>Homo sapiens_KCNQ3
MGLKARRAAGAAGGGGDGGGGGGGAANPAGGDAAAAGDEERKVGLAPGDVEQVTLALGAG
ADKDGTLLLEGGGRDEGQRRTPQGIGLLAKTPLSRPVKRNNAKYRRIQTLIYDALERPRG
WALLYHALVFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGC
CCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLRM
DRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEF
ETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQ
EQHRQKHFEKRRKPAAELIQAAWRYYATNPNRIDLVATWRFYESVVSFPFFRKEQLEAAS
SQKLGLLDRVRLSNPRGSNTKGKLFTPLNVDAIEESPSKEPKPVGLNNKERFRTAFRMKA
YAFWQSSEDAGTGDPMAEDRGYGNDFPIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRP
YDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTFPSQQSPR
NEPYVARPSTSEIEDQSMMGKFVKVERQVQDMGKKLDFLVDMHMQHMERLQVQVTEYYPT
KGTSSPAEAEKKEDNRYSDLKTIICNYSETGPPEPPYSFHQVTIDKVSPYGFFAHDPVNL
PRGGPSSGKVQATPPSSATTYVERPTVLPILTLLDSRVSCHSQADLQGPYSDRISPRQRR
SITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFGPNGGSSWMREKRYLAEGETDT
DTDPFTPSGSMPLSSTGDGISDSVWTPSNKPI

>Macaca mulatta_KCNQ3
XGDAAAAGDEERKVGLAPGDVEQVTLALGAGADKDGTLLLEGGGRDEGQRRTPQGIGLLA
KTPLTRPVKRNNAKYRRIQTLIYDALERPRGWALLYHALVFLIVLGCLILAVLTTFKEYE
TVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIAS
VPVVAVGNQGNVLATSLRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGF
LTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPKTWEG
RLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWRYYATN
PNRIDLVATWRFYESVVSFPFFRQLEAASSQKLGLLDRVRLSNPRGSNTKGKLFTPLNVD
AIEESPSKEPKPVGLNNKERFRTAFRMKAYAFWQSSEDAGTGDPTAEDRGYGNDFPIEDM
IPTLKAAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMI
FTPGPPSTPKHKKSQKGSAFTFPSQQSPRNEPYVARPSTSEIEDQSMMGKFVKVERQVQD
MGKKLDFLVDMHMQHMERLQVQVTEYYPTKGTSSPAEAEKKEDNRYSDLKTIICNYSETG
PPEPPYSFHQVPIDKVSPYGFFAHDPVNLPRGGPSTGKVQAAPPSSATTYAERPTVLPIL
TLLDSRVSCHSQADLQGPYSDRISPQQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQ
DRDDYVFGPNGGSSWMREKRYLAEGETDTDTDPFTPSGSMPLSSTGDGISDSVWTPSNKP
I

>Mus musculus_KCNQ3
MGLKARRAAGAAGGGGGEGGGGGGGAANPAGGDSAVAGDEERKVGLAPGDVEQVTLALGA
GADKDGTLLLEGGGREEGQRRTPQGIGLLAKTPLSRPVKRNNAKYRRIQTLIYDALERPR
GWALLYHALVFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAG
CCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLR
MDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEMDAQGEEMKEE
FETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKV
QEQHRQKHFEKRRKPAAELIQAAWRYYATNPNRLDLVATWRFYESVVSFPFFRKEQLEAA
ASQKLGLLDRVRLSNPRGSNTKGKLFTPLNVDAIEESPSKEPKPVGLNNKERFRTAFRMK
AYAFWQSSEDAGTGDPMAEDRGYGNDFLIEDMIPTLKAAIRAVRILQFRLYKKKFKETLR
PYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTYPSQQSP
RNEPYVARAATSETEDQSMMGKFVKVERQVHDMGKKLDFLVDMHMQHMERLQVHVTEYYP
TKGASSPAEGEKKEDNRYSDLKTIICNYSETGPPDPPYSFHQVPIDRVGPYGFFAHDPVK
LTRGGPSSTKAQANLPSSGSTYAERPTVLPILTLLDSCVSYHSQTELQGPYSDHISPRQR
RSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFGPSGGSSWMREKRYLAEGETD
TDTDPFTPSGSMPMSSTGDGISDSIWTPSNKPT

>Bos taurus_KCNQ3
MGLKARRPAGAAGGGGDGGGGGGGAANPAGGDAAAAGDEERKVGLAPGDVEQVTLALGAG
ADKDGTLLLEGGGRDEGQRRTPQGIGLLAKTPLSRPVKRNNAKYRRIQTLIYDALERPRG
WALLYHALVFLIVLGCLILAVLTTFREYETVSGDWLLLLETFAIFIFGAEFALRIWAAGC
CCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLRM
DRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEF
ETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQ
EQHRQKHFEKRRKPAAELIQAAWRYYATNPNRIDLVATWRFYESVVSFPFFRKEQLDPAA
SQKLGLLDRVRLSNPRGSNTKGKLFTPLNVDAIEESPSKEPKPVGSNNKERFRTAFRMKA
YAFWQSSEDAGTGDPTAEDRGYGNDFLIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRP
YDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQRGAAFTYPSQQSPR
NEPYVARPSTSETEDQSMMGKFVKVERQVHDMGKKLDFLVDMHLQHMERLQVHVAGFSPS
KGASSPAEAEQKEDRRDADLKTIICNYSETGAPDAPYSFHQVPVDKVGPYGFFAHDPVNL
PLGGPSSGKGHATPYAERPTVLPILTLLDSRGSYRSQVELHGPCSDRVSPRQRRSITRDS
DTPLSLMSVNHEELERSPSGFSISQDRDDYAFGPSGGSSWMREKRYLAEGETDTDTEPFT
PSGSLPLSSTGDGISDSIWTPSGKPT

>Myotis lucifugus_KCNQ3
QTPSSFPPRFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFVFGAEFALRIWAAGC
CCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLRM
DRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEF
ETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQ
EQHRQKHFEKRRKPAAELIQAAWRYYATNPNRIDLVATWRFYESVVSFPFFRKEQLEAAA
SQKLGLLDRVRLSNPRGSNTKGKLFTPLNVDAIEESPSKEPKPVGLNNKERFRTAFRMKA
YAFWQSSEDAGTGDPMAEDRDYGNDFIEDMIPTLKAVIRAVRILQFRLYKKKFKETLRPY
DVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGAAFTYPSQQSPRN
EPYLARASTSEMEDQSMMGKFVKVERQVQDMGRKLDFLVDMHMQHMERLQAHVPYYDPAK
GTSPAAEEERGDPRDSEMKTILCNYSETGLPDPSFSFHQVPIDKVSPYRFFAHDPVGLPR
GGPGSGRVPGTLSSSTPAYMERPTVLPILTLLPSPTDPHGLRQRRSFTRDSDTPLSLMSV
DHEELERSPSGFSISQDRDDVFGLGGGSSWMREKRYLAEGETDTDTDPFTPSSSMPLSST
GDGISDSIWTPSNKPV

>Monodelphis domestica_KCNQ3
FLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRG
RLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLRMDRRGGTWKL
LGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEIDAQGVEMKEEFETYADALWW
GLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFE
KRRKPAAELIQAAWRYYATNPNRIDLVATWRFYESIVSFPYFRQQLEAAASQKLGLLDRV
RLSNPRGTNTKGKLFTPLNVDAIEESPSKEPKNVGLNNKERFRTAFRMKAYAFWQSSEDA
GTGEPMAEERGYSNEFLIEDMIPTLKSAIRAVRPAVFALFCTVTGLASTKYSEILFSYFF
RSFRVDMIFTPGPPSTPKHKKSQRGGAFTYPSQQSPRNDPYVAKASSSEIEDQSMMGKFV
KVERQVHDMGKKLDFLVDMHMQHMEQLQVQVTEYYPTKKATATPAEAEKKEENKYSELKT
IIYNYSEPCTQESPYSFHQVPVNKVSPYAFFAHDPEKLPRTVPSSVPYAERPTVLPILTL
LDSRVSYHSQAELHSPYQDRISPRQRRSFTRDSDTPLSLLSVNHEELERSPSGFSISQDR
DDYLFGPNGGSSWMREKRYLAEGETDTDTDPFTPSGSMPLSSTGDGISDSIWTPSNKPV

>Gallus gallus_KCNQ3
MGLKARRGAAGGSGAGGAAEGRRAAGGGGGDPEQGSLALGSGADRDGTLLLEGGGKEEGG
KRSPPGLGLLAKTPLSRPVKRNHAKYRRIQTLIYDALERPRGWALLYHGFVFLIVLGCLI
LAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPL
CMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLRMDRRGGTWKLLGSAICAHS
KELITAWYIGFLTLILSSFLVYLVEKDVPEKDANGVEMKEEFETYADALWWGLITLATIG
YGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAEL
IQAAWRYYATNPNRIDLVATWRFYESIVSFPFFRKEQLDGTASQKLGLLDRVRGTNTKGK
LFTPLNVDAIEESPSKEPKNVVLNNKERFRTAFRMKAYAFWQSSEDAGTGEPGGEERGDS
SDFLMEDMIPTFKTAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKY
LQARVDMIFTPGPPSTPKHKKSQKGGAFSYPSQQSPRNDPYVAKASTVDTEDQSMMGKFV
KVERQVNDMGKKLDFLVDMHMHHMEQLQIQVAEISPLKETASPAKEKREENKYSELKTII
YKYTDQCTHETPYNFQQVPVNKVSPYGFSAHGHMTHSQPLSTGGQNSGKLQATPSSASYA
ERPTVLPIFTLMDSQVSYHSQGDMQSPYSDKVSPRQRRSLTRDSDTPLSLLSVNHEELER
SPSGFSISQDRDDFPFGPNGGCAWMREKRYLAEGETDTDTDPFTPSGSMPLSSTGDGISD
SIWTPSNKPV     

>Anolis carolinensis_KCNQ3
MGLKARKAAAAGAKAAPSSSLAAPPPRPRGPGAEPGEGPKGADLEQGGGGGAGADKDGTL
LLGRPTREEEDDDEEEGLPQRRSAGQGLGLLAKTPLSRHPVKRHNLKYRRSQTLIYDALE
RPRGWALLYHAFVFLIVLGCLILAVLTTFKDYEKASEKWLLLLETFAIFIFGAEFALRIW
AAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILR
MLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVAETNEQGQET
RDFETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLVGVSFFALPAGILGSGLAL
KVQEQHRQKHFEKRRKPAAELIQAAWRYYATNPNRLDLVATWRFYESVVSFPYFRKEQVD
GTSQKLGLLDRVRGTNTKGKLFTPLNVDAIEESPSKEPKSVVVLNNRERFRTAFRMKAYA
FWQSSEDAGTGDPLAEDRGYSNELITEDMIPTLKAVIRAVRILQFRLYKKRFKETLRPYD
VKDVIEQYSAGHLDMLSRIKYLQTRIDMIFAPGPPSTPKHKKSQKGGTFSYPSQQSPRNE
PYIAKASTVDSEDQSMMGKFVRVERQVHDMGKKLDFLVDMHMQHMEQLQVQVTEVCPSKE
ASSPAEDNRYSELKSIIYKYSEPSIHEKPPSFHHVPVNKVPPFGFTTQGQSCGPFPSPFG
GQNSSRWPAMPFSTSYAERPTVLPILTFIDPHISYQSPPGDFQSPHSERIPSRQKHSVTR
DSDTPLSLLSVNHEELERSPSGFSISQDRDDFLFGPNGGSSWMKEKRYLAEGETDTDTDP
FTPSGSMPLSSTGDGLSDSIWTPSSKPV

>Xenopus tropicalis_KCNQ3
WAANWATLMFLIVLGCLILAILTTFKEYEDASGDWLLLLETFALVIFGVEFALRIWAAGC
CCRYKGWRGRLKFARKPLCMLDIYIYIPAFSLLTIGHNNQICCRLVNSLQWVASHLKGTM
SYSTWENLNLHYMAANRELITAWYIGFLTLILSSFLVYLVEKDVPERNEKGELVEEEFET
YADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQ
HRQKHFEKRRKPAAELIQSAWRFYATNLSRIDLIATWRYYETTVQFPYFRLRKEQMDGTN
RLVIHFGLFVERIGSEKGLYGKYILFLPLGVTVAAPMNSKGDRGPGLHHCNKFHNDFQAK
IQSLWSKNDAGAAGEPIAESGYGAEAMLEDLIPTIKAAIHASRILQFLLHKKRFKETLRP
YDVKDVIEQYSAGHLDMLSRIKYLQTRIDMVFAPGPLSTPKHKKSQKGTGGLGGGFGYSS
QQSPRHDPYSVKVPEIEDQSMMGKFVKVERQVQDMEKKLDFLVDMHMQHMDQLQVHITEY
YPLRETLAEDEGVDSRYSEVEGLIYNYTESCAHTSPYHHLHQVSFNKTNQYGFFENYPRN
FSAPLPFNGENCPRVATPPSSSYTERPTVLPIQTLIDTRVEFQDSGGASNPYLKEASPTQ
RRSFRDSDTPLSLLSVNHDELQRSPSGFSISQEKEDFSFGNNGSNWMREKRFLAEGETDT
DTDPFTPSGPITLSSTGDGISESAWTPSKPV

>Tetraodon nigroviridis_KCNQ3
GFSLVFHVFRFLIVLGCLILAVLTTFKEHEKVSAHWLVILETFAIFIFGAEFALRIWAAG
CRCRYKGWRGRLQFARKAALRAGDIFVLIASVPVVAVRNQGNVLATLRSLRFLQILRMLR
MDRRGGTWKLLGSAIYAHSKELITAWYIGFLSLILASFLVYLVEKDDVSVDASDPESPTA
QPRTQDFDTYADALWWGAGRSDGPHSCEQRTVGALVGDRRNLPHADGSSWNQTNNLSGLI
RNLLCCPSSQKLRLLERVRLPNAPTGSSDGAEESPSKPAGFSNRERLRTAFRMRAYTLRQ
