>Homo sapiens_SHC1(ENSP_401303) MDLLPPKPKYNPLRNESLSSLEEGASGSTPPEELPSPSASSLGPILPPLPGDDSPTTLCS FFPRMSNLRLANPAGGRPGSKGEPGRAADDGEGIVGAAMPDSGPLPLLQDMNKLSGGGGR RTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALD FNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSS LNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDV ISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPL GGVVDMRLREGAAPGAARPTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCPAGR ELFDDPSYVNVQNLDKARQAVGGAGPPNPAINGSAPRDLFDMKPFEDALRVPPPPQSVSM AEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPE GVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVERKL >Gorilla gorilla_SHC1(ENSGGOP_13082) MDLLPPKPKYNPLRNESLSSLEEGASGSTPPEELPSPSASSLGPILPPLPGDDSPTTLCS FFPRMSNLRLANPAGGRPGSKGEPGRAADDGEGIVGAAMPDSGPLPLLQDMNKLSGGGGR RTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALD FNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSS LNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDV ISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPL GGVVDMRLREGAAPGAARPTAPSAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCPAGR ELFDDPSYVNVQNLDKARQAVGGAGPPNPAVNGSAPRDLFDMKPFEDALRVPPPPQSVSM AEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPE GVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVERKL >Macaca mulatta_SHC1(ENSMMUP_8657) MDLLPPKPKYNPLRNESLSSLEEGASGSTPPEELPSPSASSLGPILPPLPGDDSPTTLCS FFPRMSNLRLANPAGGRPGSKGEPGRAADDGEGIVGAAMPDSGPLPLLQDMNKLSGGGGR RTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALD FNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSS LNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDV ISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPL GGVVDMRLREGAAPGAARSTAPSAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCPAGR ELFDDPSYVNVQNLDKVRQAVGGAGLPNPAVNGSAPRDLFDMKPFEDALRVPPPPQSVSM AEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPE GVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVERKL >Mus musculus_SHC1(ENSMUSP_91940) MDLLPPKPKYNPLRNESLSSLEEGASGSTPPEELPSPSASSLGPILPPLPGDDSPTTLCS FFPRMSNLKLANPAGGRLGPKGEPGKAAEDGEGSAGAALRDSGLLPLLQDMNKLSGGGGR RTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALD FNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSS LNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDV ISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPL GGVVDMRLREGAARPTLPSAQMSSHLGATLPIGQHAAGDHEVRKQMLPPPPCPGRELFDD PSYVNIQNLDKARQAGGGAGPPNPSLNGSAPRDLFDMKPFEDALRVPPPPQSMSMAEQLQ GEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVVRT KDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVDRKV >Canis familiaris_SHC1(ENSCAFP_25262) MDLLPPKPKYNPLRNESLSSLEEGASGSTPPEELPSPSASSLGPILPPLPGDESPTTLCS FFPRMSNLKLANPAGEPGRASKDGEGTGGAAVLDSAPLPLLQDMNKLSGGGGRRTRVEGG QLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQV TREAISLVCEAVPGAKGATRRRKPCSRPLSAILGRSNLKFAGMPITLTVSTSSLNLMAAD CKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDVISTIGQA FELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPLGGVVDMR LREAAPLGAVRPTPHVVQTPSHLGATLPVGQPVGGDPEIRKQMPPPPPCPGKELFDDPSY VNVQNLDRARQAGGGAGPPNPAINGSVPRDLFDMKPFEDALRVPPPPQAVAMAEQLRGEP WFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVVRTKDH RFESVSHLISYHVDNHLPIISAGSELCLQQPVERKL >Myotis lucifugus_SHC1(ENSMLUP_2181) MDLLPPKPKYNPLRNESLSSLEEGASGSSPPEELPSPSASSLGPILPPQAGDDSPTTLCS FFPRMSNLKLANPAGARPGPKGEPGRVAEDGEGVAGAAVPDSGPLPLLQDMNKLSGGGGR RTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALD FNTRTQVTREAISLVCEAVPGAKGASRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSS LNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDV ISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPL GGVVDMRLREGAPQGPARPTLPSAQNPSHLGATLPVGQPAGGDPEVHKQMPPLPPCPAGR EIFDDPSYVNIQNLDKARQAGGGAGPPNLAVNGSAPRDLFDMKPFEDALRVPPPPQSVAM AEQLRGEPWFHGKLNRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPE GVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVERKL >Pteropus vampyrus_SHC1(ENSPVAP_762) MDLLPPKPKYNPLRNESLSSLEEGASGSTPPEELPSPSASSLGPILPPLPGDDSPTTLCS FFPRMSNLKLANPAGGRLGPKAEPGRAAEDGEGTTGAAVPDSGPLPLLQDMNKLSGGGGR RTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALD FNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSS LNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDV ISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPL GGVVDMRLREGAAPGATRPTPPSAQPPTQLGATLPVGQPVGGDPEVRKQMPPPPPCPAGR ELFDDPSYVNVQHLDKARHAGAGAGPPGLAVNGGAPRDLFDMKPFEDALRAPPPPHSVAM AEQLRGEPWFHGKLSRREAEALLQLDGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPE GVVRTKDHRFESVSHLISHHMDNHLPIISAGSELCLQQPVTRRP >Xenopus tropicalis_SHC1(ENSXETP_33635) MDLLPKTKYNHLRNESVSSVEEALAAGPLSPSVEIMVSLPSSASSSSLAPMLPLAELSSE SEESPTTLCSFFPKMANLKLSNPANLLNLRSFSSSMGGKESASPGEQGDTPNEGSSPESG RTFTVFSQDMNKLSCGRKSRVEGGQLAGDEWTRHGSFVNKPTRGWLHPDDKVMGPGVPYL VRYMGCVEVLQSMRALDFNTRTQVTREAISLVCDAVPGAKGAMRRRKTCGRSLNSILGKS NLKFAGMPITLTVSTSSLNLMASDCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVN QRACHILECPEGLAQDVISTIGQAFELRFKQYLKNPPKLVTPHDRMAGFDGSAWDEEEEE LPDHAYYNDFPGKEPPIGGVVDMRLRDGVAPAVPRQSPNHMGATLPVGQVSGAEQDSRKP QPTVQVPCSRPPNRPDLFDDPSYVNVQNLEKSRQPLRQQTARDPMGTNAVGTTTNFPVAP VEPFEDALPSAQAVVSMEDQLKRESWYHGKMNRKEAERLLKVNGDFLVRESTTTPGQYVL TGLQCGQPKHLLLVDPEGVVRTKDHRFESVSHLISYHMDNRLPIISAGSELCLQQPVERR Q >Danio rerio_SHC1(ENSDARP_89171) MEYVDMNRLGGASRRARVEGGQLGGDEWTRHGSFVNKPTRGWLHSDIVVSTSGVSYTVRY MGCVEVLQSMRALDFNTRTQVTREAISVVCEAVPGAKGAQRRRKPSSRCLSSILGKSNLQ FAGMTITLTVSTSSLNLMAIDCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRA CHILECSEGLAQEVISTIGQAFELRFKQYLKNPPKVVTPHDRMAPFDGSAWEEEEEDLAP PPEVPYYNNFPGKQPPPGGLVDMRTRPGHSTGPTLPYGQPSQNDIHKQPLPPLPVGVKDG GLFDDPSYVNVDKPRLPASAAANGNAHRDAFDMKPFDAALVVSGAVALPLAEQLQNEPWF HGPLSRRQAERLLTKDGDFLVRESGTTPGQYVLTGQQGGQPKHLLLVDPEGVVRTKDHRF ESVSHLISYHMDNRLPIISAGSEVCLQQPVDRKA >Takifugu rubripes_SHC1(ENSTRUP_15882) MELAPKTKYTHFRSESLSSTDETNSNPSSVPPSSPVSPLTPSPGMPSSLSSSSLTPILPP CSPHPAENSPTTLCSFFPRMGSLRLGVSATLLPSFKTASRPQNTRAPVESSGDDQSRARP SPPVHHPLPPLTDMNRLGGASRRARVEGGQLGGDEWTRHGSFVNKPTRGWLHSDGVVSTS GVSYTVRYMGCVEVLQSMRALDFSTRTQVTREAIAVVCEAVPGAKGAQRRRKPSSRCLSS ILGKSNLQFAGMTISLTVSTSSLNLLACDCKQIIANHHMQSISFASGGDPETAEYVAYVA KDPVNQRACHILECSEGLAQEVISTIGQAFELRFKQYLKNPPKLVTPHDRMAPFDGSAWE EEDEEPPPPPDVPYYNNFPGKQPPPGGLIDMRTRPGATLVRSMHISPTPIEETETIPYGQ PGQNDIHKQPLPPLPAGAKEGGLFDDPSYVNVDKPRPRVASNGNMHRDAFDMKPFDDALG VSGHSGTSSASAAPPLVQQLQCEAWFHGGLSRKEAERLLTRDGDFLVRESGTTPGQYVLT GQQGGQPKHLLLVDPEGVVRTKDHRFESVSHLISYHMDNRLPIISAGSEVCLKQPVERRA >Tetraodon nigroviridis_SHC1(ENSTNIP_21499) MELSPKTKYTHFRSESLSSTDETNSNLSSFPPSSPVTPLTPSPGVPSSHSSSSLTPILPP CSPRPAENSPTTLCSFFPRMGSIRLGVSATLLPSLKIASRPQNTQAPAESSGEDRSSSSS LQDMNRLGGASRRARVEGGQLGGDEWTRHGSFVNKPTRGWLHSDSVVSTTGVSYTVRYMG CVEVLQSMRALDFSTRTQVTREAISVVCEAVPGAKGAQRRRKPSSRCLSSILGKSNLQFA GMTISLTISTSSLNLLACDCKQIIANHHMQSISFASGGDPETAEYVAYVAKDPVNQRACH ILECSEGFAQEVISTIGQAFELRFKQYLKNPPKLVTPHDRMAPFDGSAWEEEDEETAPPP DVPYYNNFPGKQPPPGGLIDMRTRPGATLEHNKWKLSNANVNGSFFSVAPCLQPYGQPGQ NDIHKQPLPPLPAGAKEGGLFDDPSYVNVDKPRPPAASNGNMHRDAFDMKPFDDALGVSG HGGPSSASAAPPLVQQLQCEAWFHGGLSRKEAERLLTRDGDFLVRESGTTPGQYVLTGQQ GGQPKHLLLVDPEGVVRTKDHRFESVSHLISYHMDNRLPIISAGSEVCLKQPVERRA >Gasterosteus aculeatus_SHC1(ENSGACP_15982) MELVPKTKYTHFRSESLSSTDETNSDPSPLPPSSPATPLTPSPGLPPSLSSSSLAPILPP SSPRQAENSPTTLCSFFPRMGSLRLGVSATLLPGGDRSSSGSSPPLHRPTAPLTAPSPPP RPTLQDMNRLGGASRKARSEGAARKARVEGGQLGGDEWTRHGSFVNKPTRGWLHSDGVVT TAGVSYSVRYMGCVEVLQSMRALDFNTRTQVTREAISVVCEAVPGAKGAQRRRKPSSRCM TSILGKSNLQFAGMTISLTISTSSLNLLASDCKQIIANHHMQSISFASGGDPDTAEYVAY VAKDPVNQRACHILECSEGLAQEVISTIGQAFELRFKQYLKNPPKLVTPHDRMAPFDGSA WEEEEEDDNAAAAAAPPPDVPYYNNFPGKQPPPGGLVDMRSRPGATLPREAALMSNATFA QKGCRLAELLPYGQPGQNDIHKQPLPPLPVGAKEGGRELFDDPSYVNVDKPRHPVAANGN AHRDAFDMKPFDDALGVSGPGGASSSTAAPPPLVQQLQCEAWFHGSLSRREAERLLTRDG DFLVRESGTTAGQYVLTGQQGGQPKHLLLVDPEGVVRTKDHRFESVSHLISYHMDNSLPI VSAGSEVCLQQPVERRA >Oryzias latipes_SHC1(ENSORLP_12223) LVPKTKYTHFRSESLSSNDDTNSNPSSFPPSSPATPLTPSPGIPSSLSSSSLTPILPPTS PRPAENSPTTLCSFFPRMSSLRLGVTATLLPGLKASSRSQPSQLAVESSGDDRSNSSSSP PLHQPAPLLTAPSPPPRPPLQDMNRLGGASRRARVEGGQLGGDEWTRHGSFVNKPTRGWL HSDSVVSTTGVSYTVTYMGCVEVLQSMRALDFNTRTQVTREAIAVVCEAVPGAKGARRRK PSSRCLTSILGKSNLQFAGMPISLTISTSSLNLLASDCKQIIANHHMQSISFASGGDPDT AEYVAYVAKDPVNHRACHILECTEGLAQEVISTIGQAFELRFKQYLKTPPKLVTPHDRMA PFDGSAWDEEDDEIAPPPEVPYYNNFPGKQPPPGGIIDMRTRSGATLVRRHPLMHTTQHI RIQRGLQHRDDKPLYGQQGQNDIHKQPLPPLPGAKEGTRELFDDPSYVNVDKPRPPLAAN GNANRDAFDMRKLDGKRKKKLLEPNIIEEPLDDALGVSGTSAPPMVQQLQNEIWFHGSLT RREAERLLTRDGDFLVRESGTTPGQYVLTGQQGGQPKHLLLVDPEGVVRTKDHRFGSVSH LISYHLDNRLPIVSAGSEVYLQQPVERRA >Homo sapiens_SHC2(ENSP_264554) MTQGPGGRAPPAPPAPPEPEAPTTFCALLPRMPQWKFAAPGGFLGRGPAAARAAGASGGA