>Homo sapiens_HTRA2(ENSP_258080)
MAAPRAGRGAGWSLRAWRALGGIRWGRRPRLTPDLRALLTSGTSDPRARVTYGTPSLWAR
LSVGVTEPRACLTSGTPGPRAQLTAVTPDTRTREASENSGTRSRAWLAVALGAGGAVLLL
LWGGGRGPPAVLAAVPSPPPASPRSQYNFIADVVEKTAPAVVYIEILDRHPFLGREVPIS
NGSGFVVAADGLIVTNAHVVADRRRVRVRLLSGDTYEAVVTAVDPVADIATLRIQTKEPL
PTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAA
IDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSSSGISGSQRR
YIGVMMLTLSPSILAELQLREPSFPDVQHGVLIHKVILGSPAHRAGLRPGDVILAIGEQM
VQNAEDVYEAVRTQSQLAVQIRRGRETLTLYVTPEVTE

>Gorilla gorilla_HTRA2(ENSGGOP_6190)
MAAPRAGRGAGWSLRAWRALGGIRWGRRPRLTPDLRALLTSGTSDPRARVTYGTPSLWAR
LSVRVTEPRACLTSGTPGPRAQLTAVTPDTRTQEASENSGTRSRAWLAVALGAGGAVLLL
LWGGGRGPPAVLAAVPGPPPASPRSQYNFIADVVEKTAPAVVYIEILDRHPFLGREVPIS
NGSGFVVAADGLIVTNAHVVADRRRVRVRLLSGDTYEAVVTAVDPVADIATLRIQTKEPL
PTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAA
IDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSSSGISGSQRR
YIGVMMLTLSPSILAELQLREPSFPDVQHGVLIHKVILGSPAHRAGLRPGDVILAIGEQM
VQNAEDVYEAVRTQSQLAVQIRRGRETLTLYVTPEVTE

>Macaca mulatta_HTRA2(ENSMMUP_2846)
MAAPRAGRGAGWSLRAWRALGGIRWGRRPRLTPDLRALLTSGTSDPRARVTYGTPSLWAR
LCVGVPEPRACLTSGTPGPRAQLTAVTPDTRTREASENSGTRSRAWLAVALGAGGAVLLL
LWGGGRGPPAVLAAVPGPPPASPRSQYNFIADVVEKTAPAVVYIEILDRHPFLGREVPIS
NGSGFVVAADGLIVTNAHVVADRRRVRVRLLSGDTYEAVVTAVDPVADIATLRIQTKEPL
PTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAA
IDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSSSGISGSQRR
YIGVMMLTLSPSILAELQLREPSFPDVQHGVLIHKVILGSPAHRAGLRPGDVILAIGGQM
VQNAEDVYEAVRTQSQLAVQIRRGRETLTLYVTPEVTE

>Mus musculus_HTRA2(ENSMUSP_87073)
MAALKAGRGANWSLRAWRALGGIFWRKPPLLAPDLRALLTSGTPDSQIWMTYGTPSLPAQ
VPEGFLASRADLTSRTPDLWARLNVGTSGSSDQEARRSPGSRRREWLAVAVGAGGAVVLL
LWGWGRGLSTVLAAVPAPPPTSPRSQYNFIADVVEKTAPAVVYIEILDRHPFSGREVPIS
NGSGFVVASDGLIVTNAHVVADRRRVRVRLPSGDTYEAMVTAVDPVADIATLRIQTKEPL
PTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQNNVEYIQTDAA
IDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSWFGTSGSQRR
YIGVMMLTLTPSILIELQLREPSFPDVQHGVLIHKVILGSPAHRAGLRPGDVILAIGEKL
AQNAEDVYEAVRTQSQLAVRIRRGSETLTLYVTPEVTE

>Rattus norvegicus_HTRA2(ENSRNOP_30076)
MAALKAGRGANWSLRAWRALGGIFWRKGPLLAPDLRALLTSGTPDPQARMTYGTPSLPAR
VPLGVLASRANLTSGTPDLWVRLTVGTPGSSDQEDCGSPGSRRREWLAVALGAGGAVLLL
LWGWGRGPSTVLAAVPAPPPTSPRSQYNFIADVVEKTAPAVVYIEILDRHPFSGREVPIS
NGSGFIVASDGLIVTNAHVVADRRRVRVRLPSGDTYEAMVTAVDPVADIATLRIQTKEPL
PTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAA
IDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSWFGISGSQRR
YIGVMMLTLTPSILAELQLREPSFPDVQHGVLIHKVILGSPAHRAGLRPADVILAIGEKM
IQNAEDVYEAVRTQSQLAVRIRRGPETLTLYVTPEVTE

>Oryctolagus cuniculus_HTRA2(ENSOCUP_13232)
MAALRAGRGAGWSLWGLRALGGIRWGKGPLLTSDLRALLTSGTPDLRARMTYGTPSLRAR
LAVGVPEPRAFLTSGSPDPRPRLTAGAPDSRPREASGTPGTRPRVWLAVALGAGGAVLLL
LWGGGRGPPAVLASVPAPPPTSPRSQYNFIADVVEKTAPAVVYIEILDRHPFSGREVPIS
NGSGFVVAADGLIVTNAHVVADRRRVRVRLPSGDTYEAMVTAVDPVADIATLRIQTKEPL
PTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAA
IDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSWFGISGSQRR
YIGVMMLTLTPSILAELQLREPSFPDVQHGVLIHKVILGSPAHRAGLRPGDVILAIGEQL
VQNAEDVYEAVRTQSQLAVRIRRGSETLTLYVTPEVTE

>Canis familiaris_HTRA2(ENSCAFP_12325)
MAALRAGRGAAWNLRGWRALGGVHSGKGPLLTPDLRALLTSGIPDPRARVTYGTPSLRAR
WSVGVPEPRTCLTSRTSDSRAWLAVGTPDPRTQEGSGTPGTRPRIWLAVALGAGGAVLLL
LWGGGRGPPAVLASVLGSPPSSPRSQYNFIADVVEKTAPAVVYIEILGRHPFSGREVPIS
NGSGFVVAADGLIVTNAHVVADRRRVRVRLLSGDTYEAVVTAVDPVADIATLRIQTKEPL
PTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAA
IDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSWFGISGSQRR
YIGVMMLTLTPSILAELQLREPSFPDVQHGVLIHKVILDSPAHRAGLRPGDVILAIGEQL
VQNAEDIYEAVRTQSQLAVRIRRGPETLTLYVTPEVTE

>Felis catus_HTRA2(ENSFCAP_6637)
MAALRAGRGAGWNLWGWRALGGVPWGKGPLLTPDLRALLTSGTPDPRARVTYGTPSLWAR
LSGGVPEPRTCLTSGTSDSRARLTAGSPDLKTREVSETPGTRPRIWLAVALGAGGAVLLL
LWGGGRGPPAVLASVLGSPPTSPRSQYNFIADVVEKTAPAVVYIEILGRHPFSGREVPIS
NGSGFVVAADGLIVTNAHVVADRRRVRVRLLSGDTYEAMVTAVDPVADIATLRIQTKEPL
PTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAA
IDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSWFGISGSQRR
YIGVMMLTLTPSILAELQLREPSFPDVQHGVLIHKVILDSPAHRAGLRPGDVILAIGEQL
VQNAEDIYEAVRTQSQLAVRIRRGPETLTLYVTPEVTE

>Bos taurus_HTRA2(ENSBTAP_26804)
MAALRAGRGAGWSLRGWRALWGGRWGKGPLLTPDLRALLTSGTPDPRTRVTYGTPSFRAR
LSVGVPEPRTCLRSRTSDLRARLIAGTPDPRTPEDSGTPGTRLRVWLAVALGAGGAVLLL
FWGGGRGPPAVLASVLGSPPTSPRSQYNFIADVVEKTAPAVVYIEILGRHPFSGREVPIS
NGSGFVVAADGLIVTNAHVVADRRRVRVRLPSGDTYEAVVTAVDPVADIATLRIQTKEPL
PTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPAKDLGLPQTNVEYIQTDAA
IDFGNSGGPLVNLDGEVIGVNTMKVTSGISFAIPSDRLREFLHRGEKKNSWFGISGSQRR
YIGVMMLTLTPSILAELQLREPSFPDVQHGVLIHKVILDSPAHRAGLRPGDVILAIGEQL
VQNAEDIYEAVRTQSQLAVRIRRGQETLTLYVTPEVTE

>Equus caballus_HTRA2(ENSECAP_520)
MAALRAGQGAGWSLRGWRALGGVRWGKGPLLTPDLRALLTSGTSDPRARVTHGTPSLQAR
LSGGVPEQRTCLTSGTSDSRAQLTGGNPDPRTREDSGTPGTRPRVWLAVALGAGGAVLLL
LWGGGRGPPAVLASVLGSPPTSPRSQYNFIADVVEKTAPAVVYIEILGRHPFSGREVPIS
NGSGFVVAADGLIVTNAHVVADRRRVRVRLPSGDTYEAVVTAVDPVADIATLRIQTKEPL
PTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAA
IDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSSLGISGSQRR
YIGVMMLTLTPSILAELQLREPSFPDVQHGVLIHKVILDSPAHRAGLRPGDVILAIGEQL
VQNAEDIYEAVRTQSQLAVRIRRGPETLTLYVTPEVTE

>Anolis carolinensis_HTRA2(ENSACAP_8508)
SPPPPRWRWAAMGACGAGAGLLLLLFFPRKPAEARPPVPSPPPSPRSTYNFIADVVERTA
PALVYIEILGRHPFSGREVPISNGSGFVVSSDGLIVTNAHVVANRRRVRVRLASGELYDA
TVRLVDQVADIATLKISPKKPLPTLRLGRSSEVRQGEFVVAMGSPFALQNTITSGIVSSA
QRGGRELGLSSSDIEYIQTDAAIDFGNSGGPLVNLDGEVIGVNTMKVTPGISFAIPSDRL
RAFLEKEEKSKDSWFGGKKEGKRRYIGVMMLTLTSSILSELKMRDPSFPDISYGVLIHKV
IIGSPAHQAGLKAGDVVVEINGRASRRAEDVYEAVRTQDHLTLLVHRGYEALLLTITPEV
TE

>Danio rerio_HTRA2a(ENSDARP_92827)
MATSHVNRCLLRTITRCHRDSSRQLNLTTVRALGHFSNFSSGKEEHVETVDPPRGSGGGS
GTSRLAVALGLGLGGAAAVFSLRGEDNKDALQRTVAVKNLLIDSILPTVQCASPFKPDSP
RYKYNFIADVVEKSTPAVVYIEIVGRHPFSGREVPISNGSGFIVSSDGLIVTNAHVVANK
RGVRVKLTNGETYNATVQDVDQAADIATIKINVKNPLPTLRLGKSSDVRQGEFVVAMGSP
FSLKNTITSGIVSSAQRGSKELGLSNSNMDYIQTDATIDFGNSGGPLINLDGEVIGINTM
KVTAGISFAIPSDRVRLFLDRSADKQNSWFGESGWKRRYIGVMMLTLTPRHPFSGREVPI
SNGSGFIISSDGLIVTNGHVVANKCGVRVKLTNDETYNATVQDVDQAADIASIKINVKNP
LPTLRLGKSSDVRQGEFVVAMGSPFSLKNTITSGIVSSAQRGSKELGLSNSNMDYIQTDA
TIDFGNSGGPLINLDGEVIGINTMKVTAGISFAIPLFLDRSADKQKSWFGESESKRRYIG
VMMLTLTPSIIKELRMRDPSFPDVSHGVLIHRVIVGSPANRAGMKPGDVIIEINGVKVNT
SEEIYNAVRTSESLNVVVRRGADLLMLHMTPESTE

