>Homo sapiens_CHRNB3
MLPDFMLVLIVLGIPSSATTGFNSIAENEDALLRHLFQGYQKWVRPVLHSNDTIKVYFGL
KISQLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFEN
ADGRFEGSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTM
VDLILINENVDRKDFFDNGEWEILNAKGMKGNRRDGVYSYPFITYSFVLRRLPLFYTLFL
IIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYL
LFIMIFVTLSIIVTVFVINVHHRSSSTYHPMAPWVKRLFLQKLPKLLCMKDHVDRYSSPE
KEESQPVVKGKVLEKKKQKQLSDGEKVLVAFLEKAADSIRYISRHVKKEHFISQVVQDWK
FVAQVLDRIFLWLFLIVSVTGSVLIFTPALKMWLHSYH

>Callithrix jacchus_CHRNB3
MLTDFMLVLIVLGIPSSATAGFSSIAENEDALLRHLFQGYQKWVRPVLHSNDTIKVYFGL
KISQLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFEN
ADGRFEGSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTM
VDLILINENVDRKEFFDNGEWEILNAKGMKGNRRDGVYSYPFITYSFVLRRLPLFYTLFL
IIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYL
LFIMIFVTLSIIVTVFVINVHHRSSSTYQPMAPWVKRLFLQKLPKLLCMKDHVDRYSIPE
KEESQPVVKSKVLEKKKHKQLSDGEKVLVAFLEKAADSIRYISSHVKKEHFISQVVQDWK
FVAQVLDRIFLWLFLIVSVTGSVLIFTPALKMWLHSYH

>Gallus gallus_CHRNB3
MLCLMLCVLCWSRSDVAALGSVAENEDALLRHLFQGYQKWVRPVENSNDTIKVLFGLKIS
QLVDVDEKNQLMTTNVWLKQEWMDHKLSWNPEEYGGITAIRVPSESLWLPDIVLFENADG
RFEGSLMTKAIVKYNGVVTWMPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGSMVDL
ILVDENVDRKDFFDNGEWEILNAKGMKGNRKDGLYSYPFVTYSFVLRRLPLFYTLFLIIP
CLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFI
MIFVTLSIIVTVFVINVHHRSSATYHPMAPWVKRLFLQKLPRLLCMKGHVDRYSFSDTEE
KETTLKSKLPGKQKHKQAKDGEKVVIAFLEKAADSIRYISRHVKKEHFIRQVVQDWKFVA
QVLDRIFLWLFLVVSVTGSVLIFTPALQMWLNSTL

>Xenopus tropicalis_CHRNB3
TMKMFIYACTNIIFIPSGFAKFHPLAEIEDALLRKLFAGYQKWVRPVLNPNSTIKVNFGL
KISQLVDVDEKKQLMTTNVWLRQEWMDMKLRWNPKDYGGITYIRVPSESLWLPDIVLFEN
ADGRFEGSLMTKAIIKYDGTVTWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGNM
VDLILLDENVDRKDFFDNGEWDILNATGLKGMRKDGLYSYPFITYSFVLRRLPLFYTLFL
IIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYL
LFIMIFVTLSIIVTVFVINVHHRSSATYHPMAPWVKRLFLEKLPKLLCMKGHVDRFSFFD
SESDVSSAKSKPSGKRKNIHASDGEKVLIAFLEKAADSIKYISTHVKKEHFIRQVVQDWK
FVAQVLDRIFLWLFLSVSITGSVLIFTPALQMWLNSHV

>Danio rerio_CHRNB3a
MKLQISGILLVAAVAYATIEAPEEFVSLAEMEDTLLRNLFRGYQKWVRPVLHANDTITVR
FGLKISQLVDVDEKNQLMTTNVWLWEEWTDYKLRWNPEDYGGITSIRVPSETIWLPDIVL
YENADGRFEGSLMTKAIVRFNGTIMWTPPASYKSACTMDVTFFPFDRQNCSMKFGSWTYD
GTMVDLTLVDAYVDRKDFFDNGEWEILNATGQRGSRRDGIYSYPYLTYSFILKRLPLFYT
LFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIG
EYLLFIMIFVTFSIIVTVFVINVHHRSSATYHPMAPWVKSLFLQRLPRLLCMRGHTDRYQ
YPDIELRSPELKRGMKKGQQKSAGGGRAGVKEDENQAWIALLEKATHSVHYISRHIRKEH
FIREVVQDWKFVAQVLDRIFLWAFLTVSVLGTILIFTPALQMFFSTS

>Danio rerio_CHRNB3b
MTLTVIGLFTLFTSIFATTPAREFVSLAEREDALLRDLFQGYQRWVRPILHANHTVKVRF
GLKISQLVDVDEKNQLMTTNVWLYEEWLDYKLRWNPENYGGITFIRVPSESIWLPDIVLY
ENADGRFEGSIMTKAIVRYNGLITWTPPASYKSACTMDVTFFPFDRQNCSMKFGSWTYDG
NMVELVLVNHQVDRSDFFDNGEWEILSATGHKGSRRDGHYSYPYITYSFILKRLPLFYTL
FLIIPCLGLSFLTVLVFYLPSDEGEKVSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGE
YLLFIMIFVTLSIIVTVFVINVHHRSSATYHPMSPWVRTLFLQRLPDLLCMRGNTDRYHY
PQMEPQSPDLKPRSKKGPPGPEGDGQALINMLEQATNSVRYISRHIKKEHFIREVVQDWK
FVAQVLDRIFLWAFLTVSVLGTILIFTPAVKMFLSTPPPPSP

>Takifugu rubripes_CHRNB3a
PPLLSVLLSVPIPLAPAEEDFVSLAELEDSLLRNLFKGYQKWVRPVQHANDTITVRFGLK
ISQLVDVDEKNQLMTTNVWLWQEWIDVKLKWNPDDYGGITAIRVPSETIWLPDIVLYENA
DGRFEGSLMTKAIVRWDGTITWTPPASYKSACNMDVTFFPFDRQNCSMKFGSWTYDGNMV
DLVLVDHYVDRKDFFDNGEWEILNATGVKGSRRDEVYWYPFVTYSFILKRLPLFYTLFLI
IPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLL
FIMIFVTFSIIVTVFVINVHHRSSATYHPMAPWVKSLFLQRLPRLLCMRGHTDRYNFPDN
EMRSPEPKPRRAIGRRGVQGKEDENQAWLAMLEKATNSVRYISQHIRKEHFIREVVQDWK
FVAQVLDRIFLWAFLTVSILGTVLIFTPALKMYLHKMFH

>Takifugu rubripes_CHRNB3b
HLPDQLVCAKTSLSAPAQSEFVSLAEMEDALLRNLFQGYQRWVRPIQHANDTIKVRFGLK
ISQLVDVDEKNQLMTTNVWLCQEWIDFKLRWNPDKYGGITSIRVPSENLWLPDIVLYENA
DGRFEGSLMTKAIVRYNGAITWTPPASYKSACTMDVTFFPFDRQNCTMKFGSWTYDGTMV
DLILIDKQVDRKDFFDNGEWEILSATGAKGNRKDGLYSYPFITYSFILKRLPLFYTLFLI
IPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLL
FIMIFVTLSIIVTVFVINVHHRSSATYHPMSPWVRTLFLQKLPSLLCMRGHTDRYHYPEL
GPESPEPKPRSGGRRGGQRISSGGTYGQASSEGKDDEDWATMLDKAIFSVRYISRHIRKE
HFIREVVQDWKFVAQVLDRIFLWAFLTVSVLGTILIFTPALQKFMQVLP

>Tetraodon nigroviridis_CHRNB3a
LLVASVCFFPVFHMFAPAQSEFVSLAEMEDALLRNLFQGYQRWVRPIQHANDTIKVRFGL
KISQLVDVDEKNQLMTTNVWLCQEWIDYKLRWNPDKYGGITSIRVPSENLWLPDIVLYEN
ADGRFEGSLMTKAIVRYNGAITWTPPASYKSACTMDVTFFPFDRQNCTMKFGSWTYDGTM
VDLILIDKQVDRKDFFDNGEWEILSATGAKGNRKDGLYSYPFITYSFILKRLPLFYTLFL
IIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYL
LFIMIFVTLSIIVTVFVINVHHRSSATYHPMSPWVRTLFLQKLPRLLCMRGHTDRYHYPE
LGPESPEPRVRAGGRRGGQRVGSGSHGQTPPEGKDDEEWASMLDKAIYSVRYISRHIRKE
HFIREVVQDWKFVAQVLDRIFLWAFLTVSVLGTILIFTPALQKFMKVLPQSSS

>Tetraodon nigroviridis_CHRNB3b
QEDFVSLAELEDSLLRNLFRGYQKWVRPVQHANDTITVRFGLKISQLVDVDEKNQLMTTN
VWLWQEWVDVKLKWNPDDYGGITAIRVPSETIWLPDIVLYENADGRFEGSLMTKAIVRWD
GTITWTPPASYKSACTMDVTFFPFDRQNCSMKFGSWTYDGNMVDLVLVDHYVDRKDFFDN
GEWEILNATGVKGSRRDGIYWYPFVTYSFILKRLPLFYTLFLIIPCLGLSFLTVLVFYLP
SDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTFSIIVTVFVI
NVHHRSSATYHPMAPWVKSLFLQRLPRLLCMRGHTDRYHFPDMEMHSPELKPRRAVGRRG
VQGQQKGPLAGKEDENQAWLAMLEKATNSVRYISQHIRKEHFIREVVQDWKFVAQVLDRI
FLWAFLTVSILGTVLIFTPALQMYLSTP

>Gasterosteus aculeatus_CHRNB3a
QDDVVSLAEMEDSLLRNLFRGYQKWVRPVLHSNDTITVCFGLKISQLVDVDEKNQLMTTN
VWLWQEWVDLKLKWNPDDYGGITSIRVPSETIWLPDIVLYENADGRFEGSLMTKAIVRWD
GTITWTPPASYKSACTMDVTFFPFDRQNCSMKFGSWTYDGNMVDLVLVDHYVDRKDFFDN
GEWEILNATGQRGSRRDEVYWYPFVTYSFILKRLPLFYTLFLIIPCLGLSFLTVLVFYLP
SDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLHHRSSSTYHPMAPWVKSL
FLQRLPRLLCMRGHTDRYHFEDMEMHSPEVKTRRGVGRRGAPGQRGPVSGKEEENRAWLA
MLEKATSSVRYISRHIKKEHFIREVVQDWKFVAQVLDRILLWAFLTVSILGTVLIFTPAL
QMYFSTP

>Gasterosteus aculeatus_CHRNB3b
MKWTVLFLLLVCPLSLAEIHAPSEFVSLAEMEDALMRNLFQGYQRWVRPIQHANDTVRVR
FGLKISQLVDVDEKNQLMTTNVWLWQEWIDYKLRWNPDKYGGITSIRVPSEIIWLPDIVL
YENADGRFEGSLMTKAIVKFNGVITWTPPASYKSACTMDVTFFPFDRQNCTMKFGSWTYD
GHMVDLVLIDNQVDRRDFFDNGEWEILSATGARGTRKDDMYTYPFLTYSFILKRLPLFYT
LFLIFPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIG
EYLLRSSATYHPMSPWVRNLFLQKLPRFLCMRGHTDLYHYPELAPESPEMKPRSGGRKGG
QRANSGARGQTASEGKEDEAWATMLDKAVYSVRYISRHIRKEHFIREVVQDWKFVAQVLD
RIFLWAFLTVSILGTVLIFTPALYSFFKIP

>Oryzias latipes_CHRNB3a
FPLLPVQENVLSLAELEDSLLRNLFKGYQKWVRPVQHANDTITVRFGLKISQLVDVDEKN
QLMTTNVWLWQEWIDVKLKWNPDDYGGITSIRVPSETIWLPDIVLYENADGRFEGSLMTK
AIVRWDGTITWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGNMVDLVLVDHYVDR
KDFFDNGEWEILNATGQRGSRRDEMYWYPFLTYSFILKRLPLFYTLFLIIPCLGLSFLTV
LVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTFSII
VTVFVINVHHRSSATYHPMAPWVKSLFLQKLPRLLCMRGHTDRYHFPDIEMRSPELKTRR
GAGRRAVPGGMEDDSQAWLAMLEKATNSVHYISRHIRKEHFIREVVQDWKFVAQVLDRIF
LWAFLTVSILGTVLIFTPALQSYLSTP

>Oryzias latipes_CHRNB3b
LTVFLLLLLSACPQLFAAITAPKRFVSLAEMEDDLLKNLFQGYQRWVRPIQRPNDTVRVR
FGLKISQLVDVDEKNQLMTTNVWLRQEWIDYKLRWNPDKYGGITSIRVPSENIWLPDIVL
YENADGKFEGSLMTKAIVKFNGAVTWMPPASYKSACTMDVTFFPFDRQNCSMKFGSWTYD
GNMVDLVLMDSQVDRKDFFDNGEWEILSATGAKGNRKDGLYFYPFITCSFILKRLPLFYT
LFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIG
EYLLFIMIFVTLSIIVTVFVINVHHRSSATYHPMSPWVRSLFLQKLPRLLCMRGHADRYH
YPELAPESPALKSRSGGRRGIQRMSSGGQQSTYDGKEEEAYSTMLEKAIYSVRYISRHIR
KDHFIREVVQDWKFVAQVLDRIFLWIFLSVSVLGTILIFTPALQMFMKIPPPAPSE>Homo sapiens_CHRNB2(ENSP_357461)
MARRCGPVALLLGFGLLRLCSGVWGTDTEERLVEHLLDPSRYNKLIRPATNGSELVTVQL
MVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLY
NNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDR
TEIDLVLKSEVASLDDFTPSGEWDIVALPGRRNENPDDSTYVDITYDFIIRRKPLFYTIN
LIIPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKY
LMFTMVLVTFSIVTSVCVLNVHHRSPTTHTMAPWVKVVFLEKLPALLFMQQPRHHCARQR
LRLRRRQREREGAGALFFREAPGADSCTCFVNRASVQGLAGAFGAEPAPVAGPGRSGEPC
GCGLREAVDGVRFIADHMRSEDDDQSVSEDWKYVAMVIDRLFLWIFVFVCVFGTIGMFLQ
PLFQNYTTTTFLHSDHSAPSSK
>Pan troglodytes_CHRNB2(ENSPTRP_2339)
MARRCGPVALLLGFGLLRLCSGVWGTDTEERLVEHLLDPSRYNKLIRPATNGSELVTVQL
MVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLY
NNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDR
TEIDLVLKSEVASLDDFTPSGEWDIVALPGRRNENPDDSTYVDITYDFIIRRKPLFYTIN
LIIPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKY
LMFTMVLVTFSIVTSVCVLNVHHRSPTTHTMAPWVKVVFLEKLPALLFMQQPRHHCARQR
LRLRRRQREREGAGALFFREAPGADSCTCFVNRASVQGLAGAFGAEPAPVAGPGRSGEPC
GCGLREAVDGVRFIADHMRSEDDDQSVSEDWKYVAMVIDRLFLWIFVFVCVFGTIGMFLQ
PLFQNYTTTTFLHSDHSAPSSK
>Mus musculus_CHRNB2(ENSMUSP_29562)
MARCSNSMALLFSFGLLWLCSGVLGTDTEERLVEHLLDPSRYNKLIRPATNGSELVTVQL
MVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEDFDNMKKVRLPSKHIWLPDVVLY
NNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDR
TEIDLVLKSDVASLDDFTPSGEWDIIALPGRRNENPDDSTYVDITYDFIIRRKPLFYTIN
LIIPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKY
LMFTMVLVTFSIVTSVCVLNVHHRSPTTHTMAPWVKVVFLEKLPTLLFLQQPRHRCARQR
LRLRRRQREREGAGTLFFREGPAADPCTCFVNPASMQGLAGAFQAEPAAAGLGRSMGPCS
CGLREAVDGVRFIADHMRSEDDDQSVREDWKYVAMVIDRLFLWIFVFVCVFGTIGMFLQP
LFQNYTATTFLHSDHSAPSSK
>Canis familiaris_CHRNB2(ENSCAFP_25294)
MATRSGPAALLLGFGLLGLHAGVWGTDTEERLVEHLLDPSRYNKLIRPATNGSELVTVQL
MVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLY
NNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDR
TEIDLVLKSDVASLDDFTPSGEWDIVALPGRRNENPDDSTYVDITYDFIIRRKPLFYTIN
LIIPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKY
LMFTMVLVTFSIVTSVCVLNVHHRSPTTHTMAPWVKVVFLEKLPTLLFMQQPRHRCARQR
LRLRRRQREREAGALLFREAPGESYSGSARGGVGTDGCGLRSAVDGVRFIADHVRNEDDD
QSVSEDWKYVAMVIDRLFLWIFVFVCVFGTIGMFLQPLFQNYSAATFLHTDHSAPSAK
>Xenopus tropicalis_CHRNB2(ENSXETP_8352)
YISCRDFAFAFGTGCLGTDTEERLVEHLLDPSRYNKLIRPATNGSEQVTVQLMVSLAQLI
SVHEREQIMTTNVWLTQEWEDYRLTWDPAEFDDMKKVRLPSKHIWLPDVVLYNNADGMYE
VSFYSNAVVSHDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTELDLVLR
SDVASLDDFTPSGEWDIIALPGRRNENPNDSTYVDITYDFIIRRKPLFYTINLIIPCILI
TSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKYLMFTMVLV
TFSIVTSVCVLNVHHRSPTTHTMPPWVKVVFLDKLPTLLFMKQPRQNCARQRLRQQRQSQ
ERAAGSFFLRDGARSCTCYVNQASVKKYGAQLSELPEGVNGFRDRQGKVRQCLCGLQEAV
DGVRFIADHMKSEDDDQSVSEDWKYVAMVIDRLFLWIFVFVCVFGTIGMFLQPLFQNYTT
NALVHMNHAAKKMK
>Danio rerio_CHRNB2(ENSDARP_41624)
MMALWTLFCILAIVKSGYGADTEERLVEHLLNPAHYNKLIRPATNGSEVVTVQLMVSLAQ
LISVHEREQIMTTNVWLTQEWQDYRLTWSPEEFDGMKKVRLPSKHIWLPDVVLYNNADGM
YEVSFYSNAVVSYDGSVFWLPPAIYKSACKIEVKHFPFDQQNCTLSFRSWTYDRTEVDLV
LRADVASMDDFTPSGEWDIIALPGRRNENPSDPTYVDITYDFIIRRKPLFYTINLIIPCV
LITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKYLMFTMV
LVTFSIVTSVCVLNVHHRSPTTHTMPPWVKLVFLNKLPALLFMRQPRNSSERQRLRQRRR
ANEQQEGGRGGLAAGLMAGLGLSGSSSGSKENNEACTCYVNRASVKQFGAELGGGGGGGG
STDGLNGIREGGRETREGGANPLQGSALPRGKQQPPTVLTQALLAQACPGFEEAVDGVRF
IANHMKSEDDDRSVSEDWKYVAMVIDRLFLWIFVFVCVFGTIGMFLQPLFQNYTAKTITH
TPG
>Takifugu rubripes_CHRNB2(ENSTRUP_14017)
TAVLPSSLHPSIQALLFQYAWMVGSDTEERLVEHLLNPAHYNKLIRPATNGSELVTVQLM
VSLAQLISVHEREQVMTTNVWLTQEWQDYRLTWIPEEFDGMLKVRLPSKHIWLPDVVLYN
NADGVYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTLRFRSWTYDRT
EIDLVLRADVASMDDFTPSGEWDIIALPGRRNENPGDPTYVDITYDFIIRRKPLFYTINL
IIPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKYL
MFTMVLVTFSIVTSVCVLNVHHRSPTTHTMPPWVKMVFLQKLPALLFMRQPRNSCERQRL
RQRRRAQEHKEGGIFGKEDSDPCTCYVNRASVKQFGGDLGGAGGSMDGLNRARDGREAQA
CPGFEEAVEGVRFIANHMKSEDDDQSVSEDWKYVAMVIDRLFLWIFVFVCVFGTMGMFMQ
PLFQNYTAKTINSSPG
>Tetraodon nigroviridis_CHRNB2(ENSTNIP_21501)
GLCADTEERLVEHLLNPAHYNKLIRPATNGSELVTVQLMVSLAQLISVHEREQVMTTNVW
LTQEWQDYRLTWIPEEFDGMLKVRLPSKHIWLPDVVLYNNADGVYEVSFYSNAVVSYDGS
IFWLPPAIYKSACKIEVKHFPFDQQNCTLRFRSWTYDRTEIDLVLRADVASMDDFTPSGE
WDIIALPGRRNENPGDPTYVDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSDC
GEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKYLMFTMVLVTFSIVTSVCVLNVH
HRSPTTHTMPPWVKMVFLQKLPALLFMRQPRNSCERQRLRQRRRAQEQKGGGRCGEPGGL
MVGNGLGNAGGSGGGTTTGLFGKEDSDPCTCYVNRASVKQFGGDLGSAGGGSMDGLNRAR
EAREGGSGNQSRGKPGTGAPALSHALLAQACPGFEEAVEGVRFIANHMKSEDDDQSVSED
WKYVAMVIDRLFLWIFVFVCVFGTMGMFLQPLFQNYTAKTINSSPG
>Gasterosteus aculeatus_CHRNB2(ENSGACP_16024)
GLGADTEERLVEHLLNPAHYNKLIRPATNGSELVTVQLMVSLAQLISVHEREQVMTTNVW
LTQEWQDYRLTWVPEEFDGMLKVRLPSKHIWLPDVVLYNNADGVYEVSFYSNAVVSYDGS
IFWLPPAIYKSACKIEVKHFPFDQQNCTLRFRSWTYDRTEIDLVLRADVASMDDFTPSGE
WDIIALPGRRNENPADPTYVDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSDC
GEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKYLMFTMVLVTFSIVTSVCVLNVH
HRSPTTHTMPPWVKLVFLNKLPALLFMRQPRNSCERQRLRQRRRAQEQKEGGRSGEAGAL
MVGLGLGNASGNRGGTSTGVFSKEDSDPCTCYVNRASVKQFGGDLALLAQACPGFEEAVE
GVRFIANHMKSEDDDQSVSEDWKYVAMVIDRLFLWIFVFVCVFGTLGMFMQPLYQNYT
>Homo sapiens_CHRNG(ENSP_374145)
MHGGQGPLLLLLLLAVCLGAQGRNQEERLLADLMQNYDPNLRPAERDSDVVNVSLKLTLT
NLISLNEREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENNVDG
VFEVALYCNVLVSPDGCIYWLPPAIFRSACSISVTYFPFDWQNCSLIFQSQTYSTNEIDL
QLSQEDGQTIEWIFIDPEAFTENGEWAIQHRPAKMLLDPAAPAQEAGHQKVVFYLLIQRK
PLFYVINIIAPCVLISSVAILIHFLPAKAGGQKCTVAINVLLAQTVFLFLVAKKVPETSQ
AVPLISKYLTFLLVVTILIVVNAVVVLNVSLRSPHTHSMARGVRKVFLRLLPQLLRMHVR
PLAPAAVQDTQSRLQNGSSGWSITTGEEVALCLPRSELLFQQWQRQGLVAAALEKLEKGP
ELGLSQFCGSLKQAAPAIQACVEACNLIACARHQQSHFDNGNEEWFLVGRVLDRVCFLAM
LSLFICGTAGIFLMAHYNRVPALPFPGDPRPYLPSPD
>Gorilla gorilla_CHRNG(ENSGGOP_2069)
MHGGQGPLLLLLLLAVCLGAQGRNQEERLLADLMQNYDPNLRPAERDSDVVNVSLKLTLT
NLISLNEREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENNVDG
VFEVALYCNVLVSPDGCIYWLPPAIFRSACSISVTYFPFDWQNCSLIFQSQTYSTNEIDL
QLSQEDGQTIEWIFIDPEAFTENGEWAIQHRPAKMLLDPAAPAQEAGHQKVVFYLLIQRK
PLFYVINIIAPCVLISSVAILIYFLPAKAGGQKCTVAINVLLAQTVFLFLVAKKVPETSQ
AVPLISKYLTFLLVVTILIVVNAVVVLNVSLRSPHTHSMARGVRKVFLRLLPQLLRMHVR
PLAPAAVQDTQSRLQNGSSGRSITTGEEVALCLPRSELLFQQWQRQGLVAAALEKLEKGP
ELGPSQFCGSLKQAAPAIQACVEACNLIACARHQQSHFDNGNEEWFLVGRVLDRVCFLAM
LSLFVCGTAGIFLMAHYNRVPALPFPGDPHPYLPSPD
>Mus musculus_CHRNG(ENSMUSP_27470)
MQGGQRPQLLLLLLAVCLGAQSRNQEERLLADLMRNYDPHLRPAERDSDVVNVSLKLTLT
NLISLNEREEALTTNVWIEMQWCDYRLRWDPKDYEGLWILRVPSTMVWRPDIVLENNVDG
VFEVALYCNVLVSPDGCIYWLPPAIFRSSCSISVTYFPFDWQNCSLVFQSQTYSTSEINL
QLSQEDGQAIEWIFIDPEAFTENGEWAIRHRPAKMLLDSVAPAEEAGHQKVVFYLLIQRK
PLFYVINIIAPCVLISSVAILIYFLPAKAGGQKCTVATNVLLAQTVFLFLVAKKVPETSQ
AVPLISKYLTFLMVVTILIVVNSVVVLNVSLRSPHTHSMARGVRKVFLRLLPQLLRMHVR
PLAPAAVQDARFRLQNGSSSGWPIMAREEGDLCLPRSELLFRQRQRNGLVQAVLEKLENG
PEVRQSQEFCGSLKQASPAIQACVDACNLMARARRQQSHFDSGNEEWLLVGRVLDRVCFL
AMLSLFICGTAGIFLMAHYNQVPDLPFPGDPRPYLPLPD
>Xenopus tropicalis_CHRNG(ENSXETP_30553)
RGGMDTVLLLVLICISAALCHNEEEGLLNDLMKNYNKNLRPAEKDGDIVSVSIKLTLTNL
ISLNEREEALTTNVWVEVQWRDYRLSWDPNEYYGISMMRIPSTSVWLPDVGLENNVDGTF
DIALYANTLVSSDGSMYWLPPAIYRSSCPVVVTYFPFDWQNCSMVFQSQTYSANEIELLL
TVDEQTIEWIEIDPEAFTENGEWAIKHMPAKKIINHRLTPDDLNYQQIVFYLIIQRKPLF
YIINIIVPCVLISFVSILVYFLPAKAGGQKCTVSINILLAQTVFLFLIAQKIPETSTAVP
LIVKYLTFLMVVTITIVANAVIVLNISLRTPNTHSMSSTVRELCLRTVPRLLRMHLRPSD
AAPPLAPLMRRSSSVGLMIKADEYMLRKPRSQLMFEKQKERDGLMKVVLDKIGRGMENNT
SDDLVHSLKHAAPEIRACVEACCHIASATREKNEFKSTGDNDWKCQSKVL
>Danio rerio_CHRNG(ENSDARP_110378)
MDQNLSSKIIWLWILLFRFSGALCNLEGSLHRDLMVGYNKNIRPVESHEDIIDVKIKMTL
TNLISLNEKEETLTTCVWIEMQWRDYRLRWANRTGFEVYENITRMRLPSKTIWLPDIGLE
NNVDGRFEVALYANTLIDPDGSVYWLPPAIYRSSCAIKVNYFPFDWQNCSMVFRSQTYNS
NEITLMLSDEDNVTMEWIEIDPEAFTENGEWMIKHRPAKKVINKRYRPDELEHQEIIFFL
IIQRKPLFYVINIIVPCVLFSSLGLLVYFLPAKAGGQKCTMTICILLGQTVFLFLIAKKV
PETSQAVPLIGKYLMFVMSVTTITVMNCVVVLNVSLRTPNTHPMSNTIRKVLLNILPRVL
RMTMQRWTPEQEEGDFKMFALGNGTPLRRRRRSSLGLIAKADEYMFRTARSELMFSRLKE
RKGLLKNTLEKIQNGLGGNTAQDLECSLAAASPEVQQCVSSCKHIAESTKHQNDFQSKNE
EWFLVARVIDRMCFFVMALLFILGTIGIFLTGHFNQAPSQPFPGDPKKYLPEISAGDIPG
>Takifugu rubripes_CHRNG(ENSTRUP_36755)
MDSGCPLSLSLFIRVFMISAAASAVNLEGELFKDLMKGYNKNVRPTEKSGDITQVDIKLT
LTNLISLNEKEEALTTSVWIELQWCDYRLRWDQPPRSTLYGNITKPLRIPSKILWLPDII
LENNVDGQFEVALYCNALVSPDGCVYWLPPAIYRSACPITVNYFPFDWQNCTMVFRSQTY
SANEIDMVLKVEDNHTLEWVDIDPEAFTENGEWAIKHRPAKKVINSQYTKDDREYQEVIF
FLIIQRKPLFYIINIIAPCVLFSSLCLLVYYLPAKAGGQKCTMSVATLLGQTVFLFLIAK
KVPETSKAVPLIAKYLMFVMSVTTMVVMNCVIVLNVSLRTPSTHIMTDAVRKVLLNILPR
LLKMQMRPWTPNNDSTPEIRNRRRSSMTLITKAEEYAMKTARSELMFSRLKERNGLMKSV
LEKLHDGLDGGTPEQLGISLAKASPEVKKCVASCKHIAETARQQSNFQNENEEWFLVARV
IDRACFIVMASVFFIGTIGVFLMGHFNQPPSAPFPRDAKTYLPPIN
>Tetraodon nigroviridis_CHRNG(ENSTNIP_1763)
SGCRLSLSFFVTVFTISAAASAVNLERELFKDLMKGYNKHVRPTEKSGDITQVDIKMTLT
NLISLNEKEEALTTSVWIELQWCDYRLRWDQPPRAALYGNITKPLRIPSRIIWLPDIILE
NNVDGQFEVALYCNALVSPDGCVYWLPPAIYRSACPITVNYFPFDWQNCTMVFRSQTYSA
NEINMVLKVEDNHTLEWVDIDPEAFTENGEWAIKHRPAKKVINRQYTKDDQEYQEVIFFL
IIQRKPLFYIINIIVPCVLFSSLCLLVYYLPAKAGGQKCTMSIATLLGQTVFLFLIAKKV
PETSKAMPLIAKYLMFVMSVTTMVVMNCVIVLNVSLRTPSTHIMTDTVRKILLNILPRLL
KMRMRPWTPNKDSAFPCRRRSSMTLITKAEEYVMKTARSELMFSRLKERNGLMKSVLEKL
HEGLDGGTPEQLSISLAKASPEVKKCVASCKHIAETARQHNNFQNENEEWFLVARVIDRV
CFIVMASVFFIGTMGVFLMGHFNQPPSTPFPGDVKMYLPP
>Gasterosteus aculeatus_CHRNG(ENSGACP_19898)
VIHILTIFICIEKTSAINLEGELFKDLMKGYNKNVRPMENGSDVTQVAIKMTLTNLISLN
EKEEALTTGVWIGMQWCDYRLRWDRPPRSALYGSITSQLRLPSKSIWLPDIILENNVDGN
FEVALYCNALVSPNGCVNWLPPAIYRSACAITVNYFPFDWQNCTMVFHSQTYSANEIKLV
LTEEDDLTLEWVDIDPEAFTENGEWAIKHRPAKKLINTDYNKDELEYQEVVFFLIIQRKP
LFYVINIIAPCVLFSSLGLLVYFLPAKAGGQKCTMSIATLLGQTVFLFLIAKKVPETSRA
VPLIGKYLMFVMSVTTMVVMNCVIVLNVSLRTPNTHKMTDKVRKILLNILPRLLNMQMRP
WTPDGDNADTRRRSSMTLITKAEEYAMKTARSELMFAALKERNGLMRSVLEKLKDELEGG
TAEQLSASLGKASSQLQQCVSSCKHIAKTARQQNNFKKENEEWFLVAKVIDRVCFIVMVS
VFFIGTIGIFLTGHFNQPPSSPFLGDPKTYLPPTNNLTDRVENGR
>Homo sapiens_CHRND(ENSP_258385)
MEGPVLTLGLLAALAVCGSWGLNEEERLIRHLFQEKGYNKELRPVAHKEESVDVALALTL
SNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMVWLPEIVLENNND
GSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLKFSSLKYTAKEIT
LSLKQDAKENRTYPVEWIIIDPEGFTENGEWEIVHRPARVNVDPRAPLDSPSRQDITFYL
IIRRKPLFYIINILVPCVLISFMVNLVFYLPADSGEKTSVAISVLLAQSVFLLLISKRLP
ATSMAIPLIGKFLLFGMVLVTMVVVICVIVLNIHFRTPSTHVLSEGVKKLFLETLPELLH
MSRPAEDGPSPGALVRRSSSLGYISKAEEYFLLKSRSDLMFEKQSERHGLARRLTTARRP
PASSEQAQQELFNELKPAVDGANFIVNHMRDQNNYNEEKDSWNRVARTVDRLCLFVVTPV
MVVGTAWIFLQGVYNQPPPQPFPGDPYSYNVQDKRFI
>Mus musculus_CHRND(ENSMUSP_72983)
MAGPVLTLGLLAALVVCALPGSWGLNEEQRLIQHLFNEKGYDKDLRPVARKEDKVDVALS
LTLSNLISLKEVEETLTTNVWIDHAWVDSRLQWDANDFGNITVLRLPPDMVWLPEIVLEN
NNDGSFQISYACNVLVYDSGYVTWLPPAIFRSSCPISVTYFPFDWQNCSLKFSSLKYTAK
EITLSLKQEEENNRSYPIEWIIIDPEGFTENGEWEIVHRAAKLNVDPSVPMDSTNHQDVT
FYLIIRRKPLFYIINILVPCVLISFMINLVFYLPGDCGEKTSVAISVLLAQSVFLLLISK
RLPATSMAIPLVGKFLLFGMVLVTMVVVICVIVLNIHFRTPSTHVLSEGVKKFFLETLPK
LLHMSRPAEEDPGPRALIRRSSSLGYICKAEEYFSLKSRSDLMFEKQSERHGLARRLTTA
RRPPASSEQVQQELFNEMKPAVDGANFIVNHMRDQNSYNEEKDNWNQVARTVDRLCLFVV
TPVMVVGTAWIFLQGVYNQPPLQPFPGDPFSYSEQDKRFI
>Felis catus_CHRND(ENSFCAP_5273)
TARTPSWGVAGSPQLSPAPWPGRISRQPPSRSPLPAPHPSSCPSPGSWGLNEEERLIRHL
FEEKGYNKELRPVAHKDESVEVSLALTLSNLISLKEVEETLTTNVWMEHGWTDPRLQWDA
EEFGNISVLRLPPDMLWLPEIVLENNNDGSFQISYACNVLVYPSGYVYWLPPAIFRSSCP
ISVTYFPFDWQNCSLKFSSLKYTAKEITLSLKQEEKEGRSYPVEWIVIDPAGFTENGEWE
IVHRPARINVDPSVPLDSPGHQDVTFYLIIRRKPLFYIINILVPCVLISFMINLVFYLPA
DSGEKTSMAISVLLAQSVFLLLISKRLPATSMAIPLIGKFLLFGMVLVTMVVVICVIVLN
IHFRTPSTHVLSEGVKKLFLETLPKRLHMSRPAEDGPSPGALVRRSSSLGYISKAEEYFL
LKSRSDLMFEKQSERHGLARRLTTARRPPAGSEQAQQELFSQLKPAVDGANFIVNHMRDQ
NNYNEEKDCWNRVARTVDRLCLFVVTPIMVVGTAWIFLQGAYNQPPPQPFPGDPFSYHEK
DKRFA
>Xenopus tropicalis_CHRND(ENSXETP_30556)
HAWLWLFDLLCILVLVPGCLSESEEERLLNHIFGERGYRKELRPVEHTGETVNVSLALTL
SNLISLKEADETLTTNVWVELGWYDKRLAWDMEEFHHINIIRVPPDMVWQPQLILENNNN
GVFEVAYYSNVLVNSDGFMYWLPPAIFQTSCSINVNYFPFDWQNCSLKFSSLTYNAKEIN
LQLRQDQDEESQRNYPVEWIIIDPEGFTENGEWEIVHIPAKKNIDRSLTPESTKYQDITF
YLIIKRKPLFYIINILAPCVLIALMANLVFYLPADSGEKMTLAISVLLAQSVFLLLISQR
LPETSFAIPLISKYLMFIMVLVTIVVVSCVIVLNLHFRTPSTHVITERMKEIFLNKLPRI
LHMSRPAEPEPEPWSGVLLRRSSSVGYIVKAEEYYSVKSRSELMFEKQSERHGLTSRATP
ARVNPLNSNNSQDQLYGEIKPAIDGANFIVKHMRDKNDYNEEKDNWYRIARTVDRLCLFL
VTPVMIIGTLWIFLGGAYNLPPSLPFPGDPFDYNKEHKRLI
>Tetraodon nigroviridis_CHRNDa(ENSTNIP_8045)
ARGCNLSRGRNSAMHLRVCVCVSGCWCRNEEERLIHHLFKELGYNKELRPVRRHEDAVDV
