>Homo sapiens_LEF1(ENSP_265165)
MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE
SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM
NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS
KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWQGQPVYPITGGFRQPYPSSLSVDTSMS
RFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIK
KPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHM
QLYPGWSARDNYGKKKKRKREKLQESASGTGPRMTAAYI

>Macaca mulatta_LEF1(ENSMMUP_34904)
MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE
SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM
NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS
KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWQGQPVYPITGGFRQPYPSSLSVDTSMS
RFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIK
KPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHM
QLYPGWSARDNYGKKKKRKREKLQESTSGTGPRMTAAYI

>Mus musculus_LEF1(ENSMUSP_29611)
MPQLSGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNESE
IIPASNGHEVVRQAPSSQEPYHDKAREHPDEGKHPDGGLYNKGPSYSSYSGYIMMPNMNS
DPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQ
GMSRHPPAPEIPTFYPLSPGGVGQITPPIGWQGQPVYPITGGFRQPYPSSLSGDTSMSRF
SHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKP
LNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQL
YPGWSARDNYGKKKKRKREKLQESTSGTGPRMTAAYI

>Loxodontaafricana_LEF1(ENSLAFP_13798)
MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE
SEIIPASNGHEVARQAQTSQESYHDKAREHPDEGKHPDGGLYNKGPSYSGYSGYIMMPNM
NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS
KQGMPRHPPAPDIPTFYPLSPGGVGQITPPLGWQGQPVYPITGGFRQPYPSSLSVDTSMS
RFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIK
KPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHM
QLYPGWSARDNYGKKKKRKREKLQESTSGTGPRMTAAYI

>Anolis carolinensis_LEF1(ENSACAP_7988)
MPQLSGGGGGGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKS
SLVNESETISSSNGHEVSRQGQPQEIYHDKGREHPEEGKHTDGGLYGKGPSYSGYSGYIM
MPNMNNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGTHPSHLPS
DVNSKQGMSRHPPGPDMPTFYPLSPGSVGQITPPLGWQGQPVYPISSGFRQPYPSSLSVD
TSMSRFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKR
PHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKER
QLHMQLYPGWSARDNYGKKKKRKREKLQESTSGAAPRMTAAYI

>Xenopus tropicalis_LEF1(ENSXETP_45617)
MPQLSGAGGGNGGGGDPELCATDEMIPFKDEGDPQKEKIYAEISNPEEEGDLADIKSSLV
NETEIIPSSNSHEISRRRQDSYHEKSREHPEDGKHPDGGLYSKGPSYTGYPSYIMMPNMN
NEPYMSNGSLSPPIPRTSNKVPVVQPSHAIHPLTPLITYSDEHFAPGAHPSHIPSDVNSK
QGMHRHPQAPDLPTFYPLSPGSVGQMTPPLGWYPHHMVSGPPGPHATGIPHPAIVNPQVK
QEHPHNDNDLMHMKPHHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAI
NQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESTSG
VCAELHLLWV

>Takifugu rubripes_LEF1(ENSTRUP_21715)
MEGGGGGGEGRGGGEGGGGGGGQGCGGGDPELCATDEMIPFKDEGDPHKEQIFAELSHSE
EEGDLADIKSSLVNESESSPNSNSHDGVRQSQIPDSYHEKHRDHQEDEERGKLQDLYCKG
HPYSGYPSYSMMSNMDASYMNNGSLSPPMPRTEVYIQTLWALLDMPSHGNGRDTQRPPPD
SISNKVPVVQPSHAVHPLTPLITYSDEHFAPGSHSGHHPHDGSNKQGMPRQHPGPDMANF
YSLSPGGVGQITPPLGWLLQRRGRHPYDIQLYHLLPFLPPICLCSSCVSGLFSHHMVPGP
PGPHATGIPHPAIVNPQIKHEPLHETDIMHMKPQHEQRKDQEPKKPHIKKPLNAFMLYMK
EMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDN
YGKKKKRKREK

>Tetraodon nigroviridis_LEF1(ENSTNIP_21188)
MPQLSGGGGDPELCATDEMIPFKDEGDPHKEQIFAELSHSEEEGDLADIKSSLVNESESS
PNSNSHGVRQSQIPDSYHEKHRDHQEDVGKLQDLYSKGHPYSGYPSYSMMSNMNDSSYMN
NGSLSPPMPRTHLYTTHTHICVYNTHAHQIKSNYLQSGKWSTVKNQGGSLMSKQEQLSFR
SPPHPHIPESNKVPVVQPSHAVHPLTPLITYSDEHFAPGSHSGHHPHDGSSKQGMPRQHP
GPDMPNFYSLSPGGVGQITPPLGWFCFVFFPFFLPNYRNFSPLFQLMLTDISTFSHHMVP
GPPGPHATGIPHPAIVNPQIKHEPLHETDIMHMKPQHEQRKDQEPKKPHIKKPLNAFMLY
MKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSAR
DNYGKKKKRKREK

>Gasterosteusaculeatus_LEF1(ENSGACP_23070)
MPQLSGGGGDPELCATDEMIPFKDEGDPHKEQIFAELSHSEEEGDLADIKSSLVNESESS
PNSNSHDGARLSQIPQDSYHEKHRDHLEDGKLQDLYSKGHPYQGYPGYIMMSNMNDSYMN
NGSLSPPMPRTSNKVPVVQPSHAVHPLTPLITYSDEHFAPGPHPQDVNNKQACLGMQRHH
QGPDMTNFYSLSPGGVGQLTPPLGWFSHHMVPGPQGPHATGIPHPAIVNPQVKHEPLHET
DIMHMKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRK
QWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKMQESAPGTGQRMK
TAYIs

>Oryzias latipes_LEF1(ENSORLP_8700)
MPQLSGGGGGDPELCATDEMIPFKDEGDPHKEQIFAELSHSEEEGDLADIKSSLVNESES
SPNSNNHDAARQSQIPPDSYHEKHRDLIEDERGKHADMYGKGHVYPSYPGYIMMNMNSDS
YMNNGSLSPPMPRTYNFFKWDYITVQTESVVTTQTLCDLHSESNSHLASNKVPVVQPSHA
VHPLTPLITYSDEHFAPGSHSGLHPQDANNKQGMPRHHPGPDMPNFYSLSPGGVGQITPP
LGWLNTREGPKCDPTGCHRKSLFSTSLQSLKNPLHSRMFSHHMVPGPPGPHATGIPHPAI
VNPQIKHEPPHETDIMHIRKPQHEQRKEQEPKKPHIKKPLNAFMLYMKEMRANVVAECTL
KESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREK>Homo sapiens_LEF1(ENSP_265165)
MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE
SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM
NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS
KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWQGQPVYPITGGFRQPYPSSLSVDTSMS
RFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIK
KPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHM
QLYPGWSARDNYGKKKKRKREKLQESASGTGPRMTAAYI