DPQPEPAGPGGVPALAAAVLGACEPRCAAPCPLPALSRCRGAGSRGSRGGRGAAGSGDAA AAAEWIRKGSFIHKPAHGWLHPDARVLGPGVSYVVRYMGCIEVLRSMRSLDFNTRTQVTR EAINRLHEAVPGVRGSWKKKAPNKALASVLGKSNLRFAGMSISIHISTDGLSLSVPATRQ VIANHHMPSISFASGGDTDMTDYVAYVAKDPINQRACHILECCEGLAQSIISTVGQAFEL RFKQYLHSPPKVALPPERLAGPEESAWGDEEDSLEHNYYNSIPGKEPPLGGLVDSRLALT QPCALTALDQGPSPSLRDACSLPWDVGSTGTAPPGDGYVQADARGPPDHEEHLYVNTQGL DAPEPEDSPKKDLFDMRPFEDALKLHECSVAAGVTAAPLPLEDQWPSPPTRRAPVAPTEE QLRQEPWYHGRMSRRAAERMLRADGDFLVRDSVTNPGQYVLTGMHAGQPKHLLLVDPEGV VRTKDVLFESISHLIDHHLQNGQPIVAAESELHLRGVVSREP >Pan troglodytes_SHC2(ENSPTRP_17238) YMGCIEVLRSMRSLDFNTRTQVTREAINRLHEAVPGVRGSWKKKAPNKALASVLGKSNLR FAGMSISIHISTDGLSLSVPATRQVIANHHMPSISFASGGDTDMTDYVAYVAKDPINQRA CHILECCEGLAQSIISTVGQAFELRFKQYLHSPPKVTLPPERLAGPEESAWGDEEDSLEH NYYNSIPGKEPPLGGLVDSRLALTQPCALTALDQGPSPSLRDACSLPWDVGSTGTAPPGD GYVQADARGPPGHEEHLYVNTQGLDAPEPEDSPKKDLFDMRPFEDALKLHECSVAAGVTA APTVEDQWPSPPTRRSDGDFHVRESVTNPRLYVLTGMHAGQPKRLLVLDTEGV >Macaca mulatta_SHC2(ENSMMUP_32034) QYMGCIEVLRSMRSLDFNTRTQVTREAINRLHEAVPGVRGSWKKKAPNKALASVLGKSNL RFAGMSISIHISTDGLSLSVPATRQVIANHHMPSISFASGGDTDMTDYVAYVAKDPINQR ACHILECCEGLAQSVISTVGQAFELRFKQYLHSPPKVALPPESLEMNPQRQAGGWDSNSG LPAPSKSSSCGGLAPLGPACATRRRLSSQPTLDTSDEGPSASLRDARSLPWDVGSTGAAP PGDGYVQADARGPPDLEEHLYVNTQGLDAPEPEDSPKKDLFDMRPFEDALKLHECSVAAG MTAAPLPLEDQWPSPPTRRAPVAPTEEQLRQEPWYHGRMSRRAAERMLRADGDFLVRDSV TNPGQYVLTGMHAGQPKHLLLVDPEGVVRTKDVLFESISHLIDHHLQNGQPIVAAESELH LRGVVSREP >Mus musculus_SHC2(ENSMUSP_129491) MTQGPGGRAAPEPEAPTTFCALLPRMPQWKFAAPGSFLGRGPAATRVAGVAEAQPEPGVP ALAAVLGACEPRCAAPCPLPALGRCRGSGTRGARVTPDVADEWVRKGGFIHKPAHGWLHP DARVLGPGVSYIVRYMGCIEVLRSMRSLDFNTRTQVTREAINRLHEAVPGVRGSWKKKAP NKALASILGKSNLRFAGMSISVNISVDGLNLSVPATRQIIANHHMQSISFASGGDTDMTD YVAYVAKDPINQRACHILECCEGLAQSVISTVGQAFELRFKQYLHSPPKAVVPPERLTGL EELAWGDDDAAADHNYYNSIPGKEPPLGGLVDSRLAVTQPCALATLGGLGQGMTPVWRDA RGLPWDMGPSGAAPPGDGYVQADARGPHDYEEHLYVNTQGLDAVELEDTAEAPLQFEDSP KKDLFDMRPFEDALKLHACSVAAGITAASPPLEDQWPSPPTRRAPIAPTEEQLRQEPWYH GRMSRRAAEKLLRADGDFLVRDSVTNPGQYVLTGMHAGQPKHLLLVDPEGVVRTKDVLFE SISHLIDYHLKNGLPIVAAESELHLRGVVSREP >Canis familiaris_SHC2(ENSCAFP_29189) MTQGPGGRTPPAPPAPPEPEAPTTFCALLPRMPEWKFAAPAGFLGRGPAAARTAGGAGGA GGAGGAGGADPQPEEAAPGGVPALAAAVLGACEPRCAAPCPLPALSRCRAAGARGPRGAR GGAGPPDAAAAAEWIRKGSFIHKPAHGWLHPDARVLGPGVSYIVRYMGCIEVLRSMRSLD FNTRTQVTREAINRLHEAVPGVRGSWKKKAPNKALASILGKSNLRFAGMSIAVSISTDGL NLSVPATRQIIANHHMQSISFASGGDTDMTDYVAYVAKDPINQRACHILECCEGLAQSII STVGQAFELRFKQYLHSPPRVAVPPERLTRPEESAWGDEDEADHNYYNSIPGKEPPPGGL VDSRLALAQPGALGALGQGAAPARRDARSLPWDLGPSGAGPPGDGYVQADARGPRDYEDH LYVNTQGLDAPEPPQAEDSPKKDLFDMRPFEDALKLHECSAGAGTAVAPLPVEDQWPSPP TRRAPIAPTEEQLRQEPWYHGQMSRRAAEKLLRADGDFLVRDSVTNPGQYVLTGMHAGQP KHLLLVDPEGVVRTKDVLFESISHLIDYHLQNGQPIVAAESELHLRGVVKREP >Felis catus_SHC2(ENSFCAP_14316) YMGCIEVLRSMRSLDFNTRTQVTREAINRLHEAVPGIRGSWKKKAPNKALASILGKTNLR FAGMSIAVSISTDGLNLSVPATRQVIANHHMQSISFASGGDTDMTDYVAYVAKDPINQRA CHILECCEGLAQSIISTVGQAFELRFKQYLHSPPRVVLPPERLTRPEESAWGDEEETEHN YYNSIPGKEPPLGGLVDSRLALTQPCAVGALGQGVSPARRDTRSLPWDLGPSGNSPPGDG YVQADARGPRDYEDHLYVNTQGLDAPEPLQPEDSPKKDLFDMRPFEDALKLHECSAGAGA AVAPLPLEDQWPSPPTRRAPIAPTEEQLRQEPWYHGQMSRRAAEKLLRADGDFLVRDSVT NPGQYVLTGMHAGQPKHLLLVDPEGVVRTKDVLFESISHLIDYHLQNGQPIVAAESELHL RGVVKREP >Pteropus vampyrus_SHC2(ENSPVAP_47) YMGCIEVLRSMRSLDFNTRTQVTREAINRLHEAVPGVRGSWKKKAPNKALASILGKSNLR FAGMSIAVSISTDGLNLSVPATRQIIANHHMQSISFASGGDTDMTDYVAYVAKDPINQRA CHILECCEGLAQSVISTVGQAFELRFKQYLHSPPKAVAPLERLTGLEESAWGDEEDTDHN YYNSVPGKEPPLGGLVDSRLALTQPCALGGLGQGASPVRRDARGLQWEPGSSGTASAGDG YVQADARGPRDYEDHLYVNTQGLDAPESLPPEDSPKKDLFDMRPFEDALKLHECSVAAGT AAAPLPSEDQWPSPPTRRAPIAPTEEQLRQEPWYHGQMSRRAAEKLLRADGDFLVRDSVT NPGQYVLTGMHAGQPKHLLLVDPEGVVRTKDVLFESISHLIDYHLQNGQPIVAAESELHL RGVVKREP >Xenopus tropicalis_SHC2(ENSXETP_14356) MLAESRYDRFRNDSITSAEEQLALSAEAMSGQVAPSSPTGASALEPQYPEEQDVATTFCM MIPRMGQWKFSSPTAFLSRSPSGANKELTVDKSGTGGGLGSVFGACDPVCSTPCTLQVIN RLRGGGSGGARKSARTEAYKVQGEEWNRKGTFINKPAQGWLHPDDRLQGPGVSYIVRYMG CIEVLRSMRSLDFNTRTQVTREAINRLYETVPGVRGTWKKKAPNKSLASILGRSNLRFAG ISIAVNISTEGLNLSIPTSRQQVIANHHMQAISFASGGDADTTDYVAYVAKDPINQRACH ILECCEGLAQSVISTVGQAFELRFKQFLHSPPKVAAPPDRLLVGTEEPAWGGEEEQEHNY YNSIPGKEPPLGGLQDSRIREAGATGQLSTQININGQWSQVGSPARKPAVSHSCSQWDLE DQAQASEGFPLTNGRAFGVRDYEEHMYVNTQNLDGLVADKEPYMIPEDSPKKDLFDMRPF EDALKLHESSLSASQSLEDQWPSPPTRRAPVAPTEEQLRGEPWYQGKMSRREAEKLLQRD