRAHLRLC-ERLKSLIPLGPDCSRHTT-LGLLNKAKAHIKK-LEELDRRSLHQLETLER-------EQRHLQRQ
LSQLQTHGD----------------------------------------------------------------------R
ERVC------------TDSQGSHVDS-----------G-SDRGAE------------EIEIDVES--------------T
EFSHGEMDS----------------------VSTSGTSDLD--DLSSQQSSASDEGYSTCSVKLAFSA------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------
>Oryzias_latipes_MXI1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------QHPLLAAPQSPPTNTEPSVLDPQDLDESSCGFNDVFDSRDPRME-QINTFLKNVHVLLEAARFLESAD----RK
DGKCEHGYASTCPSDQSTSYQRTRRFRNKKFNNNHNRSSVITL---------------------------SFFFRSTHNE
LEKN--RRAHLRLCLERLKALIPLGPDCTRHTT-LGLLTKAKAHIKK-LEEADRKSQNQLQSLER-------EQRHLQLQ
LELLRGGGGGTQSN-----------------------------------------P---------------------GEG
ERIR------------MNSVGSTLCS-----------DRSDSDQE------------EIEVDVES--------------T
EFSHGELDS----------------------VSTASTSDLD--DHSSLQSMASDEGYSSCSVKLAFSS------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------