>Danio rerio_HTRA2(ENSDARP_101935)
LFRHPFSGREVPISNGSGFIISSDGLIVTNAHAVANKRGVRVKLTNGETYNATVQDVDQA
ADIATIKINVKNPLPTLRLGKSSDVRQGEFVVAMGSPFSLKNTITSGIVSSAQRGSKELG
LSNSNMDYIQTDATIDFGNSGGPLIHLDGEVISINTMKVTAGISFAIPSDRVRLFLDRSA
DKQNSWFGESGSKRRYIGVMMLTLTPSIIDELRMRDPSFPDVSHGVLIHRVIVGSPANRA
GMKPGDVIIEINGVKVNTSEEIYNAVRTSESLNVVVRRGADLLMLHMTPESTER

>Takifugu rubripes_HTRA2a(ENSTRUP_31408)
PDSPRYKYNFIADVVEKSTPAVVYIEILGRHPFSGREVTVSNGSGFLISTDGLIVTNAHV
VANKRGVRVKLNNGEMYNATVQDVDQVADIATIKISVKNPLPTLPLGCSAQVRQGEFVVA
MGSPFALRNTITSGIVSSAQRGSKELGLSNTNMDYIQTDAAIDFGNSGGPLINLDGEVIG
INTMKVTAGISFAIPSDRLRLFLDRAEQKKSSWFRDSDTRRRYIGVMMLTLTPSIIAELK
LRDPSFPEVTHGVLIHRVIMGSPANRAGMIPGDIVVEINGAKANTSEEVYEAVRSSDHIS
MLVQRGGELLQLRVTPEYTE

>Takifugu rubripes_HTRA2b(ENSTRUP_18942)
MRLWVVLCATVLLAAEARIVKRLAIGCPDKCDKSQCAPVPADCLAGDVLDRCDCCPVCGA
GDGEQCGGTDDRECAEGLECLVTDGVEVSATVRRRGTAGMCVCTSSQPVCGSDGVSYRNI
CELKRVSNMAVKMQRPPVIFIQRGACGEGQQNPDSLRYKYNFIADVVEKIGPAVVHIELY
RKMMFTKRELAVASGSGFVVSEDGLIVTNAHVVANKHRVKVELKSGATFDAKVRDIDEKA
DIALIKIDAPTKLPVLLLGRSADLRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGL
RNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDKIRQFLAESHD
RQSESNGRFQHFHPFPSSGQTTTQKKFIGIRMLSITPTLAKELKEKQPDFPDVTSGVYVI
EVISRTPAARAGLQDKDVIISINGEQISSSSDVSEIIKTGSVLRTVVRRGNEDVILTIIP
EEMEP

>Gasterosteusaculeatus_HTRA2(ENSGACP_11279)
PDSPRFKYNFIADVVEKSTPAVVYIEIVGRHPFSGREVPVSNGSGFIISSDGLIVTNAHV
VANKKGVRVKLTNGETYNATVKDVDPVADIATIKISAKSPLPTLALGRSSDVRQGEFVVA
MGSPFSLRNTITSGIVSSVQRGSKELGLSNSNMDYIQTDAAIDFGNSGGPLINLDGEVIG
INTMKVTPGISFAIPSDRLTLFLDQAAKKKNSRSGESATKRRYIGVMMLTLTPSIISELK
LRDRSFPDVAYGILIHRVILGSPADRAGMLPGDVVVEINGVKVNTSEEIYQAVRSGDKIT
TVVQRGHQLLRLQITPESTEP

>Oryzias latipes_HTRA2(ENSORLP_19645)
MAVSAAVRKCFVSALVTQARCQRLNALPKNTFSRASSAVTCGHGEPTGRKSLYDRAEAEG
DSGQSGGSVLWTSLGLGLCGAAFLDSQKDKGVRGDSKSRRFLELLLPSAHCASPFKPDSP
RFKYNFIADVVEKSTPAVVYIEILGRHPFSGREVPVSNGSGFIISSDGLIVTNAHVVANK
RGVRVKLTNGDMYHASVQDVDPVADIATIKITTKDVQNPLPIETGQSSDIRQGEFVVAMG
SPFALRNTITSGIVSSAQRDSKELGLSNPNMEYIQTDATIDFGNSGGPLINLDGEVIGIN
TMKVTAGISFAIPSDRLKIFLDQAAKKTKSSVGESRTKARYIGVMMLTLTPSIITELQLR
DPMFPNVTHGILIHRVIIGSPASRAGMLAGDIVVEINGVKVNTSEEIYKAVRSSDRITML
VQRGKELLRLQVTPEFIDP>Homo sapiens_HTRA1(ENSP_357980)
MQIPRAALLPLLLLLLAAPASAQLSRAGRSAPLAAGCPDRCEPARCPPQPEHCEGGRARD
ACGCCEVCGAPEGAACGLQEGPCGEGLQCVVPFGVPASATVRRRAQAGLCVCASSEPVCG
SDANTYANLCQLRAASRRSERLHRPPVIVLQRGACGQGQEDPNSLRHKYNFIADVVEKIA
PAVVHIELFRKLPFSKREVPVASGSGFIVSEDGLIVTNAHVVTNKHRVKVELKNGATYEA
KIKDVDEKADIALIKIDHQGKLPVLLLGRSSELRPGEFVVAIGSPFSLQNTVTTGIVSTT
QRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDKI
KKFLTESHDRQAKGKAITKKKYIGIRMMSLTSSKAKELKDRHRDFPDVISGAYIIEVIPD
TPAEAGGLKENDVIISINGQSVVSANDVSDVIKRESTLNMVVRRGNEDIMITVIPEEIDP

>Pan troglodytes_HTRA1(ENSPTRP_5327)
QEDPNSLRHKYNFIADVVEKIAPAVVHIELFRKLPFSKREVPVASGSGFIVSEDGLIVTN
AHVVTNKHRVKVELKNGATYEAKIKDVDEKADIALIKIDHQGKLPVLLLGRSSELRPGEF
VVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGE
VIGINTLKVTAGISFAIPSDKIKKFLTESHDRQAKGKAITKKKYIGIRMMSLTSSKAKEL
KDRHRDFPDVISGAYIIEVIPDTPAEAGGLKENDVIISINGQSVVSANDVSDVIKRESTL
NMVVRRGNEDIMITVIPEEIDP

>Gorilla gorilla_HTRA1(ENSGGOP_4758)
MQIPRAALLPLLLLLLLAAPASAQLSRAGRSAPLAAGCPDRCEPARCPPQPQHCEGGRAR
DACGCCEVCGAPEGAACGLQEGPCGEGLQCVVPFGVPASATVRRRAQAGLCVCASSEPVC
GSDANTYANLCQLRAASRRSERLQLPPVIVLQRGACGQGQEDPNSLRHKYNFIADVVEKI
APAVVHIELFRKLPFSKREVPVASGSGFIVSEDGLIVTNAHVVTNKHRVKVELKNGATYE
AKIKDVDEKADIALIKIDHQGKLPVLLLGRSSELRPGEFVVAIGSPFSLQNTVTTGIVST
TQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDK
IKKFLTESHDRQAKGKAITKKKYIGIRMMSLTSSKAKELKDRHRDFPDVISGAYIIEVIP
DTPAEAGGLKENDVIISINGQSVVSANDVSDVIKRESTLNMVVRRGNEDIMITVIPEEID
P

>Macaca mulatta_HTRA1(ENSMMUP_11963)
MQIPRAALLPLLLLLLLAAPASAQLSRAGRSAPLATGCPERCEPARCPPQPEHCEGGRAR
DACGCCEVCGAPEGAACGLQEGPCGEGLQCVVPFGVPASATVRRRAQAGLCVCASNEPVC
GSDANTYANLCQLRAASRRSERLHRPPVIVLQRGACGQGQEDPNSLRHKYNFIADVVEKI
APAVVHIELFRKLPFSKREVPVASGSGFIVSEDGLIVTNAHVVTNKHRVKVELKNGATYE
AKIKDVDEKADIALIKIDHQGKLPVLLLGRSSELRPGEFVVAIGSPFSLQNTVTTGIVST
TQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDK
IKKFLTESHDRQAKGKAITKKKYIGIRMMSLTSSKAKELKDRHRDFPDVISGAYIIEVIP
DTPAEAGGLKENDVIISINGQSVVSANDVSDVIKRESTLNMVVRRGNEDIMITVIPEEID
P

>Mus musculus_HTRA1(ENSMUSP_6367)
MQSLRTTLLSLLLLLLAAPSLALPSGTGRSAPAATVCPEHCDPTRCAPPPTDCEGGRVRD
ACGCCEVCGALEGAACGLQEGPCGEGLQCVVPFGVPASATVRRRAQAGLCVCASSEPVCG
SDAKTYTNLCQLRAASRRSEKLRQPPVIVLQRGACGQGQEDPNSLRHKYNFIADVVEKIA
PAVVHIELYRKLPFSKREVPVASGSGFIVSEDGLIVTNAHVVTNKNRVKVELKNGATYEA
KIKDVDEKADIALIKIDHQGKLPVLLLGRSSELRPGEFVVAIGSPFSLQNTVTTGIVSTT
QRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDKI
KKFLTESHDRQAKGKAVTKKKYIGIRMMSLTSSKAKELKDRHRDFPDVLSGAYIIEVIPD
TPAEAGGLKENDVIISINGQSVVTANDVSDVIKKENTLNMVVRRGNEDIVITVIPEEIDP

>Rattus norvegicus_HTRA1(ENSRNOP_27860)
MQFLRTALLSLLLLLLAAPSLALPSGISRSAPAATVCPEHCDPTRCAPPPTDCEGGRVRD
ACGCCEVCGALEGAVCGLQEGPCGEGLQCVVPFGVPASATVRRRAQAGLCVCASSEPVCG
SDAKTYTNLCQLRAASRRSEKLRQPPVIVLQRGACGQGQEDPNSLRHKYNFIADVVEKIA
PAVVHIELYRKLPFSKREVPVASGSGFIVSEDGLIVTNAHVVTNKNRVKVELKNGATYEA
KIKDVDEKADIALIKIDHQGKLPVLLLGRSSELRPGEFVVAIGSPFSLQNTVTTGIVSTT
QRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDKI
KKFLTESHDRQAKGKTVTKKKYIGIRMMSLTSSKAKELKDRHRDFPDVISGAYIIEVIPD
TPAEAGGLKENDVIISINGQSVVTANDVSDVIKKENTLNMVVRRGNEDIVITVVPEEIDP

>Felis catus_HTRA1(ENSFCAP_3371)
HRPYLGLVMDGFAGQWQEDPNSLRHKYNFIADVVEKIAPAVVHIELFRKLPFSKREVPVA
SGSGFIVSEDGLIVTNAHVVTNKHRVKVELKNGATYEAKIKDVDEKADIALIKIDHEGKL
PVLLLGRSSELRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAI
INYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDKIKKFLTESHDRQAKGKAITKKKY
IGIRMMSLTSSKAKELKDRHRDFPDVLSGAYIIEVIPDTPAEAGGLKENDVIISINGQSV
VSANDVSDVIKKESTLNMVVRRGNEDIMITVIPEEIDP

