>Homo sapiens_SH2D3A(ENSP_245908)
MQVPQDGEDLAGQPWYHGLLSRQKAEALLQQNGDFLVRASGSRGGNPVISCRWRGSALHF
EVFRVALRPRPGRPTALFQLEDEQFPSIPALVHSYMTGRRPLSQATGAVVSRPVTWQGPL
RRSFSEDTLMDGPARIEPLRARKWSNSQPADLAHMGRSREDPAGMEASTMPISALPRTSS
DPVLLKAPAPLGTVADSLRASDGQLQAKAPTKPPRTPSFELPDASERPPTYCELVPRVPS
VQGTSPSQSCPEPEAPWWEAEEDEEEENRCFTRPQAEISFCPHDAPSCLLGPQNRPLEPQ
VLHTLRGLFLEHHPGSTALHLLLVDCQATGLLGVTRDQRGNMGVSSGLELLTLPHGHHLR
LELLERHQTLALAGALAVLGCSGPLEERAAALRGLVELALALRPGAAGDLPGLAAVMGAL
LMPQVSRLEHTWRQLRRSHTEAALAFEQELKPLMRALDEGAGPCDPGEVALPHVAPMVRL
LEGEEVAGPLDESCERLLRTLHGARHMVRDAPKFRKVAAQRLRGFRPNPELREALTTGFV
RRLLWGSRGAGAPRAERFEKFQRVLGVLSQRLEPDR

>Pan troglodytes_SH2D3A(ENSPTRP_17653)
MQVPQDGEDLAGQPWYHGLLSRQKAEALLQQDGDFLVRASGSRGGNPVISCCWRGSALHF
EVFRVALRPRPGRPTALFQLEDEQFPSIPALVHSYMTGRRPLSQATGAVVSRPVTWQGPL
RRSFSEDTLMDGPARIEPLRARKWSNSQPADLAHMGRSREDPPGMEASTMPISALPRTSS
DPVLLKAPAPLGTVADSLRASDGQLQAKAPTKPPRTPSFELPDASERPPTYCELVPRVPS
VQGTSPSQSCPEPEAPWWEAEEDEEEENRCFTRPQAEISFCPHDAPSCLLGPQNRPLEPQ
VLHTLRGLFLEHHPGSTALHLLLVDCQATGLLGVTRDQRGNMGVSSGLELLTLPHGHHLR
LELLERHQTLALAGALAVLGCSGPLEERAAALRGLVELALALRPGAAGDLPGLAAVMGAL
LMPQVSRLEHTWRQLRRSHTEAALAFEQELKPLMRALDEGAGPCDPGEVALPHVAPMVRL
LEGEEVAGPLDESCERLLRTLHGARHMVRDAPKFRKVAAQRLRGFRPNPELREALTTGFV
RRLLWGSRGAGAPRAERFEKFQRVLGVLSQRLEPDR

>Macaca mulatta_SH2D3A(ENSMMUP_11407)
EAFATPVSALPRTGSDPVLLKAPAPLGTVANSLRASDGQLQAKAPAKPPRTPSFELPDAS
ERPPTYCELVPRVPCVQGTSLSQSCPEPEAPWWEAEEDEEEENRCFTRPQAEISFCPPDT
PSCLLGPQNRPLEPQVLHTLRGLFLEHHPGSTALHLLLVDCQATGLLGVTRVQRDNMGVS
SGLELLTLPHGCRLRLELLERHETLALAGALAVLGCSGPLEERAAALRGLVELALALRPG
AAGDLPGLAAVMGALLMPQVSRLEHTWRQLRRSHTEAALAFEQELKPLMRALDEGVGPCD
PGEVALPHVAPTVRLLEGEEVAGPLDESCERLLRTLHGARHMARDAPKFRKVAAQRLRGF
RPNPELREALTTGFLRRLLWGSRGAGAPRAERFEKFQRVLGVLSQRLEPDS

>Callithrix jacchus_SH2D3A(ENSCJAP_30061)
MQVPQDGEDLAGQPWYHGPLSRQKAEALQQDGDFLVRASGSRGGHPVISCRWRGSALHFE
VFRVALRPRPGRPTALFQLEDEQFPSMPALVHSYLTGKRPLSQATGAVVSRPVTRPGPLR
RSFSEDTLMDGPARTEPLRVRKWSSSQPADLAHIGRSREDPPGMGASTMPVSALLRSGSE
PVLLKAPASLGTINNSLRGSDGQLQAKAPTKPPRTPSLELPDVPERPPTYCELVPRVPSV
QGTSPSQSRQETEVPWWEAEEDEEEENRCFTRPQAEIAFCPPDAPSCLLGPQNRPLEPQV
LRTLRDLFLEHHPGSTALHLLLVDCQATGLLGVTRDQRGNMGVSSGLELLTLPHGHRLRS
ELLERHETLTLAGALAVLGCSGPLEERAAAVRGLVELALALRPGAAGDLPGLAAVMGALL
MPQVSRLEHTWRHLRRSHTEAALAFEQELKPLMRALDEGAGPCDPGEVALPHVAPVVRLL
EGGEEVAGPLEESGERLLRTLHGARQMARLAPKFRKVAAQRLRGFRPNPELSEALTTGFL
RRLLWGSRGAGAPHAERFEKFQRVLGVLSLRLEPDR

>Canis familiaris_SH2D3A(ENSCAFP_27451)
MQVPQDGEDFASQPWYHGPLSRQKAEALLQQDGDFLVRASRSRGGHPVISCRWQGSALHF
EVLRVALRPRPGRPTALFQLEDERFPSLPSLVLSYVTGQRPLSQATGAVASRPVIRQGPI
RRSFSEDTLLESPARIELPRARKRSDSQPAGLEHMGLSGEDHSGPGASPVPTCALPRMGS
DPVLLKTPASLGSVVDGLRASDGQLHAKAPNKPPRTPSLVLHDASGRPPTYCELVPRVPS
AQETPTGHSGPETEASWWEANEEEEEEDRSFARPKAEVFFCPPNNLFCLLGPQNRPLEPK
VLSTLRDLFLEHHPGSTALHLLLVDCQATGLLGVTKAQRGAMGVTSGLELLTLPHGHRLR
LELLERHEALALAGALAVLGCSGPLEERAATLRGLVELALALRPGAAGDLPGLAAVMGAL
LMPQVSRLERTWRQLRRSHTQAALAFEQELKPLMRALDEGAGPCAPGEVALPHVVPAVRL
LEGQELPGPLDESCERLLRTLHRARLVARDAPQFREAAARRLRGFQPNPQLREALTTGFV
QRLLWGSQGVGAPHATRLEKFQRVLSALSQRLEPDV

>Felis catus_SH2D3A(ENSFCAP_19127)
MQVPQDGEDFASQPWYHGPLSRQKAEALLQQDGDFLVRASGSRGGHPVISCRWQGSALHF
EVLRVALRPRPGRPTALFQLEDERFPSLTSLVLSYVTGQRPLSQATGAVASRPVIRQGPI
RRSFSEDTLRGSPALTELPRTRKWSDSQPAGLEHMGRSREDHCGPEASAMPLCALPRTGS
DPVLLKTPAPLGSVADSLRASDGQLHAKAPTKPPRTPSLVLRDASGRPPTYCELVPRVPS
AQGTPPGHSSPETEAPWWEAEEEEEEESRSFARPQAEVSFCPPNNPSCLLGPQNRPLEPR
VLSTLRGLFLEHHPGSTALHLLLVDCQATGLLGVTKAQRGAMGVASGLELLTLPHGHRLR
LELLERHEALALAGALAVLGCAGPLEERAATLRGLVELALALGPGAAGDLPGLAAVMGAL
LMPQVSRLERTWRQLRRSHTEAALAFEQELKPLMRALDEGAGPCDPGEVALPHVVPAVRL
LEGEELPGPLDESCERLLRTLHRARQMAQDAPKFREAAARRLRGFHPNPQLREALTTGFV
QRLLWGSRGVGAPQAARLEKFQRVLSVLSQRLEPDG

>Bos taurus_SH2D3A(ENSBTAP_18405)
MQVPQDGEDFVGQPWYHGPLSRQKAEDLLQQDGDFLVRASKSRGGHPVISCRWRGSALHF
EVLRVALRPRPGRPTALFQLEDERFPSLPALVRSYVIGQRPLSQATGAVASRPVPRQGLI
RRSFSEDTLPDDPARTEPLRDRKRSDSQPAGLEHMWRSPEDPPGPGASTVPASGLPRTGS
DPVILKTPVPLGSVADSLRASDGQLHAKAPTKPPRTPSLLLPDASGRPPTYCELVPRVLR
FQGPPPGHSCPESEVPWWEAEEEKEEDRCFARPQAEVSFCLPDTPSCLLGSQNRPLEPEV
LHTLRGLFLEHHPGSTALHLLLVDCQATGVLGVTKAQRGAMGVASGLELLTLPHGHRLRL
ELLERLETLALAGALAVLGCAGPLEERAAALRGLVELAVALRPGAVGDLPGLAAVMGALL
MPQVSRLERTWRHLRRSHTEAALAFEQELKPLMRSLNEGAGPSDPGEVALPHVAPAARLL
EGEELPGPLDESCERLLRTLHRARQTARDAPRFREAVARRLRG

>Pteropus vampyrus_SH2D3A(ENSPVAP_16894)
MQVPQDGEDFASQPWYHGPLSRQKAEALLRQDGDFLVRASESHGGHPVISCRWQGLALHF
EVLCVALRPRPGRPAALFQLEDERFPSLHALVHSYVSGQRPLTQATGAVASRPVTRQEPI
RCSFSEDTLLDSPARVKLLRGRKWSDSQPAGLELVGQSREGHSGPGASAVPTFALRRMGS
DPVLLKTSDPLGSIADSLWASDGQLHTKMPTKPPRTPPLVLPDASGRPPTYCELVLRVSS
ARGTPSGHSCPEPETPWWETQEEVEDERCFARPQAQVSFCPADNPSSLLGPQNRPLEPKV
LHILRGLFLEHHPASTACHLLLADCQATGLLGVTKAQRDAMGVASGLELLTLPHGHCLRS
ELLERHEALVLAGALAVLGCSGPLEERAAALRGLVELALELRPGAAGDLPGLAAVMGALL
MPQVSRLERTWRQLRRSHTEAALAFEQELKPLMRALDEGAGPCDPGEVALPHVAPAVRLL
EGEEILGPLDESCEQLLHVARDAPKFREAAARRLRGFRPNPELSEALTTGFMRRLLWGSR
GEGAPRAARLEKFQLVLSVLSHRLEPDH

>Takifugu rubripes_SH2D3A(ENSTRUP_35128)
MDALKKELEEELKLSSEDLKSHAWYHGPLGREAGEALLERDGDFLVRDSSSAPGDYVLTC
FWMNGPMHFKIIRVVLRPKQGYSRELFQFEEDRFDNVPALIRFHVGSRRPISQASSAVIF
HPITRTLPLRVIREQQAGAGSGKQAKSSKRRSLSTAHADMLQIINPLLRSGSQPANLENV
GRRPSLQSAQSDSNIRTGTILTTVTRAQDPGPAPISPVFRTGSEPLLSPQHTRPSLPGVG
VTLQGSDGQLHPRAPPKPLRISAVFPNAVIPPPIQRDEDPSSFYDELVVQYHSLCLSKTK
IPQAKQKGHVDRLRAEEKWQSRARLTETSFGFLEASSQLPVIPQKKMADKVEDCHFQKPQ
VETGSCFQLDRFDSLLLPQNNRPLEPSVLLALKELFNRSNANTTALHMLSVDCQVARITG
VTEEQKTLMGVESGLELVTLPHGQQLRQDLLERHHLISLGVAVDILGCTGTVSQRAAVLH
KIILLAQALKEHTHNLYSFSAVMKALEMHQITRLEMTWRALRQNHTEMAVLFEKTLKPFM
KLLNEGNDSVVDGPVAVPHLVPLLMAMEGDDPVENSERGCQLLYNILQSARNAAVRAQEY
QEHAHSLLTGWVPVPELLEAFQTEFALRLLWGQSGAAGDKRERYEKFDKVLSVLSNKLEP
VEHNPDTC

>Tetraodon nigroviridis_SH2D3A(ENSTNIP_11095)
LKKELEEELKLSSEDLSSHAWYHGPLRREAAEALLERNGDFLVRDSSSTPRDYVLTCFWM
NMPMHFKIIRVVLRPKKGYSRELFQFEEDRFDNIPALIRLYVGGRRPISQASGAVISHPI
TRTLPLRVIREQQAVPDSKGAGSDKEAKSSKRRSLSTADTLQVINPLLRSGEACRNAYKY
RSGSQPANLENVGRRPSLQSAQSDSNIRTGTPQITRAEEPGPVPMSPVFRTGSEPMLSPR
HTRPSLPGGGVTLRGSDGQLHPRAPPKPLRVSAVFPNAVIPPPLQRKEDPSSFYDELVVQ
YHSLCLYKQRGLPVPQARHKSHVDRLRAEEKWQSRARLTETSFGFLEASSQPPLIPQKTE
QKVEDWHFQKPHVELESCFQLDRFDSLLLPQNNRPLEPSVLLVLKELFNRSNANATALHM
LSVDCQVVRITQVTEEQKTIMGVESGLELITLPHGRQLRLDLLERHHLLALGVAVDILGC
TGTVSQRAAVLHKIILLAQALKEHAHDLYSFSAVMKALEMPQVARLEMTWRALRQNHTEM
AVLFEKTLKPFMNLLNEGDNAAFDGPVAVPHLVPLLMAMEGDDPVENSERGCQLLYNILQ
CARNTAVHAHDYQQHANSLLTGWVPVPELLEVFRTEFALRLLWGQSGAAGDKRERYEKFD
KVLTVLSNKLEPVEIRTTQA>Homo sapiens_SH2D3A(ENSP_245908)
MQVPQDGEDLAGQPWYHGLLSRQKAEALLQQNGDFLVRASGSRGGNPVISCRWRGSALHF
EVFRVALRPRPGRPTALFQLEDEQFPSIPALVHSYMTGRRPLSQATGAVVSRPVTWQGPL
RRSFSEDTLMDGPARIEPLRARKWSNSQPADLAHMGRSREDPAGMEASTMPISALPRTSS
DPVLLKAPAPLGTVADSLRASDGQLQAKAPTKPPRTPSFELPDASERPPTYCELVPRVPS
VQGTSPSQSCPEPEAPWWEAEEDEEEENRCFTRPQAEISFCPHDAPSCLLGPQNRPLEPQ
VLHTLRGLFLEHHPGSTALHLLLVDCQATGLLGVTRDQRGNMGVSSGLELLTLPHGHHLR
LELLERHQTLALAGALAVLGCSGPLEERAAALRGLVELALALRPGAAGDLPGLAAVMGAL
LMPQVSRLEHTWRQLRRSHTEAALAFEQELKPLMRALDEGAGPCDPGEVALPHVAPMVRL
LEGEEVAGPLDESCERLLRTLHGARHMVRDAPKFRKVAAQRLRGFRPNPELREALTTGFV
RRLLWGSRGAGAPRAERFEKFQRVLGVLSQRLEPDR

