>Homo sapiens PKN3 MEEGAPRQPGPSQWPPEDEKEVIRRAIQKELKIKEGVENLRRVATDRRHLGHVQQLLRSS NRRLEQLHGELRELHARILLPGPGPGPAEPVASGPRPWAEQLRARHLEALRRQLHVELKV KQGAENMTHTCASGTPKERKLLAAAQQMLRDSQLKVALLRMKISSLEASGSPEPGPELLA EELQHRLHVEAAVAEGAKNVVKLLSSRRTQDRKALAEAQAQLQESSQKLDLLRLALEQLL EQLPPAHPLRSRVTRELRAAVPGYPQPSGTPVKPTALTGTLQVRLLGCEQLLTAVPGRSP AAALASSPSEGWLRTKAKHQRGRGELASEVLAVLKVDNRVVGQTGWGQVAEQSWDQTFVI PLERARELEIGVHWRDWRQLCGVAFLRLEDFLDNACHQLSLSLVPQGLLFAQVTFCDPVI ERRPRLQRQERIFSKRRGQDFLRASQMNLGMAAWGRLVMNLLPPCSSPSTISPPKGCPRT PTTLREASDPATPSNFLPKKTPLGEEMTPPPKPPRLYLPQEPTSEETPRTKRPHMEPRTR RGPSPPASPTRKPPRLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDE IESLYCEKRILEAVGCTGHPFLLSLLACFQTSSHACFVTEFVPGGDLMMQIHEDVFPEPQ ARFYVACVVLGLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFC GTPEFLAPEVLTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPG FLSVQGLEFIQKLLQKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQPPFVPTLC GPADLRYFEGEFTGLPPALTPPAPHSLLTARQQAAFRDFDFVSERFLEP >Pan troglodytes PKN3 MEEGAPRQPGPSQWPPEDEKEVIRRAIQKELKIKEGVENLRRVATDRRHLGHVQQLLRSS NRRLEQLHGELRELHARILLPGPGPGPAEPVASGPRPWAEQLRARHLEALRRQLHVELKV KQGAENMTHTCASGTPKERKLLAAAQQMLRDSQLKVALLRMKISSLEASGSPEPGPELLA EELQHRLHVEAAVAEGAKNVVKLLSSRRTQDRKALAEAQAQLQESSQKLDLLRLALEQLL EQLPPAHPLRSRVTRELRTAVPGYPQPSGTPVKPTALTGTLQVRLLGCEQLLTAVPGRSP AAALASSPSEGWLRTKAKHQRGRGELASEVLAVLKVDNRVVGQTGWGQVAEQSWDQTFVI PLERARELEIGVHWRDWRQLCGVAFLRLEDFLXHCHQLSLSLVPQGLLFAQVTFCDPVIE RRPRLQRQERIFSKRRGQDFLRASQMNLGMAAWGRLVMNLLPPCSSPSTISPPKGCPRTP TTLREASDPATPSNFLPKKTPLGEEMTPPPKPPRLYLPQEPTSEETPRTKRPHMEPRTRR GPSPPASPTRKPPRLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEI ESLYCEKRILEAVGRTGHPFLLSLLACFQTSSHACFVTEFVPGGDLMMQIHEDVFPEPQA RFYVACVVLGLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCG TPEFLAPEVLTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPGF LSVQGLELIQKLLQKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQPPFVPTLCG PADLRYFEGEFTGLPPALTPPAPHSLLTARQQAAFRDFDFVSERFLEP >Gorilla gorilla PKN3 MEEGAPRQPGPSQWPPEDEKEVIRRAIQKELKIKEGVENLQRVATDRRHLGHVQQLLRSS NRRLEQLHGELRELHARILLPGPGPGPAEPVASGPRPWAEQLRAQHLEALRRQLHVELKV KQGAENMTHTCASGTPKERKLLAAAQQMLRDSQLKVALLRMKISSLEASGSPEPGPELLA EELQHRLHVEAAVAEGAKNVVKLLSSRRTQDRKALAEAQAQLQESSQKLDLLRLALEQLL EQLPPAHPLRSRVTRELRTAVPGYPQPSGTPVKPTALTGTLQVRLLGCEQLLTAVPGRSP AAALASSPSEGWLRTKAKHQRGRGELASEVLAVLKVDNRVVGQTGWGQVAEQSWDQTFVI PLERARELEIGVHWRDWRQLCGVAFLRLEDFLDNACHQLSLSLVPQGLLFAQVTFCDPVI ERRPRLQRQERIFSKRRGQDFLRASQMNLGMAAWGRLVMNLLPPCSSPSTISPPKGCPRT PTTLREASDPATPSNFLPKKTPLGEEMTPPPKPPRLYLPQEPTSEETPRTKRPHMEPRTR RGPSPPASPTRKPPRLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDE IESLYCEKRILEAVGRTGHPFLLSLLACFQTSSHACFVTEFVPGGDLMMQIHEDVFPEPQ ARFYVACVVLGLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFC GTPEFLAPEVLTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPS FLSVQGLELIQKLLQKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQPPFVPTLC GPADLRYFEGEFTGLPPALTPPAPHSLLTARQQAAFRDFDFVSERFLEP >Macaca mulatta PKN3 MEEGAPRQPGPTQWPPEDEKEVIRRAIQKELKIKEGVENLRRVATDRRHLGHVQQLLQSS NRRLEQLHGELRELHARILLPGPGPDPAEPVASGPRPWAEQLRARHLEALRRQLHVELKV KQGAENMTHTCASGTPKERKLLAAAQQMLRDSQLKVALLRMKISSLEASGSPEPGPELLA EELQHRLHVEASVAEGAKNVVKLLSSRRTQDRKALAEAQAQLQESSQKLDLLRLALEQLL EQLPPAHPLRSRVARELRTAVPGYPQPSGTPVKPTALTGTLQVRLLGCEQLLAAVPGRSP AAALAGSPSDGWLRTRAKQQRGRGELASEVLAVLKVDNRVVGQTGWGQVAKQSWDQTFVI PLERARELEIGVHWRDWRQLCGVAFLRLEDFLDNACHQLSLSLVPQGLLFAQVTFCDPVI ERRPRLQRQERIFSKRRGQDFLRASQMNLSMAAWGRLVMNLLPPCSSPSTISPPKGCPRT PTTSREASDPATPSNFLPKKTPLGEEMTPPPKPPRLYLPQEPTFEETPRTKRPHMEPRTR RGPSPPASPTRKAPRLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDE IDRCVRALQGTQDGWPGLMMLVPVSLISDWPGHPGSPSHGHPGASLPCLPDLGPEFSHNH PCSFYVACVVLGLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTF CGTPEFLAPEVLTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYP GFLSVQGLELIQKLLQKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQPPFVPTL CGPADLRYFEGEFTGLPPALTPPAPHSLLTARQQAAFRDFDFVSERFLEP >Callithrix jacchus PKN3 MEEGAPRQPGPSQWPPEDEKEVIRRAIQKELKIKEGVENLRRVATDRRHLGHVQQLLRSS NRRLEQLHGELRELHARILLPDPGPGLAEPVASGTRPWAEQLRARHLEALRRQLQVELKV KQGAENMTHTCASGTPKEKKLLAAAQQMLRDSQLKVALLRMKISSLEASGSPEPGPELLA DELQHRLHVEAAVAEGAKNVVKLLGSRRTQDRKALAEAQTQLQESSQKLDLLRLALEQLL ERLPPSHPLRSRVARDLRTAVPGYPQPSGTPVKPTALTGTLQVRLLGCEQLLTTVPGRSP VAALAGSPSEGWLRTRAKQQRGRGELVSEVLAVLKVDNRVVGQTGWGQVAEQSWNQTFVI PLERARELEIGVHWRDWRQLCGVAFLRLEDFLDNACHQLSLSLVPQGLLFAQVTFCDPVI ERRPRLRRQKRIFSKRRGQDFLRASQMNLSMAAWGRLVMNLLPPCSSPSTISPPKGCPRT PATPREASDPPPPSNFLPRKTPLGEEMMPPPKPPRLYLPQEPTSEETPRTKRPHMEPRTR RGPSSPASPTRKPPRLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLGRDE IDSLYCEKRILEAVGRTGHPFLLSLLACFQTSSHACFVTEFVPGGDLMMQIHEDVFPEPQ ACFYLACVVLGLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFC GTPEFLAPEVLTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNTDAPYPG FLSVQGLELIQKLLQKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTVQPPFVPTLC GPADLRYFEDEFTGLPPALTPPAPHSPLTARQQAAFRDFDFVSEQFLEP >Mus musculus PKN3 MEHRKPGTGQRAPKDEKEMVRRAIQKELKIKEGMENMRRVATDRRHLGHVQQLLRASNRR LEQLHGELRELHAQVLLPASAEPVTSEPQPRAEQSRARLSEALHRQLQVELKVKQGAENM IHTCASGTPKERKLLAAAQQMLKDSQLKVALLRMKISSLESSGSPEPGPDLLAEELQHRL RVEAAVAAGAKNVVKLLGGQRMQDRKALAEAQAQLQESSQKLDLLRLALELLLERLPPTH SLRSRVTQELWMAMLGNPQPLGTLVKPIALTGTLQVRLLGCKDLLVAVPGRSPMAVLAGS PSESWLRTRSRQQRGGGELASEVLAVLKVDNRVVGQTGWGLVAEKSWDQSFIISLDRARE LEIGVHWRDWRQLCGVAFLKLEDFLDNACHQLSLSLVPQGRLFAQVTFCEPVIERRPRLQ RQRCIFSKRRGRDFMRASQMNLSMAAWGRLVMSLLPPCSSPNTASPPKGRPSTAVCGTPS AASPSNFLPMKTLSKEDTKPPPKPPRLYLQEPAPGTPCTKRPHMDPRPAVVPALAALSTR KPPRLQDFRCLAVLGRGHFGKVLLVQYKGTGKYYAIKALKKQEVLGRDEIDSLYCEKRIL ETVGRTGHPFLLSLLACLQTSSHACFVTEFLPGGDLMAQIHEDVFPEPQACFYLACVVLG LQFLHEKRIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEVL TQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFECIVSADVPCPHFLSVQGLELIQ KLLQKSPEKRLGAGERDAEEIKVQPFFRTTNWQALLARTVQPPFVPTLCGPADLRYFEGE FTSLPPTLTPPVSQSSLTARQQAAFRDFDFVSEQFLES >Rattus norvegicus PKN3 MAPKRQSAILPQPETQTRCCPEAGGQVGLSRPAEGSTFLVLRSDSGFRASVHFSLSSVDR EVCVSYAQLRVVVWCFPRGLLGSVCFLHSSCEVHNPISGMPRGSSVEQALGSMLAVVTST NPWIRRCMCWRSLCLGAVRFLSGVFSESVQKSCTAVYDDQSSRMGWKKKEQQEAIEHIDE VQNEIDRLNEQASEEILKVEQKYNKLRQPFFQKRSELIAKIPNFWVTTFVNHPQVSALLG EEDEEALHYLTRVEVTEFEDIKSGYRIDFYFDENPYFENKVLSKEFHLNESGDPSSKSTE IKWKSGKERKLLAAAQQMLKDSQLKVALLRMKISGLEASGSPEPGPDLLAEELQHRLRIE AAVAAGAKNVVKLLGGQRIQDRKALAEAQAQLQESSQKLDLLRLALELLLERLPPTHSLR SRVTRELRMAMLGNPQPLGTLVKPIALTGEVLAVLKVDNRVVGQTGWGLVAEKSWDQAFS ISLDRVTFCEPVIERRPRLQRQRRVFSKRRGQDFLRASQMNLSMTAWGRLVMSLLPPCSS PSTVSPPKGCPSAAACETSSSASPSMVMRLPAPCDWAQTFPSYSNFRPVKTLPGEDMKPP PKPPRLYLQEPAPGTPCTKRPHMDPRTGVAPPLAALSTRNPPQLQDFRCLAVLGRGHFGK VLLVQYKGTGKYYAIKALKKQEVLGRDEIDSLYCEKRILETVGRTGHPFLLSLLACIQTS SHACFVTEFLPGGDLMMQIHEDVFPEPQACFYLACVVLGLQFLHEKRIIYRDLKLDNLLL DAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEVLTQEAYTRAVDWWGLGVLLYEM LVGDTEDEVFECIVNADVPCPHFLSAQGLELIQKLLQKSPEKRLGAGERDAEEIKVQPFF RPPFVPTLCGPADLRYFEGEFTSLPPTLTPPVPRRSLSARQQAAFRDFDFVSKRFLES >Oryctolagus cuniculus PKN3 VCPKPPCGSRALSAPCAAPLEDPPGLTLLRPQQPGSGQRPLEEEKEAVRRAIQKELKIKE GVENLLRVATDRRHLGHVRQLLRASNRRLEQLHAELQELHARVLVTGPCAPPSLHTEPVA SGPWPRAEQPRARHLEALRRQLQVELKVKQGAENMTHTCARGTPKERKLLAAAQQMLRDS QLKVALLRMKITSLEASGAPDRSPPPGPELLADELQHRLRIEAAVAEGAKNVVKLLGGRR TQDRKALAEAQAQLQESSQKLDLLRLALERLLEGLPPTHPLRSQVARELQAAPLLGNPQP SATLGKPTALTGTLHVRLLGCEQLLTTVPGRSPAAALAGSPSESWLRARAKQPRGGGGLT SELGRSCEGRPWGEVLAVLKVDNRVVGQTGWGQVAKQSWDQTFCHRPGARKARELEIGVH WRDWRQLCGVVFLRLEDFLDNACHQLTLSLVPQGRLFAQVTFCDPVVERRPRLQRQKCIF SKRRGQDFLRASQMNLSMAAWGRLVMSLLPPCSSPSTISPPKGGPQAPTTPRGPSEPVSP SDFLPKKIPLGEEMRPPPKPPRLCLPQERTPEETPCTKRPHMEPRPGLAAPQPASPTRKT PRLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKHEVLSRDEMESLYCEKRILEA VGRSGHPFLLSLLACFQTSSHACFVTEFVPGGDLMMQIHEEVFPEPQA >Canis familiaris PKN3 MEEGAPRQPGANQRPPEDEKEAIRRAIQKELKIKEGVENLRRVATDRRHLGHVQQLLRSS NRRLEQLHGELRALHARILLPGPGPGQAEPVAPGPQPPAEQPRARHLEALQRQLQVELKV KQGAENMTHTYANGTPKERKLLAAAQQMLRDSQLKVALLRMKISSLEASGSPEPGPELLA EELRHRLHIEAAVAEGAKNVVKLLGGQRTQDRKALAEAQAQLQESSQKLDLLRLALEQLL EGLPPAHPLRGRVARELRTAVSGNPQPSGVLVKPTAMTGTLEVRLLGCEQLLKAVPGRSP AAALAGSPSQGWLRGRAKPQRGGGDLASEVMAVLKVDNRGVGQTGWAPVAKQSWDQMFIV PLERARELEIGVRWRDWRQLCGVAFLRLEDFLDNACHQLSISLVPQGLLFAQVTFCDPVI ERRPRLQRQKRIFSKRRGQDFLRASQMNLSMAAWGRLVMSLLPPCSSPSTISPPKACPQT PATPRGAAEPASPSNVPPKKSPLGEEMRPPPKPPRLYLPREPTSEEIPRTKRPHMEPRTQ LGSSPPASAARKPPRLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDE MESLYCEKRILEAVGRTGHPFLLSLLACFQTSSHACFVTEFAPGGDLMMQIHEDVFPEPH ARFYLACVILGLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFC GTPEFLAPEVLTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNADAPYPH FLSVQGLELIQKLLQKCPEQRLGAGEQDAEEIKTQPFFRTTDWQALLARTVRPPFLPTLC GPTDLRYFEGEFTGLPPALTPPDPRSPLTARQQAAFRDFDFVSEGFLGP >Felis