SSEDPAAPTEAAVEERGFPPDILLEEMIPTLKLVIRAVRILQFLLNKKRFKETLRPYDVK
DVIEQYSAGHLDMLCRIKYLQTRIDMILAPGPPLTPKQKKSQKPPFACPSSQSPRHESFL
PKAASLPDAEDQSMMGRFVRVERQVEDMEKKLDFLVDMHIQHTEHLQVDSVGTAHMTLEA
CHPTGNGEIRRVFLNYAEGFPHMAYQVPVGGASRTREGQRLPAAVPTYTERPTVLPISSL
QDQAGGVARTTGGRGADTPLSMLSVNHEELERSPSGFSISGERDGEDGGGPSAGATVRTR
ARPTHLAEGETDTDTDPFTPSGGPLPLSSTGEGFGESVWATPP

>Gasterosteus aculeatus_KCNQ3
ASGSEEQKQTCGAPPGDLDQGTGGADRDGALLLAAPGREDFKRGSQGIGIGLLAKTPLNY
TGPAKRNNNRRRRIQNLLYDALERPRGWALLYHAFVFLIVLGCLILAILTTFREHEKVSA
HWLVILETFAIFIFGAEFGLRVWAAGCCCRYKGWRGEAQVRKLLCILGKHVSNVGIGSSL
KEHSRVNAACRGGTQVTEVTEVTVSHLQITLTTIGYGDKTPKTWAGRLLAGTFALIGVSF
FALPAGILGSGLALKVQEQHRQKHFEKRRHPAAGLIQSAWRYYSTNPIREDLIATWRFYE
TIISLPCFRKDHLEAIASQKLSLLERVRLPNARPSIGTGKRLTGHTDSIEESPSKEPKPA
GFSNRERFRTAFRMKAYTLRQSSEDGGALAEPALEERGFPPDILMEEMIPTLKLVIRAVR
IMQFLLNKKRFKETLRPYDVKDVIEQYSAGHLDMLCRIKYLQTRIDMILAPGPLLTPKQK
KTPKAPFNYPANQSPRHESYLAKATSIPDVEDLSMMGRFVRVERQVEDMEKKLDFLVDMH
IQHSEHLQVDSAGAAHMTLEACNPTGAGEIRRVFFNYAESFPHLSYQMPVGKMSGGSGGG
GGHQPPPPLLHQRRPPAAVPTYAERPTVLPISSLQDLSAGPGRTTGARGGDSPLSMLSVH
DELERSSGFSISGSRMKPAGRDPDPSYLAEGETDTDTDPFTPSGGALPLSSPGEGFGDAV
WNTPP

>Oryzias latipes_KCNQ3
FLIVLGCLILAILTTFKEHENTSAHWLVILETFAIFIFGAEFGLRIWAAGCCCRYKGWRG
RLKFARKPLCILDIFVLIASVPVVVVRNQGNVLATSLRSLRFLQILRMLRMDRRGGTWKL
LGSAIYAHSKELITAWYIGFLSLILASFLVYLVEKDDVSVDGSDREDPTVQPKQQDFDTY
ADALWWGLITLTTIGYGDKTPKTWAGRLLAGTFALIGVSFFALPAGILGSGLALKVQEQH
RQKHFEKRRHPAAGLIQSAWRYYSTNPVRDDLIATWRFYETIISLPCFRQDTFEVMVSQK
LSLLERVRLSNTRPSVGMGKRLMGNADSVEDSPSKESKPAGFSNRERFRTAFRMKAYTLR
QSSEDAGALADPALEERGFPPDILMEDMIPTLKLVIRATRIMQFLLNKKRFKETLRPYDV
KDVIEQYSAGHLDMLCRIKYLQTRIDMILAPGPLLTPKSKKTQKTPFSYPANQSPRQESY
LPKTTAMPDTDDQSMMGRFVRVERQVEDMEKKLDFLVDMHIQHTEHLQVDSAGTAHMTLE
TCGPGANGEIRRVFLNYSEAFPHMSYQVAIGKAGRGRGDQECRRGAGLARGHPERPAMGT
VPTYIERPTVLPISSLQDLSAGPGRTTGRQGGDSPLSMLSVNHEELERSPSGFSISVDRE
GDERVPTEADMATGEVSWTRPRPSYLAEGETDTDTDPFTPSGGALPLSSTGEGFCDAEWN
APLsubfamily Q-KCNQ
>Homo sapiens_KCNQ4(ENSP_262916)
MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPG
PGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLST
IQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFI
VFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELIT
AWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLA
AGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRA
YLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHR
PGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQ
KSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRIL
KFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKG
DKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLF
DPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD
>Pan troglodytes_KCNQ4(ENSPTRP_1033)
MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPG
PGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLST
IQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFI
VFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELIT
AWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLA
AGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRA
YLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHR
PGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQ
KSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSVRIL
KFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKG
DKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLF
DPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD
>Gorilla gorilla_KCNQ4(ENSGGOP_21390)
FLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQG
RFRFARKPFCVIGNEXEELRKKSELGLREMGDLYPFPVWKSPTSPRQAQRSELITAWYIG
FLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFAL
LGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTAT
WYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTS
FCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSF
NDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDVMPAVKTVIRSVRILKFLVA
KRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPS
DAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLFDPDIT
SDYHSPVDHEDISVSAQTLSISRSVSTNMD
>Mus musculus_KCNQ4(ENSMUSP_30376)
MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPG
PGSGSGSACGGQRSSAAQKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLS
TIQEHQELANECLLILEFVMIVVFGLEYIIRVWSAGCCCRYRGWQGRFRFARKPFCVIDF
IVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELI
TAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVL
AAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDTSR
AYLTATWYYYDSILPSFRELALLFEHIQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCH
RPGSASFCPGESSRMGIKDRIRISSSQKRTGPSKQHLAPPPIPTSPSSEQVGEASSPSKV
QKSWSFNDRTRFRASLRLKPRCSAEEGPSEEVAEEKSYQCELTVDDVMPAVKTVIRSVRI
LKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQARVDQIVGRGPGDRKTREK
GDKGPSDTEAVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGTVQVPL
FDPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD
>Dasypus novemcinctus_KCNQ4(ENSDNOP_17886)
MAEAPPRRLGLAPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRHGLLGSPLPPGAPLPG
PGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLST
IQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFI
VFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELIT
AWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLA
AGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDTSRA
YLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRVPVPDGAPSRYPPVATCHR
PGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPPIPTSPSSEQMGEATSPTKVQ
KSWSFNDRTRFRASLRLKPRTSAEEGPSEDVAEEKSYQCELTVDDVMPAVKTVIRSVRIL
KFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQARVDQIVGRGTGDRKAREKG
DKGPSDPEAVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGTVQVPLF
DPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD
>Xenopus tropicalis_KCNQ4(ENSXETP_49800)
MAVGTQPQADNGRVPSLSLAPISGQESGMEFVALTAVQTDSGNPRRLGLLGTPIPGAPRS
SSSHKKYRRLQNYLYNVLERPRGWAFIYHAFIFFLVFSCLVLSVFSTIPEYHHLANKGLF
ILEFVMIVVFGMEYVIRIWSAGCCCRYRGWKGRLRFARKPFCVIDFIVLVASLAVIAAGT
QGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFAS
FLVYLAEKDANKEFSTYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFAL
PAGILGSGFALKVQEQHRQKHFEKRRTPAANLIQAAWRLYSTDVSRSYLTATWYYYDSIL
PSFRELLLLFDTWHRTCSRNGGVRLCQGSPRYQPVPSTPKPATPPFCTGESSKLGLKDRM
RGTVAPKQTTRSKQYLAPPERASPGTEPAAETPSPTKVQKSWSFNDRTRFRASLRLKSRP
QADEGPGDDINDEKRLPNDLTMEDVMPTIKTLIRAFRILKFLVAKRKFKETLRPYDVKDV
IEQYSAGHLDMLGRIKSLQGRVDQIIGRGPVPVEKKPRDKGEKVSTMGPEVEAADELSMM
GRVVKVERQVQSIEDKLDILLGFYSQCIRKGPASSFTLTSMQMPLIDQEMTSDYQSPVDP
VDFSVSAQTLNISHSASTNME
>Takifugu rubripes_KCNQ4(ENSTRUP_36608)
MLGSPSNNGGIRMLAPPAPDDDRRVEFVALTAVHTERSEPSTPERGHPSHRTGLLGTPLP
GPPGPRANTSASSKRFRKLQNFLYNVLERPRGFAFIYHAFNFLLVFSCLVLSVFSTIHEH
QKFANQDSSSWWLLHEFVMIVVFGLEYFIRIWAAGCCCRYRGWQGRLRFARKPFCVIDLI
VFVPSLAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELIT
AWYIGFLVLIFASFFVYLVEKDVNTDFNTYADSLWWGTITLTTIGYGDKTPRTWQGRLLA
AGFALLGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDASHS
YLTATWYFYDSMLPSFRELTLLFSHLQRQRNKQLLPLHDTYAQIHAGRKQRYPRLRACAR
GSADCFVPSRGEGSKIGFRDRIRMNNSRSSQTIRSKASPLPPGSNVRRSPSQENVPDPTS
PGKVQKSWSFNDRTRFRTSLRLKPRPPADVEGVGEDSTEDKPYCDMAMEEVIPAVKTLIR
AVRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIIGRGAVQPD
KKARPEKGEKTPPELDSLDELSMMGRVVKVEKQVQSIENKLDLLLNLYSHCLKKGSSNYT
LSTLLDPDLTSDYHSPTDQRDLFPSANTLNISTSESGNLE
>Tetraodon nigroviridis_KCNQ4(ENSTNIP_5762)
MLGSPSNNGGIRMLAPPAPDDERRVEFVALTAVHTERSEPSTPERGHPSHRTGLLGTPLP
GPPGPRASASASSKRFRKLQNFLYNVLERPRGFAFIYHAFIFLLVFSCLVLSVFSTIPEH
QKFANQGLFILEFVMIVVFGLEYFIRIWAAGCCCRYRGWQGRLRFARKPFCVIDLIVFVA
SLAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYI
GFLVLIFASFLVYLAEKDINTDFSTYADSLWWGTITLTTIGYGDKTPRTWQGRLLAAGFA
LLGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDASHSYLTA
TWYFYDSMLPSFRELTLLFSHLQRRTPGALWSIETSHLTPPPCSQERVPDLKPCPPRFHS
FFFAVSSKIGFRDRIRMNNSRSSQTIRSKASPLPPGSNGRRSPSQENMADSTSPGKVQKS
WSFNDRTRFRTSLRLKPRPPADAEGVGEDSVEDKPYCDVAMEEVIPAVKTLIRAVRILKF
LVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIIGRGAVQPDKKVRPEK
GEKTPPELDSLDELSMMGRVVKVEKQQVQSIENKLDLLLDLYSHCLKKGSSNFTLSTLLD
PDLTSDYHSPTDQRDLFPSANTLNISTSESGNLE
>Gasterosteus aculeatus_KCNQ4(ENSGACP_6436)
MPESPSNNGGARMLAPPTSSDDRRVEFVALTAVHTERSEPSSPERGHPSNRTGLLGTPHT
SASNKRYRKLQNCLYNVLERPRGWAFIYHAFIFLLVFSCLVLSVFSTIPDHQRFANQGLF
ILEFVMIVVFGLEYFIRIWAAGCCCRYRGWQGRLRFARKPFCVIDFIVFVASLAVIAAGT
QGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFAS
FLVYLAEKDINSDFNTYADSLWWGTITLTTIGYGDKTPRTWQGRLLAAGFALLGVSFFCP
CLLTPQGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDAKHSYLTATWYFY
DSMLPSFSARGGVRELTLLFSHLQRQRNTKKVLPSSYHTLLSGLRPYSLPYLSGDSSKMG
FRDRIRMNNSRSSQTIRSKGSPLPPSSGVRGSPSQENVPEAISPGKVQKSWSFNDRTRFR
TSLRLKTRPPVDGSVEGVGEDSVEDKPYCDVSMEEVIPAVKTLIRAVRILKFLVAKRKFK
ETLRPYDVKDVIEQYSAGHLDMLGRIKSLQMRVDQIIGRGAVQPDKKARTEKGEKTPPEL
DPLDELSMMGRVVKVEKQVQSIENKLDLLLSFYSQCLKKGSSHFTLSSLLDPELTSDYHS
PTDQRDLFPSANTLNISESGNLE
>Oryzias latipes_KCNQ4(ENSORLP_15074)
PGPNDDRRVEFVALTAVQTERSEPSTPERGPPSHRTGLLGTPLPGPPGPRASASASSKRF
RKLQNFLYNVLERPRGWAFIYHAFMWEVRMSSVLFLCALQEFVMIVVFGMEYFIRIWAAG
CCCRYRGWQGRLRFARKPFCVIDFIVFVASLAVIAAGTQGNIFATSALRSMRFLQILRMV
RMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDINSDFGTYADSLW
WGTITLTTIGYGDKTPRTWQGRLLAAGFALLGVSFFALPAGILGSGFALKVQEQHRQKHF
EKRRMPAANLIQAAWRLYSTDAKHSYLTATWYFYDSMLPSFRELTLLFSHLQRQRSTKKV
LQNSYHTLLSGLRPNSSPYLSGDSSKMGFRDRIRMNNSRSSQAIRNKASPLPPGSGVRRS
PSQENIPEATSPGKVQKSWSFNDRTRFRTSLRLKPRPPVDAEGLGEDSVEDKPYCDVAMD
EVIPAVKTLIRAVRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQMRVD
LIIGRGPVQPDKKTRPEKGEKTPPDLDPLDELSMMGRVVKVEKQVQSIEGKLDLLLSFYS
QCIKKGSSHVTLSSLLDPDLTSDYHSPTDHRDLFPSANTLNISRSESDNLE
>Homo sapiens_KCNQ3(ENSP_373648)
MGLKARRAAGAAGGGGDGGGGGGGAANPAGGDAAAAGDEERKVGLAPGDVEQVTLALGAG
ADKDGTLLLEGGGRDEGQRRTPQGIGLLAKTPLSRPVKRNNAKYRRIQTLIYDALERPRG
WALLYHALVFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGC
CCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLRM
DRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEF
ETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQ
EQHRQKHFEKRRKPAAELIQAAWRYYATNPNRIDLVATWRFYESVVSFPFFRKEQLEAAS
SQKLGLLDRVRLSNPRGSNTKGKLFTPLNVDAIEESPSKEPKPVGLNNKERFRTAFRMKA
YAFWQSSEDAGTGDPMAEDRGYGNDFPIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRP
YDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTFPSQQSPR
NEPYVARPSTSEIEDQSMMGKFVKVERQVQDMGKKLDFLVDMHMQHMERLQVQVTEYYPT
KGTSSPAEAEKKEDNRYSDLKTIICNYSETGPPEPPYSFHQVTIDKVSPYGFFAHDPVNL
PRGGPSSGKVQATPPSSATTYVERPTVLPILTLLDSRVSCHSQADLQGPYSDRISPRQRR
SITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFGPNGGSSWMREKRYLAEGETDT
DTDPFTPSGSMPLSSTGDGISDSVWTPSNKPI
>Macaca mulatta_KCNQ3(ENSMMUP_11684)
XGDAAAAGDEERKVGLAPGDVEQVTLALGAGADKDGTLLLEGGGRDEGQRRTPQGIGLLA
KTPLTRPVKRNNAKYRRIQTLIYDALERPRGWALLYHALVFLIVLGCLILAVLTTFKEYE
TVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIAS
VPVVAVGNQGNVLATSLRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGF
LTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPKTWEG
RLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWRYYATN
PNRIDLVATWRFYESVVSFPFFRQLEAASSQKLGLLDRVRLSNPRGSNTKGKLFTPLNVD
AIEESPSKEPKPVGLNNKERFRTAFRMKAYAFWQSSEDAGTGDPTAEDRGYGNDFPIEDM
IPTLKAAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMI
FTPGPPSTPKHKKSQKGSAFTFPSQQSPRNEPYVARPSTSEIEDQSMMGKFVKVERQVQD
MGKKLDFLVDMHMQHMERLQVQVTEYYPTKGTSSPAEAEKKEDNRYSDLKTIICNYSETG
PPEPPYSFHQVPIDKVSPYGFFAHDPVNLPRGGPSTGKVQAAPPSSATTYAERPTVLPIL
TLLDSRVSCHSQADLQGPYSDRISPQQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQ
DRDDYVFGPNGGSSWMREKRYLAEGETDTDTDPFTPSGSMPLSSTGDGISDSVWTPSNKP
I
>Mus musculus_KCNQ3(ENSMUSP_63380)
MGLKARRAAGAAGGGGGEGGGGGGGAANPAGGDSAVAGDEERKVGLAPGDVEQVTLALGA
GADKDGTLLLEGGGREEGQRRTPQGIGLLAKTPLSRPVKRNNAKYRRIQTLIYDALERPR
GWALLYHALVFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAG
CCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLR
MDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEMDAQGEEMKEE
FETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKV
QEQHRQKHFEKRRKPAAELIQAAWRYYATNPNRLDLVATWRFYESVVSFPFFRKEQLEAA
ASQKLGLLDRVRLSNPRGSNTKGKLFTPLNVDAIEESPSKEPKPVGLNNKERFRTAFRMK
AYAFWQSSEDAGTGDPMAEDRGYGNDFLIEDMIPTLKAAIRAVRILQFRLYKKKFKETLR
PYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTYPSQQSP
RNEPYVARAATSETEDQSMMGKFVKVERQVHDMGKKLDFLVDMHMQHMERLQVHVTEYYP
TKGASSPAEGEKKEDNRYSDLKTIICNYSETGPPDPPYSFHQVPIDRVGPYGFFAHDPVK
LTRGGPSSTKAQANLPSSGSTYAERPTVLPILTLLDSCVSYHSQTELQGPYSDHISPRQR
RSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFGPSGGSSWMREKRYLAEGETD
TDTDPFTPSGSMPMSSTGDGISDSIWTPSNKPT
>Bos taurus_KCNQ3(ENSBTAP_27546)
MGLKARRPAGAAGGGGDGGGGGGGAANPAGGDAAAAGDEERKVGLAPGDVEQVTLALGAG
ADKDGTLLLEGGGRDEGQRRTPQGIGLLAKTPLSRPVKRNNAKYRRIQTLIYDALERPRG
WALLYHALVFLIVLGCLILAVLTTFREYETVSGDWLLLLETFAIFIFGAEFALRIWAAGC
CCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLRM
DRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEF
ETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQ
EQHRQKHFEKRRKPAAELIQAAWRYYATNPNRIDLVATWRFYESVVSFPFFRKEQLDPAA
SQKLGLLDRVRLSNPRGSNTKGKLFTPLNVDAIEESPSKEPKPVGSNNKERFRTAFRMKA
YAFWQSSEDAGTGDPTAEDRGYGNDFLIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRP
YDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQRGAAFTYPSQQSPR
NEPYVARPSTSETEDQSMMGKFVKVERQVHDMGKKLDFLVDMHLQHMERLQVHVAGFSPS
KGASSPAEAEQKEDRRDADLKTIICNYSETGAPDAPYSFHQVPVDKVGPYGFFAHDPVNL
PLGGPSSGKGHATPYAERPTVLPILTLLDSRGSYRSQVELHGPCSDRVSPRQRRSITRDS
DTPLSLMSVNHEELERSPSGFSISQDRDDYAFGPSGGSSWMREKRYLAEGETDTDTEPFT
PSGSLPLSSTGDGISDSIWTPSGKPT
>Myotis lucifugus_KCNQ3(ENSMLUP_14023)
QTPSSFPPRFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFVFGAEFALRIWAAGC
CCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLRM
DRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEF
ETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQ
EQHRQKHFEKRRKPAAELIQAAWRYYATNPNRIDLVATWRFYESVVSFPFFRKEQLEAAA
SQKLGLLDRVRLSNPRGSNTKGKLFTPLNVDAIEESPSKEPKPVGLNNKERFRTAFRMKA
YAFWQSSEDAGTGDPMAEDRDYGNDFIEDMIPTLKAVIRAVRILQFRLYKKKFKETLRPY
DVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGAAFTYPSQQSPRN
EPYLARASTSEMEDQSMMGKFVKVERQVQDMGRKLDFLVDMHMQHMERLQAHVPYYDPAK
GTSPAAEEERGDPRDSEMKTILCNYSETGLPDPSFSFHQVPIDKVSPYRFFAHDPVGLPR
GGPGSGRVPGTLSSSTPAYMERPTVLPILTLLPSPTDPHGLRQRRSFTRDSDTPLSLMSV
DHEELERSPSGFSISQDRDDVFGLGGGSSWMREKRYLAEGETDTDTDPFTPSSSMPLSST
GDGISDSIWTPSNKPV
>Monodelphis domestica_KCNQ3(ENSMODP_1454)
FLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRG
RLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLRMDRRGGTWKL
LGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEIDAQGVEMKEEFETYADALWW
GLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFE
KRRKPAAELIQAAWRYYATNPNRIDLVATWRFYESIVSFPYFRQQLEAAASQKLGLLDRV
RLSNPRGTNTKGKLFTPLNVDAIEESPSKEPKNVGLNNKERFRTAFRMKAYAFWQSSEDA
GTGEPMAEERGYSNEFLIEDMIPTLKSAIRAVRPAVFALFCTVTGLASTKYSEILFSYFF
RSFRVDMIFTPGPPSTPKHKKSQRGGAFTYPSQQSPRNDPYVAKASSSEIEDQSMMGKFV
KVERQVHDMGKKLDFLVDMHMQHMEQLQVQVTEYYPTKKATATPAEAEKKEENKYSELKT
IIYNYSEPCTQESPYSFHQVPVNKVSPYAFFAHDPEKLPRTVPSSVPYAERPTVLPILTL
LDSRVSYHSQAELHSPYQDRISPRQRRSFTRDSDTPLSLLSVNHEELERSPSGFSISQDR
DDYLFGPNGGSSWMREKRYLAEGETDTDTDPFTPSGSMPLSSTGDGISDSIWTPSNKPV
>Gallus gallus_KCNQ3(ENSGALP_56287)
MGLKARRGAAGGSGAGGAAEGRRAAGGGGGDPEQGSLALGSGADRDGTLLLEGGGKEEGG
KRSPPGLGLLAKTPLSRPVKRNHAKYRRIQTLIYDALERPRGWALLYHGFVFLIVLGCLI
LAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPL
CMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLRMDRRGGTWKLLGSAICAHS
KELITAWYIGFLTLILSSFLVYLVEKDVPEKDANGVEMKEEFETYADALWWGLITLATIG
YGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAEL
IQAAWRYYATNPNRIDLVATWRFYESIVSFPFFRKEQLDGTASQKLGLLDRVRGTNTKGK
LFTPLNVDAIEESPSKEPKNVVLNNKERFRTAFRMKAYAFWQSSEDAGTGEPGGEERGDS
SDFLMEDMIPTFKTAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKY
LQARVDMIFTPGPPSTPKHKKSQKGGAFSYPSQQSPRNDPYVAKASTVDTEDQSMMGKFV
KVERQVNDMGKKLDFLVDMHMHHMEQLQIQVAEISPLKETASPAKEKREENKYSELKTII
YKYTDQCTHETPYNFQQVPVNKVSPYGFSAHGHMTHSQPLSTGGQNSGKLQATPSSASYA
ERPTVLPIFTLMDSQVSYHSQGDMQSPYSDKVSPRQRRSLTRDSDTPLSLLSVNHEELER
SPSGFSISQDRDDFPFGPNGGCAWMREKRYLAEGETDTDTDPFTPSGSMPLSSTGDGISD
SIWTPSNKPV
>Anolis carolinensis_KCNQ3(ENSACAP_10760)
MGLKARKAAAAGAKAAPSSSLAAPPPRPRGPGAEPGEGPKGADLEQGGGGGAGADKDGTL
LLGRPTREEEDDDEEEGLPQRRSAGQGLGLLAKTPLSRHPVKRHNLKYRRSQTLIYDALE
RPRGWALLYHAFVFLIVLGCLILAVLTTFKDYEKASEKWLLLLETFAIFIFGAEFALRIW
AAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILR
MLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVAETNEQGQET
RDFETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLVGVSFFALPAGILGSGLAL
KVQEQHRQKHFEKRRKPAAELIQAAWRYYATNPNRLDLVATWRFYESVVSFPYFRKEQVD
GTSQKLGLLDRVRGTNTKGKLFTPLNVDAIEESPSKEPKSVVVLNNRERFRTAFRMKAYA
FWQSSEDAGTGDPLAEDRGYSNELITEDMIPTLKAVIRAVRILQFRLYKKRFKETLRPYD
VKDVIEQYSAGHLDMLSRIKYLQTRIDMIFAPGPPSTPKHKKSQKGGTFSYPSQQSPRNE
PYIAKASTVDSEDQSMMGKFVRVERQVHDMGKKLDFLVDMHMQHMEQLQVQVTEVCPSKE
ASSPAEDNRYSELKSIIYKYSEPSIHEKPPSFHHVPVNKVPPFGFTTQGQSCGPFPSPFG
