>Homo_sapiens_GPR125
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------MEPPGRRRGRAQPPLLLPLSLLALLALLGGGGGGGAAALPAGCKHDG---RPRGAGR-------AAG
AAEGKVVCSSLEL-------AQVLPPDTLPNRT--VTLILSNNKISELKNGSF---------------------------
---SGLSLLERLDLRNNLISSIDPGAFWGLSS---LKRL-DLTNNRIGCLNADIFRG-LTNLVRLNLSG-----------
------------------------------------NLFSSLSQGTFDYLA------------------------SLRSL
--------------------------------------------------------------------------------
--------------------------------------------------------EFQTEYLLCDCNILWMHRWVKE-K
NITVR-DTRCVYPKSLQAQPVTGVKQELLTCDPPLELPSFYMTPSHRQVVFEGDSLP---FQCMASYIDQ----------
---------DMQVLWYQDGR------------IVETDESQGIFVEKNMIHNCSLIASALTISNIQAGSTGNWGCHVQTKR
GNNTRTVDIVVLESS----------------------AQYCPPERVVNNKGD---FRWPRTLAGITAYLQCTRNTHGSGI
YPGNP-----------QDERKAWRRCD--RGGFWADDDYSRCQYANDVTRVLYMFNQMPLN-------------------
----LTNAVATARQLLAYTVEAANF---SDKMDVIFVAEMIEKFGRFTKEEKSK-ELGDVMVDIASNIMLADERVLWLAQ
REAKACSRIVQCLQRIATYRLAGGA--------HVYSTYSPNIALEAYVIKST---GFTGMTCTVFQKVAASDRTGLS-D
YGRR---DPEGNLDKQLSFKCNVSNTFSSLALKN---TIVEASIQLPPSLFSPKQ----KRELRPTDDSLYKLQLIAFRN
GKLFPATG---NSTNLADDGKRRTVVTPVILTKID-GVNVDTHHIPVNVT----------------LRRIAHG----ADA
VAARWDFDLLNGQGGWKSDGCHILYSDENITTIQCYSLSNYAVLMDLTGSELYTQ------------AASLLHP--VVYT
TAIILLLCLLAVIVSYIYH-----HSLIRISLKSWHML--------------------VNLCFHIFLTCVVFVGGITQ--
---TRNASICQAVGIILHYSTLATVLWVGVTAR----------------------------------NIYKQVTKKAKRC
QDPDE-------PPPPPRPMLRFYLIG-GGIPIIVCGITAAA-------NIKNYGSRP--NAPYCWMAWEPSLG------
-----------AFYGPASFITFVNCMYFLSI-------------------------------------------------
------------------FIQLKRHPERKYELKE-------PTEEQQRLAANENGE----------------INHQDS--
----------MSLSLISTSALENEHTFHSQLLGASLTLLLYVALWMFGALAVSLYY-----PLDLVFSFVFG----ATSL
SFSAFFVVHHCVNREDVRLAWIMT----------CCPGRSSYS----VQVNVQPPN-----------SNGTNGEAPK---
--------------------------------------------------------CPNSSAESSCTNKSASSFKNSSQ-
GCKLTNLQAAAAQCHANS-------------------------------------LPLNSTPQLDNSLTEHSMDN-----
------------------DIKMHVAPLEVQFRT-------NVHSS-------RHHKNRSKGHRASRLTV-----------
-----------------LREYAYDVPT---SVEG-SVQ---NGLPK----------------------------------
------------------SRLGNNEGHSRSRR------AYLAYRERQYNPPQQ---------------------------
------------------------------------DSSDACST-LPKSSR--------------NFEKPVSTTSKKDAL
RKPAVVELENQQKSYGLNLAIQNG-PIKS----------NGQEGPLLGTDSTG---NVRTGLWKHETTV-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------
>Gorilla_gorilla_GPR125
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------MEPPGRRRGRAQPPLLLQLSLLALLALLGGGGGGGAAALPAGCKHDG---RPRGAGR-------AAG
AAEGKVVCSSLEL-------AQVLPPDTLPNRT--VTLILSNNKISELKNGSF---------------------------
---SGLSLLERLDLRNNLISSIDPGAFWGLSS---LKRL-DLTNNRIGCLNADVFRG-LTNLVRLNLSG-----------
------------------------------------NLFSSLSQGTFDYLA------------------------SLRSL
--------------------------------------------------------------------------------
--------------------------------------------------------EFQTEYLLCDCNILWMHRWVKE-K
NITVR-DTRCVYPKSLQAQPVTGVKQELLTCDPPLELPSFYMTPSHRQVVFEGDSLP---FQCMASYIDQ----------
---------DMQVLWYQDGR------------IVETDESQGIFVEKNMIHNCSLIASALTISNIQAGSTGNWGCHVQTKR
GNNTRTVDIVVLESS----------------------AQYCPPERVVNNKGD---FRWPRTLAGITAYLQCTRNTHGSGI
YPGNP-----------QDERKAWRRCD--RGGFWADDDYSRCQYANDVTRVLYMFNQMPLN-------------------
----LTNAVATARQLLAYTVEAANF---SDKMDVIFVAEMIEKFGRFTKEEKSK-ELGDVMVDIASNIMLADERVLWLAQ
REAKACSRIVQCLQRIATYRLAGGA--------HVYSTYSPNIALEAYVIKST---GFTGMTCTVFQKVAASDRTGLS-D
YGRR---DPEGNLDKQLSFKCNVSNTFSSLALKN---TIVEASIQLPPSLFSPKQ----KRELRPTDDSLYKLQLIAFRN
GKLFPATG---NSTNLADDGKRRTVVTPVILTKID-GVNVDTHHIPVNVT----------------LRRIAHG----ADA
VAARWDFDLLNGQGGWKSDGCHILYSDENITTIQCYSLSNYAVLMDLTGSELYTQ------------AASLLHP--VVYT
TAIILLLCLLAVIVSYIYH-----HSLIRISLKSWHML--------------------VNLCFHIFLTCVVFVGGITQ--
---TRNASVCQAVGIILHYSTLATVLWVGVTAR----------------------------------NIYKQVTKKAKRC
QDPDE-------PPPPPRPMLRFYLIG-GGIPIIVCGITAAA-------NIKNYGSRP--NAPYCWMAWEPSLG------
-----------AFYGPASFITFVNCMYFLSI-------------------------------------------------
------------------FIQLKRHPERKYELKE-------PTEEQQRLAANENGE----------------VNHQDS--
----------MSLSLISTSALENEHTFHSQLLGASLTLLLYVALWMFGALAVSLYY-----PLDLVFSFVFG----ATCL
SFSAFFMVHHCVNREDVRLAWIMT----------CCPGRSSYS----VQVNVQPPN-----------SNGTNGEAPK---
--------------------------------------------------------CPNSSAESSCTNKSASSFKNSSQ-
GCKLTNLQAAAAQCHANS-------------------------------------LPLNSTPQLDNSLTEHSMDN-----
------------------DIKMHVAPLEVQFRT-------NVHSS-------RHHKNRSKGHRASRLTV-----------
-----------------LREYAYDVPT---SVEG-SVQ---NGLPK----------------------------------
------------------SRLGNNEGHSRSRR------AYLAYRERQYNPPQQ---------------------------
------------------------------------DSSDACST-LPKSSR--------------NFEKPVSTSSKKDAL
RKPAVVELENQQKSYGLNLAIQNG-PIKS----------NGQEGPLLGTDSTG---NVRTGLWKHETTV-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------
>Macaca_mulatta_GPR125
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------MEPPGRRRGRAQPPLLLQLSLLALLALLGG--GGGAAALPAGCKHDG---RPRGSGR-------AAG
AAEGKVVCSSLEL-------AQVLPPDTLPNRT--VTLTLFTNKITLK--GQD---------------------------
---LDISLYETLDLRNNLISSIDPGAFWGLSS---LKRL-DLTNNRIGCLNADIFRG-LTNLVRLNLSG-----------
------------------------------------NLFSSLSQGTFDYLA------------------------SLRSL
--------------------------------------------------------------------------------
--------------------------------------------------------EFQTEYLLCDCNILWMHRWVKE-R
NITVR-DTRCVYPKSLQAQPVTGVKQELLTCDPPLELPSFYMTPSHRQVVFEGDSLP---FQCMASYIDQ----------
---------DMQVLWYQDGR------------IVETDESQGIFVEKNMIHNCSLIASALTISNIQAGSTGNWGCHVQTKR
GNNTRTVDIVVLESS----------------------AQYCPPERVVNNKGD---FRWPRTLAGITAYLQCTRNTHGSGI
YPGNP-----------QDERKAWRRCD--RGGFWADDDYSRCQYANDVTRVLYMFNQMPLN-------------------
----LTNAVATARQLLAYTVEAANF---SDKMDVIFVAEMIEKFGRFTKEEKSK-ELGDVMVDIASNIMLADERVLWLAQ
REAKACSRIVQCLQRIATYRLAGGA--------HVYSTYSPNIALEAYVIKAT---GFTGMTCTVFQKVAASDRTGLS-D
YGRR---DPDGNLDKQLSFKCNVSNTFSSLALKN---TIVEASIQLPPSLFSPKQ----KRELRPTDDSLYKLQLIAFRN
GKLFPATG---NSTNLADDGKRRTVVTPVILTKID-GVNVDTHHIPVNVT----------------LRRIAHG----ADA
VAARWDFDLLNGQGGWKSDGCHILYSDENITTIQCYSLSNYAVLMDLTGSELYTQ------------SASLLHP--VVYT
TAIILLLCLLAVIVSYIYH-----HSLIRISLKSWHML--------------------VNLCFHIFLTCVVFVGGITQ--
---TRNASVCQAVGIILHYSTLATVLWVGVTAR----------------------------------NIYKQVTKKAKRC
QDPDE-------PPPPPRPMLRFYLIG-GGIPIIVCGITAAA-------NIKNYGSRP--NAPYCWMAWEPSLG------
-----------AFYGPASFITFVNCMYFLSI-------------------------------------------------
------------------FIQLKRHPERKYELKE-------PTEEQQRLAANENGE----------------INHQDS--
----------MSLSLISTSALENEHTFHSQLLGASLTLLLYVALWMFGALAVSLYY-----PLDLVFSFVFG----ATCL
SFSAFFMVHHCVNREDVRLAWIMT----------CCPGRSSYS----VQVNVQPPN-----------SSGTNGEASK---
--------------------------------------------------------CANSSAESSCTNKSASSFKNSSQ-
GCKLTNLQAAAAQCHANS-------------------------------------LPLNSTPQLDNSLTEHSMDN-----
------------------DIKMHVAPLEVQFRT-------NVHSS-------RHHKNRSKGHRASRLTV-----------
-----------------LREYAYDVPT---SVEG-SVQ---NGLPK----------------------------------
------------------SRLGNHEGHSRSRR------AYLAYRERQYNRPQQ---------------------------
------------------------------------DSSDACST-LPKSSR--------------NFEKPVSTSSKKDAL
RKPAVVELENQQKSYGLNLAIQNG-PIKS----------TGQEGSLLGTDSTG---NVRTGLWKHETTV-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------
>Mus_musculus_GPR125
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------MEPPPPLLLLPLALLALLWGGERG-AAALPAGCKHDG---RARGTGR-------AAA
AAEGKVVCSSLEL-------AQVLPPDTLPNRT--VTLILSNNKISELKNGSF---------------------------
---SGLSLLERLDLRNNLISRIAPGAFWGLSS---LKRL-DLTNNRIGCLNADVFRG-LTNLVRLNLSG-----------
------------------------------------NLFTSLSQGTFDYLG------------------------SLRSL
--------------------------------------------------------------------------------
--------------------------------------------------------EFQTEYLLCDCNILWMHRWVKE-R
NITVR-DTRCVYPKSLQAQPVTGVKQELLTCDPPLELPSFYMTPSHRQVVFEGDSLP---FQCMASYIDQ----------
---------DMQVLWYQDGR------------IVETDESQGIFVEKSMIHNCSLIASALTISNIQAGSTGNWGCHVQTKR
GNNTRTVDIVVLESS----------------------AQYCPPERVVNNKGD---FRWPRTLAGITAYLQCTRNTHSSGI
YPGSA-----------QDERKAWRRCD--RGGFWADDDYSRCQYANDVTRVLYMFNQMPLN-------------------
----LTNAVATARQLLAYTVEAANF---SDKMDVIFVAEMIEKFGRFTREEKSK-ELGDVMVDVASNIMLADERVLWLAQ
REAKACSRIVQCLQRIATHRLASGA--------HVYSTYSPNIALEAYVIKAA---GFTGMTCSVFQKVAASDRAGLS-D
YGRR---DPDGNLDKQLSFKCNVSSTFSSLALKN---TIMEASIQLPSSLLSPKH----KREARAADDALYKLQLIAFRN
GKLFPATG---NSTKLADDGKRRTVVTPVILTKID-GATVDTHHIPVNVT----------------LRRIAHG----ADA
VAAQWDFDLLNGQGGWKSDGCCILYSDENITTIQCGSLGNYAVLMDLTGTELYTP------------AASLLHP--VVYT
TAITLLLCLLAVIISYMYH-----HSLIRISLKSWHML--------------------VNLCFHILLTCVVFVGGITQ--
---TRNASVCQAVGIILHYSTLATVLWVGVTAR----------------------------------NIYKQVTKKAKRC
QDPDE-------PPAPPRPMLRFYLIG-GGIPIIVCGITAAA-------NIKNYGSRP--SAPYCWMAWEPSLG------
-----------AFYGPASFITFVNCMYFLSI-------------------------------------------------
------------------FIQLKRHPERKYELKE-------PTEEQQRLAANENGE----------------INHQDS--
----------MSLSLISTSTLENEHSFQSQLLGASLTLLLYVILWMFGAMAVSLYY-----PLDLVFSFFFG----ATCL
SFSAFMMVHHCINREDVRLAWIMM----------CCPGRSSYS----VQVNVQPPN-----------SSATNGEAPK---
--------------------------------------------------------CTNSSAESSCTNKSASSFKNSSQ-
GCKLTNLQAAAAQYHSNA-------------------------------------LPVNATPQLDNSLTEHSMDN-----
------------------DIKMHVAPLDVQFRT-------NVHPS-------RHHKNRSKGHRASRLTV-----------
-----------------LREYAYDVPT---SVEG-SVQ---NGLPK----------------------------------
------------------SRPGSNEGHSRSRR------AYLAYRERQYNPPQQ---------------------------
------------------------------------DSSDACST-LPKSSR--------------NVEKPVSTSSKKDAP
RKPAAADLESQQKSYGLNLAVQNG-PVKS----------NGQEGPLLATDVTG---NVRTGLWKHETTV-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------
>Rattus_norvegicus_GPR125
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------MERPP--LLLPLALLALLWGGERG-AVALPAGCKHDG---RARGTGR-------AAG
-AEGKVVCSSLEL-------AQVLP-DTLPNRT--VTLILSNNKISELKNGSF---------------------------
---SGLSLLERLDLRNNLISRIAPGAFWGLSS---LKRL-DLTNNRIGCLNADVFRG-LTNLVRLNLSG-----------
------------------------------------NLFTSLSQGTFDYLG------------------------SLRSL
--------------------------------------------------------------------------------
--------------------------------------------------------EFQTEYLLCDCNILWMHRWVKE-R
NITVR-DTRCVYPKSLQAQPVTGVKQELLTCGPPLELPSFYMTPSHRQVVFEGDSLP---FQCMASYIDQ----------
---------DMQVLWYQDGR------------IVETDESQGIFVEKSMIHNCSLIASALTISNIQAGSTGNWGCHIQTKR
GNNTRTVDIVVLESS----------------------AQYCPPERVVNNKGD---FRFNKTLCVCVCVCVCVQGYSFSSF
KEGVK-----------HSQQNLTLEFE--R----LFDNWFRCGEWVNSVSINSPFGLMPLN-------------------
----LTNAVATARQLLAYTVEAANF---SDKMDVIFVAEMIEKFGRFTKEEKSK-ELGDVMVDVASNIMLADERVLWLAQ
REAKACSRIVQCLQRIATHRLASGA--------HVYSTYSPNIALEAYVIKAA---GFTGMTCSVFQKVAASDRTGLS-D
YGRR---DPDGNLDKQLSFKCNVSSTFSSLALKN---TIMEASIQLPSSLFSPKQ----KREVRATDDSLYKLQLIAFRN
GKLFPATG---NSTKLADDGKRRTVVTPVILTKID-GVTTDTHHVPVNVT----------------LRRIAHG----ADA
IAAQWDFDLLNGQGGWKSDGCCILYSDENITTIQCGSLGNYAVLMDLTGSELYTP------------AASLLHP--VVYT
TAITLLLCLLAVIISYMYH-----HSLIRISLKSWHML--------------------VNLCFHIFLTCVVFVGGITQ--
---TRNASVCQAVGIILHYSTLATVLWVGVTAR----------------------------------NIYKQVTKKAKRC
QDPDE-------PPAPPRPMLRFYLIG-GGIPIIVCGITAAA-------NIKNYGSRP--SAPYCWMAWEPSLG------
-----------AFYGPASFITFVNCMYFLSI-------------------------------------------------
------------------FIQLKRHPERKYELKE-------PAEEQQRLAANENGE----------------INPQDS--
----------MSLSLISTSTLENEHSFQSQLLGASLTLLLYITLWMFGAMAVSLDY-----PLDLVFSFFFG----ASCL
SFSAFIMVHHCINREDVRLSWIMM----------CCPGRGSYS----VQVNVQPPT-----------SSAANGEAPK---
--------------------------------------------------------CTNSSAESSCTNKSASSFKNSSQ-
GCKLTNLQAAAAQYHSNA-------------------------------------LPVSATPQLDNSLTEHSMDN-----
------------------DIKMHVAPLDVQFRA-------NMHPS-------RHHKNRSKGHRASRLTV-----------
-----------------LREYAYDVPT---SVEG-SGQ---SGSPK----------------------------------
------------------SRPGSSEGHSRSRR------AYLAYRERQCNPPQQ---------------------------
------------------------------------DSSDAGST-LPKSGR--------------NVEKPLSTSSKKDAP
RKPAAADLESQQKSYGLNLAVQNG-PVKS----------NGQEGPLLATDITG---NIRTGLWKHETTV-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------
>Felis_catus_GPR125
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------METASEEAEKPLQ--GFRILSNNKISELKNGSF---------------------------
---SGLSLLERLDLRNNLISSIDPGAFWGLSS---LKRL-DLTNNRIGCLNADIFRG-LTNLVRLNLSG-----------
------------------------------------NLFSSLSQGTFDYLG------------------------SLRSL
--------------------------------------------------------------------------------
--------------------------------------------------------EFQTEYLLCDCNILWMHRWVKE-R
NITVR-DTRCVYPKSLQAQPVTGVKQELLTCDPPLELPSFYMTPSHRQVVFEGDSLP---FQCMASYIDQ----------
---------DMQVLWYQDGR------------IVETDESQGIFVEKNMIHNCSLIASALTISNIQAGSTGNWGCHVQTKR
GNNTRTVDIVVLESS----------------------AQYCPPERVVNNKGD---FRWPRTLAGITAYLQCTRNIHGSGI
YPGNP-----------QDERKAWRRCD--RGGFWADDDYSRCQYANDVTRVLYMFNQMPLN-------------------
----LTNAVATARQLLAYTVEAANF---SDKMDVIFVAEMIEKFGRFTKEEKSK-ELGDVMVDIASNIMLADERVLWLAQ
REAKACSRIVQCLQRIATYRLANGA--------HVYSTYSPNIALEAYVIKAA---GFTGMTCTVFQKVAASDRTGLS-E
YGRR---DPDGNLDKQLSFKCNVSNTFSSLALKN---TIVEASIQLPPSLFSPKQ----KREVRPTDDSLYKLQLLAFRN
GKLFPATG---NSTNLADDGKRRTVVTPVILTKID-GVNVDTHHIPVNVT----------------LRRIAHG----ADA
VAAQWDFDLLNGQGGWKSDGCYILYSDENITTMQCNSLSNYAVLMDLTGSELYTQ------------AASLLHP--VVYT
TAVILLLSLLAVIVSYIYH-----RSLIRISLKGWHML--------------------VNLCFHIFLTCVVFVGGVTQ--
---TRNASICQAIGIILHYSTLATVLWVGVTAR----------------------------------NIYKQVTRKAKRC
QDPDE-------LPPPPRPMLRFYLIG-GGIPIIVCGITAAA-------NIKNYGSRP--HAPYCWMAWEPSLG------
-----------AFYGPASFITFVNCMYFLSI-------------------------------------------------
------------------FIQLKRHPERKYELKE-------PTEEQQRLAANENGE----------------VNHQDS--
----------LSLSLISTSALENEHTFHSQLLGASLTLLLYVALWMFGALAVSLYY-----PLDLVFSFFFG----ATCL
SLSAFIVVHHCVNREDVRLAWIMT----------CCPGRSSYS----VQVNVQPPS-----------SSGANGEAPK---
--------------------------------------------------------CTNSSAESSCTNKSTSSFKNSSQ-