>Pan troglodytes_SH2D3A(ENSPTRP_17653)
MQVPQDGEDLAGQPWYHGLLSRQKAEALLQQDGDFLVRASGSRGGNPVISCCWRGSALHF
EVFRVALRPRPGRPTALFQLEDEQFPSIPALVHSYMTGRRPLSQATGAVVSRPVTWQGPL
RRSFSEDTLMDGPARIEPLRARKWSNSQPADLAHMGRSREDPPGMEASTMPISALPRTSS
DPVLLKAPAPLGTVADSLRASDGQLQAKAPTKPPRTPSFELPDASERPPTYCELVPRVPS
VQGTSPSQSCPEPEAPWWEAEEDEEEENRCFTRPQAEISFCPHDAPSCLLGPQNRPLEPQ
VLHTLRGLFLEHHPGSTALHLLLVDCQATGLLGVTRDQRGNMGVSSGLELLTLPHGHHLR
LELLERHQTLALAGALAVLGCSGPLEERAAALRGLVELALALRPGAAGDLPGLAAVMGAL
LMPQVSRLEHTWRQLRRSHTEAALAFEQELKPLMRALDEGAGPCDPGEVALPHVAPMVRL
LEGEEVAGPLDESCERLLRTLHGARHMVRDAPKFRKVAAQRLRGFRPNPELREALTTGFV
RRLLWGSRGAGAPRAERFEKFQRVLGVLSQRLEPDR

>Macaca mulatta_SH2D3A(ENSMMUP_11407)
EAFATPVSALPRTGSDPVLLKAPAPLGTVANSLRASDGQLQAKAPAKPPRTPSFELPDAS
ERPPTYCELVPRVPCVQGTSLSQSCPEPEAPWWEAEEDEEEENRCFTRPQAEISFCPPDT
PSCLLGPQNRPLEPQVLHTLRGLFLEHHPGSTALHLLLVDCQATGLLGVTRVQRDNMGVS
SGLELLTLPHGCRLRLELLERHETLALAGALAVLGCSGPLEERAAALRGLVELALALRPG
AAGDLPGLAAVMGALLMPQVSRLEHTWRQLRRSHTEAALAFEQELKPLMRALDEGVGPCD
PGEVALPHVAPTVRLLEGEEVAGPLDESCERLLRTLHGARHMARDAPKFRKVAAQRLRGF
RPNPELREALTTGFLRRLLWGSRGAGAPRAERFEKFQRVLGVLSQRLEPDS

>Callithrix jacchus_SH2D3A(ENSCJAP_30061)
MQVPQDGEDLAGQPWYHGPLSRQKAEALQQDGDFLVRASGSRGGHPVISCRWRGSALHFE
VFRVALRPRPGRPTALFQLEDEQFPSMPALVHSYLTGKRPLSQATGAVVSRPVTRPGPLR
RSFSEDTLMDGPARTEPLRVRKWSSSQPADLAHIGRSREDPPGMGASTMPVSALLRSGSE
PVLLKAPASLGTINNSLRGSDGQLQAKAPTKPPRTPSLELPDVPERPPTYCELVPRVPSV
QGTSPSQSRQETEVPWWEAEEDEEEENRCFTRPQAEIAFCPPDAPSCLLGPQNRPLEPQV
LRTLRDLFLEHHPGSTALHLLLVDCQATGLLGVTRDQRGNMGVSSGLELLTLPHGHRLRS
ELLERHETLTLAGALAVLGCSGPLEERAAAVRGLVELALALRPGAAGDLPGLAAVMGALL
MPQVSRLEHTWRHLRRSHTEAALAFEQELKPLMRALDEGAGPCDPGEVALPHVAPVVRLL
EGGEEVAGPLEESGERLLRTLHGARQMARLAPKFRKVAAQRLRGFRPNPELSEALTTGFL
RRLLWGSRGAGAPHAERFEKFQRVLGVLSLRLEPDR

>Canis familiaris_SH2D3A(ENSCAFP_27451)
MQVPQDGEDFASQPWYHGPLSRQKAEALLQQDGDFLVRASRSRGGHPVISCRWQGSALHF
EVLRVALRPRPGRPTALFQLEDERFPSLPSLVLSYVTGQRPLSQATGAVASRPVIRQGPI
RRSFSEDTLLESPARIELPRARKRSDSQPAGLEHMGLSGEDHSGPGASPVPTCALPRMGS
DPVLLKTPASLGSVVDGLRASDGQLHAKAPNKPPRTPSLVLHDASGRPPTYCELVPRVPS
AQETPTGHSGPETEASWWEANEEEEEEDRSFARPKAEVFFCPPNNLFCLLGPQNRPLEPK
VLSTLRDLFLEHHPGSTALHLLLVDCQATGLLGVTKAQRGAMGVTSGLELLTLPHGHRLR
LELLERHEALALAGALAVLGCSGPLEERAATLRGLVELALALRPGAAGDLPGLAAVMGAL
LMPQVSRLERTWRQLRRSHTQAALAFEQELKPLMRALDEGAGPCAPGEVALPHVVPAVRL
LEGQELPGPLDESCERLLRTLHRARLVARDAPQFREAAARRLRGFQPNPQLREALTTGFV
QRLLWGSQGVGAPHATRLEKFQRVLSALSQRLEPDV

>Felis catus_SH2D3A(ENSFCAP_19127)
MQVPQDGEDFASQPWYHGPLSRQKAEALLQQDGDFLVRASGSRGGHPVISCRWQGSALHF
EVLRVALRPRPGRPTALFQLEDERFPSLTSLVLSYVTGQRPLSQATGAVASRPVIRQGPI
RRSFSEDTLRGSPALTELPRTRKWSDSQPAGLEHMGRSREDHCGPEASAMPLCALPRTGS
DPVLLKTPAPLGSVADSLRASDGQLHAKAPTKPPRTPSLVLRDASGRPPTYCELVPRVPS
AQGTPPGHSSPETEAPWWEAEEEEEEESRSFARPQAEVSFCPPNNPSCLLGPQNRPLEPR
VLSTLRGLFLEHHPGSTALHLLLVDCQATGLLGVTKAQRGAMGVASGLELLTLPHGHRLR
LELLERHEALALAGALAVLGCAGPLEERAATLRGLVELALALGPGAAGDLPGLAAVMGAL
LMPQVSRLERTWRQLRRSHTEAALAFEQELKPLMRALDEGAGPCDPGEVALPHVVPAVRL
LEGEELPGPLDESCERLLRTLHRARQMAQDAPKFREAAARRLRGFHPNPQLREALTTGFV
QRLLWGSRGVGAPQAARLEKFQRVLSVLSQRLEPDG

>Bos taurus_SH2D3A(ENSBTAP_18405)
MQVPQDGEDFVGQPWYHGPLSRQKAEDLLQQDGDFLVRASKSRGGHPVISCRWRGSALHF
EVLRVALRPRPGRPTALFQLEDERFPSLPALVRSYVIGQRPLSQATGAVASRPVPRQGLI
RRSFSEDTLPDDPARTEPLRDRKRSDSQPAGLEHMWRSPEDPPGPGASTVPASGLPRTGS
DPVILKTPVPLGSVADSLRASDGQLHAKAPTKPPRTPSLLLPDASGRPPTYCELVPRVLR
FQGPPPGHSCPESEVPWWEAEEEKEEDRCFARPQAEVSFCLPDTPSCLLGSQNRPLEPEV
LHTLRGLFLEHHPGSTALHLLLVDCQATGVLGVTKAQRGAMGVASGLELLTLPHGHRLRL
ELLERLETLALAGALAVLGCAGPLEERAAALRGLVELAVALRPGAVGDLPGLAAVMGALL
MPQVSRLERTWRHLRRSHTEAALAFEQELKPLMRSLNEGAGPSDPGEVALPHVAPAARLL
EGEELPGPLDESCERLLRTLHRARQTARDAPRFREAVARRLRG

>Pteropus vampyrus_SH2D3A(ENSPVAP_16894)
MQVPQDGEDFASQPWYHGPLSRQKAEALLRQDGDFLVRASESHGGHPVISCRWQGLALHF
EVLCVALRPRPGRPAALFQLEDERFPSLHALVHSYVSGQRPLTQATGAVASRPVTRQEPI
RCSFSEDTLLDSPARVKLLRGRKWSDSQPAGLELVGQSREGHSGPGASAVPTFALRRMGS
DPVLLKTSDPLGSIADSLWASDGQLHTKMPTKPPRTPPLVLPDASGRPPTYCELVLRVSS
ARGTPSGHSCPEPETPWWETQEEVEDERCFARPQAQVSFCPADNPSSLLGPQNRPLEPKV
LHILRGLFLEHHPASTACHLLLADCQATGLLGVTKAQRDAMGVASGLELLTLPHGHCLRS
ELLERHEALVLAGALAVLGCSGPLEERAAALRGLVELALELRPGAAGDLPGLAAVMGALL
MPQVSRLERTWRQLRRSHTEAALAFEQELKPLMRALDEGAGPCDPGEVALPHVAPAVRLL
EGEEILGPLDESCEQLLHVARDAPKFREAAARRLRGFRPNPELSEALTTGFMRRLLWGSR
GEGAPRAARLEKFQLVLSVLSHRLEPDH

>Takifugu rubripes_SH2D3A(ENSTRUP_35128)
MDALKKELEEELKLSSEDLKSHAWYHGPLGREAGEALLERDGDFLVRDSSSAPGDYVLTC
FWMNGPMHFKIIRVVLRPKQGYSRELFQFEEDRFDNVPALIRFHVGSRRPISQASSAVIF
HPITRTLPLRVIREQQAGAGSGKQAKSSKRRSLSTAHADMLQIINPLLRSGSQPANLENV
GRRPSLQSAQSDSNIRTGTILTTVTRAQDPGPAPISPVFRTGSEPLLSPQHTRPSLPGVG
VTLQGSDGQLHPRAPPKPLRISAVFPNAVIPPPIQRDEDPSSFYDELVVQYHSLCLSKTK
IPQAKQKGHVDRLRAEEKWQSRARLTETSFGFLEASSQLPVIPQKKMADKVEDCHFQKPQ
VETGSCFQLDRFDSLLLPQNNRPLEPSVLLALKELFNRSNANTTALHMLSVDCQVARITG
VTEEQKTLMGVESGLELVTLPHGQQLRQDLLERHHLISLGVAVDILGCTGTVSQRAAVLH
KIILLAQALKEHTHNLYSFSAVMKALEMHQITRLEMTWRALRQNHTEMAVLFEKTLKPFM
KLLNEGNDSVVDGPVAVPHLVPLLMAMEGDDPVENSERGCQLLYNILQSARNAAVRAQEY
QEHAHSLLTGWVPVPELLEAFQTEFALRLLWGQSGAAGDKRERYEKFDKVLSVLSNKLEP
VEHNPDTC

>Tetraodon nigroviridis_SH2D3A(ENSTNIP_11095)
LKKELEEELKLSSEDLSSHAWYHGPLRREAAEALLERNGDFLVRDSSSTPRDYVLTCFWM
NMPMHFKIIRVVLRPKKGYSRELFQFEEDRFDNIPALIRLYVGGRRPISQASGAVISHPI
TRTLPLRVIREQQAVPDSKGAGSDKEAKSSKRRSLSTADTLQVINPLLRSGEACRNAYKY
RSGSQPANLENVGRRPSLQSAQSDSNIRTGTPQITRAEEPGPVPMSPVFRTGSEPMLSPR
HTRPSLPGGGVTLRGSDGQLHPRAPPKPLRVSAVFPNAVIPPPLQRKEDPSSFYDELVVQ
YHSLCLYKQRGLPVPQARHKSHVDRLRAEEKWQSRARLTETSFGFLEASSQPPLIPQKTE
QKVEDWHFQKPHVELESCFQLDRFDSLLLPQNNRPLEPSVLLVLKELFNRSNANATALHM
LSVDCQVVRITQVTEEQKTIMGVESGLELITLPHGRQLRLDLLERHHLLALGVAVDILGC
TGTVSQRAAVLHKIILLAQALKEHAHDLYSFSAVMKALEMPQVARLEMTWRALRQNHTEM
AVLFEKTLKPFMNLLNEGDNAAFDGPVAVPHLVPLLMAMEGDDPVENSERGCQLLYNILQ
CARNTAVHAHDYQQHANSLLTGWVPVPELLEVFRTEFALRLLWGQSGAAGDKRERYEKFD
KVLTVLSNKLEPVEIRTTQA