QLALTLSNLISLKEVDETLLTNVWIEHTWTDYRLSWNLSAFDGISMLRLPSNMVWLPEIV
LENNNDAQFKVAYYSNVLVSSDGLCYWLPPAIFRSSCSISVKYFPFDWQNCTLKFTSLTY
NAKEIRMLLKEDALNGTAYTVEWIVIDPASFTENGEWEIIHRPAKRNTYKHIPMESNKHQ
DITFYLVIRRKPLFYVVNIIIPCVLISFLALLVYYLPADSGEKMTLSISVLLAQSVFLLL
ISQRLPETSMSVPLIVKYLMFIMVGVTVVVLNCVVVLNLHFRTPSTHVMSGWTKRLFLER
LPRLLRMSRPAETEAYWDGVLPRRSSSVGYIASAEEYYSVKSRSELMFEKQSERHGLVTR
VTHAAMKPQDEGGVTDQLYAEIKPAVDGANYIIKHMRNKNDYNEEKDNWSGIARTVDRLC
LFLVTPLMTVGTVIIFTGICNQPPHLPFKGDPHDYREENPRLL
>Tetraodon nigroviridis_CHRNDb(ENSTNIP_913)
GCWCRNEEERLIHHLFKELGYNKELRPVRRHEDAVDVQLALTLSNLISLKEVDETLLTNV
WIEHTWTDYRLSWNLSAFDGISMLRLPSNMVWLPEIVLENNNDAQFKVAYYSNVLVSSDG
LCYWLPPAIFRSSCSISVKYFPFDWQNCTLKFTSLTYNAKEIRMLLKEDALNGTAYTVEW
IVIDPASFTENGEWEIIHRPAKRNTYKHIPMESNKHQDITFYLVIRRKPLFYVVNIIIPC
VLISFLALLVYYLPADSGEKMTLSISVLLAQSVFLLLISQRLQKHPCLFLSSYLMFIMVG
VTVVVLNCVVVLNLHFRTPSTHVMSGWTKRLFLERLPRLLRMSRPAETEAYWDGVLPRRS
SSVGYIASAEEYYSVKSRSELMFEKQSERHGLVTRGRSDRSAVRRDQAGCGRSNYIIKHM
RNKNDYNEEKDNWSGIARTVDRLCLFLVTPLMTVGTVIIFTGICNQPPHLPFKGDPHDYR
EENPRLL
>Homo sapiens_CHRNA1(ENSP_261007)
MEPWPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQL
INVDEVNQIVTTNVRLKQGDMVDLPRPSCVTLGVPLFSHLQNEQWVDYNLKWNPDDYGGV
KKIHIPSEKIWRPDLVLYNNADGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHF
PFDEQNCSMKLGTWTYDGSVVAINPESDQPDLSNFMESGEWVIKESRGWKHSVTYSCCPD
TPYLDITYHFVMQRLPLYFIVNVIIPCLLFSFLTGLVFYLPTDSGEKMTLSISVLLSLTV
FLLVIVELIPSTSSAVPLIGKYMLFTMVFVIASIIITVIVINTHHRSPSTHVMPNWVRKV
FIDTIPNIMFFSTMKRPSREKQDKKIFTEDIDISDISGKPGPPPMGFHSPLIKHPEVKSA
IEGIKYIAETMKSDQESNNAAAEWKYVAMVMDHILLGVFMLVCIIGTLAVFAGRLIELNQ
QG
>Pan troglodytes_CHRNA1(ENSPTRP_21633)
MEPWPLLLLFSFCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQL
INVDEVNQIVTTNVRLKQGDMVDLPRPSCVILGVPLFSHLQNEQWVDYNLKWNPDDYGGV
KKIHIPSEKIWRPDLVLYNNADGDFAIVKFTKVLLEYTGHITWTPPAIFKSYCEIIVTHF
PFDEQNCSMKLGTWTYDGSVVAINPESDQPDLSNFMESGEWVIKESRGWKHSVTYSCCPD
TPYLDITYHFVMQRLPLYFIVNVIIPCLLFSFLTGLVFYLPTDSGEKMTLSISVLLSLTV
FLLVIVELIPSTSSAVPLIGKYMLFTMVFVIASIIITVIIINTHHRSPSTHVMPNWVRKV
FIDTIPNIMFFSTMKRPSREKQDKKIFTEDIDISDISGKPGPPPMGFHSPLIKHPEVKSA
IEGIKSTTVTMKSDQESNYAAAEWKYVAMVMDHILLGVFMLVCIIGTLAVFAGRLIELNQ
QG
>Felis catus_CHRNA1(ENSFCAP_13080)
MRVFVEGGEQNLTVCVSFAVSAGLVLGSEHETRLVAKLFEDYNSVVRPVEDHRQAVEVTV
GLQLIQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPEDYGGVKKIHVPSEKIWRPDFVLY
NNADGDFAIVKFTKVLLDYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDG
SVVAINPESDQPDLSNFMESGEWVIKESRGWKHWVFYACCPTTPYLDITYHFVMQRLPLY
FIVNVIIPCLLFSFLTGLVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPL
IGKYMLFTMVFVIASIIITVIVINTHHRSPSTHVMPNWVRKVFIDTIPNIMFFSTMKRPS
REKQDKKIFTEDIDISDISGKPGPPPMGFHSPLIKHPEVKSAIEGVKYIAETMKSDQESN
NAAEEWKYVAMVMDHILLGVFMLVCIIGTLAVFAERMKTMVRITPPAPQS
>Anolis carolinensis_CHRNA1(ENSACAP_5260)
MDVCCLPLLLLLGPAVLVRCSSHETRLVSDLFSKYNKVVRPVSNHRDPVRVTVGLQLIQL
INVDEVNQIVTTNVRLKQQWMDVNLKWNPEDYGGVKQIRIPSEDIWRPDLVLYNNADGDF
AINKFTKILLNYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGTMVVINP
ESDRPDLSNYMGSGEWIMKDYRGWKHEVTYACCPDLPYLDITYHFVMLRLPLYFIVNVII
PCLLFSFLTGLVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYMLF
TMVFVIASIIITVIVINTHHRNPSTHTMPQWVRKIFIDTIPNLMFFSTMKRPSKNKQEKK
IFSEDIDISEISGKQGPATVNFQSSLIKNPEVKSAIEGIKYIAETMKSDQESNNAAEEWK
FVAMVVDHLLLGIFMSVCIIGTLAVFAGRLIELHQQG
>Danio rerio_CHRNA1(ENSDARP_21860)
MNYFILILPILPYLYGPAVCSEDETRLVKTLFTGYNKVVRPVSHFKDPVVVTVGLQLIQL
ISVDEVNQIVTSNVRLKQQWKDVHLQWNPDDYGGIRKIRIPSTDLWKPDLVLYNNADGDF
AIVHETKVLLEHTGMITWTPPAIFKSYCEIVVLHFPFDLQNCSMKLGTWTYDGNLVIINP
DSDRPDLSNFMESGEWVMKDYRSWKHWVYYACCPDTPYLDITYHFLLLRLPLYFIVNVII
PCMLFSFLTGLVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYMLF
TMIFVIASIIITVIVINTHHRSPSTHIMPAWVRKIFIDTIPNMMFFSTMKRPSQERQEKR
LFPADFDISDISGKPMPASVTYHSPITKNPDVRSAIEGVKYIADTMKSDEESNNAAEEWK
FVAMVLDHILLCVFMAVCIIGTLGVFAGRLIELSML
>Takifugu rubripes_CHRNA1(ENSTRUP_21949)
LHLCDFSSGVETLAGTCASEDETRLVKTLFTGYNKVVRPVNHFSEPVVVTVGLQLIQLIS
VDEVNQIVTSNVRLRQQWVDVNLNWNPDDYGGIRKIRVPSTDIWKPDLVLYNNADGDFAI
IHETKVLLEHTGKIIWNPPAIFKSYCEIIVLHFPFDLQNCSMKLGTWTYDGLLVVINPDS
DRPDLSNFMESGEWVLKDYRSWKHWVYYTCCPDTPYLDITYHFLMLRLPLYFIVNVIIPC
MLFSFLTGLVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYMLFTM
VFVIASIIITVIVINTHHRSPSTHTMPPWIRKVFIETIPNMMFFSTMKRPSQEIRQKRLF
PTDMDISDISGNPTPTSVTYQSPIVKNPDVRSAIEGVKYIAETMKSDEESNNAAEEWKFV
AMVLDHILLCVFMAVCIIGTLAVFAGRLIELN
>Tetraodon nigroviridis_CHRNA1a(ENSTNIP_12737)
FTLRVSGGSLWFRAHLPERSQHFSRSPVLCSEDETRLVKTLFTGYNKVVRPVNHFSEPVV
VTVGLQLIQLINVDEVSQIVTSNVRLRQQWVDVNLNWNPDDYGGIRKIRVPSSEIWKPDL
VLYNNADGDFAIIHETKVLLEHTGKIIWNPPAIFKSYCEIIVLHFPFDVQNCSMKLGTWT
YDGLLVVINPDSDRPDLSNFMESGEWVLKDYRSWKHWVYYTCCGDTPYLDITYHFLMQRL
PLYFIVNVIIPCMLFSFLTGLVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTSSA
VPLIGKYMLFTMVFVIASIIITVIVINTHHRSPSTHTMPPWIRKVFIETIPNMMFFSTMK
CPSQEIRQKRLFPTDMDISDISGNPTPTSVTYQSPIVKNPDVRSAIEGVKYIAETMKADE
ESNNAAEEWKFVAMVLDHILLCVFMAVCIIGTVAVFAGRLIELNMP
>Tetraodon nigroviridis_CHRNA1b(ENSTNIP_20072)
MNTTLFSFHIILLAGAAWASSNETRLVKNLFAGYNKVVRPVTHFKDPVVVTVGLQLIQLI
NVDEVNQIVSSNVRLKQQWKDVNLHWNPDDYGGIKKIRVPSTDIWRPDLVLYNNADGDFA
IVHETKVLLEHTGMITWNPPAIFKSYCEIIVLHFPFDLQNCSMKLGTWTYDGNLVVVNPD
SDRPDLSNFMESGEWVMKDYRGWKHWVYYACCPDTPYLDITYHFLMLRLPLYFIVNVIIP
CMLFSFLTGLVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYMLFT
MVFVIASIIITVIVINTHHRSPSTHTMPDWVRRIFIETIPNIMFFSTMKRPGKEKQRKGI
QPPDFDISEISGNQATAVPYETRITKNPDVRSAIEGVKYIAETMKSDEESNNAAEEWKFV
AMVLDHILLCVFMAVCLVGTLGVFAGRLIELSML
>Gasterosteus aculeatus_CHRNA1a(ENSGACP_15736)
PVSCSEAETRLVKKLFTGYSKVVRPVDHFSDAVVVSVGLQLIQLISVDEVNQIVTSNVRL
KQRWRDVNLNWDPDDYGGIRKIRVPSTDIWKPDLVLYNNADGDFAIIHQTKVLLEHTGMI
TWNPPAIFKSYCEIIVLHFPFDLQNCSMKLGTWTYDGLLVVINPDSARPDLSNFMESGEW
VLKDYRSWKHTVNYSCCPNKPYLDITYHFLMLRLPLYFIVNVIIPCMLFSFLTGLVFYLP
TDSGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYMLFTMVFVIASIIITVIVI
NTHHRSPSTHTMPAWIRKVFIETIPNMMFFSTMKRPSLEIRQMRMFPTDMDISDISGNPA
PTSDTYVSPITKNPDVRRAIEGVKYIAETMKSDEESNNAAEEWKFVAMVLDHILLCVFMA
VCIIGTLAVFAGRLIELNTL
>Gasterosteus aculeatus_CHRNA1b(ENSGACP_6143)
MARMKPVFFIFYLVILAGAAWGSSDETRLVKTLFTGYNKVVRPVNHFKDPVVVTVGLQLI
QLISVDEVNQIVSSNVRLKQQWKDVNLQWKPEDYSGIKKIRVPSTDIWRPDLVLYNNADG
DFAIVHETKVLLEHTGMITWNPPAIFKSYCEIIVLHFPFDLQNCSMKLGTWTYDGNLVVV
NPDSERPDLSNFMESGEWVMKDFRGWKHWVYYACCPDTPYLDITYHFLMLRLPLYFIVNV
IIPCMLFSFLTGLVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYM
LFTMVFVIASIIITVIVINTHHRSPSTHTMPNWVRTVFIETIPNIMFFSTMKRPGKEKQA
KSSIYGADFDISDISGNQTTSITYQSPITKNPDVRSAIEGVKYIAETMKSDEESNNAAEE
WKFVAMVLDHILLCVFMAVCLIGTLGVFAGRLIELSML
>Oryzias latipes_CHRNA1a(ENSORLP_1705)
LGFTMYKYILKVLILFSDCCSRSVLGSEYETRLVKTLFTGYNKVVRPVTHFSQAVEVTVG
LQLIQLISVDEVNQIVTSNVRVKQQWTDVNLKWNPDDYGGIKKIRVPSTDIWKPDLVLYN
NADGDFAIIHETKVLLEYSGKITWNPPAIFKSYCEIIVLHFPFDLQNCSMKLGIWSYDGL
LVVINPESDKPDLSNFMESGEWVLKDSRCWKHWVQYTCCQDTPYLDITYHFLMLRLPLYF
IVNVIIPCLLFSFLTALVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLI
GKYMLFTMVFVIASIIITVIVINVHHRSPSTHTMPQWIRKVFIETIPNMMVFSTMKRPGQ
EIRQRRFFPTDMDISDISGNLPPTSITYQSPIIKNPDVRSAIEGVKHIAETMKLDEESNN
AAEEWKFVAMVLDHILLCVFMGVCIIGTVAVFAGRLIELNM
>Oryzias latipes_CHRNA1b(ENSORLP_21899)
MGTLFFAFQVIILAGAAFASSDETRLVKTLFTGYNKVVRPVNHYKDPVVVTVGLQLIQLI
SVDEVNQIVSSNVRLKQQWKDVNLQWNPEDYGGIRKIRVPSTDIWRPDLVLYNNADGDFA
IVHETKVLLEHTGMITWNPPAIFKSYCEIIVLHFPFDLQNCTMKLGTWTYDGNLVVVNPD
SDRPDLSNFMESGEWVMKDYRGWKHWVYYACCQDTPYLDITYHFLMLRLPLYFIVNVIIP
CMLFSFLTGLVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYMLFT
MVFVIASIIITVIVINTHHRSPSTHTMPDWVRKVFIETIPNLMFFSTMKRPAKEKQNKPV
YTAEFDISEISGNQATAVHYQSPLTKNPDVRSAIEGVKYIAETMKSDEESNNAAEEWKFV
AMVLDHILLCVFMGVCLIGTLGVFAGRLIELSTY
>Homo sapiens_CHRNA2(ENSP_385026)
MGPSCPVFLSFTKLSLWWLLLTPAGGEEAKRPPPRAPGDPLSSPSPTALPQGGSHTETED
RLFKHLFRGYNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKL
RWNPTDFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGTVHWVPPAIYK
SSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMEQTVDLKDYWESGEWAIVNATGTY
NSKKYDCCAEIYPDVTYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLC
ISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTH
TMPHWVRGALLGCVPRWLLMNRPPPPVELCHPLRLKLSPSYHWLESNVDAEEREVVVEEE
DRWACAGHVAPSVGTLCSHGHLHSGASGPKAEALLQEGELLLSPHMQKALEGVHYIADHL
RSEDADSSVKEDWKYVAMVIDRIFLWLFIIVCFLGTIGLFLPPFLAGMI
>Macaca mulatta_CHRNA2(ENSMMUP_28337)
MGPSRPAFLSFTKLSLWWLLLTPAGGEEAKRPPPRAPGDPLSSPSPTALPQGGSHTQAED
RLFKHLFRGYNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKL
RWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGTVHWVPPAIYK
SSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMEQTVDLKDYWESGEWAIVNATGTY
NSKKYDCCAEIYPDVTYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLC
ISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTH
TMPRWVRGALLGCVPRWLLMNRPLPSLELCHPPGLKLSPSYHWLETNMDAEEREVVVEEE
DRWACAGHVASSVGTLCSHGHLHSGASGPKAEAVLQEGELLLSPRMQKALEGVHYIADHL
RSEDADSSVKEDWKYVAMVIDRIFLWLFIIVCFLGTIGLFLPPFLAGMI
>Mus musculus_CHRNA2(ENSMUSP_22620)
MAPSHPAFQFWIHLYLWCLLLMPAVLAQQGSHTHAEDRLFKHLFGGYNRWARPVPNTSDV
VIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWDPAEFGNITSLRVPSEMIWIP
DIVLYNNADGEFAVTHMTKAHLFFTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGS
WTYDKAKIDLEQMERTVDLKDYWESGEWAIINATGTYNSKKYDCCAEIYPDVTYYFVIRR
LPLFYTINLIIPCLLISCLTVLVFYLPSECGEKITLCISVLLSLTVFLLLITEIIPSTSL
VIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHNMPNWVRVALLGRVPRWLMMNRP
LPPMELHGSPGLKLSPTYHWLETNMDAEEREETEEEEEEEEDENICMCAGLPDSSMGVLY
GHGSLHLRAMGPEAKTPSQASEILLSPQIQKALEGVHYIADHLRSEDADSSVKEDWKYVA
MVVDRIFLWLFIIVCFLGTIGLFLPPFLAGMI
>Felis catus_CHRNA2(ENSFCAP_17705)
MGPSRSAVLSAMRLGLWWLLLSPADLMGEGPKHPPPWTPGDPTLPSCPQGASRTQAEDRL
FKHLFRGYNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLHW
NPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGTVHWVPPAIYKSS
CSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQTEQTVDLKDYWESGEWAIINATGTYNT
KKYDCCAEIYPDVTYYFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCIS
VLLSLTVFLLLITDIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPRTHTM
PHWVRVAFLGCVPRWLLMNRPVPPLEPRDPPDLKPSSSHYWLETNVDAEEREEEKEEEDR
WGWAAHVSPSMGVLHGHGGLHQGASGPRVEVQLQEGGLLLSPRIQKALEGVHYIADHLRS
EDADSSVKEDWKYVAMVIDRIFLWLFIIVCFLGTIGLFLPPFLAGMI
>Monodelphis domestica_CHRNA2(ENSMODP_19892)
LTMPPPPLKMSDVDVFVLRHASHALDEDRLFKKLFRGYNRWSRPVQNSSDVVIIRFGLSI
AQLIDVDEKNQMMTTNVWLKQEWSDYKLRWNPTDYGNITSIRVPSELIWIPDIVLYNNAD
GEFIVTHMTKAHLFFTGTVKWAPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKID
LEQMEQMVDLKDYWESGEWAIINAVGTYNTKKYDCCVEIYPDITYFFIIRRLPLFYTINL
IIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYL
LFTMIFVTLSIVITVFVLNVHHRSPGTHNMPHWVRVAFLGCIPRWLWMNRPLPVLEFHDN
PGQKLSSTHHWLDTNVDEDKKSEENWEFSGHSSPVIDTLYHHCGHHHESPCFKAGTQLPE
TEFLLPPSIQKALEGVHYIADHLRTEDADFSVKEDWKYVAMVIDRIFLWMFIIICFLGTI
GLFLPPLLA
>Danio rerio_CHRNA2a(ENSDARP_28704)
MAENRIKTLLNNLWMLILIADHVQPVLSDGWIHAHAEDKLFHKLFIGYNKWSRPVRNISD
VVIVKFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWNPSEFDNVTSIRVPSEMIWV
PDIVLYNNADGEFAVTHMTKAHLFHTGKVSWVPPAIYKSSCSIDVTFFPFDQQNCKMKFG
SWTYDKAKIDLEQIEGTVDLKDYWESGEWAIINAVGTYNTKKYDCCHEIYPDITYFFIIR
RLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTS
LVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHSMPRWVHSVFLDHIPRWLFMRR
PEPEKKPKKTANLSTSKSWFQQETGVDGLVCQDMEFGIGLSTSISSPSATSLHLSDSEPL
LQKYELQHLGHVVNLCQHPAKLGNLVSEPGLLFSPCVLRALEGVRYIADHLRAEDEDFSV
KEDWKYVAMVIDRIFLWMFIIVCLLGTIGLFLPPWLSGMI
>Danio rerio_CHRNA2b(ENSDARP_119522)
MASFTNQLVFLRITLLCTIICESISCCEKTHSHAEDELFKKLFDGYNKWSRPVPNTSDVV
IVKFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWKPSDYDNVTSIRVPSELIWVPD
IVLYNNADGEFAVTHMTKAHLFHTGKVRWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSW
TYDKAKIDLERIENTVDLKDYWESGEWAIINAVGTYNTKKYDCCHEIYPDITYFFIIRRL
PLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTSLV
IPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHKMPCWVHSVFLDLIPRWLFMRRPA
PDSRRRQKLLLLQRQVPGMTARPANASLSTSTSWFRGQNSGEDESCRHFSYKDLELGTLS
SAISLSLQASSPCPLGLTPPPLQKFGPAPRLEVGTASRQLSGRANVTKRLDNMIPHDNPG
FPLSPSVLQALEGVHYIADHLRAEDADFSVKEDWKYVAMVIDRIFLWMFIIVCLLGTIGL
FLPPWLAGMI
>Takifugu rubripes_CHRNA2(ENSTRUP_19923)
MKKLQSFTLCFTCHLIVLCIRSVSAVLCSQKTHSHAEDDLFKKLFAGYNKYSRPVPNVTD
VVIVKFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWRPSDYDNVTSIRVPSELIWV
PDIVLYNNADGEFAVTHMTKAHLFYNGKILWVPPAIYKSSCSIDVTFFPFDQQNCKMKFG
SWTYDKAKIDLERIENTVDLNNYWESGEWAIINAVGTYNTKKYDCCHEIYPDITYFFIIR
RLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTS
LVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHKMPRWVHSVFLDLIPRWLFMRR
PAPDGRRRRLLLLQQEVMAERRRGRLTGYKSGNYLSTSANWLMDGSLSDEPNRNSYEDLE
LGRARITAQRLTKADSTVSDSSFLLSPSIIRALEGVHYIADHLRAEDADFSVKEDWKYVA
MVIDRIFLWMFIIVCLLGTIGLFLPPWLAGMI
>Tetraodon nigroviridis_CHRNA2(ENSTNIP_22729)
VLCSQKMHSHSEDALFKKLFAGYNKYSRPVPNVTDVVIVKFGLSIAQLIDVDEKNQMMTT
NVWLKQEWNDYKLRWRPSDYDNVTSIRVPSELIWVPDIVLYNNADGEFAVTHMTKAHLFH
NGKIRWVPPAIYNSSCIIDVTFFPFDQHTARCKFGPCRYDKAKLTCYWESGEWAIINAVG
TYNTKKYDCCHEIYPDITYFFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKIT
LCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPS
THKMPRWVHSVFLDLIPRWLFMRRPAPEGRRRRLLLLQQPPSPRPLGTSPPRQQNSQKKQ
EVPAGTNQQLSGARTTAQRLTKADSTGSDSYFLLSPSIIRALEGVHYIADHLRAEDADFS
VKEDWKYVAMVIDRIFLWMFIIVCLLGTIGLFLPPWLAGMI
>Gasterosteus aculeatus_CHRNA2(ENSGACP_14086)
YTIKYEPLRMILFNVSAVLCHEKSHSHAEDDLFKTLFAGYNKWSRPVSNISDVVIVKFGL
SIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWKPSDYDNVTSIRVPSELIWVPDIVLYNN
ADGEFAVTHMTKAHLFHNGKVRWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAK
IDLERTENTVDLNNYWESGEWAIINAVGTYNTKKYDCCHEIYPDITYFFIIRRLPLFYTI
NLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGE
YLLFTMIFVTLSIVITVFVLNVHHRSPSTHKMPHWVHSVFLNLIPRWLFMRRPAPDVRRR
RLALMQQDAALVRRQGRAGGYKRPSNCLSTSATWSGGSRVNLTQRAVKADNAVSDSTFLL
SPSVIRALEGVHYIADHLRAEDADFSVKEDWKYVAMVIDRIFLWMFIIVCLLGTIGLFLP
PWLA
>Oryzias latipes_CHRNA2(ENSORLP_11046)
FCYDKSHAHAEEELFQTLFTGYNKWSRPVPNISDVVIVKFGLSIAQLIDVDEKNQMMTTN
VWLKQEWNDYKLRWKPSDYDNVTSIRVPSELIWVPDIVLYNNADGEFAVTHMTKAHLFHT
GKVRWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLERIENTVDLNNYWES
GEWAIINAVGTYNTKKYDCCHEIYPDITYFFIIRRLPLFYTINLIIPCLLISCLTVLVFY
LPSDCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVF
VLNVHHRSPSTHKMPRWVHTVFLDLIPRWLFMRRPAPNGRRRRLLLLQQDGALGRLQPRV
SALDISTSSTWLREGAVLEKTERSCYEDLELGTLQSYFSFRPPSPRPPGQTPPQQLKTPQ
NSQSWREGGGGPNRQMGGARVDSPKVQCAESGSLLSPCVMRALEGVHYIADHLRAEDADF
SVKEDWKYVAMVIDRIFLWMFIIVCLLGTIGLFLPPWLAGMI
>Homo sapiens_CHRNA6(ENSP_276410)
MLTSKGQGFLHGGLCLWLCVFTPFFKGCVGCATEERLFHKLFSHYNQFIRPVENVSDPVT
VHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKLRWDPMEYDGIETLRVPADKIWKPDI
VLYNNAVGDFQVEGKTKALLKYNGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWT
YDKAEIDLLIIGSKVDMNDFWENSEWEIIDASGYKHDIKYNCCEEIYTDITYSFYIRRLP
MFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVV
PLVGEYLLFTMIFVTLSIVVTVFVLNIHYRTPTTHTMPRWVKTVFLKLLPQVLLMRWPLD
KTRGTGSDAVPRGLARRPAKGKLASHGEPRHLKECFHCHKSNELATSKRRLSHQPLQWVV
ENSEHSPEVEDVINSVQFIAENMKSHNETKEVEDDWKYVAMVVDRVFLWVFIIVCVFGTA
GLFLQPLLGNTGKS
>Pongo abelii_CHRNA6(ENSPPYP_20814)
MPTSKGQGFLHGGLCLWLCVFTPFFKGCAGCVTEERLFHKLFSHYNQFIRPVENVSDPVT
VHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKLRWDPTEYDGIETLRVPADKIWKPDI
VLYNNAVGDFQVEGKTKALLKYNGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWT
YDKAEIDLLIIGSKVDMNDFWENSEWEIIDASGYKHDIKYNCCEEIYTDITYSFYIRRLP
MFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVV
PLVGEYLLFTMIFVTLSIMVTVFVLNIHYRTPTMHTMPRWVKTVFLKLLPQVLLMRWPVD
KTRGTGSDAMPRGLARRPAKGKLASREEPRHLKECFHCHKSNELATSKRRLSHQPLQWMV
ENSEHSPEVEDVINSVQFIAENMKSHNETKQVEDDWKYVAMVVDRVFLWVFIIVCVFGTA
GLFLQPLLGNTGKS
>Mus musculus_CHRNA6(ENSMUSP_33882)
MLNSRDQGNLHSGLCLWLCGFLALFKGSTGCESEEQLFHRLFAHYNRFIRPVENVSDPVT
VHFELAITQLANVDEVNQIMETNLWLRHIWKDYRLRWDPTEYDGIETLRVPADNIWKPDI
VLYNNAVGDFQVEGKTKALLKYDGVITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWT
YDKAEIDLLIIGSKVDMNDFWENSEWEIVDASGYKHDIKYNCCEEIYTDITYSFYIRRLP
MFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVI
PLVGEYLLFTMIFVTLSIVVTVFVLNIHYRTPATHTMPKWVKTIFLQAFPSILMMRKPLD
KTKEAGGVKDPKSHTKRPAKVKFTHRGESKLLKECHHCQKSSDIAPGKRRSSQQPARWVA
ENSEHSSDVEDVIESVQFIAENMKSHNETNEVEDDWKYMAMVVDRVFLWVFIIVCVFGTV
GLFLQPLLGNTGKS
>Canis familiaris_CHRNA6(ENSCAFP_8128)
MLTSKGQGFLHFGLCLCSCIFIPCLKGSAGCASEERLFHKLFSHYNQFIRPVENVSDPVT
VHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKLRWNPMEYDGIETLRVPADRIWKPDI
VLYNNAVGDFQVEGKTKALLKYDGMIIWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWT
YDKAEIDLLIIGSKVDMNDFWENSEWEIVDASGYKHDIKYNCCEEIYTDITYSFYIRRLP
MFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVI
PLVGEYLLFTMIFVTLSIAVTVFVLNIHYRTPATHTMPKWVKTVFLQLLPQILMMRRPLD
KMRKTSSDKNSKGISSRPTKVNFDNYRETKLPKECCHCHKSSKLATSKRRLSHQSLQWMT
ENSEHWPDVEDVINSVQFIAENMKNQNETKEVEDDWKYVAMVVDRVFLWVFIFVCVFGTA
GLFLQPLLGNTGKS
>Myotis lucifugus_CHRNA6(ENSMLUP_4768)
MLTSKGQGCLHCGLCLWLYIFIPFFKDGAGCASEERLFHKLFSHYNQLIRPVENVSEPVT
VHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKLRWDPTEFDGIETIRVPADKIWKPDI
VLYNNAVGDFQVKGKTKALLKYDGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWT
YDKAEIDLLIIGSKVDMNDFWENSEWEIVDASGYKHDIKYNCCEEIYTDITYSFYIRRLP
MFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVI
PLVGEYLLFTMIFVTLSIAVTVFVLNIHYRTPTTHTMPDWVKMVFLQLLPQILMMKRPLD
KTRKTSSDKNPKSISGRPTKVKFDNRREPKLLKECCHCHKSHQLATSKRRLSHQPLQWMT
GNTEHSPEVEDVINSVQFIAENMKNQNETKEVEDDWKYVAMVVDRVFLWIFIIVCVFGTA
GLFLQPLLGNTGKS
>Homo sapiens_CHRNB3(ENSP_289957)
MLPDFMLVLIVLGIPSSATTGFNSIAENEDALLRHLFQGYQKWVRPVLHSNDTIKVYFGL
KISQLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFEN
ADGRFEGSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTM
VDLILINENVDRKDFFDNGEWEILNAKGMKGNRRDGVYSYPFITYSFVLRRLPLFYTLFL
IIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYL
LFIMIFVTLSIIVTVFVINVHHRSSSTYHPMAPWVKRLFLQKLPKLLCMKDHVDRYSSPE
KEESQPVVKGKVLEKKKQKQLSDGEKVLVAFLEKAADSIRYISRHVKKEHFISQVVQDWK
FVAQVLDRIFLWLFLIVSVTGSVLIFTPALKMWLHSYH
>Callithrix jacchus_CHRNB3(ENSCJAP_14325)
MLTDFMLVLIVLGIPSSATAGFSSIAENEDALLRHLFQGYQKWVRPVLHSNDTIKVYFGL
KISQLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFEN
ADGRFEGSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTM
VDLILINENVDRKEFFDNGEWEILNAKGMKGNRRDGVYSYPFITYSFVLRRLPLFYTLFL
IIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYL
LFIMIFVTLSIIVTVFVINVHHRSSSTYQPMAPWVKRLFLQKLPKLLCMKDHVDRYSIPE
KEESQPVVKSKVLEKKKHKQLSDGEKVLVAFLEKAADSIRYISSHVKKEHFISQVVQDWK
FVAQVLDRIFLWLFLIVSVTGSVLIFTPALKMWLHSYH
>Gallus gallus_CHRNB3(ENSGALP_24774)
MLCLMLCVLCWSRSDVAALGSVAENEDALLRHLFQGYQKWVRPVENSNDTIKVLFGLKIS
QLVDVDEKNQLMTTNVWLKQEWMDHKLSWNPEEYGGITAIRVPSESLWLPDIVLFENADG
RFEGSLMTKAIVKYNGVVTWMPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGSMVDL
ILVDENVDRKDFFDNGEWEILNAKGMKGNRKDGLYSYPFVTYSFVLRRLPLFYTLFLIIP
CLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFI
MIFVTLSIIVTVFVINVHHRSSATYHPMAPWVKRLFLQKLPRLLCMKGHVDRYSFSDTEE
KETTLKSKLPGKQKHKQAKDGEKVVIAFLEKAADSIRYISRHVKKEHFIRQVVQDWKFVA
QVLDRIFLWLFLVVSVTGSVLIFTPALQMWLNSTL
>Xenopus tropicalis_CHRNB3(ENSXETP_22596)
TMKMFIYACTNIIFIPSGFAKFHPLAEIEDALLRKLFAGYQKWVRPVLNPNSTIKVNFGL
KISQLVDVDEKKQLMTTNVWLRQEWMDMKLRWNPKDYGGITYIRVPSESLWLPDIVLFEN
ADGRFEGSLMTKAIIKYDGTVTWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGNM
VDLILLDENVDRKDFFDNGEWDILNATGLKGMRKDGLYSYPFITYSFVLRRLPLFYTLFL
IIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYL
LFIMIFVTLSIIVTVFVINVHHRSSATYHPMAPWVKRLFLEKLPKLLCMKGHVDRFSFFD
SESDVSSAKSKPSGKRKNIHASDGEKVLIAFLEKAADSIKYISTHVKKEHFIRQVVQDWK
FVAQVLDRIFLWLFLSVSITGSVLIFTPALQMWLNSHV
>Danio rerio_CHRNB3a(ENSDARP_69164)
MKLQISGILLVAAVAYATIEAPEEFVSLAEMEDTLLRNLFRGYQKWVRPVLHANDTITVR
FGLKISQLVDVDEKNQLMTTNVWLWEEWTDYKLRWNPEDYGGITSIRVPSETIWLPDIVL