GQNSSRWPAMPFSTSYAERPTVLPILTFIDPHISYQSPPGDFQSPHSERIPSRQKHSVTR
DSDTPLSLLSVNHEELERSPSGFSISQDRDDFLFGPNGGSSWMKEKRYLAEGETDTDTDP
FTPSGSMPLSSTGDGLSDSIWTPSSKPV
>Xenopus tropicalis_KCNQ3(ENSXETP_49802)
WAANWATLMFLIVLGCLILAILTTFKEYEDASGDWLLLLETFALVIFGVEFALRIWAAGC
CCRYKGWRGRLKFARKPLCMLDIYIYIPAFSLLTIGHNNQICCRLVNSLQWVASHLKGTM
SYSTWENLNLHYMAANRELITAWYIGFLTLILSSFLVYLVEKDVPERNEKGELVEEEFET
YADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQ
HRQKHFEKRRKPAAELIQSAWRFYATNLSRIDLIATWRYYETTVQFPYFRLRKEQMDGTN
RLVIHFGLFVERIGSEKGLYGKYILFLPLGVTVAAPMNSKGDRGPGLHHCNKFHNDFQAK
IQSLWSKNDAGAAGEPIAESGYGAEAMLEDLIPTIKAAIHASRILQFLLHKKRFKETLRP
YDVKDVIEQYSAGHLDMLSRIKYLQTRIDMVFAPGPLSTPKHKKSQKGTGGLGGGFGYSS
QQSPRHDPYSVKVPEIEDQSMMGKFVKVERQVQDMEKKLDFLVDMHMQHMDQLQVHITEY
YPLRETLAEDEGVDSRYSEVEGLIYNYTESCAHTSPYHHLHQVSFNKTNQYGFFENYPRN
FSAPLPFNGENCPRVATPPSSSYTERPTVLPIQTLIDTRVEFQDSGGASNPYLKEASPTQ
RRSFRDSDTPLSLLSVNHDELQRSPSGFSISQEKEDFSFGNNGSNWMREKRFLAEGETDT
DTDPFTPSGPITLSSTGDGISESAWTPSKPV
>Tetraodon nigroviridis_KCNQ3(ENSTNIP_8726)
GFSLVFHVFRFLIVLGCLILAVLTTFKEHEKVSAHWLVILETFAIFIFGAEFALRIWAAG
CRCRYKGWRGRLQFARKAALRAGDIFVLIASVPVVAVRNQGNVLATLRSLRFLQILRMLR
MDRRGGTWKLLGSAIYAHSKELITAWYIGFLSLILASFLVYLVEKDDVSVDASDPESPTA
QPRTQDFDTYADALWWGAGRSDGPHSCEQRTVGALVGDRRNLPHADGSSWNQTNNLSGLI
RNLLCCPSSQKLRLLERVRLPNAPTGSSDGAEESPSKPAGFSNRERLRTAFRMRAYTLRQ
SSEDPAAPTEAAVEERGFPPDILLEEMIPTLKLVIRAVRILQFLLNKKRFKETLRPYDVK
DVIEQYSAGHLDMLCRIKYLQTRIDMILAPGPPLTPKQKKSQKPPFACPSSQSPRHESFL
PKAASLPDAEDQSMMGRFVRVERQVEDMEKKLDFLVDMHIQHTEHLQVDSVGTAHMTLEA
CHPTGNGEIRRVFLNYAEGFPHMAYQVPVGGASRTREGQRLPAAVPTYTERPTVLPISSL
QDQAGGVARTTGGRGADTPLSMLSVNHEELERSPSGFSISGERDGEDGGGPSAGATVRTR
ARPTHLAEGETDTDTDPFTPSGGPLPLSSTGEGFGESVWATPP
>Gasterosteus aculeatus_KCNQ3(ENSGACP_20863)
ASGSEEQKQTCGAPPGDLDQGTGGADRDGALLLAAPGREDFKRGSQGIGIGLLAKTPLNY
TGPAKRNNNRRRRIQNLLYDALERPRGWALLYHAFVFLIVLGCLILAILTTFREHEKVSA
HWLVILETFAIFIFGAEFGLRVWAAGCCCRYKGWRGEAQVRKLLCILGKHVSNVGIGSSL
KEHSRVNAACRGGTQVTEVTEVTVSHLQITLTTIGYGDKTPKTWAGRLLAGTFALIGVSF
FALPAGILGSGLALKVQEQHRQKHFEKRRHPAAGLIQSAWRYYSTNPIREDLIATWRFYE
TIISLPCFRKDHLEAIASQKLSLLERVRLPNARPSIGTGKRLTGHTDSIEESPSKEPKPA
GFSNRERFRTAFRMKAYTLRQSSEDGGALAEPALEERGFPPDILMEEMIPTLKLVIRAVR
IMQFLLNKKRFKETLRPYDVKDVIEQYSAGHLDMLCRIKYLQTRIDMILAPGPLLTPKQK
KTPKAPFNYPANQSPRHESYLAKATSIPDVEDLSMMGRFVRVERQVEDMEKKLDFLVDMH
IQHSEHLQVDSAGAAHMTLEACNPTGAGEIRRVFFNYAESFPHLSYQMPVGKMSGGSGGG
GGHQPPPPLLHQRRPPAAVPTYAERPTVLPISSLQDLSAGPGRTTGARGGDSPLSMLSVH
DELERSSGFSISGSRMKPAGRDPDPSYLAEGETDTDTDPFTPSGGALPLSSPGEGFGDAV
WNTPP
>Oryzias latipes_KCNQ3(ENSORLP_8236)
FLIVLGCLILAILTTFKEHENTSAHWLVILETFAIFIFGAEFGLRIWAAGCCCRYKGWRG
RLKFARKPLCILDIFVLIASVPVVVVRNQGNVLATSLRSLRFLQILRMLRMDRRGGTWKL
LGSAIYAHSKELITAWYIGFLSLILASFLVYLVEKDDVSVDGSDREDPTVQPKQQDFDTY
ADALWWGLITLTTIGYGDKTPKTWAGRLLAGTFALIGVSFFALPAGILGSGLALKVQEQH
RQKHFEKRRHPAAGLIQSAWRYYSTNPVRDDLIATWRFYETIISLPCFRQDTFEVMVSQK
LSLLERVRLSNTRPSVGMGKRLMGNADSVEDSPSKESKPAGFSNRERFRTAFRMKAYTLR
QSSEDAGALADPALEERGFPPDILMEDMIPTLKLVIRATRIMQFLLNKKRFKETLRPYDV
KDVIEQYSAGHLDMLCRIKYLQTRIDMILAPGPLLTPKSKKTQKTPFSYPANQSPRQESY
LPKTTAMPDTDDQSMMGRFVRVERQVEDMEKKLDFLVDMHIQHTEHLQVDSAGTAHMTLE
TCGPGANGEIRRVFLNYSEAFPHMSYQVAIGKAGRGRGDQECRRGAGLARGHPERPAMGT
VPTYIERPTVLPISSLQDLSAGPGRTTGRQGGDSPLSMLSVNHEELERSPSGFSISVDRE
GDERVPTEADMATGEVSWTRPRPSYLAEGETDTDTDPFTPSGGALPLSSTGEGFCDAEWN
APL
>Homo sapiens_KCNQ2(ENSP_486706)
MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG
GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK
SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI
AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF
LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI
GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW
QYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSQKVS
LKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRI
KGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKES
LRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPS
MMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSRE
HVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQGHGTSPVGDHGS
LVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEEL
ERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATG
EGPFGDVGWAGPRK
>Pan troglodytes_KCNQ2(ENSPTRP_23658)
MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG
GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSWLEIVTIVVFGVEYF
VRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRF
LQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFD
TYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQE
QHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGAS
RLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSKGSPCRGPLCGCCPGRSSQKVSLKDR
VFSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAA
SRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVVDQIVGRGPAITDKDRTKG
PAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPA
PPYHSPEDSREHVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQG
HGTSPVGDHGSLVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGTLRDSDTS
ISIPSVDHEELERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCT
PCGPPPRSATGEGPFGDVGWAGPRK
>Mus musculus_KCNQ2(ENSMUSP_99340)
MVQKSRNGGVYPGTSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSVLSKPRTG
GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK
SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI
AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF
LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI
GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW
QYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLTFRKEPQPEPSPSQKVS
LKDRVFSSPRGMAAKGKGSPQAQTVRRSPSADQSLDDSPSKVPKSWSFGDRSRTRQAFRI
KGAASRQNSEEASLPGEDIVEDNKSCNCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKE
SLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPTITDKDRTKGPAETELPEDP
SMMGRLGKVEKQVLSMEKKLDFLVSIYTQRMGIPPAETEAYFGAKEPEPAPPYHSPEDSR
DHADKHGCIIKIVRSTSSTGQRNYAAPPAIPPAQCPPSTSWQQSHQRHGTSPVGDHGSLV
RIPPPPAHERSLSAYGGGNRASTEFLRLEGTPACRPSEAALRDSDTSISIPSVDHEELER
SFSGFSISQSKENLDALGSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATGEG
PFGDVAWAGPRK
>Rattus norvegicus_KCNQ2(ENSRNOP_40830)
MVQKSRNGGVYPGTSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSVLSKPRTG
GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK
SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI
AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF
LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI
GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW
QYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLTFRKEPQPEPSPSQKVS
LKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLDDSPSKVPKSWSFGDRSRARQAFRI
KGAASRQNSEEASLPGEDIVEDNKSCNCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKE
SLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPTITDKDRTKGPAETELPEDP
SMMGRLGKVEKQVLSMEKKLDFLVSIYTQRMGIPPAETEAYFGAKEPEPAPPYHSPEDSR
DHADKHGCIIKIVRSTSSTGQRNYAAPPVMPPAQCPPSTSWQQSHQRHGTSPVGDHGSLV
RIPPPPAHERSLSAYSGGNRASTEFLRLEGTPACRPSEAALRDSDTSISIPSVDHEELER
SFSGFSISQSKENLDALASCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATGEG
PFGDVAWAGPRK
>Gallus gallus_KCNQ2(ENSGALP_9339)
MVQKSRNGGVYPGPAAEKKLKVGFVGLDPGAPDSSRDGALLIAGSESTKRGSILSKPRSG
VSGSGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIDEYQN
SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI
AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELITAWYIGF
LCLILASFLVYLAEKGENEHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI
GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQAAWRFYATNLSRTDLHSTW
QYYERTVTVPMYSTQTQTYGASRLIPPLNQLELLRNLKSKSGLTFRKEQQPEPSPSQKVS
LKDRVFSSPRGAGTKGKGSPQAQGIRRSPSADQSIEDSPSKVPKSWSFGDRSRARQAFRI
KGAASRQNSEEASLPGEDIPDENKSCNCEFVTEDLTPGLKVSIRAVCIMRFLVSKRKFKE
SLRPYDVMDVIEQYSAGHLDMLSRIKNLQSRVDQIVGRGSSMTNKDRTKGPAEGELPEDP
SMMGRLGKVEKQVQSMEKKLDFLVNIYMQRMGIPPTETEAYFGSKEPDPAPPYHSPEDSR
EHIDKNGCIIKIIRSTSSMGQKNFSAPPAPTNSCPPSTSCQQQPYQRQSHGSSPVGDPGS
LVRIPPPPSHERSLSAYSGGHRASAEYLRNEDITTKHHESALRDSDTSISIPSVDHEELE
RSFSGFSISQSKENLDILNNGCYAAVAKIRPYIAEGESDTDSDLCTPCGPPPRSATGEGP
FSDMGWSAPRQ
>Anolis carolinensis_KCNQ2(ENSACAP_5855)
MSFLFLFCLFLLPSSFLLVFSCLVLSVFSTIDDYEASSEGALYILEIVTIVVFGVEYFVR
IWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQ
ILRMIRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLCLILASFLVYLAEKGENEHFDTY
ADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQH
RQKHFEKRRNPAAGLIQAAWRFYATNLSRTDLHSTWNYYERTVTVPMYSSQTQSYGASRL
IPPLNQLELLRNLKSKSGLTFRKEQQPEPSPSQKVSLKDRVFSSPRGAATKGKGSPQAPG