GDFLVRDSITNPGQYVLTGMHKGQPKHLLLVDPEGVVRTKDVLFESISHLISYHLHNQQP ILAAESELHLRQVVPRKV >Danio rerio_SHC2(ENSDARP_114455) MNRRTRVEGIWLGDNFTQKGSFINKPSQGWLHPDKKISSTGASYIVRYMGCIEVLKSMRS LDFSTRTQVTREAINRLCESVPGGKTAWKKKTTNKTLQSIMGKSNLRFAGMSIGVNISID GLSLLVPTTRQVIAHHPMQSISFASGGDSDTPDYVAYVAKDPVNQRACHILECCDGLAQN VISTIGQAFELQFKQYLHSPPKAIPAMDSHAEYPNILSRNIRTEESAWGEDEESSEHDYY NSIPGKEPPVGGVVDSRLRPPAGLLGHVHTHPQSKTSQMGSPAKRDANSLPATHLCYEVH WDTENNRSSSLTSDGYLRADGHPPGSRDYEEHLYVNTQNLDNLEASVVGRRPESPKKDIF DMRPFEDALRLHEASGVCVLEDKWPSPPRRRAPVAPTEDQLRREMWYHGRMSRRDAENLL GRDGDFLVRDSATNPGQYVLTGMQCGLPKHLLLVDPEGVVRTKDMLFESISHLINYHLTN KLPIVAAESELHLQQVVCRKI >Takifugu rubripes_SHC2(ENSTRUP_23380) MLLKPKYDRFRNESVTSSDDLMQSLAMSSKVVATPVVPSSAPSLPLPPLPPLDPGARSSL IPKMPQWKFSNSLLSRSPSNTGSGSNSSKDSGKAAAAPSHAPVPPSSSSPQRSSTMSSAG GPKGSFIHKPSQGWLHPDKKIAGPGASYIVRYMGCIEVLRSMRSLDFNTRTQVTREAINR LCEVVPGGRGAWRKKSTNKALQTVMGKSNLRFAGMSIAVNISIDGLSLLIPTTRQVIAHH PMQSISFASGGDTDTPDYVAYVAKDPVNQRACHILECSDGLAQGVISTIGQAFELQFKQY LHSPPKTLASVERSVRTEEPIWGEEESFSDHNYYNSIPGKEPPIGGVVDSRLRGVPQNCI MRGQDTSEFLRRNQASYPSGQLCYELHWDTETTSSSGLTSDGYLCADGQSAGGKDYEEHQ YVNTQNLDNLTSQGAEGPRAGRAPDSPLKDIFDMRPFEDALKLHEACAGAAGPTAAAAGG TQVLEDQWPSPPRRRAPVAPNEEQLRREPWYHSRMSRRDAERLLIRDGDFLVRESTTNPG QYVLTGMHCGLPKHLLLVDPEGVVRTKDMLFDSINHLIAYHLKNELPIVAAESELHLKQA VRRKP >Tetraodon nigroviridis_SHC2(ENSTNIP_18522) LRAAPPGMLLKPKYDRFRNESVTSSDDLMQSLAMSSKVVATPVVPSSAPSLPLPPLDDAT TTFCMLIPKMPQWKFSNSLLSRSPSNSSSGSSSSKDSGKAAAAPSQAPVAPTSSPQRNST MSSAGGPVTRVEGMWLAGEDFTQKGSFIHKPSQGWLHPDKKIAGPGASYIVRYMGCIEVL KSMRSLDFNTRTQVTREAINRLCEAVPGGRGAWRKKSMNKALQTVMGKSNLRFAGMSIAV NISIDGLSLLIPTTRQQVIAHHPMQSISFASGGDTDTPDYVAYVAKDPVNQRACHILECS DGLAQSVISTIGQAFELQFKQYLHSPPKSMASVERSARAEEPIWGEDEGFSDHDYYNSIP GKEPPIGGVVDSRLRGSGAPLGHVHSQPLGCTAAQVTLQTDDVNGMGSPARRDQASYPPD GQSAGSKDYEEHQYVNTQNLENLTSLGAEGPRGGRAPDSPKRDIFDMRPFEDALKLHPPR RRAPVAPNEEQLRRETWYHSRMSRRDAERLLIRDGDFLVRESTTNLGQYVLTGMHCGLPK HLLLVDPEGVVRTKDMLFDSISHLIAYHLKNELPIVAAESELHLKQAVRRKQ >Gasterosteus aculeatus_SHC2(ENSGACP_15271) MPQWKFSNSLLSRSPSNSSSSSGSSKDSGKAAAPQTSSSHSSSSHRHLAAVLTSCDPGCV TPCSLQAMRGQRVVAASSGSRSGMNRRTRVEGMWLGGEDFTQKGGFIHKPSQGWLHPDKK IAGPGASYVVRYMGCIEVLKSMRSLDFNTRTQVTREAINRLCDIVPGGKGAWRKKAQNKA LQSVMGKSNLRFAGMSIAVNISIDGLSLLIPTTRQVIAHHPMQSISFASGGDTDTPDYVA YVAKDPVNQRACHILECSDGLAQGVISTIGQAFELQFKQYLHSPPKTMASAERCARTEEA MWAEDEDFSQHDYYNSIPGKEPPVGGLVDSRLRPSGALLGHIHTQPQSKTAAQQTGSPGR REQASYPPGQLCYELHWDTETTGSSGLTSDGYLCADGQPPGSRDYEEHQYVNTQSLENLD VLAQGPNGHRGSRAPESPKKDLFDMRPFEDALKLHEACGGPAAGAGVRVLEDQWPSPPRR RAPVAPNEDQLRRETWYHSRMSRRDAEKLLVRDGDFLVRESTTNPGQYVLTGMHCGLPKH LLLVDPEGVVRTKDMLFESISHLIAYHLKNELPIVAAESELHLKQVVRRKQ >Oryzias latipes_SHC2(ENSORLP_21050) MPQWKFSNSLLSRSPSNSSSSSNSSKDSGKAAGAPSQASSTLAAVLNSCDPVCVTPCSLQ AIRGQRAVAAANSAAGAAEDFSHKGNFINKPSQGWLHPDKKIAGQGASYIVRYMGCIEVL KSMRSLDFNTRTQVTREAINRLCEAVPGGRGVWRKKAFNKALQTVMGKSNLRFAGMSIAV NISVDGLGLLIPTTRQVIAHHPMQSISFASGGDSDTPDYVAYVAKDPVNKRACHILECSD GLAPSVISTIGQAFELQFKQYLHSPPKSMGSLERSVRPEEPVWGDDEDPSEHDYYNSIPG KEPPIGGVVDSRLRPAGALLGHVHTQPPSKQAPQLHWDTDMTCSSGETPDGYLCADGQPT GIKDYEEHQYVNTQSLEHLDAQGADGQRGPNDSPKKDLFDMRPFEDALKLHKACGGAGSQ AGGGVVPILEDQWPSPPRRRAPVAPNEEQLRREPWYHSRMSRRDAEKLLVRDGDFLVRES TTNPGQYVLTGMHCGLPKHLLLVDPEGVVRTKDMLFESISHLISYHLKNGLPIVAAESEL HLKQVVRRKQ >Homo sapiens_SHC3(ENSP_364995) MLPRTKYNRFRNDSVTSVDDLLHSLSVSGGGGKVSAARATPAAAPYLVSGEALRKAPDDG PGSLGHLLHKVSHLKLSSSGLRGLSSAARERAGARLSGSCSAPSLAAPDGSAPSAPRAPA MSAARKGRPGDEPLPRPPRGAPHASDQVLGPGVTYVVKYLGCIEVLRSMRSLDFSTRTQI TREAISRVCEAVPGAKGAFKKRKPPSKMLSSILGKSNLQFAGMSISLTISTASLNLRTPD SKQIIANHHMRSISFASGGDPDTTDYVAYVAKDPVNRRACHILECCDGLAQDVIGSIGQA FELRFKQYLQCPTKIPALHDRMQSLDEPWTEEEGDGSDHPYYNSIPSKMPPPGGFLDTRL KPRPHAPDTAQFAGKEQTYYQGRHLGDTFGEDWQQTPLRQGSSDIYSTPEGKLHVAPTGE APTYVNTQQIPPQAWPAAVSSAESSPRKDLFDMKPFEDALKNQPLGPVLSKAASVECISP VSPRAPDAKMLEELQAETWYQGEMSRKEAEGLLEKDGDFLVRKSTTNPGSFVLTGMHNGQ AKHLLLVDPEGTIRTKDRVFDSISHLINHHLESSLPIVSAGSELCLQQPVERKQ >Gorilla gorilla_SHC3(ENSGGOP_12215) MLPRTKYNRFRNDSVTSVDDLLHSLSVSGGGGKVSAARATPAAAPYLVSGKALRKAPDDG PGSLGHLLHKVSHLKLSSSGLRGLSSAARERAGARLSGSCSAPSLAAPDGSAPSAPRAPA MSAARKGRPGDEPLPRPPRGAPHASDQVLGPGVTYVVKYLGCIEVLRSMRSLDFSTRTQI TREAISRVCEAVPGAKGAFKKRKPPSKMLSSILGKSNLQFAGMSISLTISTASLNLRTPD SKQIIANHHMRSISFASGGDPDTTDYVAYVAKDPVNRRACHILECCDGLAQDVIGSIGQA FELRFKQYLQCPTKIPALHDRMQSLDEPWTEEEGDGSDHPYYNSIPSKMPPPGGFLDTRL