>Equus caballus_HTRA1(ENSECAP_7959)
GQEDPNSLRHKYNFIADVVEKIAPAVVHIELFRKLPFSKREVPVASGSGFIVSEDGLIVT
NAHVVTNKHRVKVELKNGATYEAKIKDVDEKADIALIKIDHEGNLPVLLLGRSSELRPGE
FVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDG
EVIGINTLKVTAGISFAIPSDKIKKFLTESHDRQAKGKAITKKKYIGIRMMSLTSSKAKE
LKDRHRDFPDVLSGAYIIEVIPDTPAEAGGLKENDVIISINGQSVVSANDVSDVIKKEST
LNMVVRRGNEDIMITVIPEEIDP

>Gallus gallus_HTRA1(ENSGALP_25070)
XRRAERLRQPPIIAIQRGGCGQGQEHPNSLRHKYNFIADVVEKIAPAVVHIELFRKLPYS
KREIPVASGSGFIVSEDGLIVTNAHVVTNKNRVKVELKNGETYEAKIKDVDEKADIALIK
IDAQGKLPVLLLGQSGDLRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMD
YIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDKIKKFLTESHDRQAKGK
AITKKKYIGIRMMSLTPSKAGELKDRHKDFPDVVSGAYVIDVIPETPAEAGGLKDNDVII
SINGQSITSASDVSDIIKKDSTLNMVVRRGNEDVMLTVIPEEIDP

>Taeniopygia guttata_HTRA1(ENSTGUP_11678)
SALPACPERCDRSRCPALPAGCPGGPVPDACGCCRVCGAEEGEACGGAGPPCGEGLQCVL
PPGAVPASATVRKRAAAGRCQCTSSEPVCGSDAVTYASHCQLRAASRRAESLRQPPIIAI
QRGACGQGQEHPNSLRHKYNFIADVVEKIAPAVVHIELFRKLPFSKREVPVASGSGFIVS
EDGLIVTNAHVVTNKNRVKVELKNGETYEAKIKDVDEKSDIALIKIDSQGKLPVLLLGQS
ADLRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNSGG
PLVNLDGEVIGINTLKVTAGISFAIPSDKIKKFLTESHDRQAKGKAVTKKKYIGIRMMSL
TPSKARELKDRHKDFPDVVSGAYVIEVIPETPAEAGGLKDNDVIISINGQSISSASDVSD
IIKKDSTLHMVVRRGNEDVMLTIVPEEIDP

>Danio rerio_HTRA1a(ENSDARP_20528)
MRLLILCASIILVPLLCDARIIKRYVIGCPERCDKSLCPPIPPDCLAGDILDQCDCCPVC
AAGEGESCGGTGKLGDPECGEGLECAVSDGVGATTTVRRRGKTGVCVCKSSEPVCGSDGV
SYRNICELKRVSNRAQKLQQPPIIFIQRGACGKGHEENPDSLRHRYNFIADVVEKIAPAV
VHIELFRKNVFNREVAVASGSGFVVSEDGLIVTNAHVVANKHRVKVELKTGTTYDAKIKD
VDEKADIALIKIDAPMKLPVLLLGRSADLRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGG
KELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDKIRQFL
AESHDRQAKGKTATKKKYIGVRMMTLTPTLAKELKQRKNDFPDVTSGAYVIEVIPKTPAE
VGGLKESDVIISINGQRITSASDVSTAIKTDESLRAVVRRGNEDIILTIIPEEIDP

>Danio rerio_HTRA1b(ENSDARP_48135)
MILVTLFCICALVTSLQADARLSKRYVIGGCPSHCDKSMCPTMPKDCSTGQVMDHCNCCL
VCASGEGEACGGVGKLGDPVCGESLECSVTGGVSYSATVRRRGKQGVCVCKSSDPVCGSD
GVSYRDICELKRVSNRAQSLQQPPVLFIQRGACGTSLHDNPNSLRYKYNFIADVVEKIAP
AVVHIELYRKMVYSKREMAVASGSGFVVSDDGLIVTNAHVVANKNRVKVELKNGASYDAK
IKDVDEKADIALIKIDLPNKLPVLLLGRSADLRPGEFVVAIGSPFSLQNTVTTGIVSTTQ
RGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDKIR
QFLAESYDRLARGRGTTKKRYIGVRMMTLTPSLSKELKGRLRDFPDITSGAYVIEVISKT
PAAAGGLKEHDVIISINGQRISTATDVSAIIKKESSLRVVVRRGNEDIILTIIPMEIDP

>Takifugu rubripes_HTRA1(ENSTRUP_15159)
MFFMQLYMFWSLSLCVIAAFAPVPAYAQSSNRFVVGCPSRCDKSMCPRPPADCAAGQTLD
VCNCCPVCASGEGEACGSNGKLGDPVCGEGLECSVTGGVAYTITVRRRSKSGTCMCKSSE
PVCGSDGVSYRNICELKRVSRRAQKLQQPPVLFIQRGACGKAQNNPESPRHKYNFIADVV
ERIAPSVVHIELFRKMTYSKREVPVASGSGFVVSEDGQIVTNAHVVANKHRVKVELKSGG
SYDAKIKDVDEKSDIALIKIDTPVKLPVLLLGRSSDLRPGEFVVAIGSPFSLQNTVTTGI
VSTTQRGGRELGLRNSDMEYIQTDAIINYGNSGGPLINLDGEVIGINTLKVTAGISFAIP
SDKIREFLAESYDRQSRGRTTAKKKYIGVRMMTLTPALSKELKTQHRDFPDITSGAYVME
VIAKTPAAIGGLKEHDVIISINGQRISSASDVSTAIKKDNKLSIVVRRGNEDLILTVVPV
EIDP

>Tetraodon nigroviridis_HTRA1a(ENSTNIP_14844)
RLISESFHSPIMRLGLLLCALAMLVAEARIVKRLAIGCPEKCDKSQCAPIPADCLAGDAL
DRCDCCPVCASGEGEQCGGSGDRDCAEGMECLVADGVEVSATVRKRGAAGLCVCTSSEPV
CGSDGVSYRNICELKRVSNRAVKLQRPPVILIQRGACGEGQQNPDSLRYKYNFIADVVEK
IAPAVVHIELYRKTIFTKREVAVASGSGFVVSEDGLIVTNAHVVANKHRVKVELKSGATF
DAKIRDVDEKADIALIKIDAPMKLPVLLLGRSADLRPGEFVVAIGSPFSLQNTVTTGIVS
TTQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSD
KIRQFLAESHDRQARGQTVQKKKYIGIRMMSLTPTLAKDLKERQSDFPDVTSGVYVIEVI
SRTPAERAGLHEKDVIISINGEPISLASDVSDAIKGGDALRMVVRRGNEDVILTVVPEEI
DP

>Tetraodon nigroviridis_HTRA1b(ENSTNIP_20138)
VAQLPSANMFWWLSLCAVAALAEAQSSGRFVVGCPARCDKSTCPRPPADCAAGQTLDACR
CCPVCASGEGEACGGTGKLGDPVCGDGLECSVPGGVAHSGTVRRRSRSGTCTCKASEPVC
GSDGVSYRNTCELRRASRRAQRLLQPPVLFVQRGACGKAQDNPDSPRHKYNFIADVVEKI
APSVVHIELFRKMTYSKREVPVASGSGFVVSEDGQIVTNAHVVANKHRVKVELQSGGSYD
AKIQDVDERSDIALIKIAAPTKLPVLLLGRSSDLRPGEFVVAIGSPFSLQNTVTTGIVST
TQRGGRELGLQNSDMDYIQTDAIINYGNSGGPLINLDGEVVGINTLKVTAGISFAIPSDK
IREFLAESYDRQSRGRTAAKKKYIGVRMMTLTPALAKELKTQHRDFPDITSGAYVMEVIA
KTPAAVGGLKEHDVIISINGQRISSASDVSAAIKKDNKLSVVVRRGNEDLILTVVPVEID
P

>Gasterosteusaculeatus_HTRA1a(ENSGACP_18915)
MSLRLVLCVMALLVRPPPAAGARRAKRFAIGCPEKCDVSVCAPIPADCPAGDALDHCDCC
PVCASGEGEQCGGTARRECAEGMECAVTGGVEASATVRRRGAAGVCSCTSSDPACGSDGV
SYRNICELKRVSNRAMKLRQPPVIFIQRGTCGQGQQNPDSLRLKYNFIADVVQKIAPAVV
HIELYRKMMFSKREVAVASGSGFVVSEDGLIVTNAHVVANKHRVKVELKSGATFDARIKD
VDEKADIAVIEIDAPMKLPVLLLGRSADLRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGG
KELGLRNSDIDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVAAGISFAIPSDKIRQFL
VESHARQAKGKTYQKNKYVGVRMMSLTPALTKELKEKQSDFPDITSGAYVIEVIGRTPAE
AAGLQEKDVIISINGEPIASASDVSAAIRRDDTLRTVVRRGNEDVLLSIVPEEIEP

>Gasterosteusaculeatus_HTRA1b(ENSGACP_13658)
MPAHCPAGQILDACHCCQVCASGEGEACGGLGKLGDPVCGEGLECSVSAGVAYTTTVRRR
SKSGTCACKSAEPVCGSDGVSYRNVCELKRVSRRAQKLQQPPVVLIQRGACGKARDNPDS
PRHKYNFIADVVEKIAPSVVHIELFRKMTYSKREVAVASGSGFVVAEDGQIVTNAHVVAN
KHRVKVELKSGGTYDAKIKDVDEKSDIALIKIDVPTKLPVLPLGRSSNLRPGEFVVAIGS
PFSLQNTVTTGIVSTTQRGGRELGLRNSDMEYIQTDAIINYGNSGGPLVNLDGEVIGINT
LKVTAGISFAIPSDKIREFLAEAYDRLSRGRAAAKKKYIGVRMMTLTPSLAKELKTRHLD
FPDITSGAYVMEVIAKTPAAVAGLKEHDVIISVNGQRISSATDVSAAVKRDGSLRVVVRR
GNEDAILTVVPMEIDP

>Oryzias latipes_HTRA1(ENSORLP_18769)
MQLRLPVCVTALFASSWLLAEAQIVKRAAIGCPERCDRSACAPVLQDCLSGDELDRCGCC
PVCASGEGAPCGAPGDQECVEGMECVVTDGVEASATVRRRARAGVCTCISTDPVCGSDGV
SYRNVCELKRVSSRATELQQPPVIFIQRGACGKGQQSPDSLRYKYNFIADVVEKIAPAVV
HIELFRKMVFSKREVSVASGSGFVVSEDGLIVTNAHVVANKHRVKVELKSGATYDAKIKD
IDEKADIALIKIDTPNKLPVLLLGRSADLRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGG
KELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDKILQFL
AESHDRQAKGKTLAKKKYIGVRMMSLTPTLAKELKARHPDFPDLTSGAYVMEVIGRTPAE
AAGLKERDVIISINGEHITSANDVSTTIKREQNLRMVVRRGNEDVMLTVIPEEIDP