YENADGRFEGSLMTKAIVRFNGTIMWTPPASYKSACTMDVTFFPFDRQNCSMKFGSWTYD
GTMVDLTLVDAYVDRKDFFDNGEWEILNATGQRGSRRDGIYSYPYLTYSFILKRLPLFYT
LFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIG
EYLLFIMIFVTFSIIVTVFVINVHHRSSATYHPMAPWVKSLFLQRLPRLLCMRGHTDRYQ
YPDIELRSPELKRGMKKGQQKSAGGGRAGVKEDENQAWIALLEKATHSVHYISRHIRKEH
FIREVVQDWKFVAQVLDRIFLWAFLTVSVLGTILIFTPALQMFFSTS
>Danio rerio_CHRNB3b(ENSDARP_50036)
MTLTVIGLFTLFTSIFATTPAREFVSLAEREDALLRDLFQGYQRWVRPILHANHTVKVRF
GLKISQLVDVDEKNQLMTTNVWLYEEWLDYKLRWNPENYGGITFIRVPSESIWLPDIVLY
ENADGRFEGSIMTKAIVRYNGLITWTPPASYKSACTMDVTFFPFDRQNCSMKFGSWTYDG
NMVELVLVNHQVDRSDFFDNGEWEILSATGHKGSRRDGHYSYPYITYSFILKRLPLFYTL
FLIIPCLGLSFLTVLVFYLPSDEGEKVSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGE
YLLFIMIFVTLSIIVTVFVINVHHRSSATYHPMSPWVRTLFLQRLPDLLCMRGNTDRYHY
PQMEPQSPDLKPRSKKGPPGPEGDGQALINMLEQATNSVRYISRHIKKEHFIREVVQDWK
FVAQVLDRIFLWAFLTVSVLGTILIFTPAVKMFLSTPPPPSP
>Takifugu rubripes_CHRNB3a(ENSTRUP_15529)
PPLLSVLLSVPIPLAPAEEDFVSLAELEDSLLRNLFKGYQKWVRPVQHANDTITVRFGLK
ISQLVDVDEKNQLMTTNVWLWQEWIDVKLKWNPDDYGGITAIRVPSETIWLPDIVLYENA
DGRFEGSLMTKAIVRWDGTITWTPPASYKSACNMDVTFFPFDRQNCSMKFGSWTYDGNMV
DLVLVDHYVDRKDFFDNGEWEILNATGVKGSRRDEVYWYPFVTYSFILKRLPLFYTLFLI
IPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLL
FIMIFVTFSIIVTVFVINVHHRSSATYHPMAPWVKSLFLQRLPRLLCMRGHTDRYNFPDN
EMRSPEPKPRRAIGRRGVQGKEDENQAWLAMLEKATNSVRYISQHIRKEHFIREVVQDWK
FVAQVLDRIFLWAFLTVSILGTVLIFTPALKMYLHKMFH
>Takifugu rubripes_CHRNB3b(ENSTRUP_4037)
HLPDQLVCAKTSLSAPAQSEFVSLAEMEDALLRNLFQGYQRWVRPIQHANDTIKVRFGLK
ISQLVDVDEKNQLMTTNVWLCQEWIDFKLRWNPDKYGGITSIRVPSENLWLPDIVLYENA
DGRFEGSLMTKAIVRYNGAITWTPPASYKSACTMDVTFFPFDRQNCTMKFGSWTYDGTMV
DLILIDKQVDRKDFFDNGEWEILSATGAKGNRKDGLYSYPFITYSFILKRLPLFYTLFLI
IPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLL
FIMIFVTLSIIVTVFVINVHHRSSATYHPMSPWVRTLFLQKLPSLLCMRGHTDRYHYPEL
GPESPEPKPRSGGRRGGQRISSGGTYGQASSEGKDDEDWATMLDKAIFSVRYISRHIRKE
HFIREVVQDWKFVAQVLDRIFLWAFLTVSVLGTILIFTPALQKFMQVLP
>Tetraodon nigroviridis_CHRNB3a(ENSTNIP_16128)
LLVASVCFFPVFHMFAPAQSEFVSLAEMEDALLRNLFQGYQRWVRPIQHANDTIKVRFGL
KISQLVDVDEKNQLMTTNVWLCQEWIDYKLRWNPDKYGGITSIRVPSENLWLPDIVLYEN
ADGRFEGSLMTKAIVRYNGAITWTPPASYKSACTMDVTFFPFDRQNCTMKFGSWTYDGTM
VDLILIDKQVDRKDFFDNGEWEILSATGAKGNRKDGLYSYPFITYSFILKRLPLFYTLFL
IIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYL
LFIMIFVTLSIIVTVFVINVHHRSSATYHPMSPWVRTLFLQKLPRLLCMRGHTDRYHYPE
LGPESPEPRVRAGGRRGGQRVGSGSHGQTPPEGKDDEEWASMLDKAIYSVRYISRHIRKE
HFIREVVQDWKFVAQVLDRIFLWAFLTVSVLGTILIFTPALQKFMKVLPQSSS
>Tetraodon nigroviridis_CHRNB3b(ENSTNIP_14999)
QEDFVSLAELEDSLLRNLFRGYQKWVRPVQHANDTITVRFGLKISQLVDVDEKNQLMTTN
VWLWQEWVDVKLKWNPDDYGGITAIRVPSETIWLPDIVLYENADGRFEGSLMTKAIVRWD
GTITWTPPASYKSACTMDVTFFPFDRQNCSMKFGSWTYDGNMVDLVLVDHYVDRKDFFDN
GEWEILNATGVKGSRRDGIYWYPFVTYSFILKRLPLFYTLFLIIPCLGLSFLTVLVFYLP
SDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTFSIIVTVFVI
NVHHRSSATYHPMAPWVKSLFLQRLPRLLCMRGHTDRYHFPDMEMHSPELKPRRAVGRRG
VQGQQKGPLAGKEDENQAWLAMLEKATNSVRYISQHIRKEHFIREVVQDWKFVAQVLDRI
FLWAFLTVSILGTVLIFTPALQMYLSTP
>Gasterosteus aculeatus_CHRNB3a(ENSGACP_24319)
QDDVVSLAEMEDSLLRNLFRGYQKWVRPVLHSNDTITVCFGLKISQLVDVDEKNQLMTTN
VWLWQEWVDLKLKWNPDDYGGITSIRVPSETIWLPDIVLYENADGRFEGSLMTKAIVRWD
GTITWTPPASYKSACTMDVTFFPFDRQNCSMKFGSWTYDGNMVDLVLVDHYVDRKDFFDN
GEWEILNATGQRGSRRDEVYWYPFVTYSFILKRLPLFYTLFLIIPCLGLSFLTVLVFYLP
SDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLHHRSSSTYHPMAPWVKSL
FLQRLPRLLCMRGHTDRYHFEDMEMHSPEVKTRRGVGRRGAPGQRGPVSGKEEENRAWLA
MLEKATSSVRYISRHIKKEHFIREVVQDWKFVAQVLDRILLWAFLTVSILGTVLIFTPAL
QMYFSTP
>Gasterosteus aculeatus_CHRNB3b(ENSGACP_23418)
MKWTVLFLLLVCPLSLAEIHAPSEFVSLAEMEDALMRNLFQGYQRWVRPIQHANDTVRVR
FGLKISQLVDVDEKNQLMTTNVWLWQEWIDYKLRWNPDKYGGITSIRVPSEIIWLPDIVL
YENADGRFEGSLMTKAIVKFNGVITWTPPASYKSACTMDVTFFPFDRQNCTMKFGSWTYD
GHMVDLVLIDNQVDRRDFFDNGEWEILSATGARGTRKDDMYTYPFLTYSFILKRLPLFYT
LFLIFPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIG
EYLLRSSATYHPMSPWVRNLFLQKLPRFLCMRGHTDLYHYPELAPESPEMKPRSGGRKGG
QRANSGARGQTASEGKEDEAWATMLDKAVYSVRYISRHIRKEHFIREVVQDWKFVAQVLD
RIFLWAFLTVSILGTVLIFTPALYSFFKIP
>Oryzias latipes_CHRNB3a(ENSORLP_17917)
FPLLPVQENVLSLAELEDSLLRNLFKGYQKWVRPVQHANDTITVRFGLKISQLVDVDEKN
QLMTTNVWLWQEWIDVKLKWNPDDYGGITSIRVPSETIWLPDIVLYENADGRFEGSLMTK
AIVRWDGTITWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGNMVDLVLVDHYVDR
KDFFDNGEWEILNATGQRGSRRDEMYWYPFLTYSFILKRLPLFYTLFLIIPCLGLSFLTV
LVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTFSII
VTVFVINVHHRSSATYHPMAPWVKSLFLQKLPRLLCMRGHTDRYHFPDIEMRSPELKTRR
GAGRRAVPGGMEDDSQAWLAMLEKATNSVHYISRHIRKEHFIREVVQDWKFVAQVLDRIF
LWAFLTVSILGTVLIFTPALQSYLSTP
>Oryzias latipes_CHRNB3b(ENSORLP_4018)
LTVFLLLLLSACPQLFAAITAPKRFVSLAEMEDDLLKNLFQGYQRWVRPIQRPNDTVRVR
FGLKISQLVDVDEKNQLMTTNVWLRQEWIDYKLRWNPDKYGGITSIRVPSENIWLPDIVL
YENADGKFEGSLMTKAIVKFNGAVTWMPPASYKSACTMDVTFFPFDRQNCSMKFGSWTYD
GNMVDLVLMDSQVDRKDFFDNGEWEILSATGAKGNRKDGLYFYPFITCSFILKRLPLFYT
LFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIG
EYLLFIMIFVTLSIIVTVFVINVHHRSSATYHPMSPWVRSLFLQKLPRLLCMRGHADRYH
YPELAPESPALKSRSGGRRGIQRMSSGGQQSTYDGKEEEAYSTMLEKAIYSVRYISRHIR
KDHFIREVVQDWKFVAQVLDRIFLWIFLSVSVLGTILIFTPALQMFMKIPPPAPSE
>Homo sapiens_CHRNA4(ENSP_359285)
MELGGPGAPRLLPPLLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISD
VVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWR
PDIVLYNNADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFG
SWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVDAVGTYNTRKYECCAEIYPDITYAFVIR
RLPLFYTINLIIPCLLISCLTVLVFYLPSECGEKITLCISVLLSLTVFLLLITEIIPSTS
LVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPRTHTMPTWVRRVFLDIVPRLLLMKR
PSVVKDNCRRLIESMHKMASAPRFWPEPEGEPPATSGTQSLHPPSPSFCVPLDVPAEPGP
SCKSPSDQLPPQQPLEAEKASPHPSPGPCRPPHGTQAPGLAKARSLSVQHMSSPGEAVEG
GVRCRSRSIQYCVPRDDAAPEADGQAAGALASRNTHSAELPPPDQPSPCKCTCKKEPSSV
SPSATVKTRSTKAPPPHLPLSPALTRAVEGVQYIADHLKAEDTDFSVKEDWKYVAMVIDR
IFLWMFIIVCLLGTVGLFLPPWLAGMI
>Mus musculus_CHRNA4(ENSMUSP_66338)
MEIGGSGAPPPLLLLPLLLLLGTGLLPASSHIETRAHAEERLLKRLFSGYNKWSRPVANI
SDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPGDYENVTSIRIPSELI
WRPDIVLYNNADGDFAVTHLTKAHLFYDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK
FGSWTYDKAKIDLVSMHSRVDQLDFWESGEWVIVDAVGTYNTRKYECCAEIYPDITYAFI
IRRLPLFYTINLIIPCLLISCLTVLVFYLPSECGEKVTLCISVLLSLTVFLLLITEIIPS
TSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPRTHTMPAWVRRVFLDIVPRLLFM
KRPSVVKDNCRRLIESMHKMANAPRFWPEPESEPGILGDICNQGLSPAPTFCNRMDTAVE
TQPTCRSPSHKVPDLKTSEVEKASPCPSPGSCHPPNSSGAPVLIKARSLSVQHVPSSQEA
AEGSIRCRSRSIQYCVSQDGAASLTESKPTGSPASLKTRPSQLPVSDQTSPCKCTCKEPS
PVSPITVLKAGGTKAPPQHLPLSPALTRAVEGVQYIADHLKAEDTDFSVKEDWKYVAMVI
DRIFLWMFIIVCLLGTVGLFLPPWLAGMI
>Monodelphis domestica_CHRNA4(ENSMODP_21042)
MRLQGPQGSALLLLLLRGLLILGVLLPASGHVETRAHAEERLLKKLFSGYNKWSRPVANI
SDVVLVRFGLSIAQLIDVDEKNQMMTTNMWVKQEWQDYKLRWDPMDYENVTSIRIPSELI
WRPDIVLYNNADGDFAVTHLTKAHLFYDGRIKWTPPAIYKSSCSIDVTFFPFDQQNCTMK
FGSWTYDKAKIDLVSMHSHVDQLDYWESGEWVIISAVGNYNIKKYECCTETYSDITYSFI
IRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPS
TSLVIPLIGEYLLFTMIFVTLSIIITVFVLNVHHRSPRTHTMPAWVRRVFLDIIPRLLFM
KRPGVVKDNCRKLVESMHKLAGGPRFWPQPEPNFVTSPSTSPQTPERSPSASFCVHLEDP
VKPQAVCKSPSGQYTVLQRPEPGKGSPCSPPTPHPPLNNSHPSGFSKVRSLSVQQMYSSN
KVEEGSIRCRSRSIQYCSLQEDSSQANNGQSTSSPASLRSQKDEVQPQEKPSPCKCKCKK
VKATPVPDPVTKPRSTKEQHALPMSPALKLAVEGVQYIADHLKAEDTDFSVKEDWKYVAM
VIDRIFLWMFVIVCLLGTVGLFLPPWLAGMI
>Danio rerio_CHRNA4(ENSDARP_22694)
MRAAWRVFFLLCVHLQLAYVFSMSPAHAHAEERLLQSLFINYNKLSRPVANISDVVLVHF
GLSIAQLIDVDEKNQMMTTNVWVKQEWNDYKLRWNPEEYENVTSIRIPSEIIWRPDIVLY
NNADGDFAVTHLTKAQVFYNGRIKWKPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDR
AKIDLISMASDVDQMDYWESGEWVIINAVGTYNIKKYECCTEIYPDITYSFIIRRLPLFY
TINLIIPCLLISCLTVLVFYLPSECAEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLI
GEYLLFTMIFVTLSIIITVFVLNVHHRSSRTHSMPHWVRQLFLHLVPRYLFMKRPPASGK
RNCGKLIEMMHKQANSQSMFLRNNILDISPQSPIPHLGPTSAAQQDQVQQDSTSPKPLFF
CSSPSSQYSILQEENSQTPQTPVLSYTCAYTNSIFASSTTSFPDTLLGTLLHTIPQDGAK
STECDFQGHSAESVFMEAKESVLGAGSCQHCLTSEGTSLQKLDLDEAGRCTRHNMPSAQI
FSPSSDGSTDLNAAEPVSNLSQSLLKALEGVQYIADHLRAEDSDFSVREDWKYVAMVIDR
IFLWMFVLVCILGTVGLFLPPWLAGMI
>Takifugu rubripes_CHRNA4(ENSTRUP_25718)
TEWISSGLDPPALPHHLHFIWITSSSLAGFSQVAPRAHAEERLLQDLFAHYNKLSRPVEN
TTDTVLVHFGLSIAQLIDVDEKNQMMTTNVWVKQEWNDYKLRWNPEEYENVTSIRIPSEI
IWRPDIVLYNNADGDFAVTHLTKAQLFYDGRIKWMPPAIYKSSCSIDVTFFPFDQQSCKM
KFGSWTYDRAKIDLISMASDVDQMDYWESGEWVIVNAVGKYNTKKYECCTEIYSDITYYF
IIRRLPLFYTINLIIPCLLISCLTVLVFYLPSQCGEKITLCISVLLSLTVFLLLITEIIP
STSLVIPLIGEYLLFTMVFVTLSIIITVFVLNVHHRSPQTHGMPHWVRRVFLDFVPKVLF
MKRPPGTAKQHCKKLIEMMHRPATVSGPSPSPPSSPLANCNKDNQSLNANTFCQSISGRY
SLLSEKQLLHGHKSAASSSSQLSLPPTLPLGLLHKRTNKESNTMASIGRSLSVEHMFDGQ
KEAPCRGRYRRRSRSFQYCCLHDEGAGLTRATWGQKKHPSADHLVEIIMAESTKDTSSLQ
DFEVSTISPAMQRAIEGVQYIADHLRAEDADFSVKEDWKYVAMVIDRIFLWMFVLVCILG
SVGLFLPPWLAGMI
>Tetraodon nigroviridis_CHRNA4(ENSTNIP_6787)
IQVAPRARRRRLLRDLFAHYNRLSRPVENTTDTVLVHFGLSIAQLIDVDEKNQMMTTNVW
VKQEWNDYKLRWNPEEYENVTSIRIPSEIIWRPDIVLYNNADGDFAVTHLTKAQLFYDGR
IKWMPPAIYKSSCSIDVTFFPFDQQSCKMKFGSWTYDRAKIDLVSMASDVDQMDYWESGE
WVIVNAVGKYNIKKYECCTEIYSDITYYFIIRRLPLFYTINLIIPCLLISCLTVLVFYLP
SQCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMVFVTLSIIITVFVL
NVHHRSPQTHGMPHWVRRVFLDFVPKVLFMKRPPGTAKQHCKKLIEMMHRPATVSEVENS
SSFWTGLETELRQMGQVQKTIPKALTDSPSIRISSPSPPSSPLVNCNKGNQSLNANTFCQ
SISGQYSLLSEKKLLHGHKTAAFSSSQLSLPPTLPLGRLHNHTDEESNTIALNGRSLSVE
HMFDDRKEASRPGGYRRRSRSFQYCCLHDEGVGLTRTTGEMKKQPSADHLGETIMAESTK
DTSSLQNIELSTISPAMQRAIEGVQYIADHLRAEDSDFSVKEDWKYVAMVIDRIFLWMFI
LVCILGSVGLFLPPWLAGMI
>Gasterosteus aculeatus_CHRNA4(ENSGACP_6142)
LPPLLSYLVANLCLSRTHVRPRAHAEERLLQDLFARYNKLSRPVENTSDTVLVHFGLSIA
QLIDVDEKNQMMTTNVWVKQEWSDYKLRWKPEDYENVSSIRIPSEIIWRPDIVLYNNADG
DFAVTHLTKAHLFHDGRIKWMPPAIYKSSCSIDVTFFPFDQQSCKMKFGSWTYDRAKIDL
ISMASDVDQMDYWESGEWVIINAVGKYNTKKYECCAEIYSDITYYFIIRRLPLFYTINLI
IPCLLISCLTVLVFYLPSQCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLL
FTMVFVTLSIVITVFVLNVHHRSPQTHSMPHWVRRVFLDMVPRVLFMKRPPGTAKQHCKK
LIEMMHRPTAISATGNSLAYWTGLETGLRQMCQAENALPKTPCDSPSIHVCSPAPPSSPP
EDCEEDDRLLKANLSLPPALPLGPLRSFSQEEPNAMAPNGRSLSAEQMFDQQGDLSQRAG
HRCRSRSFQYCCLHGEGPGLMAVAGWVKKQAPTNHPAGRVTGESTKDASTQQDIVIPTIS
PAVQRAIEGVQYVADHLRAEDADFSVKEDWKYVAMVIDRIFLWMFVLVCILGSVGLFLPP
WLAGMI
>Oryzias latipes_CHRNA4(ENSORLP_1058)
SSQIEPRAHAEERLLQNLFARYNKLSRPVQNTSDTVLVHFGLSIAQLIDVDEKNQMMTTN
VWLKQEWNDYKLRWNPEDYENVTSIRIPSEIIWRPDIVLYNNHSADGDFAVTHLTKAHLF
YDGQIKWMPPAIYKSSCSIDVTFFPFDQQSCKMKFGSWTYDRAKIDLISMASDVDQMDYW
ESGEWVIVNAVGKYNTKKYECCAEIYADITYYFIIRRLPLFYTINLIIPCLLISCLTVLV
FYLPSQCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMVFVTLSIIIT
IFVLNVHHRSPQTHGMPHWVRRVFLDLVPRVLFMKRPPGTAKQHCKRLIEMMHCPTTISA
TGNSQSFWTGLDSELRQMTQVHNSLPKVDSPRILVCSPSPSSSPVDDCSDEDHPLKADIF
CQTPSGQYSPLLEHQALCRHISTTHSAPQLSMPLGPFPCLSREHPSPLARNGRSLSVEQM
CGKQGQPPQRSAHRCRSQSFQYCCLHNDGAAGFTGQTNKTPEQLTETLAAEFAKDASTQL
DNMAPIVSPAMQRAIEGVQYIADHLRAGDADFSVKEDWKYVAMVIDRIFLWMFVLVCILG
SVGLFLPPWLAGMI
>Homo sapiens_CHRNA3(ENSP_315602)
MGSGPLSLPLALSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDPV
IIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPD
IVLYNNAVGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSW
SYDKAKIDLVLIGSSMNLKDYWESGEWAIIKAPGYKHDIKYNCCEEIYPDITYSLYIRRL
PLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLV
IPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPTTHTMPSWVKTVFLNLLPRVMFMTRPT
SNEGNAQKPRPLYGAELSNLNCFSRAESKGCKEGYPCQDGMCGYCHHRRIKISNFSANLT
RSSSSESVDAVLSLSALSPEIKEAIQSVKYIAENMKAQNEAKEIQDDWKYVAMVIDRIFL
WVFTLVCILGTAGLFLQPLMAREDA
>Oryctolagus cuniculus_CHRNA3(ENSOCUP_4351)
MGAPPPPPPSPVLLLLLLLLPPVVSASEAEHRLFERLFEDYNEIIRPVANVSDPVIIQFE
VSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYNGAEFMRVPAQKIWKPDIVLYN
NAVGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKA
KIDLVLIGSSMNLRDYWESGEWAIIKAPGYKHDIKYNCCEEIYTDITYSLYIRRLPLFYT
INLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIG
EYLLFTMIFVTLSIVITVFVLNVHYRTPTTHTMPAWVKTVFLNFLPRVMFMTRPASDGDS
AQMPQLLAGAELSNLGCFGRTEPKACKEGCPCQDGACGYRHHRRVKMSNFGANLTRSSSL
ESVDAVLSLSALSPEIREAIRSVQYIAENMKAQNEAKEIQDDWKYVAMVIDRIFLWVFIL
VCILGTAGLFLQPLMARDDA
>Taeniopygia guttata_CHRNA3(ENSTGUP_3582)
GCGGSEAEHRLYAALFKSYNQFVRPVKNVSDPVIIQFEVSMSQLVKVDEVNQIMETNLWL
KHIWNDYKLRWNPADYGGAEFIRVPSGQIWKPDIVLYNNAVGDFQVDDKTKALLKYTGDV
TWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSTMNLKDYWESGEW
AIIKAPGYKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINMIIPCLLISFLTVLVFYLPS
DCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLN
VHYRTPKTHTMPVWVKTIFLNLLPRIMFMTRPASDEENNQKPKPLFTSEFSNLNCINGSE
TKSCKDGFACQDMACSCCQYQRTNSESVDPMLSFSVLSPEMRDAIESVKYIAENMKMQNE
AKEIQDDWKYVAMVIDRIFLWVFILVCILGTAGLFLQPLM
>Pelodiscus sinensis_CHRNA3(ENSPSIP_19032)
QTSAPLSLPSTAFSKEVSLLILPATLSVSNCSEAEHRLFASLFANYSQFIRPVENVSDPA
IIQFEVSMSQLVKVDEVNQIMETNLWLKHIWNDYKLKWNPEEYGGAEFIRVPSDSIWKPD
IVLYNNAVGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSW
SYDKAKIDLVLIGSTMNLKDYWESGEWAIIKAPGYKHDIKYNCCEELYPDITYSLYIRRL
PLFYTINMIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLV
IPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPKTHTMPEWVKTIFLNLLPKIMFMTRPA
SDEETTQKLKPLYSVELSDLNCFSSSETKCCKEGFICQDTACSCCRYQRIKFSDFSGNLT
RSSSYESVDALLSLSVLSPEIRDAIESVKYIAENMKMQNEAKEIQDDWKYVAMVIDRIFL
WVFILVCILGTAGLFLQPLMTRDEI
>Danio rerio_CHRNA3(ENSDARP_132461)
MQLIHFIIASTIQLCVSVSGVCCSEAEHRLFSVIFSSYNQYIRPVENVSDPVVVQFEVSM
SQLVKVDEVNQIMETNLWLRHIWNDYKLRWDPKDFGGVEFIRVPSNKIWKPDIVLYNNAV
GDFQVDDKTKALLRFNGDVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWTYDKAKID
LVLIGSTINLKDFWESGEWTIIDAPGYKHDIKYNCCEEIYTDITYSLYIRRLPLFYTINM
IIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYL
LFTMIFVTLSIVITVFVLNVHYRTPKTHTMPCWVRRVFLSLLPRVMFMTRPEKDQEVPAK
HKQTSVCRGPQLLLCPTELNEASRTAFLCREHHCWKKHISNMTSEGAEDGGSPCSSSESL
DGFLCMSAVSPQVREAIESVKYIAENMRLQNEAKEVQDDWKYVAMVIDRIFLWVFVLVCI
LGTAGLFLQPLLLGEDM
>Takifugu rubripes_CHRNA3(ENSTRUP_9649)
LLFLLPGGCCSEAEHKLFSVIFSNYNQYIRPVENVTDPVIVQFEVSMSQLVKVDEVNQIM
ETNLWLRHIWNDYKLRWPKEYGGVEYIRVPSSRIWKPDIVLYNNAVGDFQVDDKTKALLR
YNGDVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWTYDKAKIDLVLIGSTMNLKDFW
ETGDWLIIDAPGYKHDIKYNCCEEIYTDITYSLYIRRLPLFYTINLIIPCLLISFLTVLV
FYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVIT
VFVLNVHYRTPKTHTMPCWVRAVFLELLPRVMFMTRPERHAFQVLRRPLSNTELSNLNNL
SGDPSKGSTSLCCEGRCNCCWYQRSRGSVAKVSGGSQRSSSESLNGGLMPLLPLSPEVRE
AIESVRYIAENMRLQNEAKEVQDDWKYVAMVIDRIFLWVFVLVCILGTAGLFLQPLLLAE
DI
>Tetraodon nigroviridis_CHRNA3(ENSTNIP_2840)
LLFRLPGGSCSEAEHKLFSVIFSNYNQYIRPVENVTDPVIVQFEVSMSQLVKVDEVNQIM
ETNLWLRHIWNDYKLRWNPKEYGGVEYIRVPSSRIWKPDIVLYNNAVGDFQVDDKTKALL
RYNGDVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWTYDKAKIDLVLIGSTMNLKDF
WETGDWLIIDAPGYKHDIKYNCCEEIYTDITYSLYIRRLPLFYTINLIIPCLLISFLTVL
VFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVI
TVFVLNVHYRTPKTHTMPRWVRAVFLELLPRVMFMIRPEREPEQGRGAGNAQDMHPRSCS
VHSSELSNLNNLSGDLTKGSTSLCCEGRCNCCWYQRSKVSGGSQCSSSDSLNGGLMPQLP
LSPEVREAIESVRYIAENMRLQNEAKEVQDDWKYVAMVIDRIFLWVFVLVCILGTAGLFL
QPLLLAEDI
>Gasterosteus aculeatus_CHRNA3(ENSGACP_21875)
AEHKLFSVIFSSYNQYIRPVENVTDPVVVQFEVSMSQLVKVDEVNQIMETNLWLRHIWND
YKLRWNPKDFGGVDFIRVPSNRIWKPDIVLYNNAVGDFQVDDKTKALLRFNGDVTWIPPA
IFKSSCKIDVTYFPFDYQNCTMKFGSWTYDKAKIDLVLIGSTINLKDFWESGEWTIIDAP
GYKHDIKYNCCEEIYTDITYSLYIRRLPLFYTINMIIPCLLISFLTVLVFYLPSDCGEKI
TLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTP
KTHTMPCWVRTVFLGLLPRVMFMTRPETDAERVLAAAGDVQTTHLRPCAIHPSGALQKQH
KPQAPPPPSVVSSLTNRQRLFNNTELSDLNNLSGDPAKGAGSALLCCKGHCNCCWRQRSS
KLPADSGGGSGGLGSMGALSGGSAVGGGSHCSSSESVAGGTMSMLPLSPEVQEAIESVKY
IAENMRLQNEAKEVQDDWKYVAMVIDRIFLWVFVLVCILGTAGLFLQPLLLWDDI
>Homo sapiens_CHRNB4(ENSP_261751)
MRRAPSLVLFFLVALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQL
SLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNN
ADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTE
IDMVLMTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVDVTYDFIIKRKPLFYTINLI
IPCVLTTLLAILVFYLPSDCGEKMTLCISVLLALTFFLLLISKIVPPTSLDVPLIGKYLM
FTMVLVTFSIVTSVCVLNVHHRSPSTHTMAPWVKRCFLHKLPTFLFMKRPGPDSSPARAF
PPSKSCVTKPEATATSTSPSNFYGNSMYFVNPASAASKSPAGSTPVAIPRDFWLRSSGRF
RQDVQEALEGVSFIAQHMKNDDEDQSVVEDWKYVAMVVDRLFLWVFMFVCVLGTVGLFLP
PLFQTHAASEGPYAAQRD
>Danio rerio_CHRNB4(ENSDARP_139554)
XGVCADSEERLMNWLLGKHRYNKLIRPALNRTERVTVLLQVSLAQLISVNEREQIMTTNV
WLTQNWNDYRLSWDPAEYEGIDKLRIPSRHIWLPDIVLYNNADGTYEVTVFTNAIVLFNG
SIAWLPPAIYKSACKIEVKHFPFDQQNCTLKFRSWTYDHTEIDLLLKSDAASMDDFTPSG
EWDILALPGRRTVSPLDATYVDLTYDFIIKRKPLFYTINLIIPCVLITSLAILVFYLPSD
CGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLIGKYLMFTMVLVTFSIITSVCVLNV
HHRSPSTHSMPAWVKIVFLVRLPALLFMQRPRGHSARQRLRQNRRLLGLADTPGRSVMCS
SASALLAASSASALSSPGLLYNKGHFGSRRAEGLNNGHGSAQDLKGNRLYCEWGSEIQEA
VDGVRYVADHMMGNDDDQSVIEDWKYVAMVVDRLFLWIFVIVCVVGTLGLFLQPLFQNQT
LAIQQPNTEPARRDGM
>Takifugu rubripes_CHRNB4(ENSTRUP_9641)
LWGRLMTVLSLNSLIYHGVPSGCRCADSEERLMNWLLGKNRYNPLIRPASNRTERVPVKL
QVSLAQLISVNEREQIMTTNLWLMQHWVDYRLSWDPAKYEGINKLRIPSRLIWLPDIVLY
NNADGTYEVTVFTNAIVLFNGSINWLPPAIYKSACKIEVKHFPFDQQNCTLKFRSWTYDR
TEIDLVLKTDAASMDDFTPSGEWDILALPGRRTVNPLDPTYVDLTYDFIIKRKPLFYTIN
LIIPCILITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLIGKY
LMFTMVLVTFSIITSVCVLNVHHRSPSTHTMPSWVKLIFLVKLPSLLFIRRPQNNSARQR
LQSQRCQRAKRDILGLGCQPKSSITMLSSALLSPGSVFSTPGQKNVAPSLSLNITQNLQQ
SSGADWAADVQEALSGVRFVAEHMMEDDDDQSVIEDWKYVAMVVDRMFLWIFVIVCVVGT
LGLFLQPVFQNPITPIQQPSSDM
>Gasterosteus aculeatus_CHRNB4(ENSGACP_21862)
FGCEYTTCAFKLWNINVSPGSRCAESEERLMNWLLGKDRYNLLIRPAVNRTERVPVKLQV
SLAQLISVNEREQIMTTNVWLTQHWVDYRLSWDPAKYEGIDKLRIPSRHIWLPDIVLYNN
ADGTYEVTVFTNAIVIFNGSINWLPPAIYKSACKIEVKHFPFDQQNCTLKFRSWTYDHTE
IDLILKSEVASMDDFTPSGEWDILALPGRRTVNPLDPTYVDLTYDFIIKRKPLFYTINLI
IPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLIGKYLM
FTMVLVTFSIITSVCVLNVHHRSPSTHTMPSWVKLIFLVKLPALLFMRRPQNNSASQRLR
RQRCLRARKSIGSSGYPDAAKTGFILSPSALKGDLRSTDYIPSGQDLKQSTSSDWAADVQ
EAVNGVRFVAEHMMGDDDDQSVIEDWKYVAMVVDRMFLWIFVIVCVVGTLGLFLQPVFQT
QIVPNQQ
>Oryzias latipes_CHRNB4(ENSORLP_16438)
CKSADSEERLMNMLLGKHRYNPLIRPAINRTERVEVKLQVSLAQLISVNEREQIMTTNVW
ITQHWVDYRLSWDPAKYEGIQKLRIPSRHVWLPDIVLYNNADGIYEVTVFTNVIVLFNGS
VNWLPPAIYKSACKIEVKHFPFDLQNCTLKFRSWTYDHTEIDLILKSEAASMDDFTPSGE
WDIIALPGRRTVNPTDPTYVDLTYDFIIKRKPLFYTINLIIPCILITSLAILVFYLPSDC
GEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLIGKYLMFTMVLVTFSIITSVCVLNVH
HRSPSTHTMPSWVKLIFLKKLPALLFMKRPNNFSGCQRLRQQRCLRARRSILGLDYPNAS
KACFTLSSSALLPSDSAFSTPRHKNLAPTMGYGLSRRKGDLSSSDYPHISLTPTQDYQQK
CKSDWTADVKEAVKGVRFVAEHMMADDDDQSVIEDWKYVAMVVDRMFLWIFVIVCVVGTL
GLFLQPLFQSQMITSQQPSSDKPRI
>Homo sapiens_CHRNB1(ENSP_304290)
MTPGALLMLLGALGAPLAPGVRGSEAEGRLREKLFSGYDSSVRPAREVGDRVRVSVGLIL
AQLISLNEKDEEMSTKVYLDLEWTDYRLSWDPAEHDGIDSLRITAESVWLPDVVLLNNND
GNFDVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVFSSYSYDSSEVS
LQTGLGPDGQGHQEIHIHEGTFIENGQWEIIHKPSRLIQPPGDPRGGREGQRQEVIFYLI
IRRKPLFYLVNVIAPCILITLLAIFVFYLPPDAGEKMGLSIFALLTLTVFLLLLADKVPE
TSLSVPIIIKYLMFTMVLVTFSVILSVVVLNLHHRSPHTHQMPLWVRQIFIHKLPLYLRL
KRPKPERDLMPEPPHCSSPGSGWGRGTDEYFIRKPPSDFLFPKPNRFQPELSAPDLRRFI
DGPNRAVALLPELREVVSSISYIARQLQEQEDHDALKEDWQFVAMVVDRLFLWTFIIFTS
VGTLVIFLDATYHLPPPDPFP
>Gorilla gorilla_CHRNB1(ENSGGOP_22459)
MTPGALLMLLGALGAPLAPGVRGSEAEGRLREKLFSGYDSSVRPAREVGDRVRVSVGLIL
AQLISLNEKDEEMSTKVYLDLEWTDYRLSWDPAEHDGIDLLRITAESVWLPDVVLLNNND
GNFDVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVFSSYSYDSSEVS
LQTRLGPDGQGHQEIHIHEGTFIATSSLTSYLPGQYIIVIEKSVFEWPGNMITDYAIELS
FSSALQGEKMGLSIFALLTLTVFLLLLADKVPETSLSVPIIIKYLMFTMVLVTFSVILSV
VVLNLHHRSPHTHQMPLWVRQIFIHKLPLYLRLKRPKPERDLMPEPPHCSSPGSDWGRGT
DEYFIRKPPSDFLFPKPNRFQPELPAPDLRRFIDGPNRAVALLPELREVVSSISYIARQL
QEQEDHDALKEDWQFVAMVVDRLFLWTFIIFTSVGTLVIFLDATYHLPPPDPFP
>Mus musculus_CHRNB1(ENSMUSP_47270)