>Macaca mulatta_LEF1(ENSMMUP_34904)
MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE
SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM
NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS
KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWQGQPVYPITGGFRQPYPSSLSVDTSMS
RFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIK
KPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHM
QLYPGWSARDNYGKKKKRKREKLQESTSGTGPRMTAAYI

>Mus musculus_LEF1(ENSMUSP_29611)
MPQLSGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNESE
IIPASNGHEVVRQAPSSQEPYHDKAREHPDEGKHPDGGLYNKGPSYSSYSGYIMMPNMNS
DPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQ
GMSRHPPAPEIPTFYPLSPGGVGQITPPIGWQGQPVYPITGGFRQPYPSSLSGDTSMSRF
SHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKP
LNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQL
YPGWSARDNYGKKKKRKREKLQESTSGTGPRMTAAYI

>Loxodontaafricana_LEF1(ENSLAFP_13798)
MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE
SEIIPASNGHEVARQAQTSQESYHDKAREHPDEGKHPDGGLYNKGPSYSGYSGYIMMPNM
NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS
KQGMPRHPPAPDIPTFYPLSPGGVGQITPPLGWQGQPVYPITGGFRQPYPSSLSVDTSMS
RFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIK
KPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHM
QLYPGWSARDNYGKKKKRKREKLQESTSGTGPRMTAAYI

>Anolis carolinensis_LEF1(ENSACAP_7988)
MPQLSGGGGGGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKS
SLVNESETISSSNGHEVSRQGQPQEIYHDKGREHPEEGKHTDGGLYGKGPSYSGYSGYIM
MPNMNNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGTHPSHLPS
DVNSKQGMSRHPPGPDMPTFYPLSPGSVGQITPPLGWQGQPVYPISSGFRQPYPSSLSVD
TSMSRFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKR
PHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKER
QLHMQLYPGWSARDNYGKKKKRKREKLQESTSGAAPRMTAAYI

>Xenopus tropicalis_LEF1(ENSXETP_45617)
MPQLSGAGGGNGGGGDPELCATDEMIPFKDEGDPQKEKIYAEISNPEEEGDLADIKSSLV
NETEIIPSSNSHEISRRRQDSYHEKSREHPEDGKHPDGGLYSKGPSYTGYPSYIMMPNMN
NEPYMSNGSLSPPIPRTSNKVPVVQPSHAIHPLTPLITYSDEHFAPGAHPSHIPSDVNSK
QGMHRHPQAPDLPTFYPLSPGSVGQMTPPLGWYPHHMVSGPPGPHATGIPHPAIVNPQVK
QEHPHNDNDLMHMKPHHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAI
NQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESTSG
VCAELHLLWV

>Takifugu rubripes_LEF1(ENSTRUP_21715)
MEGGGGGGEGRGGGEGGGGGGGQGCGGGDPELCATDEMIPFKDEGDPHKEQIFAELSHSE
EEGDLADIKSSLVNESESSPNSNSHDGVRQSQIPDSYHEKHRDHQEDEERGKLQDLYCKG
HPYSGYPSYSMMSNMDASYMNNGSLSPPMPRTEVYIQTLWALLDMPSHGNGRDTQRPPPD
SISNKVPVVQPSHAVHPLTPLITYSDEHFAPGSHSGHHPHDGSNKQGMPRQHPGPDMANF
YSLSPGGVGQITPPLGWLLQRRGRHPYDIQLYHLLPFLPPICLCSSCVSGLFSHHMVPGP
PGPHATGIPHPAIVNPQIKHEPLHETDIMHMKPQHEQRKDQEPKKPHIKKPLNAFMLYMK
EMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDN
YGKKKKRKREK

>Tetraodon nigroviridis_LEF1(ENSTNIP_21188)
MPQLSGGGGDPELCATDEMIPFKDEGDPHKEQIFAELSHSEEEGDLADIKSSLVNESESS
PNSNSHGVRQSQIPDSYHEKHRDHQEDVGKLQDLYSKGHPYSGYPSYSMMSNMNDSSYMN
NGSLSPPMPRTHLYTTHTHICVYNTHAHQIKSNYLQSGKWSTVKNQGGSLMSKQEQLSFR
SPPHPHIPESNKVPVVQPSHAVHPLTPLITYSDEHFAPGSHSGHHPHDGSSKQGMPRQHP
GPDMPNFYSLSPGGVGQITPPLGWFCFVFFPFFLPNYRNFSPLFQLMLTDISTFSHHMVP
GPPGPHATGIPHPAIVNPQIKHEPLHETDIMHMKPQHEQRKDQEPKKPHIKKPLNAFMLY
MKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSAR
DNYGKKKKRKREK

>Gasterosteusaculeatus_LEF1(ENSGACP_23070)
MPQLSGGGGDPELCATDEMIPFKDEGDPHKEQIFAELSHSEEEGDLADIKSSLVNESESS
PNSNSHDGARLSQIPQDSYHEKHRDHLEDGKLQDLYSKGHPYQGYPGYIMMSNMNDSYMN
NGSLSPPMPRTSNKVPVVQPSHAVHPLTPLITYSDEHFAPGPHPQDVNNKQACLGMQRHH
QGPDMTNFYSLSPGGVGQLTPPLGWFSHHMVPGPQGPHATGIPHPAIVNPQVKHEPLHET
DIMHMKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRK
QWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKMQESAPGTGQRMK
TAYIs

>Oryzias latipes_LEF1(ENSORLP_8700)
MPQLSGGGGGDPELCATDEMIPFKDEGDPHKEQIFAELSHSEEEGDLADIKSSLVNESES
SPNSNNHDAARQSQIPPDSYHEKHRDLIEDERGKHADMYGKGHVYPSYPGYIMMNMNSDS
YMNNGSLSPPMPRTYNFFKWDYITVQTESVVTTQTLCDLHSESNSHLASNKVPVVQPSHA
VHPLTPLITYSDEHFAPGSHSGLHPQDANNKQGMPRHHPGPDMPNFYSLSPGGVGQITPP
LGWLNTREGPKCDPTGCHRKSLFSTSLQSLKNPLHSRMFSHHMVPGPPGPHATGIPHPAI
VNPQIKHEPPHETDIMHIRKPQHEQRKEQEPKKPHIKKPLNAFMLYMKEMRANVVAECTL
KESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREK

>Homo sapiens_TCF7(ENSP_378472)
MPQLDSGGGGAGGGDDLGAPDELLAFQDEGEEQDDKSRDSAAGPERDLAELKSSLVNESE
GAAGGAGIPGVPGAGAGARGEAEALGREHAAQRLFPDKLPEPLEDGLKAPECTSGMYKET
VYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAPADISQ
KQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPAIVPPS
GKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAIN
QILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTDP
GSPKKCRARFGLNQQTDWCGPCRRKKKCIRYLPGEGRCPSPVPSDDSALGCPGSPAPQDS
PSYHLLPRFPTELLTSPAEPAPTSPGLSTALSLPTPGPPQAPRSTLQSTQVQQQESQRQV
A