GCKLTNLQAAAAQCHTNS-------------------------------------LPLNSTPQLDNSLTEHSMDN-----
------------------DIKMHVAPLEVQCRT-------NVHPS-------RHHKNRSKGHRASRLTV-----------
-----------------LREYAYDVPT---SVEG-SVQ---NGLPK----------------------------------
------------------SRPGNNEGHSRSRR------AYLAYRERQYNPPQP---------------------------
------------------------------------DSSDGCST-LPKSGR--------------NFEKPISNSSKKDAL
RKPIVVELESQQKSYGLNLAIQNG-PIKS----------SGQEGPLLGTDSTG---NVRTGLWKHETTV-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------
>Bos_taurus_GPR125
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------ILSNNKISELKNGSF---------------------------
---SGLSLLERLDLRNNLISSIDPGAFWGLSS---LKRL-DLTNNRIGCLNADIFRG-LTNLVRLNLSG-----------
------------------------------------NLFSSLSQGTFDYLG------------------------SLRSL
--------------------------------------------------------------------------------
--------------------------------------------------------EFQTEYLLCDCNILWMHRWVKE-R
NITVR-DTRCVYPKSLQAQPVTGVKQELLTCDPPLELPSFYMTPSHRQVVFEGDSLP---FQCMASYIDQ----------
---------DMQVLWYQDGR------------IVETDESQGIFVEKNMIHNCSLIASALTISNIQAGSTGNWGCHVQTKR
GNNTRTVDIVVLESS----------------------AQYCPPERVVNNKGD---FRWPRTLAGITAYLQCTRNAHGSGI
YPGNA-----------QDERKAWRRCD--RGGFWADDDYSRCQYANDVTRVLYMFNQMPLN-------------------
----LTNAVATARQLLAYTVEAANF---SDKMDVIFVAEMIEKFGRFTKEEKSK-ELGDVMVDIASNIMLADERVLGLAQ
REAKACSRIVQCLQRIATYRLANGA--------HVYSTYSPNIALEAYVIKAT---GFTGMTCTVFQKVAATDRTGLS-D
YGRR---DLDGNLDKQLSFKCNVSNTFSSLALKN---TIVEASIQLPPSLFSPKQ----KREVRPSDDSLYKLQLIAFRN
GKLFPATG---NSTNLADDGKRRTVVTPVILTKID-GVNIDTHHIPVNVT----------------LRRIAHG----ADA
VAAQWDFDLLNGQGGWKSDGCHILYSDENITTIQCYSLSNYAVLMDLTGSEFYTQ------------AAHLLHP--VVYT
TAVILLLCLLAVIVSYIYH-----HSLIRISLKGWHML--------------------VNLCFHIFLTCVVFVGGISQ--
---TRNASVCQAVGIILHYSTLATVLWVGVTAR----------------------------------NIYKQVTKKAKRC
QDPDE-------LPPPPRPMLRFYLIG-GGIPVIVCGITAAA-------NIKNYGSRP--NAPYCWMAWEPSLG------
-----------AFYGPASFITFVNCMYFLSI-------------------------------------------------
------------------FIQLKRHPERKYELKE-------PTEEQQRLAANENGE----------------VNHQDS--
----------MSQSLISTSALGNEHTFHAQLLGASLTLLLYVGLWMFGALAVSLYY-----PLDLVFSFFFG----ATCL
SLSAFIVVHHCVNREDVRLAWIMT----------CCPGRSTYS----VQVNVQPPS-----------SSGPSGEAPK---
--------------------------------------------------------CTNSSAESSCTNKSASSFKNSSQ-
GCKLTNLQAAAAQCHTNS-------------------------------------LPLNATPQLDNSLTEHSMDN-----
------------------DIKMHVAPLEVPFRT-------NMHPS-------RHHKNRSKGHRASRLTV-----------
-----------------LREYAYDVPT---SVEG-SVQ---NGLPK----------------------------------
------------------SRLGSNEGHSRSRR------AYLAYRERQYNPPQQ---------------------------
------------------------------------DSSDACST-LPKSSR--------------NFEKPVSTSSKKDAV
RKPTVVELESQQKSYGLNLAIQNG-PIKS----------SGQEGPLLGTDSTG---NVRTGLWKHETTV-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------
>Equus_caballus_GPR125
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------ILSNNKISELKNGSF---------------------------
---SGLSLLERLDLRNNLISSIDPGAFWGLSS---LKRL-DLTNNRIGCLNADVFRG-LTNLVRLNLSG-----------
------------------------------------NLFSSLSQGTFDYLG------------------------SLRSL
--------------------------------------------------------------------------------
--------------------------------------------------------EFQTEYLLCDCNILWMHRWVKE-R
NITVR-DTRCVYPKSLQAQPVTGVKQELLTCDPPLELPSFYMTPSHRQVVFEGDSLP---FQCMASYIDQ----------
---------DMQVLWYQDGR------------IVETDESQGIFVEKSMIHNCSLIASALTISNIQAGSTGNWGCHVQTKR
GNNTRTVDIVVLESS----------------------AQYCPPERVVNNKGD---FRWPRTLAGITAYLQCTRNTHGAGI
YPGNP-----------QDERKAWRRCD--RGGFWADDDYSRCQYANDVTRVLYMFNQMPLN-------------------
----LTNAVATARQLLAYTVEAANF---SDKMDVIFVAEMIEKFGRFTKEEKSK-ELGDVMVDIASNIMLADERVLWLAQ
REAKACSRIVQCLQRIATYRLANGA--------HVYSTVRLPSCQYPLSVLAN---TLFCALKDVLREYLIACRISVS-K
ED-W---DAPQNLVNLLTFSCNVSNTFSSLAAKEN--TIVEASIQLPPSLFSSKQ----KREVRPTDDSLYKLQLIAFRN
GKLFPATG---NSTNLADDGKRRTVVTPVILTKID-GVNVDTHHIPVNVT----------------LRRIAHG----ADA
VAAQWDFDLLNGQGGWKSDGCHILYSDENITTIQCYSLSNYAVLMDLTGSELYTQ------------AASLLHP--VVYT
TSIILLLCLLAVIVSYIYH-----HSLIRISLKGWHML--------------------VNLCFHIFLTCVVFVGGITQ--
---TRNASVCQAVGIILHYSTLATVLWVGVTAR----------------------------------NIYKQVTKKTKRC
QDPDE-------LPPPPRPMLRFYLIG-GGIPIIVCGITAAA-------NIKNYGSRP--NAPYCWMAWEPSLG------
-----------AFYGPASFITFVNCMYFLSI-------------------------------------------------
------------------FIQLRRHPERKYELKE-------PTEEQQRLAANEHGE----------------VNHQDS--
----------MSLSLISTSALENEHTFHSQLMGASLTLLLYVTLWMFGALAVSLYY-----PLDLVFSFFFG----ATCL
SLSAFIMVHHCVNREDVRLAWIMT----------CCPGRSSYS----VQVNVQPPN-----------SSGTNGEAAK---
--------------------------------------------------------CTNSSAESSCTNKSASSFKNSSQ-
GCKLTNLQAAAAQCHTNS-------------------------------------LPLNATPQLDNSLTEHSMDN-----
------------------DIKMHVAPLEVQFRT-------NVHPS-------RHHKNRSKGHRASRLTV-----------
-----------------LREYAYDVPT---SVEG-SVQ---NGLPK----------------------------------
------------------SRPGNTEGHSRSRR------AYLAYRERQYNPPQQ---------------------------
------------------------------------DSSDACST-LPKSSR--------------NFEKPVSTSSKKDTL
RKPIVVELESQQKSYGLNLAIQNG-PIKS----------NGQDGPLLGTDSTG---NVRTGLWKHETTV-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------
>Loxodonta_africana_GPR125
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------ALFALLGGSGCAAALPPGCKQDG---RPRGTGR-------AAG
AAEGKVVCSSLEL-------AQVLPPDTLPNRT--VTLILSNNKISELKNGSF---------------------------
---SGLSLLERLDLRNNLISSIDPGAFWGLSS---LKRL-DLTNNRIGCLNADIFRG-LTNLVRLNLSG-----------
------------------------------------NLFSSLSQGTFDYLG------------------------SLRSL
--------------------------------------------------------------------------------
--------------------------------------------------------EFQTEYLLCDCNILWMHRWVKE-R
NITVR-DTRCAYPKSLQAQPVTGVKQELLTCDAPLELPSFYMTPSHRQVVFEGDSLP---FQCMASYIDQ----------
---------DMQVLWSQDGR------------IVETDESQGIFVEKNMIHNCSLIASALTISNIQAGSTGNWGCHVQTKR
GNNTRTVDIVVLESS----------------------AQYCPPERVVNNKGD---FRWPRTLAGITAYLQCTRNTHGSGI
YPGSP-----------QDERKAWRRCD--RGGFWADDDYSRCQYANDVTRVLYMFNQMPLN-------------------
----LTNAVATARQLLAYTVEAANF---SDKMDVIFVAEMIEKFGRFTKEEKSK-ELGDVMVDIASNIMLADERVLWLAQ
REAKACSRIVQCLQRIATYRLANGA--------HVYSTSSPNIALEAYVIKAA---GFTGMTCTVFQKVATSDRTGLS-D
YGRR---DLDGNLDKQLSFKCNISNTFSSLALKN---TIVEATIQLPSSLFSPKQ----KREVRPTDDSLYRLQLIAFRN
GKLFPATG---NSTNLADDGKRRTVVTPVILTKID-GVNVDTHPIPVNVT----------------LRRIAHG----ADA
VAAQWDFDLLNGQGGWKSDGCHILYSDENITTIQCHSLSNYAVLMDLTGSELYTQ------------AADLLHP--VIYT
TAIILLLCLLAVIVSYIYH-----HSLIRISLKSWHML--------------------VNLCFHVFLTCVVFVGGVTQ--
---TRNVSICQAVGIILHYSTLATVLWVGVTAR----------------------------------NIYKQVTKKAKRC
QDPDE-------PPPPPRPMLRFYLIG-GGIPIIVCGITAAA-------NIKNYGSRP--NAPYCWMAWEPSLG------
-----------AFYGPASFITFVNCMYFLSI-------------------------------------------------
------------------FIQLKRHPERKYELKE-------PTEEQQRLAANENGE----------------VTHQDS--
----------MSLSLISTSVLENEHTFHSQLLGASLTLLLYVALWMFGALAVSLYY-----PLDLVFSFFFG----ATCL
SFSAFIMVHHCVNREDVRLAWIMT----------CCPGRSSYS----VQVNVQPPS-----------SSGTNGEAPK---