>Homo sapiens_HTRA2(ENSP_258080)
MAAPRAGRGAGWSLRAWRALGGIRWGRRPRLTPDLRALLTSGTSDPRARVTYGTPSLWAR
LSVGVTEPRACLTSGTPGPRAQLTAVTPDTRTREASENSGTRSRAWLAVALGAGGAVLLL
LWGGGRGPPAVLAAVPSPPPASPRSQYNFIADVVEKTAPAVVYIEILDRHPFLGREVPIS
NGSGFVVAADGLIVTNAHVVADRRRVRVRLLSGDTYEAVVTAVDPVADIATLRIQTKEPL
PTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAA
IDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSSSGISGSQRR
YIGVMMLTLSPSILAELQLREPSFPDVQHGVLIHKVILGSPAHRAGLRPGDVILAIGEQM
VQNAEDVYEAVRTQSQLAVQIRRGRETLTLYVTPEVTE

>Gorilla gorilla_HTRA2(ENSGGOP_6190)
MAAPRAGRGAGWSLRAWRALGGIRWGRRPRLTPDLRALLTSGTSDPRARVTYGTPSLWAR
LSVRVTEPRACLTSGTPGPRAQLTAVTPDTRTQEASENSGTRSRAWLAVALGAGGAVLLL
LWGGGRGPPAVLAAVPGPPPASPRSQYNFIADVVEKTAPAVVYIEILDRHPFLGREVPIS
NGSGFVVAADGLIVTNAHVVADRRRVRVRLLSGDTYEAVVTAVDPVADIATLRIQTKEPL
PTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAA
IDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSSSGISGSQRR
YIGVMMLTLSPSILAELQLREPSFPDVQHGVLIHKVILGSPAHRAGLRPGDVILAIGEQM
VQNAEDVYEAVRTQSQLAVQIRRGRETLTLYVTPEVTE

>Macaca mulatta_HTRA2(ENSMMUP_2846)
MAAPRAGRGAGWSLRAWRALGGIRWGRRPRLTPDLRALLTSGTSDPRARVTYGTPSLWAR
LCVGVPEPRACLTSGTPGPRAQLTAVTPDTRTREASENSGTRSRAWLAVALGAGGAVLLL
LWGGGRGPPAVLAAVPGPPPASPRSQYNFIADVVEKTAPAVVYIEILDRHPFLGREVPIS
NGSGFVVAADGLIVTNAHVVADRRRVRVRLLSGDTYEAVVTAVDPVADIATLRIQTKEPL
PTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAA
IDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSSSGISGSQRR
YIGVMMLTLSPSILAELQLREPSFPDVQHGVLIHKVILGSPAHRAGLRPGDVILAIGGQM
VQNAEDVYEAVRTQSQLAVQIRRGRETLTLYVTPEVTE

>Mus musculus_HTRA2(ENSMUSP_87073)
MAALKAGRGANWSLRAWRALGGIFWRKPPLLAPDLRALLTSGTPDSQIWMTYGTPSLPAQ
VPEGFLASRADLTSRTPDLWARLNVGTSGSSDQEARRSPGSRRREWLAVAVGAGGAVVLL
LWGWGRGLSTVLAAVPAPPPTSPRSQYNFIADVVEKTAPAVVYIEILDRHPFSGREVPIS
NGSGFVVASDGLIVTNAHVVADRRRVRVRLPSGDTYEAMVTAVDPVADIATLRIQTKEPL
PTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQNNVEYIQTDAA
IDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSWFGTSGSQRR
YIGVMMLTLTPSILIELQLREPSFPDVQHGVLIHKVILGSPAHRAGLRPGDVILAIGEKL
AQNAEDVYEAVRTQSQLAVRIRRGSETLTLYVTPEVTE

>Rattus norvegicus_HTRA2(ENSRNOP_30076)
MAALKAGRGANWSLRAWRALGGIFWRKGPLLAPDLRALLTSGTPDPQARMTYGTPSLPAR
VPLGVLASRANLTSGTPDLWVRLTVGTPGSSDQEDCGSPGSRRREWLAVALGAGGAVLLL
LWGWGRGPSTVLAAVPAPPPTSPRSQYNFIADVVEKTAPAVVYIEILDRHPFSGREVPIS
NGSGFIVASDGLIVTNAHVVADRRRVRVRLPSGDTYEAMVTAVDPVADIATLRIQTKEPL
PTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAA
IDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSWFGISGSQRR
YIGVMMLTLTPSILAELQLREPSFPDVQHGVLIHKVILGSPAHRAGLRPADVILAIGEKM
IQNAEDVYEAVRTQSQLAVRIRRGPETLTLYVTPEVTE

>Oryctolagus cuniculus_HTRA2(ENSOCUP_13232)
MAALRAGRGAGWSLWGLRALGGIRWGKGPLLTSDLRALLTSGTPDLRARMTYGTPSLRAR
LAVGVPEPRAFLTSGSPDPRPRLTAGAPDSRPREASGTPGTRPRVWLAVALGAGGAVLLL
LWGGGRGPPAVLASVPAPPPTSPRSQYNFIADVVEKTAPAVVYIEILDRHPFSGREVPIS
NGSGFVVAADGLIVTNAHVVADRRRVRVRLPSGDTYEAMVTAVDPVADIATLRIQTKEPL
PTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAA
IDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSWFGISGSQRR
YIGVMMLTLTPSILAELQLREPSFPDVQHGVLIHKVILGSPAHRAGLRPGDVILAIGEQL
VQNAEDVYEAVRTQSQLAVRIRRGSETLTLYVTPEVTE

>Canis familiaris_HTRA2(ENSCAFP_12325)
MAALRAGRGAAWNLRGWRALGGVHSGKGPLLTPDLRALLTSGIPDPRARVTYGTPSLRAR
WSVGVPEPRTCLTSRTSDSRAWLAVGTPDPRTQEGSGTPGTRPRIWLAVALGAGGAVLLL
LWGGGRGPPAVLASVLGSPPSSPRSQYNFIADVVEKTAPAVVYIEILGRHPFSGREVPIS
NGSGFVVAADGLIVTNAHVVADRRRVRVRLLSGDTYEAVVTAVDPVADIATLRIQTKEPL
PTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAA
IDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSWFGISGSQRR
YIGVMMLTLTPSILAELQLREPSFPDVQHGVLIHKVILDSPAHRAGLRPGDVILAIGEQL
VQNAEDIYEAVRTQSQLAVRIRRGPETLTLYVTPEVTE

>Felis catus_HTRA2(ENSFCAP_6637)
MAALRAGRGAGWNLWGWRALGGVPWGKGPLLTPDLRALLTSGTPDPRARVTYGTPSLWAR
LSGGVPEPRTCLTSGTSDSRARLTAGSPDLKTREVSETPGTRPRIWLAVALGAGGAVLLL
LWGGGRGPPAVLASVLGSPPTSPRSQYNFIADVVEKTAPAVVYIEILGRHPFSGREVPIS
NGSGFVVAADGLIVTNAHVVADRRRVRVRLLSGDTYEAMVTAVDPVADIATLRIQTKEPL
PTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAA
IDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSWFGISGSQRR
YIGVMMLTLTPSILAELQLREPSFPDVQHGVLIHKVILDSPAHRAGLRPGDVILAIGEQL
VQNAEDIYEAVRTQSQLAVRIRRGPETLTLYVTPEVTE

>Bos taurus_HTRA2(ENSBTAP_26804)
MAALRAGRGAGWSLRGWRALWGGRWGKGPLLTPDLRALLTSGTPDPRTRVTYGTPSFRAR
LSVGVPEPRTCLRSRTSDLRARLIAGTPDPRTPEDSGTPGTRLRVWLAVALGAGGAVLLL
FWGGGRGPPAVLASVLGSPPTSPRSQYNFIADVVEKTAPAVVYIEILGRHPFSGREVPIS
NGSGFVVAADGLIVTNAHVVADRRRVRVRLPSGDTYEAVVTAVDPVADIATLRIQTKEPL
PTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPAKDLGLPQTNVEYIQTDAA
IDFGNSGGPLVNLDGEVIGVNTMKVTSGISFAIPSDRLREFLHRGEKKNSWFGISGSQRR
YIGVMMLTLTPSILAELQLREPSFPDVQHGVLIHKVILDSPAHRAGLRPGDVILAIGEQL
VQNAEDIYEAVRTQSQLAVRIRRGQETLTLYVTPEVTE

>Equus caballus_HTRA2(ENSECAP_520)
MAALRAGQGAGWSLRGWRALGGVRWGKGPLLTPDLRALLTSGTSDPRARVTHGTPSLQAR
LSGGVPEQRTCLTSGTSDSRAQLTGGNPDPRTREDSGTPGTRPRVWLAVALGAGGAVLLL
LWGGGRGPPAVLASVLGSPPTSPRSQYNFIADVVEKTAPAVVYIEILGRHPFSGREVPIS
NGSGFVVAADGLIVTNAHVVADRRRVRVRLPSGDTYEAVVTAVDPVADIATLRIQTKEPL
PTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAA
IDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSSLGISGSQRR
YIGVMMLTLTPSILAELQLREPSFPDVQHGVLIHKVILDSPAHRAGLRPGDVILAIGEQL
VQNAEDIYEAVRTQSQLAVRIRRGPETLTLYVTPEVTE

>Anolis carolinensis_HTRA2(ENSACAP_8508)
SPPPPRWRWAAMGACGAGAGLLLLLFFPRKPAEARPPVPSPPPSPRSTYNFIADVVERTA
PALVYIEILGRHPFSGREVPISNGSGFVVSSDGLIVTNAHVVANRRRVRVRLASGELYDA
TVRLVDQVADIATLKISPKKPLPTLRLGRSSEVRQGEFVVAMGSPFALQNTITSGIVSSA
QRGGRELGLSSSDIEYIQTDAAIDFGNSGGPLVNLDGEVIGVNTMKVTPGISFAIPSDRL
RAFLEKEEKSKDSWFGGKKEGKRRYIGVMMLTLTSSILSELKMRDPSFPDISYGVLIHKV
IIGSPAHQAGLKAGDVVVEINGRASRRAEDVYEAVRTQDHLTLLVHRGYEALLLTITPEV
TE

>Danio rerio_HTRA2a(ENSDARP_92827)
MATSHVNRCLLRTITRCHRDSSRQLNLTTVRALGHFSNFSSGKEEHVETVDPPRGSGGGS
GTSRLAVALGLGLGGAAAVFSLRGEDNKDALQRTVAVKNLLIDSILPTVQCASPFKPDSP
RYKYNFIADVVEKSTPAVVYIEIVGRHPFSGREVPISNGSGFIVSSDGLIVTNAHVVANK
RGVRVKLTNGETYNATVQDVDQAADIATIKINVKNPLPTLRLGKSSDVRQGEFVVAMGSP
FSLKNTITSGIVSSAQRGSKELGLSNSNMDYIQTDATIDFGNSGGPLINLDGEVIGINTM
KVTAGISFAIPSDRVRLFLDRSADKQNSWFGESGWKRRYIGVMMLTLTPRHPFSGREVPI
SNGSGFIISSDGLIVTNGHVVANKCGVRVKLTNDETYNATVQDVDQAADIASIKINVKNP
LPTLRLGKSSDVRQGEFVVAMGSPFSLKNTITSGIVSSAQRGSKELGLSNSNMDYIQTDA
TIDFGNSGGPLINLDGEVIGINTMKVTAGISFAIPLFLDRSADKQKSWFGESESKRRYIG
VMMLTLTPSIIKELRMRDPSFPDVSHGVLIHRVIVGSPANRAGMKPGDVIIEINGVKVNT
SEEIYNAVRTSESLNVVVRRGADLLMLHMTPESTE