>Macaca mulatta_TCF7(ENSMMUP_30002)
HKANQPPHGVPQLSLYDHFNSPHPTPAPADVSQKQVHRPLQTPDLSGFYSLTSGSMGQLP
HTVSWFTHPSLMLGSSVPGHPAAIPHPAIVPPSGKQELQSFDRNLKTQAESKAEKEAKKP
TIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQ
LHMQLYPGWSARDNYGKKKRRSREKHQESTTDPGSPKKCRARFGLNQQTDWCGPCR

>Mus musculus_TCF7(ENSMUSP_84055)
MYKETVYSAFNLLMPYPPASGAGQHPQPQPPLHNKPGQPPHGVPQLSPLYEHFSSPHPTP
APADISQKQGVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWPSPPLYPLSPSCGYRQHFPA
PTAAPGAPYPRFTHPSLMLGSGVPGHPAAIPHPAIVPSSGKQELQPYDRNLKTQAEPKAE
KEAKKPVIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYEL
ARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTGGKRNAFGTYPEKAAAPAPFLPM
TVL

>Canis familiaris_TCF7(ENSCAFP_1404)
MPQLDAGGGGAGGGDLDAPEELLAFQDEGEEQDDKSRDSAAGPERDLAELKSSRVNESEG
AAGGAGVPGAGAGARGAAEVGAEALGREHASQRLFPDKLPESLEDGLKAPECASGMYKDT
VYSAFNLLMHYPPPSGAGQHPQPQPPLHNKASQPAHSVPQLSPLYEHFSSPHPTSAPADI
SQKQGVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWPSPPLYPLSPSCGYRQHFPAPTAAP
GAPYPRFTHPSLMLGSGVPGHPAAIPHPAIVPPSGKQELQPYDRSLKTQAESKVEKEAKK
PTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKER
QLHMQLYPGWSARDNYGKKKRRSREKHQESTTGGKRNAFGTYPEKAAAPAPFLPMTVL

>Bos taurus_TCF7(ENSBTAP_1329)
PQLDSGGGGAGGGDDLGAPDELLAFQDEGEEQDDKSRDSAAGPERDLAELKSSLVNESE
GAAGDAGVPGAGAGARGEAEVGAEALGREHTSQRLFPDKLPESLEDGLKAPECTSGMYKD
TVYSAFNLLMHYPPPSGAGQHPQPQPPLHNKASQPSHGVPQLSPLYDHFSSPHPTPAPAD
ISQKQGVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWPSPPLYPLSPSCGYRQHFPAPTAA
PGAPYPRFTHPPLMLGSGVPGHPAAIPHPAIVPSSGKQELQPYDRSLKAQADSKAEKEAK
KPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKE
RQLHMQLYPGWSARDNYGKKKRRSREKHQESNSGGKRNAFGTYPEKAAAPAPFLPMTVL

>Loxodontaafricana_TCF7(ENSLAFP_14110)
MPQLDSGGGSAGGGDDLGAPDELLAFQDEGEEQDKSRDSAAGPERDLAELKSSLVNESEG
AAGGAGVPGTGAEAEARAEALGREHTSQRLFSDKLPESLEDGLKAPECVSGMYKETVYSA
FNLLMHYPPPSGAGQHPQPQPPLHNKASQPPHGVPQLSPLYEHFSSPHPTPAPADINQKQ
VHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPAIVPPSGK
QELQPYDRSLKTQAEAKVEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQI
LGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESNTDPGS
PKKCRARFGLNQQTDWCGPCRRKKKCIRYLPGEGRCPSPVPSDDSALGCPGSPAPQDSPS
YLLLPHLPTELLASPAEPAPTSPGLCATLSLPATGPQQAPRRTLQSTQVQPQESQR

>Gallus gallus_TCF7(ENSGALP_10462)
MPQLGSGGGDDLGATDEMLAFKDEGEQEEKIPENAFTERDLADLKSSLVNESEGSGSPAA
AADPEAIRRVQDPQRVYQEKLPDHMDDAGMKHQDPGMYKGSAYSGYPFLMLSDPYLPNGS
MSPLSNKVPVVQPSHGVHPLTPLIPYSNDHFSHGSHSPHLPADISQKQAVHRPSQTSDIP
GFYPLPPAGVGQITPSMGWFTHPLMLGSGMHTTGIPHPAIVPHSGKQEMEHYDRNMKPQP
EPKREKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQA
KYYELARKERQLHMQLYPGWSARDNYGKKKRRTREKQQDSNSDPASPKKCRARFGLNQQT
DWCGPCSFLQQFQLLSKYLFEFLKPL

>Anolis carolinensis_TCF7(ENSACAP_2667)
MSPLSNKVPVGQPSHGVHPLTPLIPYSNEHFSHGSHSPHLPADISQKQGVHRPSQTSDIP
GFYSLPPTGVGQITSSMGWITHPLMLGSGMHTTGISHPGITSPGKQEMDHYDRSMKSQPE
PKREKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAK
YYELARKERQLHMQLYPGWSARDNYGKKKRRTREKQQDSNSGGKRSAFGTYKEDAVPAQF
LPMEVL

>Danio rerio_TCF7(ENSDARP_129238)
VPKHHDGGMYKAPYSGYPFLMLPEPYLPNGPVSPSSNKVSVVQQGMHPLTPLLPYEHFNP
SPTHMPTDGGQKPGVHRHQTQEISGFYSLPQGQITPSMNWFSHSLMLQSGMHPTGIPHPA
IVPPSGKQEHDQFDRSIYNKSHAEAKREKEPKKPVIKKPLNAFMLYMKEMRAKVIAECTL
KESAAINQILGRRWHALTREEQAKYYELARKERQLHMQLYPSWSARDNYVSALGKKKRRK
RDKQQDSSTEPGSPKKCRARFGLNQQTDWCGPCR

>Takifugu rubripes_TCF7(ENSTRUP_19133)
MPQLSSGGGDDLGANDEMIAFKDEGEQEEKIQENALTERDLADLKSSLVNESETNQSPNA
ASTPPQAIRRAQQGEQRGFAEKHREHLDGVSKHQDGGIYKTPTYPGYPFLMLPDPYLPNG
SVSPSSNKVSVVQQSHGMHPLSSLLPYGNEHFSPSPPHLPADMSQKPGVHRHQSQDLSGY
YSLPPGGVGQITPSMSWFPHPLMLGPSGMHPTGIPHPAIVPPTGKQDHDQYDRGMYLKQE
VKQQKEPKKPVIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALTREEQAK
YYELARKERQLHMQLYPTWSARDNYGKRKKRKREKLQDSGADPGSPKKCRARFGLNQQTD
WCGPCSSFATQKGQRNHFLSLFLSPL