KPRPHAPDTAQFAGKEQTYYQGRHLGDTFGEDWQQTPLRQGSSDIYSTPEGKLHVAPTGE APTYVNTQQIPPQAWPAAVSSAESSPRKDLFDMKPFEDALKNQPLGPMLSKAASVECISP VSPTAPDAKMLEELQAKTWYQGEMSRKEAEGLLEKDGDFLVRKSTTNPGSFVLTGMHNGQ AKHLLLVDPEGTIRTKDRVFDSISHLINHHLESSLPIVSAGSELCLQQPVERKQ >Macaca mulatta_SHC3(ENSMMUP_26786) MLPRTKYNRFRNDSVTSVDDLLHSLSVSGGGGKVSAARATPAAAPYLVSGEALRKAPDDG PGSLGHLLHKVSHLKLSSSGLRGLSSAARERAGARLSGSCSAPSLAAPDGSAPPAPRAPA MSTARKGRPGDEPLPRPPRGAPHASDQVLGPGVTYVVKYLGCIEVLRSMRSLDFSTRTQI TREAISRVCEAVPGAKGAFKKRKPPSKMLSSILGKSNLQFAGMSISLTISTASLNLRTPD SKQIIANHHMRSISFASGGDPDTTDYVAYVAKDPVNRRACHILECCDGLAQDVIGSIGQA FELRFKQYLQCPTKIPALHDRMQSLDEPWTEEEGEGSDHPYYNSIPSKMPPPGGFLDARL KPRPHAPDTAQFAGKEQTYYQGRHLGDTFGEDWQQAPFRQNERQGSLDIYSMPEGKLHVA PTGEAPTYVNTQQIPPQAWPTVVSSAESSPRKDLFDMKPFEDALKNQPLGPVLSKAASVE CISPVSPRAPDAKMLEDLQAETWYQGEMSRKEAEGLLEKDGDFLVRKSTTNPGSFVLTGM HNGQAKHLLLVDPEGTIRTKDRVFDSISHLINHHLESSLPIVSAGSELCLQQPVERKQ >Mus musculus_SHC3(ENSMUSP_21898) MSATRKSRAGDEPLPRPPRGAPHTSDQVLGPGVTYVVKYLGCIEVLRSMRSLDFSTRTQV TREAISRVCEAVPGAKGALKKRKPPSKMLSSILGKSNLQFAGMSISLTISTASLNLRTPD SKQIIANHHMRSISFASGGDPDTTDYVAYVAKDPVNRRACHILECCDGLAQDVIGSIGQA FELRFKQYLQCPSKVPALQDRMQSLDEPWTEEEGDGPDHPYYNSVPTKMPPPGGFLDARL KGRPHAPEAAQFAGKEQTYYQGRHLGDTFGEDWQRAPTRQGSLDIYSTAEGKTHMVPVGE TPTYVNTQPVPPQVWPAATSSTESSPRKDLFDMKPFEDALRNQPLGPMLSKAASVECISP VTPRAPDARMLEELNAEPWYQGEMSRKEAEALLREDGDFLVRKSTTNPGSFVLTGMHNGQ AKHLLLVDPEGTIRTKDRVFDSISHLINYHLESSLPIVSAGSELCLQQPVERKP >Rattus norvegicus_SHC3(ENSRNOP_19442) MLPRTKYNRFRNDSVTSVDDLLHSLSVSGSGGKVSAEPAASPYLVSGEALRKAPDDGPGS LGHLLHKVSHLKLSSSGLRGLSSAARERAGARLSGSCSAPSLAAPDGGSATPGSRAPAAS MSATRKSRASDEPLPRPPRGAPHASDQVLGSGVTYVVKYLGCIEVLRSMRSLDFSTRTQV TREAISRVCEAVPGAKGAFKKRKPPSKMLSSILGKSNLQFAGMSISLTISTASLNLRTPD SKQIIANHHMRSISFASGGDPDTTDYVAYVAKDPVNRRACHILECCDGLAQDVIGSIGQA FELRFKQYLQCPSKIPALQDRMQSLDEPWTEEEGDGPDHPYYNSVPNKMPPPGGFLDARL KARPHAPDAAQFSGKEQTYYQGRHLGDAFGEDWQRAPTRQGSLDIYSTPEGKAHMVPVGE TPTYVNTQPVPPQVWPAATSSTESSPRKDLFDMKPFEDALRNQPLGPVLSKAASVECISP VTPRAPDAKMLEELNAEPWYQGEMSRKEAEALLQEDGDFLVRKSTTNPGSFVLTGMHNGQ AKHLLLVDPEGTVRTKDRVFDSISHLITYHLESSLPIVSAGSELCLRQPVERKP >Canis familiaris_SHC3(ENSCAFP_3204) MRSLDFSTRTQITREAISRVCEAVPGTKGAFRKRKPPSKMLSSILGKSNLQFAGMSISLT ISTASLNLRTPDSKQIIANHHMQSISFASGGDPDTTDYVAYVAKDPVNRRACHILECCDG LAQDVIGSIGQAFELRFKQYLQCPSKVPAFHDRMQSLDEPWTEEEGDGSDHPYYNSIPSK TPPPGGFVDVRLHARPHAPDTAQFAGKEQTYYQGRHLGDPFGEDWQQTPVRQGSLDIYST PEARVPAAPGEAPTYVNAQHIPVQATPASGSSTESSPLKDLFDMKPFEDALRNQSLGPVL SKAASVECISPVTPRAPDAKMLEELEGEPWYQGEMSRKEAEGLLKNDGDFLVRKSATNPG SFVLTGMHNGQAKHLLLVDPEGTIRTKDRVFDSISHLINHHLENSLPIVSAGSELCLQQP VEKTL >Myotis lucifugus_SHC3(ENSMLUP_6051) MLPRTKYNHFKKDSVTSVDDLLHLSVSGGSKVSAARAAPAAAAPYLVSGDALRRAPDDGS GSRGHLLHKVSHLKLASSGLRGLSAARERAGARLSGSCSAPSLAAPDGSAPPGPRAPAMR AARKGRPGEEPPPSAPPASDQVLGAGVTYVVKYLGCIEVLRSMRSLDFSTRTQITREAIS RVCEAVPGAKGAFRKRKPPSKMLSSILGKSNLQFAGMSISLTISTASLNLRTSDSKQIIA NHHMQSISFASGGDPDTTDYVAYVAKDPVNRRACHILECCDGLAQDVIGAIGQAFELRFK QYLRCPSKVPALHDRMQSLDEPWTEEEGAGSDHPYYNSIPNKAPPAGGVDARLKARPHGP DSAPFSGKEQTYYQGRHVGEPFGEDWQQTPARQGSLDTSSMPGGTAPAAPTGEAPTYMNT PHFPPQAGPAAGSSAESSPRKDLFDMKPFEDALKNQPVGPVLSKAASVECISPVSPRAPD AKMLEELKAELWYQGQMSRKEAEGLLKRDGDFLVRKSTTNPGSFVLTGMHDGQAKHLLLV DPEGTIRTRDRIFDSISHLINHHLANRLPIVSAGSELCLQQPVERNP >Pteropus vampyrus_SHC3(ENSPVAP_3507) RKADDGPGSLGQLLHKVSHKLSSSGLRGLSAARERAGARLSGSCSAPSLAAPDGSAPPGP RAPAMRASRKGRPGDEPPPRASPASDQVLGAGVTYVVKYLGCIEVLRSMRSLDFSTRTQI TREAISRVCEAVPGAKGAFRKRKPPSKMLSSILGKSNLQFAGMSISLTISTASLNLRTPD SKQIIANHHMQSISFASGGDPDTTDYVAYVAKDPVNRRACHILECCDGLAQDVISSIGQA FELRFKQYLQCPSKISAFHDRMQSLDEPWTEEEGDGSDHPYYNSIPSKTPPPGGFVDARL KVRSHVPDTAQFAGKEQTYYQGRHLGELFGEDWQQTPIRQGSVDIYSMPEGKAHVAPTGE APTYVNTQHFPLQAGPSASSSAESSPRKDLFDMKPFEDALKNQSIGPVLSKAASVECISP ISPRAPDAKMLEELKAEPWYQGEMSRKEAEGLLKRDGDFLVRKSTTNLGSFVLTGMHDGQ AKHLLLVDPEGTIRTKDRIFDSISHLINHHLENSLPIVSAGSELCLQQPVERNL >Gallus gallus_SHC3(ENSGALP_17365) MLQRTKYNRFRNDSVTSVNDLIHNLSMNSKVSAAATASAASSYLVTPEVLRKDQEDGPTT LCTLIHKVSHLKFSNAGSLLGIKNLSSAVKELAVSKLQGSSSASSSAAEASDNACNLVSA TSCSQQDISKMSVGKKARSEEMHPGDEDWNQRSSIVDKPSQGWLHLSEKILGPGVTYIVK YLGCIEVLRSMRSLDFNTRTQITREAISRVCEAVPGAKGAFKKRKPPSKVLSSILGKSNL QFAGISIMLNISTTSLNLMTPDMKQIIANHHMQSISFASGGDPDTTDYVAYVAKDPVNRR ACHILECCNGLAQDVISTIGQAFELRFKQYLQCPSKMPTFHDRMQSFDEPLMEEESAAAE HPYYNNIPNKMPPPGGFINARLKAKIPTAADTAQFAAGVRREKIYYQNRHLGDKFNEDWH