>Danio rerio_HTRA2(ENSDARP_101935)
LFRHPFSGREVPISNGSGFIISSDGLIVTNAHAVANKRGVRVKLTNGETYNATVQDVDQA
ADIATIKINVKNPLPTLRLGKSSDVRQGEFVVAMGSPFSLKNTITSGIVSSAQRGSKELG
LSNSNMDYIQTDATIDFGNSGGPLIHLDGEVISINTMKVTAGISFAIPSDRVRLFLDRSA
DKQNSWFGESGSKRRYIGVMMLTLTPSIIDELRMRDPSFPDVSHGVLIHRVIVGSPANRA
GMKPGDVIIEINGVKVNTSEEIYNAVRTSESLNVVVRRGADLLMLHMTPESTER

>Takifugu rubripes_HTRA2a(ENSTRUP_31408)
PDSPRYKYNFIADVVEKSTPAVVYIEILGRHPFSGREVTVSNGSGFLISTDGLIVTNAHV
VANKRGVRVKLNNGEMYNATVQDVDQVADIATIKISVKNPLPTLPLGCSAQVRQGEFVVA
MGSPFALRNTITSGIVSSAQRGSKELGLSNTNMDYIQTDAAIDFGNSGGPLINLDGEVIG
INTMKVTAGISFAIPSDRLRLFLDRAEQKKSSWFRDSDTRRRYIGVMMLTLTPSIIAELK
LRDPSFPEVTHGVLIHRVIMGSPANRAGMIPGDIVVEINGAKANTSEEVYEAVRSSDHIS
MLVQRGGELLQLRVTPEYTE

>Takifugu rubripes_HTRA2b(ENSTRUP_18942)
MRLWVVLCATVLLAAEARIVKRLAIGCPDKCDKSQCAPVPADCLAGDVLDRCDCCPVCGA
GDGEQCGGTDDRECAEGLECLVTDGVEVSATVRRRGTAGMCVCTSSQPVCGSDGVSYRNI
CELKRVSNMAVKMQRPPVIFIQRGACGEGQQNPDSLRYKYNFIADVVEKIGPAVVHIELY
RKMMFTKRELAVASGSGFVVSEDGLIVTNAHVVANKHRVKVELKSGATFDAKVRDIDEKA
DIALIKIDAPTKLPVLLLGRSADLRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGL
RNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDKIRQFLAESHD
RQSESNGRFQHFHPFPSSGQTTTQKKFIGIRMLSITPTLAKELKEKQPDFPDVTSGVYVI
EVISRTPAARAGLQDKDVIISINGEQISSSSDVSEIIKTGSVLRTVVRRGNEDVILTIIP
EEMEP

>Gasterosteusaculeatus_HTRA2(ENSGACP_11279)
PDSPRFKYNFIADVVEKSTPAVVYIEIVGRHPFSGREVPVSNGSGFIISSDGLIVTNAHV
VANKKGVRVKLTNGETYNATVKDVDPVADIATIKISAKSPLPTLALGRSSDVRQGEFVVA
MGSPFSLRNTITSGIVSSVQRGSKELGLSNSNMDYIQTDAAIDFGNSGGPLINLDGEVIG
INTMKVTPGISFAIPSDRLTLFLDQAAKKKNSRSGESATKRRYIGVMMLTLTPSIISELK
LRDRSFPDVAYGILIHRVILGSPADRAGMLPGDVVVEINGVKVNTSEEIYQAVRSGDKIT
TVVQRGHQLLRLQITPESTEP

>Oryzias latipes_HTRA2(ENSORLP_19645)
MAVSAAVRKCFVSALVTQARCQRLNALPKNTFSRASSAVTCGHGEPTGRKSLYDRAEAEG
DSGQSGGSVLWTSLGLGLCGAAFLDSQKDKGVRGDSKSRRFLELLLPSAHCASPFKPDSP
RFKYNFIADVVEKSTPAVVYIEILGRHPFSGREVPVSNGSGFIISSDGLIVTNAHVVANK
RGVRVKLTNGDMYHASVQDVDPVADIATIKITTKDVQNPLPIETGQSSDIRQGEFVVAMG
SPFALRNTITSGIVSSAQRDSKELGLSNPNMEYIQTDATIDFGNSGGPLINLDGEVIGIN
TMKVTAGISFAIPSDRLKIFLDQAAKKTKSSVGESRTKARYIGVMMLTLTPSIITELQLR
DPMFPNVTHGILIHRVIIGSPASRAGMLAGDIVVEINGVKVNTSEEIYKAVRSSDRITML
VQRGKELLRLQVTPEFIDP

>Homo sapiens_HTRA3(ENSP_303766)
MQARALLLAALAALALAREPPAAPCPARCDVSRCPSPRCPGGYVPDLCNCCLVCAASEGE
PCGGPLDSPCGESLECVRGLCRCRWSHAVCGTDGHTYANVCALQAASRRALQLSGTPVRQ
LQKGACPLGLHQLSSPRYKFNFIADVVEKIAPAVVHIELFLRHPLFGRNVPLSSGSGFIM
SEAGLIITNAHVVSSNSAAPGRQQLKVQLQNGDSYEATIKDIDKKSDIATIKIHPKKKLP
VLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQREGRELGLRDSDMDYIQTDAII
NYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDRITRFLTEFQDKQIKDWKKRFIGIR
MRTITPSLVDELKASNPDFPEVSSGIYVQEVAPNSPSQRGGIQDGDIIVKVNGRPLVDSS
ELQEAVLTESPLLLEVRRGNDDLLFSIAPEVVM

>Pan troglodytes_HTRA3(ENSPTRP_27395)
MQARALLLAALAALALAREPPAAPCPARCDVSRCPSPRCPGGYVPDLCNCCLVCAASEGE
PCGGPLDSPCGESLECVRGLCRCRGSHAVCGTDGHTYANVCALQAASRRALQLSGTPVRQ
LQKGACPLGLHQLSSPRYKFNFIADVVEKIAPAVVHIELFLRHPLFGRNVPLSSGSGFIM
SEAGLIITNAHVVSSNSAAPGRQQLKVQLQNGDSYEATIKDIDKKSDIATIKIHPKYGNS
GGPLVNLDGEVIGINTLKVTAGISFAIPSDRITRFLTEFQDKQIKDWKKRFIGIRMRTIT
PSLVDELKASNPDFPEVSSGIYVQEVAPNSPSQ

>Gorilla gorilla_HTRA3(ENSGGOP_5241)
MPARALLLAALAALALAREPPAAPCPARCDVSRCPSPRCPGGYVPDLCNCCLVCAASEGE
PCGGPLDSPCGESLECVRGLCRCRWSHAVCGTDGHTYANVCALQAASRRALQLSGTPVRQ
LQKGACPLGLHQLSSPRYKFNFIADVVEKIAPAVVHIELFLRHPLFGRNVPLSSGSGFIM
SEAGLIITNAHVVSSNSAAPGRQQLKVQLQNGDSYEATIKDIDKKSDIATIKIHPKKKLP
VLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQREGRELGLQDSDMDYIQTDAII
NYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDRITRFLTEFQDKQIKDLANWKKRFI
GIRMRTITPSLVDELKASNPDFPEVSSGIYVQEVAPNSPSQRGGIQDGDIIVKVNGRPLV
DSSELQEAVLTESPLLLEVRRGNDDLLFSIAPEVVMDP

>Pongoabelii_HTRA3(ENSPPYP_16273)
LAQPLPARVTEEPPAAPASLAWSVSRCPSPRCPGGYVPDLCNCCLVCAASEGEPCGGPLD
SPCGESLECVRGLCRCRWSHAVCGTDGHTYANVCALQAASRRALQLSGTPVRQLQKGACP
LGLHQLSSPRYKFNFIADVVEKIAPAVVHIELFLRHPLFGRNVPLSSGSGFIMSEAGLII
TNAHVVSSNSAAPGRQQLKVQLQNGDSYEATIKDIDKKSDIATIKIHPKKKPTLCCCVGH
SADLRPGEFWWAIGSPFALQNTVTTGIVSTAQRGGQGAGPPGTPTWDYIHCFLPLQYGNS
GGPLVNLDGEVIGINTLKVTAGISFAIPSDRITRFLTEFQDKQTKDWKKRFIGIRMRTIT
PSLVDELKASNPDFPEVSSGIYVQEVAPNSPSQRGGIQDGDIIVKVNGRPLVDSSELQEA
VLTESPLLLEVRRGNDDLLFSIAPEVVM

>Macaca mulatta_HTRA3(ENSMMUP_29846)
XCGSPLDSPCGESLECVRGLCRCRWTHAVCGTDGHTYANVCALQAASRRALQLSGTPVRQ
LQKGACPLGLRQLSSPRYKFNFIADVVEKIAPAVVHIELFLRHPLFGRNVPLSSGSGFIM
SEAGLIITNAHVVSSNNAASGRQQLKVQLQNGDSYEATIKDIDKKSDIATIKIHPKKKLP
VLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQREGRELGLRDSDMDYIQTDAII
NYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDRITRFLTEFQDKQIKDWKKRFIGIR
MRTITPSLVDELKASNPDFPEVSSGIYVQEVTPNSPSQRGGIQDGDIIVKVNGRPLVDSS
ELQEAVLTESPLLLEVRRGNDDLLFSIAPEVVM

>Callithrix jacchus_HTRA3(ENSCJAP_25615)
SPTPPPAAGPAAMQARALFLAALVALALAREPPAAPCPARCDVSRCPSPRCPGGYVPDLC
NCCLVCAASEGEPCGGPLDSPCGESLECVRGLCRCRWTHAVCGTDGHTYANVCALQAASR
RALQLSGTPVRQLQKGACPLGLHQLSSPRYKFNFIADVVEKIAPAVVHIELFLRHPLFGR
NVPLSSGSGFIMSEAGLIVTNAHVVTSRNTASGRQQLKVQLQNGDSYEATIKDIDKKSDI
ATIKIHPKKKLPVLLLGQSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQREGRELGLRD
SDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDRITRFLTEFQDKH
IKGKELTYWKKRFIGIRMRTITPSLVDELKASNPDFPGVSRGIYVQEVAPNSPSQRGGIQ
DGDIIVKVNGRPLVDSSELQEAILNESPLLLEVRRGNDDLLFSIAPEVVIGP

>Mus musculus_HTRA3(ENSMUSP_84910)
MQARALLPATLAILATLAVLALAREPPAAPCPARCDVSRCPSPRCPGGYVPDLCNCCLVC
AASEGEPCGRPLDSPCGDSLECVRGVCRCRWTHTVCGTDGHTYADVCALQAASRRALQVS
GTPVRQLQKGACPSGLHQLTSPRYKFNFIADVVEKIAPAVVHIELFLRHPLFGRNVPLSS
GSGFIMSEAGLIVTNAHVVSSSSTASGRQQLKVQLQNGDAYEATIQDIDKKSDIATIVIH
PKKKLPVLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQRDGKELGLRDSDMDYI
QTDAIINYGNSGGPLVNLDGEVIGINTLKVAAGISFAIPSDRITRFLSEFQNKHVKDWKK
RFIGIRMRTITPSLVEELKAANPDFPAVSSGIYVQEVVPNSPSQRGGIQDGDIIVKVNGR
PLADSSELQEAVLNESSLLLEVRRGNDDLLFSIIPEVVM

>Rattus norvegicus_HTRA3(ENSRNOP_10852)
MQARALLPATLATLATLAVSVLAREPPAAPCPARCDVSRCPSPRCPGGYVPDLCNCCLVC
AASEGEPCGRPLDSPCGDSLECVRGVCRCRWTHTVCGTDGHTYADVCALQAASRRALQIS
GTPVRQLQKGACPSGLHQLTSPRYKFNFIADVVEKIAPAVVHIELFLRHPLFGRNVPLSS
GSGFIMSEAGLIVTNAHVVSSSNTASGRQQLKVQLQNGDAYEATIQDIDKKSDIATILIH
PNKKLPVLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQRDGKELGLRDSDMDYI
QTDAIINYGNSGGPLVNLDGEVIGINTLKVAAGISFAIPSDRITRFLSEFQDKHVKDWKK
RFIGIRMRTITPSLVEELKTANPDFPAVSSGIYVQEVVPNSPSQRGGIQDGDIIVKVNGR
PLVDSSELQEAVLNESSLLLEVRRGNDDLLFSIMPEVVM

>Canis familiaris_HTRA3(ENSCAFP_21445)
RLLVSPCEKSVECARGVFRCGWAHPVCGTDGHTYANVCALQAASRRALELSGTPVRQLQK
GACPSGLHQLTSPRYKFNFIADVVEKIAPAVVHIELFLRHPLFGRNVPLSSGSGFIMSEA
GLIVTNAHVVSSTNAVSGRQQLKVQLQNGDTYEATIKDIDKKSDIATIKIHPKKKLPALL
LGRSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQRDGKELGLRDSDMDYIQTDAIINYG
NSGGPLVNLDGEVIGINTLKVAAGISFAIPSDRITRFLTEFQDKHVKDWKKRFIGIRMRT
ITPSLVEELKASNPDFPSVSSGIYVQEVVPNSPSQRGGIQDGDIIVKVNGRPLADSSELQ
EAVLTESPLLLEVRRGNDDILFSISPEVVL

>Felis catus_HTRA3(ENSFCAP_14182)
QAASRRALQLSGTPVRQLQKGACPSGLHQLTSPRYKFNFIADVVEKIAPAVVHIELFLRH
PLFGRNVPLSSGSGFIMSEAGLIVTNAHVVSTSNAVSGRQQLKVQLQNGDTYEATIKDID
KKSDIATIQIHPKKKLPALLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQRDGKE
LGLRDSDMDYVQTDAIINYGNSGGPLVNLDGEVIGINTLKVAAGISFAIPSDRITRFLTE
FQDRHAKDWKKRFIGIRMRTITPSLLEELKASDPDFPSVSSGIYVQEVVPNSPSQSRGGI
QDGDIIVKVNGRPLADSSELQEAVLTESPLLLEVRRGNDDLLFSIAPEVVL

>Equus caballus_HTRA3(ENSECAP_1077)
LAGLAALALATELPAAPCPASCDVSRCPSSRCPGGYVPDLCNCCLVCAAGEGEPCGRPLD
SPCGESLECARGVCRCRWAHAVCGTDGHTYANVCALQAASRRALQLSGTPVRQLQKGACP
SGLHHLTSPRYKFNFIADVVEKIAPAVVHIELFLRHPLFGRNVPLSSGSGFIMSEAGLIV
TNAHVVSSTNSVSGRQQLKVQLQNGDTYEATIQDIDKKSDIATIKIHPKKKLPALLLGHS
GDLRPGEFVVAIGSPFALQNTVTTGIVSTAQRDGKELGLRDSDMDYIQTDAIINYGNSGG
PLVNLDGEVIGINTLKVAAGISFAIPSDRITRFLTEFQDKHIKDWKKRFIGIRMRTITPS
LLEELKASNPDLPTVSSGIYVQEVVPNSPSQRGGIQDGDIIVKVNGRPLADSSELQEAVL
NESPLLLEVRRGNDDLLFSIAPEVVV

>Gallus gallus_HTRA3(ENSGALP_25068)
MRLSLLSPLLLLCLSRSRGSAELPAARAKCPTRCDVSKCPSPSCPSGYVPDRCNCCLICA
AGEGDSCGRKEDPPCGDSLDCRYPMGKRFAKGVCQCKLSVQVCGSDGRTYDNICQLKAVS
RKALQHGLPAVAQVQKGACESGHLQSSSPRYKFNFIADVVEKIAPAVVHIELFLRHPLFG
RNVPLSSGSGFIMSDSGLIVTNAHVVSSTNAISGRQQLKVQLQNGDTYEATIRDIDKKSD
IATIKIHPKKKLPVLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQRDGKELGLR
DSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDRITQFLTESLDK
QNKDSKKRFIGIRMLTITPALVEELKHNNADFPDVRSGIYVHEVVPNSPSHRGGIQDGDI
IVKVNGRPLMTSSDLQEAVMNESPLLLEVRRGNDDLLFNIEPEIVM

>Taeniopygia guttata_HTRA3(ENSTGUP_10582)
AKCPARCDVSTCPSPSCPSGYVPDRCGCCLICAAGEGDSCGRKEDPPCGDSLDCRYPMGK
RFAKGVCQCKLSAQVCGSDGRTYDNICQLKAVSRKALQHGLPAVAQVQKGACESGRSMSS
SPRYKFNFIADVVEKIAPAVVHIELFLRHPLFGRNVPLSSGSGFIMSDSGLIVTNAHVVS
STNAISGRQQLKVQLQNGDTYEATIKDIDKKSDIATIKIHPKKKLPVLLLGHSADLRPGE
FVVAIGSPFALQNTVTTGIVSTAQRDGKELGLRDSDMDYIQTDAIINYGNSGGPLVNLDG
EVIGINTLKVTAGISFAIPSDRITQFLTESHDKQSKGKTDGKKRFIGIRMLTITPALVEE
LKHSNADFPDVRSGIYVHEVVPNSPSHRGGIQDGDIIVKVNGRPLLTSSDLQEAVMNESP
LLLEVRRGNDDLLFNIEPE

>Anolis carolinensis_HTRA3(ENSACAP_11769)
PAGDRCPARCDVSRCPSSICPSGYVPDGCNCCLVCAAGEGEACGRAEDPPCGEGLQCRSF
NAEPERRGVCQCKLGAAVCGSDGRSYANACRLQTAARQALQQGRPPVRQVQKGACRAAST
GHQQLNSPRFKFNFIADVVEKIAPAVVHIELFLRHPLFGHNVPLSSGSGFIMSDTGLIVT
NAHVVSSSSTVTGRQQLKVQLQDGDTYEAKIKDIDKKSDIATIKINPRKKLPALSIGQSG
DLRPGEFVVAMGSPFALQNTVTTGIVSTAQRDGKELGLKDSDMDYIQTDAIINYGNSGGP
LVNLDGEVIGINTLKVTAGISFAIPSDRIAQFLSENYDKKGNSKIDGKKRFIGIRMLTIT
PVLMEELKVNNPDFPDVISGIYVHEVVPNSPSQRGGIEDGDIIVKVNGRPLKTSADLQDA
VMNESPLLLEVRRGNDDLLFNIEPEVVIP

>Xenopus tropicalis_HTRA3(ENSXETP_62635)
ETPQLSELPISLLLRMKLCAWLPLCALLTLLSGATRTGACPARCDVSRCPSPICPSGYVP
DRCNCCLICAAGEGEPCGREGDPPCGDSLQCKPPPGMRGLKGSCQCKHTNPVCANDGQTY
DNLCQLKAASRRALQKGHSPVVLVQKGACQSASIGHQHPNSPRYKFNFIADVVEKIAPAV
VHIELFLRHPLFGRNVPLSSGSGFIISDLGLIVTNAHVVSSSNTVSGRQYLKVQLHNGDS
YEATIKDIDKKSDIATIKIYPRKKLPVLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIV
STAQRDGKELGLRDSDMDYVQTDAIINYGNSGGPLVNLDGEVIGINTLKVAAGISFAIPS
DRITKFMTESQDKKYKANNDGKKRFIGIKMLTITPSFAEEKKLHNPDFPDVTSGIYVHEV
VPNSPAQRGGIQDGDIIVKVNGRPLVTSGDLHEAVMNESPLLLEVRRGNDDMLFNLEPEV
SM

>Danio rerio_HTRA3(ENSDARP_16871)
EMQVILCVSVVFLYYKAAVADKLKCPERCDVSKCPSPSCPSGYVPDRCDCCLVCAQGEGE
PCGRKDDLPCGDGLECKHPSGKRLSKGVCQCRYSSKVCGSDGNTYGNICQLKAVSRKALQ
QGLPAVTNVHKGPCENNQEEKNQSSSSRWKFINDFVKKCSKVEIISHIFNHPLFGRTVPL
SSGSGFVMSETGLIVTNAHVVSSTTSVSGHQRLKVQMRDGDVYEATIQDIDKKSDIATIK
INPQKKLPVLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQRDGKELGLQDSDMD
YIQTDAIINYGNSGGPLVNLDGEVIGINTLKVAAGISFAIPSDRITRFLNDSLGKQNKET
RSVKKRFIGIRMLTITDALVEELKQQNPDFPDVSSGIFVHEVVPHSPAQKGGIRDGDIIV
KLNGEPLLSTSDLKEALNQDMTLLLEVRRGNDDLLFNIEPDIIMQ

>Takifugu rubripes_HTRA3(ENSTRUP_4632)
TVLRQMRTAGVNLLLCAPLFLYLADVLAAQSELKCPTRCDVSTCPSPSCPSGYVPDRCNC
CLVCAQGEGEACGRKDDLPCGDGLECKHPAGKRLAKGVCRCKFSSEVCGSDGKTYGNVCQ
LKASSRKALLQGQPGVSQVQRGPCESSSGSSHATSPRFKFNFIADVVEKIAPAVVHIELF
LRHPLFGRTIPLSSGSGFVMSENGLIVTNAHVVSSTSAATGQQHLKVQMHNGDIYEASIK
DIDKKSDIATIKINPQAKLPLLFLGQSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQRD
GKELGLRDSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVAAGISFAIPSDRITRF
LSDSFQRHRDVKSVTKRFIGIRMLTVTPALIEELKQQNPDFPDISSGIYVHGVVPLSPAD
KGGIKDGDVIVKLNGKPLKSTADLQGALQEETALLLEVRRDNDDLLFNIEPDVIM

>Tetraodon nigroviridis_HTRA3(ENSTNIP_6685)
KERLRVTERSSMNLLLRAPLLLYLLDVLGAQPEAKCPTRCDVSACPSPGCPGGYVPDRCN
CCLVCAHGEGEACGRKDDLPCGDGLECQHPAGRRLAPGVCRCKLSSEVCGSDGKTYGNAC
QLQASSRKALQQGQPGLRQVRRGPCESGSGSSRASSPRYKFNFIADVVEKIAPAVVHIEL
FLRHPLFGRTVPLSSGSGFLVSENGLIVTNAHVVSSTSPGTAQQHLKVQMQNGDTYEASI
KDIDKKSDIATIKVEPQVKLPVLFLGQSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQR
DGRELGLRDSDMDYVQTDAIINYGNSGGPLVNLDGEVIGINTLKVAAGISFAIPSDRITQ
FLSHALQRHGKDAKSAKKRFIGIRMLTVTPGLMEELKQQNPDFPDIGGGIYVHGVVPLSP
ADKGGIKEGDVLVKLNGRPLASTADLQGALQEEAALLLEVRRGNDDLLFNIQPDLILQ

