>Homo_sapiens_FGFR1
-----------------------------------------------MEARVSLKRRIELTVEYPWRCGALSPTSNCRTG
MWSWKCLLFWAVLVTATL---------------------CTARP------------------------------------
--------------SPTLPEQ------------------AQPWGAPVEVESFLVHPGDLLQLRCRLRDD---VQSINWLR
DGVQLAESN------RTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVS-----------------------
--------------------------------------------------------------------------------
--------------DALPSSEDDDDDDD-------SSSEEK--------------------------ETDNTKPN--PVA
PYWTS-----PEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEF-KPDHRIGGYKVRYAT--WSIIMDSVVPSD
KGNYTCIVENEYGSINHTYQLDVVER--SPHRPILQAGLPANKTVALGSNVEFMCK-VYSDPQPHIQWLKHIEVNGSKIG
P-DNLPYVQILKTAGVNTTDK---------------------------------EMEVLHLRNVSFEDAGEYTCLAGNSI
GLSHHSAWLTVL--------------------------------------------------------------------
------------------------------------EALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGT
-KKSD------FHSQMAVHKLAKSIPLRRQVT-----VSADSSASMNSGVLLVRP-SRLSSSGT------PMLAGVS--E
YELPEDPR--WELP-RD---RLVLGKPLGEG--CFGQVV-LAEAIGLDKDKPNRVT-KVAVKMLK---SDATEKDLSDLI
SEMEMMKMIGKHKNIINLLGACTQD---GPLYVIVEYASKGNLREYLQARRPPGLEY----------------CYNPSHN
PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGR---LPVKWM
APEALFDRIYTHQS----DVWSFGVLL----WEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWH
AVPSQRPTFKQLVEDLDRIVALTSNQ-----------------------------------------------EYLDLSM
P-LDQYSPSFPDTRSS-----------------TCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR-----------
------------------------------
>Pan_troglodytes_FGFR1
--------------------------------------------------------------------------------
MWSWKCLLFWAVLVTATL---------------------CTARP------------------------------------
--------------SPTLPEQ------------------AQPWGAPVEVESFLVHPGDLLQLRCRLRDD---VQSINWLR
DGVQLAESN------RTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVS-----------------------
--------------------------------------------------------------------------------
--------------DALPSSEDDDDDDDD------SSSEEK--------------------------ETDNTKPNRMPVA
PYWTS-----PEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEF-KPDHRIGGYKVRYAT--WSIIMDSVVPSD
KGNYTCIVENEYGSINHTYQLDVVER--SPHRPILQAGLPANKTVALGSNVEFMCK-VYSDPQPHIQWLKHIEVNGSKIG
P-DNLPYVQILKTAGVNTTDK---------------------------------EMEVLHLRNVSFEDAGEYTCLAGNSI
GLSHHSAWLTVL--------------------------------------------------------------------
------------------------------------EALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGT
-KKSD------FHSQMAVHKLAKSIPLRRQVT-----VSADSSASMNSGVLLVRP-SRLSSSGT------PMLAGVS--E
YELPEDPR--WELP-RD---RLVLGKPLGEG--CFGQVV-LAEAIGLDKDKPNRVT-KVAVKMLK---SDATEKDLSDLI
SEMEMMKMIGKHKNIINLLGACTQD---GPLYVIVEYASKGNLREYLQARRPPGLEY----------------CYNPSHN
PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGR---LPVKWM
APEALFDRIYTHQS----DVWSFGVLL----WEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWH
AVPSQRPTFKQLVEDLDRIVALTSNQ-----------------------------------------------EYLDLSM
P-LDQYSPSFPDTRSS-----------------TCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR-----------
------------------------------
>Macaca_mulatta_FGFR1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-----------------------------XPADSGLYACVTSSPLGSDTTYFSVNVS-----------------------
--------------------------------------------------------------------------------
--------------DALPSSEDDDDDDD-------SSSEEK--------------------------ETDNTKPNRMPVA
PYWTS-----PEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEF-KPDHRIGGYKVRYAT--WSIIMDSVVPSD
KGNYTCIVENEYGSINHTYQLDVVER--SPHRPILQAGLPANKTVALGSNVEFMCK-VYSDPQPHIQWLKHIEVNGSKIG
P-DNLPYVQILKTAGVNTTDK---------------------------------EMEVLHLRNVSFEDAGEYTCLAGNSI
GLSHHSAWLTVL--------------------------------------------------------------------
------------------------------------EALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGT
-KKSD------FHSQMAVHKLAKSIPLRRQTR-----VSADSSASMNSGVLLVRP-SRLSSSGT------PMLAGVS--E
YELPEDPR--WELP-RD---RLVLGKPLGEG--CFGQVV-LAEAIGLDKDKPNRVT-KVAVKMLK---SDATEKDLSDLI
SEMEMMKMIGKHKNIINLLGACTQD---GPLYVIVEYASKGNLREYLQARRPPGLEY----------------CYNPSHN
PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGR---LPVKWM
APEALFDRIYTHQS----DVWSFGVLL----WEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWH
AVPSQRPTFKQLVEDLDRIVALTSNQ-----------------------------------------------EYLDLSM
P-LDQYSPSFPDTRSS-----------------TCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR-----------
------------------------------
>Callithrix_jacchus_FGFR1
--------------------------------------------------------------------------------
MWSWKCLLFWAVLVTATL---------------------CTARP------------------------------------
--------------APTLPEQ------------------AQPWGAPVEVESFLVHPGDLLQLRCRLRDD---VQSIDWLR
DGVKLAESN------RTRITGEEVEVWDSVPADSGLYACVTSSPLGSDTTYFSVNVS-----------------------
--------------------------------------------------------------------------------
--------------DALPSSEDDDDDDD-------SSSEEK--------------------------ETDNTKPN--PVA
PYWTS-----PEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEF-KPDHRIGGYKVRYAT--WSIIMDSVVPSD
KGNYTCIVENEYGSINHTYQLDVVER--SPHRPILQAGLPANKTVALGSNVEFMCK-VYSDPQPHIQWLKHIEVNGSKIG
P-DNLPYVQILKTAGVNTTDK---------------------------------EMEVLHLRNVSFEDAGEYTCLAGNSI
GLSHHSAWLTVL--------------------------------------------------------------------
------------------------------------EALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIIYKMKSST
-KKSD------FHSQMAVHKLAKSIPLRRQVT-----VSADSSASMNSGVLLVRP-SRLSSSGT------PMLAGVS--E
YELPEDPR--WELP-RD---RLVLGKPLGEG--CFGQVV-LAEAIGLDKDKPSRVT-KVAVKMLK---SDATEKDLSDLI
SEMEMMKMIGKHKNIINLLGACTQD---GPLYVIVEYASKGNLREYLQARRPPGLEY----------------CYNPSHN
PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGR---LPVKWM
APEALFDRIYTHQS----DVWSFGVLL----WEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWH
AVPSQRPTFKQLVEDLDRIVALTSNQ-----------------------------------------------EYLDLSM
P-LDQYSPSFPDTRSS-----------------TCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR-----------
------------------------------
>Mus_musculus_FGFR1
--------------------------------------------------------------------------------
MWGWKCLLFWAVLVTATL---------------------CTARP------------------------------------
--------------APTLPEQ------------------AQPWGVPVEVESLLVHPGDLLQLRCRLRDD---VQSINWLR
DGVQLVESN------RTRITGEEVEVRDSIPADSGLYACVTSSPSGSDTTYFSVNVS-----------------------
--------------------------------------------------------------------------------
--------------DALPSSEDDDDDDD-------SSSEEK--------------------------ETDNTKPN--PVA
PYWTS-----PEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEF-KPDHRIGGYKVRYAT--WSIIMDSVVPSD
KGNYTCIVENEYGSINHTYQLDVVER--SPHRPILQAGLPANKTVALGSNVEFMCK-VYSDPQPHIQWLKHIEVNGSKIG
P-DNLPYVQILKTAGVNTTDK---------------------------------EMEVLHLRNVSFEDAGEYTCLAGNSI
GLSHHSAWLTVL--------------------------------------------------------------------
------------------------------------EALEERPAVMTSPLYLEIIIYCTGAFLISCMLGSVIIYKMKSGT
-KKSD------FHSQMAVHKLAKSIPLRRQVT-----VSADSSASMNSGVLLVRP-SRLSSSGT------PMLAGVS--E
YELPEDPR--WELP-RD---RLVLGKPLGEG--CFGQVV-LAEAIGLDKDKPNRVT-KVAVKMLK---SDATEKDLSDLI
SEMEMMKMIGKHKNIINLLGACTQD---GPLYVIVEYASKGNLREYLQARRPPGLEY----------------CYNPSHN
PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGR---LPVKWM
APEALFDRIYTHQS----DVWSFGVLL----WEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWH
AVPSQRPTFKQLVEDLDRIVALTSNQ-----------------------------------------------EYLDLSI
P-LDQYSPSFPDTRSS-----------------TCSSGEDSVFSHEPLPEEPCLPRHPTQLANSGLKRR-----------
------------------------------
>Oryctolagus_cuniculus_FGFR1
--------------------------------------------------------------------------------
MWSWKCLLFWAVLVTATL---------------------CTARPA-----------------------------------
--------------APTLPEQGKA------QAPVPGVAAAQPWGAPVEVESLLVHPGDLLQLRCRLRDD---VQSINWLR
DGVQLAESN------RTRITGEEVEVRDSVPADSGLYACVTSSPSGSDTTYFSVNVS-----------------------