EETVKQGPLDIYSMPEGKSEATARAEMPMYVNAQHINMETLLALQADAESDISGNTDSTK ESSPEKDLFDMKLEPFEDALKNQTSEPVLSKLTSVECTSPLLCRAADWTRTEDLSIEPWY QGEMSRKEAEQLLKKCGDFLVRKSTTNPGSYVLTGMQNGQAKHLLLVDPEGTVRTKDRVF DSISHLINHHLENNLPIVSSGSKLCLQQPAERKH >Xenopus tropicalis_SHC3(ENSXETP_16941) MLQRTKYNRFKNESVTPVDDLLHNLSMNSKVTTVAGNPASPPCSAPPDVLQKDQENGPTT LCTFIHKVSNLKLSSSGSLLGIKNLSSAVKELTGSKLQGSSPALSIAAGATENTCNLVST PCSQQDLNKMSTGKKTPEEMHQGGEDWNQSSSFVNKPSRGWLHSNEKILGPGVTYIVKYL GCIEVLRSMRSLDFNTRTQITREAFNRVCEAVPGTKGVFKKRKPANKNLSSILGKSNLQF AGMSITLNISTTSLNMMTPDTKQIIANHHMQSISFASGGDPDATDYVAYVAKDPVNRRAC HILECCDGLAQDVISTIGQAFELRFKQYLQCPSKIPVFPDRMQSLDDPLWQEEDGMTTEH QYYNSIPNKMPPPGGIIDERLKTHISNQGDNTQSVPLEQSYYQGRHLVEKSCENFQQTVK RQASLDIYSLPEGKSSINQTSNAPTYVNTQHINKKTLGAIQKSADSILCKSVDSSRDISP RKDIFDMKPFEDALKNQPVLSKDASVDCSSPLLSRAAILTINEELRSEPWYVGEMCRREA EKLLKRDGDFLVRKSINNPGSYVLTGMHNGLAKHLLLVDPEGTVRTKDRVFDSIGHLINH HLENNLPIVSSGSELCLKQPMEGKP >Danio rerio_SHC3(ENSDARP_139836) MLHRAKYNRFRNESVTSVDELLHGLSMNAKVSAVPPSPPVGDPPYAPPADPDPAEESGTL CTLINKVSNLKFTNSSGLLGIKGLPSAVKDLAVSKLQGGAAAGASSSPASSTLAAASPLE PGSTSSGKKGRMEESQPSGEGWSLGGTGAAGCGGLVNKPSHGWLHSSEKISGPGVTYVVK YLGCIEVLRSMRSLDFTTRSQITRGLFNILLQMTTGSDGEVINGDETPSKLLSSILGKSN LQFAGMSINLNISTSSLNLMTPDSKQIIANHHMQSISFASGGDPDTTDYVAYVAKDPVNR RACHILECSDGLAQDVISTIGQAFDLRFQLYLQCPSSKPSSIHDRVMSTDEPPWTEEGDE TADHHYYNSIPGKMPPPGGFIDARLTNQSQDSSQGAGVDQTYYQGRPMFIQQEKTFNCMF NNKRSCDIYSLPEVKAQPPKAGEVPTYVNTQHIDTQVLAALQAETETNADSSTTGAPKDS PRKDLFDMKPFEDAIMTQTPAASELHKAASVDNSSPLLMRAAALRAHEELEDQRWYHGEM SRRQAEKLLLHDGDFLVRKSTTNPGSYVLTGMHNGLAKHLLLVDPEGTVRTKDHIFESIS HLIGHHRDNNLPIVSAGSELCLKQPVDRKQ >Takifugu rubripes_SHC3(ENSTRUP_26154) MLHRTKYNRFRNESVTSVDELLHGLPMNPKVSASPETSYTPPTEVQSFSTATASSTPACL GSDHLEDGGTTLCTLINKVSGLKFSNSGSLLGIKGLPSAVKDLAVSKLQAASSSGGSACG SHSVPCSQLEPAVGMSKKSRLDELQLGKPSRGWVHSSDKISGPGVTYIVKYLGCIEVLRS MRSLDFTTRSQITREAISLVCEAVPGTKGALRKRKPPSKTLSSILGKSNLQFAGMSINLN ISTSSLNLMTPDGKQIIANHHMQSISFASGGDPDTTDYVAYVAKDPVNRRACHILECSDG LAQDVIGTIGQAFDLRFQQYLQCPSSKISSPHDRVLNMEELTWTEEEEESTEHPYYNNIP GKMPPPGGIVDTRLTNQNAAQDGCQMGPGSIDQTYYQGRHCGENWGDDRKPIFIQQGSFD IISLPESKGQAQRAEMPAYVNTQQIDAQVLAALQAEGENVTKGLASAPAKESPQKDLFDM KPFEDAIQSEGPEHSQAAGLHKAASVDNASPLLVRSLAFRAQEELEGQTWYHGIMSRREA EKLLQDDGDFLVRKSTTNPGSYVLTGMHNGLAKHLLLVDPEGTVRTKDHVFDSILHLIGH HRDNNLPILSAGSELFLLQPVGRKQ >Tetraodon nigroviridis_SHC3(ENSTNIP_21940) MLHRTKYNRFRNESVTSVDELLHGLPMNPKVSASPETSYTPTAEVQSSSTTTASSTPASL GSNHLEDGGTTLCTLINKVSGLKFSNSGSLLGIKGLPSAVKDLAVSKLQVGGGSGSCGSG SPSPCGRLRVRPPRSPLLTAGAGRRHEQESVSKPSRGWLHSSDKISGPGVTYIVKYLGCI EVLRSMRSLDFTTRSQITREAISLVCEALPGTKGALRKRKPPSKTLSSILGKSNLQFAGM SINLNISTNSLNLMTPDGKQIIANHHMQSISFASGGDPDTTDYVAYVAKDPVNRRACHIL ECSDGLAQDVISTIGQAFDLRFQQYLQCPSGKISSPHDRVLNMEELTWTEEEEESAEHPY YNNIPGKMPPPGGIIDTRLTSQNTAQDGCQMGPGSIDQTYYQGRHCAENWGDDRKPVFIQ QGSFDVISLPESKVQAQKVEMPAYVNTQQIDAQVLAALQAEAKESPQKDLFDMTEPFEDA IHSQGPEPSQAAALSKAASVDNASPLLVRSLAFRAQEELEGQEWYHGIMSRREAEKLLRD DGDFLVRKSTTNPGSYVLTGLHNGLAKHLLLVDPEGTVRTKDHVFDSILHLIGHHRDNNL PILSAGSELFLLQPVGRKQ >Gasterosteus aculeatus_SHC3(ENSGACP_21815) MLHRTKYNRFRNESVTSVDELLHGLSMNPKVSATPQSAAETSYTPPTEVQPSAAAACSIS TGHGSDHLEDGGTTLCTLINKVSGLKFSNSGSLLGIKGLPSAVKDLAASKLQGGGGLGSG GGGGGGGGVPAAATSGDWNPGGGGGGLVIKPSRGWLHSSEKISGPGVTYVVKYLGCIEVL CSMRSLDFTTRSQITREAISLVCEAVPGTKGALRKRKPPSKALSSILGKSNLQFAGMSIN LNISTSSLNLMTPDCKQIIANHHMQSISFASGGDPDTTDFVAYVAKDPVNRRACHILECS DGLAQDVIRTIGQAFDLRFQQYLQCPSGKLSSTHDRVLNMEELPWTEEEEESAEHPYYNN IPGKMPPPGGFIDTRLTTQNAAADGCGVQLLDQTYYQGRHCGENWGDERKVIFIQQGSFD ISGLPESKGQAPKTGEMPAYVNTQQIDAQVLAALQAEAEHCPQKDLFDMKPFEDAIQSQS HPPSQPQVAAIHKTASVDNCSPLLARSVAFRAQEELQGQMWYHGQMSRRDAEKLLKEDGD FLVRTSTTNPGSDVLTGMHNGLAKHLLLVDPEGTVRARRA >Oryzias latipes_SHC3(ENSORLP_7238) MLHRTKYNRFRNESVTSVDELLHGLSMNPKVSATPHSAAETPYTPPTEVQSSSGTPLSNA PTSHGSDHLEDGGTTLCTLINKVSNLKFSNSGSLLGIKGLPSAVKDLAVSKLQGGGGSGS SSGSSPSAATAAAASVPCSQQEPALSMSKKSRLDELLPSGEDWNPGGGGGLVSKPSRGWL HSNEKISGPGVTYIVKYLGCIEVLRSMRSLDFTTRSQITREAISLVCEAVPGTKGALRKK KPPSKALSNILGKSNLQFAGMSINLNISTSSLNLMTPDCKQIIANHHMQSISFASGGDPD TTDFVAYVAKDPVNRRACHILECADGLAQDVISTIGQAFDLRFQQYLQCPSNKPSSTHDR ILNMEELPWTEEEEESTDHPYYNNIPGKMPPPGGFIDTRLTNQNAASEGSQVCGKMATGS VDQMYYQGRHCEGWAEERRPIIIQQGLGSFDIVGFPESKSQAAKTGEMPTYVNTQQIDAQ VLAALQAEAENVMKGMAATTKDSPQMDLFDMKPFEDAIQSHPPSQGQTQTPVSNLHKAAS VDNSSPLLVRSLAFRAQEELEDQTWYHGKTSRRDAEKLLKQDGDFLVRKSTTNPGSYVLT