>Tetraodon nigroviridis_TCF7(ENSTNIP_19182)
MPQLSSGGGDDLGANDEMIAFKDEGEQEEKIQENALTERDLADLKSSLVNESETNQSPNA
AAIRRAQQGEQRSFAEKHRELIDGVSKHQDGGMYKTPAYTGYPFLMLPDPYLPNGSVSPS
SRFPLICIWPLRMTAQAGHSRKRPVRIDVTGFSPVFVLQQSNKVSVVQQSHGMHPLSSLL
PYGNEHFSPSPPHLPADMSQKPGVHRHQSQDLSGYYSLPPGGVGQISPSVSWLLVRQGQA
VYPTLSPCGFRQPYASNLSSTPSSYSRFPHPLMLGPSGMHPTGIPHPAIVPPTGKQEHDQ
YDRGMYLKQEVKQQKEPKKPVIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRW
HALTREEQAKYYELARKERQLHMQLYPTWSARDNYGKKKEEKTGE

>Oryzias latipes_TCF7(ENSORLP_1191)
MPQLSSGGGDDLGANDEMISFKDEGEQEEKIQENAFTERDLADLKSSLVNESEISQSPSA
AAARRGHQGEQRGFPDKHREHLEGVSKQQDGSMYKSAAYPGYPFLMLPDPYLPNSSVSPS
QRTYIKKKRWRIISKQQKMLQRRTGVLHLENPTSAHIVDSNKVSVVQQSHGMHPLTSLLP
YSNDHFSPSPPHLPTDMSQKTGVHRHQSQDLSGYYSLPPGGVGQIPPSMSCFLPKQSQPV
YPGLSPCGFRQSYSSNLPRNFLSSFLPGTRFPHSLMLGPSGMHPTGIPHPAIVPPSGKQE
HDQYDRGILLSPIRKQQVETKREKEPKKPVIKKPLNAFMLYMKEMRAKVIAECTLKESAA
INQILGRRWHALTREEQAKYYELARKERQLHMQLYPTWSARDNYGKKKRRKREKQQDSNT
AHICTVQYPGVSLGITPGRSLRSDPGSPKKCRARFGLNQQTDWCGPCRLKFLDVCPPSSE
K

>Homo sapiens_TCF7L2(ENSP_348274)
MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS
DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS
LSPTARTLHFQSGSTHYSAYKTIEHQIAVQYLQMKWPLLDVQAGSLQSRQALKDARSPSP
AHIVSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDIS
PYYPLSPGTVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPP
HHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLY
MKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSAR
DNYGKKKKRKRDKQPGETNEHSECFLNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPC
RRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLGSPPRDAKSQTEQTQPLSLSLKP
DPLAHLSMMPPPPALLLAEATHKASALCPNGALDLPPAALQPAAPSSSIAQPSTSSLHSH
SSLAGTQPQPLSLVTKSLE

>Macaca mulatta_TCF7L2(ENSMMUP_30018)
LHFQSGSTHYSAYKTIEHQIAVQYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNK
VPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSP
GTVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTT
GIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAK
VVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKK
KRKRDKQPGETNEHSECFLNPCLSLPPITDANTPKKCRALFGLDRQTLWCKPCRRKKKCV
RYIQGEGSCLSPPSSDGSLLDSPPPSPNLLGSPPRDAKSQTEQTQPLSLSLKPDPLAHLS
MMPPPPALLLAEATHKASALCPNGALDLPPTALQPAAPSSSVAQPSTSSLHSHSSLAGTQ
PQPLSLVTKSLE

>Mus musculus_TCF7L2(ENSMUSP_107291)
MPQLNGGGGDDLGANDELISFKDEGEQEEKNSENSSAERDLADVKSSLVNESETNQNSSS
DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS
LSPTARTYLQMKWPLLDVQAGSLQSRQTLKDARSPSPAHIVSNKVPVVQHPHHVHPLTPL
ITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQ
QGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQES
SQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQI
LGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNDLSA
PKKCRARFGLDQQNNWCGPCRDANTPKKCRALFGLDRQTLWCKPCRRKKKCVRYIQGEGS
CLSPPSSDGSLLDSPPPSPHLLGSPPQDAKSQTEQTQPLSLSLKPDPLAHLSMMPPPPAL
LLAEAAHGKASALCPNGALDLPPAALQPSMVPSSSLAQPSTSSLHSHNSLAGTQPQPLSL
VTKSLE

>Gallus gallus_TCF7L2(ENSGALP_32466)
MPQLNGGGGDDLGANDELISFKDEGEQEEKISENSSAERDLADVKSSLVNESETNQNSSS
DSEAERRPPPRSETFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLSSPYLPNGS
LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPL
ITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQ
QGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHSLHTTGIPHPAIVTPTVKQES
SQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQI
LGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEHSE
CFLNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPCRRKKKCVRYIQGEGSCVSPPSSD
GSLLDSPPSSPAMLASPSRDSKPQTEQTQPLSLSLKPDPLAHLVMMPPPSSLVLAESAAS
KPGALPAASCPNGALDHAPAALPPAASLAQPSTSSLHSHSSLAGPQPQPLSLVTKSLE

>Anolis carolinensis_TCF7L2(ENSACAP_10302)
MKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPLITYSNEHFTP
GNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGAVGQIPHPLGWLVPQQGQPVYPITT
GGFRHPYPTALTVNASMSRFPPHMVPPHHSLHTTGIPHPAIVTPTVKQESSQNDVGSLHS
SKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSR
EEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNGKTQRMFLNPCLSL
PPITDLSAPKKCRARFGLDQQNNWCGPCRRKKKCVRYIQGEGSCVSPPSSDGSLLDSPPS
SPNMLASPTRDSKSQTEQTQPLSLTLKPDPLAHLPLMPPASSSSVVLTESSTSKPRGLPA
SNCQNGALDHQSATLQQSAPSSSSLVQPSTSSLHSHNSLAGTQPQPLSLVTKSLE

>Xenopus tropicalis_TCF7L2(ENSXETP_40616)
SNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLQADVDPKTGIPRPPHPPDISPYYP
LSPGAVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHSL
HTTGIPHPAIVTPTVKQESSQSDMGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEM
RAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYG
KKKKRKREKQQGEANEHSECYLNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPCRRKK
KCIRYIQGEGSCVSPPSSDGSLLDSPPSSPAMPDSPASDSKPQTEQTQPLSLSLKPDPLA
RICVPHSPLAQSPARKPSALPVTICQNGAEHAHPHNVLQSSLPYGLSLTQPSTSFLPSHR
SLAGTTQLQPLSLVTKPLE