>Gasterosteusaculeatus_HTRA3(ENSGACP_991)
KMHILLYAAVFLYLKESAFAKPKDKCPTRCDVSTCPSPGCPSGYVPDRCNCCLVCAQAEG
EPCGRKDDLPCGDALECKHPAGKRLSKGFCRCRFRQDVCGSNGKTYGNVCQLKATSRKAL
QQGLPAFNLAHKGPCDNSTASIGPSHADSPRYKFNFIADVVEKIAPAVVHIELFLRHPLF
GRNIPLSSGSGFLLSDNGLIVTNAHVVSSTTPVSGQQHLKVQMHDGHVYEANIKDIDKKS
DIATIKINSQMKLPVLFLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQRDGKELGL
KDSDMDYQTDAIINYGNSGGPLVNLDGEVIGINTLKVAAGISFAIPADRITLFLNDSLDK
HNKGVSDSDVIGPGLNIFKLESLSDVRSIKKRFIGISMLTITPALIEKLKQQNLDFPDVT
SGIYVHGVIPHSPAQKGGIKEGDIIVKLNGKSLMATADLQEALQEETALLLEVRRDNDDL
LFNIEPDVIMQ

>Oryzias latipes_HTRA3(ENSORLP_25520)
PTFASRTIIMRVVLWFSSVLLYLGGFANAEPKAKCPTRCDVSSCPSPSCPSGYVPDRCNC
CLVCAGAEGEPCGRKDDLPCGDGLECKHPAGKRLSKGFCQCKLGHRVCGSDGKTYRNVCQ
LKATSRAALQQGQPGVSQTHKGPCESSAGPSRTSSPRYKFNFIADVVEKIAPAVVHIELF
LRHPLLGRNIALSSGSGFVMTENGLIVTNAHVVSSSSPVKVQMHNGDVYEATIKDIDKKS
DIATIKINPQIKLPVLFLGQSADLRPGEFVVAIGSPFALQNTVTTGIVSSAQRDGKELGL
RDSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVAAGISFAIPSDRITRFLNDSLN
KHSKELRPIKKRFIGIRMLTITPALIEELKQQNSDFPNVTSGIYVHEVVPHSPAQKGGIK
DGDIIVKLNGKPLTSTSDLQAALQEETALLLEIRRDNDDLLFNIEPDVIMQ

>Homo sapiens_HTRA4(ENSP_305919)
MIRPQLRTAGLGRCLLPGLLLLLVPVLWAGAEKLHTQPSCPAVCQPTRCPALPTCALGTT
PVFDLCRCCRVCPAAEREVCGGAQGQPCAPGLQCLQPLRPGFPSTCGCPTLGGAVCGSDR
RTYPSMCALRAENRAARRLGKVPAVPVQWGNCGDTGTRSAGPLRRNYNFIAAVVEKVAPS
VVHVQLWGRLLHGSRLVPVYSGSGFIVSEDGLIITNAHVVRNQQWIEVVLQNGARYEAVV
KDIDLKLDLAVIKIESNAELPVLMLGRSSDLRAGEFVVALGSPFSLQNTATAGIVSTKQR
GGKELGMKDSDMDYVQIDATINYGNSGGPLVNLDGDVIGVNSLRVTDGISFAIPSDRVRQ
FLAEYHEHQMKGKAFSNKKYLGLQMLSLTVPLSEELKMHYPDFPDVSSGVYVCKVVEGTA
AQSSGLRDHDVIVNINGKPITTTTDVVKALDSDSLSMAVLRGKDNLLLTVIPETIN

>Pan troglodytes_HTRA4(ENSPTRP_34549)
MIRPQLRPAGLGRCLLPGLLLLLVPVLWVGAEKLHTQPSCPAVCQPTRCPALPTCALGTT
PVFDLCRCCRVCPAAEREVCGGAQGQPCAPGLQCLQPLRPGFPSTCGCPTLGGAVCGSDR
RTYPSMCALRAENRAARRLGKVPAMPVQWGNCGDTGTRSAGPLRRNYNFIAAVVEKVAPS
VVHVQLWGRLLHGSRLVPVYSGSGFIVSEDGLIITNAHVVRNQQWIEVVLQNGARYEAVV
KDIDLKLDLAVIKIESNAELPVLMLGRSSDLRAGEFVVALGSPFSLQNTATAGIVSTKQR
GGKELGMKDSDMDYVQIDATINYGNSGGPLVNLDGDVIGVNSLRVTDGISFAIPSDRVRQ
FLAEYHEHQMKGKAFSNKKYLGLQMLSLTVPLSEELKMHYPDFPDVSSGVYVCKVVEGTA
AQSSGLRDHDVIVNINGKPITTTTDVVKALDSDSLSMAVLRGKDNLLLTVIPETIN
 
>Gorilla gorilla_HTRA4(ENSGGOP_5915)
MIRPQLRPAGLGRCLLPGLLLLLVSVLWAGAEKLHTQPSCPTVCQPTRCPALPTCALGTT
PVFDLCRCCRVCPAAEREVCGGAQGQPCAPGLQCLQPLRPGFPSTCSCPTLGGAVCGSDR
RTYPSMCALRAENRAARRLGKVPAVPVQWGNCGDTGTRSAGPLRRNYNFIAAVVEKVAPS
VVHVQLWGRLLHGSRLVPVYSGSGFIVSEDGLIITNAHVVRNQQWIEVALQNGARYEAVV
KDIDLKLDLAVIKIEPNAELPVLMLGRSSDLRAGEFVVALGSPFSLQNTATAGIVSTKQR
GGKELGMKDSDMDYIQIDATINNGNSGGPLVNLDGDVIGVNSLRVTDGISFAIPSDRVRQ
FLAEYHEHQMKGKAFSNKKYLGLQMLSLTVPLSEELKMHYPDFPNVSSGVYVCKVVEGTA
AQSSGLRDHDVIVNINGKPITTTTDVVKALDSDSLSMAVLRGKDNLLLTVIPETIN

>Macaca mulatta_HTRA4(ENSMMUP_7924)
MIRPQLRPAGLGRCLLPGLLLLLVPVLWAGAARLHTQLACPAVCQPTRCPALPTCSLGTT
PVLDLCRCCRVCPAAEGQVCGGTQGQPCAPGLQCLKPLRPGLPSTCGCPTKGVAVCGSDR
RTYPSLCALRTENRAARRLGNISAVPVQWGDCGDTGSRRAGTLRRNYNFIAAVVEKVAPS
VVHMQLWGRLLHGRMPVPVYSGSGFIVSEDGLIITNAHVVRNQQWIEVVLQNGARYEAVV
KDIDLKLDLAVIKIEPNADLPVLMLGRSSDLRAGEFVVALGSPVSLQNTATAGIVSTKQR
KGKELGMKDSDIDYVQIDAAINPGNSGGPLVNLDGDVVGVNSLRVTEGISFAIPSDRVRP
FLEEYHKRQLTGKARMVFSNKKYLGLQMLPLTMPLSKELKIHYPDFPDVSSGVYVCKVVE
GTAAQSSGLRDHDVIVKINGKPITTTTDVLEALDSDSLSMAVLRGKDNLLLTVIPEVIN

>Callithrix jacchus_HTRA4(ENSCJAP_4210)
MIRPQLRPAGLGPCLLPGLLLLLVPVPWAGAKRLHAQLACPAVCQPTRCPALPRCALGTA
PVLDLCRCCRVCPAAEGEVCGGARGRPCAPGLQCLQSLGPWLPSTCGCPTLGAAVCGSDR
RTYPSLCALRANNRAARRRGEVPAVPVQWGDCRDTGTRSAGPLRSNYNFIAPVVEKVAPS
VVHLQLWRRLLPGSKPVPVYSGSGFIVSEDGLIITNAHVVMNQQGIEVELQSGAHYEAII
KDIDLKLDLAVIKIESNADLPVLLLGRSSDLRAGEFVVALGSPFSLQKTATAGIVSTTHR
GSKELGIENSDVDYIQTDAIVNQGNSGGPLVNLDGDVIGVNTLRMADGISFAVPSDRVRE
FLAEYHEHQLKGKAFSQKKYLGLQMLPLTMPLIQEMKMRDPAFPNVSSGVYVCKVIEGTS
AESSGLRGHDVIVNINGKPVTTTTDVVEALDSDSLSMVVLRGRSNLFLTVTPEIIN

>Mus musculus_HTRA4(ENSMUSP_81044)
MSFQRLWAVRTQFLLLWLLLPAVPVPWAEARRSRVSLPCPDACDPTRCPTLPTCSAGLAP
VPDRCGCCRVCAAAEGQECGGARGRPCAPRLRCGAPFSRDPSGGAWLGTCGCAEGAEDAV
VCGSDGRTYPSLCALRKENRAARQRGALPAVPVQKGACEEAGTTRAGRLRRKYNFIAAVV
EKVAPSVVHLQLFRRSPLTNQEIPSSSGSGFIVSEDGLIVTNAHVLTNQQKIQVELQSGA
RYEATVKDIDHKLDLALIKIEPDTELPVLLLGRSSDLRAGEFVVALGSPFSLQNTVTAGI
VSTTQRGGRELGLKNSDIDYIQTDAIINHGNSGGPLVNLDGDVIGINTLKVTAGISFAIP
SDRIRQFLEDYHERQLKGKAPLQKKYLGLRMLPLTLNLLQEMKRQDPEFPDVSSGVFVYE
VIQGSAAASSGLRDHDVIVSINGQPVTTTTDVIEAVKDNDFLSIIVLRGSQTLFLTVTPE
IIN

>Rattus norvegicus_HTRA4(ENSRNOP_22166)
MSRSKMSSQRLWAVRAQFLLLWLLLWAAPVPWAEARRSRVSLPCPDACDPTRCPPLPSCS
AGSALVPDRCGCCQVCAAVEGQECGGARGRPCVPGLRCGAPFSREPSGRAWLGTCGCAEG
AEGAAVCGSDGRTYPSLCALRKENRAARQRGALPAVPVQKGACGDSGTTRAGRLRTKYNF
IAAVVEKVAPSVVHLQLFRRSPLTNQEIPSSSGSGFIVSEDGLIVTNAHVLTNQQKIQVE
LQNGAQYEATVKDIDHKLDLALIPVMSDXDLPVLLLGRSSDLRAGEFVVALGSPFSLQNT
VTAGIVSTTQRGGKELGLKDSDIDYIQTDAIINHGNSGGPLVNLDGDVIGINTLKVTAGI
SFAIPSDRIRQFLADYHERQLKGKAPLQKKYLGLRMLPLTLNLLQEMKRQDPDFPDVSSG
VFVYEVIQGSAAASSGLRDHDVIVSINGQPVTTTTDVIEAVKDNAFLSIIVLRGSQTLFL
TVTPEIIN