--------------------------------------------------------------------------------
--------------DALPSSEDDDDDDD-------SSSEEK--------------------------ETDNTKPN--PVA
PYWTS-----PEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEF-KPDHRIGGYKVRYAT--WSIIMDSVVPSD
KGNYTCIVENEYGSINHTYQLDVVER--SPHRPILQAGLPANKTVALGSNVEFMCK-VYSDPQPHIQWLKHIEVNGSKIG
P-DNLPYVQILKTAGVNTTDK---------------------------------EMEVLHLRNVSFEDAGEYTCLAGNSI
GLSHHSAWLTVL--------------------------------------------------------------------
------------------------------------EALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIIYKMKSGT
-KKSD------FHSQMAVHKLAKSIPLRRQVT-----VSADSSASMNSGVLLVRP-SRLSSSGT------PMLAGVS--E
YELPEDPR--WELP-RD---RLVLGKPLGEG--CFGQVV-LAEAIGLDKDKPNRVT-KVAVKMLK---SDATEKDLSDLI
SEMEMMKMIGKHKNIINLLGACTQD---GPLYVIVEYASKGNLREYLQARRPPGLEY----------------CYNPSHN
PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGR---LPVKWM
APEALFDRIYTHQS----DVWSFGVLL----WEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWH
AVPSQRPTFKQLVEDLDRIVALTSNQ-----------------------------------------------EYLDLSM
P-LDQYSPSFPDTRSS-----------------TCSSGEDSVFSHEPLPEEPCLPRRSAQLANGGLKRR-----------
------------------------------
>Monodelphis_domestica_FGFR1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
---------------------------D-------SSSEEK--------------------------ESDNTKPN--PVA
PYWTS-----PEKMENKLHAVPAAKTVKFKCPSNGTPNPSLRCLKNGKEF-KPDHRIGGYKVRYAT--WSIIMDSVVPSD
KGNYTCIVEITFS--CFSFPFFSVER--SPHRPILQAGLPANKTVALGSNVEFMCK-VYSDPQPHIQWLKHIEVNGSKIG
P-DNLPYVQILKTAGVNTTDK---------------------------------EMEVLHLRNVSFEDAGEYTCLAGNSI
GLSHHSAWLTVL--------------------------------------------------------------------
------------------------------------EALEERPAVMTSPVYLEIIIYCTGAFLISCMVGSVIIYKMKSGT
-KKSD------FHSQMAVHKLAKSIPLRRQVTESRWGVSADSSASMNSGVLLVRP-SRLSSSGT------PMLAGVS--E
YELPEDPR--WELP-RD---RLVLGKPLGEG--CFGQVV-LAEAIGLDKDKPNRVT-KVAVKMLK---SDATEKDLSDLI
SEMEMMKMIGKHKNIINLLGACTQD---GPLYVIVEYASKGNLREYLQARRPPGLEY----------------CYNPSHA
PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGR---LPVKWM
APEALFDRIYTHQS----DVWSFGVLL----WEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWH
AIPSQRPTFKQLVEDLDRIVALTSNQ-----------------------------------------------EYLDLSV
P-LDQYSPSFPDTRSS-----------------TCSSGEDSVFSHDPLPEEPCLPRHPTQLANGGLKRR-----------
------------------------------
>Ornithorhynchus_anatinus_FGFR1
--------------------------------------------------------------------------------
MWSWKCLLFWAVLVTATL---------------------CPARA------------------------------------
--------------APTLPEH------------------ALPWGAPVEVESSLAHPGDLLQLRCRLRDD---VQSINWLR
DGVQLAESN------RTRITGEEVEVRDAVPSDSGLYACVT-TPSGSDITYFSVNVS-----------------------
--------------------------------------------------------------------------------
--------------DALPSAEDDDDDDD-------SSSEEK--------------------------ETDNTKPNRTPVA
PYWTS-----PEKMEKKLHAVPAAKTVKFKCPSSGTPSPTLRWLKNGKEF-KPDHRIGGYKVRYAT--WSIIMDSVVPSD
KGNYTCIVENKYGSINHTYQLDVVER--SPHRPILQAGLPANKTVALGSNVEFVCK-VYSDPQPHIQWLKHIEVNGSKIG
P-DNLPYVQILKTAGVNTTDK---------------------------------EMEVLHLRNVSFEDAGEYTCLAGNSI
GISHHSAWLTVL--------------------------------------------------------------------
------------------------------------EALEERPAVMTSPLYLEIIIYCTGAFLISCMVGTVIVYKMKSGT
-KKSD------FHSQMAVHKLAKSIPLRRQVT-----VSADSSTSMNSGVLLVRP-SRLSSSGT------PMLAGVS--E
YELPEDPR--WELP-RD---RLVLGKPLGEG--CFGQVV-LAEAIGLDKDKPNRVT-KVAVKMLK---SDATEKDLSDLI
SEMEMMKMIGKHKNIINLLGACTQD---GPLYVIVEYASKGNLREYLQARRPPGLEY----------------CYNPSHA
PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGR---LPVKWM
APEALFDRIYTHQS----DVWSFGVLL----WEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSNCTNDLYMMMRDCWH
AVPSQRPTFKQLVEDLDRIVALTSNQ-----------------------------------------------EYLDLSV
P-LDQYSPGFPDTRSS-----------------TCSSGEDSVFSHDPLPEEPCLPRHPAQLANGGLKRR-----------
------------------------------
>Gallus_gallus_FGFR1
--------------------------------------------------------------------------------
MFTWRCLILWAVLVTATL---------------------SAARP------------------------------------
--------------APTLPDQ------------------ALPK-ANIEVESHSAHPGDLLQLRCRLRDD---VQSINWVR
DGVQLPENN------RTRITGEEVEVRDAVPEDSGLYACMTNSPSGSETTYFSVNVS-----------------------
--------------------------------------------------------------------------------
--------------DALPSAEDDDDEDD-------SSSEEK--------------------------EADNTKPNQ-AVA
PYWTY-----PEKMEKKLHAVPAAKTVKFKCPSGGTPNPTLRWLKNGKEF-KPDHRIGGYKVRYAT--WSIIMDSVVPSD
KGNYTCIVENKYGSINHTYQLDVVER--SPHRPILQAGLPANKTVALGSNVEFVCK-VYSDPQPHIQWLKHIEVNGSKIG
P-DNLPYVQILKTAGVNTTDK---------------------------------EMEVLHLRNVSFEDAGEYTCLAGNSI
GISHHSAWLTVL--------------------------------------------------------------------
------------------------------------EATEQSPAMMTSPLYLEIIIYCTGAFLISCMVVTVIIYKMKSTT
-KKTD------FNSQLAVHKLAKSIPLRRQVT-----VSADSSSSMNSGVMLVRP-SRLSSSGT------PMLAGVS--E
YELPEDPR--WELP-PT---RLILGKPLGEG--CFGQVV-LAEAIGLDKDKPNRVT-KVAVKMLK---SDATEKDLSDLI
SEMEMMKMIGKHKNIINLLGACTQD---GPLYVIVEYASKGNLREYLQARRPPGMEY----------------CYNPTRI
PEEQLSFKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGR---LPVKWM
APEALFDRIYTHQS----DVWSFGVLL----WEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWH
AVPSQRPTFKQLVEDLDRIVAMTSNQ-----------------------------------------------EYLDLSV
P-LDQYSPGFPATRSS-----------------TCSSGEDSVFSHDPLPDEPCLPRCPP-HSHGALKRH-----------
------------------------------
>Taeniopygia_guttata_FGFR1
--------------------------------------------------------------------------------
MWTWRCLILWAVLVAAAL---------------------SAARP------------------------------------
--------------APTLPEQ------------------AVPK-AKIEVESHSAHPGELLQLRCRLRDD---VQSINWVH
DGVQLAENN------RTRITGEEVEVRDVVPEDSGLYACMTNSPSGSKTTYFSVNVS-----------------------
--------------------------------------------------------------------------------
--------------DALPSAEDDDDEDD-------SSSEEK--------------------------EADNTKPNQ-AIA
PYWTY-----PEKMEKKLHAVPAVKTVKFKCPSSGTSNPNL-WLKNGKEF-KPDHRIGGYKVQGGA--GEQLLG-VVPSD
KGNYTCMWRTSTAASTHTYQLDVVGRKRSPHRPILQAGLPANKTVALGSNVEFVCK-VYSDPQPHIQWLKHIEVNGSKIG
P-DNLPYVQILKTAGVNTTDK---------------------------------EMEVLHLRNVSFEDAGEYTCLAGNSI
GISHHSAWLTVL--------------------------------------------------------------------
------------------------------------EAIEDTPAMMTSPIYLEIIIYCIGAFLISCMVVTIIIYKLKSTT
-KKTD------FNSQLAVHKLAKSIPLRRQRS-----VSADSSSSMNSGVMLVRP-SRLSSSGT------PMLAGVS--E
YELPEDPR--WELP-RD---RLILGKPLGEG--CFGQVV-LAEAIGLDKDKPNRVT-KVAVKMLK---SDATEKDLSDLI
SEMEMMKMIGKHKNIINLLGACTQD---GPLYVIVEYASKGNLREYLQARRPPGMEY----------------CYNPSRV
PEEQLSFKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGR---LPVKWM
APEALFDRIYTHQS----DVWSFGVLL----WEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWH
AVPSQRPTFKQLVEDLDRIVAMTSNQV---------------------------------------------GEYLDLSM
P-LDQYSPGFPDTRSS-----------------TCSSGEDSVFSHDPLPDEPCLPKFPPQHSNGGLKRH-----------
------------------------------
>Anolis_carolinensis_FGFR1
--------------------------------------------------------------------------------
MPARRCLHAARVNASAIVHS-------------------CLAFPL-----------------------------------
--------------PPSLSLFSP-------------LTLPVLPKTSIEVESLSAHPGDPLQLRCRLRDD---VQSINWVR
DGVQLAENN------RTRITGEEVEVRDAVPEDSGLYACMTNSPSGSETTYFSVNVS-----------------------
--------------------------------------------------------------------------------
--------------DALPSAEDDDDDDD-------SSSEEK--------------------------EADNSKPNRMVTP
VWLCC-----PCRVQSRMRSTGADKTLG----------PTLRWRSK--ED-TVILSMHAFLVRHAT--WSIIMESVVPSD
KGNYTCIVENKYGTINHTYQLDVVER--SPHRPILQAGLPANKTVSLGSNVEFVCK-VYSDPQPHIQWLKHIEVNGSRIG
P-NNLPYVQVLKTAGVNTTDK---------------------------------EMEVLHLRNVSFEDAGQYTCLAGNSI
GISHHSAWLTVL--------------------------------------------------------------------
------------------------------------EAMEDKPAMMTSPLYLEIIIYCTGGFLISCMIVTVLLYKMKSTT
-KKTD------FNSQLAVHKLAKSIPLRRQVT-----VSADSSSSMNSGVMLMRP-SRLSSSGT------PMLAGVS--E