--------------------------------------------------------CTNSSAESSCTNKSASSFKNSSQ-
GCKLTNLQAAAAQCHTTS-------------------------------------LPLNSVPQLDNSLTEHSMDN-----
------------------DIKMHVAPLEVQFRT-------NMHPG-------RHHKNRSKGHRASRLTV-----------
-----------------LREYAYDVPT---SVEG-SVQ---NGLPK----------------------------------
------------------SRPGNNEGHSRSRR------AYLAYRERQYNPPQQ---------------------------
------------------------------------DSSDACST-LPKSSR--------------NFEKPVSTSSKKDAS
RKPIVVELESQQKSYGLNLAIQNG-PIKS----------NGQDGPLLSTDSTG---NVRTGLWRHETTV-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------
>Dasypus_novemcinctus_GPR125
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------------------------------------------------MHRWVKE-R
NITVR-DTRCAYPKSLQAQPVTGVRQELLTCDPPLELPSFYMTPSHRQVVFEGDSLP---FQCMASYIDQ----------
---------DMQVLWYQDGR------------IVETDEAQGIFVEKNMIHNCSLIASALTISNIQAGSTGNWGCHVQTKR
GNNTRTVDIVVLESS----------------------AQYCPPERVVNNKGD---FRWPRTLAGITAYLQCTRSNHGSGI
YPGNP-----------QDERKAWRRCD--RGGFWADDDYSRCQYANDVTRVLYMFNQMPLN-------------------
----LTNAVATARQLLAYTVEAANF---SDKMDVIFVAEMIEKFGRFTKEEKSK-ELGDVMVDIASNIMLADERVLWLAQ
KEAKACSRIVQCLQRIATYRLANGA--------HVYSTYSPNIALEAYVIKAT---GFTGMTCTVFQKVAASDRTGLS-D
YGRR---DPDGNLDKQLSFKCNVSNTFSSLALKN---TIIEASIQLPPSLFSPKQ----KREVRPTDDSLYKLQLIAFRN
GKLFPATG---NSTNLADDGKRRTVVTPVILTKID-GVNADTHPIPVNVT----------------LRRIAHG----ADA
VAAQWDFDLLNGQGGWKSDGCHILYSDENITTIQCYSLSNYAVLMDLTGSELYTQ------------AAVLLHP--VVYT
TAVILLLCLLAVIVSYIYH-----HSLIRISLKSWHML--------------------VNLCFHIFLTCVVFVGGITQ--
---TRNASVCQAVGIILHYSTLATVLWVGVTAR----------------------------------NIYKQVTKKAKSC
QDPDE-------PPPPPRPMLRFYLIG-GGIPIIVCGITAAA-------NIKNYGSRP--HAPYCWMAWEPSLG------
-----------AFYGPASFITFVNCMYFLSI-------------------------------------------------
------------------FIQLKRHPERKYELKE-------PTEEQQRLAVNENGE----------------INHQDS--
----------MSLSLISTSALENEHTFHSQLLGASLTLLLYVALWMFGALAVSLYY-----PLDLVFSFFFG----ATCL
SFSAFLMVHHCINREDVRLAWIMT----------CCPGRSSYS----VQVNIQPPS-----------SSGTNGEPPK---
--------------------------------------------------------CTNSSAESSCTNKSASSFKNSSQ-
GCKLTNLQAAAAQCHASS-------------------------------------LPLNSMPQLDNSLTEHSMDN-----
------------------DIKMHVAPLEVQFRT-------NVHPS-------RHHKNRSKGHRASRLTV-----------
-----------------LREYAYDVPT---SVEG-SVQ---NGLPK----------------------------------
------------------SRPGSNEGHSRSRK------AYLAYRERQYNPPQQ---------------------------
------------------------------------DSSDACST-LPKSSR--------------NFEKPVSTSSKKDAL
RKPIAAELESQQKSYGLNLAIQNG-PIKS----------NGQDGPLLGTDSTG---NVRTGLWKHETTV-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------
>Gallus_gallus_GPR125
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------MLPPLRRAPCRPLRPRARRPARLLAALLLLAALRGGGTALPPGCKYDG---RPKSSGK-----AAAGG
PLEVKVVCSNLEL-------AHVLPPEALPNRT--VTLILSNNRITELKNCSF---------------------------
---SGLNLLERLDLKNNLISTIDPGAFLGLSS---LKRL-DLTNNRIGCLNADVFKG-LVNLIRLNLSG-----------
------------------------------------NLFSTLTQGTFDHLG------------------------SLKSL
--------------------------------------------------------------------------------
--------------------------------------------------------EFQTDYLLCDCNILWMHQWLKE-R
NITVR-ETKCAYPKSLQSQTVTGVKQELLTCEPPLELPSFYMTPSHRQVVFEGDSLP---FQCMASYIDQ----------
---------DMQVLWYQDGK------------IVETDESQGIFVEKNMIHNCSLIASALTISNIQAGSTGNWGCHVQTRR
GNNTRTVDIVVLESS----------------------AQYCPPERVVNNKGD---FRWPRTLAGITAYLLCTRYSAGSGI
YPGNS-----------QDERRAWRRCD--RGGYWAEEDYSRCQYANDVTRVLYMFNQMPLN-------------------
----LTNALATARQLLAYTVEAANF---SDKMDVIFVAEMIEKFGRFA--EKYK-ELGDVMVDIASNIMLADERVLWMAQ
RESKACTRIVQCLQKIAMYRLANGA--------QVYSTYSPNIALEAYVIKAA---GFTGMTCTVFQKVATSDRTGLS-D
YGRR---DPDGNLDKQLSFKCNVSNTLSSLALKN---TIIEASIQLPASLFTQKQ----KREIRPADESVYKLQLIAFRN
GKLFPATG---NSTNLADDGKRRTVVTPVILTKID-GLNPASHHVPINVT----------------LRRIAHG----ADA
VAAQWDFDLLNGQGGWKSDGCRILLSDENITTIQCYSLSNYAVLMDLTEAELYTQ------------PADLLHP--VIYA
TAMVLLMCLLMIIVSYIYH-----HSVIRISVKSWHML--------------------VNLSFHIFLTCVMFIGGITQ--
---TRNASICQAVGIILHYSTLATVLWLGVTSR----------------------------------NIYKQVTKKAKRC
QDTDE-------PPPPPRPMLRFYLIG-GGIPVIVCGITAAA-------NIRNYGSRP--NAPYCWMAWEPSLG------
-----------AFYGPASFIIFINCMYFLSI-------------------------------------------------
------------------FIQLKRHPERKYELKE-------PAEEQQRLATNEHGE----------------LTHQDS--
----------LSVSLVSTSALENEHSFQAQLMGVSLTLLLYIALWIFGALSVSLYY-----PMDLIFSCFFG----ATCL
SLSAFLMVHHCVNREDVRHAWITT----------CCPGRSTYS----VQVNVQPSS-----------SSGTNGETPK---
--------------------------------------------------------CTNSSAESSCTNKSAASLKNSSQ-
GCKLTNLQAAAAQCHSTS-------------------------------------LPLNTGPQLDNSLTEHSVDN-----
------------------DIKMHVAPLEVQFRT-------NGHPS-------RHHKNRSKGHRASRLAV-----------
-----------------LREYAYDVPT---SVEG-SVQ---NGVPK----------------------------------
------------------SRPSNSEGHSRSRR------AYLAYRERQYNQSQQ---------------------------
------------------------------------DSSDACST-LPKSSR--------------NTEKAIAANNKKEIL
RKPIVVELENQQKSYGLNLAIQNG-PLKS----------SGQDGPLLTADSTG---NIRTGLWKHETTV-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------
>Taeniopygia_guttata_GPR125
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------------------------------XPPGCKYDG---RPKSAGK-----AAAGG
PAEVKVVCSNLEL-------AQVLPPEALPNRT--VTLILSNNKITELKNGSF---------------------------
---SGLHLLERLDLKNNLISTIDPGAFLGLSS---LKRL-DLTNNRIGCLNADIFRG-LVNLIRLNLSG-----------
------------------------------------NLFSTLTQGTFDHLG------------------------SLKSL
--------------------------------------------------------------------------------
--------------------------------------------------------EFQTDYLLCDCNILWMHQWLKE-R
NITVR-ETKCAYPKSLQSQTVTGVKQELLTCEPPLELPSFYMTPSHRQVVFEGDSLP---FQCMASYIDQ----------
---------DMQVLWYQDGK------------IVETDESQGIFVEKNMIHNCSLIASALTISNIQAGSTGNWGCHVQTRR
GNNTRTVDIVVLESS----------------------AQYCPPERVVNNKGD---FRWPRTLAGITAYLLCTRYSAGSGI
YPGNS-----------QDERRAWRRCD--RGGYWADEDYSRCQYANDVTRVLYMFNQMPLN-------------------
----LTNAVATARQLLAYTVEAANF---SDKMDVIFVAEMIEKFGRFA--EKYK-ELGDVMVDIASNIMLADERVLWMAQ
REAKACTRIVQCLQKIAMYRLANGA--------QVYSTYSPNIALEAYVIKAA---GFTGMTCTVFQKVATSDRTGLS-D
YGRR---DPDGNLDKQLSFKCNVSNTLSSLALKN---TIVEASIQLPASLFTQKQ----KREIRPADESVYKLQLIAFRN
GKLFPATG---NSTNLADDGKRRTVVTPVILTKID-GLSIASHHVPINVT----------------LRRIAHG----ADA
VAAQWDFDLLNGQGGWKSDGCRILLSDENITTIQCYSLSNYAVLMDLTGAELYTQ------------PADLLHP--VIYA
TAMVLLMCLLMIMVSYIYH-----HSVIRISVKSWHML--------------------VNLSFHIFLTCIVFIGGITQ--
---TRNASICQAVGIILHYSTLATVLWLGVTSR----------------------------------NIYKQVTKKAKRC
QDPDE-------PPPPPRPMLRFYLIG-GGIPIIVCGITAAA-------NIRNYGSRP--NAPYCWMAWEPSLG------
-----------AFYGPASFIIFINCMYFLSI-------------------------------------------------
------------------FIQLKRHPERKYELKE-------PVEEQQRLATNEHGE----------------LAHQDS--
----------LSVSLVSTSALENEHSFPAQLLGVGLTLVLYVTLWIFGALSISLYY-----PMDLIFSCFFG----ATCL
SLSAFLMVHHCINREDVRHAWITT----------CCPGRSTYS----VQVNVPPSS-----------SSGTNGEAPK---
--------------------------------------------------------CTNSSAESSCTNKSASSLKNLSQ-