>Danio rerio_TCF7L2(ENSDARP_30292)
MPQLNGGGGDDLGANDEMISFKDEGEQEEKISENSSAERDLADVKSSLVNESETNQNSSS
DSEAERRPPPRSESFRDKTRESLEEAAKRQDGGLFKSPPYPGYPFIMIPDLTSPYLPNGS
LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPL
ITYSNEHFTPGNPPPHLQADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQ
QGQPVYPITTGGFRHPYPTALTVNASMSSLLSSRFPPHMVPPHHSLHTTGIPHPAIVTPN
VKQESSHSDIGSLNSSKHQDAKKEEEKKKQPHIKKPLNAFMLYMKEMRAKVVAECTLKES
AAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKQAGE
GNEHREYFPNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPCRRKKKCIRYIQGEGSCA
SPPSSDGSLLESPPSSPSMISPSPSSKESKPQTEQMQPLSLTMKPPPLLSSSQHQHLSMA
PPPPLALLDNSGAGKTSGSAHNGSLDPSDVSSSRSTGSASSRPISACHSHSLLPSSAPTQ
PLSLVTKSID

>Takifugu rubripes_TCF7L2(ENSTRUP_31774)
MPQLNGGGGDDLGANDEMISFKDEGEQEEKISENSSAERDLADVKSSLVNESETNQNSSS
DSEAERRPPPRSETFRDKTRESLEEAAKRQDGGLFKSPPYPGYPFIMIPDLTSPYLPNGS
LSPTARTYLQMKWPLLDVQPGGLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPL
ITYSNEHFTPGNPPPHLQTDVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQ
QGQPVYPITTGGFRHPYPTALTVNASMSSLLSSRFPPHMVPPHHSLHTTGIPHPAIVTPN
VKQESTHSDINSLNSSKQSDSKKEPEKKKEVHIKKPLNAFMLYMKEMRAKVVAECTLKES
AAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKRKKRKREKQQQA
EGNEHREYFPNPCLSLPPITAASDLSAPKKCRARFGLDQQNNWCGPCRRKKKCIRYIQGE
GSCASPPSTDGSLLDSPPSSPSSVVPSPSPKESKPQTEQMQPLSLTMKPAHQPLHHPHLL
AGPTPPLVQLENSAAASKTPGASSHNGALEHVNVSSSRQRGSSVVPSMARPSASLCHSQS
LLPAQPLSLVTKSIE

>Tetraodon nigroviridis_TCF7L2(ENSTNIP_13209)
ILQSPFTQILTYFVSPFSFLQSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLQTD
VDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTA
LTVNASMSSLLSSRFPPHMVPPHHSLHTTGIPHPAIVTPNVKQESTHSDINSLNSSKQSD
SKKEPEKKKEVHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQA
KYYELARKERQLHMQLYPGWSARDNYGKRKKRKREKQQQAEGNGKRKKKCIRYIQGEGSC
ASPPSTDGSLLDSPPSSPSSVVPSPSPKESKPQTEQMQPLSLTMKPAHQPLHHPHLLAGP
TPSLVQLENTAAASKTPGTSSHNGALEHGDVSSSRQRGSSVVPSMARPSASLCHSQSLLP
TAPQPLSLVTKSIE

>Oryzias latipes_TCF7L2(ENSORLP_10533)
QSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLQTDVDPKTGIPRPPHPPDISPYY
PLSPGTVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHS
LHTTGIPHPAIVTPNVKQESSHSDISSLNSSKQSDAKKEEEKKKQVHIKKPLNAFMLYMK
EMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDN
YGKRKKRKREKQQAESNASDLSAPKKCRARFGLDQQNNWCGPCRC

>Homo sapiens_TCF7L1(ENSP_282111)
MPQLGGGGGGGGGGSGGGGGSSAGAAGGGDDLGANDELIPFQDEGGEEQEPSSDSASAQR
DLDEVKSSLVNESENQSSSSDSEAERRPQPVRDTFQKPRDYFAEVRRPQDSAFFKGPPYP
GYPFLMIPDLSSPYLSNGPLSPGGARTYLQMKWPLLDVPSSATVKDTRSPSPAHLSNKVP
VVQHPHHMHPLTPLITYSNDHFSPGSPPTHLSPEIDPKTGIPRPPHPSELSPYYPLSPGA
VGQIPHPLGWLVPQQGQPMYSLPPGGFRHPYPALAMNASMSSLVSSRFSPHMVAPAHPGL
PTSGIPHPAIVSPIVKQEPAPPSLSPAVSVKSPVTVKKEEEKKPHVKKPLNAFMLYMKEM
RAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKERQLHSQLYPTWSARDNYG
KKKKRKREKQLSQTQSQQQVQEAEGALASKSKKPCVQYLPPEKPCDSPASSHGSMLDSPA
TPSAALASPAAPAATHSEQAQPLSLTTKPETRAQLALHSAAFLSAKAAASSSGQMGSQPP
LLSRPLPLGSMPTALLASPPSFPATLHAHQALPVLQAQPLSLVTKSAH

>Macaca mulatta_TCF7L1(ENSMMUP_26509)
MPQLGGGGGGGGGGCSGGGSGSSAGAAGGGDDLGANDELIPFQDEGSEEQEPSSDSASAQ
RDLDEVKSSLVNESENQSSSSDSEAERRPQPARDTFQKPRDYFADVRRPQDSAFFKGPPY
PGYPFLMIPDLSSPYLSNGPLSPGGARTYLQMKWPLLDVPSSATVKDTRSPSPAHLSNKV
PVVQHPHHMHPLTPLITYSNDHFSPGSPPTHLSPEIDPKTGIPRPPHPSELSPYYPLSPG
AVGQIPHPLGWLVPQQGQPVYSLPPGGFRHPYPALAMNASMSSLVSSRFSPHMVAPAHPG
LPTSGIPHPAIVSPIVKQEPAPPSLSPAVSAKSPVTVKKEEEKKPHVKKPLNAFMLYMKE
MRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKERQLHSQLYPTWSARDNY
GKKKKRKREKQLSQTQSQQQVQEAEGALASKSKKPCVQYLPPEKPCDSPASSHGSMLDSP
ATPSAALASPAAPAATHSEQAQPLSLTTKPETRAQLALHSAAFLSAKAAASSSGQMGSQP
PLLSRPLPLGSMPTALLASPPSFPATLHAHQALPVLQAQPLSLVTKSAH

>Mus musculus_TCF7L1(ENSMUSP_109687)
MPQLGGGRGGGAGGGGGGSGAGATSGGDDLGANDELIPFQDEGGEEQEPSSDSASAQRDL
DEVKSSLVNESENQSSSSDSEAERRPQPARDAFQKPRDYFAEVRRPQDGAFFKGPAYPGY
PFLMIPDLSSPYLSNGPLSPGGARTYLQMKWPLLDVPSSATVKDTRSPSPAHLYGDPARW
MVPPTFRSNKVPVVQHPHHMHPLTPLITYSNDHFSPASPPTHLSPEIDPKTGIPRPPHPS
ELSPYYPLSPGAVGQIPHPLGWLVPQQGQPMYSLPPGGFRHPYPALAMNASMSSLVSSRF
PHMVAPAHPGLPTSGIPHPAIVSPIVKQEPAAPSLSPAVSAKSPVTVKKEEEKKPHVKKP
LNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKERQLHAQL
YPTWSARDNYGKKKKRKREKQLSQTQSQQQIQEAEGALASKSKKPCIQYLPPEKPCDSPA
SSHGSTLDSPATPSAALASPAAPAATHSEQAQPLSLTTKPEARAQLALHSAAFLSAKAAA
SNSSQMGSQPPLLSRPLPLGSMPAALLTSPPTFPATLHAHQALPVLQAQPLSLVTKSAH