catus PKN3 SSAVPQSGADQQPPEDEKEVIRRAIQKELKIKEGVENLRRVATDRRHLGHVQQLLRASNR RLEQLHGELRALHARILLPGPGLAGTAPATTGPQPPAEQPRARHLEALQRQLQVELKVKQ GAENMTHTYASGTPKERKLLAAAQQMLRDSQLKVALLRMKISSLEASGSPEPGPELLAEE LRHRLRIEAAVAEGAKNVVKLLGTRRTQDRKALAEAQAQLQESSQKLDLLRLALEQLLEG LPPAHPLRGRVARELRTAVSGKPQPSGVLVKPTAVTGTLEVRLLGCEQLLTAVPGRSPAA VLAGSPSQGWLRARAKQQRGGGELASEVLAVLKVDNRVVGQTGWGPVTKQSWDQTFIVPL ERARELEIGVHWRDWRQLCGVAFLRLEDFLDNACHQLSLSLVPQGLLFAQVTFCDPVIER RPRLQRQKRIFSKRRGQDFLRASQMNLNMAAWGRLVMNLLPPCSSPSTISPPRACPQTPA TPRGAANPASPSDFPPKKSPLEEEVRPPPKPPRLYLPREPTPEEIPRTKRPHMEPRTRLG PPLPASATRKPPRLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEME SLYCEKRILEAVGHTGHPFLLSLLACFQTSSHACFVTEFAPGGDLMMQIHEDVFPEPQAR FYLACVVLGLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGT PEFLAPEVLTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNADAPYPRFL SVQGLELIQKLLQKCPEQRLGAGERDAEEIKTQPFFRTTDWQALLARTVQPPFLPTLRGP TDLRYFEGEFTGLPPALTPPDPRSPLTARQQAAFRDFDFVSEGFLGP >Bos taurus PKN3 MEEGAQRQPGAGHQPLEDEKEVIRRAIQKELKIKEGVENLRRVATDRRHLGHVQQLLRSS NRRLEQLHGELRELHARILLPGPGLGPAEPAASGPRPLAEQARARHLEALQRQLQVELKV KQGAENMTHTYASGTPKERKLLAAAQQMLQDSQLKVALLRMKISSLEASGSPEPGPELMV EELRHRLRIEAAVAEGAKNVVKLLGSRRTQDRKVLAEAQAQLQESCQKLDLLRLALEQLL ERLPPAHPLRGRVARELRTAASGNPQPSGTLVKPTAMTGTLQVRLLGCEQLLIAVPGRSP AAALAGSPSQGWLRSRAKQQRGGGELASEVLAVLKVDNRVVGQTGWGPVAKQSWDQNFVI ALERARELEIGVHWRDWRQLCGVAFLRLEDFLDNACHQLSLSLVPQGQLFAQVTFCDPVI ERRPRLQRQKRIFSKRRGQDFLRASQMNLSMAAWGRLVMSLLPPCSSPSTISPPKTCSQT PATPQRATDPDSPSNFPPKKTPLREEIQPPPKPPRLYLAQEPTPEEMPRTKRPHMEPRIR LEPPLPAPATRKPPRLQDFRCLAVLGRGHFGKVLLVQFKGTGQYYAIKALKKQEVLSRDE IESLYCEKRILEAVGCTGHPFLLPLLACFQTSSHACFVTEFAPGGDLMMQIHEDVFPEPQ ARFYLACVVLGLQFLHEQKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFC GTPEFLAPEVLTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNAEAPYPR FLSVQGLELIQKLLQKCPEKRLGAGERDAEEIKTQPFFRTTDWQALLARAVQPPFVPTLC GPTDLRYFEGEFTGLPPALTPPDPRSPLTARQQAAFRDFDFVSERFLEP >Equus caballus PKN3 DSSAIPQPGAGQRPPEDEKEVIRRAIQKELKIKEGVENLRRVATDRRQLGHVQQLLRSSN RRLEQLHGELRELHARILLPGPGPSPGLSPGPSPAGPRPPAEQPRAGHLEALQRQLQVEL KVKQGAENMTHTYANGTPKERKLLAAAQQMLRDSQLKVALLRMKISSLEASGSPEPGPEL LAEELRHRLHIEAAVAEGAKNVVKLLGSRRTQDRKALAEAQAQLQESSQKLDLLRLALEQ LLEGLPPAHPLRARVARELRTAVSGNPQPSGALVKPTAMTGTLQVCLLGCEQLLSAVPGR SPAAALAGSPSQGWLRGRAKQQRGGGELASEVLAVLKVDNRVVGQTGWGPVAKQSWDQTF VVPLERARELEIGVHWRDWRQLCGVAFLRLEDFLDNACHQLSLSLVPQGLLFAQVTFCDP VIEKRPRLQRQKRIFSKRRGQDFLRASQMNLNMAAWGRLVMSLLPPCSSPSTISPPKVCP QTPATRRGAADPASPSNFLPKKTPLGEEMRPPPKPPRLYLPWEPTPEETPRTKRPHMEPM TRLGPPPAASATRKPPRLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSR DEIESLYCEKRILEAVGCTGHPFLLCLLACFQTSSHACFVTEFAPGGDLMMQIHEDVFPE PQARFYLACVVLGLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTST FCGTPEFLAPEVLTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNADTPC PRFLSVQGLELIQKLLQKCPEKRLGAGEQDAEEIKTQPFFRTTDWQALLARAVRPPLVPT LCGPTDLRYFEGEFTGLPPALTPPDPRSPLTARQQAAFRDFDFVSERFLEP >Loxodonta africana PKN3 LNGRGQQSELDKWPFRQMVGAAWCDFSAFLQPGAGQRPPEDEKELIRRAIQKELKIKEGV ENLRRVVTDRRHLGHVQQLLRSCNRRLEQLHGELRELHARILLPSLGPGPSEPVALGPQL RAEQPRARHLEALRRQLQVELKVKQGAENMTHTCASGTPKERKLLAAVQQMLRDSQLKVA LLRMKISSLEASESPEPGHGPEGPEGSCLAPSSLGPELLVEELRHRLRIEVAVAEGAKNV VKLLGSRRTQDRKALVEAQAQLQESSQKLDLLRLALEQLLEGLPPAHPLRGSVARELQTA VPGNPQPSGTLVKPTTLTGTLQVHLLGCEHLLTQLPWLGAPPRAGFGPGPSSIVVLESWL VSRGLWGAAGDLCSQPALSPASGLTGEVLAVLKVDNRVVGQTGWGPVAKQSWDQTFVIPL ERARELEIGVHWRDWRQLCGVAFLRLEDFLDNACHQLSLSLVPQGLLFAQVTFCDPIIER RPRLQRQKRIFSKRRGQDFLRASQMNLSMVAWGRLVMNLLPPCSSPSTISPPRGCPQTPT TTRGAANPASPSNFLPKKSPLEEETKPPPKPPRLYLSPEPTPEETPPASPAGEDTPGPGM EGLEGKPPRLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLGRDEIESLYC EKRILEAVGCTGHPFLLSLLACFQTPSHTCFVTEFAPGGDLMMQIHEDVFPEPQARFYLA CVVLGLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFL APEVLTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNEDAPYPRFLSVQA LELIQKLLQKCPEQRLGAGERDAEEIKIQAFFRATDWQAMLTRTVQPPFVPTLCGPADLR YFEGEFTGLPPALTPPDPRSPLTARQQAAFQDFDFVSERF >Dasypus novemcinctus PKN3 MVPKRQSSLLPHSKRAKLLPIPGQRRHRAALDLPKGEKEQQEAIEHIDEVQNEIDRLNEQ ASEEILKVEQKYNKLRQPFFQKRSELIAKIPNFWVTTFVNHPQVSALLGEEDEEALHYLT RVEVTEFEDIKSGYRIDFYFDENPYFENKVLSKEFHLNESGDPSSKSTEIKWKSGKDLTK RSSQTQNKASRKRQHEEPESFFTWFTDHSDAGADELGEVIKDDIWPNPLQYYLVPDMDDE EGEGEEDDDDDEEEEGLEDIDEEGDEDEGEEDEDDDEGEEGEPGVGQRPPEDEKELIRRA IQKELKIKEGVENLRRVATDRRHLGHVQQLLRSSNRRLEQLHGELRELHARIQLPGPGPG PAESAASGPCPRAEQPRARHLEALQRQLQVELKVKQGAENMTHTYASGTPKERKLLAAAQ QMLRDSQLKVALLRMKISSLEASGSPEPGPELQAEELRHRLRIEAAVAEGAKNVVKLLGS QRTQDRKALAEAQAQLQESSQKLDLLRLALEQLLEGLPPAHPLRGRVARELRAAVPGNPQ PSGVLVKPTAVTGTLQVQLVGCEQLLTTVPGRSPAAALAGGLSEGWLRARAKPRGGGELA SEVLAVLKVDNRTVGQTGWGPVAGHSWDQTFVIPLERARELEIGVRWRDWRQLCGVAFLR LEDFLDNACHQLSLSLVPQGLLFAQVTFCDPVIERRPRLQRQKRIFSKRRGRDFLRASQM NLSMAAWGRLVMSLLPPCSSPSTISPPRGCPQTPATPRGSTSPTSPSNVPPRKVPVGEEM KPPPKPPRLYLPQQPTPEEIPVRGRGCRGGAGLGEGRKPLGPERPLPSQRTKRPHVEPWA RLAPSPAASPTRNPPQLRDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRD EVESLYCEKRILEAVGRAGHPFLLSLLACFQTPSHACFVTEFAPGGDLMMQIHEDVFPEP QARFYLACVVLGLQFLHEKKIIYRDLKLDNLLLDAHGFLKIADFGLCKEGIGFGDRTSTF CGTPEFLAPEVLTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNGDASYP HFLSVQGLELLQKLLQKSPERRLGAGEQDAEEIKTQPFFRTTDWQALLARTVRPPFVPTF CGPADLRYFEREFTVLPPALTPPDPRSPLTARQQAAFWDFDFVSERFLEL >Myotis lucifugus PKN3 MEEAALRQPGPDQRPPEDEKEAIRRAIQKELKIKEGVENLRRAATDRRHLGHVQQLLRTS NRRLEQLHGELQELHTRILLPGPPAEPVAPGPRPPPEQPRARHLEALQRQLQVELKVKQG AENMTHTYARGTPKGRKLLAAAQQMLRDSQLKVALLRMKISSLEASGSPEPGPELLAEEL RHRLRIEAAVADGAKNVVKLLGSRRMQDRKALAEAQAQLQESSQKLDLLRLALEQLLEGL PPAHPLRGRVARELRTAVSGNPQPSGMLVKPIAMTGTLQVHLLGCEQLLTAVPGRSPVTA LARSPSQGWLRGRARQQRGTGELASEVLAVLKVDNRIVGQTGWGPVAQQSWDQTFVIPLE RARELEIGVHWRDWRQLCGVAFLRLEDFLDNACHQLTLSLVPQGLLFAQVTFCDPVIERR PRLQRQKRIFSKRRGQDFLRASQMNLSMAAWGRLVMNLLPPCSSPSTISPPKGCPRTPAT PRGATSPASPSSFPPKKTPLGEEMRPPPKPPRLYLPREPALEETPRTKRPHMEPRTRLGS SPPASATRKPPRLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIES LFCEKRILEAVGRTGHPFLLSLLACFQTSSHACFVTEFAPGGDLMMQIHEDVFPEPQARF YLACVVLGLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTP EFLAPEVLTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNAEAPYPRFLS VQGLELIQKLLQKCPEKRLGAGEQDAEEIKTQPFFGTTDWQALLARAVQPPFAPTLCGPT DLRYFEGEFTGLPPALTPPDPRGPLTARQQAAFRDFDFVSERFLEP >Monodelphis domestica PKN3 METGVTPKGSSTVQLGLGENPLDPSSQHRLEGEKEVIRKAIQKELKIKEGAENLRRVTTA RRNLGHVDQLLRSSNRRLEQLHWDLQELNARILLPDETHSPAASEPHLREEKPVAKHLEA LRKQLQIELKVKQGAENMTNTYANGSPKERRLLSAAQQMLRDSKVKIELLRMQIGKLGAS GETLEPGPEQRRELRAGDLRHRFRIETAVAEGAKNVVKLLGGRRLQDRKALAEAQTRLRE SLQKLDLLRLALERLMTELPPAHPLRILVARELREGMPRSPQPTGSLIKPIALTGTLEVR LTGCQELLEVVPGRSRVAALMGSPGESRPWGWGKQQRVEELTKEVLAVLKVDNHMVGQTG WGPVSAQAWDQTFLIPLERSRELEIGVQWRDWRELCGVAFLRLEDFLDNARHTLSLGLEP QGQLFVEVMFCDPVIERRPRLQRQKRIFSKHRGQDFLRASQMNISMAAWGRLVMSLLPPC SSSTLSPPGRPSSTSPHDSPGSLSPSSFPLTKPLVEETTPRKALVGEQLPPKPPRLHLPL DSAFVESPCTKRPHMDYRNSLRQGPCATPIRKPPKFQDFCCIAVLGRGHFGKVLLAQYKK TGTFYAIKALKKQEVLSRDELESLYCEKRILEMVGHSGHPFLLSLLVCFQTPSHFCFVTE FVPGGDLMMRIHADVFPEPQARFYLACVVLGLQFLHEKKIVYRDLKLDNLLLDANGFLKI ADFGLCKEGMGFGDRTSTFCGTPEFLAPEVLTDESYTRAVDWWGLGVLLYEMLVGECPFP GDTEEEVFDCIVNEEAPYPHFLSVEGLALIQKLLQKCPEKRLGAGRRDAEEIKVHPFFRS TDWEALLSCRIQPPYVPMLRGPADLRHFDQEFTALPPALTPPDRHCPLTARQQAAFLGFD FVSDQFLEA >Ornithorhynchus anatinus PKN3 LELGAGERLLDPGFQQRLEDEKELIRRAIQKELKIKEGAENLRKAATDRHHLGHVERLLR SSNRKLEQLHWSLRELNARILLPDRAENRDGGCPGPAEGPAVSPDPCRWEEKPVARRVEA LRKQLQVELKVKQGAENMIQMYANGTPKERKLVATAQQMLGDSKLKVELLRMQIGKLGAG EATEPAARAGRGELRVEELRHRLRIEAAVAEGAKNVVKLLGGRRLQDRKALAEAQARLRE SSQKLDLLRLSLERLAAELPAAHPTRSLVSRELREGTLGSLCSPSALGKPTALTGTLEVR LIGCQELLRAVPGRSRVATVLGSPGESRPWSRGAKPPRNEELANEVLAVLKVDNRVVGQT GWGPVSKQGWDQNFLIPLERILEFQIGKIEYRYISHVTFMRLEDFLDNERHGLNLRLEPQ GMFLAEVTFCDPVIQRRPRLQRQKRIFFSKQRGEDFLRASQMNINIVTWGRLVLGLLPPC GSPSSTLSPPSRTPAHAPAARVASAPASASNRVPFPLTLEEEDPPPKPPRLFLPLEPVAG DSPCTKRPHMEGSRWRAGPRGPSAPIRTIPQLQDFRFVAVLGRGHFGKVLLVQAKGTGRH YAIKALKKQEILSRDELESLHCEKRILEVVGLAGHPFLLPLLACFQTPSHACFITEFAPG GDLMMRIHADVFPEPHARRFYSACVVLGLQFLHEKRIVYRDLKLDNLLLDAQGFVKIADF GLCKEGMGFGDRTSTFCGTPEFLAPEVLTDESYTRAVDWWGLGVLLYEMLVGECPFPGDT EEEVFDSIVNEEAPYPHFLSVEGLGLICKLLQKCPKQRLGASERDAEEVKVQPFFRVTDW AALLARRVQPPYVPPLRGPADVRHFDREFTVLPPALTPPNPRCPLTPRQQAAFQGFDFVS DRFLEA >Taeniopygia guttata PKN3 PSFQQKLEGEKELLRRAIQKELKIKEGAENLRKATTDRKNLVHIEHVLKSSNRKLEQLHW ELQELNARILITDKEKSTTGRRKPAESAGHGQHSRVGSLKKQLHVEMKVKQGAENMIQMY STSKERKLLATAQQMLQDSKTKIEIIRMHIVKVSQSAGGMEDRVDPSVRMGTTISALELR IEELRHHLRIEAAVAEGAKNVLKILGGSRVQDRKFLAEAQGRLQESSQKIDLLRFSLERQ LSELSPDHPKRALIKQELVNTSSLGARHGSIQPTSVIKPTALTGTLEVRLMGCQDLLENV PGRSRMTRSSPICGSPSDLRSLSRTRVGLGIHGRGVAGKYRNEEPSNEVLAVLKVDNKVV GQTNWGPVNNQAWDQSFAIELDRSRELEIAIYWRDWRELCAVKFLRLDDFLDNERHGMCL SLEPQGMLFAEVMFCNPVIERKPKLQRQKRIFPKQKGKEFLRAPQMNMNVAAWGRLMMSF LPPCSSISTLSPPLHDPNHTDFPPVSPQSHGDSNSSTSFSSVCFPFCYTELLSLTQTHTP