GCKLTNLQAAAAQCHPTS-------------------------------------LPLNTGPQLDNSLTEHSVDN-----
------------------DIKMHVAPLEVQFRT-------NGHPS-------RHHKNRSKGHRASRLAV-----------
-----------------LREYAYDVPT---SVEG-SVQ---NGLPK----------------------------------
------------------TRPSNSEGHSRSRR------AYLAYRERQYNQSQQ---------------------------
------------------------------------ESSDACST-LPKSSR--------------NTEKTIATSNKKDIL
KKPITAELENQQKSYGLNLAIQNG-PLKS----------SGQDGPLLTADSTG---NIRTGLWKHETTV-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------
>Anolis_carolinensis_GPR125
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------MAAPPSGRLLLLLFLALVEGGPGLPLGCKQDGPGGRPRSGKAGPL--SPSEA
GGGGKVVCTSLDL-------AHVLAPGALPNGT--VALILSNNKIAGLKNGSF---------------------------
---SGLSLLERLDLKNNLISVIDPGAFMGLTS---LKRL-DLANNQIGCLNVDMFKG-LANLVRLNLSG-----------
------------------------------------NLFSSLAQGTFDHLT------------------------SLKSL
--------------------------------------------------------------------------------
--------------------------------------------------------EFQTDYLLCDCNMLWMQQWVQE-R
NITVR-DTRCAYPKSLQAQPVLGVKQGLLTCGPPLELPSFYMTPSHRQVVFEGDSLP---FQCMASYIDQ----------
---------DMQVLWYQDGK------------IVETDESQGIFIEKSMIHNCSLIASALTISNIQAGSTGNWGCHVHTRR
GNNSRTVDIVVLNSS----------------------AQYCPPERVVNNKGD---FRWPRTLAGITAYLLCTRYSAGSGI
YPGNS-----------QDEKRAWRRCD--RGGFWAEEDYSRCQYANDATRVLYMFNQMPLN-------------------
----LTNAVATARQLLAYTVEAANF---SDKMDVIFVAEMIEKFGRFA--EKYK-ELGDVMVDIASNIILADEHILWMAQ
REAKACTRIVQCLQRIATYRLANGA--------QVYSTYSPNIAVEAYVIKSS---GFTGMTCTVFQKVAATDRIGLP-D
YGRR---DLDGGLDKQLGFKCNVSNTLSSLALKN---TIVEASIQLPPALFSKKH----KREIKPVDDTAYKLQLIAFRN
GKLFPTTG---NSTTLAAESKRLSVVTPVILTKID-GLNIPHPDIPINVT----------------LRRIANG----AHA
VAVQWDFDLLNGQGGWKSDGCHILSSDENVTTIQCYSLSNYAVLMDLSG---HIQ------------SLDSLHP--VIYV
SAVVLLICLLVIKVTYIYH-----HSVIKISLKSWHML--------------------VNLSFHIFLTCVMFIGGITQ--
---SKNASICQAVGIILHYSTLASLLWMGVTSR----------------------------------NIYKQVTKKSKRC
QDPDE-------PPPPPRPMLRFYLIG-GGIPIIVCGITAAA-------NIRNYGSRP--HSAYCWMTWEPSLG------
-----------AFYGPAGFIIFINCMYFLSI-------------------------------------------------
------------------FIQLKRHPERKFELKE-------PTEEQQRLASNEHGT----------------LNHQDS--
----------MSVSLVSTSALENEHSFHAQLLGVSLTLFLYVTLWILGAFSVSFSY-----PLDLVFSCFFA----AICL
SLSGFLLTQHCINREDVKHAWMTA----------CCPGRSTYS----VQVNIQPSSS----------ASGANGESAK---
--------------------------------------------------------CTNSSAESSCTSKSVASLKNSSQ-
ACKLTNIQAAAAQCPPAS-------------------------------------LAPNTGATLDNSLTEHSVDN-----
------------------EIKMHVAPLEVPLRT-------NGHPG-------RHHKNRSKGHRSSRLAV-----------
-----------------LREYAYDVPT---SVEG-SIQ---NGLTK----------------------------------
------------------SRQSVSEGHSRSRR------AYLAYRERQYTQSQQ---------------------------
------------------------------------DSSDACST-LHKGHW--------------NTEKSVPTNLKKDVL
RKPTVEDLEGQQKSYGLNLAVQNG-PLKN----------STQDGMLLSADSTG---NIRTGLWKHETTV-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------
>Pelodiscus_sinensis_GPR125
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------MPGPGRCPSPWPLLFLALLGGASLPPGCKLDG---RPKSPGR-----SPAEG
----KVVCSSLEL-------ARVLPPDALPNRT--VTLILSNNKILELKNGSF---------------------------
---SGLSLLERLDLKNNLISIINPGAFMGLPS---LKRL-DLSNNKIGCLNAEMFRG-LINLVRLNLSG-----------
------------------------------------NLFSSLTQGTLDHLN------------------------SLKSL
--------------------------------------------------------------------------------
--------------------------------------------------------EFQTDYLLCDCNILWMPQWLKE-R
NITVR-ETKCAYPKSLQSQLVTSVKQELLTCEPPLELPSFYMTPSHRQVVFEGDSLP---FQCMASYIDQ----------
---------DMQVLWYQDGK------------IVETDESQGIFVEKNIIHNCSLIASALTISNIQAGSTGNWGCHVQTRR
GNNTRTVDIVVLESS----------------------AQYCLPERVVNNKGD---FRWPRTLAGITAYLLCTRYSAGSGI
YPGNS-----------QDERRAWRRCD--RGGFWAEEDYSRCQYANDVTRVLYMFNQMPLN-------------------
----LTNAVATARQLLAYTVEAANF---SDKMDVIFVAEMIEKFGRFA--EKYK-ELGDVMVDIASNIMLADERVLWMSQ
REAKACTRIVQCLQRIAMYRLANGA--------QVYSTYSPNIALEAYVIKAA---GFTGMTCTVFQKVATSDRIGLS-D
YGRR---DPDGNLDKQLSFKCNVSNTLSSLALKN---TIVEASIQLPPSLFTQKQ----KREIRPANESIFKLQLIAFRN
GKLFPATG---NSTNLADNGKRRTVVTPVILTKID-GLSLASHHIAINVT----------------LRRIAHG----ADA
VAAQWDFDLLNGQGGWKSDGCHIISSDENITTIQCYSLSNYAVLMDLAGGELYTE------------PPVLLHP--VIYA
TSVVLLMCLLMIIVSYIYH-----HSVIRISVKSWHML--------------------VNLSFHIFLTCVMFIGGITQ--
---TKSTSVCQAVGIILHYSTLATVLWLGVTSR----------------------------------NIYKQVTKKAKRC
QDPDE-------PPPPPRPMLRFYLIG-GGIPIIVCGITAAA-------NIRNYGSRP--TTPFCWMTWEPSLG------
-----------AFYGPASFIIFINCMYFLSI-------------------------------------------------
------------------FIQLKRHPERKFELKE-------QAEEQQRLATNEHGE----------------LNHQDS--
----------VSVSLVSTSALENEHSFQAQLLGASLTLFLYVTLWIFGALAVSLYY-----PMDLILSCFFG----ATCL
SLSAFLMMHHCVNREDVRHAWITA----------CCPGRSTYS----VQVNVQPSN-----------SSGTNGETPK---
--------------------------------------------------------CTNSSAESSCTNKSASSLKNSSQ-
SCKLTNIQAAAAQCHPTS-------------------------------------LPLNTGPQLDNSLTEHSVDN-----
------------------DIKMHVAPLEIQFRT-------NGHQS-------RPHKNRSKGHRASRLTV-----------
-----------------LREYAYDVPT---SVEG-SVQ---NGLSK----------------------------------
------------------SRQSNSEGYSRSRR------AYLAYRERQYSQSQQ---------------------------
------------------------------------DSSDACST-LPKSNK--------------NTEKSIAANNKKEVL
RKPIVVELESQQKSYGLNLAIQNG-QLKG----------SGQDGPLITADSTG---NIRTGLWKHETTV-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------
>Danio_rerio_GPR125_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------ILSNNKIQELLNGSF---------------------------
---VGLSSLERLDIKNNIITHIEPGAFYGLFS---LKRLKDLSKNLIGCLHVDVFKG-LTNLVKLNLSE-----------
------------------------------------NKFSSLSQGIFDSLG------------------------SLKIL
--------------------------------------------------------------------------------
--------------------------------------------------------EFDSPYLLCDCNLQWLVVWIKE-K
AIGVK-ETRCSFPRSLQGQLITTLRAETLTCDAPLELPSFQMTPSQHQIVFQGDSLP---FQCMASFVDE----------
---------DMQVLWYQDGK------------MVEPDATQGIYIEKSMVQNCSLIASALTISNIQPGFTGNWECRVRTSR
GNNTRTVHIVVLESS----------------------AKYCLPDRVSNNKGE---YSLALHYTLVAFYLHCNYLSNYWVI
CHFYP-----------EAFDRTLKYTTENRSTFSTGNTCSESAVIHRPSYYLVQFYLPPIF-------------------
----HDGRAIVFRNSAAMSLRSSNT---RTVISFYFFQNNCRQKTQFFSAPVAF-SLGDVMVDISSNLLLADERVLWMAQ
REARACSRMVESLQRIALLRVSNG----------ALAYSTVSIEKNPH-VRQT---LWN---------------------
----------------FCFKR------------T---VQAVRYFQLSPAFLN------------------INLNIITYRN
GKLFPPTG---NSSILSDGSKRRSVVTPVMITKIE-GFPLRDLLSPVNVT----------------LRRFLQG----SDA
VPAFWNFSLQGGQGGWQSDGCRILHQDDNFTTVSCHSLNSYAVLMDLNRTGYNVF------------IFRPLHP--VIYS
TALVLVLCLLSVIVSYIYH-----HKSVRISKKCWHML--------------------VNLCLHILLTCAVFVGGINQ--
---TYNASVCQAMGIVLHYSTLATALWSGVTAR----------------------------------NIYKQVTRKAKRY
EELDE-------PPPPPRPMLRFYLIG-GGIPIIVCGITAAA-------NIKNYGSQV--NAPYCWMAWEPSLG------
-----------AFYGPAAFIVFVDCMYFLSI-------------------------------------------------
------------------LIQLRRHPERRFELKE-------QSEEQQHLSVTEATEITP-------------VHLESS--