MALGALLLLLGVLGTPLAPGARGSEAEGQLIKKLFSNYDSSVRPAREVGDRVGVSIGLTL
AQLISLNEKDEEMSTKVYLDLEWTDYRLSWDPAEHDGIDSLRITAESVWLPDVVLLNNND
GNFDVALDINVVVSFEGSVRWQPPGLYRSSCSIQVTYFPFDWQNCTMVFSSYSYDSSEVS
LKTGLDPEGEERQEVYIHEGTFIENGQWEIIHKPSRLIQLPGDQRGGKEGHHEEVIFYLI
IRRKPLFYLVNVIAPCILITLLAIFVFYLPPDAGEKMGLSIFALLTLTVFLLLLADKVPE
TSLAVPIIIKYLMFTMVLVTFSVILSVVVLNLHHRSPHTHQMPFWVRQIFIHKLPPYLGL
KRPKPERDQLPEPHHSLSPRSGWGRGTDEYFIRKPPSDFLFPKLNRFQPESSAPDLRRFI
DGPTRAVGLPQELREVISSISYMARQLQEQEDHDALKEDWQFVAMVVDRLFLWTFIVFTS
VGTLVIFLDATYHLPPPEPFP
>Danio rerio_CHRNB1(ENSDARP_92302)
MKAQDWIIVTCCLCGLGAMTGATEMEDKLMKKLFSAYNSKVRPARNPEERVVVRIGMILS
SFVSLNMKDEEMNTIVMMNLEWNDYRLSWNPKDYGGVDVLRISSGKVWLPDIVLINNNDG
VFGVALQVHVQAYSNGRVTWTPPALYKSSCGVKVTYFPFDWQNCTMVFRSYTYDSSEVDL
QHALDKRGKEIKEIILDTGFSESGEWHIRHKVSRKNVREDLYEDITFYLIIERKPMFYVV
NIVLPCILITIIAIFNFYLPPDAGEKMGLSINVLLTLTVFLLLLANKIPETSLGVPIIVN
YLMITMILVTFSVILSVVVLNLHHRSPNTHQMPLWVRKIFIHMLPPYLGMLRPKVETPLF
LEKPAKKENIQAISRVADEYFIRKPSNMNFLFPKPHRYQPDGQCTDLRKFIDGPSHYLTL
PPELKTAVEAITYIAEQLQAEKDYEALKEDWQYVAMVADRLFLWIFVIFTTLGTLGIFTD
ASFNATPTDPFP
>Takifugu rubripes_CHRNB1a(ENSTRUP_10238)
STMKYLLLLPLSCCLCSLIPLGGASEVEKTLMKTLFSNYTLKVRPAISPEQRVVVRVGMI
LSSFVGLNMKNEEMSTIVVMNLEWTDYRLSWSPKQYGGIEVLRIPSGKVWLPDIVLINNN
DGVFHVALHVHVQVYSNGRVTWTPPALYCSSCGVKVEYFPFDWQNCSMQFRSYTYDSTEI
DVQYALNLRGQEIREIQLDEAFTEGGEWYIKHRPSRKVMLDDEYEGMVFYLIIERKPLYY
VLNIILPCILITIIAIFNFYLPPDAGEKMGLSINVLLTLTVFLLLLADKIPETSLGVPII
VNYIMLTMILVTFSVILSVVVLNLHHRSPNTHQMPMWVRKIFIHLLPPYLCMMRPKVEAP
LYLEALPRREKKVTTVSKVADEYFIRKPDMSVLFPKPNRFHSEGLCTDLRKFIDGPSSYL
SLPEELKSAIEAITYIAEALQAEKDYEALKKDWQYVAMVVDRMFLWIFVIFTTVGTLAIF
AEASFNRAPANPFP
>Takifugu rubripes_CHRNB1b(ENSTRUP_10240)
TSYLLFTQLIFGVLLLLAGASEVEKTLMKTLFSNYTLKVRPAISPEQRVVVRVGMILSSF
VGLNMKNEEMSTIVVMNLEWTDYRLSWSPKQYGGIEVLRIPSGKVWLPDIVLINNNDGVF
HVALHVHVQVYSNGRVTWTPPALYCSSCGVKVEYFPFDWQNCSMQFRSYTYDSTEIDVQY
ALNLRGQEIREIQLVYNISPEGGEWYIKHRPSRKVMLDDEYEGMVFYLIIERKPLYYVLN
IILPCILITIIAIFNFYLPPDAGEKMGLSINVLLTLTVFLLLLADKIPETSLGVPIIVNY
IMLTMILVTFSVILSVVVLNLHHRSPNTHQMPMWVRKIFIHLLPPYLCMMRPKVEAPLYL
EALPRREKKVTTVSKVADEYFIRKPDMSVLFPKPNRFHSEGLCTDLRKFIDGPSSYLSLP
EELKSAIEAITYIAEALQAEKDYEALKKDWQYVAMVVDRMFLWIFVIFTTVGTLAIFAEA
SFNRAPANPFP
>Tetraodon nigroviridis_CHRNB1(ENSTNIP_8624)
AFEVESALLKNLFSNYTLKVRPAVSPEQRVVVRVGMILSSFVGLNMKNEEMSTIVVMNLE
WTDYRLSWSPKDYDGIEVLRIPSGKIWLPDIVLINNNDGVFEVALQVHVQVYSNGRVTWT
PPALYCSSCGVKVEYFPFDWQNCSMQFRSYTYDSTEIDIQYALDSKGREIKEIQLDEAYT
EGGEWYIKHRPSRKVMLDDEYEGMVFYLIIERKPLYYVLNIILPCILITIIAIFNFYLPP
DAGEKMGLSINVLLTLTVFLLLLADKPETSLGVPIIVNYIMFTMILVTFSVILSVVVLRL
HHRSHNTHQMPMWVRRIFIHLLPPYLCMMRPQVETPLYLEVLPRREKKIPASSKVADEYF
IRKPDLSVLFPKPNRFHSDGLCTDLRKFIDGPSSYLSLPEELKSAIEAITYIAEALQAEK
DYEALKKDWQYVAMVVDRMFLVLFVIFTTVGTLAIFTQASFNRSPGNPFPVTPDTWFL
>Gasterosteus aculeatus_CHRNB1(ENSGACP_26349)
PLCPTGASDMEKTLLKKLFTDYNLKVRPASSPEERVVVRVGMVLSSFVGLNMKNEEMSTI
VVMNLEWTDHRLSWKREEYDGIEVMRIPAGKVWLPDIVLINNNDGVFDVALHVHVQAYSN
GRVTWTPPALYCSSCGVKVTYFPFDWQNCTMQFQSYTYDSTEIDVQYALDSKRNEIREIQ
LDEAYTEGGEWTIKHKPCRKNMNDDQYEVMTFYLIIERKPLYYVLNIILPCILITIIAIF
NFYLPPDAAPGEKMGLSINVLLTLTVFLLLLADKIPETSLGVPIIVNYIMFTMILVTFSV
ILSVVVLNLHHRSPSTHMMPMWVRKIFIHLLPPYLYMLRPKVETPLSLEFMPRREKKVFT
ISKADEYFIRKPDSSILFPKPNRFHPEGMCTDLRKYIDGPSSYLTLPDELKSAIEAITFI
AEALQAEKDFEALREDWQYVAMVVDRMFLWIFVIFTTVGTLAIFADASFHRTPTDPFK
>Oryzias latipes_CHRNB1(ENSORLP_4440)
MTLLFPVGHLGVPYRSRLLGAAQVEQALMKSLFSDYNLKVRPAHVPESRVVVRVGMILSS
FVGLNMKNEEMSTTVVMNLEWTDYRLTWNPKQHDGIKMLRVPSGKVWLPDIVLINNNDGV
FDVALRVHVLVYSDGRITWTPPALYLSSCGVKVTYFPFDWQNCTMQFRSYTYDSTEIDLQ
YALDSKGKEIREIQLDEGFSESGEWHIRHKPSRKIMKDDLYEEMTFYLIIERKPLYFNFY
LPPDAGEKMGLSINVLLTLTVFLLLLADKIPETSLGVPIIVKYIMFTMILVTCSVILSVV
VLNLHHRSPNTHMMPMWIRKIFLHMLPPYLFMRRPKQENLQYLESVPRREMKVMAISKAA
DEYFIRKPDSSILFPKPNRFHSDGMYTDLRKFIDGPSTYLALPDELKTAIDAITYIAEAL
QAEKDYEALKEDWQFVAMVVDRMFLWIFVVFTTLGTLAIFIDASFNHTPKDPFK
>Homo sapiens_CHRNE(ENSP_293780)
MARAPLGVLLLLGLLGRGVGKNEELRLYHHLFNNYDPGSRPVREPEDTVTISLKVTLTNL
ISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSELVWLPEIVLENNIDGQF
GVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSLIFRSQTYNAEEVEFTF
AVDNDGKTINKIDIDTEAYTENGEWAIDFCPGVIRRHHGGATDGPGETDVIYSLIIRRKP
LFYVINIIVPCVLISGLVLLAYFLPAQAGGQKCTVSINVLLAQTVFLFLIAQKIPETSLS
VPLLGRFLIFVMVVATLIVMNCVIVLNVSQRTPTTHAMSPRLRHVLLELLPRLLGSPPPP
EAPRAASPPRRASSVGLLLRAEELILKKPRSELVFEGQRHRQGTWTAAFCQSLGAAAPEV
RCCVDAVNFVAESTRDQEATGEEVSDWVRMGNALDNICFWAALVLFSVGSSLIFLGAYFN
RVPDLPYAPCIQP
>Mus musculus_CHRNE(ENSMUSP_99616)
MAGALLGALLLLTLFGRSQGKNEELSLYHHLFDNYDPECRPVRRPEDTVTITLKVTLTNL
ISLNEKEETLTTSVWIGIDWHDYRLNYSKDDFAGVGILRVPSEHVWLPEIVLENNIDGQF
GVAYDSNVLVYEGGYVSWLPPAIYRSTCAVEVTYFPFDWQNCSLIFRSQTYNAEEVEFIF
AVDDDGNTINKIDIDTAAFTENGEWAIDYCPGMIRRYEGGSTEGPGETDVIYTLIIRRKP
LFYVINIIVPCVLISGLVLLAYFLPAQAGGQKCTVSINVLLAQTVFLFLIAQKIPETSLS
VPLLGRYLIFVMVVATLIVMNCVIVLNVSLRTPTTHATSPRLRQILLELLPRLLGSSPPP
EDPRTASPARRASSVGILLRAEELILKKPRSELVFEGQRHRHGTWTAALCQNLGAAAPEI
RCCVDAVNFVAESTRDQEATGEELSDWVRMGKALDNVCFWAALVLFSVGSTLIFLGGYFN
QVPDLPYPPCIQP
>Bos taurus_CHRNE(ENSBTAP_42804)
MAGALLCALLLLQLLGRGEGKNEELRLYHYLFDTYDPGRRPVQEPEDTVTISLKVTLTNL
ISLNEKEETLTTSVWIGIDWQDYRLNYSKGDFGGVETLRVPSELVWLPEIVLENNIDGQF
GVAYEANVLVSEGGYLSWLPPAIYRSTCAVEVTYFPFDWQNCSLVFRSQTYNAEEVEFVF
AVDDEGKTISKIDIDTEAYTENGEWAIDFCPGVIRRHDGDSAGGPGETDVIYSLIIRRKP
LFYVINIIVPCVLISGLVLLAYFLPAQAGGQKCTVSINVLLAQTVFLFLIAQKTPETSLS
VPLLGRYLIFVMVVATLIVMNCVIVLNVSLRTPTTHAMSPRLRYVLLELLPQLLGSGAPP
EIPRAASPPRRASSLGLLLRAEELILKKPRSELVFEQQRHRHGTWTATLCQNLGAAAPEI
RCCVDAVNFVASSTRDQEATGEEVSDWVRMGKALDSICFWAALVLFLVGSSLIFLGAYFN
RVPQLPYPPCM
>Danio rerio_CHRNE(ENSDARP_116514)
MAVAERFGRTCVVAIALLATVLQVTGNEESQLIADKFKNYSKNIRPARHADEKVKVQVKL
TLTNLISLNEKEETLTTNVWIEIQWHDYRLAWNTSEYHDIEQIRVPYYTVWLPDIVLENN
IDGKFDVAYYANVLISSDGSMYWLPPAIYRSTCAIEITYFPFDWQNCTLVFRSQTYSANE
IDIVLAEDENGKPIEWVDIDPEAFTENGEWAIKHRPARKLTNQRYSPDDLEYQEVYYNII
IQRKPLFYVINIILPCSLISSLVVLAYFLPAKAGGQKLTVSISVLLAQTVFLILISQKIP
ETSLSVPLIGKYLIFVMSMTTLIVTNCIIVLNYSLRSPSTHNMSQSIKHIFLEVVPRYLG
MAPFVDEGDQGGVYEMRERRRSSFGLMQRAEEYVLKQPRSEMMFDKQRERHGLMRTIVDE
IDVSSTANLYKSLAKTAPEIKECVDACNFIAESTKQQNDTGSEMESWVLIGKMIDKVCFW
AAISLFSIGTIAIFLMGHYNQAPEYPFAWENKKYVPE
>Takifugu rubripes_CHRNE(ENSTRUP_41477)
SLLGSQSLVSLFRAVQSNEETELIKDLFKDYNKNIRPVVHPEDKVEVQIKLTLTNLISLN
EKEETLTTNVWIEIQWLDYRLSWNESKYYGIQVIRVPCKTVWLPDIVLENNIDGKFDVAY
YANVLISSNGWMYWLPPAIYRSTCSIEITYFPFDYQNCTLAFRSQTYSANEVDLILALTE
ENGTIEWVDIDPEAFTENGEWAIVHRPARKMVNMRYSPDDLEYQEILFNLVIQRKPLFYI
INLILPCSLISSLVVLAYFLPAQAGGQKLTVSISVLLAQTVFLFLIAQKVPETSLSVPLI
GKYLIFVMCVTTLIATNQIVVLNFSLRSPNTHTMSQTIKHVFLEMVPRFLCMPPLVDESE
ATTEVNGIRERRRSSFGLMQRAEEYVLKQPRSEMMFDKQRERHGLTTANLYKSLAQAAPE
IKQCVDACNFIADSKRQQNTIGSEIESWVLIGKMIDKVCFWAAILLFIIGTVAIFLMGHF
NRAPDFPFPGQNKK
>Tetraodon nigroviridis_CHRNE(ENSTNIP_14726)
NEETELIKDLFKDYNKKIRPVVHPEDKVEVQIKLTLTNLISLNEKEETLTTNVWIEIQWI
DYRLSWNESEYYGINIIRVPCKTVWLPDIVLENNIDGKFDVAYYANVLVSSNGGMYWLPP
AIYRSTCAIEITYFPFDYQNCTLAFRSQTYSANEVELILTIGEKNETIEWVDIDPEAFTE
NGEWAIVHRPARKVINTRYSPDDLEYQEIMFNLVIQRKPLFYIINVILPCSLISSLVVLA
YFLPAQAGGQKLTVSISVLLAQTVFLFLIAQKVPETSLSVPLIGKYLIFVMCVTTLIATN
QIVVLNFSLRSPSTHTMSQTIKHVFLELVPRLLCMPPLVDEGEATAVVNGIRERRRSSFG
LMQRAEEYVLKQPRSEMMFDKQRERHGLTRSIVDNIDVTSTANLYKSLAQAAPEIKQCVD
ACNFIADSIRQQNTIGSEIENWVLIGKMIDKVCFWAAILLFIIGTVAIFFMGHFNRAPDF
PFPGEDKKYVPS
>Gasterosteus aculeatus_CHRNE(ENSGACP_26955)
MAESRFWIFFGVVAVLGTLTARVQCNEESELIRDLFKGYNKNIRPVVHPEDKLTIQIKLT
LTNLISLNEKEETLTTNVWIEIQWVDYRFVWNTSNYHGIDVIRVPCKTIWLPDIVLENNI
DGKFDVAYYANVLISYDGSMYWLPPAIYRSTCAIEITYFPFDYQNCTLAFRSQTYSANEV
DLILAVGDEMETIEWVDIDPQAFTENGEWAIVHRPGRKMINPRYTPDDLEYQEILFNLVI
QRKPLFYIINIILPCSLISSLVVLAYFLPAQAGGQKLTVSISVLLAQTVFLFLIAQKIPE
TSLSVPLIGKYLIFVMSVTTLIATNQIVVLNFSLRSPSTHTMSNTIKHVFLEMVPRFLGM
PPLVDDTEVTTVVNGVRERRRSSFGLLQRAEEYVLKQPRSEMMFDKQRERHGLTRSIVDD
MDVSSTANLYKSLAQAAPEIKQCVDACNFIAESTRQQNSIGSEIESWVLIGKMIDKVCFW
AAISLFIIGTVWIFLTGHFNRAPEFPFPGQSKKYVPS
>Oryzias latipes_CHRNE(ENSORLP_10079)
MPVFSSPLLQYIMIEIVHCNEESQLIGDLFRNYNKNIRPVEHPEDKVQVMIKLTLTNLIS
LNEKEETLTTNVWIEIQWTDYRLVWNTSQYYGIKTIRVPYNTVWLPDIVLENNIDGKFDV
AYYANVLISNEGWMYWLPPAIYRSTCAIEITYFPFDYQNCTLAFRSQTYSAKEVDLVLAT
GDEDVTIEWVDIDPEAFTENGEWAIVHRPARKVINTRYSPDDLEYQEIIFNLVIQRKPLF
YIINVILPCSLISSLVVLAYFLPAQAGGQKLTVSISVLLAQTVFLFLIAQKTPETSLAVP
LIGKYLIFVMCVTTLIATNQIVVLNFSLRSPSTHTMSYSIKHLCLEMVPRFLGMSPLVDD
SEVTAEVNGIRERRRSSFGLMQRAEEYVLKQPRSEMMFDKQRERHGLTRSIVDNIDVSST
ANLYKSLAQAAPEIKQCVDACNFIAESTKQQNDIGSVXESWVLIGKMIDKVCFWAAMLLF
SGTVGIFLTGHVNKAPEFPFPGEDKKYVP
>Homo sapiens_CHRNA5(ENSP_299565)
MAARGSGPRALRLLLLVQLVAGRCGLAGAAGGAQRGLSEPSSIAKHEDSLLKDLFQDYER
WVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDDYGGIKV
IRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSSCTIDVTFFPFD
LQNCSMKFGSWTYDGSQVDIILEDQDVDKRDFFDNGEWEIVSATGSKGNRTDSCCWYPYV
TYSFVIKRLPLFYTLFLIIPCIGLSFLTVLVFYLPSNEGEKICLCTSVLVSLTVFLLVIE
EIIPSSSKVIPLIGEYLVFTMIFVTLSIMVTVFAINIHHRSSSTHNAMAPLVRKIFLHTL
PKLLCMRSHVDRYFTQKEETESGSGPKSSRNTLEAALDSIRYITRHIMKENDVREVVEDW
KFIAQVLDRMFLWTFLFVSIVGSLGLFVPVIYKWANILIPVHIGNANK
>Xenopus tropicalis_CHRNA5(ENSXETP_51511)
MPWCAEYLLWLFLCLDILHGACGISEPSYIAKSEDRLFKYLFQQQDYQRWVRPVEHLNDT
VKVKFGLAITQLVDVDEKNQLMTTNVWLKQEWVDVKLRWDPNEFAGITSIRVPSDSIWIP
DIVLYDNADGRFEGSVTKAVVRYDGTINWTPPANYKSSCTIDVTFFPFDLQNCSMKFGSW
TYDGSQVDIILEDYHVDKRDFFDNGEWEIVNATGNKGNRTDGCCFYPYITYSFIIKRLPL
FYTLFLIIPCIGLSFLTILVFYLPSNEGEKISLCTSVLVSLTVFLLVIEEIIPSSSKVIP
LIGEYLVFTMIFVTLSIVLTVFAINIHNRSSATHNAMAPWVRKIFLHKLPKLLCMRSHVD
RYFTRKDETGKVRGPESSRNTLEAALDSIRYITRHVMKEHEVQEVVEDWKFVAQVLDRMF
LWTFLLVSVIGSLFLFIPVIHKWANIIVPVHIGNMYGDKNT
>Danio rerio_CHRNA5(ENSDARP_136216)
MVTALSLVRALLPLVCSAVLCSAIGPPMLSSYAKTEDKLFKHLFSNYQKWVRPIEDLNTT
IQVKFGLAISQLVDVDEKNQLMTTNVWMKQEWTDLKLRWDPDHYLGITSIRVPSDSIWIP
DIVLYDNADGNFEATVTKAVVRFDGTISWTPPANYKSACTIDVTFFPFDLQNCSMKFGSW
TYDGSQVDILLEDVHVDKRDYFDNGEWEIVKATGNRGLRRDGTFFYPSITYSFIIRRLPL
FYTLFLIIPCIGLSFLTVLVFYLPSNGGEKISLCTSVLVSLTVFLLVIEEIIPSSSKVIP