>Homo sapiens_BCAR3(ENSP_260502)
MAAGKFASLPRNMPVNHQFPLASSMDLLSSRSPLAEHRPDAYQDVSIHGTLPRKKKGPPP
IRSCDDFSHMGTLPHSKSPRQNSPVTQDGIQESPWQDRHGETFTFRDPHLLDPTVEYVKF
SKERHIMDRTPEKLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLVQRDGDFLVRDSL
SSPGNFVLTCQWKNLAQHFKINRTVLRLSEAYSRVQYQFEMESFDSIPGLVRCYVGNRRP
ISQQSGAIIFQPINRTVPLRCLEEHYGTSPGQAREGSLTKGRPDVAKRLSLTMGGVQARE
QNLPRGNLLRNKEKSGSQPACLDHMQDRRALSLKAHQSESYLPIGCKLPPQSSGVDTSPC
PNSPVFRTGSEPALSPAVVRRVSSDARAGEALRGSDSQLCPKPPPKPCKVPFLKVPSSPS
AWLNSEANYCELNPAFATGCGRGAKLPSCAQGSHTELLTAKQNEAPGPRNSGVNYLILDD
DDRERPWEPAAAQMEKGQWDKGEFVTPLLETVSSFRPNEFESKFLPPENKPLETAMLKRA
KELFTNNDPKVIAQHVLSMDCRVARILGVSEEMRRNMGVSSGLELITLPHGHQLRLDIIE
RHNTMAIGIAVDILGCTGTLEDRAATLSKIIQVAVELKDSMGDLYSFSALMKALEMPQIT
RLEKTWTALRHQYTQTAILYEKQLKPFSKLLHEGRESTCVPPNNVSVPLLMPLVTLMERQ
AVTFEGTDMWEKNDQSCEIMLNHLATARFMAEAADSYRMNAERILAGFQPDEEMNEICKT
EFQMRLLWGSKGAQVNQTERYEKFNQILTALSRKLEPPPVKQAEL

>Pan troglodytes_BCAR3(ENSPTRP_1675)
MAAGKFASLPRNMPVNHQFPLASSMDLLSSRSPLAEHHPDAYQDVSIHGTLPRKKKGPPP
IRSCDDFSHMGTLPHSKSPRQNSPVTQDGIQESPWQDRHGETFTFRDPHLLDPTVEYVKF
SKERHIMDRTPEKLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLVQRDGDFLVRDSL
SSPGNFVLTCQWKNLAQHFKISRTVLRLSEAYSRVQYQFEMESFDSIPGLVRCYVGNRRP
ISQQSGAIIFQPINRTVPLRCLEERYGTSPGQAREGSLTEGRPDVAKRLSLTMGGVQARE
QNLPRGNLLRNKEKSGSQPACLDHMQDRRALSLKAHQSESYLPIGCKLPPQSSGVDTSPC
PNSPVFRTGSEPALSPAVVRRVSSDARAGEALRGSDSQLCPKPPPKPCKVPFLKVPSSPS
AWLNSEANYCELNPAFATGCGRGAKLPSCAQGSHTELLTAKQNGAPGPRNSGVNYLILDD
DDRERPWEPAAAQMEKGQWDKGEFVTPLLETVSSFRPNEFESKFLPPENKPLETAMLKRA
KELFTNNDPKVIAQHVLSMDCRVARILEVSEEMRRNMGVSSGLELITLPHGHQLRLDIIE
RHNTMAIGIAVDILGCTGTLEDRAATLSKIIQVAVELKDSMGDLYSFSALMKALEMPQIT
RLEKTWTALRHQYTQTAILYEKQLKPFSKLLHEGRESTCVPPNNVSVPLLMPLVTLMERQ
AVTFEGTDMWEKNDQSCEIMLNHLATARFMAEAADSYRMNAERILAGFQPDEEMNEICKT
EFQMRLLWGSKGAQVNQTDRYEKFNQILTALSRKLEPPPAKQAEL

>Macaca mulatta_BCAR3(ENSMMUP_20954)
MAAGKFASLPRNMPVNHQFPLASSMDLLSSKSPLTEHRPDAYQDVSIHGTLPRKKKGPPP
IRSCDDFSHMGTLPHSKSPRQNSPVTQDSIQESPWQDRHCETFTFRDPHLLDPTLEYVKF
SKERHIMDRTPEKLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLVQRDGDFLVRDSL
SSPGNFVLTCQWKNLAQHFKINRTVLRLSEAYSRVQYQFEMESFDSIPGLVRCYVGNRRP
ISQQSGAIIFQPINRTVPLRCLEERYGISPGQAREGSLTEGRPDVTKRLSLTMGGVQARE
QNLPRGNLLRNKEKSGSQPACLDHMQDRRALSLKAHQSESYLPIGCKLPPQSSGVDTSPC
PNSPVFRTGSEPALSPAVVRRVSSDARAGEALRGSDSQLCPKPPPKPCKVPFLKAPSSPS
AWLNSEANYCELNPAFATGRGAKLPLCAQGSPTELLTAKQNGALGPRNSGINYLILDDDD
RERPWEPAAAQTEKGQWDKGEFVAPLLETVSSFRPNDFESKFLPPENKPLETAMLKRAKE
LFTNNDPKVIAQHILSMDCRVARILEVSEEMRRNMGVSSGLELITLPHGHQLRLDIIERH
STMAIGIAVYILGCTGTLEDRAATLSKVIQVAVELKDSMGDLYSFSALMKALEMPQITRL
EKTWTALRHQYTQTAILYEKQLKPFSKILHEGRESTCVPPNNVSVPLLMPLVTLMERQAV
IFEGTDMWEKNDQSCEIMLNHLATARLMAEATDSYRINAERILAGFQPDEEMNEICKTEF
QMRLLWGSKGAQVNQAERYEKFNQILTALSRKLEPPPVKQAEL

>Callithrix jacchus_BCAR3(ENSCJAP_46232)
MAAGKFASLPRNMPVNHQFPLASSMDLLSSKSSLTEHRTDAYQDVSIHSTLPRKKKGPPP
IRSCDDFSHMGTLPHSKSPRQNSPLTQDGIQESPRQDRQGETFTFRDPHLLDPTLEYVKF
SKERHMMDRTPERLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLVQRDGDFLVRDSL
SSPGNFVLTCQWKNLAQHFKINRTVLRLSEAYSRVQYQFEMESFDSIPGLVRCYVGNRRP
ISQHSGAIIFQPINRTVPLRCLEERYGTSSGRAQEGSLTEGRPDVAKRLSLTMGGVQTRE
QNLPRGNLLRNKEKSGSQPACLDHMQDRRALSLKAHQSESYLPIGCKLPPQSSGVDTSPC
PNSPVFRTGSEPALSPAVVRRVSSDARAGEALRGSDSQLCPKPPPKPCKVPLLKAPSSPS
AWLNSEANYCELNPAFATGCSRAAKLPLCAQGSRTELLTARQNGVPGPRNSGINYLILDG
DDRERPWEPVATQMEEGQWDKGKFVTPLLETVSSFRPNDFESKLLPPENKPLETAMLKRA
KEVFTNSNPKIIAQHILSMDCKVARILEVSEEMKRNMGVSSGLELITLPHGHQLRLDIIE
RHNTMAMGIAVDILGCTSTLDERAATLSKIIQVAVELKDSMGDLYSFSALMKALEMPQIT
RLEKMWTALRHQYTQTAILYEKQLKPFSKILHEGRESTCVPPSNVSVPLLMPLVTLMERQ
AVTFEGTDMWEKNDQSCEIMLNHLATARFMAQTADSYRMNAEMNLAGFQPDEEMNEICKT
EFQMRLLWGSKGAQVNQTERYEKFNQILTALSRKLEPPPVKQAEL

>Mus musculus_BCAR3(ENSMUSP_29766)
MAAGKFASLPRNMPVNHQFPLASSMDLLSSKSPLAERRTDAYQDVSIHGTLPRKKKGPPS
IRSCDNAGHSKSPRQSSPLTQDIIQENPLQDRKGENFIFRDPYLLDPTLEYVKFSKERHI
MDRTPERLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLVQRDGDFLVRDSLSSPGNF
VLTCQWKNLAQHFKINRTVLRLSEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPISQQSG
AIIFQPINRTVPLWCLEERYGTSPGRGREGSLAEGRPDVVKRLSLTTGSSIQAREHSLPR
GNLLRNKEKSGSQPACLDHVQDRKALTLKAHQSESHLPIGCKLPPQSPSMDTSPCPSSPV
FRTGSEPTLSPALVRRFSSDARTGEALRGSDSQLCPKPPPKPCKVPFLKTPPSPSPWLTS
EANYCELNPAFAVGCDRGAKLPMQAHDSHEMLLTAKQNGPSGPRNSGINYMILDGDDQAR
HWDPLAVQTDEGQEDKTKFVPPLMETVSSFRPNDFESKLLPPENKPLETAMLKHAKELFT
NHDARVIAQHMLSVDCKVARILEVSEDRKRSMGVSSGLELITLPHGRQLRLDIIERHNTM
AIGIAVDILGCTGTLENRAGTLNKIIQVAVELKDAMGDLYAFSAIMKALEMPQITRLEKT
WTALRHHYTQTAILYEKQLKPFSKILHEGRESTYVPASNVSVPLLMPLVTLMERQAVTFE
GTDMWENNDESCEILLNHLATARFMAEASESYRMNAERILADFQPDEEMTEILRTEFQMR
LLWGSKGAEVNQNERYDKFNQILTALSRKLEPPSGKQAEL

>Rattus norvegicus_BCAR3(ENSRNOP_62880)
MAAGKFASLPRHMPVNHQFPLASSMDLLSSKSPLAEHRTEAYPDVSIHGTLPRKKKGPPP
IRSCDSASHMGTLPHSKSPRQSSPLTQDLILEKPLPDWKGDSFAFRDPYLLDPTLEYVKF
SKERHIMDRTPERLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLVQRDGDFLVRDSL
SSPGNFVLTCQWKNLAQHFKINRTVLRLSEAYSRVQYQFEMESFDSIPGLVRCYVGNRRP
ISQQSGAIIFQPINRTVPLWCLEERYGTSPGRGREGSFAEGRPDVVKRLSLTTGGIQARD
HSLPRGNLLRNKDKSGSQPACLDHVQDRKAATLKAHQSESHLPIGCKLPPQSPSVDTSPC
PNSPVFRTGSEPTLSPALVRRFSSDARAGEALRGSDSQLCPKPPPKPCKVPFLKVPPSPS
PWLNSEANYCELNPAFAVGCDRGAKLLSQALDSHEMLLTAKQNGASGPRNSGINYSILDG
DDQGRHWDPLAVQTDEGQEDETKFVPPVMETVSSFRPNDFESKLLPPENKPLETAMLKHA
KELFTNHDARVIAQHMLSVDCKVARILEVSEDMKRSMGVSSGLELITLPHGRQLRLDIIE
RHNTMAIGIAVDILGCTGTLENRAGTLNKIIQVAMELKDTMGDLYSFSAIMKALEMPQIT
RLEKTWTALRHHYTQTAILYEKQLKPFSKILHEGRESTYVPASSVSVPLLMPLVTLMERQ
AVTFEGTDMWEKNDESCEIMLSHLATARFMAEASESYRMNAERVLADFQPDEEMTEILKT
EFQMRLLWGSKGAEVNQNERYDKFNQILTALSRKLEPPSGKQAEL

>Oryctolagus cuniculus_BCAR3(ENSOCUP_13264)
MLALCRKQFEEKAIDCFNNFCDFLRQTELLPPRHTWILKAAKFRFLGPVPNIKELRVMAA
GKFASLPRNMPVSHPSPLASSMDLLSSTSPLAEHHADAYPDASIHGTLPRKKKGPPPIRS
CDSFSHMGTLPHAKSPRQSSPRTQDVIRESPLQDWKGETFTFRDLHLLDSTLDYVKFSKD
RHVMDRTPERLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLMQRDGDFLVRDSLSSP
GNFVLTCQWKNLAQHFKITRTVLRLSEAYSRVQYQFETESFDSIPGLVRCYVGNRRPISQ
QSGAIIFQPINRTVPLRCLEERYGTTPGRARDSSLAHGRPDVTRRLSLSPGSVQAREQSL
PRGNLLRNKEKSGSQPACLDHMQDRRALSLKAHQSESYLPIGCKLPPQPPGVDTSPSPNS
PVFRTGSEPTLSPAVVRRVSADPRSGEALRGSDSQLCPKPPPKPCKAPVLKAPLSPPTQL
SAEANYCELNPACAAGGDHGVRPPLCALGSHVQLPTARLSEAPGSRNSGTSYLILDGDDG
ARPWEPPAAQMEEGTCKEDTGEFVAPLLETVSSFRPNDFESKLLPPENKPLETAMLKRAK
ELFASHHPRVIAQHLLHTDCKVARILEVSEETRRNMGVSSGLELLTLPHGRQLRLDIIER
HNTMAIGVAVDILGCTGSLEDRAATLNRIIQVAAELKDAVGDLYSFSAIMKALEMPQITR
LEKTWTALRHQYTQTAILYEKQLKPFSKVLHEGREPTCVPPCSVSVPLLMPLVTLMERQA
VTFEGTDLWEKHDQSCEIMLNHLAAARLMAQAADSYRANAERMLAGFQPDEEMSEVFKTE
FQMRLLWGSKGAEVNQTERYEKFSQILTALSRKLEPPPAKQAEL