----------PTAQPVPMSALENEHTFVSQLMGVAGSLTLYAALWVFGALAISQEH-----PADLVFACLFG----ALAL
GLGAFLVAHHCVNRQDMRRHWSQA----------CCLIRRNYA----VQG-----SSGSVMT------SRGNGEATK---
--------------------------------------------------------CPASSAESSCTNKSAPSLRNSTQ-
GCKLTNLQVEAAQCKVVAP------------------------------------STANGTAVLDNSLTEHSVDN-----
------------------EIKMHVAPIEIQYRPSNAN--ITGHPG-------RHHKNRSRAHRASRLTV-----------
-----------------LREYSYDVPT---SVEG-SVQ----SVPN----------------------------------
------------------KRHHHESLHARNSRR----AAYLAYRERQQSQLQQ---------------------------
------------------------------------DSSDAASTSVPRRSR--------------HFSKADVTNQTKECP
KQTLTVELEVQPKSYGLNLACQNGSAKDS----------ER-----LNVESSG---NVKTGLWKHETTV-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------
>Takifugu_rubripes_GPR125_a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----KVVCSNMEL-------HQVLPADSFPNRT--VTLILNNNKIQELRNGSF---------------------------
---FGLSALEKLDLRSNLISSVEPGAFLGLAA---LKRL-DLSNNSIGCLNVDVFKG-LASLMRLNLSG-----------
------------------------------------NVFSTIAPGTFDSLV------------------------SLKSL
--------------------------------------------------------------------------------
--------------------------------------------------------EFQTAFLLCDCNLLWLLRWIKE-R
SVAVK-STKCSYPQSLQGQLFTS-RPELFTCDAPLELPSFQLTPSQRQVVFQGDSLP---FQCQASFVAE----------
---------DMQVLWFQNGR------------MVKADAAQGIFIEKRMVQNCSLIASALTISNIQPGFTGNWECLVRTSR
GNTTRTVHIVVLETS----------------------AKYCAPERVSNNRGE---FRWPRTLAGIRAYLPCNRLPSSGGL
YSSSS-----------GEEQRAWRYCD--SKGVWAEDDYSRCQFQKDVTRFLYVINQMPLN-------------------
----ESNVVAKARRLLVCTIDAANF---SDKVDIIFVAEMIEKIGKFVEEFKDR-QLGEVMLSMASNLMMADERVLWMAQ
REALACSRIIACLQKIAVYRLATAP---------AFSLTSPNIALEAHAVRAG---DWNGMTCMLFQRPIPERSA-----
-----------GQDRQLTFKCNMTGSFSSLLHKS---TIVEASLQLPQALLTQPA----VP--GQPEDVVFKLHLLGFRN
GKFFPSTG---NSSQLADGGKRRSVATPVIMAKLE-GMPMHVLRTPVNIT----------------LRRLAHG----SDA
VSATWNFSLVGGQGGWQSDGCRILGHYDNFTTISCSSLGNYGLLMDLSSMEFFSP------------SILPLHP--VIYA
TAVVLLLCLVTVMVTYVYH-----HRAVRVSRKFWHML--------------------LNLCFHICLTFGVFAGGINQ--
---TRLAGVCQAVGILLHYSTLATALWVGVTAR----------------------------------NIYKQVTRKAKRY
EELDE-------PPPPPRPMLRFYLIG-GGIPIIVCGITAAA-------NIKNYGSRP--NAPYCWMAWEPSIG------
-----------AFYVPVGFIIFIDCMYFLSI-------------------------------------------------
------------------LLQLRRHPERRYELKE-------STEEQHPLSPPHADVGGDGPG-NRHPLTLPLQPPEAS--
----------SAHHAVPLSALENEHTFPAQLMGAAGALGLYAALWVFAAMAVSQEH-----PFDLVFTCLFG----VAAL
ALAAFMVAHHCINRQDVKRLWSRA----------CCSGRRAYS----AQEDVLLPQAGGAAAAATG--DKADGESTK---
--------------------------------------------------------CGHSSADSSCVNKSAASARNSAH-
GSKLTNIHAEAAQCKATAG-----------------------------------AAAGNGAAVLDNSLTEHSLDN-----
------------------EIKMHVAPVEVQFRP-------AAAAG-------RHHKNRARAHRASRLTV-----------
-----------------LREYAYDVPT---SVDG-SVQ----SAPH----------------------------------
------------------RRHHYYDMAARNSRR----AAYMAYRERHQSQLQQ---------------------------
------------------------------------DSSDSAS--LPRRPRHK----------DTERGVASANSSGKDSA
KQPSGSELENETKTYGVNLVTQNGAATKE----------NGQLLPLISTENAA---VVKTGLWKHETTV-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------
>Gasterosteus_aculeatus_GPR125_b
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------FTPPPPPADLLLRLLATLLLACGSAGSSDCKSYDEPPKGGKGGKKSPST----------
--ERKVVCSNMEL-------HQVLPADSFPNRT--VTLILNNNKIQELRNGSF---------------------------
---IGLFTLEKLDLRSNLISHIEPGAFLGLRA---LKKL-DLSNNSIGCLNVDIFKG-LTNLIRLNLSG-----------
------------------------------------NMFSSLSQGILDSLV------------------------SLKSL
--------------------------------------------------------------------------------
--------------------------------------------------------EFQTPYLLCDCNLLWLLRWIKE-R
SITVK-NTKCSFPQSLQGQLITSIKPELFTCDAPLELPSFQLTPSQRQVVFQGDSLP---FQCQASFVAE----------
---------DMQVLWYQNGR------------MVKSDAAQGIFIEKRMVQNCSLIASALTISNIQPGFTGNWECRVRTSR
GNTTRTVHIVVLESS----------------------AEYCAPERVSNNKGE---FKWPRTLAGIRAYLPCNRLPSSAGT
YSGGA-----------GEEQRAGRLCD--RKGLWTEEDYSRCQYQKDVTRFLYVINQMPLN-------------------
----ESNVVARARRLLVYTIDAANF---SDKMDIIFVAEMIEKFGKFVEKFKD---LGEVMLSMASNLMLADERVLWMAQ
REAMACSRIIACLQKIAVYRLATVQ---------VFSLTSPNVALESHVVRAN---DWNGMTCMLFQRSSPER-------
-----------TQERQLAFKCNTTSSFSSILHKS---PIVEASLQLPQSLFTQAA----LP--GQAEDTVYKLHLLGLRN
GKFFPSTS---NSTQLADGGKRRSVAAPVIMARIE-GMSPRVLRSPVNVT----------------LRRLARG----SDA
VSARWNFSLVGGHGGWQSDGCSIVGHNDNFTTISCNSLGNYGLLMDLSSVEYLSP------------SIQPLHP--VIYA
TTIILLISLLTIIISYIYH-----HRSVRVSRKFWHML--------------------VNLCFHISLTCGVFVGGINQ--
---TRHASVCQAVGILLHYSTLATALWVGVTAR----------------------------------NIYKQVTRKAKRY
EELDE-------PPPPPRPMLRFYLIG-GGIPIIVCGITAAA-------NIKNYGSRT--NAPYCWMSWEPSIG------
-----------AFYGPVGFIVFVDCMYFLSI-------------------------------------------------
------------------LLQLRRHPERRYELKE-------PSEEQQHLAPANGEAGSEGPGGQCVPLTLQLQPQGASPC
SA--------SAAHPVPLSALENEHTFAAQLMGAAGALGLYAALWVFGAMAVSQDH-----PYDLAFTCLFG----VAAL
ALGAFMVAHHCVNRQDMRRYWSQA----------CCSGRRAYS----AQEDVLLPQPGVAMTSTAGSASKADGESVK---
--------------------------------------------------------CGHSSADSSYTNKSAPSVRNSAH-
GSKLTNLHAEAAQCKPAP-------------------------------------ATANGGAVLDNSLTEHSLDN-----
------------------EIKMHVAPVEVQLRPVSNII-NAAAAATTNGHTSRHHKNRARAHRASRLTV-----------
-----------------LREYAYDVPT---SVEG-SVQGSAQSAPH----------------------------------
------------------RRHHHYDIAARNSRR----AAYMAYRERHQSQQQQQ--------------------------
------------------------------------DSSDGAS--LPRRSR------------LTEKGGAGTAGDGPPAP
DEAAGASLP---KSYGLNLVTQTGGAVKE----------NGHAGPLISPESAA---SVKTGLWKHETTV-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------
>Ciona_intestinalis_GPR125
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------LAENQISYIGPSTFTNFRN----LKRLNLSHNNIGRLDRSMFLG-LTSLERLYLNN-----------
------------------------------------NIFPLIPGDTFTSLT------------------------SLKRL
--------------------------------------------------------------------------------
--------------------------------------------------------NVSSTHLVCNCMMKEFLVWSKMNR
TTKLKLNGACTVPLSMKGINLKRVKIKRLKCDVLSDLPYFDIRPAKQQVVFEGDSIS---LHCEGTDLFH----------
---------AKIN-WSLNGV------------RISNSSMQMFNQTFRRSYDTSVVSSRLTLPNLTAQYSGVWGCTISSNI
SFVSKHTEIKVLKTT----------------------AKYCDRVNVTNDMGN---FTWHEAVTGVTVRYNCTEPQQEITM
EPHIAS-----------------RQCI--LPGVWSIGNYSQCQFHDPLARYSKVFNALYPL-------------------
---ITEKLVLYFKLLHCTSCNCSTK---MDYSKQISVALLAVSYVLCFVHIIS---LSSSILELMGKSMSSHAFYSILPS
HEVVQTCNKLQRILKTTAIGFLSNM--------TNINMKSSNIALAGYNFNVT---DQKYIYCSISEAIEWTELTKYP--
-------ELELVCQDLLLFNFSILLFFHSFLFFILHTYITITVTLG---------------VFVATTFKTIHLLHPGFKN
GNLFQSST---TTTNIKPDPERHVLVSSIYSVHVNNRNVVNLTKPAVYIFH--------------TQESVSQLNLDYEHY
IAMWNGSGWNRAHHHCIFNHTTRDQQQHNITVIQCDVLATFAIMKQIKVPSRGGNNG---------RQTTLTHP--TVYA
GSAVLTLTLLLMLITYAVFRKFIIFSSLLLSRDARHMI--------------------INTTLHLLVAVLTFTVGVWS--
---ISSKVMCYVTGILLHYSSLSVLLWITLSSG----------------------------------NICKEMLAAQQPP
LLEPK----------PSKPMLSLLFYY-GSIPIIICGITASA-------KIENYNGDG---GQYCWLSWETSLY------
-----------AFYAPAACIAIFCILVLLRI-------------------------------------------------