GMHSGLAKHLLLVDPEGTVRTKDHIFDSISHLIGHHRDNNLPIVSAGSELCLLQPVARKQ >Homo sapiens_SHC4(ENSP_329668) MRERGQDSLAGLVLYVGLFGHPGMLHRAKYSRFRNESITSLDEGSSGGSVGNKGSPQPPH PALAPHLPTEDATLPSQESPTPLCTLIPRMASMKLANPATLLSLKNFCLGTKEVPRLKLQ ESRDPGSSGPSSPETSLSRSGTAPPPQQDLVGHRATALTPDSCPLPGPGEPTLRSRQDRH FLQHLLGMGMNYCVRYMGCVEVLQSMRSLDFGMRTQVTREAISRLCEAVPGANGAIKKRK PPVKFLSTVLGKSNLQFSGMNIKLTISTCSLTLMNLDNQQIIANHHMQSISFASGGDPDT TDYVAYVAKDPVNQRACHILECHNGMAQDVISTIGQAFELRFKQYLKNPSLNTSCESEEV HIDSHAEEREDHEYYNEIPGKQPPVGGVSDMRIKVQATEQMAYCPIQCEKLCYLPGNSKC SSVYENCLEQSRAIGNVHPRGVQSQRDTSLLKHTCRVDLFDDPCYINTQALQSTPGSAGN QRSAQPLGSPWHCGKAPETVQPGATAQPASSHSLPHIKQQLWSEECYHGKLSRKAAESLL VKDGDFLVRESATSPGQYVLSGLQGGQAKHLLLVDPEGKVRTKDHVFDNVGHLIRYHMDN SLPIISSGSEVSLKQPVRKDNNPALLHSNK >Gorilla gorilla_SHC4(ENSGGOP_10158) MRERGQDSLAGLVLYVGLFGHPGMLHRAKYSRFRNESITSLDEGSSGGSVGNKGSPQPPH PALAPHLPTEDATLPSQESPTPLCTLIPRMASMKLANPATLLSLKNFCLGTKEVPRLKLQ ESRDPGSSGPSSPETSLSRSGTAPPPQQDFVGHRATALTPDSCALPGPGEPTLRSRQDRH FLQHLLGMGMNYCVRYMGCIEVLQSMRSLDFGMRTQVTREAISRLCEAVPGANGAIKKRK PPVKFLSTVLGKSNLQFSGMNIKLTISTCSLTLMNLDNQQIIANHHMQSISFASGGDPDT TDYVAYVAKDPVNQRACHILECHNGMAQDVISTIGQAFELRFKQYLKNPSLNTSCESEEV HIDSHAEEREDHEYYNEIPGKQPPVGGVSDMRIKVQATEQMAYCPIQCEKLCYLPGNSKC SSVYENCLEQSRAIGNVHPRGVQSQRDTSLLKHTCRVDLFDDPCYINTQALQSTPGSAGN QSSVQPLGSPWHCGKAPETVQPGATAQPASSHSLPHIKQQLWSEECYHGKLSRKAAESLL VKDGDFLVRESATSPGQYVLSGLQGGQAKHLLLVDPEGKVRTKDHVFDNVGHLIRYHMDN SLPIISSGSEVSLKQPVRKDNNPALLHSNK >Macaca mulatta_SHC4(ENSMMUP_12873) MRERSQDSLAGLVLYVGLFGHPGMLHRAKYSRFRNESITSLDEGSSGGSVGNKGSPQPPH PALAPHLPAEDAALPSQESPTPLCTLIPRMASMKLANPATLLSLKNFCLGTKEVPRLKLQ ESRDPGSSSPSSPETSLSRSGTAPPPQPDLVSHRATALTPDSCPLPGPGEPPLRSRQDRH FLQHLLGMGMNYCVRYMGCIEVLQSMRSLDFGMRTQVTREAISRLCEAVPGANGAIKKRK PPVKFLSTVLGKSNLQFSGMNIKLTISTCSLTLMNLDNQQIIANHHMQSISFASGGDPDT TDYVAYVAKDPVNQRACHILECHNGMAQDVINTIGQAFELRFKQYLKNPSLDTSCESEEV RIDSHAEESEDHEYYNEIPGKQPPAGGVSDMRIKVQATEQMAYCPIRCEKLCYLPGNSKC SSVYENCLEQSRAIGNVHPRGVQSQRDTSLLKHTCRVDLFDDPCYINTQALQSTLGSAGN QSSAQPLGSPWHCGKAPETVQPGATAQPASSHSLPHIKQQLWSEECYHGKLSRKAAESLL VKDGDFLVRESATSPGQYVLSGLQGGQAKHLLLVDPEGKVRTKDHVFDNVGHLIRYHMDN SLPIISSGSEVSLKQPVRKDNNPALLHSNK >Canis familiaris_SHC4(ENSCAFP_21819) MRRRGRDSLAGLVLCVGLVGHPGMLHRAKYSRFRNESVTSLDESGPGGGAGGDKGSPQPP YPALAPHLPPEDATLAAQESPTPLCTLIPRMASVKLANPATLLSLKNFCLGTKEVPRLKL QESQDPAPSSPAPPEAGLTRAGPAPLPQQPGPVGHRATVLTPEACPLPGAGQPTPGSRQD RHFLQHLLGMGMNYYVRYMGCIEVLQSMRSLDFGMRTQVTREAISRLCEAVSGANGAVKK RKPPVKFLSTVLGKSNLQFSGMNIKLTISTCSLTLMNIDNQQIIANHHMQSISFASGGDP DTTDYVAYVAKDPVNQRACHILECRSGMAQDVISTIGQAFELRFKQYLKNPSLNTSCESE GVPIDDHAEEREDHEYYNEIPGKQPPAGGVSDVRIKVQATEQMAYCPIRCEKLCYLPGNS KCSSVYENCLEQSRAIGNAQERGVQSHRDASLMKHACRVDFFNDPCYINTQAFQSTLGSA PNQSSAHVLGSPWHREKAPETVQPGATAQPASSHSLPHVKQQLRSEDCYHGKLSRKAAES LLVKDGDFLVRESATSPGQYVLSGLQGGQAKHLLLVDPEGKVRTKDHVFDNVGHLIRYHM DNSLPIISSGSEVSLKQPVRKDNNPGLLHSNK >Felis catus_SHC4(ENSFCAP_20059) MRKRGQDSLAGLVLYVGLFGHPGMLHRAKYSRFRNESITSLDESSPGGSVGSKGSAPPPY PTLAPHLPAEDATLASQESPTPLCTLIPRMASVKLANPATLLSLKNFCLGTKEVPRLKLQ ESQDPAPSSPASPETSPNRAGSAPLPQPDLLGHRAAALTPDACPLPGPGEPTPGSRQDRH FLQHLLGMGMNYYVRYMGCIEVLQSMRSLDFGMRTQVTREAISRLCEAVSGANGAVKKRK PPVKFLSTVLGKSNLQFSGMNIKLTISTCSLTLMNIDNQQIIANHHMQSISFASGGDPDT TDYVAYVAKDPVNQRACHILECRSGMAQDVISTIGQAFELRFKQYLKNPSLNTSCESEEV PLDGPAVEREDHEYYNEIPGKQPPAGGVSDVRIKDQATEQMAYCPIRCEKLCYLPGNSKC SSVYENCLEQSRAIGNAQERGGQCQRDAALMKHTCRVDFLNDPCYINTQGLQSTLGSSPN QSSAHSLGSPWHRQKAPETVQPGATAQPASSHSLPHIKQQLRNEDCYHGKLSRKAAESLL VKDGDFLVRESATSPGQYVLSGLQGGQAKHLLLVDPEGKVRTKDHVFDNVGHLIRYHMDN SLPIISSGSEVSLKQPVRKDNNPGLLHSNK >Myotis lucifugus_SHC4(ENSMLUP_11751) MRERSPDGLAGLALHVGLFGHPGMLHRAKYSRFRNESVTSLDEGSPGGSVGNKGSPQPPY PALAPHLLAEDAPSPSQESPTPLCTLIPRMASVKLANPATLLSLKNFCLGTKEVPRLKLQ ESQDPAPSSPASPENSLNRSGSAPPQQRDVVGRRASALTPDACPLPGPGDPTPGSRQDRH FLQHLLGMGMNYCVKYMGCIEVLQSMRSLDFGMRTQVTREAISRLCEAVPGANGATKKRK PPVKFLSTVLGKSNLQFSGMNIKLTISTCSLTLMNLDNHQIIANHHMQSISFASGGDPDT TDYVAYVAKDPVNQRACHILECRNGMAQDVITTIGQAFELRFKQYLKNPSLNTSCESEEV HIDGHADERDDHEYYNEIPGKQPPMGGVSDVRVRVQATEQMAYCPIRCEKLCYLPGNSDC SSVYENCLEQSRAIGNAHERAVPSQRDTALMKHTCRVDLFDDPCYINTQALHSALGSTRN PGSAQLLGSLWHREKAPETVQPGATAQPASSRSLPYIQQQLRSEDCYHGKLSRKAAENLL VKDGDFLVRESATSPGQYVLSGLQGGQKHLLLVDPEGKVRTKDHIFDNVGHLIRYHMDNS LPIISSGSEVSLKQPVRRDNIPGLLHLNK >Pteropus vampyrus_SHC4(ENSPVAP_11141) MRERSQDSLAGLVLYVGLFGHPGMLHRAKYSRFRNESITSLDEGSPGGSVGNKSSPQPPY