LIGEYLVFTMIFVTLSIVITVFAINIHHRSSSTHHSMAPWVRRIFLHHLPRLLCMRSHVD
RYATSAGTRTGGLGYGKSLSQDTNQLDAEHNLQAALESIRYITRHVVKENEVREVVQDWK
FVAQVLDRVFLWAFLLVSLLGSALLFIPVIYKWASIIVPSYAEITS
>Takifugu rubripes_CHRNA5(ENSTRUP_13990)
STEIRISMTVNLWVITVFLHLLEVPKLSSCAKAEDKLFKYLFGNYQKWVRPVDHLNQTIR
VKFGLAISQLVDVDEKNQRMTTNVWMKQEWTDMKLRWNPEEYAGITIIRVPSDRIWRPDV
VLYDKSSDGRFEGTITKAVVKYDGTITWTAPANYKSACTIDVTFFPFDLQNCSMKFGSWT
YDGSQVDIILEDFHVDKRDYFDNGEWEIVKATGSRGLRMDGSTSYPTITYFFIIRRLPLF
YTLFLIIPCIGLSFLTILVFYLPSNGGEKISLCTSVLVSLTVFLLVIEEIIPSSSKAIPL
IGEYLVFTMIFVTLSIVITVFAINVHHRSSSTHNDMAPWVRRVFLHHLPKLLCMRSHVDR
YATSGAARTRGLGMAEGSEPELTPLFYTRQNLKAALDSIRYITMHVVKENEVREYPHARG
LSQQVSKSLNSFQAQTCSQTCRFLPSIDMKKKKAKEIHFKVVQDWKFVAQVLDRMFLWAF
LLVSILGSALLFIPVIYKWASIIV
>Tetraodon nigroviridis_CHRNA5(ENSTNIP_14923)
VPKLSSYAKAEDKLLKYLFGNYQKWVRPVDHLNQTIRVKFGLAISQLVDVDEKNQRMTTN
VWMKQEWTDMKLRWSPEEYVGITIIRVPSDRIWRPDVVLYDNSDGRFEGTVTKAVVKHDG
TITWTAPANYKSACTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDFHVDKRDYFDNG
EWEIVKATGSRGLRTDGSASYPTITYFFIIRLPLFYTLFLIIPCIGLSFLTILVFYLPSN
GGEKISLCTSVLVSLTVFLLVIEEIIPSSSKAIPLIGEYLVFTMIFVTLSIVITVFAINV
HHRSSSTHNDMAPWVRRVFLHRLPKLLCMRHVDRYATSGASRARALGMAESTPELTPLLY
SRQSLKAALDSIRYITMHVVKENEVREVVQDWKFVAQVLDRMFLWAFLLVSILGSAILFI
PVIYKWASIIVPNHETMVFGN
>Gasterosteus aculeatus_CHRNA5(ENSGACP_21887)
MCHSLRVPKLSSFAKAEDKLFKYLFGNYQKWVRPVEYLNQTISVKFGLAISQLVDVDEKN
QQMTTNVWMKQEWIDRKLRWNPDDYLGITTIRVPSNRIWLPDVVLYDNSDGRFEATVTKA
VVKYNGTISWTPPANYKSACTIDVTFFPFDLQNCSMKFGSWTYDGSQVDITLEEFHVDKK
DYFDNGEWEIVKATGSRGLRTDSSSTYPTITYFFIIRRLPLFYTLFLIIPCIGLSFLTIL
VFYLPSNGGEKISLCTSVLVSLTVFLLVIEEIIPSSSKAIPLIGEYLVFTMIFVTLSIVI
TVFAINIHHRSSSTHHNMAPWVRRIFLHRLPKLLCMRSHADRYATAGVARTGGAEREGKM
KDSAPELTSLLYTKHNLQAALESIRYITMHVVKENEVREVVQDWKFVAQVLDRMFLWAFL
LVSILGSALLFIPVIYKWANIIVPKHFGS
>Oryzias latipes_CHRNA5(ENSORLP_24913)
VPKLSSYAKAEDTLFKHLFGTYQKWVRPIEYLNQTIPVKFGLAISQLVDVDEKKQLMTTN
VWLKQEWIDMKLRWKPEDYLGITTIRVPSDRIWLPDVVLYDNSDGRFEGTVTKAVVKYDG
TISWNPPANFKSACTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDFHVDKKDYFDNG
EWEIVKATGSRGLRTDGSTSYPTITYFFIIRRLPLFYTLFLIIPCIGLSFLTILVFYLPS
NGNEKISLCTSVLVSLTVFLLVIEEIIPSSSKAIPLIGEYLVFTMIFVTLSIIITVFAIN
IHYRSSSTHHDMAPWVRRIFLHRLPKLLCMRSHVDRYATAGLAGKGKVTVQEKTKDSTPD
LTHILHTRHNLQTALESIRYITMHVVKENQVREVVQDWKYVAQVLDRMFLWAFFLVSVLG
SALLFVPVIYKWASIIVPDYAGS
>Ciona intestinalis_(ENSCINP_4364)
MGSRCWLIAVCLCYVIRECLSAHAEEKLLRHLLDPVRYNKLIRPSESITSKVDVHFDLII
SQLIGINEREQYMITKVWLPQVWVDKRLSWQPMRYENITKVQLPSNMIWLPDVVLYNNAD
GMYEVSLQSNAIILNNGTVTWMPPAIYKSACKIKVRHFPFDEQNCTMMFRSWTYNRLDIE
LKLKNPNATLDDFTPSGEWDILQTPGSVNVNPNDETYQDLLYSLIIRRKPLFYTINLIIP
CILITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLIGKYLMFT
MMLVTLSIVASVCVLNIHHRSPSTHTMPPWIRTIFLNHLPPLLGMERPGTDDRCRCKVND
ATYGVDVTELSGSDVIRNRKRGKSEVKLPRDVSSALEGVKFIADHLRAEDENKNVHEDWK
YVAMVIDRMFLFVFVGVCAIGTIGIFIQPFV
>Ciona intestinalis_(ENSCINP_17902)
MINCLLIFLLLPITKTSAAKFESTEGRLANYLLNGYNPQFRPYNKKYENKTFVDVMMTLS
QIISVKEKSQEFTTSVYMQYDWLDDRFGWVPDDYDGITTVRIPCASIWVPRIVLQNSIDG
NFDVSLRTNALIQHDGKVSWLPPALYKSTCTIEVALFPFDWQNCTMVFRSATYDRTEMEF
GIPIDTVYIDLSAFQSNGEWDILQRPVKINSNENDKTYQDITFYFIIRRKPQFYIINLII
PCILMSSLSCFVFYLPSISCEKMTLSISILLGETVFLFLIAQRMPETSLAVPLIAGYLLF
VMILVIISVICSVVVCNVHYRSNTTHSMPDWIVWIFMEKLAPLLKVERPSEEESGACSAR
PRRCSSVSTRKAMKQRSEWKPPSEILFDHQASRLGFRARHYLNEYGMTGINVAAPENGSF
VPPSFKKLPKGFQPAADSIDYIANQKKEENEMGQSQDDWGYVALILDRLLLWVYLATFTL
GTLFFFLQTKFAYYPEKLN
>Ciona savignyi_(ENSCSAVP_750)
ECTSAHAEEELLRHLLDSGRYNKLIRPSQSNFDLIISQLIGINEREQFMITKVWLPQVWV
DERLSWQPTEYENITKVQLPSDMIWLPDIVLYNNADGTYEVSLQSNAIILNNGTVTWMPP
AIYKSACKIKVRHFPFDEQNCTMMFRSWTYDRDDIELKLMNPNATLDDFTPSGEWDILAT
PGMMNLNADDPSYQDLLYSLVIRRKPLFYTVNLIIPCILITSLAILVFYLPSDCGEKMTL
CISVLLALTVFLLLISKIVPPTSLDVPLIGKYLMFTMMLVTFSIIASVCVLNIHHRSPST
HEMSPWIRRTFLQVIPPLIGMQRPGTDQCSYNKYKVDVSDLSGSDVIRKRKQPEVQLSRD
ISSALEGVKLISDHLKAEDRNKNVSFIGYLYILEYLIFRLTRMLIRGYISFIVLLDSPTP
AVHVQFRSQGWIRQHLFNLSSCELVIHEDWKYVAMVIDRMFLFVFVVVCAVGTVSIFLQP
FV
>Ciona savignyi_(ENSCSAVP_1475)
LHTGFILLVLAASAASVLSEFQSSESRLMKRLLNGYNNQFRPYNVEYENKTLVSMGMTLS
QIISVKEKSQELTTSVYMTFDWVDNRFSWDPEEYEGITIIRIPPYAIWSPRIVLQNSIDG
NFDVSVPVMALIKYTGEVQWIPPGLYKSTCTIVVALFPFDWQNCTMVFRSATYDRSEMEF
GLSYGDSIYVDPEAFKENGEWKIVQRPVRINSDSSDPTYQDVTFYLIIRRKPQFYVINLI
IPCILMSSLSCFVFYLPSVSCEKMTLSISVLLGETVFLFLIAQRVPETSLAVPLIAGYLL
FVMILVIISVISSVVVCNVHYRSNTTHSMPDWVVWFFMEKLAPILRVERPSEEESGACSA
RPRRCSSVSARKAMRQRKEWKSPSEIMFDHQASRLGFRRRHVVNHYGMTEVNVASPENDF
EPAAESINYIANQLKEENDSAQSKDDWGYVALILDRILLWIYFAAFSLGTLFFFLQSTFA
YYPEQ
>Ciona savignyi_(ENSCSAVP_3483)
TEEKLFKRLFDDYNIWIRPVANSNQSVLIAFELFVSQLVKVDEINQIMMTNLWLKQEWND
NKLRWRPEDYGGVKYLRVPSEFIWKPDIVLYNTAVGKFQVDQNTKALLRYNGDVSWMPPA
IFKSSCSIDVTYFPFDTQNCTMKFGSWTYDKARVNLVIKGNEANRKEYWESGEWELLDVL
GYRHERKYNCCPEIYPDVTYSFHIRRLPLFYMINLIIPCLLISFLTVLVFYLPSDCGEKI
TLCISVLLSLTVFLLVITEIIPSTSLVIPLIGQYLLFTMIFVTLSIVITVFVLNVHFRSE
NTHTMPPWVRRVFLECLPKASCFSHLFHSSISSHNHNNVNKSLAHSATSLTHHSTSPTHN
TTTAICHMNRVSNAEKTEKTPDSALPKEVQRAIESVMYIANHLKVEDESTEIENDWKYVG
MVIDRIFLWIFIVVCVLGTTGIFLRPLLDDTHVG
>Branchiostoma floridae_(XP_002594600)
MLVTKVNVSFCRSHTETLAAEAEERLVQRLFNESRYNPLIRPARYNGEKVLVHFRLSISQLINVDEKNQK
MKTNVWLHQEWFDYRLSWDPREYDNIKVIRVPSEIVWRPEIVLFNNANGQYDVQLMPKCLIYSGGNITWI
PPAIYESACQIDVRFFPFDQQNCSMKFASWTYDGTELDLELKDTNAVMDDFKKNGEWDILRLPGRKSSHA
GDPLPYVYFDFILMRRPLFYTINLIIPCILITSLSVLVFYLPSDCGEKITLSISVLLALTVFLLLIADII
PPTSLDVPLIGKYIMFTMIFVTFTIVTTVYILNVHHRHPSTHTMPPWVRTVFLDKLPRLLLMKRPNQCRK
YALRVSESSARNPHEDFPEDHTDSPYYSPRTRPAHTHYKQIDLPPEVPSDLPPELKKAVKNVRYIADYFR
SHDQDLSISEDWKYVAMVIDRIFLWTFVSVCFIGTLGLFLQPLL
>Branchiostoma floridae_(XP_002603628)
MFLPGGVATQSEERLFRDLFRDYNKWIRPVANISNIVVIEFGLAIAQLLDVDEKNQIMTTNVWLKQKWKD
SKLCWDPDEYHGVSVIRVPSDMIWLPDIVLYNNADGNYAVKHNTKAQISSDGMVTWEPPAVYKSSCEIEV
TYFPFDQQNCSMKFGSWTYDGFQIDLMMMDDHVDQGGFSESGEWVIIDAPGQKNIIKYECCEEVYPDITF
FFVIRRLPLFYTINLIVPCALISFLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPATSIVIPV
IGEYLLFTMIFVTLSIVITVFVLNIHYRSPSTHRMPVWVRKIFIDILPRLLSDVYDYESKTLPRMTTPKM
RSRHGAKVSVTNVSGNPGVGGAEKYNTCDSRPSQSQARAQFQSYQYSPDILRAAQGVNYIAETLRAKDEA
DSVNEDWKYVAMVIDRIFLWIFVSMCILGTIGLFLQPLPGFIS
>Drosophila melanogaster_(FBpp0306936)
MGSVLFAAVFIALHFATGGLANPDAKRLYDDLLSNYNRLIRPVGNNSDRLTVKMGLRLSQ
LIDVNLKNQIMTTNVWVEQEWNDYKLKWNPDDYGGVDTLHVPSEHIWLPDIVLYNNADGN
YEVTIMTKAILHHTGKVVWKPPAIYKSFCEIDVEYFPFDEQTCFMKFGSWTYDGYMVDLR
HLKQTADSDNIEVGIDLQDYYISVEWDIMRVPAVRNEKFYSCCEEPYLDIVFNLTLRRKT
LFYTVNLIIPCVGISFLSVLVFYLPSDSGEKISLCISILLSLTVFFLLLAEIIPPTSLTV
PLLGKYLLFTMMLVTLSVVVTIAVLNVNFRSPVTHRMAPWVQRLFIQILPKLLCIERPKK
EEPEEDQPPEVLTDVYHLPPDVDKFVNYDSKRFSGDYGIPALPASHRFDLAAAGGISAHC
FAEPPLPSSLPLPGADDDLFSPSGLNGDISPGCCPAAAAAAAADLSPTFEKPYAREMEKT
IEGSRFIAQHVKNKDKFESVEEDWKYVAMVLDRMFLWIFAIACVVGTALIILQAPSLYDQ
SQPIDILYSKIAKKKFELLKMGSENTL
>Apis mellifera_(NP_001011575)
MFKMQILTLGVLFNTLHIIYSVAGLKIFEANPDTKRLYDDLLSNYNRLIRPVMNNTETLTVQLGLKLSQL
IEMNLKNQVMTTNVWVEQRWNDYKLKWNPEEYGGVEMLYVPSENIWLPDIVLYNNADGNYEVTLMTKATL
KYTGDVSWKPPAIYKSSCEINVEYFPFDEQSCIMKFGSWTYNGAQVDLKHMKQEAGSNLVAKGIDLSDFY
LSVEWDILEVPASRNEEYYPCCTEPYSDITFNITMRRKTLFYTVNLIIPCVGITFLTVLVFYLPSDSGEK
VSLCSSILLSLTVFFLLLAEIIPPTSLAIPLLGKYLLFTMILVTLSIWITVCVLNVHFRSPSTHNMSPWV
RQVFLNWMPRLLMMRRTPYSTPEYDDTYMDSGYTNEIDFSFPDSVSDYPLELKGSPDGFESVTSQYKNIR
EDDARHIPHASVTDSENTVPRYLSPDVISALKGVRFIAQHIKNADKDNEVIEDWKFVAMVLDRLFLWVFT
LACTAGTLGIIFQAPSLYDTREPVDQQLSGISPRNYMYPNIDISPEG
>Anopheles gambiae_(XP_311918)
MGSVLLTAVFIALQFATGLANPDSKRLYDDLLSNYNRLIRPVGNNSDRLTVKMGLRLSQLIDVNLKNQIM
TTNVWVEQEWNDYKLKWNPDDYGGVDTLHVPSEHIWLPDIVLYNNADGNYEVTIMTKAILHHTGKVVWKP
PAIYKSFCEIDVEYFPFDEQTCFMKFGSWTYDGYMVDLRHLQQTPDSDNIDIGIDLQDYYISVEWDIMKV
PAVRNEKFYSCCEEPYPDIIFNITLRRKTLFYTVNLIIPCVGISFLSVLVFYLPSDSGEKISLCISILLS
LTVFFLLLAEIIPPTSLTVPLLGKYLLFTMMLVTLSVVVTIAVLNVNFRSPVTHRMAPWVHRVFIELLPK
VLCIERPKKEDEPSDNDDQTPTDVLTDVFQVPPDVEKYVGFCGKEYGTDFDIPALPPSRFDVAASGGVGP
CFGEPPLPALPLPGGDDDLFSPTGNGDMSPTCCGDLSPTFEKPLLREMEKTIEASRFVAQHVRNKDKFES
VKEDWKYVALVLDRLFLWIFTIACVLGTCLIILQAPSLYDNTQPIDAMYSKIAKKKMELLKMGSENV
>Caenorhabditis elegans_(T08G11)
MRTNRLSWILVLSVVIFLVIINTINASDDEERLMVDVFRGYNSLIQPVRNSSELPLIVKM
ALQLVLLINVDEKDQVMHTNVWLTLQWHDFQMKWNPVNYGEIKQIRVSPDKVWLPDIVLF
NNADGNYEVSFMCNVVINHKGDMLWVPPAIYKSSCIIDVEFFPFDEQVCTLVFGSWTYNE
NEIKLEFVQAELVDVSEYSASSIWDVIDVPASLVNKRSRIEFQVRIRRKTLFYTVVLIIP
TVLMAFLSMAVFFLPTDSGEKITLTISVLLSIVVFLLLVSKILPPTSSTIPLMAKYLLLT
FVLNVITILVTVIIINVYFRGPRTHRMPQWVRVVFLQFLPKLVCMKRPKSASERSAVRSG
MAQLPGVGQFTLSPSAHHPLCPSADDRTTTIRNTASNETSAYYPLSTDALRAIDAIEYIT
EHLKRDEQHKSFRDDWKYVAMIIDRLLLYVFFGITVGGTCGILFSAPHVFQRIDQQEMLD
RLKEKYDTASNIP
>Trichoplax adhaerens_(XP_002111826)
MVATAQKNCYIYAILFASILSHSICNAQKTLFSVLEQQQTQNAVMISTNGDAIIAGLLPAHYNYEDGKHK
CSELDTYGIHLMMAMIFAINDINEQSNLLPDVKLGYDIRDTCHNSLRVSKEIMALLMQYLPFKEGKYDGF
FCEKIKYDEANEETVRTYGPIIGVIGTTMSDSTIATANTIGNFGVIEITPSALAVTQSDNQPPNLYSTQP
SFYDHLVVISKIIIALDMTRICLITIEPPETSYRMDLLRTILQDAKICIAQEFSITGDRMSLAMARVIQN
LKANNKLQVVVLLGPYEKGVRFMKEAERQNLTGRTWIGAGEWVKSPAIYSIRKEVMGGLLAVSTQTFRSV
LITKHLENYVTSDTRNVHLDQLWKKLYNCTPNEENCEVRLGSYEIIDEKKSSCEYYQSELNEDIIYVIDA
VYAIAHALHQTLNCTIEFCNSVETFNHTIFNYHLQRVEFSNHANQPVEFQQNKGVRHILIQNLHHDDNCS
HFVEVARWNPFESEMIMDTNKIRWRNGESTTIPTEVYETACTPGDRKHSFDQESCYYVCLKCGPSLVSNG
TTSQCFKCSPGFKPTNNRSACQEIPPTKLDWRNPVNLTILIFTLLSMLTLLFIVIIFFKYSNTPIVKASN
KIMSHIQLLSVALLFILGGSYQFAVTTSLCWFQFAICSVSFPLCEACLLAKTKHVANVFTLSSRIQKVDK
SSRLQSRWCKSLIPILFVLSITAIPIIIWLIFTIIDPPNAIPDYRYENEVHILCSSKLHLGLGLVVGFTL
VLAIICTILAWKTRKLPDNFSEARYIFICSFSTLVIVALSVPGYYSTVGLLQATFASIAVITFGLSILLL
LFIPKIYTILFRPDLNTKEAMLRSIQEFTFGADTRIHTKPK
>Amphimedon queenslandica_(XP_011410551)
MSSSRSLSSSRSKSHLSKSSKFESTAELPSEVMVNTPEQLSWQVLSQTQVARFKALSPTELTKELSTVLS
LSKHEEDLQQAAILDYYVSSFVFAQEKDFTDEQLSSFFTIIHKLLANIREKRTTLQDNLNELKSYFAGVG
VSDQTCLKCFTPKVAMATISYIHTSLVQHYTLFEYILQEKQEDEFIQTQLLVSLPPDSSTLSPPPLEESV
TEDFYNRLVSTAPAGSPSQTQLGSPTTHSPPHSIQGTDMSSPTGAIPPTLLLNLRPEDVKMMTEKLLEET
VTPYQDEMLRKLVDRETSYKSKLDKLEKSLT