>Rattus norvegicus_TCF7L1(ENSRNOP_20005)
MPQLGGGRGGGAGGGGGGSGAGATSGGDDLGANDELIPFQDEGGEEQEPSSDSASAQRDL
DEVKSSLVNESENQSSSSDSEAERRPQPARDAFQKPRDYFAEVRRPQDGAFFKGPAYPGY
PFLMIPDLSSPYLSNGPLSPGGARTYLQMKWPLLDVPSSATVKDTRSPSPAHLSNKVPVL
QHPHHLQHPLTPLITYSNDHFSPASPPTHLSPEIDPKTGIPRPPHPSELSPYYPLSPGAV
GQIPHPLGWLVPQQGQPMYSLPPGGFRHPYPALAMNASMSSLVSSRFSPHMVAPAHPGLP
TSGIPHPAIVSPIVKQEPAPPSLSPAVSAKSPVTVKKEEEKKPHVKKPLNAFMLYMKEMR
AKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKERQLHAQLYPTWSARDNYGK
KKKRKREKQLSQTQSQQQIQEAEGALVSKSKKPCIQYLPPEKPCDSPASSHGSTLDSPAT
PSAALASPAAPAATHSEQAQPLSLTTKPETRAQLALHSAAFLSAKATASNSSQMGSQPPL
LSRPLPLGSMPTALLTSPPSFPATLHAHQTLPVLQAQPLSLVTKSAH

>Canis familiaris_TCF7L1(ENSCAFP_11603)
GGGGGGGGGGGGGGGGSGAGAAGGGDDLGANDELIPFQDEGGEEQEPSSDSASAQRDLDE
VKSSLVNESENQSSSSDSEAERRPQPARDAFQKPRDYFAEVRRPQDGAFFKGPPYPGYPF
LMIPDLSSPYLSNGPLSPGGARTYLQMKWPLLDVPSSTTVKDTRSPSPAHLSNKVPVVQP
PHHMHPLTPLITYSNDHFSPGSPPTHLSPEIDPKTGIPRPPHPSELSPYYPLSPGAVGQI
PHPLGWLVPQQGQPMYSLPPGGFRHPYPALAMNASMSSLVSSRFSPHMVAPAHPGLPTSG
IPHPAIVSPIVKQEPAPPSLSPAVSAKSPVTVKKEEEKKPHVKKPLNAFMLYMKEMRAKV
VAECTLKESAAINQILGRKWHNLSREEQAKYYELARKERQLHSQLYPTWSARDNYGKKKK
RKREKQLSQTQSQQQVQEAEGALASKSKKPCVQYLPPEKSCDSPASSHGSMLDSPATPSA
ALASPAAPAATHSEQAQPLSLTTKPESRAQLALHSAAFLSAKATATSSGQMGSQPPLLSR
PLPLGSLPTALLTSPPSFPATLHAHQALPVLQAQPLSLVTKSAH

>Bos taurus_TCF7L1(ENSBTAP_13336)
YLQMKWPLLDVPASATVKDARSPSPAHLSNKVPVVQHPHHMHPLTPLITYSNDHFSPGSP
PTHLSPEIDPKTGIPRPPHPSELSPYYPLSPGAVGQIPHPLSWLVPQQGQPMYSLPPGGF
RHPYPALAMNASMSSLVSSRFSPHMVAPTHPGLPTSGIPHPAIVSPIVKQEPAPPSLSPA
VSAKSPVTVKKEEEKKPHVKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNL
SREEQAKYYELARKERQLHSQLYPTWSARDNYGKKKKRKREKQLSQTQSQQQQVQETDGA
LASKSKKPCVQYLPPEKPCDSPASSHGSMLDSPATPSAALASPAAPAATHSEQAQPLSLT
TKPETRAQLALHSAAFLSSKAAATSSGQMGSQPPLLSRPLPLGSVPTALLTSPPSFPATL
HTHQALPVLQAQPLSLVTKSAH

>Loxodontaafricana_TCF7L1(ENSLAFP_13665)
MPQLGGGGAGGGGGGGGSGAGAAGGGDDLGANDELIPFQDEGSEEQEPSSDSASAQRDLD
EVKSSLVNESENQSSSSDSEAERRPQPARDAFQKPRDYFAEVRRPQDGAFFKGPPYPGYP
FLMIPDLSSPYLPNGPLSPGGARTYLQMKWPLLDVPSSSTVKDTRSPSPAHLVSLPSPWQ
LFLSVFQSNKVPVVQHPHHMHPLTPLITYSNDHFSPGSPPTHLSPEIDPKTGIPRPPHPS
ELSPYYPLSPGAVGQIPHPLGWLVPQQGQPMYSLPPGSFRHSYPALAMNASMSSLVSSRF
SPHMVAPAHPGLPTSGIPHPAIVSPIVKQEPTPPSLSPAVSVKSPVTVKKEEEKKPHVKK
PLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKERQLHSQ
LYPTWSARDNYGKKKKRKREKQLSQTQSQQQAQEAEGALASKSKKPCVQYLPPEKPCDSP
ASSHGSMLDSPATPSAALASPAAPAATHSEQAQPLSLTTKPETRAQLALHSAAFLSAKAA
GTSSSQMGSQPPLLSRPLPLGSMPTALLTSPPSFPATLHAHQALPVLQAQPLSLVTKSAH

>Anolis carolinensis_TCF7L1(ENSACAP_11233)
MPQLQPDPGAAERSRDGGGGGSGDDLGAPDELIPFQDEGDEQDKGAGGRGSAHGDLDELK
SSLVHESESRGAGGGGGSSSESEAERPPPPPRPRESFQKPRDSPASVAEVLRRQQDGGFF
KGTPYPSYPFLMIPELGSPYLQSGALSPGGARTYLQVKWPLLDVPAGATLKDTRSPSPAH
LSNKVPVVQHAHHMHPLTPLITYSNDHFSPGSPPSHLSPEIDPKTGIPRPPHPSELSPYY
PLSPGAIGQIPHPLGWIVPQQGQPVYSIPPGGFRHPYPALAMNASMSSLMSSRFSPHMVP
PPAHGLHPSGIPHPTIVSPIVKQEPTQPSMSPEGSSKTPVIVKKEEEKKPHIKKPLNAFM
LYMKEMRAKVVAECTLKESAAINQILGRRWHSLSREEQAKYYELARKERQLHSQLYPTWS
ARDNYGKKKKRKREKQPQQQIQETGNSVALKSKKPCVPYLPAEKSCDSPASSHGSMLDSP
ATPSAALASPAAPAATHSEQAQPLSLTTKPEARAQLSLHSASFLASKASSSSLTGQSTLL
SRPLPFTSMPPTALLSSPPSFAAIPSPQAALAMLQAQPLALVTKPAE