------------------LATLNCAPSGEVENEQ-------SSKTRLQGVALILVL---------------FITTWVT--
-----------AAMTVAAPRIQVCYSNFFNFWYLLLFYLFLISLKFFKQEEPTPSI-----DLHLIFSCIFA----MMCI
AMSSFLLIQHLTSRSDVRRSWRNL----------C---------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------
>Caenorhabditis_elegans_GPR125
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------MAKQLKYPFLIFIISLAQCQVSNQNVNLCQSNICQNGGTCLVASSVPATATCP
KNSIYYMGSCYVF-------DTTLRNWNDAALYCNNMNSATLPLVESAEDQAFF--------------------------
---AGYLQAMIPSNPPADMRPPPDGIWTAVRG-VNNVTRASWVYYPGSFLVTDTFWAPQEPNIYVNYNDVCVALQS----
-----------------------------------DSFYREWTTALCTILKYTVCKVAP-------------TQIQAKYV
AQCSCPN-------------------------------------------------------------------------
--------------------------------------------------------GYGGQTCETQSTTNQQASTQRTCG
SNDFQFSCPNDQTITVDFASFGAQESSMCNQASQSREQTCSNVNSLQTVINACQGLQSCEIRNLTSTFSNTPCPVP----
----QEQYLETRMRCETAQQPSCLSGLIQFDSRCYSMTIETNEKKQRTMEDAQTYCSQSGGSIITSPPDALLQQIVQKVN
AETKKTVNFWIGTPNNCQLLMVTG-----------SSTSYSQCPSSPSSTANVICSTVPQSTASVSARPTQSAPVDPVSQ
TMARREVYTGVQPPSVPDSINKPRYCKKEKKDGITYEQTRACMLHEQPCPDPQNVEGTVTRYCNCQTAKWETPDTTNCTH
RWVAEMETAIKDNQPVEDISSTVNRQLKSTIERTLFGGDITGTVRLSNDMLSLARNQFSVLNDRNLRENKARNFTENLGG
SGDQLLSPVAATVWDQLSSTIRIQHA-----SKLMSVLEQSVLLLGDYMTDQKLNLQYINWAMEVERSEPEVQTFGAAAS
PNVQDDMGMMRVMAAAPPAPQPETNTTIMFPSLKLSPTITLPSASLLSSLASPTPVAGGGPSILSSFQDDTPVGMASTPN
LNRNPVKLGYYAFAGFGQLLNNNNDHTLINSQVIGASIQNATQSVTLPVDHP-------------VTFTFQHLT---TKG
VSNPRCVYWDLMESKWSTLGCTLIATSSNSSQCSCTHLTSFAILMDISGQVGRLS------------GGLASALDVVSTI
GCAISIVCLALSVCVFTFFR--------NLQNVRNSIH--------------------RNLCLCLLIAELVFVIGMDR--
---TGNRTGCGVVAILLHYFFLSSFCWMLLEGY----------------------------------QLYMMLIQVFE--
--------------PNRTRIFLYYLFC-YGTPAVVVAISAGI-------KWEDYGTDS-----YCWIDTSTPTIW-----
-----------AFVAPIIVIIAANIIFLLIA-------------------------------------------------
------------------LKVVLSVQSRDRTKWG----------------------------------------------
-------------------------RIIGWLKGSATLLCLLGITWIFGFLTAVKGG------TGTAFAWIFT----ILNC
TQGIFIFVLHVVLNEKVRASIVRWLRTG----ICCLPETSSAAYNSRSFLSSRQRILN---------MIKVNGHSYP---
--------------------------------------------------------------STASTDDKEKQLTPITKT
TDWLSRLPNQDSVSIPES-----------------------------------------NFNNLNGTLENSNLNS-----
-------------------AEIKEEDEIPELRRR----------------------------------------------
-----------------------------VTVDLNPMIVSNNEIER----------------------------------
--------------------MSHASSDPRGSQ--------IIEVTAVEKKAP----------------------------
--------------------------------------------------------------------------------
---------VKRIKFPLGAKQSERGSQHR------------TKAKVIAPPESP---VSESGSKDYRF-------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------
>Homo_sapiens_GPR124
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------MGAGGRRMRGAPARLLLPLLP---WLLLLLAPEARGAPGCPLSIRSCKCSGERPKGLSGGVPGP
ARRRVVCSGGDLP-------EPP-EPGLLPNGT--VTLLLSNNKITGLRNGSF---------------------------
---LGLSLLEKLDLRNNIISTVQPGAFLGLGE----LKRLDLSNNRIGCLTSETFQG-LPRLLRLNISG-----------
------------------------------------NIFSSLQPGVFDELP------------------------ALKVV
--------------------------------------------------------------------------------
--------------------------------------------------------DLGTEFLTCDCHLRWLLPWAQN-R
SLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALELHTHHLIPSLRQVVFQGDRLP---FQCSASYLGN----------
---------DTRIRWYHNRA------------PVEGDEQAGILLAESLIHDCTFITSELTLSHIGVWASGEWECTVSMAQ
GNASKKVEIVVLETS----------------------ASYCPAERVANNRGD---FRWPRTLAGITAYQSCLQYPFTSVP
LGGGAPGTR------------ASRRCD--RAGRWEPGDYSHCLYTNDITRVLYTFVLMPIN-------------------
----ASNALTLAHQLRVYTAEAASF---SDMMDVVYVAQMIQKFLGYVDQIKE---LVEVMVDMASNLMLVDEHLLWLAQ
REDKACSRIVGALERIGGAALSPHA--------QHISVNARNVALEAYLIKPH---SYVGLTCTAFQRREGGVPGTRPGS
PGQNPPPEPEPPADQQLRFRCTTGRPNVSLSSFHIKNSVALASIQLPPSLFSSL-----PAALAPPVPPDCTLQLLVFRN
GRLFHSHS-NTSRPGAAGPGKRRGVATPVIFAGTS-GCGVGNLTEPVAVS----------------LRHWAEG----AEP
VAAWWSQEGPGEAGGWTSEGCQLRSSQPNVSALHCQHLGNVAVLMELSAFPREVG-----------GAGAGLHP--VVYP
CTALLLLCLFATIITYILN-----HSSIRVSRKGWHML--------------------LNLCFHIAMTSAVFAGGITL--
---TNYQMVCQAVGITLHYSSLSTLLWMGVKAR----------------------------------VLHKELTWRAPPP
QEGD-------PALPTPSPMLRFYLIA-GGIPLIICGITAAV-------NIHNYRDHS----PYCWLVWRPSLG------
-----------AFYIPVALILLITWIYFLCA-------------------------------------------------
------------------GLRLRGPLAQNPKAGNSRAS--LEAGEELRGSTRLRGS-------------GPLLSDSGSLL
ATGSA-----RVGTPGPPEDGDSLYSPGVQLGALVTTHFLYLAMWACGALAVSQRW-----LPRVVCSCLYG----VAAS
ALGLFVFTHHCARRRDVRASWRAC----------CPPASPAAPHAPPRALPAA----------AE-DGSPVFGEGPP---
S-------------------------------------------------------LK-----SSPSGSSGHPL---ALG
PCKLTNLQLAQSQVCEAGAAAGGEG--------------------------------EPEPAGTRGNLAHRHPNN-----
---------------------VHHGRRAHKSRAK-------GHRAGE-----ACGKNRLKALRGG---------------
--------------------AAGALELL--SSESGSLHNSPTDSYLG---------------------------------
---------------------SSRNSPGAGL-----------QLEGEPMLTPS---------------------------
------------------------------------EGSDTSAAPLSEA--------------GRAGQRRSASRDSLKGG
G---ALEKESHRRSYPLNAASLNGAP-----------KGGKYDDVTLMGAEVASGGCMKTGLWKSETTV-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------
>Gorilla_gorilla_GPR124
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------MRGAPARLLVPLLPLLPWLLLLLAPEARGAPGCPLPIRSCKCSGERPKGLSGGVPGP
ARRRVVCSGGDLP-------EPP-EPGLLPNGT--VTLLLSNNKITGLRNGSF---------------------------
---LGLSLLEKLDLRNNIISTVQPGAFLGLGE----LKRLDLSNNRIGCLTSETFQG-LPRLLRLNISG-----------
------------------------------------NIFSSLQPGVFDELP------------------------ALKVV
--------------------------------------------------------------------------------
--------------------------------------------------------DLGTEFLTCDCHLRWLLPWAQN-R
SLQLSERTLCAYPSALHAQALGSLQEAQLCCEGALELHTHHLIPSLRQVVFQGDRLP---FQCSASYLGN----------
---------DTRIRWYHNRA------------PVEGDEQAGILLAESLIHDCTFITSELTLSHIGVWASGEWECTVSMAQ
GNASKKVEIVVLETS----------------------ASYCPAERVANNRGD---FRWPRTLAGITAYQSCLQYPFTSVP
LGGGAPGTR------------ASRRCD--RAGRWEPGDYSHCLYTNDITRVLYTFVLMPIN-------------------
----ASNALTLAHQLRVYTAEAASF---SDMMDVVYVAQMIQKFLGYVDQIKE---LIEVMVDMASNLMLVDEHLLWLAQ
REDKACSRIVGALERIGGAALSPHA--------QHISVNARNVALEAYLIKPH---SYVGLTCTAFQRREGGVPGTRPGS
PGQNPLPEPEPPADQKLRFRCTTGRPNVSLSSFHIKNSVALASIQLPPSLFSSL-----PAALAPPVPPDCTLQLLVFRN
GRLFRSHS-NTSRPGAAGPGKRRGVATPVIFAGTS-GCGVGNLTEPVEEKN--------------NLGTLLLP----GHP
LPRGPRLTGPGKR----------KAGLGAWRGVHIPHVLLPALSQELSAFPREVG-----------GAGAGLHP--VVYP
CTALLLLCLFATIITYILN-----HSSIRVSQKGWHML--------------------LNLCFHMAMTSAVFAGGITL--
---TNYQMVCQAVGITLHYSSLSTLLWMGVKAR----------------------------------VLHKELTWRAPPP
QEGD-------PALPTPSPMLRFYLIA-GGIPLIICGITAAV-------NIHNYRDHS----PYCWLVWRPSLG------
-----------AFYIPVALSLLITWIYFLCA-------------------------------------------------
------------------GLRLRGPLAQNPKAG-----------EELRGSTRLRGS-------------GPLLSDSGSLL
ATGSA-----RVGTPGPPEDGDSLYSPGVQLGALVTTHFLYLAMWACGALAVSQRW-----LPRVVCSCLYG----VAAS
ALGLFVFTHHCX--------------------------------------------------------------------