IRRSPSADQSIDDSPSKVPKSWSFGDRSRARQAFRIKGASSRQNSEDAGLPGEDMGDPDN
KSCNCEFVTEDLTPGLKLSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLS
RIKNLQSRIDMIVGPPPPSTPRHKKYSTKGSSPQYSPRVDQIVGRGPSMTDKDRTKGSAE
GELQEDPSMMGRLGKVEKQVQSMEKKLDFLVNIYMQRMGIPPTETEAYFGSKEPEPAPPY
HSPEDSREHIDKNGCIIKIIRSTSSMGQKNFSAPPATTVPNNSCPPSTSWQPYPRQSHGV
SPVGEPGSLVRIPPPPSHERSSSAYSGGHRASAEYAKNEDVTAKHPESALRDSDTSISIP
SVDHEELERSFSGFSISQSKENLDVLNNGCYTAVAKIRPYIAEGESDTDSDLCTPCGPPP
RSATGEGPFSDMGWSTPRQ
>Xenopus tropicalis_KCNQ2(ENSXETP_49801)
MVQKSRNGGVYPGPTGEKKLKVGFVGLDAGPPDTSRDGALLIDGSDKRSSILIKQRSGVS
GTGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVLLITWNSLNLVLFSTIKEYESSS
EGALYILEIITIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAV
LSAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLC
LILASFLVYLAEKEDNDMFDTYADALWWGLITLTTIGYGDKYPKTWNGRLLAATFTLIGV
SFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQCAWRFYATNLSRMDLHSTWQY
YERTVTVPMYSWVSSSQTYGASRLIPPLNQLDLLRNLKSKSGLTFRKEQQAEPPSSQKVS
LKERVFSSPRGVATKGKGSPQSQGMRRSPSADQSLEESPSKVPKSWSFGDRSRTRQAFRI
KGSASRQNSEVSLPEEEVAVPEENRSCNCEFLAEDLTPGLKASIRAVCIMRFLVAKRKFK
ESLRPYDVMDVIEQYSAGHLDMLARIKNLQSRVDQIVGRGGSITDKDRAKGGAETEIPDD
PSMMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPSETEAYFGAKDREPAPPYHSPEDS
RDPVDKSCITKIIRSSSSMGQKNFSAPPAQLTPTTHCPPSTSWQQQQPYHRHSHGSSPVG
DPGSLVRIPPPPSHERSLSAYGVSRMVGVEEGSGKHRDPAALRDSDTSISIPSVDHEELE
RSFSGFSISQSKENLEILNNGAVAGPGPCHKVRPYIAEGESDTDSDLCTPCGPPARSTTG
EGPYGDMGWPSSKK
>Danio rerio_KCNQ2(ENSDARP_122368)
MVKKSANGEVYLPPAGEKKPKVGFVGLDPGAAETSRDGALLIAGSESTKRGSILCRPRSS
ISRGSIAHKRNARYRRLQNFLYNALERPRGWAFIYHAYVFVLVFSCLVLSVFATIKEYKK
SSESALYILEIVTIVVFGVEYIVRIWAAGCCCRYRGWRGRLRFARKPFCIIDIMVLFASV
SVLAAGSQGNVFATSAIRSLRFLQILRMLRMDRRGGTWKLLGSVVYAHSKELITAWYIGF
LCLILASFLVYSVEKDDNAEMFETYADALWWGLVTLTTIGYGDKFPVTWNGRLIAATFSL
IGVAFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQAAWRFHATNLSRTDLFST
WDFYAQTVSVPMYSRNTLLSNLWQLIPPVNQLDILRSLKGKSAFRKDSQIDVTPSSEISH
KDTLCGCCPRTNSRKPSVKEKGSPSKSTGGKEARTDGVKESPSKVTKSLSFTDRNKAKHA
FKMKDGASRQNSEEASLPEDLGDDRGYNCEFLPHLSPGLKVTIRSICVMRFLLSKRRFKE
SLRPYDVMDVIEQYSAGHLDMLSRIKNLQIDLIVGPPPPSTPRHKKYVNIHQWPSQTRWL
YYWTALQVDQIVGKGASAGEKDKPKSDTEVPEDPSMMGRLNKMEKEVGAMDLKLNFLVSI
YTAQMGIPRSETEALLGFKIAYPAPPYHSPDEKSEKVPDEDENKGKSPSPINPGPNGTLT
ESQCRPSTSWHQQDEHPLSVPLWNNSRGVSPIGTDDPSLYRLPPPPFHESMDNSRSRRSR
RPVQQQAAVESDTSLSIPSVDHEELDRSFSGFSISQAREEDYVPPVSLGPFGGGGGTLCT
RIRPYLAEGESDTDSDLYTPGAPSPLSFTGEGTFGDRMWPGMK
>Takifugu rubripes_KCNQ2a(ENSTRUP_24561)
MVQKSLNGGVYPAEDGEKKHRVGFVGLDPGAPESSRDGALLIAGPDGAHKRSSILCRRGS
SISTGRPRPTKKNASYRKLQNFLYNALERPRGWAFVYHAYVFLLVFSCLILSVFATIKEF
KNSSESALYILEIVTIVVFGVEYIVRIWSAGCCCRYRGWRGRLKFARKPFCVIDIMVLIA
SVSVLAAGSQGNIFATSAIRSLRFLQILRMLRMDRRGGTWKLLGSVVYAHSKELITAWYI
GFLCLILASFLVYSVEKESNEEFETYADALWWGLITLTTIGYGDKVPKTWNGRMLGAAFS
MIGVAFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQGAWRFYATNLSRTDLVC
TWDFYEQTVSVPMYRIDQCQILPPPRFIPPLNQLDLLRNLKGKSFRKESQTEMSPSNENA
HKERLCGCCPRAISRKASLKDKVFPSPSKAPFAKGKAQSPGAEEGVEASPYKVAKSWSFT
DKNRGTKNSFKARGSTSRQNSEEASLPGEEMGDDKSCHCEFLTQELPSSLKVTIRAICIM
KFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLCRIKNLQTRVDQIVGKSPKADGDPGDD
LSMMGRLVKVEKQVLCMDRKLDFLVNVYVQRMGITHSETEAYFNSKEPYPAPPYHSPDDS
KLEKDNKEQMNSLEQKDPLVGRSGARSVGSPSASQSRPSTSWQHQLQHPLSQPAWNSSVA
NTPSPVCGDQSPNLFRLPPPPAPAHDRSSGSSSHSRRRRRRQTCQQDGTAAESDTSLSIP
SVDHEELERSFSGFSISQAKEDFFGPSFFAGTAGCPRVRPFIAEGESDTDSDLYAPSPVS
FTGDTSCGERPWPGLK
>Takifugu rubripes_KCNQ2b(ENSTRUP_24560)
MVQKSLNGGVYPAEDGEKKHRVGFVGLDPGAPESSRDGALLIAGPDGAHKRSSILCRRGS
SISTGRPRPTKKNASYRKLQNFLYNALERPRGWAFVYHAYVFLLVFSCLILSVFATIKEF
KNSSESALYILEIVTIVVFGVEYIVRIWSAGCCCRYRGWRGRLKFARKPFCVIDIMVLIA
SVSVLAAGSQGNIFATSAIRSLRFLQILRMLRMDRRGGTWKLLGSVVYAHSKELITAWYI
GFLCLILASFLVYSVEKESNEEFETYADALWWGLITLTTIGYGDKVPKTWNGRMLGAAFS
MIGVAFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQGAWRFYATNLSRTDLVC
TWDFYEQTVSVPMYRFIPPLNQLDLLRNLKGKSFRKESQTEMSPSRKASLKDKVFPSPSK
APFAKGKAQSPGAEEGVEASPYKVAKSWSFTDKNRGTKNSFKARGSTSRQNSEEASLPGE
EMGDDKSCHCEFLTQELPSSLKVTIRAICIMKFLVSKRKFKESLRPYDVMDVIEQYSAGH
LDMLCRIKNLQTRIDMIVGPPPPSTPRHKKSTEGLDLSPITSPIYLKFNARVDQIVGKSP
KADGDPGDDLSMMGRLVKVEKQVLCMDRKLDFLVNVYVQRMGITHSETEAYFNSKEPYPA
PPYHSPDDSKLEKDNKEQMNSLEQKDPLVGRSGARSVGSPSASQSRPSTSWQHQLQHPLS
QPAWNSSVANTPSPVCGDQSPNLFRLPPPPAPAHDRSSGSSSHSRRRRRRQTCQQDGTAA
ESDTSLSIPSVDHEELERSFSGFSISQAKEDFFGPSFFAGTAGCPRVRPFIAEGESDTDS
DLYAPSPVSFTGDTSCGERPWPGLK
>Tetraodon nigroviridis_KCNQ2(ENSTNIP_13799)
MVQKSLNGGVYPEEEGEKKHKVGFVGLDPGAPESSRDGALLIAGPDGAHKRSSILCRRGS
GVSTGRPRPSKKNASYRKLQNFLYNALERPRGWAFVYHAYVGLLVLLCDFLDVSATIKEF
KNSSESALYILEIVTIVVFGVEYIVRIWSAGCCCRYRGWRGRLKFARKPFCVIDIMVLIA
SVSVLAAGSQGNIFATSAIRSLRFLQILRMLRMDRRAGTWKLLGSVVYAHSKELITAWYI
GFLCLILASFLVYSVEKESNEEFETYADALWWGLITLTTIGYGDKVPKTWNGRMLGAAFS
MIGVAFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAACLIQGAWRFYATNLSRTDLLC
TWDFYEQTVSVPMYRGFSFSFFVFRFIPPLNQLDLLRNLKGKSFRKESQTELSPSRKASL
KDKVFPSPSKAPFAKGKAPSPGAEDGVETSPYKVAKSWSFNEKNRGAKNSLKARGSSSRQ
NSEEASLPGEEVGDDKSCHCDFLTQELPSSLKVTIRAVCIMKFLVSKRKFKESLRPYDVM
DVIEQYSAGHLDMLCRIKNLQTRIDMIVGPPPPSTPRHKKSTEGPRDGEAGDDLSMMGRL
VKVEKQVLCMDRKLDFLVNVYVQRMGITHSETEAYFNSKEPYPAPPYHSPDESKLEKDPK
EQMNSLEQKDPLLGRSVARSLGSPSASQSRPSTSWQHQLQHPLSQPAWNSSVANTPSPVC
GDRSPNLFRLPPPPAPAHDRSSGSSSQSRRRRRRQTCQQAESDTSLSIPSVDHEELERSF
SGFSISQAKEDFFGASFFAGPPVCPRDRPFIAEGESDTDSDLYAPSPVSFTGDIFCGEKP
WPGLK
>Gasterosteus aculeatus_KCNQ2(ENSGACP_6133)
FLLVFSCLILSVFATIREFKNSSESALYILEIVTIVVFGVEYIVRIWAAGCCCRYRGWRG
RLKFARKPFCVIDIMVLIASVSVLAAGSQGNVFATSAIRSLRFLQILRMLRMDRRGGTWK
LLGSVVYAHSKELITAWYIGFLCLILASFLVYSVEKESNDEFETYADALWWGLITLTTIG
YGDKVPKTWNGRLLAATFSMIGVAFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGL
IQATWRFYATNLSRTDLLYTWDFYEQTVAVPMYRLIPPLNQLDLLRNLKGKTFRKESQTE
TSPSRKASLKDKVFPSPSKAPLAKGKSQSPDGAEASPGKVDKSWSFADKNRGPKHSFRAR
GSTSRQNSEEASLPGEEIGDDKSCHCEFLSQELPPGLRVTIRAICVMKFLVSKRRFKESL
RPYDVMDVIEQYSAGHLDMLSRIKNLQSRQDRYDCGAPAPSTPRHKKSTEGPSIMLFTPQ
PKYRSKVDQIVGKGPKSEGDSSDDQSMMGRLGKVEKQVICMDRKLDFLVHVYVQRMGIPR
SETEAFFHSKEPYPAPPYHSPEESKLQTCSVPAIPCSDGSLEKKDPLLGRCVPSHSRPST
SWQHQLQHPLSQPAWNSSVANTPSPVAGSADHSPTLFRLPPPPAPVHDRPSRGNGRESGS
RSRRRHRRRQRDAVALESDTSLSIPSVDHEELERSFSGFSISQAKEDFFGPSFFAGSGGG
AGTEAAAGPALCARVRPFIAEGESDTDSDLYAPSPLSFTGEVSCGDPAWPGRK
>Oryzias latipes_KCNQ2(ENSORLP_1054)
MVQKPLNGGVYPAQAEEKKHKVGFVGLDPGAPESSRDGALLIAGSESSKRGSILGRPRSS
VSTGRPRPSKKNASYRKLQNFLYNALERPRGWAFIYHAYVFLLVFSCLILSVFATIREFK
DSSENALYILEIVTIVVFGVEYIVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIAS
VSVLAAGSQGNVFATSAIRSLRFLQILRMLRMDRRGGTWKLLGSVVYAHSKELITAWYIG
FLCLILASFLVYSVEKESNEEFETYADALWWGLITLTTIGYGDKVPKTWNGRLLGAAFSM
IGVAFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGFIQAAWRFYATNLTRTDLLCT
WEFYEQTVALPMYRIIPPLNQMDLLRNLKGKSFRKESQTETSPRFLLSRKPSLKEKVFPS
PSKAPMGKGAEDGAEASPSKPWGFTDKNRGPKHAFRVRSGTGRQNSEEASLPGEEIGDDK
SCNCEFLAQELPPGLKVTIRAICVMKFLVSKRRFKESLRPYDVMDVIEQYSAGHLDMLCR
IKNLQSRIDMIVGPPPPTTPRHKKSTEGPRLDGRETPNSCCRVDQIVGKSPKVDGEVGDD
QSMMGRLVKVEKQVVCMDRKLDFLVNVYAQRMGIAHSETEAFFNSKEPYPAPPYQSLLDI
KEEKNGKEEVKELVKVKTYSAPDVPCSDGPLESNSRPSTSWKHQLQHPLSQPAWGSSMAN
TPSPVGLSGDRSPNPFRLPPPPAPSHDWSSSGHGGGSSRDNASRSRRRHRRQRCQQDAAS
AAAVESDTSLSIPSVDHEELERSFSGFSISQAKEDFFGPPYFTGSGGGGAAGTEAGTGHS
LCARVRPFIAEGESDTDSDLYAPSPLSFTGEVPCGEKGWPGLK
>Homo sapiens_KCNQ5(ENSP_345055)
MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL
LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE
RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW
SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL
RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD
ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ
KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEASSSKFCS
NKQKLFRMYTSRKQSQKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKV
QKSWSFNDRTRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTV
IRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQIT
SDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALAL
ASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQT
FYALSPTMHSQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLP
RPETLHPNPAGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPM
VPKDLGKSLSVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEET
ETDTFDAAPQPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK
>Gorilla gorilla_KCNQ5(ENSGGOP_11126)
YSFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGW
QGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGT
WKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYADALWWGTITLTT
IGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAA
NLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEASSSKFCSNKQKLFRMYTS
RKQSQKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKVQKSWSFNDRTR
FRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHV
AKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKITA
EHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFECE
QTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYALSPTMHSQ
ATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPVIKHLPRPETLHPNPAG
LQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKDLGKSLSV
QNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDTFDAAPQP
AREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK
>Mus musculus_KCNQ5(ENSMUSP_110955)
MPRHHAGGEEGGAAGLWVRSGAAAAAGAGGGRPGSGMKDVESGRGRVLLNSAAARGDGLL
LLGTRAAALGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVL
ERPRGWAFVYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRI
WSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQI
LRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYA
DALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHR
QKHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEASSSKFC
SNKQKFFRVYTSRKQSQKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTK
VQKSWSFNDRTRFRPSLRLKSSQPKPVIDADTALGIDDVYDEKGCQCDVSVEDLTPPLKT
VIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQM
TSDKKSREKITAEHETTDDPSMLARVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALT
LASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLTRSASANISRGLQFILTPNEFSAQ
TFYALSPTMHSQATQVPMSQNDGSSVVATNNIANQISAAPKPAAPTTLQIPPPLSAIKHL
SRPEPLLSNPTGLQESISDVTTCLVASKESVQFAQSNLTKDRSLRKSFDMGGETLLSVRP
MVPKDLGKSLSVQNLIRSTEELNLQFSGSESSGSRGSQDFYPKWRESKLFITDEEVGAEE
TETDTFDGTPPPAGEAAFSSDSLRTGRSRSSQNICKTGDSTDALSLPHVKLN
>Bos taurus_KCNQ5(ENSBTAP_10251)
CLMFQEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVS
AKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLI
FSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISF
FALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSVATWKPHLK
ALHTCSPTKKEQGEASSSQKLSFKERVRMASPRGQSVKSRQASLGDRRSPSTDITAEGSP
TKVQKSWSFNDRTRFRPSLRLKSSQPKPVVDADTALGTDDVYDDKGCQCDVSVEDLTPPL
KTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKG
QITSDKKSREKITAEHEATDDLSMLGRVVKVEKQVQSIEAKLDCLLDIYQQVLRKGSAPA
LALAPFPSPPFECEQTSDYQSPGDGRDLSGPAPGGGLPRSATRERALRQSLDLGGAALLS
VRPAVPQDPGRSVSAQNLARSTEDLDVQLSGSESSGSRGSQEFYPKWRESKLFISDEEAA
SPEDTGTDALDAVPPAREPAPAPDSLRTGRSRSSQSSCPAAGGADALGRPHVRLK
>Gallus gallus_KCNQ5(ENSGALP_49052)
MSLLGKPLSYSSGPSCRRNAKYRRLQNYLYNVLERPRGWAFVYHAFVFLLVFGCLILSVF
STIPEHTKLASGCLFILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVID
IIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL
ITAWYIGFLVLIFSSFLVYLVEKDANNQFSTYADALWWGTITLTTIGYGDKTPLTWLGRL
LSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAASLIQCVWRSYAADEK
SVSIATWKPHLKALHTCSPTKKEQGEASSSKLCSNKQKLFRMYTPRKHSQKLSFKERVRM
ASPRGQSIKNRQSSVGDRRSPSADIATDGSPTKVQKSWSFNDRTRFRPSLRLKSSQPKPV
VDADTSLGTDDVYDDKGCQCDVSVEDLTPALKTVIRAIRIMKFHVAKRKFKETLRPYDVK
DVIEQYSAGHLDMLCRIKSLQSRVDQILGKGQITADKRSREKNTAENETTDDLSMLGRVV
KVEKQVQSIESKLDCLLDIYQQVLRKGSASALTLASFQMPAFECEQTSDYQSPSDSKDLS
NSAQISGCVSRSASANLPRGLQLILTPNEFSTQAYYAISPAMHSQATQVPNDGHTTVNNT
SNQINQATKPATPTTLQIPPFSSVKHINRPEPVHIIPVTTQENISDVTACLVGSKDNGQV
AQPSATKDLTWRKGLDTEGEPLLSVKPVVQMDLGKSLSIQNLIQSTEELNVQITGSDSSG
SRGSQDVYSKWRESKLFITDEELETEAGTETTEAISRPLVETTLSTDSLRTGISRSSQSI
CKPGDGTEALSLLHVKLK
>Taeniopygia guttata_KCNQ5(ENSTGUP_13065)
FSFLLVFGCLILSVFSTIPEHTKLASGCLFILEFVMIVVFGLEFIIRIWSAGCCCRYRGW
QGRLRFARKPFCVIDIIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGT
WKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANTEFSTYADALWWGTITLTT
IGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAA
SLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGESSSSQKLSFKERVRMASPR
GQSIKSRQSSVGDRRSPSADIATEGSPTKVQKSWSFNDRTRFRPSLRLKSSQPKPMVDAD
TSLGTDDVYDDKGCQCDVSVEDLTPALKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIE
QYSAGHLDMLCRIKSLQSRVDQILGKGQITADKRSREKNPAEHETADDVSMLGRVVKVEK
QVQSIESKLDCLLDIYQQVLRKGSASALTLASLQMPAFECEQTSDYQSPSDSKDLSNSAQ
LSGCVSRSASANLPRGLQLILTPNEFSTQAYYAFSPAMHSQATQVPNDGPATVNNTSNQI
NQTTKPATPTTLQIPPFSSMKHINRPEPIHIIPVTTQENISNVTACLVASKDNGQVAQPS
ATKDLAWRKSLDTEGEPLLSVKPVVQMDLGKSLSVQNLIQSTEELNIQIAGSDSSSSRGS
QDVYSKWRESKLFITDEELETESGTETTEAISRPLVETTLSADSLRTGISRSSQNICKPG
DGTEALNLLHVKLK
>Danio rerio_KCNQ5a(ENSDARP_118905)
MPRNHSGDEGGAGLWMKTSQHYGMKDVEAGRGTMNNATRNADSLLSAPGTTGAGGSENQR
RNQGARLSLLGKPLAYSAQSGRRNARYRKLQNYLYNVLERPRAWAFVYHAFVFTLVFGCL
VLSVFSTIPAHMDLSNHCLLILEFVMIVVFGLEYIIRIWSAGCCCRYRGWQGRLRFARKP
FCVIDIIVLIASIAVVSAGSQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYA
HSKELVTAWYIGFLVLIFSSFLVYLVEKEFNKQFATYADALWWGTITLTTIGYGDKTPQT
WTGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAASLIQCVWRSY
AADENSVSIATWKPHLKALHTCSPTNQKLSFRERVRMASPRGQSVKSRQMSVNDRRSPGT
EVAVEGSSPAKVQKSWSFNDRTRFRPSLRLKSQSRTTTEADTTLGPDDAFDDKACHCDVT
VEDLSAPLKAVIRAIRIMKFHVAKKKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTR
VDQILGKGQISVDRKGREKILPEGESLEHDMSMLGRVCKVERQVQSIESKLDSLLDIYRQ
VLQKGSSSMLGLSALPLFELDQTSDYQSSLHSKESSSQLTGSGVSRSCSSNLHRGLHLAL
APSELNLGTGYPHSASSFSPSPLLNNQPSSPDSFYPSSPPPILTPNNLSRSHQRFSELTR
PVPTVHSTSTTLQLPPMVPAPPGRPTSLIPETLQESRAECPTNCLLGTQNEVESDKEAES
IPSTVQLRDKPERNSKEDGSWRRHLSLDIDPLMLMSSTAAASLQVERGLGKSLSAQNLML
PTAADCHPALSTRSSGSSNNESSDREPLTDWGETELFISDKEMDFLHQQSNDTNFSSELL
RTGASGTSPSQAGPRDVLESHNLPHVCLE
>Danio rerio_KCNQ5b(ENSDARP_79805)
MPRNHSGDEAGSGLWMNTSPGHHAESYGLHNVECDNRMKNNCSRPGDGLLSASHAGTGAS
GTERDRGKQGARLSLLGKPLVYGTQSGRRNARYRRIQNYLYNVLERPRSWAFIYHAFVFV
LVFGCLVLSVFSTIPDHQEMASQSLLILEFVMIVVFGLEYIIRIWSAGCCCRYRGWQGRL
RFARKPFCVIDIIVLIASVAVVSAGSQSNIFATSALRSLRFLQILRMVRMDRRGGTWKLL
GSVVYAHSKELVTAWYIGFLVLIFSSFLVYLVEKEFNKDFATYADALWWGTITLTTIGYG
DKTPKTWTGRMLSAGFALLGISFFTLPAGILGSGFALKVQEQHRQKHFEKRRNPAACLIQ
CVWRSYAADENSVSVATWKPHLKALHTCSPTKKDQGESATSQKLSFKDRVRMASPRGQSI
KSRQTSVTDRRSPGAEISTDGSSPAKVQKSWSFNDRTRFRPSLRLKSQSRSTPEGEANVT
VDEAFDEKGCHCDMSVEDLPSALKTVIRAVRIMKFHVAKKKFKETLRPYDVKDVIEQYSA
GHLDMLCRIKSLQTRVDQILGRGQMPVDKKVREKLLSDGDILEDVSMLGRVCKVERQVQS
IESKLDSLLDIYRQVLQKGSSTALTFSSLPPFGLEENSDYQSTVLSKDLSCASQVSQSIC
GNHPRALQLILAPNELMNLNQNNSTTSSPGLNPASASPFNLSTFQVPSTPSLECPSAQGS
PSQILNANSFHCSIGHFPSVGQPPPPLSSTTTSKYQLSTVPSQAGHARSMGPTRSDPADY
AKSCFRGVGIDLGLNSSMICKLQQKNRPSAKEDSSWRRHISLDSEVEMDPLAPVSPLAPV
QGQCSGDRGLGKSLSVQDLIQPALEGVGVDTHSSQASFSTSISSSQDSSAGGIEMGAGGW
GEADLFISDRDLDTSTKAHNQGFDFLSQAPIDASYSSELLRTSTAAGASHSLASGHTSNT
GSNETINMPHVRLK
>Takifugu rubripes_KCNQ5a(ENSTRUP_31899)
AGDAMPRSHSGDQSGGPGLWLKTSTGRRGQEYPLKDVECGRTTMNNAVRVGDGVLSAAAA
GALGVDRKQGARLSLLGKPLTYSAQSGRRNARYRRLQNYLYNVLERPREWAFVYHAFVFI
LVFGCLVLSVFSTIPAHQEFSSHCLLILEFVMIVVFGLEYIIRIWSAGCCCRYRGWQGRL
RFARKPFCVIDIIVLIASVAVVSAGSQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLL
GSVVYAHSKELVTAWYIGFLVLIFSSFLVYLVEKEFNKDFATYADALWWGTITLTTIGYG
DKTPQTWTGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAASLIQ
CVWRSYAADENSVSIATWKPHLKALHTCSPAKKEQGETTYSQKLSFKERVRMASPRGQSM
KNRQLSINDRQRCSPGNDVMGGAELMGGSPAKVQKSWSFNDRTRFRPSLRLKSQTRAAVS
DVDAGMSTEDSLDERGCHCDVTLEDLSAPLKAVIRAVRIMKFHVAKKKFKETLRPYDVKD
VIEQYSAGHLDMLCRIKSLQTRVDQILGKGQIPIDKKIRDKLNPDGDSLEGMSMLGRVCK
VERQVSSIESKLDSLLDVYRQVLQKGPSALTLSSLPLFELHNHQRHSSDYQTSILSRDLP
SPQEGDPMGGENNGGINHSLSVNTRGLRLILAPADDDDPPDSAPPSYPPSTASLSPSPLL
PPDSPYPNLATPNISKRAHFPDLPPPPSSGGGFTLQLPPILHPSQPHCPIEPTSNNQGTM
GPSVVVRSPVDGDTEPGSAQEEAQQCEKPGLKSEGVWRRHINLEVNPLLPPSSSPDWEEC
LGKSLSAHNLCQPSTNRAQSHSSDLHNSSSSHSSKCVNAHGGLSNWDEAELFISDRKLNR
E
>Takifugu rubripes_KCNQ5b(ENSTRUP_20763)
MPRNHNGDEGGTGLWMRTSQGHRSEGSYGLKDVESGQRMLNNAGDGLLSASAAAGAVGSE
SLRVKQGARLSLLGKPLIYSAQSGRRNVRYRRLQNYLYNVLERPRAWAFVYHAFVFILVF
SCLVLSVFSTIPPHQDFSSYCLLILEFVMIVVFGLEYIIRIWSAGCCCRYRGWPGRLRFA
RKPFCVIDIIVLIASVAVVSAGSQGNIFATSVLRSLRFLQILRMVRMDRRGGTWKLLGSV
VYAHSKELVTAWYIGFLVLIFSSFLVYLVENKFNKEFATYADALWWGTITLTTIGYGDKT
PKTWTGRMLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAYLIQCVW
RSYAADENSVSIATWKPHLKALHTCSPTKKEQGESTTSQKLSFKERVRMASPRGQTIKNR
QTSSGNDRRSPVTDINTEGTSPAKVQKSWSFNDRTRFRPSLRLKSQSRSTTDATDSNVAG
EDGFDEKGCNCEISVDDLLPAVKSVIRAVRIMKFYVAKKKFKETLRPYDVKDVIEQYSAG
HLDMLCRIKSLQTRVDQILGKGQIPLDKKIREKLLSDGDILEDMSMLGRVCKVERQVQSI
ESKLDSLLDIYRQLLHKGSSSALTLSSLPLFELEQTSDYPSSVFSKDLSCSSQVSGSGAP
HPGGCVSHSSTNSRLSQGGLRLILAPSSDSSST
>Tetraodon nigroviridis_KCNQ5(ENSTNIP_17165)
FRFILVFSCLVLSVFSTIPAHQDFSSDCLLILECVMIVVFGLEYIIRIWSAGCCCRYRGW