>Canis familiaris_BCAR3(ENSCAFP_29839)
MAAGKFVNLPRNMPVNHQFPLASSMDLLSSKSPPAEHHTDAYQDVSIHGTLPRKKKGPPP
IRSCDNFSHMGTLPHSKSPRQSSPLTSAIIQEHPLQDWKGETFTFRDQHLLDPTLEYVKF
SKDRHVMDRTPERLKKELEEELLLSGEDLRSHAWYHGRIPRQVSENLVQRDGDFLVRDSL
SSPGNFVLTCQWKNLAQHFKIHRTVLRLSEAYSRVQYQFETESFDSIPGLVRCYVGNRRP
ISQQSGAIIFQPINRTVPLRCLEERYGASPGRRPDVGKRLSLTMGGVQAREQSSPKGNLL
RNKEKSGSQPACLDHMQDRRALSLKAHQSESYLPLGCKLSSRSPSVDTSPRPNSPVFRTG
SEPTLSPALVRRVSSDARAGEALRGSDSQLCPKPPPKPCKAPLLQPPPSPSTWLNSEANY
CELNPAFATGGDRGARPPLCAHDSYVELLTAKQNGVLGPRHSGTNYLILDDDGAGPGEAP
ATQMDQGQQEDEGEFVLPRLETASSFRPNDFESKLLPAENKPLEMAMLKRVKELFTSKDP
KAIAQHMLSTDCMVARILAVSEETRRNMGVSSGLELLTLPYGHQLRLDIIERHNTMAIGI
AVDILGCTSTLEDRAATLNRIIQVAVELKDSMGDLYSFSAIMKALEMPQITRLEKTWTAL
RHQYTQTAILYEKQLKPFSKMLHEGRESMCVPPNKISVPLLLPLVTLMERQAVTFEGTDM
WEKNDESCEIMLNHLATGRLMAETADSYRMNAERILEGFQPDEEMSEIFKTEFQMRLLWG
SKGAQVNQTERYEKFNQILTALSRKLEPPPVKQAEL

>Felis catus_BCAR3(ENSFCAP_5134)
MHCSQFSYLPFSLFRDQHLLDPTLEYVKFSKERHVMDRTPERLKKELEEELLLSGEDLRS
HAWYHGRIPRQVSENLVQRDGDFLVRDSLSSPGNFVLTCQWKNLAQHFKIHRTVLRLSEA
YSRVQYQFETESFDSIPGLVRCYVGNRRPISQQSGAIIFQPINRTVPLRCLEERYGASPG
RAREGSLAEGRSDVGKRLSLTMGGLQAREQSSTRGNLLRNKEKSGSQPACLDHMQDRRAL
SLKAHQSESYLPIGCKLPPQSPGVDTSPCPNSPVFRTGSEPTLSPAVVRRVSSDARAGEA
LRGSDSQLCPKPPPKPCKAPVLKAPPSPSTWLNSEANYCELNPGFAAGCDRGTRPPLCAQ
DSYVELLTAKQNGAPGPRNSGINYLTLDDDVGAGPWEAPATQKDQGQEDEVEFVPPRLET
ASSFRPNDFESKLLPPENKPLETAMLKRAKELFTNNDPKVIAQHMLSMDCVVARILEVSE
EMRKNMGVSSGLELITLPYGHQLRLDIIERHNTMAIGIAVDILGCTGSLEDRAATLNRII
QVAVELKDSMGDLYSFSAIMKALEMPQITRLEKTWTALRHQYTQTAILYEKQLKPFSKIL
HEGRESTCVPPNKISVPLLMPLVTLMERQEVTFEGTDMWEKNDESCEIMLNHLATARLMA
EAADSYRMNAERILEGFQPDEEMSEIFKTEFQMRLLWGSKGAQVNQTERYEKFNQILTAL
SRKLEPPPVKQAEL

>Bos taurus_BCAR3(ENSBTAP_4211)
MAAGKFASLPRNMPVNHQFPLASSMDLLSSKSPLVERRADAYQDVSIHGTLPRKKKGPPP
IRSCDNFSHVGTLPHSRSPRHHSPLIQDVIQEQPLQDWKGEAFTFRDQHLLDPTLEYVKF
SKERHVMDRTPERLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLMQRDGDFLVRDSL
SSPGDFVLTCQWKNLPQHFKIRRTVVRLSEAYSRVQYQFEMESFDSIPGLVRCYVGNRRP
ISQQSGAIIFQPVNRTVPLRCLEERYGASSPDRAHEGSLTEGRPDAAKRLSLTVGGTQAR
EQGLPRGNLLRNKEKSGSQPACLDHMQDRRALSLKAHQSESYLPIGGKLTPQSPSVGTSP
CPNSPVFRTGSEPTLSPAVVRRVSSDARPGEALRGSDSQLCPKPPPKPCKAPLLKAPPSP
SIWLNSEANYCELNPALAASYDGASRLPFCAQDSYVELLTAKQNGGLGTRNSDTSYLILD
DDDRTRPWKPPPAPGDTVGEDQDTFVMPLLETTSSFKPNDFESKLLPPENKPLETSMLKR
AKELFTNSDPKVIAQHLLSVDCKVARILEVSEEMRKNMGVNSGLELITLPYGHQLRLDII
ERHNTMAIGIAVDILGCTGSLEDRAATLNKIIQVAVELKDSMGDLYSFSAIMKALEMPQI
TRLEKTWTALRHQYTQTAILYEKQLKPFSKVLHEGRESTCVPPNNVSVPLLMPLVTLMER
EAVTFEGTDMWEKNDESCEIMLNHLATARLMAEAADSYRMNAEKILAGFQPDEEMSEVFK
TEFQMRLLWGSKGAQVNQTERYEKFNQILTALSRKLEPPPVKQMEF

>Gallus gallus_BCAR3(ENSGALP_9323)
MIAAGKFSSLPRNVPVNVNHQFSLASSMDLLTTKPSLTEHRSDSFQDISIHGTLPRKKKG
TVKVRACDMFSHVGMLPYTRTQRQQPPFVQDVIEEYPLQNGKSNKLHTRDQNIPDPTLEY
VKFSKERQVMDNSPEKLKKELEEELQLSSEDLRSHAWYHGRIPRQVAEDLVQRDGDFLIR
DSLSCPGNFVLTCQWKNTSQHFKINRTILRLSEAYCRVQYQFELESFDSIPGLVRYYVGN
RTPISKQSGAIIFQPINRTVPLRCLEEKYGVIPDRQKEQSIPEGKTEAAKRLSLGISSMQ
SQEQSIPRGNLLRNKEKSGSQPASLDHVLDKRFPLKTHQSESYLLIGSRHSSRLPEADAD
SCPSSPAFRTGSEPSLSPTVVQKVTYDSQVGEALRGSDSQLYPKPPPKPSKATLLKTTDS
PMASHSSEGHYCELSLVRDSAATEHLCQKNSYVEHLTQKERGRQCFRNSETSYLILDDDH
TVNSAGPLDVSTETAEENNVFSAPLFETSSSFKPNDFESKLLPSENKPLETSMLRKIKEL
FTKNNPKVIAQHILRMDCKVARILEVSEEMRRIMGVNSGLELITLPYGHQLRLDLIERHN
TMAIGIAVDILGCTGNLEDRAATLNKIIQVAVELKDSLGDLYAFSAIMKALEMPQVSRLE
QTWTSLRHHYTQTAIMYEKQLKPFSKALHEGQEMVSVPQNLTLPLLMPLVTLMERQAVIF
EGMDLWESSDQSCEIMFKHLTTARQIAQNAEMYSLTAQRMLEGFQPDEEMSEIFKTEFQM
RLLWGSKGAQVNQNERYEKFSQILTALSRKLEPPPVKQVEQLSI

>Taeniopygia guttata_BCAR3(ENSTGUP_6057)
MIAAGKFSSLPRNSPVNHQFSLASSMDLLTTKPSPIEHHSNSFQGISIHGTLPRKKKGTI
PSRSCDMFSHVGALPYTRAWQQPPFVQDVIEEYPPDNGKSSELHARDKNILDPTLEYVKF
SRERQVMDKSPEKLKKELEEELQLSSEDLRSHAWYHGRIPRQVAEGLVQRDGDFLIRDSL
SSPGNFVLTCQWKNTPQHFKIIKTVLRLNEAYCRVQYQFELESFDTVPGLVRYYVGNRTP
ISKQSGAIIFQPVNRTVPLRCLEEKYSVTPVQQKEPRTPEGKMESAKRLSLGISSMQYPD
QSMPRGNLLRNKEKSGSQPASLDHVLEKRFPLKAHQSESYLLIGSRHPSRLPEADANSCP
SSPAFRTGSEPSLSPTVVQKVTSESQLGEALRGSDGQLCPKPPPKPSKAPLMKLPDSPLA
SHSSEGHYCELNPARHPTAAKQCLCQKNSYVEHLTQKERATFRNSETSYLIIDDDPTMHP
ADPLEAQMAEEDSIFSAPVYETVSSFKPNDFESKLLPPENKPLETSMLRRVKELFTNNNP
KIIAQHILRMDCKVARIVEVSEEMRRNMGGNSGLELITLPYGHQLRLDLIERHNTMAIGI
AVDILGCTGNVEDRAATLNRIIQVALELKESLGDLYGFSAIMKALEMPQVSRLEQTWTAL
RHCYTQTAIMYEKQLKPSCKALHEGQDDMCFAPQNNVTVPLLMPLVTLMERQAVVFEGME
LWESSDQSGEIMLRHLGTARLIAQHAETFRLTAEQLLQGFQPDEELSEIFKTEFQMRLLW
GSKGAQVNQSERYEKFNRILTALSRKLEPPPVKLVEQ

>Anolis carolinensis_BCAR3(ENSACAP_5316)
MKHISISSWLSQLGLPEYGTLFDQQYDGVEDLLHLTEAELKRMGVKNQIHRTHIISNISL
LQEAERKQELRMIAAGKFASLPRNMQMSHEFSLASSMDLLTSKPSLAADHRSGICQDVSI
HGTLPRKKRGPIPVGSSDPLHHMGTSPYCKGLRTQGPSIQNIIEEYPQKNKKNDNFFSRD
QNVADPTIEYVKFSKERQVMERQVTMDSSPEKLKKELEEELQMSSEDLRSHAWYHGRIPR
QVAESLIQRDGDFLIRDSLSSPGNFVLTCQWKNISQHFKINKTILRLNEAYCRVQYCFED
ESFDSIPGLVRCYVGNRRPISKQSGAIIFQPINRTVPLRCLEEKYGISPGMQREGSIPEG
QVDTPKRLSLNMCNRLAREQNSVRGNLLRNKEKSGSHPACLDHVQEKRFPLKAHQSESFL
PIGSRHLSQGTEAETSPCRKSPAFRTGSEPALSPLMFRRFASELQINDVLRGSDSQLYPK
PPPKPSKVPFLRPSHGSEVLYCELNAALPADCRISKQSLCQKNNFVDYLTTKENGTHPEP
NYLILDNRDSFLSSVDPLTAQTEMSNESDVFVAPVLEMVSSFQPNHFESKLLPSENKPLE
TAMLKKVKEFFTNNSAKTIAHHILKMDCKVARILEVSEEMRRTMGVKSGLELITLPYGHQ
LRLDIIERHNTMAIGIAVDILGCTGNLEERVTTLNRIIQVAVELKESMGDLYAFSAVMKA
LEMPQVTRLEQTWTMLRHCYTQTAIMYEKQLKPFCKALHEGREIASVPQNIVTVPLLMPL
INLLERQTVVFDGMDVWENTDQSCEIMLKHLATARLIAQNASLYSRNAERILAGFQPDNE
MKEIFKTEFQMRLLWGSKGAQVNQSERYEKFNQILTALSRKLESPQIKQNEL

>Pelodiscus sinensis_BCAR3(ENSPSIP_9227)
MIAAGKLASLPRNMQVNHQFSLASSMDLLSSKPPLAEHHLDSYQDISIHGTLPRKKKGAI
PIRSCDMFSHMGTLPFPKTHRQQSPLIQDVLEKCSLQDRKSEKHQFRDQNILDPAMEYVK
FSKERQVMDSTPEKLKKELEEELQLSSEDLRSHAWYHGRIPRQVAESLVQRDGDFLIRDS
LSSPGNFVLTCQWKNISQHFKINRTILRLNEAYCRVQYQFELESFDSIPGLVRCYVGNRR
PVSKQSGAIIFQPINRTVPLRCLEEKYGVSPVRQRECNITEGKTEIARRLSLSICSVQPQ
EHSLTRGNLLRNKEKSGSQPASLDHVQEKRFHLKTHQSESYLPAGLRHPFQLPEVDTNPR
SNSPTFRTGSEPTLSPTVGQRVASELPVGEALRGSDSQLCPKPPPKPNKVPFLRQPQSPL
AWHSSEAHYCELNPATSIDCEATQQPLSQKSSYVEHLIAKENGLLSFRNSEESYLIHEDD
ALLSSMDPLALRTEMAEEASVFVAPVLETESSFKPNDFESKLLPPENKPLETPMLKKVKE
LFTNSNPKIIAQHMLRMDCKVARILEVSEELRRSMGVSSGLEFITLPYGHQLRLDIIERH
NTMAIGIAVDILGCTGNLEERAATLNRIIQVAVELKDSLGDLYAFSAVMKALEMPQIARL
EQTWTTLRHHYTQTAIMYEKQLKPFSKALQEGGETICVPQNNITVPLLMPWVTLMERQFV
IFDGLDLWEYTDQSCEIMLKHLATARFIAQNADMYRMTAERKLEGFQPDDEMSEIFKTEF
QMRLLWGSKGAQVNQRDKSLIFKLIMSLQFKFSPNLLCSPLVK