--------------------------------------------------------------------------------
----------------------------------------------------------------------RHPNN-----
---------------------VHHGRRAHKSRAK-------GHRAGE-----ACGKNRLK--------------------
--------------------------LL--SSESGSLHNSPTDSYLG---------------------------------
---------------------SSRNSPGAGL-----------QLEGEPMLTPS---------------------------
------------------------------------EGSDTSAAPLSEV--------------GRAGQRRSASRDSLKGG
G---ALEKESHRRSYPLNAASLNGAP-----------KGGKYDDVTVMGAEVASGGCMKTGLWKSETTV-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------
>Macaca_mulatta_GPR124
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------MRGAPARLLLPLLL---WLLLLLAPEARGSPGCPLPIRSCKCSGERPKGLSGGVPGP
ARRRVVCGGGDLP-------EPP-EPGLLPNGT--VTLLLSNNKITGLRNGSF---------------------------
---LGLSLLEKLDLRNNIISTVQPGAFLGLGE----LKRLDLSNNRIGCLTSETFRG-LPRLLRLNISG-----------
------------------------------------NIFSSLQPGVFDELP------------------------ALKVV
--------------------------------------------------------------------------------
--------------------------------------------------------DLGTEFLTCDCRLRWLLPWAQN-R
SLQLSERTLCAYPSALHAQALGSLQEAQLCCEGALELHTHHLIPSLRQVVFQGDRLP---FQCSASYLGN----------
---------DTRIRWYHNRA------------PVEGDEQAGILLAESLIHDCTFITSGRTSAHCKLRLPGSRHSPASASR
VAGTTGARHLARLVF----------------------CLFCLVHRQLP-ASA---PRWPRTLAGITAYQSCLQYPFTSVP
LGGGAPGTR------------ASRRCD--RAGRWEPGDYSHCLYTNDITRVLYTFVLMPIN-------------------
----ASNALTLAHQLRVYTAEAASF---SDMMDVVYVAQMIQKFLGYVDQIKE---LVEVMVDMASNLMLVDEHLLWLAQ
REDKACSRIILDLVSIKNTKITQEC--------WHAPVNARNVALEAYLIKPH---SYVGLTCTAFQRREGGVPGAQPGS
PGQNPRPEPEPPADQQLRFRCTTGRPNVSLSSFHIKNSVALASIQLPPSLFSSL-----PAALAPPVPPDCTLQLLVFRN
GRLFRSHS-NASRPGAAGPGKRRGVATPVIFAGTS-GCGVGNLTEPVAVS----------------LRHWAEG----VEP
VAAWWSQEGPGGAGGWTSEGCQLRSSQPNVSALHCQHLGNVAVLMELSAFPREVG-----------GAGAGLHP--VVYP
CTALLLLCLFATIITYILN-----HSSIRVSRKGWHML--------------------LNLCFHMAMTSAVFAGGITL--
---TNYQMVCQAVGITLHYSSLSTLLWMGVKAR----------------------------------VFHKELTWRAPPP
QEGD-------PALPAPSPMLRFYLIA-GGIPLIICGITAAV-------NIHNYRDHS----PYCWLVWRPSLG------
-----------AFYIPVALILLITWIYFLCA-------------------------------------------------
------------------GLRLRGLLAQRPKGGNSRAS--LEAGEELRGSTRLRGS-------------GPLLSDSGSLL
ATGSA-----RVGTPGPPEDGDSLYSPGVQLGALVTTHFLYLAMWACGALAVSQRW-----LPRVVCSCLYG----AAAS
ALGLFVFTHHCARRRDVRASWRAC----------CPPASPSAPHALPRALPAA----------AAEDGSPVFGEGPP---
S-------------------------------------------------------LK-----SSPSGSSGHPL---ALG
PCKLTNLQLAQSQVCEAGAAACGEE--------------------------------EPEAAGPRGSLGPRHPNN-----
---------------------VHHGRRAHKGRAK-------GHRAGE-----AGGKNRLKALRGG---------------
--------------------AAGAPELL--SSESGSLHNSPTDSYLG---------------------------------
---------------------SSRNSPGVGL-----------QLEGEPMLTPS---------------------------
------------------------------------EGSDTSAAPLSEA--------------GRPGQRRSASRDSLKGG
G---ALEKESKRRSYPLNAASLNGVP-----------KGGKYDDVTMMGAEVASGGCMKTGLWKSETTV-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------
>Mus_musculus_GPR124
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------MGAGGRRMPVPPARLLLLPLLP---CLLL-LAPGTRGAPGCPVPIRGCKCSGERPKGLSGGAHNP
ARRRVVCGGGDLP-------EPP-DPGLLPNGT--ITLLLSNNKITGLRNGSF---------------------------
---LGLSLLEKLDLRSNVISTVQPGAFLGLGE----LKRLDLSNNRIGCLTSETFQG-LPRLLRLNISG-----------
------------------------------------NIYSSLQPGVFDELP------------------------ALKIV
--------------------------------------------------------------------------------
--------------------------------------------------------DFGTEFLTCDCRLRWLLPWARN-H
SLQLSERTLCAYPSALHAHALSSLQESQLRCEGALELHTHYLIPSLRQVVFQGDRLP---FQCSASYLGN----------
---------DTRIHWYHNGA------------PMESDEQAGIVLAENLIHDCTFITSELTLSHIGVWASGEWECSVSTVQ
GNTSKKVEIVVLETS----------------------ASYCPAERVTNNRGD---FRWPRTLAGITAYQSCLQYPFTSVP
LSGGAPGTR------------ASRRCD--RAGRWEPGDYSHCLYTNDITRVLYTFVLMPIN-------------------
----ASNALTLAHQLRVYTAEAASF---SDMMDVVYVAQMIQKFLGYVDQIKE---LVEVMVDMASNLMLVDEHLLWLAQ
REDKACSGIVGALERIGGAALSPHA--------QHISVNSRNVALEAYLIKPH---SYVGLTCTAFQRREVGVSGAQPSS
VGQDAPVEPEPLADQQLRFRCTTGRPNISLSSFHIKNSVALASIQLPPSLFSTL-----PAALAPPVPPDCTLQLLVFRN
GRLFRSHGNNTSRPGAAGPGKRRGVATPVIFAGTS-GCGVGNLTEPVAVS----------------LRHWAEG----ADP
MAAWWNQDGPGG---WSSEGCRLRYSQPNVSSLYCQHLGNVAVLMELNAFPREAG-----------GSGAGLHP--VVYP
CTALLLLCLFSTIITYILN-----HSSIHVSRKGWHML--------------------LNLCFHMAMTSAVFVGGVTL--
---TNYQMVCQAVGITLHYSSLSSLLWMGVKAR----------------------------------VLHKELSWRAPPL
EEGE-------AAPPGPRPMLRFYLIA-GGIPLIICGITAAV-------NIHNYRDHS----PYCWLVWRPSLG------
-----------AFYIPVALILPITWIYFLCA-------------------------------------------------
------------------GLHLRSHVAQNPKQGN-RIS--LEPGEELRGSTRLRSS-------------GVLLNDSGSLL
ATVSA-----GVGTPAPPEDGDGVYSPGVQLGALMTTHFLYLAMWACGALAVSQRW-----LPRVVCSCLYG----VAAS
ALGLFVFTHHCARRRDVRASWRAC----------CPPASPSASHVPARALPTA----------TE-DGSPVLGEGPA---
S-------------------------------------------------------LK-----SSPSGSSGRAP---PP-
PCKLTNLQVAQSQVCEASVAARGDG--------------------------------EPEPTGSRGSLAPRHHNN-----
---------------------LHHGRRVHKSRAK-------GHRAGE-----TGGKSRLKALRAG---------------
-------------------TSPGAPELL--SSESGSLHNSPSDSYPG---------------------------------
---------------------SSRNSPGDGL-----------PLEGEPMLTPS---------------------------
------------------------------------EGSDTSAAPIAET--------------GRPGQRRSASRDNLKGS
G--SALERESKRRSYPLNTTSLNGAP-----------KGGKYEDASVTGAEAIAGGSMKTGLWKSETTV-----------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------
>Rattus_norvegicus_GPR124
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------MGAGGRRMPVRSARLLLLPLLP---CLLL-LAPGTRGAPGCPVPIRGCKCSGERPKGLSGGAHNP
ARRRVVCGGGDLP-------EPP-DPGLLPNGT--ITLLLSNNKITGLRNGSF---------------------------
---LGLSLLEKLDLRSNVISTVQPGAFLGLGE----LKRLDLSNNRIGCLTSETFQG-LPRLLRLNISG-----------
------------------------------------NIYSSLQPGVFDELP------------------------DLKIV
--------------------------------------------------------------------------------
--------------------------------------------------------DFGTEFLTCDCRLRWLLPWARN-H
SLQLSERTLCAYPSALHAHALSSLQESQLRCEGALELHTHYLIPSLRQVVFQGDRLP---FQCSASYLGN----------
---------DTQIHWYHNGA------------PMESDEQAGIVLAENLIHDCTFITSELTLSHIGVWASGEWECSVSTVQ
GNTSKKVEIVVLETS----------------------ASYCPAERVTNNRGD---FRWPRTLAGITAYQSCLQYPFTSVP
LSGGAPGTR------------ASRRCD--RAGRWEPGDYSHCLYTNDITRVLYTFVLMPIN-------------------
----ASNALTLAHQLRVYTAEAASF---SDMMDVVYVAQMIQKFLGYVDQIKE---LVEVMVDMASNLMLVDEHLLWLAQ
REDKACSGIVGALERIGGAALSPHA--------QHISVNSRNVALEAYLIKPH---SYVGLTCTAFQRREVGVSGVQPSS
PGQDVPLEPEALADQQLRFRCTTGRPNVSLSSFHIKNSVALASIQLPPSLFSTL-----PAALAPPVPPDCTLQLLVFRN
GRLFRSHG-NTSRPGTAEPSKRRGVATPVIFAGTS-GCGVGNLTEPVAVS----------------LRHWAEG----TDP
LAAWWNQDGPGG---WSSEGCKLRFSQPNVSSLYCQHLGNVAVLMELSAFPREAG-----------GSGAGLHP--VVYP
CTALLLLCLFSTIITYILN-----HSSIHVSRKGWHML--------------------LNLCFHMAMTSAVFVGGVTL--
---TNYQMVCQAVGITLHYSSLSSLLWMGVKAR----------------------------------VLHKELSWRAPPP
EEGE-------AAPPGPRPMLRFYLIA-GGIPLIICGITAAV-------NIHNYRDHS----PYCWLVWRPSLG------
-----------AFYIPVALILPITWIYFLCA----