>Xenopus tropicalis_TCF7L1(ENSXETP_45614)
MPQLNSGGGDELGANDELIRFKDEGEQEEKSPGEGSAEGDLADVKSSLVNESENHSSDSD
SEVERRPPPRETFEKPRDYLSEAFRRQQDAAFFKGPPYAGYPFLMIPDLGGHYLPNGALS
PSARTYLQMKWPLLDSPSTAGLKDARSPSPAHLSNKVPVVQHPHHMHPLTPLITYSNEHF
SPGTPPGHLSPEIDPKTGIPRPPHPSELSPYYPLSPGAVGQIPHPLGWLVPQQGQPMYSI
PPGGFRHPYPALAMNASMSSLVSSRFSPHMVPPPHHGLHTSGIPHPAIVSPIVKQEPSSG
NISPNLITKPSVVVKKEEEKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGR
RWHSLSREEQAKYYELARKERQLHSQLYPTWSARDNYGKRKKRKRDKQSPEMEITKTKKM
CVQHLPADKSCDSPASSHGSMLDSPATPSAALASPAAPAATHSEQAQPLSLTTKPEARAQ
LSLSHSAAFLASKSPPSSSLSGSLSSPVGSPLLSRPIPLTSSILSPPCVFPSALQALPLL
QAQPLSLVTKSSD

>Danio rerio_TCF7L1a(ENSDARP_90035)
MPQLNGGGGDDLGANDELISFKDEGEQEEKISENVSSERDLDEVKSSLVNESENNSSSSD
SEQTDRRPRPRPDLESYEKQREYFAEALRRQQDGGFFKGPPYAGYPFLMIPDITNPYLSN
GSLSPSTRTYLQMKWPLLDVPASAALKDSRSPTPGHLSNKVPVVQHPHHVHPLTPLITYS
NEHFSPGTPPSHLSPEILDPKTGIPRTPHPSELSPYYPLSPGAVGQIPHPLGWLVPQQGQ
HMYSIPPGGFRHPYPALAMNASMSSLVSSRFSPHMVPHPPHGLHQTGIPHPAIVSPAIKQ
EPNGESPSNSTHGKPSVPVKKEEEKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAIN
QILGRRWHSLSREEQAKYYELARKERQLHSQLYPGWSARDNYGKRKKRKRDCKSDSPSES
NFSPQPKKQCVPYLSSEKMCDSPTSSHGSMLDSPATPSAALASPAAPAATHSEQAQPLSL
TTKPEGRAHHNHPHFPLPGKSSGSGSGSSMALHSLSRPIPFTSLPPSLLGPNSPFHQAAL
HSHHALLQTQPLSLVTKSVE

>Danio rerio_TCF7L1b(ENSDARP_51824)
MPQLNGGGGDELGANDEMISFKDEGEQEDKISENVSAERDLDDVKSSLVNESENNSSSSD
SEQTERRPQPRADLESYEKAREYFTEALRRQQDGCFFKSPHYPGYPFLMIPDLANPYLSN
GALSPSARTYLQMKWPLLDVPGSAALKDSQSPSPGHLSNKVPVVQHAHMHPLTPLITYSN
EFPPGTPPAHLSPEILDPKTGIPRTPHPAELSPYYPLSPGAVGQIPHPLGWLVPQQGQHM
YPITAGGFRHPYPALAMNASMSSLVSSRFSPHLVPHHPHGLHQTGIPHPAIVSPVIKQEP
NGELSPPVNTKSPGPNKKDEDKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQIL
GRRWHSLSREEQAKYYELARKERQLHSQLYPGWSARDNYGKRKKRKRDNKTDSTPEDFSM
RSKKPCVQYLPQEKMIDSPGSSHGSMLDSPATPSAALASPAAPAATHSEQAQPLSLTTKP
ERFPLLSKPPPSSSSSSSSSSSGLPTPPLLSRPLPFALLTPPSPFHQAALHSHHALFQSQ
PLSLVTKSSD

>Takifugu rubripes_TCF7L1(ENSTRUP_2635)
MPQLNGGGGDDLGANDEGGGVGVGGGGGGDDLGANDEMISFKDEGEQEEKISENVSAERD
LDDVKSSLVNESESSSDSEQAERRPQTRADSESYDKARDYFSEALRRQQDGGFFKSPHYP
GYPFLMIPDLTNPYLPNGSLSPSARTYLQMKWPLLDVPGSAGLKDSRSPTPGHLSNKVPV
VQHAHHVHPLTPLITYSNEHFSPGTPPSHLSPEILDPKTGIPRTPHPSELSPYYPLSPGA
VGSIAHPLGWFMPQQGQHMYSIPPGGFRHPYPALAMNASMSSLVSSRFSPHMVTPPPHGL
HQTGIPHPAIVSPAIKQEPSGDNISPTMQAKSPAPHKKEEDKKPHIKKPLNAFMLYMKEM
RAKVVAECTLKESAAINQILGRRWHSLSREEQAKYYELARKERQLHSQLYPGWSARDNYG
KRKKRKRENKPDSKPEGQSLEEPEGNFSIRSKKQCVQYLPSEKMCDSPASSHGSMLDSPG
TPSAALASPAAPAATHSEQAQPLSLTTKPEGRMHHRFPLPGKASGSTFGTSGSQPTTPIL
TRPIPFTSLHPSMLSSPSPFHQAALHTHHALYQSQPLSLVTKPTE

>Tetraodon nigroviridis_TCF7L1(ENSTNIP_9036)
MPQLNGGGGDDLGANDEMISFKDEGEQEEKISENVSAERDLDDVKSSLVNESESSSDSEP
SVSKRRGAPEPVADSESYDKARDYFSEALRRQQDGGFFKSPHYPGYPFLMIPDLTNPYLP
NGSLSPSARTVRGGGGSSHFTVARSVRHQAHSRYLQMKWPLLDVPGSAGLKDSRTPTPGH
LQSNKVPVVQHAHHVHPLTPLITYSNEHFSPGTPPSHLSPEILDPKTGIPRTPHPSELSP
YYPLSPGAVGSIAHPLGWFMPQQGQHMYSIPPGGFRHPYPALAMNASMSSRFSPHMVTPP
PHSLHQTGIPHPAIVSPAIKQEPSGDNISPTMQAKSPAPHKKEEDKKPHIKKPLNAFMLY
MKEMRAKVVAECTLKESAAINQILGRRWHSLSREEQAKYYELARKERQLHSQLYPGWSAR
DNYGKRKKRKRENKPDSKPEVSNFFATKCRSFEVTQRFSGFLGNKPTFFLQIYLSTDFSI
RSKKQCVQYLPSEKMCDSPASSHGSMLDSPATPSAALASPAAPAATHSEQAQPLSLTTKP
EGRVHHRFPLPGKASGSIGTSGSQPTTPILTRPIPFTSLHPSMLSSPSPFHQAALHTHHL
FQSQPLSLVTKPTE