YDLPEDPR--WELP-RD---RLILGKPLGEG--CFGQVV-LAEAIGLDKDKPNRVT-KVAVKMLK---SDATEKDLSDLI
SEMEMMKMIGKHKNIINLLGACTQD---GPLYVIVEYASKGNLREYLQARRPPGMEY----------------CYNPTHL
PDEQLSFKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDSVMKIADFGLARDIHHIDYYKKTTNGR---LPVKWM
APEVLYKNLYRVHWA-CLHRWSFGVLL----WEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWH
AVPSQRPTFKQLVEDLDRIVAMTSNQ-----------------------------------------------EYLDLSM
P-LDQYSPSFPDTRSS-----------------TCSSGEDSVFSHDPLPDEPCLPKHPPQLANGGLKRR-----------
------------------------------
>Xenopus_tropicalis_FGFR1
--------------------------------------------------------------------------------
MFSGRSLLLWGVLLGAAL---------------------SVARP------------------------------------
--------------PSTLPDQ-------------------VAPKTKTDVEPYSARPGDRITLQCRLRED---VQSINWAK
NEMQLSETN------RTRITGEEIQISNAGPEDNGVYTCVTNGPSGTYTVLFSVNVS-----------------------
--------------------------------------------------------------------------------
--------------DALPSAEDDDDDDDN------SSSEEK--------------------------ASENSKPN----R
PFWSH-----PEKMEKKLHAVPAAKTVKFRCPANGTPQPNLRWLKNGKEF-RQDQRIGGYKVRSQT--WSLIMDSVVPSD
KGNYTCIVENKYGTLNHTYQLDVVER--SPHRPILQAGLPANTSVIVGSTAEFFCK-VYSDPQPHIQWLRHIEINGSRVA
S-DGFPYVEILKTAGVNTSDK---------------------------------DMEVLHLRNVTFEDAGQYTCLAANSI
GISHHSAWLTVL--------------------------------------------------------------------
------------------------------------EVEDDKPAPLASPLQLEIIIYCTGAAFVSAMVITIIIFKMKHPS
-KKSD------FNSQLAVHKLAKSIPLRRQVT-----VSGDSNSSMHSGVILVRP-SRLSSSGT------PMLSGVS--E
YELPEDPR--WEVA-RD---RLILGKPLGEG--CFGQVV-MAEAIGLDKEKPNKVT-KVAVKMLK---SDASEKDLSDLI
SEMEMMKMIGKHKNIINLLGACTQD---GPLYVIVEYASKGNLREYLRARRPPGMEY----------------CYNPTCA
PDQLLSFKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGR---LPVKWM
APEALFDRIYTHQS----DVWSFGVLL----WEIFTLGGSPYPGVP-MEELFKLLKEGHRMDKPTTCTNELYMMMKDCWH
AMPSQRPTFNQLVEDLDRILALSSNQ-----------------------------------------------EYLDLSM
P-VNQYSPCFPDTRSS-----------------TCSSGEDSVFSHDPLPDEPCLP----KYSNGGLKKR-----------
------------------------------
>Danio_rerio_FGFR1
----------------------------------------------------------------------------MKMM
MIMKTTLLLISVLLTQALQ--------------------SQGRP------------------------------------
---------------AIQDEA----------------------PAEP--TSYTLDSGEKLELSCKAKED---TQKVTWTK
DLVPLVDGE------HTRLRNDQMEIEKVEPTDSGLYACFAQGLNSNHTEYFNIS-------------------------
--------------------------------------------------------------------------------
-------------------VTDEEDEVD-------SSSEEA--------------------------KLSNDQN--LPMA
PVWAQ-----PDKMEKKLHAVPASKTVKFRCQANGNPTPTLKWLKNGKEF-KRDQRIGGFKVREHM--WTIIMESVVPSD
RGNYTCLVENRHGSINHTYQLDVVE--RSPHRPILQAGLPANRTAVVGSDVEFECK-VFSDPQPHIQWLKHIEVNGSRYG
P-DGLPYVRALKTAGVNTTDK---------------------------------EMEVLQIRNVSLEDAGEYTCLAGNSI
GHSHHSAWLTVY--------------------------------------------------------------------
------------------------------------KAVPPTQLPNQT--YLEVLIYCVGFFLICVMVGTAVLAKMHSSA
-KKSD------FNSQLAVHKLAKSIPLRRQVT-----VSVDSSSSMHSGGMLVRP-SRLSSSGS------PMLSGVS--E
YELPQDPR--WEVQ-RD---RLVLGKPLGEG--CFGQVM-MAEAMGMDKEKPNRIT-KVAVKMLK---SDATEKDLSDLI
SEMEMMKIIGKHKNIINLLGACTQD---GPLYVIVEFAAKGNLREYLRVRRPPGMEY----------------CYNPDQV
PVENMSIKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGR---LPVKWM
APEALFDRIYTHQS----DVWSFGVLL----WEIFTLGGSPYPGVP-VEELFKLLKEGHRMDRPSTCTHELYMMMRDCWH
AVPSQRPTFKQLVEDLDRTLSMTSNQ-----------------------------------------------EYLDLSV
S-LDQFSPNFPDTRSS-----------------TCSSGEDSVFSHDAGADEPCLPKFPPHPNRGVAFKKR----------
------------------------------
>Takifugu_rubripes_FGFR1
--------------------------------------------------------------------------------
-----FICSRTTVLYRALM--------------------QQHVQ------------------------------------
---------------LCERGV----------------------AVEAPLEMFTLYPGQPLDLSCPASDS---TQAVNWTK
DHVLVVDGE------HTRIRNGHLEIESVELSDSGLYACTTFG---NHSGLFNISVD-----------------------
--------------------------------------------------------------------------------
--------------V-LASSEDDEEDEE-------SSSEEA--------------------------KLLGSQKE-LPMA
PQWAH-----PEKMAKKLHAVPASKTVKFRCQASGNPTPTLKWYKNGREF-KRDHRIGGFKVRDHM--WTIIMEAVVPSD
KGNYTCVVENQYGSINHTYQLDVVE--RSPHRPILQAGLPANRTAVVGSDVEFECK-VFSDPQPHIQWLKHIEVNGSRHG
P-DGLPYVRILKTAGFNITDK---------------------------------EMEVLQLRNVSFDDAGKYTCLAGNSI
GFSHHSAWLTVF--------------------------------------------------------------------
------------------------------------EAVPHYPPANHT--YLEVVIYCVGFFLIVVMITVAIIVKIRTSS
-KKSD------FNSQVAVHKLAKSIPLRRQVT-----VSVDSGSSIHSGAMLVRP-SRLSSSGS------PMLSGVS--E
YELPQDPR--WELP-RD---RLVLGKPLGEG--CFGQVV-MGEAMGLDKEKPNRVT-KVAVKMLK---SDATEKDLSDLI
SEMEMMKIIGKHKNIINLLGACTQD---GPLYVIVEYASKGNLREYLRARRPPGMEY----------------CYNPDQV
PVENMSIKDLVSCAFQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGR---LPVKWM
APEALFDRIYTHQS----DVWSFGVLL----WEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSTCTHELYMMMRDCWN
AVPSQRPTFKQLVEDLDRCLAMTSNQ-----------------------------------------------EYLELSM
P-LDQC---YPDTRSS-----------------TCSSGEDSVFSHDAGAEEPCLPKFPPHSN-GAAIKKR----------
------------------------------
>Tetraodon_nigroviridis_FGFR1a
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------PSA----------------------ATEAPVEMFTLYSGERLDLSCAASDA---TQAVNWTK
DQALVVDGE------HTRIHNGHLEIESVELSDSGLYACTTFG---NHSGFFNIS-------------------------
--------------------------------------------------------------------------------
------------------ASEDDEEDEE-------SSSEEA--------------------------KLLGSQKE-LPMA
PQWAH-----PEKMAKKLHAVPASKTVKFRCQASGNPIPTLKWYKNGKEF-KREHRIGGFKVRDHM--WTIIMEAVVPSD
KGNYTCVVENQYGSINHTYQLDVVE--RSPHRPILQAGLPANRTAVVGSDVEFECK-VFSDPQPHIQWLKHIEVNGSRLG
P-DGLPYVRILKTAGFNTTDK---------------------------------EMEVLQLRNVSFEDAGKYTCLAGNSI
GFSYHSAWLTVF--------------------------------------------------------------------
------------------------------------EAVPHYPPANHT--YLEVVIYCVGFFFIAVMITIAIMVKIRTSS
-KKSD------FSSQVAVHKLAKSIPLHRQVT-----VSVDSGSSVHSGAMLVRP-SRLSSSGS------PMLSGVS--E
YELP-DPR--WELPPGD---RLVLGKPLGEG--CFGQVV-MGEAMGLDRDRPNWVT-KVAVKMLK---ADATEKDLSDLI
SEMEMMKIIGKHKNIINLLGACTQD---GPLYVIVEYASKGNLREYLRARRPPGMEY----------------CYNPYQV
PVENMSIKDLVSCAFQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGR---LPVKWM
APEALFDRIYTHQS----DVWSFGVLL----WEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSTCTHQLYMMMRDCWH
AVPAQRPTFKQLVEDLDRCLAVASNQ-----------------------------------------------EYLELTT
P-LDQC---YPDTRSS-----------------TCSSGEDSVFSHDAGAEEPCLPQLPPHAN-GAAVKKR----------
------------------------------
>Gasterosteus_aculeatus_FGFR1a
--------------------------------------------------------------------------------
MLMRPNILLCLVLFSQVLR--------------------TQSRP------------------------------------
---------------ANNDEA----------------------SVETQVELFTLYLGGSLDLSCSAKDS---PHAVNWTK
DHEAVVDGE------HTRIRGVQLVIEAVELTDSGLYACTTFG---NHSNYFNVT-------------------------
--------------------------------------------------------------------------------
-------------------AEDDDEEEE-------SSSEEA--------------------------KLLGSQKL-LPMA
PEWTH-----PEKMEKKLHAVPASKTVKFRCQASGNPTPSLKWYKNGKEF-KRDHRIGGFKVRDHV--WTIIMESAVPSD
KGNYTCLVENEYGSINHTYQLDVVEE-RSPHRPILQAGLPANRTAVVGSDVEFECK-VFSDPQPHIQWLKHEEFNGSRLG
P-DGLAYVRVLKSAGLNTTDK---------------------------------EMEVLQLRNVSFDDAGKYTCLAGNSI
GYSYHSAWLAVF--------------------------------------------------------------------
------------------------------------EAVPHYPPASDT--YLEVVIYCVGFFLIVVMIAIAILVKNRTSS
-KKSD------FNSPLAVHKLAKSIPLRRQVT-----VSVDSSSSIHSGVMLVRP-SRLSSSGS------PMLSGVS--E
YELPQDPR--WELP-RD---RLVLGKPLGEG--CFGLVV-MGEALGLDKEKQNRVT-KVAVKMLK---SDATEKDLSDLI
SEMEMMKIIGKHKNIINLLGACTQD---GPLYVIVEYASKGNLREYLRARRPPGMEY----------------CYNPDQV
PVETMSIKDLVSCAYQVARGMEYLSSKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGR---LPVKWM
APEALFDRIYTNQS----DVWSFGVLL----WEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSTCTHELYMMMRDCWH
AVPSHRPTFKQLVEDLDRCLAMTSNQ-----------------------------------------------EYLELSV
P-LDQYSPNYPDTRSS-----------------TCSSGEDSVFSHDAGAEEPCLPKFPPHSN-GAAIKKR----------
------------------------------
>Oryzias_latipes_FGFR1a
--------------------------------------------------------------------------------
-----HIIYWCFLILKCKL--------------------LLKPD------------------------------------
---------------GVLPSS----------------------SVDAQPELFTLHLGSRLVLSCSVKDS---LHAVNWTK
DQIAVVNGE------HVRINNGQLEIETVELSDSGLYTCTTFG---NHSLYFNVTVV-----------------------
--------------------------------------------------------------------------------
--------------YNLASSEDDDDEEE-------SSSEET--------------------------KLLGSQKL-MPMA
PQWID-----PEKMEKKLHAVPASKTVKFRCPASGNPIPTLKWYKNGREF-KKDHRIGGFKVREHM--WSIIMESVVPSD
KGNYTCVVENQYGSINHTYQLDVVE--RSPHRPILQAGLPANRSVVVGSDVEFHCK-VFSDPQPHIQWLKHIEVNGSGVG
P-DGLPHVKILKTAGLNTTDK---------------------------------EMEVLQLRNVSFGDAGQYTCLAGNSI
GFSHHTAWLTVL--------------------------------------------------------------------
------------------------------------EAVTQYPPTSHT--YLEVGIYCAGFFFIAVMVAIAVIIKIRSTS
-KKSD------FNSQLAVHKLAKSIPLRRQV-------SVDSSSSNHSGVMLVRP-SRLSSSAS------PMLSGVS--E
YELPQDPR--WEVP-RD---KLVLGKPLGEG--CFGQVM-MGEVLGLDKEKPNRVT-NVAVKMLK---SDATEKDLSDLI
SEMEMMKIIGKHKNIINLLGACTQD---GPLYVIVEYASKGNLREYLRARRPPGMEY----------------CYNPDQV
SVETMSIKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGR---LPVKWM
APEALFDRIYTHQS----DVWSFGVLL----WEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSTCTHELYMMMRDCWH
AVPSQRPTFKQLVEDLDRCLAMTSNQ-----------------------------------------------EYLELSV
P-LDQYSPSYPDTRSS-----------------TCSSGEDSVFSHDAGAEEPCLPKFPPHSN-GAAIKKR----------
------------------------------
>Ciona_savignyi_FGFR1
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
-------------------------------------------------------------------------------V
PTWTN-----KRKMQKKLHAEPAGNTVTFRCLVNGARPISVDWYKDGEKI-LKNDRLGGYKFRQKS--QCIVLETVILSD
RGMYMCVASNAYGSINHTYELDVAVR--MAIPPIVYSDEMKNQTVEIGQTATFRCK-IYSDAHPHIQWIK---FNGN---
-------ITALKKAGVNSTDA---------------------------------DLEKLTLKNVTFEDAGEYVCLAGNSF
GSTHASAWLTVIP-------------------------------------------------------------------
------------------------------------VLDKSDVEKNYIQSETHYLIYIFGVICFVILF-VFIIYMCNSHY
-QNKD------PPRLVPIENPDNIPRMT----------KMEQPVMLYGNEQAWRR---------------MCLPHADHIE
INIQPDLQ--WELK-RE---DILLHERIDEG--FFGQVF-RADLIRCNGGRKEKID--AAVKMLKN---TRTEKDMLDLL
TEMDQMKRIGKHKNIVN-LGVCTQNS---ILWLVTEYAQKGNLRDYLRRNRPSEMQYQFTNP---------D-PNAPPPP
RDEPLTYHALMSAAHQVARGMEYLSQKKCIHRDLAARNVLVTDEFVMKIADFGLARDVRCNDYYRKQTRGH---LPYKWM
AVEAMADNIFTPAT----DVWSFGVLL----WEIFSLGGSPYPGVK-THDLVRFLRSGDRLEQPQFASSELYRLMRDCWE
ESPNRRPKFRQLVEDLDRMLASASNVE-----------------------------------------------YIDLNS
PCEADYLPSDLDSEDET----------------ESSRDSANATGEDSDSVFEPIEQHGPHVYEVDEANPLLNHEPDSNIM
CNGHARMQSDV-------------------
>Branchiostoma_floridae_FGFR1
------------------------------------------------------------------------MGLCRCLQ
LRLLLAAMATAAMAAVTSTQD------------------ATPHPGGEGR-------------------------------
---------DVREGTRIFLSRG--------------------GCGRKETSMTKRLKLDGVPKRCSLAYLV-FSWNPTEIS
LNTLKALEM------KPVISKGSYNIPVVTYRVGTTHLWTTERDSDDNFSGDGILMDTIGAEG-----------------
--------------------------------------------------------------------------------
--------VDDLDVRDLAALRDAGDDEDY------AADEEE--------------------------DEPGMIHDDAPHA
PVWQK------PEDNQKIIAAPAGNTVKMRCPATGNPRPTIRWLKDKQEF-RESDRMEGYKIRNKH--WSLVMTGIVPSD
EGFYTCIIQNDYGSINHTYELDVIER--SPSRPILAPGLPQNQTVVVGSTVDFQCK-VFSDAQPHIQWLKHYEVNGSYVD
A-NGKPHVRVLKSSSMDFSDTDTIPIDDTSGI------------------GKTDAAEKLIIRNVEQSDAGKYTCRAESYL
GSVNQSAWLFVFKEYPTPP-------------------------------------------------------------
-----------------------------------TVETRKPVQPDKYDIAAEIAVYSVGGVFLLTIFAFVAIYYFRFKR
-KQVP------KSNEPPLCQLKKPLHLKRQVS-------LESSSSINSNAPLVRLRSTR--LSS-------SLGGVT--E
YELPLDPD--WEFP-RD---R-----------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------
>Hydra_magnipapillata_FGFR1
--------------------------------------------------------------------MISDWCVVLVLS
ISKLVFGLN-----------------------------------------------------------------------
------------------------------------------FTEPVNYILKIGENNSSRLLDCSVGLSVELIKKIDWTY
NGIVINKKPN----VTFTDKGQKLIIGHYKPHNSGRYGCKITAVSEESVERIFDLLP-----------------------
--------------------------------------------------------------------------------
--------------TSVICFYFIIDLMPR---------------------------------------------------
-----------IKNDISLLVELVMNKLDLDCTAVGASPISITWLKNDKLI-EARS---NLRYSFSPNFLKLSIKEVRLDD
AGIYKCILENKYGKIEHVMTVEIYEK---VFSKPIIYSTDKHKVFYADYGQNLTVPVYVTAFLPYPHFEMLYVYNKTIPN
TNETKINVRKRPTFRELTVLEISQRKGTSIN----------------------HIRLDYFFTNISEQDFGNYTLMAGNKY
GYDRYPFQILHTKYMQTTVSPP----------------------------------------------------------
-----------------------------------MKANINKIYKEESVEKTVIFIVIASMLAGLIFVAFFFFFICRVRS
KEKFK-------NSNINYIKPSQTVILNLGDN-------NTSGVTMVTSVSAFSYANRRFRHSLN----NNPVNDKQKYN
LKIAPDPA--WEIKLEQ----LETDCLLGEG--AFGRVF---RATARDLPNRTGVQ-TVAVKMLK---EDCCEQDLKDFI
SEIEVMKSIGKHINILNLLAVSSQQG---KLYIVVEYCRHGNLRSFLKDNRPV--TQANS---------------VITKK
----ITSYDLMSFCLQVARGMNYLASKKCIHRDIAARNVLVGEGYLLKVADFGLARDVREHDYYRKCT-DGR--LPVKWM
AIEALFDRVYTTQS----DIWSFGILA----WEIVTFGGSPYPGIA-LENMFDLLKQGYRMEKPPNCTDDMYALMLNCWK
EIPSKRPTFSQLIEDLERMLLNASST-----------------------------------------------EYIDLQP
IQPERAELFSTSIHTSTS-------------MLNTDLFNKNKYDHDEVSFTHEDGLSEADVLLNYQVVS-----------
------------------------------
>Homo_sapiens_FGFR2
--------------------------------------------------------------------------------
MVSWGR--FICLVVVTMATL-------------------SLARPSFS---------------------------------
----------LVEDTTLEPEE------------------PPTKYQISQPEVYVAAPGESLEVRCLLKD----AAVISWTK
DGVHLGPNN------RTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVT-----------------------
--------------------------------------------------------------------------------
--------------DAISSGDDEDDTDG---------AEDF--------------------------VSENSNNK---RA
PYWTN-----TEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEF-KQEHRIGGYKVRNQH--WSLIMESVVPSD
KGNYTCVVENEYGSINHTYHLDVVER--SPHRPILQAGLPANASTVVGGDVEFVCK-VYSDAQPHIQWIKHVEKNGSKYG
P-DGLPYLKVLKHSGINSSN-----------------------------------AEVLALFNVTEADAGEYICKVSNYI
GQANQSAWLTVLPK------------------------------------------------------------------
-----------------------------------QQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTT
-KKPD------FSSQPAVHKLTKRIPLRRQVT-----VSAESSSSMNSNTPLVRITTRLSSTADT-----PMLAGVS--E
YELPEDPK--WEFP-RD---KLTLGKPLGEG--CFGQVV-MAEAVGIDKDKPKEAV-TVAVKMLK---DDATEKDLSDLV
SEMEMMKMIGKHKNIINLLGACTQD---GPLYVIVEYASKGNLREYLRARRPPGMEY----------------SYDINRV
PEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGR---LPVKWM
APEALFDRVYTH----QSDVWSFGVLM----WEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPANCTNELYMMMRDCWH
AVPSQRPTFKQLVEDLDRILTLTTN-----------------------------------------------EEYLDLSQ
P-LEQYSPSYPDTRS------------------SCSSGDDSVFSPDPMPYEPCLPQYP--HINGSVKT------------
------------------------------
>Pan_troglodytes_FGFR2
--------------------------------------------------------------------------------
MVSWGR--FICLVVVTMATL-------------------SLARPSFS---------------------------------
----------LVEDTTLEPEE------------------PPTKYQISQPEVYVAAPGESLEVRCLLKD----AAVISWTK
DGVHLGPNN------RTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVT-----------------------
--------------------------------------------------------------------------------
--------------DAISSGDDEDDTDG---------AEDF--------------------------VSENSNNK---RA
PYWTN-----TEKMEKRLHAVPAANTVKFRCPAGGNPTPTMRWLKNGKEF-KQEHRIGGYKVRNQH--WSLIMESVVPSD
KGNYTCVVENEYGSINHTYHLDVVER--SPHRPILQAGLPANASTVVGGDVEFVCK-VYSDAQPHIQWIKHVEKNGSKYG
P-DGLPYLKVLKHSGINSSN-----------------------------------AEVLALFNVTEADAGEYICKVSNYI
GQANQSAWLTVLPK------------------------------------------------------------------