>Xenopus tropicalis_BCAR3(ENSXETP_18036)
MAAGKFASYHRNVQMNHQFPLVSSMDLLGSKSALGERRSDSFQNVCIHGTLPRKKKERVP
IKSSDVFCHLGTLPHSKSHRLPNPVMQDIKEEYPFQERRTGIFNMREYYLDPSMEYVKFS
KDRYIMDGGTPDKLKKELEEELKLNSEDLRSHAWYHGRIPRQVSENLVKRDGDFLIRDSL
SSPGNFVLTCQWKNLSQHFKINKVVIRLNEAYCRIQYQLEHESFDSMPALVRYYVGNRKA
VSQQSGAIIFQPINRTVPLRCIEEKYGTSPVRRLELGPLEAKAEVPKRLSLNFGQGVSQE
QSLARGNLLRNKDKSGSQPACLDNMREKRRPLKAHQSESYLPLGSRHPCLSQGMDVKVSP
KAHVFRTGSEPALSPTEIRRFSNEAHPAEALRGSDSQLCPRPPPKPSKAPSIKQSHSPLV
WQSSEANYCELHPTPPEDCAWSDSYSSRNSYIEDQRTDDIESLSFSNSELSFPALDDSIS
QCSATNFCGNVEDNEFNRPVYETVSSFCPNDFQSVLLTAENKPLETALLRRAKELFTNND
PKTIAKHILRMDCKVARILDVTPEVEKMMGVSSGLELIILPFGHQLRLDLMERHTTMAIG
IAVDILGCTGNLEERVATLHKIIQLAVEVKALGDYFAFSAIMKALDMPQITRLEQTWTML
RHQYTHTAITYEKQLKPFSKYLHEGEALDTQEDLTVPLVMPLVALLERQSVIFEGMDFWE
NHDRGCEIMFNHLQTARQVAQYASVYRKNAERILEGFKPDELMSEIFKTEFQMRLLWGSK
GALLKQSERYHKFGQILTALSRKLEPPS

>Danio rerio_BCAR3(ENSDARP_104233)
MKHMSISKWLSQLGLPQYCILFDEEYDGVEDLLHLTEMDLLGLGVQSRLHRIHILSSIQV
LRERETKRELRMMAEGRFSSLPRNMHVGRQCPLASSMDLLSSRPELSEMPVSGYQGISIH
GTLPRKKKTTTGSPVKQWEVNGNVGSLAAPYPGRHRLPPSPLIHNIIEEHQTFCSDRKQS
RNSAGMDPTMEYVKFSRDKYILDGPPEKLRRELEEELKLSSEEPRSHAWYHGAIPRQVAE
NLVQRDGDFLIRDSLSSPGNYVLTCQWKNSPQHFKINKRVVAMNEAYSRVQYLFEKEGFD
SIPALVRYYVGNREPVSEVIGAIIFQPINRALPLRCLEEKYGVGSIRVEAGYLERKSLTS
KRLSLNIMNGHGQDHTLSRGNLLSNKDKCGSQPACLNHVQERRRPLKTHQSESFLPIGSR
PQAQVQHMEHQPCPKSPVFRTGSEPALSPTVPRRMAFDTLPGEAIRGSDSQLCPKPPPKP
SKVPTVRVPCIPALKTLVVPPVPPVKPHKHRPSLQQQQSGSPEMSYCELSPCSPADWEKM
NSLQANGYVERLKTDGSIKLDRSSYHNAIEALDNDSEEDTEEDADKEQNGKKAFQKPVFE
TESAFRPANVNFRLLPKENKPLEMTVLKKAKELLVSQDPKTIAKHILQADCQVARILNVS
EEVKGQMGVSSGLELVTLPHGRQLRLDLIERHNTMAIGVAVDILGCTGSLEERAATLNRI
ILVALELKDSMGDLYAFSSIMKALDMPQITRLDHTWTSLRRKYTQTAIIYEKSLKPFYKG
LYEGGAEIPLSNASVPLLMPLLTLMERPAVTFEGMDVWENTDQGCEIMFRHLEGARAVAR
NADTYTCNAQRILQDFQPHEDMLEILRTDFQLRLLWGSRGAAVEQTERYDKFKLILTALS
RKLEPAVKHTEL

>Takifugu rubripes_BCAR3(ENSTRUP_16410)
MSERCTLKTLTATLCCFYQKSSVITAKFSRDQFILECPSEKLRKELEEELKMDCEELRSH
AWYHGAIPRQVAETLVQRDGDFLIRDSLSSPGSYVLTSQWRNTAQHFKINKKVVTLNEAY
TRVEFRLDREGFDNVPALIRYYVGNRKPVSPVVGAIIFQPINRVLPLRCLEEKYGVSNNH
RERLMVQERRSQKRLSLNITNGHAHDGNLSSPRTKDRCGSQPASLNQVHDRRRPLKAHQS
ESYLPLGKRAPPHPLADSVPLSPSHKSPVFRTGSEPVLSPSVPRRSAELLSGQPIRGSDS
QLCPKPPPKPSKVLLSRLCPPADPPSLNAPQLDSSCAETPALPRRTGVDLQVPLCGHVER
LRREEVGEGEAVGRRGLDRSSYHHASAPLEYTSEEEEEDRKRKTLGFLRPIVETESTFRP
ADFGSRLLPPENKPLEMLVLKRAKELLLSHDHQSIARHLLKADCQVARIIGVTPELKSQM
GVASGLELVTLPHGRQLRLDLMERHHTMAIGVAVDILGCTGSVDERATTLNRIILVALEL
KDAVGDLFAFTALMKALDLPQISRLEETWTTLRRNYTQTAISYEKTLKPFFKNLYEGTAS
CPPTVCVPVLLPLLTLMERSSVMSEGAELWETNDQGCDIMLRHLEAARGVAHNTWSYAQN
AEKMLQEFRCDDELLEVFKTDFQLRLLWGSRGACVNQSDRYNKFNLILTALSRKLEPPPK
TQTVI

>Gasterosteus aculeatus_BCAR3(ENSGACP_7942)
MSEGCSLKTLTAALCCFYHKNSVMTAKFSRDQFIVDCPSEKLRKELEEELKMNCEEPRSH
AWYHGAIPRQVAEYLVQRDGDFLIRDSLSSPGCYVLTCQWRNAAQHFKINKKVVMLNEAY
SRVEYRLEREGFDNVPALIRYYVGNRKSVSQVVGAIIFQPINRGLPLRCLEEKYGLSSHR
RDALMAQERRSRKRLSLNVTNGHAQDDARGAQNGARGRGLRFKDRCGSQPASLNQVPERR
RPLQAHQSESYLPLGSKPQRSPDPLLPSPSPKSPVFRTGSEPVLSPSVPRRPAELLAGQA
IRGSDSQLCPKPPPKPSKVPLARPPAPPPGAPGLTHATSGSNAPALASACVQTLASPRSS
EGINSEIVYSASAGPPVPPVKPLKFLHQLRPEDTRGFSTSALSPTENGWKRSRFQRPVEE
TESAFQPAQFGSRLLPPENKPLETVVLKRAKELLLSHDHHSIARHLLLADCQVARTVGVT
PEVKGQMGVSSGLELVTLPHGRQLRLDLMERHHTMAIGVAVDILGCTGSVDERASTLNRI
ILVALELKDAVGDLFAFTALMKALDLPQISRLEETWTTLRRTYTQTAISYEKTLKPFYKN
LYEGTASSPAVVCVPLLLPLLTLMERPSITPEGAELWETSDQGCDIMLRHLEDARDVAHN
AQRYTINSQMILEGFPCDEDLLEVFKTDFQLRLLWGSRGASVNQSDRYNKFNLILTALSR
KLEPPPNTQIVI

>Oryzias latipes_BCAR3(ENSORLP_14954)
MSERCNLKALTAALCCFNHKNSVISGKFSRDQFILDCSSEKLRRELEQELKMNCEEPRSH
AWYHGAIPRQVAENLVQRDGDFLVRDSLSSPGSYVLTCQWRNAPQHFKVNKKVVMLNEAY
SKVEYRLDKDGFDSVPSLIRFYVGNRKPVSQVVGAIIFQPINRSLPLRYMEEKYALSGNQ
REAGLVAQEKPCQKRLSLNITNGIGHPVQDGSHCPDNSLSRSSHLRLKDRCGSQPASLNQ
VQERRRPLKAHQSDSFLPLGSKPQSQQSPDPLLPSPKSPVFRTGSEPALSPCVPRRSAEH
QAAAGQAIRGSDSQLCPKPPPKPSKLLLAQSPQAPSVQPSRSPASSPSWAVSPLAASSCS
AATACPKTSQRTYMQLSDCRPSRSPGKAPNSYHHTIEASEHTSEEEEEEDGERDLPKRGK
VRGGFRRPVEETESMFRPTDFESRLLPPENKPLEMVVLRKAKELVLSHDHQSLARHLLMA
DCQVARILGVTPEMKGQMGVSSGLELVTLPHGRQLRLDLMERHHTMAIGVAVDILGCTGS
VEERASTLNRIILVAQELKDEVGDLYAFTALMKALDFQQISRLEETWTTLRRNFTQAAIS
YEKILKPFYKSLYEGTVSSAAPSSKALCLPMLLPLLTLMERPLIPPEGAEFWETSDEGCD
IMLRHLEAARIVAQNAQSHTSNAQMILKGFEFDEGLLEVFKTDFQLRLLWGSRGATVNQS
DRYNKFNLILTALSRKLEPPATTQPLI

>Homo sapiens_SH2D3C(ENSP_317817)
MTEGTKKTSKKFKFFKFKGFGSLSNLPRSFTLRRSSASISRQSHLEPDTFEATQDDMVTV
PKSPPAYARSSDMYSHMGTMPRPSIKKAQNSQAARQAQEAGPKPNLVPGGVPDPPGLEAA
KEVMVKATGPLEDTPAMEPNPSAVEVDPIRKPEVPTGDVEEERPPRDVHSERAAGEPEAG
SDYVKFSKEKYILDSSPEKLHKELEEELKLSSTDLRSHAWYHGRIPREVSETLVQRNGDF
LIRDSLTSLGDYVLTCRWRNQALHFKINKVVVKAGESYTHIQYLFEQESFDHVPALVRYH
VGSRKAVSEQSGAIIYCPVNRTFPLRYLEASYGLGQGSSKPASPVSPSGPKGSHMKRRSV
TMTDGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPAYS
TVTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHTLGKASP
SPSLSSYSDPDSGHYCQLQPPVRGSREWAATETSSQQARSYGERLKELSENGAPEGDWGK
TFTVPIVEVTSSFNPATFQSLLIPRDNRPLEVGLLRKVKELLAEVDARTLARHVTKVDCL
VARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGCTGSAEE
RAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISRLEQTWVTLRQRHTEGAILYEK
KLKPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSAPPEGPEPWGSTEHGVEVVLAHL
EAARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGASSSQARRYEKF
DKVLTALSHKLEPAVRSSEL

>Pan troglodytes_SH2D3C(ENSPTRP_36571)
MTEGTKKTSKKFKFFKFKGFGSLSNLPRSFTLRRSSASISRQSHLEPDTFEATQDDMVTV
PKSPPAYARSSDMYSHMGTMPRPSIKKAQNSQAARQAQEAGPKPNLVPGGVPDPPGLEAA
KEVMVKATGPLEDTPAMEPNPSAVEVDPIRKPEVPTGDVEEERPPRDVHSERAAGEPEAG
GDYVKFSKEKYILDSSPEKLHKELEEELKLSSTDLRSHAWYHGRIPREVSETLVQRNGDF
LIRDSLTSLGDYVLTCRWRNQALHFKINKVVVKAGESYTHIQYLFEQESFDHVPALVRYH
VGSRKAVSEQSGAIIYCPVNRTFPLRYLEASYGLGQGSSKPASPVSPSGPKGSHMKRRSV
TMTDGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPAYS
TVTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHTLGKASP
SPSLSSYSDPDSGHYCQLQPPVRGSREWAATETSSQQARSYGEKLKELSENGAPEGDWGK
TFTVPIVEVTSSFNPATFQSLLIPRDNRPLEVGLLRKVKELLAEVDARTLARHVTKVDCL
VARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGCTGSAEE
RAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISRLEQTWVTLRQRHTEGAILYEK
KLKPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSAPPEGPEPWGSTEHGVEVVLAHL
EAARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGASSSQARRYEKF
DKVLTALSHKLEPAVRSSEL

>Macaca mulatta_SH2D3C(ENSMMUP_21587)
MTEGTKKTSKKFKFFKFKGFGSLSNLPRSFTLRRSLAPISRQSHLEPDIFEATQDDMVTV
PKSPPAYARSSDMYSHMGTMPRPSIKKAQNSQAVRQAQEVGPKPNLVPRGVPDPPGLEAA
KEVMVKANGPLEDIPAVEPNPSAVEVDPIRKPEVPTGDTEEERPPRDVHSERQAGEVAGW
LFLKFSKEKYILDSSPEKLHKELEEELKLSSTDLRSHAWYHGRIPREVSETLVQRNGDFL
IRDSLTSLGDYVLTCRWRNQALHFKINKVVVKAGESYTHIQYLFEQESFDHVPALVRYHV
GSRKAVSEQSGAIIYCPVNRTFPLRYLEASYGLGQGSSKPASPVSPSGSKGSHMKRRSVT
MTDGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPAYST
VTRVHAAPAAPSATALPASPVTRRSSEPQLCPGSAPKTHGESDKGPHTSPSHTLCKTSPS
PSLSSYSDPDSGHYCQLQPPVRGSREWAAAEASSRQARSYGEKLKELSENGAPEEDWGKT
FTVPIVEVTSSFNPATFQSLLIPRDNRPLEVGLLRKVKELLAEVDARTLARHVTKVDCLV
ARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGCTGSAEER
AALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISRLEQTWVALRQRHTEGAILYEKK
LKPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSAPPEGPEPWGSTEHGVEVVLAHLE
AARTVAHHGGLYNTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGASSSQARRYEKFD
KVLTALSHKLEPAVRSSEL