>Oryctolagus cuniculus_HTRA4(ENSOCUP_72)
MPRPQRLPAGLGPLLWLGLLLLGPGPVPSVEARRSRASMPCPATCEPTRCPPLPTCSAGI
TPVLDRCRCCRVCAAAEGEACGGLWGRPCALGLQCRAERVGGAWQGTCGCPAVGAAMCGS
DGRTYPSLCALRAENRAARLRGALPAVPVQKGSCGDPGTGSAGRLRSKYNFIAAVVEKVA
PAVVHLQLFRRSPLSSKDIPASSGSGFIVSEDGLIVTNAHVLTNQQRIQVELQSGVQYEA
TVKDIDHKLDLALIKIEPNTDLPVLLLGRSSDLRAGEFVVALGSPFSLQDTVTAGIVSTT
QRGGKELGLKDSDMDYIQTDAIINHGNSGGPLVNLDGDVIGINTLKVTAGISFAIPSDRI
RQFLADYHERQLKGKSLLQKKYLGLRMLPLTMNLLQEMKRQDPDFPDVSSGVLVYEVIQG
TAAESSGLRDHDVIVSINGQPVTTTTDVIEAVKDNDSLSVIVHRGRETLLLMVTPEIIKP

>Canis familiaris_HTRA4(ENSCAFP_8772)
PLRGARGGTCGCPAGAAVCGSDGRTYPSLCELRAQNRAARLRGALPAVPVLKGDCAGREA
WSVGRLRSQYNFLAAVVEKVAPSVVHLQLFRRSPLSSKDMPASSGSGFIVSEDGLIVTNA
HVITNQQRIQVELQSGVQYEATIKDIDHKLDLALIKIEPNGDLPVLLLGRSSDLQAGEFV
VALGSPFSLQNTVTAGIVSTTQRGGRELGLKDSDMDYIQTDAIINHGNSGGPLVNLDGDV
IGINTLKVTAGISFAIPSDRIRQFLAEFHERQLKGKALSQKKYLGLRMLPLTMNLLQEMK
RQDPDFPDVSSGVFVYEVIQGTAAESSGLRDHDVIVSINGQPVTTTTDVIEAVKDSDSLS
IMVLRGSQTLILTVTPEIIN

>Felis catus_HTRA4(ENSFCAP_2387)
PAVAATAPAACAQGRVLDRCRCCRVCAAAEGEACGGTLGRRCAPGLQCRAPLSAQRFRGA
WMGTCGCPAAGAAVCGSDGRTYPNLCALRAENRAARLRGALPAVPVLKGDCADQGTRSVG
RLRSKYNFIAAVVEKVAPSVVHLQLFRRDRSPLSSKDIPASSGSGFIVSEDGLIVTNAHV
LTNQQRIQVELQSGVQYEATVKDIDHKLDLALIKIEPNTDLPVLLLGRSSDLWAGEFVVA
LGSPFSLQNTVTAGIVSTTQRGGKELGLKDSNMDYIQTDAIINHGNSGGPLVNLDGDVIG
INTLKVTAGISFAIPSDRIRQFLAEFHERQLKGKALSQKKYLGLRMLPLTMNLLQEMKRQ
DPDFPDVSSGVFVYEVIQGTAAESSGLRDHDVIVSINGQPVTTTTDVTQAVKDSDSLSMM
VRRGSQTLILTVTPEIIN

>Bos taurus_HTRA4(ENSBTAP_4564)
MARPLQRPAGLGPFVLLWLLLPAPSGRGVQAGRAWPVPRCPAACEPTRCPPLPRCSVGTA
PVLDRCGCCRVCAAAEGEACGGPLGRPCAPGLQCLAPRAPRLLGGRPLGTCGCPAAGATV
CGSDGRTYRSLCALRAENRAARLRGALPAVPVQKGDCGDPGTGSAGWLRNKFNFIASVVE
KVAPSVVHLQLFRRDRSPLGSEDVPVSSASGFIVSEDGLIVTNAHVLTNQQRIQVELQSG
VQYEATVKDVDHKLDLALIKIEPNADLPVLLLGKSSDLRAGEFVVALGSPFSLQNTVTAG
IVSTTQRGGKELGLKDSDMDYIQTDAIINHGNSGGPLVNLDGDVIGINTLKVTAGISFAI
PSDRIRQFLAEFHERQLKGKALSQKKYLGLRMLPLTMNLLQEMKRQDPEFPDVASGVFVH
EVIQGTAAESSGLKDHDVIVSINGLPVTTTTDVIEAVKANDSLSLLVRRKSQTLILTVTP
EIIN

>Equus caballus_HTRA4(ENSECAP_10150)
LRSKYNFIAAVVEKVAPSVVHLQLFRRSPLSNKDIPASSGSGFIVSEDGLIVTNAHVLTN
QQRIQVELQSGVQYEATIKDIDHKLDLALIKIEPNTDLPVLLLGKSSDLRAGEFVVALGS
PFSLQNTVTAGIVSTTQRGGKELGLKDSDMDYIQTDAIINHGNSGGPLVNLDGDVIGINT
LKVTAGISFAIPSDRIRQFLAEFHERQLKGKALSQKKYLGLRMLPLTMNLLQELKRQDPD
FPDVSSGVFVYEVIQATAAESSGLRDHDVIVSINGQPVITTSDVIEAVKDHDSFSIMVRR
GSQTLILTVTPEVIN

>Danio rerio_HTRA4(ENSDARP_50541)
MMWKLLACVFMASTLHARVLRKRHSTCAHQCDLSRCSSSLEYCYFGVVMDSCGCCSVCAA
GEGDYCGEDRLGVCGAGMTCEERSAERSTCVCDSHEPVCGSDGRTYPSICRLKAENRRAK
TSGIPAVIFIQRGPCETGSRNPSSMRYKFNFIADVVDKIAPAVVHLELFSRLPFSNQDVP
VSSGSGFIVSEDGWIVTNAHVLSNKQRIKVELKNGMLYDATIKDVDQKLDIALIKIDSET
ALPVLLLGRSSDLRPGEFVVAVGSPFSLQNTVTTGIISTTHRGGHELGLQNSDMEYIQTD
AIINYGNSGGPLVNLDGDVIGINTLKVTPGISFAIPSDRIRQFLADSYERQRKGRTLTKK
KYMGVRMLQLSAALIRELREKESSFPDVSSGVYVYEVIPGTAAFSAGMLNQDVIISINGQ
PVYSTEDVSQAVQSNEILSLMVRRAQKEITLTVVPGEVD

>Ciona intestinalis_(ENSCINP_35284)
GAGNTGGNTRRGAFNFVADVVQVAGPAVVHIERLVNVPFTRRAVAVSNGSGFLVESNGLI
ITNAHVVGNQSALNVKLQDGREFEGQVIGIDEARDIAAVKINCTGLPKIPLGTTRDLRPG
EWVVAIGSPLALKNTVTAGIVSNMCRAGKELGLRDEEKRDMEYIQTDATINVGNSGGPLV
NLDGEVIGINSMMASAGIGFAIPIDYVRDFLQQLEHGQQTRVQHTRRWIGVSMLSLTPEI
SSHLRARNPDFPDVTTGVYVHKVTPDSPSDIAGVQNGDVIIKINGKQINGVSDVLETLKQ
NQVLNASICRRGRTIVVRIIAEEIVH

>Branchiostoma floridae_(XP_2603825)
MTRTGFYLRTCSTSVGNNTSKGYKYLRDSGIVVGCFAWGYVIGKFGVPYIWPSTDSADKEKSSIVKKVDA
AEPFYGGEGYGGIPRSKQFNFIADVVEIASPAVVYIEIQGKNPFTGGRAPTSNGSGFIVREDGLVVTNAH
VVANKRYVKVRLQDGRLLDGVVTLVDQAADIAAVKIINCNTPLKTVKLGNSSTLRPGEWVVAMGSPLSLS
NTITAGVISSVQRGSRELGLRHNDMDYIQTDAAINFGNSGGPLVNLDGEVIGVNTMKVTTGISFAIPIDK
VKEFLKNVEEKEKAQKGWFGRGQVAPPSPPKRRYLGVTMVTLTPNIIMELQERRTDFPDVRTGVLVHRII
VGSPAYSAGIRPGDVITSINGRQVTSARDIYDAVNSGQQLNITCHRGRTVHHLQVTPEEAD

>Drosophila melanogaster_(FBpp00303078)
MALRGSHRLEVIFKRCIASPVLHSHAANRRSSQLAIKEGDPNSNGNSGQYQQNGEQKEKG
WRRLVRFFVPFSLGAVVSAAIIQREDLTPTIAASKMTGRRRDFNFIADVVAGCADSVVYI
EIKDTRHFDYFSGQPITASNGSGFIIEQNGLILTNAHVVINKPHTMVQVRLSDGRTFPAT
IEDVDQTSDLATLRIQVNNLSVMRLGKSSTLRSGEWVVALGSPLALSNTVTAGVISSTQR
ASQELGLRNRDINYLQTDAAITFGNSGGPLVNLDGEAIGVNSMKVTAGISFAIPIDYVKV
FLERAAEKRKKGSAYKTGYPVKRYMGITMLTLTPDILFELKSRSQNMPSNLTHGVLVWKV
IVGSPAHSGGLQPGDIVTHINKKEIKNSSDVYDALADNSKTLDIVILRGVKQMHVTITPE
DP

>Apis mellifera_(XP_624354)
MAAPLTRTSWTVLRRNHFQYKQFLTVSCVNRFSQYKYSHQQDKKFRTSEKTVRNVLFYTIFFSGFGYVLY
KWKDDCQNRFSNLIKSMFTIYAKPVSWDGGNNRNKYNFIADVVEKSAPAVVYIEIQNNRRFDFQTGKPFN
ISNGSGFIVESDGLILTNAHVVTAKPHTTVKVRLYDGSVYTGTVEDIDVHSDLATVRINKTNLPVMKLGS
SSNLRPGEFVVAIGSPLALSNTITSGVISSVNRHSQELGLLNKQMAYIQTDAAITFGNSGGPLVNLDAEA
IGINAMKVTSGISFAIPIDYAKDFLRKAELRRKNKGTQFAMEKTKTQYIGITMLTLTPDLFYELQKKLKG
IPHNIRYGVLVYKVIVGSPAHLGGLQAGDIITQVNDEPVVSSASIYKAIEAAKILRMTVIRGLEVLHLRI
EPEEI

>Anopheles gambiae_(XP_310886)
MHCALRRPALFLQRRLLAVVQLAPHNNLRAFGGTGEHGRSDGSGEHSDSWSAQKAGLTATLALAGMFGLL
AYNTRPDQSKRKATGWPAFGFLPTVSAKTSATAGNRQQYNFIADAVEISAPAVVFIEIRDRQRVDFFTRE
PVTVSNGSGFIIERDGLILTNAHVVVSKPHTLVTVRLTDGRTFPGQVEHVDPTSDLATVRIRCDNLPTLR
LGSSADLRPGEWVVALGSPLALNNTVTAGVVSSTQRASQELGLRGKDINYIQTDAAITFGNSGGPLVNLD
GEAIGINSMKVTSGISFAIPIDHAKAFLRKIHETAGTAGGRRLSSGAPSYRRYIGITMLSLTPDILHELQ
QRNHNFPPTVRGGVLVWKVIQGSPAHSGGLQPGDIITHINGKEINSSGDVYELLAAQEKKLAITIYRGQQ
PATVHVFPEDTTA