-----------------------------------QQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTT
-KKPD------FSSQPAVHKLTKRIPLRRQVT-----VSAESSSSMNSNTPLVRITTRLSSTADT-----PMLAGVS--E
YELPEDPK--WEFP-RD---KLTLGKPLGEG--CFGQVV-MAEAVGIDKDKPKEAV-TVAVKMLK---DDATEKDLSDLV
SEMEMMKMIGKHKNIINLLGACTQD---GPLYVIVEYASKGNLREYLRARRPPGMEY----------------SYDINRV
PEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGR---LPVKWM
APEALFDRVYTH----QSDVWSFGVLM----WEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPANCTNELYMMMRDCWH
AVPSQRPTFKQLVEDLDRILTLTTN-----------------------------------------------EEYLDLSQ
P-LEQYSPSYPDTRS------------------SCSSGDDSVFSPDPMPYEPCLPQYP--HINGSVKT------------
------------------------------
>Gorilla_gorilla_FGFR2
------------------------------------------------------------MGLTSTWRYGRGPGIGTVT-
MVSWGR--FICLVVVTMATL-------------------SLARPSFS---------------------------------
----------LVEDTTLEPEE------------------PPTKYQISQPEVYVAAPGESLEVRCLLKD----AAVISWTK
DGVHLGPNN------RTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVT-----------------------
--------------------------------------------------------------------------------
--------------DAISSGDDEDDTDG---------AEDF--------------------------VSENSNNK---RA
PYWTN-----TEKMEKRLHAVPAANTVKFRCPAGGNPTPTMRWLKNGKEF-KQEHRIGGYKVRNQH--WSLIMESVVPSD
KGNYTCVVENEYGSINHTYHLDVVER--SPHRPILQAGLPANASTVVGGDVEFVCK-VYSDAQPHIQWIKHVEKNGSKYG
P-DGLPYLKVLKHSGINSSN-----------------------------------AEVLALFNVTEADAGEYICKVSNYI
GQANQSAWLTVLPK------------------------------------------------------------------
-----------------------------------QQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTT
-KKPD------FSSQPAVHKLTKRIPLRRQVT-----VSAESSSSMNSNTPLVRITTRLSSTADT-----PMLAGVS--E
YELPEDPK--WEFP-RD---KLTLGKPLGEG--CFGQVV-MAEAVGIDKDKPKEAV-TVAVKMLK---DDATEKDLSDLV
SEMEMMKMIGKHKNIINLLGACTQD---GPLYVIVEYASKGNLREYLRARRPPGMEY----------------SYDINRV
PEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGR---LPVKWM
APEALFDRVYTH----QSDVWSFGVLM----WEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPANCTNELYMMMRDCWH
AVPSQRPTFKQLVEDLDRILTLTTN-----------------------------------------------EEYLDLSQ
P-LEQYSPSYPDTRS------------------SCSSGDDSVFSPDPMPYEPCLPQYP--HINGSVKT------------
------------------------------
>Macaca_mulatta_FGFR2
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------------------------------------GA
PYWTN-----TEKMEKRLHAVPAANTVKFRCPAGGNPTPTMRWLKNGKEF-KQEHRIGGYKVRNQH--WSLIMESVVPSD
KGNYTCVVENEYGSINHTYHLDVVER--SPHRPILQAGLPANASTVVGGDVEFVCK-VYSDAQPHIQWIKHVEKNGSKYG
P-DGLPYLKVLKHSGINSSN-----------------------------------AEVLALFNVTEADAGEYICKVSNYI
GQANQSAWLTVLPK------------------------------------------------------------------
-----------------------------------QQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTT
-KKPD------FSSQPAVHKLTKRIPLRRQV-------SAESSSSMNSNTPLVRITTRLSSTADT-----PMLAGVS--E
YELPEDPK--WEFP-RD---KLTLGKPLGEG--CFGQVV-MAEAVGIDKDKPKEAV-TVAVKMLK---DDATEKDLSDLV
SEMEMMKMIGKHKNIINLLGACTQD---GENGWASRSCSQSTPHEHKEGSVPAGLEFLT--------------SSDPSTL
TSQSVGITGMSHCTQPHS--VSYSILQLCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGR---LPVKWM
APEALFDRVYTH----QSDVWSFGVLM----WEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPANCTNELYMMMRDCWH
AVPSQRPTFKQLVEDLDRILTLTTN-----------------------------------------------EEYLDLSQ
P-LEQYSPSYPDTRS------------------SCSSGDDSVFSPDPMPYEPCLPQYP--HINGSVKT------------
------------------------------
>Mus_musculus_FGFR2
--------------------------------------------------------------------------------
MVSWGR--FICLVLVTMATL-------------------SLARPSFS---------------------------------
----------LVEDTTLEPEE------------------PPTKYQISQPEAYVVAPGESLELQCMLKD----AAVISWTK
DGVHLGPNN------RTVLIGEYLQIKGATPRDSGLYACTAARTVDSETWYFMVNVT-----------------------
--------------------------------------------------------------------------------
--------------DAISSGDDEDDTDS---------SEDV--------------------------VSENRSNQ---RA
PYWTN-----TEKMEKRLHAVPAANTVKFRCPAGGNPTPTMRWLKNGKEF-KQEHRIGGYKVRNQH--WSLIMESVVPSD
KGNYTCLVENEYGSINHTYHLDVVER--SPHRPILQAGLPANASTVVGGDVEFVCK-VYSDAQPHIQWIKHVEKNGSKYG
P-DGLPYLKVLKHSGINSSN-----------------------------------AEVLALFNVTEMDAGEYICKVSNYI
GQANQSAWLTVLPK------------------------------------------------------------------
-----------------------------------QQAPVREKEITASPDYLEIAIYCIGVFLIACMVVTVIFCRMKTTT
-KKPD------FSSQPAVHKLTKRIPLRRQVT-----VSAESSSSMNSNTPLVRITTRLSSTADT-----PMLAGVS--E
YELPEDPK--WEFP-RD---KLTLGKPLGEG--CFGQVV-MAEAVGIDKDKPKEAV-TVAVKMLK---DDATEKDLSDLV
SEMEMMKMIGKHKNIINLLGACTQD---GPLYVIVEYASKGNLREYLRARRPPGMEY----------------SYDINRV
PEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGR---LPVKWM
APEALFDRVYTH----QSDVWSFGVLM----WEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPTNCTNELYMMMRDCWH
AVPSQRPTFKQLVEDLDRILTLTTN-----------------------------------------------EEYLDLTQ
P-LEQYSPSYPDTRS------------------SCSSGDDSVFSPDPMPYEPCLPQYP--HINGSVKT------------
------------------------------
>Oryctolagus_cuniculus_FGFR2
------------------------------------------------------------MGFTSTWRYGRGPGIGTVT-
MVGWGR--FICLVMVTMATV-------------------SLARPSFN---------------------------------
----------LVEDATVEPEE------------------PPTKYQISQPEVYVAAPGESLELRCLLKD----ASVISWTK
DGVHLGPNN------RTVLIGEYLQIRGATPRDSGLYACTAARTVDSDTWYFMVNVT-----------------------
--------------------------------------------------------------------------------
--------------DAISSGDDEDDTDG---------AEDF--------------------------VSENSNSK---RA
PYWTN-----TEKMEKRLHAVPAANTVKFRCPAGGSPTPTMRWLKNGKEF-KQEHRIGGYKVRNQH--WSLIMESVVPSD
KGNYTCVVENEYGSINHTYHLDVVER--SPHRPILQAGLPANASTVVGGDVEFVCK-VYSDAQPHIQWIKHVEKNGSKYG
P-DGLPYLKVLKHSGINSSN-----------------------------------AEVLALFNVTEADAGEYICKVSNYI
GQANQSAWLTVLPK------------------------------------------------------------------
-----------------------------------QQAPVREKEITASPDYLEIAIYCIGVFLIVCMVITVIVCRMKTTS
-KKPD------FSSQPAVHKLTKRIPLRRQVT-----VSAESSSSMNSNTPLVRITTRLSSAADT-----PMLAGVS--E
YELPEDPK--WEFP-RD---KLTLGKPLGEG--CFGQVV-MAEAVGIDKDKPKEAV-TVAVKMLK---DDATEKDLSDLV
SEMEMMKMIGKHKNIINLLGACTQD---GPLYVLVEYASKGNLREYLRARRPPGMEY----------------SYDINRV
PEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGR---LPVKWM
APEALFDRVYTH----QSDVWSFGVLM----WEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPANCTNELYMMMRDCWH
AVPSQRPTFKQLVEDLDRILTLTTN-----------------------------------------------EEYLDLSQ
P-LEQYSPSYPDSRS------------------SCSSGDDSVFSPDPMPYEPRLPQYP--HVNGSVQT------------
------------------------------
>Equus_caballus_FGFR2
--------------------------------------------------------------------------------
MVSWGR--FICLVVVTMATL-------------------SLARPSFN---------------------------------
----------LVEDTTLEPEE------------------PPTKYQISQPEVYVAAPGESLELRCLLRD----AAMISWTK
DGVHLGPSN------RTVLIGEYLQIKGATPRDSGLYACTAARTVDSETVYFMVNVT-----------------------
--------------------------------------------------------------------------------
--------------DAISSGDDEDDTDG---------SEDF--------------------------VSESSNNK---RA
PYWTN-----TEKMEKRLHAVPAANTVKFRCPAGGNPTPTMRWLKNGKEF-KQEHRIGGYKVRNQH--WSLIMESVVPSD
KGNYTCVVENEYGSINHTYHLDVVER--SPHRPILQAGLPANASTVVGGDVEFVCK-VYSDAQPHIQWIKHVEKNGSKYG
P-DGLPYLKVLKHSGINSSN-----------------------------------AEVLALFNVTEADAGEYICKVSNYI
GQANQSAWLTVLPK------------------------------------------------------------------
-----------------------------------QQAPVREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKTTT
-KKPD------FSSQPAVHKLTKRIPLRRQVF-----VSAESSSSMNSNTPLVRITTRLSSTADT-----PMLAGVS--E
YELPEDPK--WEFP-RD---KLTLGKPLGEG--CFGQVV-MAEAVGIDKEKPKEAV-TVAVKMLK---DDATEKDLSDLV
SEMEMMKMIGKHKNIINLLGACTQD---GPLYVIVEYASKGNLREYLRARRPPGMEY----------------SYDINRV
PEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGR---LPVKWM
APEALFDRVYTH----QSDVWSFGVLM----WEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPANCTNELYMMMRDCWH
AVPSQRPTFKQLVEDLDRILTLTTN-----------------------------------------------EEYLDLSQ
P-LEQYSPSYPDTRS------------------SCSSGDDSVF----LCYDPCLPQYP--HINGSVKT------------