PALAPHLPAEDATLASQESPTPLCTLIPRMASVKLANPATLLSLKNFCLGTKEVPRLKLQ ESQDLAPSNRASPEPSQNRAGSAPPSQQDVVGHRPTALTPDVCPLPGPGEPTPGNRQDRN FLQHLLGMGMNYYVRYMGCIEVLQSMRSLDFGMRTQVTREAISRLCEAVPGANGAIKRRK PPVKFLSTVLGKSNLQFSGMNIKLTISTYSLTLMNLDNQQIIANHHMQSISFASGGDPDT TDYVAYVAKDPVNQRACHILECRNGMAQDVITTIGQAFELRFKQYLKNSSLNTSCESEEV HIDGHAEERDHEYYNEIPGKQPPAGGVSDVRIKVQAAEQMAYCPIRCEKLCYLPGNSKCS SVYENCLEQSRAIGNAHEREVQYQRDTSLMKHTCRVDLFDDPCYINTQALQSTLGSARNQ SSDHSLGSPWHREKAPETVQPGAMAQPASSHSLPHIKQQLRNEECYHGKLSRKAAESLLV KDGDFLVRESATSPGQYVLSGLQGGQAKHLLLVDPEGKVRTKDHVFDNVGHLIRYHMDNS LPIISSGSEVSLKQPVRKDNNPGLLHSNK >Gallus gallus_SHC4(ENSGALP_8011) MRERGPQSLGAHVLYVGLLRHPGMLHRAKYSRFRNDSVTSLDEGPQNIKGSSSSSHPSAP NLLAEDVPLGPQDACTTLCALIPRVANIKLANPSALPSLKGFCLGSKEVPRTKLTECVAV PGGPSSPELGCLSASYPQPGPEGPHLTPRPAGGCTGRGAAEAVSRLGGSLVPSGESAEEP GTTYSVRYMGCIEVLQSMRSLDFGTRTQVTREAISRLCEAVSGTNGAIRKRKPPVKFLSS VLGKSNLQFSGVNIKLTISTNSLTLINVDTQQIIANHHMQSISFASGGDPDTTDYVAYVA KDPVNQRACHILECPNGMAQEVINTIGQAFELRFKQYLKNPSSLVTSNESEAVSADGSAG NLQEREDHEYYNEIPGKEPPAGGVLDMRMKVPTDQRSGCFIQCKKQHCLTGSPTFINIYE NCPEENKTVGPCAERSQKTKKDATLLKSAYRTDLFDDPCYINTQALQSAVCTARGTAATQ IHGSPRSHTKLPETVQQSATSNTAGLCVLPQIKQQLRNEDCYHGKLNRKAAESLLVNDGD FLVRESTTSPGQYVLSGLQGGQAKHLLLVDPEGKVRTKDRIFDSVGHLIQYHMENNLPII SSGSEVSLKQPVRKESNMGHLHYHK >Pelodiscus sinensis_SHC4(ENSPSIP_12922) MRERSQHSLSGHALYVGLFRHPGMLHRAKYSRFRDDSITSLEEGTQNSSLNIKGSSSSSL SSTPHLPIEDVNLGTQDSSTTLCTLIPRMANIKLSNPSNLPGLKNFCLGTKEVPRIKLTE CVTVPGSPTSPEISLLSCLPASYPRQDPEKLDVNTKSQDDCVLLGFESASLSKQDSPLVQ SGEGIVKTGMTYCVRYMGCIEVLQSMRSLDFGTRTQVTREAISRLCEAVSGTNGAIKKRK PPVKFLSSVLGKSNLQFSGMNIKLIISMSSLTLMNVDNQQIIANHHMHSISFASGGDPDT TDYVAYVAKDPVNQRACHILECPNGMAQSVINTIGQAFELRFKQYLKNPSTLITSNESEV MNLDGSAWNIQEREDHDYYNEIPGKEPPTGGLLDMRMKVQMDQRANCPIQCEKQYGLAGS PKCINIYENCPEENKSVGNCGERSLKAKKDVSLLKPACKMDLFDDPCYINTQTLQTTAYT ARGLASAQVYGSPLCHEKLTEAVQQHATTNMDSACVLSQIKQQLRNEDCYHGKLNRKAAE TLLVNDGDFLVRESATSPGQYVLSGLQGGQAKHLLLVDPEGKVRTKDHVFDSVGHLIRYH MENNLPIISSGSEVSLKQPVRKKSNIGHMQYNK >Ciona intestinalis _(ENSCINP_13182) MRRNKKLVEGDQTNEWRKSGSFVNKPQRGWLHPDSSVMGPGVVYSVQYLGCVEVRQSMRT LDFDMRTLATKEAIWRVLASTGMSPLPPAANRSGRKKPPKDVTRILGERPNLKFSQSFIN LTISTASLTLVVSNTGQFIANHQMQSISFASGGDPDTIDYVAYVAKDPINSRACHVLKCT DGLAQDVINTIGQAFELRFKEYLKNPPKAVTPPDRTEPLFHDGKSRWGDDEPEYYNEIPG KLAPESGLKRLDDGSKIDEGAVVYPNHHNSQEYINNGMQSECSAPTPTLSTPTPRRTPRN FEDHNYVNTCVMPHGQEPTNQKRPSVDAFDMRPFANTLNPPATPTSATNALQSKPWFHGH VTRKEAEQLLSHDGDFLVRESTTTKGQFVLSGVQDGQYKHLLLVDPNGVVRTKDRQFDSV SHLISFHRDNTLPIVSSGSVLLLRQPVTRQIER >Branchiostoma floridae _(XP_002608644) MVATTTWAGITGFPLTFKRKATWEVLSTPGGDGVSPCTTSAHAFLSDMTAARSSSASPVSLESSLGKETQ DYVAYVAKDXVNSRACHVLHCPGGLAQDVITTIGQAFELRFKDFLKNPPKAVSAPDRLEDPIFEEGESAW GDDPEYYNEIPGKLPPTGGMPPPLPAGPPPGHYQAPSNLQASDGVYSSVKDAPSRPGPTYDNKASADNLI DFTAETPTAPVYDNPLHEPAGRGPPVSHGNDLPPEAAQPRSEVSLFDDPTYDNRRIENRPMHPDPMGAQQ PPQQPPQRPPLPLPAQDPFNMGPFDAGLQQDPASPPHPLYQEEWFHGPMTRKQAEELLEEDGDFLVRESE RKYDITGPVVLTCLCLCAGERKYNITGPVVLTCLCLCAGERKYDITGPVVLTCLCLCAGERKYDITGPVV LTACWRQSQTPATGGPTGHKLE >Apis mellifera _(XP_395635) MATGGSSFISKPARGWLHPDHLVSKEGITYTVKYIGCLEVYTSMKSLDFETRSCVAKECINRVCEAAGLK SADKKRRVDRKVLRAIADKPRMEHTGATINLTISSCSLALTNIENGHIIAKHEMPRISFASGGDTEILDF VAYVAKNMQEWRACYVLECGGGLAQDVISTIGQAFELRFKEFLTKPASLHPILNGIREADRDYYNDLPGK VPPDIGPPPVPPLPTSASTLPNLKHHHSVQNHISRSNIQNSGLHDTFSISSDRHHQQWAETGNLIDLNSD GTSTNFNIPPEHNYVNDSVIAASRENQRDQTSLFDVFDMQPFSSAISDMNKLSPHSQKQQLKQEIWFHGS VSRAEAESMLTRDGDFLVRESQGSPGQYVLTGMNNNTPKHLLLIDPEGVVRTKDRVFDSVSHLVNHHCDN VLPIISADSVLVLRYPIPRRTNN >Caenorhabditis elegans _(F54A5) MLNVEPSFAEELRSSGVSLSATYLGSVPVVESINVMVSEMRVQVVSECIQHVAATVGVTA AREINPVVSRVIGEVKKENFPVDINISSKMIKIIKQSRLIQRHPFSFFSFGAQGQKGTDT ELMFGYIAKNKDGTDRRCHVVFIEDVHKLIDVLTTAINVNTFDAQANASTSNDGFTVPAP PMRHRSSLHRQSFVSNCRAPTVTEDVVGKVWYHGNLSREDAQALLKTEGDFLVRQSDHTP GKYVLSGRTAENEHKHLILLDNHNRVRTRDRTFSNISELIDYHVNNGMAVRSEGRDRETS LNLIRPVPCPGSDDIE >Anopheles gambiae _(XP_317844) MPRNGEASSGLEKGVSSSKTAPEWLHPDHVIMNEGVTFDVRYIGCLEIKASMKKLDFPTRSQVAKECINR VCEAASLKSSKKRRVDKRVLQCISDTPDMEHAGTNVTLTVSSKYLSLVNVDTGEIIAKHDMPRISFASGG DTDTLDFVAYVAKDLNEWRACYVLECGGSLTQDLIATVGQAFELRYKEFFKQPETQSKFHELTRTDKVYY NDLPDKMPPDLLTENDHHSSSQSHSSSSAKVDAVQGQTRERIPSNLIDLNTPLPCHDYVNDKHANATNNS HSNKSISSSTIVKDVFDMRKSQLLTESWYHGSISRAQSEHLLKNDGDFLVRESAGTQGQYVLTGMQNNSP KHLLLIDPEGIVRTKDRVFDSISHLINFHWTNSLPIISAESALLLRHPILRTTDLLSKAKLAHLNLQ