QGRLRFARKPFCVIDIIVLIASVAVVSAGSQGNILAASFLRSLRFLQILRMVRMDRRGGT
WKLLGSVVYAHSKELVTAWYIGFLVLIFSSFLVYLVENKGNKEFATYADALWWGTITLTT
IGYGDKTPKTWTGRMLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAA
YLIQAAWRYYSTDSTRPDLDATWRHYESLLPPHSQKLSFKERVRLASPRGQTLKNRQASS
VNDRRSPVTDISAEGTSPAKVQKSWSFNDRTRFRPSLRLKSQSRSTTDAAEDGFDEKGCN
CEISVEDLLPSVKSVIRAVRIMKFYVAKKKFKETLRPYDVKDVIEQYSAGHLDMLCRIKS
LQTSRVDQILGKGQIPLDKKIREKLLSDGDILEDMSMLGRVCKVERQVQSIESKLDSLLD
IYRQMLHKGSSSALTLSSLPLFELEQTSDYHSPVFAKDPSCSSQAPKTVSIEASTNME
>Gasterosteus aculeatus_KCNQ5a(ENSGACP_23908)
FRFVLVFSCLVLSVFSTIPAHQDFSSYCLLILEFVMIVVFGLEYIIRIWSAGCCCRYRGW
QGRLRFARKPFCVIGEILLIASVAVVSAGSQGNIFATSVLRSLRFLQILRMVRMDRRGGT
WKLLGSVVYAHSKELVTAWYIGFLVLIFSSFLVYLVENKFNKDFATYADALWWGTITLTT
IGYGDKTPKTWTGRMLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAA
YLIQCVWRSYAADENSVSIATWKPHLKALHTCSPTKKEAGESTTSQKLSFKERVRMASPR
GQSIKNRQTSSVNDRRSPVAEAGTDGTSPAKVQKSWSFNDRTRFRPSLRLKSQSRSTTDA
ADSNMAGEDSYDERGCHCEMSVQDLLPSVKSVIRALRIMKFHVAKKKFKETLRPYDVKDV
IEQYSAGHLDMLCRIKSLQTRVDQILGRGQIPLDKKIREKLLSDGDILEDMSMFGRVCKV
ERQVQSIESKLDSLLDIYRQVLRKGASSALTLSSLPLFELEQTSDYHSSVFGKDLSSSTQ
ASSNAALPPGSNSHLSQGGLHLILAP
>Gasterosteus aculeatus_KCNQ5b(ENSGACP_23911)
ELVNLVESLIVLPGFSVILYPLLEFVLVFSCLVLSVFSTIPAHQDFSSYCLLILEFVMIV
VFGLEYIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDIIVLIASVAVVSAGSQGNIFATS
VLRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLVLIFSSFLVYLVEN
KFNKDFATYADALWWGTQKPHSDPSGRDDEITLTTIGYGDKTPKTWTGRMLSAGFALLGI
SFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAYLIQAAWRCYSTDSTRPYLDATWRP
YKSLLTSYSQKLSFKERVRMASPRGQSIKNRQTSSVNDRRSPVAEAGTDGTSPAKVQKSW
SFNDRTRFRPSLRLKSQSRSTTDGPREDSYDERGCHCEMSVQDLLPSVKSVIRALRIMKF
HVAKKKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGRGQIPLDKKIREKL
LSDGDILEDMSMFGRVCKVERQVQSIESKLDSLLDIYRQVLRKGASSALTLSSLPLFELE
QTSDYHSSVFGKDLSSSTQASSNAALPPGSNS
>Oryzias latipes_KCNQ5a(ENSORLP_3087)
KIKMCFGNVISKKRGPPFPPKKVLKFILVFSCLVLSVFSTIPAHQEFSSYCLLILEFVMI
VVFGFEYIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDIIVLIASVAVVSAGSQGNIFAT
SVLRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLVLIFASFLVYLVE
NKFNKDFATYADALWWGTTFRTPCLYLQITLTTIGYGDKTPKTWTGRMLSAGFALLGISF
FALPAGILGSGFALKVQEQHRQKHFEKRRNPAAYLIQCVWRSYSADENSVSIATWKPHLK
AMHTCSPTNQKLSFKERVRMASPRGQSIKNRQTSSMNDRRSPVADGGAEGTSPAKVQKSW
SFNDRTRFRPSLRLKSASRSTTDVLWPGDDGFDDKGCHCDLSVEDLLPSVKAVIRAVRIM
KFHVAKKKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQIPLDKKIRD
KLLSDGDLLEDMSMLGRVCKVERQVQSIESKLDSLLDIYRQVLRKGSSSGLTLSSLPLFE
LEQTSDYNSPVFSKDLSTPSQPITIATSSSSSHA
>Oryzias latipes_KCNQ5b(ENSORLP_2826)
FILVFGCLVLSVFSTIPAHQEFSSHCLLILEFVMIVVFGLEYIFRIWSAGCCCRYRGWQG
RLRFARKPFCVIDIIVLITSVAVVSAGSQGNVFATSALRSLRFLQILRMVRMDRRGGTWK
LLGSVVYAHSKELVTAWYIGFLVLIFSSFLVYLVEKEFNKDFDTYADALWWGTCPLWSSP
IQITLTTIGYGDKTPQTWTGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFE
KRRNPAASLIQQIEWRVKVVYQFNTHLLAFWELFELYDGLLLASPSQKLSFKERVRMASP
RGQSMKSRQTTIGDRQRCSPGSEVVGSNELMSGSPAKVQKSWSFNDRTRFRPSLRLKSQL
SGDGGAATEDSFERGCHCDVTVEDLSAPLKAVIRAVRIMKFHVAKKKFKETLRPYDVKDV
IEQYSAGHLDMLCRIKSLQTRVDQILGKGQIPVEKKPRDKLHPDGDSLEGMSMLGRVCKV
ERQFSGVLHRVQTRLLLDIYRQVLQKGSSGLSSLPLFELENHQRHGSDFPLSPHRGDAIR
SRDEGGGMQRSLSASPR
>Homo sapiens_KCNQ1(ENSP_155840)
MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPG
PAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGW
KCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGC
RSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLH
VDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYA
DALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQR
QKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKK
KKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFM
RTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRD
VIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVT
QLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLP
TYEQLTVPRRGPDEGS
>Callithrix jacchus_KCNQ1(ENSCJAP_21515)
MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPG
PAPPASPAAAPTVPSDLGPRPPVSLDPRVSIYSTRRPLLARTHVQGRVYNFLERPRGCKC
FIYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYMVRLWSAGCRS
KYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVD
RQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGHVEFGSYADA
LWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQK
HFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYVRKPPRSHALLSPSPKPKKSVVIKKKK
LKLDKDNGVSPGEKTLTVPQITCDPPEERRLDHFSVDSYDSSVRKSPTLLEVSMPHFMRT
NSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVI
EQYSQGHLNLMVRIKELQRRLDQSIGKPSLFIAVSEKSKDRGSNTIGARLNRIEDKVTQL
DQRLVLITDMLHQLLSLHRGGPPGGSSPPREGGAHITPPCGSGGSIDPKLFLPSSALPTY
EQLTVPRRGPDEGS
>Mus musculus_KCNQ1(ENSMUSP_9689)
MDTASSPPSAERKRAGWSRLLGARRGSAVVKKCPFSLELAEGGPEGSTVYAPIAPTGAPG
LAPPMSTPVSPAPAPADLGPRPRVSLDPRVSIYSARRPLLARTHIQGRVYNFLERPTGWK
CFVYHFTVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCR
SKYVGIWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHV
DRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRIEFGSYAD
ALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQ
KHFNRQIPAAASLIQTAWRCYAAENPDSATWKIYVRKPARSHTLLSPSPKPKKSVMVKKK
KFKLDKDNGMSPGEKMFNVPHITYDPPEDRRPDHFSIDGYDSSVRKSPTLLEVSTPHFLR
TNSFAEDLDLEGETLLTPITHVSQLRDHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDV
IEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFIPISEKSKDRGSNTIGARLNRVEDKVTQ
LDQRLVIITDMLHQLLSMQQGGPTCNSRSQVVASNEGGSINPELFLPSNSLPTYEQLTVP
QTGPDEGS
>Rattus norvegicus_KCNQ1(ENSRNOP_27875)
MDTASSPPNAERKRAGWGRLLGARRGSAGLAKKCPFSLELAEGGPTGGTVYAPIAPTGAP
GLAPPMSPPVSPVPAPADLGPRPRVSLDPRVSIYSTRRPLLARTHIQGRVYNFLERPTGW
KCFVYHFTVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGC
RSKYVGIWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLH
VDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRIEFGSYA
DALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQR
QKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYVRKPARSHTLLSPSPKPKKSVMVKK
KKFKLDKDNGLSPGEKIFNVPHITCDPPEDRRPDHFSIDGYDSSVRKSPTLLEVSTPHFL
RTNSFAEDLDLEGETLLTPITHVSQLRDHHRATIKVIRRMQYFVAKKKFQQARKPYDVRD
VIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFIPISEKSKDRGSNTIGARLNRVEDKVT
QLDQRLVIITDMLHQLLSLQQGGPTCNNRSQVVASDEGGSINPELFLPSNSLPTYEQLTV
PQTGPDEGS
>Canis familiaris_KCNQ1(ENSCAFP_42679)
GHRRCPGLRRGSAGGAFRCALRPHQGQSRTLGGEGLHPRGPGAPGPGLPRPQAAPASPPD
LLGPFLPLPVTPNARPAAGPGVCPRPRRSYPSVRCWNFRVRLPTDRRVLPPHSFLIVLVC
LIFSVLSTIEQYVALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGIWGRLRFARK
PISIIDLIVVLASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVF
IHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNDSGQVEFGSYADALWWGVVTVTTIGYG
DKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQ
TAWRCYAAENPDSSTWKIYVRKPARSHALLSPSPKPKKSVMVKRKKFKQDKDNGVSPGEK
MLTVPHITCEPVSEERRPDHFSVDNCDSSVKKSPMLLEVSTAHFMRTNSFAEDLDLEGET
LLAPITHVSQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVR
IKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLVLITDMLHQ
LLSLYHGGPPGGRPPSGSGVQVVQPCSSINPELFLPSNTLPTYEQLTVPRRGPEEGS
>Xenopus tropicalis_KCNQ1(ENSXETP_43172)
IFQLLKKPLSWKPFVYYTPKFLIVLICLIFSVLSTIQQYNNLATETLFWMEIVLVVFFGA
EYVVRLWSAGCRSKYVGIWGRLRFARKPISVIDLIVVVASIIVLCVGSNGQVFATSAIRG
IRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAID
SSGEYQFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGS
GFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSATWKIYIRKQSRNHHILSPS
PKPKKSAMVKKKKIRTDREEGSTDKMLNIPNITYDHVADDRKNDGYSVEAYENTVRKPFG
FLDPGTGPFIRTSSFTDDLDMEGDTLLTPITHISELKEHHRAAIKVIRRMQYFVAKKKFQ
QARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSLGKPSLFLSVSDKVKDKGSNTIGS
RLNRVEDKVTQMDHKLNLITDMLHHLVTNQQGTQSIRTPHRSNSLNSENHASRNTLPTYE
QLTVPRPGQDNVS
>Danio rerio_KCNQ1(ENSDARP_77949)
MTSPAHSTATEASWTAGAADLQMTEALHLRNDGVRFPSSVPVDPAVITQHPPSHLHPRMS
VYSATRPTLSRSFLQGRVYNFLERPTGWKCFVYHFTVFLIVLSCLILSVLSTIDEYQALA
NKTLFWMELVLVMFFGVEYVVRLWSAGCRSKYVGILGRLRFARKPISVIDLIVVVASIIV
LAFGSNGQVFATSAVRGVRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLG
LIFSSYFVYLAEKDAVDDHGNSGFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCF
SVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQASWRCFALLNPDSATY
KLFVKRNLSSSGSSPKLKVKMRRKMKISDRNNGQNSPAVPSITYDSFDDGRDSRQETLTS
LQQSVISDGTNTTRRYERAPSWNSLSSFQFSTPPATKPGVFEVSSRPTLQRSSSIADDME
TEPEREIVLIPVAHVSQLRDSHRAAIRVIQRMYYFVARKKFQQARKPYDVRDVIEQYSQG
HLNLMVRIKELQRRLDHSLGKQSLFQTSSERLKDKGTNTIGSRLNRMDEKITHMDRTLNS
IAESLNLMLARERRGDLARGKEQRSTMRRQSATFSLSVLDSSEQLSTTTAIHEDS
>Takifugu rubripes_KCNQ1(ENSTRUP_41806)