------------------------------
>Dasypus_novemcinctus_FGFR2
------------------------------------------------------------MGLTSTWRHGRGSGLGTVT-
MVSWGR--FVCLVAVTMATV-------------------SLARPSFN---------------------------------
----------LVEDTTFEPEE------------------PPTKYQISQPDVYVAAPGESLELRCLLKD----AAMISWTK
DGVHLGPNN------RTVLIGEYLQIKGATSRDSGLYTCTAARTVDSETLYFIVNVT-----------------------
--------------------------------------------------------------------------------
--------------DAISSGDDEDDTDG---------PEDF--------------------------VSEN-NNK---RA
PYWTN-----TEKMEKRLHAVPAANTVKFRCPAGGNPTPTMRWLKNGKEF-KQEHRIGGYKVRNQH--WSLIMESVVPSD
KGNYTCVVENEYGSINHTYHLDVVER--SPHRPILQAGLPANASAVVGGDVEFVCK-VYSDAQPHIQWIKHVEKNGSKYG
P-DGLPYLKVLKHSGINSSN-----------------------------------AEVLALFNVTEADAGEYICKVSNYI
GQANQSAWLTVLPK------------------------------------------------------------------
-----------------------------------QQAPVREKEITSSPDYLEIAIYCIGVFLIACMVVTVILCRMKTTT
-KKPD------FGSQPAVHKLTKRIPLRRQVT-----VSAESSSSMNSNTPLVRITTRLSSTADT-----PMLAGVS--E
YELPEDPK--WEFP-RD---KLTLGKPLGEG--CFGQVV-MAEAVGIDKDKPKEAV-TVAVKMLK---DDATEKDLSDLV
SEMEMMKMIGKHKNIINLLGACTQD---GPLYVIVEYASKGNLREYLRARRPPGMEY----------------SYDINRV
PEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGR---LPVKWM
APEALFDRVYTH----QSDVWSFGVLM----WEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPANCTNELYMMMRDCWH
AVPSQRPTFKQLVEDLDRILTLTTN-----------------------------------------------EEYLDLSQ
P-LEQYSPSYPDTRS------------------SCSSGDDSVFSPDPMPYEPCLPQYP--HANGSVKT------------
------------------------------
>Pteropus_vampyrus_FGFR2
------------------------------------------------------------MGLTSTWRYGRGRGIGTVT-
MVSWGR--FVCLVVVTMATS-------------------SLARPS-N---------------------------------
----------LVKDTTLEPEE------------------PPTKYQISQPEVYVAAPGDSLELRCQLRD----AAVISWTK
DGGQLGPSN------RTVLIGEYLQIEGATPRDSGLYACTAARTVDSETVYFMVNVT-----------------------
--------------------------------------------------------------------------------
--------------DAISSGDDEDDTDG---------SEDF--------------------------VSENRDNK---RA
PYWTN-----TEKMEKRLHAVPAANTVKFRCPAGGNPTPTMRWLKNGKEF-KQEHRIGGYKVRNQH--WSLIMESVVPSD
KGNYTCVVENEYGSINHTYHLDVVER--SPHRPILQAGLPANASTVVGGDVEFVCK-VYSDAQPHIQWIKHVEKNGSKYG
P-DGLPYLKVLKHSGINSSN-----------------------------------AEVLALFNVTEADAGEYICKVSNYI
GQANQSAWLTVLPK------------------------------------------------------------------
-----------------------------------QQAPVREKEITTSPDYLEIAIYCIGVFLIACMVVTVIVCRMKTTT
-KKPD------FSSQPAVHKLTKRIPLRRQVT-----VSAESSSSMNSNTPLVRITTRLSSTADT-----PMLAGVS--E
YELPEDPK--WEFP-RD---KLTLGKPLGEG--CFGQVV-MAEAVGIDKEKPKEAV-TVAVKMLK---DDATEKDLSDLV
SEMEMMKMIGKHKNIINLLGACTQD---GPLYVIVEYASKGNLREYLRARRPPGMEY----------------SYDINRV
PEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGR---LPVKWM
APEALFDRVYTH----QSDVWSFGVLM----WEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPANCTNELYMMMRDCWH
AVPSQRPTFKQLVEDLDRVLTLTAN-----------------------------------------------EEYLDLSQ
P-LEQYSPSFPDTRS------------------SCSSGDDSVFSPDPMPYEPCLPQYP--HINGSVKT------------
------------------------------
>Gallus_gallus_FGFR2
------------------------------------------------------------MGLKSTWRYGNGPGTYSKK-
MVSWDSGCLICLVVVTMAGL-------------------SLARPSFNL--------------------------------
----------VVEDATLEPEE------------------PPTKYQISQPDVHSALPGEPLELRCQLKD----AVMISWTK
DGVPLGPDN------RTVIIGEYLQIKDASPRDSGLYACTAIRTLDSDTLYFIVNVT-----------------------
--------------------------------------------------------------------------------
--------------DALSSGDDEDDNDG---------SEDF--------------------------VNDS-NQM---RA
PYWTH-----TDKMEKRLHAVPAANTVKFRCPAMGNPTPTMRWLKNGKEF-KQEHRIGGYKVRNQH--WSLIMESVVPSD
KGNYTCIVENQYGSINHTYHLDVVER--SPHRPILQAGLPANASAVVGGDVEFVCK-VYSDAQPHIQWIKHVERNGSKYG
P-DGLPYLQVLKAAGVNTTDK---------------------------------EIEVLYIRNVTFEDAGEYTCLAGNSI
GISFHTAWLTVLP-------------------------------------------------------------------
-------------------------------------APEKEKEFPTSPDYLEIAIYCIGVFLIACMVLTVILCRMKNTT
-KKPD------FSSQPAVHKLTKRIPLRRQVT-----VSADSSSSMNSNTPLVRITTRLSSTADA-----PMLAGVS--E
YELPEDPK--WEFP-RD---KLTLGKPLGEG--CFGQVV-MAEAVGIDKDRPKEAV-TVAVKMLK---DDATEKDLSDLV
SEMEMMKMIGKHKNIINLLGACTQD---GPLYVIVEYASKGNLREYLRARRPPGMEY----------------SFDINRV
PEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGR---LPVKWM
APEALFDRVYTH----QSDVWSFGVLM----WEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPANCTNELYMMMRDCWQ
AVPSQRPTFKQLVEDLDRILTLTTN-----------------------------------------------EEYLDLSG
P-LEQYSPSYPDTRS------------------SCSSGDDSVFSPDPMPYEPCLPKYQ--HMNGSVKT------------
------------------------------
>Taeniopygia_guttata_FGFR2
------------------------------------------------------------MGLKSTWRYGNGPGIYSKK-
MVRWDSGCLICLVVVTMAGL-------------------SLARPSFNL--------------------------------
----------VVEDTTVEPEE------------------PPTKYQISQPDVYSALPGETLELRCQLRD----AVMISWTK
DGLPLGPDN------RTVIIGEYLQIKDATARDSGLYACTAVRTLDSDTLYFIVNVT-----------------------
--------------------------------------------------------------------------------
--------------DALSSGDDEDDNDG---------SEDF--------------------------VNDS-NQM---RA
PYWTH-----TDKMEKRLHAVPAANTVKFRCPAMGNPTPTMRWLKNGKEF-KQEHRIGGYKVRNQH--WSLIMESVVPSD
KGNYTCIVENQYGSINHTYHLDVVER--SPHRPILQAGLPANASAVVGGDVEFVCK-VYSDAQPHIQWIKHVEKNGSKYG
P-DGLPYLQVLKAAGVNTTDK---------------------------------EIEVLYIRNVTFEDAGEYTCLAGNSI
GISFHTAWLTVLP-------------------------------------------------------------------
-------------------------------------APEKEKEYPTSPDYVEIAIYCIGVFLIACMVLTVILCRMKNTT
-KKPD------FSSQPAVHKLTKRIPLRRQV-------SADSSSSMNSNTPLVRITTRLSSAADA-----PMLAGVS--E
YELPEDPK--WEFP-RD---KLTLGKPLGEG--CFGQVV-MAEAVGIDKDRPKEAV-TVAVKMLK---DDATEKDLSDLV
SEMEMMKMIGKHKNIINLLGACTQD---GPLYVIVEYASKGNLREYLRARRPPGMEY----------------SFDINRV
PEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGR---LPVKWM
APEALFDRVYTH----QSDVWSFGVLM----WEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPANCTNELYMMMRDCWH
AVPSHRPTFKQLVEDLDRILTLTTN-----------------------------------------------EEYLDLSG
P-LEQYSPSYPDTRS------------------SCSSGDDSVFSPDPMPYEPCLPKYQ--HMNGSVKT------------
------------------------------
>Anolis_carolinensis_FGFR2
------------------------------------------------------------MGLKSTWRYGRGPGTGTEK-
MVSWDSCCLICLVVITMAGF-------------------SLARPSYNL--------------------------------
----------VGEDTTLEPEE------------------PPTKYQISQPEAHTVLPGETLKLHCQLKD----ATMITWTK
DGVHLVPNN------RTIISGEYLWIKDTTPRDSGLYACT----VDSETLYFITNIT-----------------------
--------------------------------------------------------------------------------
--------------DVLSSGDDEDDNDG---------SEDF--------------------------VNDN-NPI---KG
PKWTQ-----TDKMEKRLHAVPAANTVKFRCPATGNPMPTMRWLKNGKEF-KQEHRIGGYKVRNQH--WSLIMESVVPSD
KGNYTCIVENIHGSINHTYHLDVVER--SPHRPILQAGLPANTSAILGGEAKFVCK-VYSDAQPHIQWIKHIEKNGSKYG
P-DGLPYLEVLKHSGINSSN-----------------------------------TEVLKLHNVTEEDAGEYICKVSNYI
GEANQSAWLVVLP-------------------------------------------------------------------
-----------------------------------DKAPVEDRPYPTSPDYLEIAIYCVGVFLIVCMVMTVILCRMRSTT
-KKSD------FSSQPAVHKLTKRIPLRRQVT-----VSADSSSSMNSNTPLVRITTRLSSNTDA-----PMLAGVS--E
YELPEDPK--WEFP-RD---KLTLGKPLGEG--CFGQVV-MAEAVGIDKDRPKEAV-TVAVKMLK---DDATEKDLSDLV
SEMEMMKMIGKHKNIINLLGACTQD---GPLYVLVEYASKGNLREYLRARRPPGMEY----------------SFDINRV
PEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGR---LPVKWM
APEALFDRVYTH----QSDVWSFGVLM----WEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPANCTNELYMMMRDCWH
AVPSQRPTFKQLVEDLDRILTLTTN-----------------------------------------------EEYLDLSG
P-LEQYSPSYPDTRS------------------SCSSGDDSVFSPDPMPYEPCLPKYQ--HINGSVKT------------
------------------------------
>Danio_rerio_FGFR2
--------------------------------------------------------------------------------
-MFARGWLLGALLLMTLATV-------------------SVARPSLKID-------------------------------
----------LVN--TSAPEE------------------PPTKNQNCVPVLFSVHPGELLKLKCPLSG----ADDVVWTK