>Callithrix jacchus_SH2D3C(ENSCJAP_36925)
MHSERAAGELEAGGDYVKFSKEKYILDSSPEKLHKELEEELKLSSTDLRSHAWYHGRIPR
EVSETLVQRNGDFLIRDSLTSLGDYVLTCRWRNQALHFKINKVVVKAGESYTHIQYLFEQ
ESFDHVPALVRYHVGSRKAVSEQSGAIIYCPVNRTFPLRYLEASYGLGQGSSKAASPASP
SGPKGSHMKRRSITMTDGLTADKVTRSDGCPTSMSLPRPRDSIRSCALSMDQIPDLHSPM
SPISESPSSPAYSTVTRVHAAPAAPSATALPASPVARRSSEPQLCSGSAPKIHGESDKGP
HASPSHTLCKASPSPSLSSYSDPDSGHYCQLQPPVRGSREWAAAEASSRQARSYGEKLKE
LSENGAPEGDWGKTFTVPIVEVTSSFNPATFQSLLIPRDNRPLEVGLLRKVKELLSEVDA
RTLARHVTKVDCLVARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIML
AVDILGCTGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISRLEQTWVTL
RQRHTEGAILYEKKLKPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSAPPEGPEPWG
STEHGVEVVLAHLEAARTVAHHGGLYHTNAEVKLQVLHCRPELLEVSARSQMRLLWGSQG
SSSSQARRYEKFDKVLTALSHKLEPAIRSSEL

>Mus musculus_SH2D3C(ENSMUSP_73866)
MTEMPKKTGRKFKFFKFKGLGSLSNLPRSFSLRRSSASASIRSCPEPDTFEATQDDMVTL
PKSPPAYARSSDMYSHMGTMPRPNIKKAQKQQAVQKAQEVSRESHLVSRRLPEPPDLEAA
KEAGEGTEALLEDTAPSAVEVDPMRELEDLTVDTEKEQVPGDVSPERTAAELEAAGDYVK
FSKEKYILDSSPEKLHKELEEELKLSSTDLRSHAWYHGRIPREVSETLVQRNGDFLIRDS
LTSLGDYVLTCRWHNQALHFKINKVVVKAGESYTHIRYLFEQESFDHVPALVRYHVGSRK
AVSEQSGAIIYCPVNRTFPLRYLEASYGLSQGSSKTASPASPSGSKGSHMKRRSITMTDG
LTTDKVTRSDGCPNSTSLPHPRDSIRNCALSMDQIPDLHSPLSPISESPSSPAYSTVTRV
HAPSATPSTSAQPASPVARRSSEPQLCPGNTPKPPGESDRAPHASPSHTLCKASPSPSLS
SYSDPDSGHYCQLQPPVRGSREQAAGETPRKARGSGERQKELLENGVSDGEWGKTFTVPV
VEATSSFNLATFQSQLIPKENRPLEVALLRKVKELLSEVDARTLARHVTKVDCLVARILG
VTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGCTGSAEERAALLH
KTIQLAAELRGTMGNMFSFAAVMGALEMAQISRLEQTWMTLRQRHTEGAILYEKKLKPFL
KSLNEGKEGPPLSNTTFPHVLPFITLLECDSAPAEGPEPWGSTEHGVEVVLAHLEAARTV
AHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGANSSQAWRYEKFDKVLTA
LSHKLEPAIRSSEL

>Rattus norvegicus_SH2D3C(ENSRNOP_21758)
MTEMPKKTGKKFXXXKFKGLGSLSNLPRSFSLRRSSASPSIRSCPEPDTFEATQDDLVTL
PKSPPAYARSSDMYSHMGTMPRPNIKKAQKQKAVQKAQEVSRESHLVSRGLPEPPDFEAA
KEAEKGTETPLEDTTPSAVEVDPMRKLAGLTVDTAEKQIPGDAYPERAAAELEAAGDYVK
FSKEKYILDSSPEKLHKELEEELKLSSTDLRSHAWYHGRIPREVSETLVQRNGDFLIRDS
LTSLGDYVLTCRWHNQTLHFKINKVVVEAGESYTHIRYLFEQESFDHVPALVRYHVGSRK
AVSEQSGAIIYCPVNRTFPLRYLEASYGLSQGSSKAASPASPSGPKGSHMKRRSVTMTDG
LTSDKVTRGDGCPNSTSLPHPRDSIRNCALSMDQIPDLHSPLSPISESPSSPAYSTVTRV
HAASAAPCTAQPASPVARRSSEPQLCPGGAPKPPGESDRGPHASPSHTLCKASPSPSLSS
YSDPDSGHYCQLQPPVRCSREPTAGETPRKARSSAERQKELSENGVPEGEWGKTFTAPVA
EATSSFNLATFQSQLIPKENRPLEVGLLRKVKELLSEVDARTLARHVTKVDCLVARILGV
TKEMQTLMGVRWGMELLTLPHGRQLRQDLLERFHTMSIMLAVDILGCTGSAEERAALLHK
TIQLAAELRGTMGNMFSFAAVMGALEMAQISRLEQTWMTLRQRHTEGAILYEKKLKPFLK
SLNEGKEGPPLSNTTFPHVLPFITLLECDSAPAEGPEPWGSTEHGVEVVLAHLEAARTVA
HHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGANSSQAWRYEKFDKVLTAL
SHKLEPAIRSSEL

>Canis familiaris_SH2D3C(ENSCAFP_29815)
MTEGPKKASRKFKFFKFKGLGSLSNLPRSFTLKRSSTSSSIESHLEPDTFEATQDDMVTV
PKSPPAYARSSDMYSHMGTMPRLSIKKARDPQATHKTKEVGLEPHLVAQGLPNPPGLEAA
KEVVVETKPPLEDTPAVGPNPSAMSPTEKPKDPRADRKEERDPRNVPPERVAGEPEAGGD
YVKFSKEKYILDSSPEKLHKELEEELKLSSTDLRSHAWYHGRIPREVSETLVQRNGDFLI
RDSLTSLGDYVLTCRWRNQALHFKINKVVVKAGESYTHIQYLFEQESFDHVPALVRYHVG
SRKAVSEQSGAIIYCPVNRTFPLRYLEACYGLGQGSSKAASPASPSGPKGGHMKRRSVTM
TDGLTADKVTRSSDGCPASTSLPHPRESIRNCALSMDQIPDLHSPMSPISESPSSPAYST
VTRVHATSAAPSATALPASPVTRRSSEPQLCPGSTPKPPGESDKGPYASPSHTLCKASPS
PSLSSYSDPDSGHYCQLQPPVRGSREWAMAEASGRQARSYGERLKELSENGASEGDWGRA
FTAPVVEATSSFNPATFQSLLIPKDNRPLEVGLLRKVKELLAEVDARTLARHVTKVDCLV
ARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGCTGSAEER
AALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQIARLEQTWVTLRQRYTEGAILYEKK
LKPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSAPAEGPEPWGSTEHGVEVVLAHLE
AARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGASSNQARRYEKFD
KVLTALSHKLEPAVRSSEL

>Felis catus_SH2D3C(ENSFCAP_1380)
MTEGPKKASRKFKFFKFKGLGSLSNLPRSFTLKRSSASISIRSHLERDTFEATQDDMMTV
PQSPPAYARSSDMYSHMGTMPRHSTKKARDQQATRETKEVGSESHLLPQDLPNPPGLEAS
KEVVVGTNAPLEDTPAVGPNPSVMGPVGEPEDPSADRKEETAPRNVPPERAAGEPEAGGD
YVKFSKEKYILDSSPEKLHKELEEELKLSSTDLRSHAWYHGRIPREVSETLVQRNGDFLI
RDSLTSLGDYVLTCRWRNQALHFKINKVVVKAGESYTHIQYLFEQESFDHVPALVRYHVG
SRKAVSEQSGAIIYCPVNRTFPLRYLEACYGLGQGSGKAAGPASPSGPKGSHMKRRSVTM
TDGLTADKVTRSDGCPTSTSLPHPRESIRNCALSMDQIPDLHSPMSPISESPSSPAYSTV
TRVHAAPAAPSATALPASPVTRRSSEPQLCPGSAPKPPGESDKGPYASPSHTLCKASPSP
SLSSYSDPDSGHYCQLQPPVRGSREWAAAEASSRQARSYGERLKELSENGAPEGDWGRAF
TVPIVEATSSFNPATFQSLLIPKDNRPLEVGLLRKVKELLAEVDARTLARHVTKVDCLVA
RILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGCTGSAEERA
ALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQIARLEQTWVTLRQRHTEGAILYEKKL
KPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSAPAEGPEPWGSTEHGVEVILAHLEA
ARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGASSNQARRYEKFDK
VLTALSHKLEPAVRSSEL

>Bos taurus_SH2D3C(ENSBTAP_20433)
MTEGTKKASKKFKFFKFKGFGSLSNLPRSFTLRRSLAPNSIRPQVEADTFDATQDDMVTV
PKSPPAYARSSDMYSHMGTMPRPSIKKAQGKQATQKAQEVGPEPQVVPRSLPDPPGLEAA
EKVVPGTIASREDTPTVGPNPSAVEVDPTRKPEDARPDTEEGRDPKNVPSERATAEPEAG
GDYVKFSKEKYILDSSPEKLHKELEEELKLSSTDLRSHAWYHGRIPREVSETLVQRNGDF
LIRDSLTSLGDYVLTCRWRNQALHFKINKVVVKAGESYTHIQYLFEQESFDHVPALVRYH
VGSRKAVSEQSGAIIYCPVNRTFPLRYLEACYGLGQGGGKAASPASPSGPKGSHMKRRSV
TMTDGLTADKVTRSDGCPTSTSLPHPRESIRNCALSMDQIQDLHSPMSPISESPSSPAYS
TVTRVHAAPAAPSATALPASPVTRRSSEPQLCPGSVPKPHGESDKGPYSSPSHTLCKASP
SPSLSSYSDPDSGHYCQLQPPVRGSREWAAAEASGRQARSYGEKLKELSENGASEGDWGR
TFTVPVVEATSSFNPATFQSLLIPKDNRPLEVGLLRKVKELLAEVDARTLARHVTKVDCL
VARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAMDILGCTGSAEE
RAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQIARLEQTWVTLRQRHTEGAILYEK
TLKPFLKSLNEGKEGPPLSNTTFPHILPLITLLECDSAPAEGPEPWGSTEHGVEVVLAHL
EAARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGASSSQARRYEKF
DKVLTALSHKLEPAIRSSEL

>Gallus gallus_SH2D3C(ENSGALP_8061)
MAEGQKRGGFKKFKFFKFKGFESLSSIPRSFTLRRVSVVPSSPESLGMCLPPPQGFLEEA
FDSTQDDLNTMPKGPGPYARSSDMYSHMGTMPRLSFGKVGKSLGKARGTQSCREKGSSRD
KIPSTAPRSPGAEKARMDQEIPGNSPSPGMEAPSPSLAPSPSAASGAETTDGDFQEKGQE
RPSESSPDSHHDGLESSSEYVKFSKEKYILDSSPEKLHKELEEELKLSSTDLRSHAWYHG
RIPREVSESLVQRNGDFLIRDSLTSVGDYVLTCRWRNEPLHFKINKVTVKSSDGRTRVQY
LFEQESFDNVPALVRFYVGNRKAISEQSGAIVYCPINRTFPLRYLEASYGLANGKHGGSH
SPASQKGGHIKRRSITMTDGLTADKITRAEGCSTSVSLPHHRDIIRNCAVSVDQIQDLHS
PMSPISENPTSPAYSTVTRLKPHACQAAGIAPASPVIRRSSEPQLCPGSSNKPLPDPAHS
THSTPCHGYARASPSPSVNSYSDPDTGHYCQLHPTSPSSRERPAHDTKQLPAKSYVERLK
VEEGQRGTVENGSGEAEGGQRLKGERDFVGFVPPTVETCSSFNPAAFQSLLIPLENKPLE
MAVLKKVKELVADADAKTLAKHITKVDCVVARILGVSAEMQRLMGVSSGMELLTLPHGHQ
LRLDLLERFHTMSIMIAVDILGCTGSTEERAALLHKTIQLAAELKSTMGNMFSFAAVMNA
LEMAQIARLEQTWMVLRQRHTEGAILYEKKLKPFLKSLNEGKEGPPLTNTTFPHVMPLVT
LLERDDALVDSPEPWEATDNGVEVVMAHLEAARMVAHHGGLYHTNAEVKLQGFQGRAELL
EIFSTEFQLRLLWGSRGAESSQAERYEKFDKVLTALSHKLEPAVRFSEL