KPPLDLQLSEIGPGAPDVEPPARNDGRKMPADATANSEVPPAYLHPYSAHPRMSFRMSVY
STGVRPVLTRAYIQGRVYNFLERPSGWKCLLYHFTVFLIVLACLILSVLSTIDQYQSLSQ
TTLFWVEIVLVVFFGMEYFIRLWSAGCRSKYVGVWGRLRFARKPISIIDLIVVVASVIVL
SVGSKGQVFATSAVRGIRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLSL
IFSSYFVYLAETYAISGGSTEFRNYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSV
FAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAAGLIQTSWRCFAVENLDSATYKM
FLRKRSNITASSLSSPKSKKSVKIKRKPKSADQDNGPTSPTVPSITYDSVFDSGRELSSD
VYSTTVRRSPGLLDVHGHDPLRRNASFANDTELESEHHNHLFPAASLSQLTESHRKAIRV
IQRMRYLVAKRNFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSLGKMTLFQAG
SERAKDRGNNSIGSRLNRMEDKISHMDQTLGRISESLAVLLEQK
>Tetraodon nigroviridis_KCNQ1(ENSTNIP_12469)
PRMSFRMSVYSTGVRPVLTRAYIQGRAYNFLERPSGWKCLVYHFSVFLIVLACLILSVLS
TIDQYQSLSQTTLFWVEIVLVVFFGMEYFVRLWSAGCRSKYVGIWGRLRFARKPISIIDL
IVVIASVIVLSVGSKGQVFATSAVRGIRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELI
TTLYIGFLSLIFSSYFVYLAETYSVSGGSTDFRNFADALWWGVVTVTTIGYGDKVPQTWI
GKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAACLIQTSWRCFAV
ENLDSATFKMFLRKRSNISASSLPSPKSKKSVKIKRKPKSVDKDSGPTSPTVPSITYDSV
FDSGRELSSVPACVQTERRAPGLLDVHSHDALRRNASFADDTELESEPHTHLFPAASLSQ
LTESHRKAIRVIQRMRYFVAKRNFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQ
SLGKMTFFQAGSERAKNRGNNSVGSRLNRMEDKITHMEQTLGCIADSLALLLKQRDAGEA
EGGGRLRPQRARHFVPSHDSLPSYDQLSSSPSSFSSNN
>Gasterosteus aculeatus_KCNQ1(ENSGACP_22656)
WCGVCSPRRGGVDRLRTAVAQFGTNNKTSERPATRGAPPDPLPGPRLHIPSTTRERMPED
GNAAATDGPNVYLHPYLSHPRMSVRMSVYSTGIRPVLTRAHIQGQVYNFLERPSGWKCFV
YHFTVFLIVLACLILSVLSTIDQYQALAHTTLFWVEIVLVVFFGVEYFVRLWSAGCRSKY
VGICGRLRFARKPISIIDLIVVVASIIVLSVGSKGQVFATSAVRLKFSDNVTTSHEKDPI
GQWIDLSVLYCVFQELITTLYIGFLSLIFSSYFVYLAEKDAVDSSGYSEFENYADALWWG
VVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNR
QIPAAACLIQTSWRCFAVENFDSVTFKKFLKKRAHIPASSLSTLKPKKSVKVKTRRKPRS
SDKDNGPTSPTVPSITYSNVFDSGREFIFLSNIKGFNSTFEASAGLLDVHSPGPLRRNCS
FADDLDAEAERDGELAPVTSLSQLTESHRRAIRVIQRMRYFVARRNFQQARKPYDVRDVI
EQYSQGHLNLMVRIKELQRRLDQSIGRQTLFQSGSDRAKDKGTNSIGSRLNRMEDKITHM
DHTLNRIAESLTSVLHRRDGPEEPRRPPQ
>Branchiostoma floridae_(XP_002588016)
MARTDAAYRPRKMSNISALSDADSPFSVLPRPAQLTVPETTSRMSMSDTETEFLFPPKLSISEAEDDISL
NMGDGAGRQEPPGRCSIGPDTDAETGAKEVTGLLTPEPRRNMGDGAGRQEPPGRCSIGPDTDAETGAKEV
TGLLTPEPRRSVGNCAPAGRRSVKQVEFIGLRQLTVEEEEYQAAVARKQGTVGRYALPRMSLLGKPIGYR
ATRRAARYRHFQMMVYNFLERPAGCKTLAYHIIIPDQPGAGGVTHDWGETPQQDSTRTPCDQEEWSNLLT
GREAVKTSSDWEDLAPTPKTTGAHCWKENIPSKVWFLRGKRKRKARKVQSATSAAPIPDITVTMAGKRVN
WEDSVSQETSNSAETISMEDMVSERVGGESRASPGSPPPGYDTLLAVKGPQAVEDVVSIGSHSSDQVFAD
SGLTDDVHLCNNVKVDVDVPETQLRRRGMLDAEGPGGPPRMTLLGKPIPHVYHSNKNRRTLYIKTQIFNF
FEVPQKQLLSKDSTRTPCDQEEWSNLLTGREAVKTSSDWEDLAPTPKTTGAHCWKENIPSKVWFLRGKRK
RKARKVQSATSAAPIPDITVTMAGKRVNWEDSVSQETSNSAETISMEDMVSERVDRVESRASPGSPPPGY
DTLLAVKGPQAVEDVVSIGSHSSDQVFADSGLTDDVHLCNNVKVDVPETQLRRRGMLDAEGPGGPPRMTL
LGKPIPHVYHSNKNRRTLYIKTQIFNFFEVPQKQLLSKCENGTNATDNSQHNCPKTEEQDKLPNQALYVM
CENGTNATDNSQHNCPKTEEQDKLPNQALYVMEIIIVIVFGMEYILRMWAAGCRSRYQTWRGRLRFARRP
FVIIVLSLGSHGNVFAASALRGLRFLQILRMVRMDRRGGTWKLLGSVVWAHRQELLTTAYIGFLALIFAS
FSLYLIEKDENPEDFGNFAKALYWGVITLLTVGYGDATPDTWLGKLVAVGFSLLGISFFMLPAITMTTVG
YGDATPDSWQGKLLTVVFGLCGISFFALPAGILGSGFALKCLWRCYAGDKNSRSIATWLPHLRAVPDRKD
AAAKKKSFKSQLSRFSTSSPLARPTVSRLQGLEVGDGVDQQFTTQVSAESSGSTGRQMSVADSGKPLSGK
KPAGVRWRETVNAVMTSYESPGSDKSGLRDKYRVRYTVEDMAGYALSEEEYHQPWGLARLSPAHKNAIRA
IRKIKYFVARRKFREALRPYDVKDVIEQYSAGHVDLLARVKHLQSRLDEILGSSSRSPGHAKDKYANDPK
MPLQNRVIRLEKQVHNIDQKLDVLINLMHQKPPDPGSHGDKEIGDHGNKANSDPSVHGDGANTACHSNQI
SLIPDSTRSKDCVELQQAPQSGRTRALPRQSATVISESDPSEGDAAETTSCQQDGKEAQDCVETGEETAG
NGHQTGNGRAKLSSDSDSSLRMLGRETDIV
>Saccoglossus kowalevskii_(XP_006820358)
MAVSVIIIAIGTSGQMFAFSALRGLRFLQILRLVRVDRRGGTWKLLGSVVWAHRQELITTWYIGFLSLSV
LSFLVYNAEMEKNKEDFETFADAMWWGLVTLTTVGYGDKVPVTWVGKLVAAVFAIVGISFFALPAGILGS
GFALKVQQQQRQKHFLRRRHPAAELIQGILGSGFALKVQQQQRQKHFLRRRHPAAQLIQCVWRCYAADPC
SMSVATWKPHLRPVNSPTTNRTNPSLISRLSTKRKIGSPMVRRHNPLNQHDALKKSHSHDLDVGDSLNKS
SLSLHDGNGPLSRNQDSLYSPKNRDDDSIKEDEPVVPEPQTTEWFVTQNIAALKRLLDDDETMGLTRLTE
PHKNAVRAIRKIKYFVARRKFKEAFRPYDVKDVIEQYSAGAAEMQFRMKAIQARLDEILGKTEGKNGIEL
YNTKVPMITRVIKVEKKVNMIDRKLDMLIELYREERQEKMKALQQNKHEHDDQNDSDKDTKDPPSRIRRH
GRARKLSRVKSEGHGAHVDTHEKSERRVEFRKLSDSQPSIPSSLNLDAPDATTVTVSTALSQPSITTTTE
SEQGLQLANAKGVGRGQNIPDYDSAIDDTRV
>Drosophila melanogaster_(FBpp0301793)
MDPDNDIYAFYDIRGYKGKCRPGRPNSERILQPRMSLLGKPLNYNRGTRRDVRYRRLQSR
LYNFLERPRGLHAIFYHVMVFLMVFTCLALSVFSTIKEYEEDAVYILFRMEILVVIWFTM
EFGARLWSSGCRSRYQGCLGRLKFVKRPFCIIDIVTILASIVVLGMGTSGQVFATSALRG
LRFFQILRMVRMDRRGGTWKLLGSVVYAHRQELITTMYIGFLGLIFASFLVYMWEKDVND
KFSNFAQALWWGVITLCTVGYGDMVPITWQGKLIASCCALLGISFFALPAGILGSGFALK
VQQQQRQKHMIRRRQPAATLIQAVWRCYAADEHSVSVATWNIHRVALPSPPASRASSSFK
HNTSFVARLPTIRRHKSQTIQTPGGGDGGGVSKPPGSSRASTRYTRTIRDINASVENLEV
VQNGKSMNPSFSEDSVAETTCLKNIKNSDDEEDEPRCTQLTNRHKTAIRFIRKLKYFVAR
RKFKEALKPYDVKDVMEQYAAGHVDLLGRVKMLHLRLDQILGKQGSKAKDVYASKISLAS
RVVKVERQVADIEEKLDILIKAYMEDRDRFLALPLPAKPKIHSISPSHKPLHHAHNLAMI
DVWKRTAALSVHPEQVTTTPLLNPSAPDSSELRSLTATQTPTTTTDAIATQTPMPPHVQH
TATNTKSSVLNSYQLGSEKQQHNDVFMTELENRTKKRVTLSLHRSTSEPYSKQEQRITIP
DEGADSLDSSAKPTPPDSSIILIDEYEDFEEEDLNCEGEMDHFPTWEIDSDIGVEVDVDA
DADGDCDESTEDTALLQCATRTAIVITPISPVSSAHNLQQLNDQTTTLNKSNLLPPDSG
>Apis mellifera_(XP_006565037)
MKDRPHRPYRDHHGQAMPLEEVQGLLLPPSRTGNRGPLTIVQVGKGNGGGGDGGSDLLKLEPPSDLRPTP
SPLSETSATLQSDNNDTFSGGVDPRLLLGANTGGDRNTWEGRYRVKEHRRAGKATFQGQVYNFLERPTGW
KCFLYHFSVFMVVLVCLIFSVLSTIEQYSNFANETLFWMEICLVVFFGVEYLVRLWSAGCRSKYMGCCGR
LRFIRKPICIIDLIVVVASMVVLSVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQ
ELITTLYIGFLGLIFSSYFVYLAEKDVIGPDGKTDFSSYADALWWGVITVTTIGYGDTVPQTWMGKIVAS
CFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAAMLIQCLWRCYAADKAINSVATWNIYIKD
PAPAGQPSTPLGKLICVKKMSLMIQVAKKASVLKRRKSRNRMDVQQQQQQSLPPVTISGGMSSGGATGDQ
NDNQRMENEGDVIFYMEEPKAGTPNRARRDNRGSLFTSQTSSVTEATSDEIDIDIEEPQRVTTLTEAHRN
AIRAIRKIKYFVARRKFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDQTLGKPGSYLAGIDRAGN
VKPMTIGARLYRVEQQLSVMDKKLDQLVYVLNAVAQKQQIPLRSIEDDV
>Hydra magnipapillata_(XP_012559369)
MKHQCEIELNNKEKMSFLNRNTLQKSKTIHKTRMSVFYFLEKPQTIFALLYHKVMFVLVLVSLSLSILIT
IESFARNTKIHSAIYYIEVSLAIVFTAEYSLRVWSCSIQSKYAGVSGRLRFIKRPYVILDMIVILATIFI
IYSHKIIRDDLHTTLFQFLNFLQILRILRLDRQQGAFKIMSLVVYEHRQELMTCWYLSFILLAACSFLVY
IAEKNDSIVSSNKIKNLGEGIYFGMITLLTIGYGDFSPNSWIAKIIVVVFAFIGTAFFALPAGILGSGFA
LKVAQNQKKKHFNRRRVPAALIIQYVWRNYSTQVNPSSNTWTNYRMIIKEKHQTLSMNNTPILSKQNNSN
KNVVGLHKKNQVDRKPFKETTCATIPSAVNFRNRPNSDGNLIVMFPTNIEEHQGTIVSLPASTDVDLKEF
LKSRINVENQRSCTRQLNRIEKIAVRFLIKIKIKVALRKFKVVCRPYDIKDVIEQYTSGQIEMFGFIRKF
QSRIENALGIQDGRLMIPSLDVRMDIFEKKIDTLSVKLDNVMELLNSNSQLT
>Trichoplax adhaerens_(XP_002117304)
ERVAINVSGLRFETYESTLIKHPNTLLGNRARRDRYYDYERKEYFFDRHRQSFEAILYYYQSEGRLNRPS
TVPWDIFYEELCFFQIEPEVLSHLRKVEGMEEDPAPLLPQNKIKRRIWLLFEYPDTSMMAKCVAFFSMAI
ILLSVAVFCLETVDGFNVNFRNKSNVTVEQNRTATRNADALYNVETMCVVWFTFELIIRFLACPSKWKFV
ISPMNIIDFLAIMPYYITLIMRTNGNPNVTTVEALRVLRLARVLRIFKLSRHSSGLQTLGKTFKSSMNEL
FMLGCILVICVILFSSFVYFFEYERNGKEFQSIPHAFWWAVITMTTVGYGDISPRTGLGQIIGSLCAVTG
VLCIALPVPIIVSNFTYYY
>Amphimedon queenslandica_(XP_011404311)
MADRVEHRISQQHSLPNSPLLRKRKKIRRRSRPEVYDQSAPVPASPSLTSLSCSSSDSECESNREEEEDP
LPDKDGQSVTVKQALEGLFYNKAVQLVHHHDCILYVAEAIYIDRLLKSADEEEFILGCFNQTWVNITEPS
YLNLLIIPKDYTLWSLQLFLALICLIGAFTVIYVHQEPYGSVPVLRHVFRYMTHSIVICVLIGLAFFVTL
LMPQCLHILWIPTFLFCWPARHNFMYIVQQKSEVSFFRSFHGFRTTAISLATFLLCFMFSCLCLIHHFER
LGKKISLFDTYWFVVVTFSTVGYGDISPAHWTGKVIITIFIIAALMYLPPKVDKLWRSFTLHRKHYKQYN
KANITKHVVLAAVDLKPLVLRDFLSELYSDPGQMDTQVVVLIKEEPADYIKAILLHPIWSQRVAILRGTA
LRPSDLARVKLRTADACFLHSSRTGRAADADQHTIMSAWTVKNYAPKTRLFVHVRQPESKFQLNIADEVI
CDGELTSAVLALNSVCPGLLTLSALLVHTFTYEGRRFNIPEYKRYEECSPVEIYHVKLGESRYFHRFAGK
NFLFTSVVAYRKFHVLLLGICPSGGTDILFNPGINHIMDRNDECYYISDTHEHNSDHQIIPASTFQSSLW
RTSATLGLLAMYISGIDPDQMFHQTQEYEERDSDNKGGFPRSASNDRLKKLSSPDSIPEIQVEGVASGLS
LTEEVGLPSIGEEEEVLDEQLAVEVTNWQHDVQHGLQLLKYHGEGELPERKPCVKLSVKSHFEGHHSPRS
HSLPVAATTCTVMEPHPLAHPLPSLGVIPEDEPDVIVIGEEEPHLLSHLQRVGDKQQHSSGGGGGKHRVH
SQPALFHFGFNKRQSESKHDDHLLKAKKHSLKLHDNTSMKSYVSSNASVKSDMSNHSIDDVVSLEVEDLS
DIEELEDLEEGRQHETEGGFISEAETESIDVPPIPYCGCEPLKCHLMKNARTYEDIIIDRSFIGEDITRQ
WYHHAIIVYSDVVSDGLFHFITPLRAAYLPPSSLKPIVFLLGNMPERHFISTISQLPMIYFMVGSISSTS
DLLRAGIMVAESLVVFSSNKMRQSDEGEHLADAEHITAIEKIARLFPHVKISCDIKYRFNIRFIRTTPFE
DLCMQRLRHMARKVDHLTYLFLPQFASSKAFSSSMLDTLLYQSYQKPYIIKLFRQLLGCTQVKGSGFLWK
VPVNNELAKLHTYVRVFQRLVASFSFTSMALYRTANVDHNIDPQYVKGYCEEELEKLRLFLISELHSLGI
KRNVEPLKRPSTQQFLYVNPPPDFPVIEGDIILGIRPPLSNKPPPPSDDVKTEPFSPPPASQISELVRAY
SASAFYGGGSPIPTAMPLGPGGVVLQDTRLHFGLMRKFSFTGSLPQQHQTNTGSCSADSCDM