DSSSLRPDN------RTLVTRDWLQISDATPKDSGLYSCSATGSRDCDVFSFIVNVT-----------------------
--------------------------------------------------------------------------------
--------------DAISSGDDEDDTER---------SDDV--------------------------GADGEQM----RL
PYWTF-----PEKMEKKLHAVPAANTVKFRCAAAGNPKPKMRWLKNAKPF-RQEDRMGGYKVRLQH--WTLIMESVVPSD
KGNYTCLVENQYGSINHTYTLDVVER--SPHRPILQAGLPANVTVQVGQDAKFVCK-VYSDAQPHIQWLQHYTKNGSRYG
P-DGLPYVRVLKSSGINSSD-----------------------------------VEVLMLTNVTEEDAGEITCKVSNYI
GEANNSCWLIVIPA------------------------------------------------------------------
-----------------------------------E---TNPIETDYPPDYVEIAIYCIGVFLIACMVVIVVVCRMRTSA
-KKPD------FSSQPAVHKLTKQIPLRRQVT-----VSSDSSSSMSSSTPLVRITTRR-SSAHD-----DPIP-----E
YDLPEDPR--WEFS-RD---KLTLGKPLGEG--CFGQVV-MAEALGIDKDKPKEAV-TVAVKMLK---DDATEKDLSDLV
SEMEMMKMIGRHKNIINLLGACTQD---GPLYVIVEYASKGNLREYLRARRPPGMEY----------------SYDIARV
SDEPLTFKDLVSCTYQVARGMEYLASQKCIHRDLAARNVLVTESNVMKIADFGLARDVHNIDYYKKTTNGR---LPVKWM
APEALFDRVYTH----QSDVWSFGVLM----WEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPANCTNELYMMMKDCWH
AISSHRPTFKQLVEDLDRILTLATN-----------------------------------------------EEYLDLCA
P-VEQYSPSFPDTRS------------------SCSSGDDSVFSHDPLADEPCLPKYQ--HINGGIKT------------
------------------------------
>Takifugu_rubripes_FGFR2
--------------------------------------------------------------------------------
-MSSWAWLLAAVLVS-LLTA-------------------SVARPPLTAA-------------------------------
----------KEEEATQRPED------------------TSNKYQISKPTVCSVHPGEVLKLSCPLPA----TGTISWTK
DGSSLGANN------RTLIEQEVLQIRDATPKDSGLYTCTSVGK---DTVCFIVNVT-----------------------
--------------------------------------------------------------------------------
--------------DAISSGDDEDDTER---------SEDS--------------------------GADGEQPTL--GA
PYWIS-----SAKMEKKLHAVPAANTVKFRCAAGGNPEPKLRWLKNNRPF-RQEDRMGGYKVRNQH--WTLIMESVVPSD
KGNYTCLVENEFGSINHTYTLDVVER--SPHRPILQAGLPANTTVHVGEDARFVCK-VYSDAQPHIQWLKHIAQNGSRFG
P-DGNPYVRVLKRSGINSSD-----------------------------------VEILTLTNVTEEDAGEYICKVSNYI
GEASQSGWLTVIPE------------------------------------------------------------------
-----------------------------------RETSIEESHGPLSPHYVEIAIYCAGVFLIACMVGIVVVCRMRNTT
-KKPD------FGGQPAVHKLSKQIPLRRQVT-----VSADSSSSMNSNTPLVRITTRR-SSAHD-----EPIP-----E
YDLPEDPR--WEFT-RD---RLTLGKPLGEG--CFGQVV-MAEALGVDKDKPKEAV-TVAVKMLK---DDATEKELSDLV
SEMEMMKMIGKHKNIINLLGACTQD---GPLYVIVEYASKGNLREYLRARRPPGMEY----------------SYDIARV
SDEQLTFKDLVSCTYQVARGMEYLASQKCIHRDLAARNVLVTESNIMKIADFGLARDVHNIDYYKKTTNGR---LPVKWM
APEALFDRVYTH----QSDVWSFGVLM----WEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPGNCTNELYMMMKDCWH
AISSQRPTFKQLVEDLDRILTLSSNE----------------------------------------------EYLDLCIP
--SEQYSPSFPDTRS------------------SCSSGDDSVFSHDPLPDEPCLPKYQ--HINGNVKT------------
------------------------------
>Tetraodon_nigroviridis_FGFR2a
--------------------------------------------------------------------------------
-MALWAWLLAAVLLS-LLTA-------------------SVARPPLTAA-------------------------------
----------KEAEVTQEPED------------------TSNKNQISKPTVCSVHPGEVLKLSCPLPA----TGTITWTK
DGSSLGANN------RTLIEQEVLQIRDATPRDSGLYTCTSVGK---DTVCFIVNVT-----------------------
--------------------------------------------------------------------------------
--------------DATSSGDDEDDTER---------SEDS--------------------------GAEAEQP----SA
PYWIS-----PEKMEKKLHAVPAANTVKFRCAAGGNPEPKLRWLKNNRPF-RQEDRMGGYKVRSQH--WTLIMESVVPSD
KGNYTCLVENEYGSINHTYFLDVVER--SPHRPILQAGLPANTTVHVGEDARFVCK-VYSDAQPHIQWLKHISQNGSSVG
P-DGNAYVRVLKTAGVNTTDK---------------------------------EIEVLYLHNVTFEDAGEYTCLAGNSI
GLSHQTAWLTVLPA------------------------------------------------------------------
-----------------------------------R----EESQDPLSPHYVEIAIYCAGVFLIACMVGIVVVCRMRNTT
-KKPD------FGGQPAVHKLSKQIPLRRQVT-----VSADSSASMNSNTPLVRIMTRR-SIAHD-----EPIP-----E
YDLPEDPR--WEFA-RD---RLTLGKPLGEG--CFGQVV-MAEALGIDKDKPKEAV-TVAVKMLK---DDATEKELSDLV
SEMEMMKMIGKHKNIINLLGACTQD---GPLYVIVEYASKGNLREYLRARRPPGMEY----------------SYDIARV
SDEQLTFKDLVSCTYQVARGMEYLASQKCIHRDLAARNVLVTESNIMKIADFGLARDVHNIDYYKKTTNGR---LPVKWM
APEALFDRVYTH----QSDVWSFGVLM----WEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPGNCTNELYMMMKDCWH
AISSQRPTFKQLVEDLDRILALSSNE------------------------------------------------------
-------VSLPQP-------------------------------------------------------------------
------------------------------
>Gasterosteus_aculeatus_FGFR2b
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
------------------------------------------------PTLCSVHPGELLKLSCPLSP----PGTITWTK
DGSSVGTNN------RTVIEQEVLQIRDATAKDSGLYTCTSVGK---KTVCFIVNVT-----------------------
--------------------------------------------------------------------------------
--------------DAISSGDDEDDSER---------SEDT--------------------------GVDEEQI----SA
PFWTS-----TAKMEKRLHAVPAANTVKFRCAAGGNPRPKMRWLKNSRPF-RQEDRMGGYKVRSQH--WTLIMESVVPSD
KGNYTCLVENEFGAINHTYTLDVVER--SPHRPILQAGLPANITVHVGEDARFVCK-VYSDAQPHIQWLKHISRNGSRYG
P-DGHPYVQVLKTAGVNTTDK---------------------------------EIEALYLPNVTFEDSGEYTCLAGNSI
GISYHTAWLTVLP-------------------------------------------------------------------
--------------------------------------AIEKSIGPFSPDYVEIAIYCAGVFLIACMVGIVVVCRMRNTA
-KKPD------FGGQPAVHKLSKQIPLRRQV-------SADSSSSMNSSTPLVRITTRR-SSAHD-----DRIP-----E
YDLPEDPC--WEFS-RD---RLTLGKPLGEG--CFGQVV-MAEALGIDKDKTKDAV-TVAVKMLK---DDATEKDLSDLV
SEMEMMKMIGKHKNIINLLGACTQE---GPLYVIVEYASKGNLREY--------MEY----------------SYDIARV
SDEQLTFKDLVSCTYQVARGMEYLASQKCIHRDLAARNVLVTESNFMKIADFGLARDVHNIDYYKKTTNGR---LPVKWM
APEALFDRVYTH----QSDVWSFGVLM----WEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPGNCTNELYMMMKDCWH
AISSHRPTFKQLVEDLDRILSLNTNE----------------------------------------------EESVDLC-
--------------------------------------------------------------------------------
------------------------------
>Oryzias_latipes_FGFR2
------------------------------------------------------------------------LFLTLWLL
SSSFFFFTLCTLFLL-YFTL-------------------LSPHPPLSFT-------------------------------
----------PSPPPVCS-AE------------------ASNKYQISKPTVCSVHPGEALRLSCPLPA----TGTITWTK
DGSSLGTNN------HTVIEQDVLQIRDATPKDSGLYACTSVGK---DTVFFIVNVT-----------------------
--------------------------------------------------------------------------------
--------------DAISSGDDEDDTER---------SEDT--------------------------GLDGVQS----RP
PYWTS-----PAKMEKRLHAVPAANTVKFRCAAGGNPRPSLRWLKNQKPF-RQEDRMGGYKVRSQH--WTLLMESVVPSD
KGNYTCVVENELGSINHTYTLDVVER--SPHRPILQAGLPANTTVHVGEDARFVCK-VYSDAQPHIQWLKHITQNGSRLG
P-DGHPYVRVLKTAGVNTTDK---------------------------------EIEVLHLPNVTFEDAGEYTCLAGNSI
GISYHTATLTVLPG------------------------------------------------------------------
-----------------------------------H-SAPEKSPGPISPDYVEIAIYCAGVFLILCMVVIVVVCRMRTTA
-KKPD------FNGQPAVHKLTKQLPLRRQVT-----VSSDSSSSMNSNTPLVRITTRR-SSAHD-----LPIP-----E
YDLPEDPR--WEFS-RD---RLTLGKPLGEG--CFGQVV-MAEALGIDKDKPKEAA-TVAVKMLK---DDATEKDLSDLV
SEMEMMKMMGKHKNIINLLGACTQD---GPLYVIVEYASKGNLREYLRARRPPGMEY----------------SYDIARV
SDEQLTFKDLVSCTYQVARGMEYLASKKCIHRDLAARNVLVTESNVMKIADFGLARDVHNIDYYKKTTNGR---LPVKWM
APEALFDRVYTH----QSDVWSFGVLM----WEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPGNCTNELYMMMKDCWH
AISSQRPTFKQLVEDLDRILSLSTN-----------------------------------------------EEYLDLCA
P-TEQYSPSFPDTRS------------------SCSSGDDSVFSHDPLPDEPCLPKYQ--HINGNVKR------------
------------------------------
>Homo_sapiens_FGFR3
--------------------------------------------------------------------------------
MGAPACALALCVAVAIVA--------------------GASSESLGTEQ-------------------------------
-------RVVGRAAEVPGPEPG-------------------------QQEQLVFGSGDAVELSCPPPGGG-PMGPTVWVK
DGTGLVPSE------RVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVT------------------------
--------------------------------------------------------------------------------
--------------DAPSSGDDEDGEDE-------AEDTG-----------------------------------VDTGA