>Taeniopygia guttata_SH2D3C(ENSTGUP_3731)
VQFSKEKYILDSSPEKLHKELEEELKLSSTDLRSHAWYHGRIPREVSESLVQRNGDFLIR
DSLTSLGDYVLTCRWRNEPLHFKINKVTVKSSDGHTRVQYLFEQESFDNVPALVRFYVGN
RRAISEQSGAIIYCPINRTFPLRYLEASYGLANGKHGGPHSPSSQKGGHIKRRSITMTDG
LTADKITRAEGCPTSVSLPHHRDIIRNCAVSVDQIQDLHSPMSPISENPASPAYSTVTRL
KPHACQASGITPASPVIRRSSEPQLCHGNNSKPLPDPAHSSHSTPCHGYARASPSPSLNS
YSDPDTGHYCQLHPSSPICRDRPAHDTKQLPTKSYVERLKAGQRLKAELDFKGFVPPTME
TTSSFNPAAFQSLLIPLDNKPLEMTVLKKVKELLAEVDVKTLAKHITKVDCLVARILGVT
VEMQRLMGVSSGMELLTLPHGHQLRLDLLERFHTMSIMIAVDILGCTGSTEERAALLHKT
IQLAAELKSTMGNMFSFAAVMSALEMTQIARLEQTWMVLRQRHTEGAILYEKKLKPFLKS
LNEGKEGPPLTNTTFPHIIPLVTLLERDEALTESPEPWEATDNSVEVVMAHLEAARMVAH
HGGLYHTNAEVKLQGFQGKAELLEVFSTEFQLRLLWGSRGAESSQAERYEKFDKVLTALS
HKLEPAVRFSEL

>Anolis carolinensis_SH2D3C(ENSACAP_6747)
MKVVSVVHTSSPSSAARPVGTQAMAESQKRGGGFKKFFKGFGSLSSLPRVFAFRRITPQS
HGGGPFSPNGFLAPTIESTQDDLDTGPKSPLPYARSCDMYSHMGTMPRTGKKAGKKDQVK
AKRTEEGKSQELHLALPRNVVRGPAGSQTLEPSPMNSASKCFPESIQTIEKQKRDVRDPL
PPLERLTIENVQDDMHAVTRSPPSPYEMYSHVGTLPRAKSGAKEAKEKVMKPKPDSVLSG
GTAIQECILSTGSPGGSISVAEEKVERHQDGLGSGSEYVKFSKEKYILDSSPEKLHKELE
EELKLSSTDLRSHAWYHGRIPREVSESLVQRNGDFLIRDSLTSLGDYVLTCRWRNEPLHF
KINKVMVKSSEGRTHIQYLFEQESFDNVPALVRFYVGNRKPVSEQSGAIFYCPINRTFPL
RYLEASYGLANGKHSGSHGHSNNQKGGHIKRRSITMTDGLTADKIIRGEGCPTSVSLPHH
RDIIRNCAVSVDQIQDLHSSISPISETPATPAYSTVSRLKPNGGQAGNSVTPGSPVTRRS
SEPQLCQGNGSKADPSDSSRSTPSHGYSRASPSPSVSSYSDPDTGHYCQLHPPSPVQWER
PPGEGKVPSTKGYVERLKGDEAQRGLGLNGSEAGPRRRPENDVVGLAVPVVERTSSFNPA
AFHSLLIPLENKPLEMAVLKKVKELLAEVDAKTLAKHITQVDCLVARILGVSKETQRLMG
VSSGMELLTLPHGHQLRLDLLERFHTMTIMIAVDILGCTGSMEERASLLHKTIQLAAELK
STMGNMFSFAAVMNALEMTQISRLEQTWMVLRQRHTEGAILYEKKLKPFLKSLNEGNEGP
PLSNTTFPHIVPLITLLERDTALPENPEPWENMDNSVEVVMAHLEAARMVAHHGGLYHTN
AEVKLQGFQPQPELLEVFHTEFQLRLLWGSRGAESSQGERYERFHKVLTALSHKLEPSVR
SSEL

>Xenopus tropicalis_SH2D3C(ENSXETP_47644)
LNETVNQGSSKFVGFFKMFGSLSSLPLPFRRASSKDIVTRDASFEKTQDDLTAIPRSPNY
ARSCDMYTHMGTMPRHSTKRGPKSRKERGNNGSSCNVPVDMPSQLANDQVDDDANDIIIV
PSLKASSRSTMLKKHDPLPDGVNLPVETLNDPLPRRQEIPAQDATDMCSGLDAGSEYVKF
SKEKYILDTPPEKLHKELEEELKLNSSDLRSHAWYHGRIPREVSESLVQRNGDFLIRDSL
TSLGDYVLTCRWKNEPLHFKINKVMVKTSDSYTRIQYLFEQESFDNIPALVRFYVGSRRS
VSEQSSALIYCPINRTYPLRYLEASYGLSPGRQGGARSPQKGHMKRRSITMTDGLTADKI
NKSNGCPNSGSSSPHHRDMIRNCAVSVDQIQDLHSPMSPISETPGSPAYSTVVRVKPPLS
GATPGSPVLRRSSEPYVCPANNKAALNMADSHHSSPSHTHRNISPSPSINSYSDPDNGHY
CQLRPASPTHDALSVSLPPKSYVERLRVDECAMAGGMRGVDDVDRDPGCFIVPTMEAKSS
FNPSNFKSTLIPSDNKPLEMSILKKVKELFAEVDAKTIAKHITKTDCEVARILCVTKEMQ
RIMGVSSGMELLTLPHGHQLRLDLLERFHTMSIMIAVDILGCTGSTEERAALLHKTIQLA
AELKGTMGNMFSFAAVMNALEMSQISRLEQTWVALRQRHTEGAILYEKKLKPFLKSMNEG
KESLPLSNTTFPHIIPLITLLERDNPLLDGGDPWDSSDNGVEVVMAHLEAARMVAHHGGL
YHTNAEMRLQGFHPRSDLLEVSSTEFQMRMLWGSRGALGSQVERYNKFDKVLAALSHKLE
PSVRFSEL

>Danio rerio_SH2D3C(ENSDARP_38222)
MIKRKLSFKWFGSLTNLRRKSDAQKDDESVKEMSTDDMGMHPRSPSYATSSEMYTHMGTM
PRHSKKDKNSKKSKTKDKANLTRSQSLRPDHVVESPLLSMLSGKGLEVLENPIIEDKTAY
IQNRDLPPPPCVDGHSTRLEDENKKLEVNFKHVDASNACLGASIELCVSQESTVQPVLPK
KRLKEGDKLMKDTEELKEDNNLIQLPQKTGNQMEKKIAVEEDANIVWNYKLDGQEEKELN
SELDITENQGEYVEFSKEKYLLESPPEKLRKELEEELKLSSSDMRSHGWYHGHIPREASE
TLVLRSGDFLVRDSLSTVGDYVLTCRWQQEVIHCRISKVLVKSGQTKIQYMLENESFDSV
PTLVRHHAGTGRAVCPRTGAQLLCPVNRTLPLRYLEATFALAGGRPGSAYSPSAQRGAHI
KRRSVTMTDGLTTEKIIPHSPSTVHHKDAMRNCAMSMDQIQEYRCPLSPVGETPQSPAYS
AISRHRHGSGGRVLAVIPPSPVMRRSSDPHLSPSSSNNNIPCSETGPSTYSTPAHGYQSE
SLEQGGSYCELRPGQAPIPPCKSYVERLKVEEGQSLGSGAPDGVEGFMLPLVETSSSFKP
GKYQSTLLPPENKPLEMSVLKRVKELLAEVDPKTAAKHITKADCTVARILGVTKEMQRMM
GVSSGLEQLTLPHGHQLRLDLLERFYTMSIMMAVDLLGCTGSTEERAALLHKTIQLAAEL
KSNMGNMYGFAAVMRALELPQISRLEQTWMTLRQRHTEGAILYEKKLKPFLKAMNDGKET
CVLSSTCFPHVVPVLSLLERSVAAGEALESWESVESGVDVVMSHLEAARTIAHHGGLYRT
NAESKLQDFQERKEVLEIFCTEFQMRLLWGSRGSEGSQTERYEKFDKVLTALSHKLEPPV
RHSEL

>Takifugu rubripes_SH2D3C(ENSTRUP_19212)
FKWFGSLTNLTSRHSEKPNIKATSGRSESLTAVGGQSVDDIEPCLQSPNYAHSDEMYTHV
GTIPRSQSQKKSCREMKQKKTSRPLPCTPAPGRPSPLTSPADHCRKPLDHTEVLWTETDV
SDTNSCVRKPSNMTKAASPQDLIEDPHEDNLKGSADTSGDYVKFSKDKFWLEPPSENLKK
QLDDELRLSGTNLKSHAWYHGPVPWEVAESLVVNHGEFLIRDSRSNHGDFVLTCHWQQKT
LHFLIRRTVLQSSETYTRVQYSLEEEAFDSLPALVHFYVGSKAALTQWSGAQIHRPINRT
LPLSYLDTAFGTIIGTPSSHGDSLCGQPRMCHRSYEGRMTTEGVDSEEYKDQCVCVCVPP
KIKSFLQQWAVCVLLIYESHSGHMKMTILPFSDTFRIHHSPPKQCRSATGVAARSPSEEV
EQKRQQCPQRCPQKTTSSTKTLPLRSPDHLLSSVAPSPSFSRHRSLPSPSSSLRRPQIRV
NLDCPSSNSDWNGYTELYPHAHSYVERLRVERFLECDQPRVEDGDAYCLPVVEAVSSFKP
SMYMSPLMAQENKPLEVGILRRVKELLSEVDHCTAAKHITKADCTVARILEVTPEVQKMM
GVSSGMELLTLPHGQRLRLDLLERFQTMATTLAVEMLGCTGTTEERASLLHKMIQIAAEL
KSTMGNMFGFAAVMRALELPQVSRLEQTWTALRQRHTEGAILYEKTLRPFMKSLNEGRES
CSLSNTTFPHVLPLLFLLEKSAAADEALEPWETVEAGVDVVMFHLGAARTFAQQGGVYRS
IAETKLKGFEERAEVTELFLTDFQMRLLWGSRGAEENQALRYGKFDQVLTALSNKLEPPV
RAG

>Tetraodon nigroviridis_SH2D3Ca(ENSTNIP_16186)
LPLQFSKDKYLLESPPEKLRKELEEELKLSAADIRSHGWYHGHIPREVSETLVLRNGDFL
VRDSLTSVGDFVLTCRWDNEALHFRISKVLVKSSETKVQYVLEADTFDSVQELVRFYVGQ
RKAVSQSNGVHIYCPVSRTLPLRYLEATFALACSKQGSAYSPSSPRGAHIKRRSVTMTDG
LTEKMISHSPSTIHHHKEAMRNCAVSMDQIQEYRCPLSPGGEAPHSPAYSAITRQRTHSG
GRALAVVPPSPVMRRSSDPQLSPSGPDGPPELPARPGQQSHPSESGSYCDLRACPAGPPK
PPAKSYVERLRGEEGRRDGGRPDGEAWPSAPHVETASSFRPSRFESPLLPAENKPLEMSV
LKRVKELLAEVDARTAATITMADCRVARILGVTPEVQRRMGVTSGLELLTLPHGHQLRLD
LLERFTTMSITVAVDLLGCTGSTEERAALLHKTIQLAAELKSGLGNMFGFAAVMRALELP
QISRLEQTWVTLRQRHTEGAILYEKKLKPFLKNINDGKESGAASTASFPHIIPILSLLER
GVAVGETPEPWESSEAGVDVVMYHLEAARTIAHHGGVYRSNAEAQLQGLQQRAEIYEIFQ
TEFQMRLLWGSRGSEGSQSERYEKFDKVLTALSHKLEPPVRHSEL

>Tetraodon nigroviridis_SH2D3Cb(ENSTNIP_19839)
VYNYGKREKRSFKGLKWFGSLTNLTNKSTTKAALGGGEGLTGAAPGGQPEDQVQPCLRSP
GYAHSSEMYTHVGTAPRRSSPLTPEAQHVSQADGCVRKPSNMAASGAKAASPQDLYVPMD
PIYEGAHTHKSAPTKSPRGVALKQEPDVLEPTAPEEKSPPFMFFSLTGSADSSGEYVKFS
KGKFWLEPLSENLKKQLEEELRLSSTNLKSHAWYHGPIPWEVSESLVVNHGDFLIRDSQS
NRGNFVLTSNWQQKTLHFLIRKAALQPGETYPRVQYSLEEEAFESLPALVHFYVGSRAPL
TQWSGAQIQRPVNRTMPLSYLETAFGAIIGSPSRHGDALCGQQNTSQTRPLLDCASWDLM
TKKSSYSRDKRLQREAPSLRMASILLDKLPKTFLVKPRSELSSDPPKRTTCFQISQLPKK
SVETLTGNDEVVRFTCQRKLVPSTLSPRQREDTDKKPLLHFLPKHTKRKTTPSPIIETLS
DPDSAKTKELKVPQSGNQTTSSTKTLALRAHGYVERLRVEDQPRTEDGDAYCLPVVEAAS
SFRPSVYVSALMKENKPLEVGILRRAKELLAEVDPRTAAKHITKADCTVARILDVTPEVQ
KMMGVGSGMELLTLPHGQRLRLDLLERFHTMATTLAVDVLGCTGTTEERAGLLHKMIQIA
AELKSTMGNMFGFAAVMRALELPQISRLEQAWTALRQRHTEGAILYEKTLRPFMKSLNEG
RESCSLSNTTFPHVLPLLFLLEKSAAASEGLEPWESVEAGVDVVMFHLGAARTFAQQGGT
YCSNAETKLKGFQERPEVTELFLTNFQMRLLWGSRGAEEKQALRYSKFDQVLTALSNKLE
PPVRPH