>Gasterosteusaculeatus_TCF7L1a(ENSGACP_14801)
MPQLNGGGGDDLGANDEMISFKDEGEQEEKISENVSADRDLDDVKSSLVNESENNSSSSD
SEQAERRPQTRPDSESYEKARDYFNEALRRQQDGGFFKSPHYPGSLFFMFQDLYNPSFSN
VWLSPGERSYLQMKWPILDVPGSAGLKDSRSPTPGHLSNKVPVVQHAHHVHPLTPLITYS
NEHFSPGTPPSHLSPEILDPKTGIPRTPHPSELSPYYPLSPGAVGSIAHPLGWFMQQQGQ
PMYSIPPGGFRHPYPALAMNASMSSLVSSRFSPHMVSPSPHGLHQTGIPHPAIVSPAIKQ
EPSDMSPSMHARKSPVPPKKEEDKRPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQ
ILGRRWHSLSREEQAKYYELARKERQLHSQLYPGWSARDNYGKRKKRKRDNKPDSKPEDF
SIRSKKQCVQYLPSDKMCDSPASSHGSMLDSPATPSAALASPAAPAATHSEQAQPLSLTT
KPEGRMHHHFSLPGKASGSTHLSIPIGTSGSHPTTPILTRPIPFTSLHPSMLSPPSPFHQ
AALHSHHALFQSQPLSLVTKPTE

>Gasterosteusaculeatus_TCF7L1b(ENSGACP_2489)
MPQLSGGDDLGANDELIAFKDEGEQEEKRNASSERDLDDVKSSLVNESESSSDSEADRQS
RANSDLENRIRHNHLFQEALRRQQDGGLFQVSSSPFVGYPFFMIPDLGNFCSPYLSNGAL
APGARTYLPFQWPLLDVPGRAAMRDSAAPANLSNNVSMVQHPHMTHLHPLLSYSPEAFSP
QRASPGFSPDTGMSRSPCYPVSPGGMAQVPHPLGWLPRRQGQAVYPLAGGFSPAALAMNA
SMSSLVSGNFSPRLQTPQSTISHSPFVPSRVKQEPGCSNQNGRSTSDVLQDKDEKKPHIK
KPLNAFMLYMREERPKVVSQCKVKESATINQILGQRWHSLSKDEQTKYYELARKERLVHS
KLYPGWSARDNYGKKKKRKRAKSETLFENTHTQPYTVSHLTHTHLSQASPASSLDSPATP
TTALASPAAPAPTHTEHTHSSSYSGQASPYGEQLQPLALTTKPHRTLHPLSRSTSTPTSS
CDTPTSSPQAPSRCSPPLPPFLVPPPTAAHQALPRCLNCTTCAAYLIVPSAPCSLTQEST
L

>Oryzias latipes_TCF7L1(ENSORLP_14809)
MPQLNGGGGDDLGANDEMIPFKDEGEQEEKISENVSAERDLDDVKSSLVNESENNSSSSD
SEHAERRPQTRPDSESYEKTREYFSEALRRQQDGGFFKSPHYPGYPFLMIPDLTNPYLSN
GSLSPGARTYLHMKWPLLDVPSSAGIKDSRSPTPGHLIFISNKVPVVQHGHHVHPLTPLI
TYSNNEHFSPGTPPSHLSPEILDPKTGIPRTPHPSELSPYYPLSPGAVGSIAHPLSWFMQ
HQGQPMYSIPPGGFRHPYPALAMNASMSSRFSPHMVTPPPHSLHQTGIPHPAIVSPAIKQ
EPSGDNISPSMHARKSPVPAKKEEDKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAI
NQILGRRWHSLSREEQAKYYELARKERQLHSQLYPGWSARDNYGKRKKRKRENKPDSKPE
ALHRQLILSFTSTYPCFSVLLYFDKQLMKFSASNGRYVCGYFSIRSKKQCVQYLPSEKMC
DSPTSSHGSMLDSPATPSAALASPAAPAATHSEQAQPLSLTTKPEGRMHHHFSLPEPAVS
IPSGTSGSQSSTPILTRPIPFTSLHPSMLSPPSPFHQAALHSHHSLFQSQPLSLVTKPTE

>Branchiostoma floridae_(AAZ77711)
MPQLNGSGGDDLGAGDETISFKDEGEQEEKSAENVSNDLSDIKSSLANESESSQSGAVPSEGSKPPLQSY
PREDSRRGDEGSKAESVPVVSRGPAYLTPGGVIVSNMGVYPHPNGSLAASATSNKVSVVHGPPHPGPLTQ
LMMYSNEHFAPGTPPHIGVPPNSIEVDPKTGIPRPRHPADLPPMYAIPPNQLPQLGPSYPKIEEYHSQAL
WQSQGVYPISAAGYRHPYPTAIAVNATNMPRYPVLQHPHHPGMPPTGIPHPAIVSPHGMNLKHDPSQMHQ
KQDQKKEPEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALPREEQAKYYELARK
ERQLHMQLYPGWSARDNYGKKKKRKRDKQQGDTSEVSNPKRCRARFGLDQQQAWCKPCRYGADEWRESPI
LFCFCLPVWNGGFKAQALPNGSVV

>Strongylocentrotus purpuratus_(NP_999640)
MPQQHSRGGEDDGPPDETKTYHTEGEQEEKASENVVGPRDSFDHLNDVKSSLIDEGESVSQKGSSSQRNK
RLSSGYGDHSKEDRHKKLHSVSDGSKLDHIARFTPYSSLAFIANAGYPNGSMVGGPGITPKCGVPNVFPS
PLRLGEGQKMPVLHPGAYPPSLAQLMMYQQEHYSHSPGTPPPHVRGLEVDSKTGILRRSHSEISPYHPLS
PSSLGTHPLEVYNMSWPGQPFYPLTSSALRSPYPSSLAVSPASMARLGPSPIGAGPIPVGSLPHFLMHPI
GSSQQHDAQQQSNDRHQKEKEKKLAAQEAKNKQQHIKKPLNAFMLYMKEMRASVVKECTLKESAAINQIL
GRRWHALTREEQAKYYELARKERQLHMQLYPGWSARDNYAIHGKKKKKKRDKSHGDNPGEPSTPKKCRAR
FGVDQQDFWCKPCRRKKKCIRYISSDENDHGRNDDDMDDDDSSLSRRKSWLKHGGTQH