PYWTR-----PERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREF-RGEHRIGGIKLRHQQ--WSLVMESVVPSD
RGNYTCVVENKFGSIRQTYTLDVLER--SPHRPILQAGLPANQTAVLGSDVEFHCK-VYSDAQPHIQWLKHVEVNGSKVG
P-DGTPYVTVLKSWISESVEA---------------------------------DVR-LRLANVSERDGGEYLCRATNFI
GVAEKAFWLSVHGPRA----------------------------------------------------------------
------------------------------------AEEELVEADEAGSVYAGILSYGVGFFLFILVV-AAVTLCRLRSP
-PKKG------LGS-PTVHKISRFPLKR-QVS-------LESNASMSSNTPLVRIAR----LSS---GEGPTLANVS--E
LELPADPK--WELS-RA---RLTLGKPLGEG--CFGQVV-MAEAIGIDKDRAAKPV-TVAVKMLK---DDATDKDLSDLV
SEMEMMKMIGKHKNIINLLGACTQGG---PLYVLVEYAAKGNLREFLRARRPPGLDYS----------------FDTCKP
PEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGR---LPVKWM
APEALFDRVYTHQS----DVWSFGVLL----WEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPANCTHDLYMIMRECWH
AAPSQRPTFKQLVEDLDRVLTVTSTDE-----------------------------------------------YLDLSA
P-FEQYSPGGQDTPSSS----------------SS--GDDSVFAHDLLPPAP------PSSGGSRT--------------
------------------------------
>Macaca_mulatta_FGFR3
--------------------------------------------------------------------------------
MGAPACALALCVAVAIVA--------------------GASSESLGTEQ-------------------------------
-------RVVGRVAEVSGPEPS-------------------------QQEQLVFGSGDAVELSCPPPGGG-PMGPTVWVK
DGAGLVPSE------RVLVGPQRLQVLNASHEDSGAYSCRQRLTQLVLCHFSVRVT------------------------
--------------------------------------------------------------------------------
--------------DAPSSGDDEDGEDE-------AEDTG-----------------------------------VDTGA
PYWTR-----PERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGKEF-RGEHRIGGIKLRHQQ--WSLVMESVVPSD
RGNYTCVVENKFGSIRQTYTLDVLER--SPHRPILQAGLPANQTAVLGSDVEFHCK-VYSDAQPHIQWLKHVEVNGSKVG
P-DGTPYVTVLKSWISESVEA---------------------------------DVR-LRLANVSERDGGEYLCRATNFI
GVAEKAFWLSVHRPRA----------------------------------------------------------------
------------------------------------AEEELVEADEAGSVYAGILSYGVGFFLFILVV-AAVTLCRLRST
-PKKG------LGS-PTVHKISRFPLKR-QVS-------LESNASMSSNTPLVRIAR----LSS---GEGPTLANVS--E
LELPADPK--WELS-RA---RLTLGKPLGEG--CFGQVV-MAEAIGIDKDRAAKPV-TVAVKMLK---DDATDKDLSDLV
SEMEMMKMIGKHKNIINLLGACTQGG---PLYVLVEYAAKGNLREFLRARRPPGLDYS----------------FDTCKP
PEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGR---LPVKWM
APEALFDRVYTHQS----DVWSFGVLL----WEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPANCTHDLYMIMRECWH
AAPSQRPTFKQLVEDLDRVLTVTSTDE-----------------------------------------------YLDLSA
P-FEQYSPGGQDTPSSS----------------SS--GDDSVFAHDLLPPAP------PSSGGSRT--------------
------------------------------
>Mus_musculus_FGFR3
--------------------------------------------------------------------------------
MVVPACVLVFCVAV--VA--------------------GATSEPPGPEQ-------------------------------
-------RVVRRAAEVPGPEPS-------------------------QQEQVAFGSGDTVELSCHPPGGA-PTGPTVWAK
DGTGLVASH------RILVGPQRLQVLNASHEDAGVYSCQHRLTRRVLCHFSVRVT------------------------
--------------------------------------------------------------------------------
--------------DAPSSGDDEDGEDV-------AEDT---------------------------------------GA
PYWTR-----PERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGKEF-RGEHRIGGIKLRHQQ--WSLVMESVVPSD
RGNYTCVVENKFGSIRQTYTLDVLER--SPHRPILQAGLPANQTAILGSDVEFHCK-VYSDAQPHIQWLKHVEVNGSKVG
P-DGTPYVTVLKSWISENVEA---------------------------------DAR-LRLANVSERDGGEYLCRATNFI
GVAEKAFWLRVHGPQA----------------------------------------------------------------
------------------------------------AEEELMETDEAGSVYAGVLSYGVVFFLFILVV-AAVILCRLRSP
-PKKG------LGS-PTVHKVSRFPLKR-QVS-------LESNSSMNSNTPLVRIAR----LSS---GEGPVLANVS--E
LELPADPK--WELS-RT---RLTLGKPLGEG--CFGQVV-MAEAIGIDKDRTAKPV-TVAVKMLK---DDATDKDLSDLV
SEMEMMKMIGKHKNIINLLGACTQGG---PLYVLVEYAAKGNLREFLRARRPPGMDYS----------------FDACRL
PEEQLTCKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGR---LPVKWM
APEALFDRVYTHQS----DVWSFGVLL----WEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPASCTHDLYMIMRECWH
AVPSQRPTFKQLVEDLDRILTVTSTDE-----------------------------------------------YLDLSV
P-FEQYSPGGQDTPSSS----------------SS--GDDSVFTHDLLPPGP------PSNGGPRT--------------
------------------------------
>Rattus_norvegicus_FGFR3
--------------------------------------------------------------------------------
MVVPACVLVFCVAV--VA--------------------GVTSEPPGPEQ-------------------------------
-------RVGRRAAEVPGPEPS-------------------------QQEQVAFGSGDTVELSCHPPGGA-PTGPTLWAK
DGVGLVASH------RILVGPQRLQVLNATHEDAGVYSCQQRLTRRVLCHFSVRVT------------------------
--------------------------------------------------------------------------------
--------------DAPSSGDDEDGEDV-------AEDT---------------------------------------GA
PYWTR-----PERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGKEF-RGEHRIGGIKLRHQQ--WSLVMESVVPSD
RGNYTCVVENKFGSIRQTYTLDVLER--SPHRPILQAGLPANQTAVLGSDVEFHCK-VYSDAQPHIQWLKHVEVNGSKVG
P-DGTPYVTVLKTAGANTTDR---------------------------------ELEVLSLHNVTFEDAGEYTCLAGNSI
GFSHHSAWLVVLP-------------------------------------------------------------------
------------------------------------AEEELMEVDEAGSVYAGVLSYGVGFFLFILVV-AAVTLCRLRSP
-PKKG------LGS-PTVHKVSRFPLKR-QVS-------LESNSSMNSNTPLVRIAR----LSS---GEGPVLANVS--E
LELPADPK--WELS-RT---RLTLGKPLGEG--CFGQVV-MAEAIGIDKDRTAKPV-TVAVKMLK---DDATDKDLSDLV
SEMEMMKMIGKHKNIINLLGACTQGG---PLYVLVEYAAKGNLREFLRARRPPGMDYS----------------FDACRL
PEEQLTCKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGR---LPVKWM
APEALFDRVYTHQS----DVWSFGVLL----WEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPANCTHDLYMIMRECWH
AVPSQRPTFKQLVEDLDRILTVTSTDE-----------------------------------------------YLDLSV
P-FEQYSPGGQDTPSSS----------------SS--GDDSVFTHDLLPPGP------PSNGGPRT--------------
------------------------------
>Canis_familiaris_FGFR3
--------------------------------------------------------------------------------
-MVPPGGRVQVLSIPALG--------------------APALR-------------------------------------
--------SSISPTETPGPEPG-------------------------QQEPLVFGSGDTVELTCPSPIDS-PTGPSIWVK
DGVGLVPSD------RILVGPRRLQVLNASHEDAGTYSCRQRLTQRILCHFSVRVT------------------------
--------------------------------------------------------------------------------
--------------DAPSSGDDEDGEDE-------AEDTGSGG--------------------------------QRAGA
PYWTR-----PERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGKEF-RGEHRIGGIKLRHQQ--WSLVMESVVPSD
RGNYTCVVENKFGSIRQTYTLDVLER--SPHRPILQAGLPANQTAVLGSDVEFHCK-VYSDAQPHIQWLKHVEVNGSKVG
P-DGTPYVTVLKTAGANTTDK---------------------------------ELEVLSLRNVTFEDAGEYTCLAGNSI
GFSHHSAWLVVLP-------------------------------------------------------------------
------------------------------------AEEELVEAGEAGSVYAGVLSYGVGFLLFILVV-AAVTLCRLRTP
-PKKG------LGS-PTVHKVSRFPLKR-QVS-------LESNSSMNSNTPLVRIAR----LSS---GEGPALANVS--E
LELPADPK--WELS-RA---RLTLGKPLGEG--CFGQVV-MAEAIGIDKDRAAKPV-TVAVKMLK---DDATDKDLSDLV
SEMEMMKMIGRHKNIINLLGACTQGG---PLYVLVEYAAKGNLREYLRARRPPGMDYS----------------FDTCKL
PEEQLTCKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGR---LPVKWM
APEALFDRVYTHQS----DVWSFGVLL----WEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPANCTHDLYMIMRECWH
AVPSQRPTFKQLVEDLDRILTVTSTDE-----------------------------------------------YLDLSV
P-FEQYSPGGQDTPSSS----------------SS--GDDSVFAHDLLPPAP------PGGGGPRT--------------
------------------------------
>Bos_taurus_FGFR3
--------------------------------------------------------------------------------
MGAPARALAFCVAVAVMT--------------------GAALGSPGVEP-------------------------------
-------RVARRAAEVPGPEPS-------------------------PQE-RAFGSGDTVELSCRLPAGV-PTEPTVWVK
DGVGLAPSD------RVLVGPQRLQVLNASHEDAGAYSCRQRLSQRLLCLFSVRVT------------------------
--------------------------------------------------------------------------------
--------------DAPSSGDDEGGDDE-------AEDTAG--------------------------------------A
PYWTR-----PERMDKKLLAVPAANTVRFRCPAAGNPTPSITWLKNGKEF-RGEHRIGGIKLRQQQ--WSLVMESVVPSD
RGNYTCVVENKFGRIQQTYTLDVLER--SPHRPILQAGLPANQTAVLGSDVEFHCK-VYSDAQPHIQWLKHVEVNGSKVG
P-DGTPYVTVLKTAGANTTDK---------------------------------ELEVLSLRNVTFEDAGEYTCLAGNSI\r