>Gasterosteus aculeatus_SH2D3Ca(ENSGACP_22976)
CSTQFSKEKYLLESPPEKLRKELEEELKLSAADIRSHGWYHGHIPREVSETLVVRNGDFL
VRDSLAGVGDYVLTCRWDNEVLHFKISKVLVRTVDAFTQVQYVLEADSFDSVQELVRFYI
GQRKPVSQSSGVHIYCPVSRTLPLRYLEATFALAASKQSSAYSPSSQRGAYIKRRSVTMN
DGLTMDKMISHRCCVFSPSTIHHHKDAMRNCAMSMDQIQEYRRPLSPVGETPRSPAYSAT
VTRQRAHSSGRVLAVVPPSPQMRRSSDPELSPPAGNNPAEHPAHTSHPPHSAPARHPGHQ
THSSETAGSYCDLRPCPAGPPKPPNKSYVERLRVEDGRADGARVEGEGVFSAPQVETASS
FRPSRYASCLMPADNKPLEMSVLKRVKELLAEVDARTAAVHITMADCTVARILGVTTELQ
RMMGVSSGLELLTLPHGHQLRLDLLERFYTMSIMMAVDLLGCTGSTEERAALLHKTIQLA
AELKSNLGNMFGFAAVMRALELPQISRLEQTWVTLRQRHTEGAILYEKKLKPFMKNMNDG
KESNALANTSVPHIIPILSLLERGMAVGEALEPWESAEVGVDVVMYHLEAARTMAHHGGI
YRSNTETKLQGFQERAEIHEIFQTEFQMRLLWGSRGSEGSQSERYEKFDKVLTALSYKLE
PPVRHSEL

>Gasterosteus aculeatus_SH2D3Cb(ENSGACP_19373)
RQVSESLVVNHGDFLLRDSQSRRGDFVLTVRWEQKTLHFVVTATAAVRSSETDPGVRYGL
GAEAFDCLPDLVGFFAGSGAALSRWSAARILRPVNRTLPLGYLETAFGAAVSPPSCRRGL
KGGSSEEEVRPGSDTLRSDRTVRPSEPPTFEHPKKKQDNVRLRCIRLDRRLNGHGDMSPA
SSTTGTRTRLCTHRCVRSPRVPRACSLPRSRRPTGPSSGSAASPRGQSSGRASQVGYATQ
SRTTTRCSTESAFVASDSRSRGPSQEAPPPDDPGSCYTELQPGPRSYVGRLRAEGGNAYQ
SPVVETASSFAPSRYRSPLMPAENRPLEAGVLRRVKELLAEVDARTAARHITAADCRVAR
ILEVTPEAQRMMGVSSGMELLTLPHGQRLRLDLLERFQTMATTLAVDVLGCTGTTEERAG
LLHKIIQVAAELKGTTGDMFGFAAVMRALELPQVSRLEQTWTALRQRHTEGAILYEKTLR
PFMKSLNDGRESCPLAGTTFPHVLPLLSLLEKGVTVGEWAEPWETAEAGLDVVMFHLGAA
RTIAQLGGVYRSNAESKLQGFPEQPEVLELFLTDFQMRLLWGSRGAEESQALRHAKFDQV
LTALSNRLEPPVRPR

>Oryzias latipes_SH2D3C(ENSORLP_12800)
YANHHTVMLPCSAALCRNYHTKEFITICMFSKEKYLLESPPEKLRKELEEELKLSPADIR
SHGWYHGHIPQEVSETLVVRNGDFLVHDSLTNVGDFILTCRWDNEVLHFKISKVLVKSNE
TKVQYMLESDCFDSVQELVRFYVGQRKPLSQSCAAHIYCPVCRTLPLRYLEATFALASSK
HGSAYSPSSQRGAHIKRRSVTMTDGLTTEKMIPHRTQLENECKTCMEQHVRMVQMKAVHH
HKDAMRNCAMSMDQIQEFRCPLSPVGETPLSPAHSAIARQRTHLSGRALAVVPPSPVMRR
SSDPQLSPTASSSPPELPTHTSQSANSSPAHYSSHQSHSSETAGSYCDLRPCASGPPKPP
TKSYVERLRVEERRKQEGKEEEEGTFSSPQVETASSFRPSRYESRLLPAENKPLEMSVLK
KVKELLAEVDARTAAKHITVYDCKVARIVGVTSEMQRMMGVSSGLELLTLPHGHQLRLDL
LERFFTMSIMMAVDLLGCTGSTEERAALLHKTIQLAAELKNNLGNMFGFAAVMRALELPQ
ISRLEQTWVTLRQRHTEGAILYEKKLKPFMKNMNDGKESSALSNTTFPHILPVLSLLERG
MAVGEVLEPWESTEVGVDVVMFHLEAARTIAHHGEIYRTNAENKLQGFQERPELGEIFQT
EFQMRLLWGCRGSEGSQSERYEKFDKVLTALSQKLEPPARHSEL

>Drosophila melanogaster_(FBpp0078859)
MGNTQARQLENRQVPNRRSSILWNFRYSNTVRRREDLAVMVHNSRMSISEWLDLLELQQY
EGNLQEFSTVDDVVDITDKELKQFGVRGAHRQRMVNSLLGVRAKRRQSMNLEAMSSAPRA
VPRRKNSCPLVYLGENPQDMAGSGDSGPGVITTKSGKVLKQLTFDETSTIYEELRPRSKC
NSPHWAIEDSRMEGYGSSNATTPLATAQPSPSEQQEAIALKKALEWELSLDARELRSHAW
YHGALPRQRAEEIVQREGDFLVRDCASQPDNYVLSCRSKAAVLHFVLNKLVLQPETVYER
VQYQFEEDAFDTVPDLITFYVGSGKPISSASGALIQFPCNRTYPLSFYGHKIVGNQLHTQ
MLAGLRGLSPLNSPMGSNGAVGAGMNATFRFEPQQQQQQQLSPMAGSPASPHCSPPRARR
EVPPPPRLPCKKQQRSQSLTPAQAMLVSNINKLQEQQLQMQELENGNGNGIMRFQTIARC
NPTSEQHLESKFTTHSLPRPNTSAAHALRQQAVARISSLARNCSLDSPSDSRPPSPPPKP
RKEPMAAVLAYQASGSDSGNGSGDSALGDACEASVQRGVIIKNPRFMTTSVSNGTLKSFT
EFDVLAAEEELFTMAIEEVKTASKFDFENFVTLLLPSVENKPLDGDALNTFKMMLLETGP
KLLAEHITRIDIALFLEEPSNEEDYYLSCSGLELLTLPHGKVFREDIIERTQCIKLMVAV
TILTCQTDLDRAQLLSKWIQIAVETKTALGNLFGFCAIMLGLCMQQIQKLDQAWHILRQQ
YTDSAFTFEAKLRPTLSIMNEASNPQAPNTTVPHVLLYALLIDRPVMDIINHSNIDDRPA
LYHTCIAPWESKADDFGMTINFQHLDASRGFLKNLELYRKNAKIILEDASPRLDELLADA
FRTEFHVKFLWGSSGATAKAEDRHNKLEKVLTLMADKFCMMAEQ

>Nematostella vectensis_(XP_001635407)
MSKKSNKLSRTFPGRVKNETKSRQPLPSGFKRFADFLTLRRKKRKGDSAARQLEKSPWFHGKITAEYAEM
LMRGAGEFLVREDPAMPGMYFIAVRNKEQETLHLAITKVNHSKGTRIKYRVEDSDYMFDGIPELIQFYIS
ERRPVSIRPPAVLTIAISKESALLKEEDFRGRTSTAGSARIHRTTRGRLERKRSDPVLSTRVPSRVFNIE
ADDDSSASVPDKDRPHSRSNPPSIYYDDKQKTAEGGELFSSATTQSLEDVLDPPQIERRRHLSSSGSAPS
LYRKRDSGEGPESTYDSPRSIAIPTTTLKHVSPYGRQGRKRSQESGPVQALKSKEGVPLKDYATPSSLPV
NGSSNSQDELDYDVPRPSSMVTDKNNDDTNSKRDSGVTRESSTERDRAGSGVTECAKPRQTRQEIYQSVL
QKLRDKIVRPFLEQSCVTLARYMTKVDLDVVWTSHMGEGEGEPEGVAEGLELLILPQGRDIRSALIERYT
NLTYWVGALVVAAGDLGPRTQVVTKLIELADVLSDKHGNLVSFMAVLEGLALPQVTRLHHTWSCLHHQYS
SSAIMYHSTLKPLAGLLSSGAPSPFPGVCLPYVVPLAKLLEMTTEDALGGWGQDDVVQGIETLLAHLDAG
RTLIQQLDAYKDEYLKRSHETIPEDELKIMDYFRSRVNVGDVLGLGSDAHVRTQKLVTLLNWLSENAERA
SKPSADIWQATNAMAISIVCKPFDFFAIMKSGRLKGQIGRMNRGANLSAKIRLFSLHLKFPTDEKFTISR
VCPGMTVKDLKNRIELETGVPRHLLRLRYLDGYDLTDDRRLSYYNMVPAATVQVLLWPEWVSLVTAACKG
DYYGNQIGVFNFFRGVLASQIRTPAKLGQNTPREFNEKALVALYIASHRGHVNVVSRLVESGVYPCTKLP
SGRSPLHAAVNRKQITCVSILIGELYIDRVILSSAGRD

>Hydra magnipapillata_(XP_004209418)
MSVILGSLMYNLDSEIQNTVGRMPIESLNLSPWFHGKIDRATISRLLKHDGDFIVREKSDNSGTNVLSVL
WKGSIKHFILKANDKGLYTLEGESFSSINALITHHYERRSVIQSSTGIILMNSVNRIFMDGDDYIVPQDD
VQLKCKLGGGHFGDVYKVLELCDKGDLLALLKKEGPNFTQMKLFDMSMDIARGMAYLEQKQIIHRDLAAR
NCLVTNDYDVKISDFGMSREEDDEGTYTIQTTKEIPFKWCAPEVWLDTKYSTKTDVWSYGVTLYEIYSLG
QQPYPGWTNKQAREEINAGYRMPSPAKTPPEVYELMRKCWHFSDFERPSFSEIINIFENIRLHIFKMNFL
K

>Strongylocentrotus purpuratus_(XP_798921)
MSLQDMTPEDLRKLLEEEFKLPSEDVRSHAWFHGGISREKAEKLIRENGDFLVRDSISKPGNFVLTVRWK
GVSMHFVVNKVVLKAHSPYASVQYQFEKECFDAIPSLIKFYVGNCRPVSQASGAVIQHPVNRTLPLSYTD
NKYAATNKSHSGGYIYGQLQKKVVTPRRASNGGEGLRQRSGSNPTPFHLNGGVEKQVVNRADSHPLLGRI
SPLSLSSSPTPSPLSREQRGYTRTGSEPILSPSMEYAQVGPIESDYAETKPCLNTSASDDEGSISMTSID
GSSTTASPARVPSVSPTPQIQVTPDPSEQTPLEGDADTKDTTESKAESTTVSMTESTTELTTESTTESTS
QSTANSTALSQSTAESTSLSTAESNAPAPATTSTTVETKTPSPQTTSSLVQPIIREHIYSEIDLPVDPVD
PKDTIRYTMLHDDDSNPIIPPIIQEPPQESSPVQIEEQNLDVKPRKRVNSGTRFSVLDSDYSRVAQRSSP
NHLEKKPQTLQTNLPLRETESVFYPQDFVSSLLQPENKPLDKTSMDTIRQMLFDANPLALARHLTLVDTE
VCRIGHGCNNNSMPGLELLCLPHGGQFRLDIMERHNSLKMFCMATLLTCDDLEVRVQVLHQWIQLAETLR
GSLGNLFSFSTIMDALATKQVAYLRSTWDQLRSRFTNTAVNYDTKLRSLLKSINAGENVVPLTKTSLPHI
LPIIQLLERDWSTALDRDWSQTVPKEVLLTVPNGETWEETAPSYGLDIMLGHLQNAHMLAQQTNLYRINA
HAKLAKHPPEEDLLDAFKTELHLRLLWGSKATTDNATERYRLLEQVLSIMAQKIEFSGNSV

>Anopheles gambiae_(XP_310126)
PLPKMSLFRSQSVLSAFEGISWSYKFGTASRRKKHAALVITSLPHMELGEWLQRLDLAEYGDKFRSFNGV
EELLFLSESDIKKLGIRNNAHRARIVSSLVALREKLVQGRSSLIKCVYRPHKCRLPYCPFFAGQKGSIKG
IILPGRQVWGESLSVNFTQKPFHDGGEVHVQFRSVCHGGWGQSVVCTDNKMTNNIGVVFGGAKCSLQETT
PDGGNEAVALKKALEWELSLDSRDLRSHAWYHGPIPRQRAEEIVQKEGDFLVRDCVSQPGNYVLTCRTKG
PTLHFVINKLLLQPETVYERVQYQFEDDAYDTVPDLITFYVGSGKSISVASGARIQFPCNRTYPLSFYAG
KCPQNAAGMAGIRGPSPLNSPSPVPSSPGFRYNPYTQQTSSYRSPMSSPPRTKRETPPRLPSKKQRSQSL
TPLHGAAGGQQRYSSADGVIGGNGGASDGGSKSSKPSRLAETPEKCNSADGVIHNSESGAGARPSEEKCS
SADGVVKSQTLTRPCSTEPNGLASLKGSQSSLPRSASLRGTHGGRGGMTSYHPSGSDSGNGSGDSAQSSA
TGEELAPPVARGVGGVVLRNPRFIPTSLSSITLRSHAEIDPVAAEEALLAMQIPTYEQVSRYDLENFNTL
LLPFCDCKPLDSGTLNTVRMMLCESGPRVIANHLTRVDIGLILEKDESRKDDPLSCTGLELITLEQGKQY
RLDLIERTECMKLLVAVTILTCQSDLERAETLNKWIQIAVETKTALGNLFGFSAIMLGLSMPQIQKLEST
WHTLRQKFTDSAFNFEAKLRPTLNSMNDCSNPQAPNTTIPHILPYVLVKDRTINDVFANTPSPCPTLIAS
CVTPWETITQDFGFSVLFAHLDAARSFINNISLYKKNAQTIMQDTSRLDPLMEDAFKTEFQMKFLWGSKG
ALVPAEERHAKFEHVLTVMAEKFCGDPSAG