LLSAHDLSFPRKRTVQLEDFHCIAVLGRGHFGKVLLAQYKATGKLYAIKALKKKDIIRRD EIDSLNCEKRIFEVVNSSDHPFLVNMFACFQTPHHACFVMEYTPGGDLMMRIHEDVFPEH MAQFYTACVVLGLQFLHEKKIVYRDLKLDNLLLDAEGFVKIADFGLCKEGIGFGDRTNTF CGTPEFLAPEVLTDISYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYP RFLSTEALSIIRKLLRKCPERRLGAGEKDAEEIKIQPFFKGIDWNVLFARRLKPPFVPSL RDPTDISNFDEEFTSQKPILTPPEEVSVLTHKEQTAFKDFDFVS >Pelodiscus sinensis PKN3 MDPEFQQKLEDEKELIRRAIQKELKIKEGAENLRKVTTDKKNLVHIEHVLKSSNRKLEQL HWDLQELTAQFVVTEKDGSMNLDRCLWERNPNPVARRIEALRKQLHIEMKVKQGAENMIQ MYSNATSKDRKLLATAQQMLQDSKTKIELIRMQIVKVSQLAGGIEYAMDPAVKVGATISL QELRIEELRHHLCIEAAVAEGAKNVVKILGGRRVQDRKVLAEAQSRLQESSQKIDLLRLA LEQQLNELSPDHPKWALIKQELVNASSQGAQHVAIQPFTSLIKPTALTGSLEVRLLGCQD LLEKVPGRSRVIGSSPNHESPSDMKSLTRARAGMSIHSRSTATKHLRNEELCNEVLAVLK VDNKVVGQTNWGPVNNQAWNQSFVIELDRSRELEIAVYWRDWRELCAVKFLRLDDFLDNE RHGMCLSLEPQGTLFAEVTFCNPVIERRSKLQRQKRIFPKQKGMQFLRASQMNINIATWG RLMMSILPPCSSMSTLSPTLGSPINSDFTSPALLQTDSVFMLDSDYPVVKLTFSEEPPPK PPRLFLTADSKEISPSPEDSPCVKRLHVEEKTCSSAVREAPNWASQRKRAVQLQDFRCIA VLGRGHFGKVLLGQYKATGKLYAIKAIKKQDIVSQDEIDSLYCEKRIFEVINSSSHPFVV NMFACFQTPDHACFVMEYVPGGDLMMHIHSDVFPEHVVQFYTACVVLGLQFLHENKIIYR DLKLDNLLLDAEGFVKIADFGLCKEGMGFGDCTKTFCGTPEFLAPEVLTDTSYTRVVDWW GLGVLIFEMLIGESPFPGDNEEEVFDSIVNEEVRYPQFLSSEARSILHKLLQKCPERRLG AGERDAEEIKTQPFFRVIDWDALFARELKPPFVPSLKAPTDISNFDEEFTSQKPILTPPD EIPVLSSEEQAAFKDFDFVSRHLLEV >Xenopus tropicalis PKN3 MEFRNAGPPELLDPGFQQQLEDSRDQLKREIQRELKIKEGAENLRKVSTDKKHQGHVESQ LRASNRRLQELHRQLQELNGRIVIMEKDQKQDGAMSPDPCLWEQSFDPWQRRVEALKRQL HIESKVKQGAENIIQMFSNGTSKDRKLLTTAQQMLQDSRIKTELLRMQIVKLTQAPGTTC ESQEAPETLSPPELRIEELRHHLRVETAVSEGAKNVVKLLGGRRLQDRKALAEAQSRLHE SCHKIDLLRLSLERCLAELPSDHPKQQLIKEELKNCPTTARSKDPGPSHPLTSLIKSTAL TGTLEIHLLGCQDLLETVPGRSRTTSVQGSPGESKNFIRYRPGGSTHGWGGSGRHLRSDE HCGDVMCVLKVDNKQVAHTSWGPVHNQCWDQRFTIELERSRELEISVHWRDWRELCAVCF LHLEDFLDNERHGMCLQLEPQGKLFAEVMFCNPVIERRGKVQRQKRIFPKQKGKDFLRAT QMNINFATWGRLMMSILPPCGAMSTLSPPLTVHTSANPQPYFAGARCSDFPVKKLLFSEE PSPKPPPKPPRLYLNSEGATPPSPAESPGRAVGKSMKRIHGEDGGTQSNAEPTKVHRRTT LQVDDFTFISVLGRGHFGKVLLGQFKETGKNFAIKALKKRDIVSRDELESLQCEKRIFEA VNSSGHPFLVNLFGCFQTQGHACFVMEYMPGGDLMMHIHSNVFSEPTARFYSACVVLGLQ FLHEKKIIYRDLKLDNLLMDASGFVKIADFGLCKEGMGFGDRTSTFCGTPEFLAPEVLTD TSYTYAVDWWGLGVLIFEMLVGECPFPGDDEEEVFDSIVNEEVRYPRFLSNDAINIIRKL LRKSPERRLGAGVGDAEEIKPQLFFQEIDWDALYAQQVKPPVVPILSDPFDIRNFDEEFT GQKAILSPSDDPRPLSSADQLLFKDFDFVSELLLAP >Danio rerio PKN3 a MSGVTLQSSALQGLAEGDLMDPEFQQRVEDAIALLRQEIQRELKIKEAAERLRRAVTNRK SAADVDGQLRASSRKLEQLHWELQELNARAMATQKENVMDDATSPDPCHWEEVTSPLGSH VRTLKKQLTMELKVKQGAENIIQTYTNSSVKDRKMLSTAQQMLQDSRTKIELLRMQIVKV TQAREGERETTQQEGRPSETISPLELRVEELRHHLRIEAAVAEGAKNVVKQLGVRKVQDR RALAEAQARLQESSQKLDLLRLSLEQQLGELPQDHPKRAAIKEELTVGSSPGIGLQRERL RSSSSASSSLFKPASLTGRLEVRLMGCQDLLESVPGRCRVSNMSSAPGSPSDSKSLRMRT GLSTRSTNGKTTKTDELSSEISAVLKVDNKIVGRTHWRPLSKDAWNQSFSIELERSRELE IAVYWRDWRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFTEVRFINPVIERHPKLQRQ KRIFPKEKGKNFLRAAQMNMNFATWGRLMMSVLPPCNSTITALSPPLPGSEPLSPPSVST PPSTGDSAVVKLNFSEERPTKPPRLHLAQNPSADESLSGTPARVNSTEDRRVLQARPASQ PTTQRQEGMQMEDFNCISVLGRGHFGKVLLAEFKRTGKLYAIKALKKGDVVTRDEVDSLM CEKRIFETINASRHPFLVNLYGCFQTPDHVCFVMEYSPGGDLMTHIHNNIFSERQARFYS ACVLLGLEFLHQNRIVYRDLKLDNLLMDSDGFVRIADFGLCKEGMGYGDRTSTFCGTPEF LAPEVLTDSNYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFMSPE SVSVIQKLLQKNSEKRLGAGEQDANEVKKHRFFQGIDWEALLAKRVKPPFLPSIKTAADV SNFDEEFTRLKPVLTPPQTPFFLSAEQQEFFADFDFSALH>Ciona savignyi PKN1 PPPPPDPAIPPEEQQKDPRIGGLEKQLRIEMMVKQGAENMMKSYTSGHGKDRKLIATAEQ MLSESKTKIEVIRMQILQLKTHAASVASRSTDGNDGLPVRIAMLRHHVKIESAIVEGSKN VVRFMAEGKQDLTQTICYFNPAIALFDTEARLLPLLSPTTPNHHHPLFKPHVKSHPSLIY LTLIRIWCFNNSFIVVILVLPPHHPNTSPTHPGKLEVRLVGCQDLLDNVPGRSRNMSIQL PATSPENRAWIRGGSKSFHGKASNKYNVKPDDLSSDASLFNHVPSGVLLEVALFWRFYNN CPHIEIIYTLSHRNHKVALNMHMTSQVTFSNPKIERKPKLQRQKKIFRNKGKSFLRAKQM NINIATWSRLMKRAIPPCNDPNTFSPPSDVPAQEPHPAGKPPLGNPPVKTDSLNVSLSLS HTHPHDSPPSPITPQEMMSNIELEKPKPAPRRNKESFIQWNQPSSPPKPARRSNTPQAPD SGAKPRQIVMEDFKTIAVLGRGHFGKVLLTQHKQTGRMYAIKALKKGDIIARDEIDSLMV ERRIFECATKVKHPFLVNLYACFQTPQHVCFVTEYASGGDLMLHIHTDVFNEPRTVFYTS CVVLGLQYLHENKIVYRDLKLDNL >Ciona intestinalis PKN2 CDITMADPDNIDVEDPRIQNRLEEVKEDIRKEIRKELRVKEGIENMKKATTDKKQLSSME NMLRISNRQLEDLHQELRELDAAQITRSISDNLDDYKSSGGGLIVESSSQEDPRIAGLEK QLRIEMMVKQGAENMMKSYTSGHSKDRKLIATAEQMLGESRTKIEVIRMQILQLKTHNAT ATSKNNEAVDGNNPLPVRVALLRHHVTIESAIVEGSKNVVRLCRLRGSRPIRRHCKRAEA QEKLQESAHKLDLLKLSLELRSIELPPGSNEKKELEAELSLLSPTHYRQSSDHKEDTNHV KRFSTVPKPAELTGKLEVRIIGCQELLENVPGRSRNVSVQLPASSPENRAAWIRGASKSF HGKTSNKYNVKPDDLSNEVSAVLKLDNVVIGQTLWRNAGQQCWNQQFISELERARELEIS VYYKDWRAMCGVKFLRLADFLDNRRHAMALQLEPSGVLFAEVTFSNPRIERKPKLQRQKK IFRNKGKSFLRAKQMNINIATWGRLMKRAIPPNEPSTFIPPSGGTRSSPKMKQRPASQDF DHVVEPSAQTREPPQPGITKERRSSATMPSSGKSPCTDNGTNQPRHHPPSLLGGVEHLNR PMRRHHRRSIQMSDFRPIAVLGRGHFGKVLLTQHKKTSNMYAIKALKKGDIIARDEIDSL MVERRIFECATKVKHPFLVNLFACFQTPEHVCFVTEYASGGDLMLHIHTDVFNEPRTVFY TSCVVLGLQYLHDNKIVYRDLKLDNLLLDKDGYLKIADFGLCKEGMGFGDRTGTFCGTPE FLAPEVLTDTSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLST DAISIMRRLLRRNPERRLGAGEKDAEDVKRQPFFKRMNWDLLFQKKIVPQFVPTIRSATD VSNFDEEFTTEKPILTPPHENPRHLSREEQKQFSNFDYFADWP >Branchiostoma floridae PKN2 MAAEPTHFQSDPASHFVNHIGQRYGMQDVSDSDIQQKLEYLREHIKNDIKKEYKIKEGAEKVRKVTTDKK SLANVDSIVKKSNKKIQELHEQLQELNAHIVVSQSASESADLTDSEPFSPDEKGSKRDSGTNFNSRVSAL QKQLTIEMKVKQGAENMLNMYSTGSSKDRKLLAEAQQMLKDSKTKIEIIRMQILKAETQTSQENHVPEAS SGDTATPSGSPLESGSADELRIATLRHHMKIESAIVEGAKNVVRLLGAGKETDKRAVSEKSRSRWSGMSL GEEASNGHWSPRVYHMRLWGSGTRRRQKRTITCTEEAQTKLQESSQKLDILKFSLEKHLKNMPEASDKRK EIESELSLTSPVSYRTSGSYAQQTYSAYPKPAALTGRLDVRLMGCQDLLENVPGRSRSSSPTFPVSSPGE TKSGGFMSAKRSFHGRNSSKTYSVKPEDLSNEVMAVMKLDNKMVSQTAWKPCSNQAWDQRFNIDLDRSRE LEIAIYWKDWRSLCGMKYLRLEDFLDNQRHGLCVDIEPTGKLFIEVTFYNPVIERKPKLQRQRKIFPKHK GKNFLRPGQMNINVATWGRLMKRALPQACGTSPSTFSPISEVGSGGATPVKPSTPHERTAAHRLEFEQEP PEKPPRGESLQDNNSGSKKNSVAEHEVQDALSAFDFLGGDQSPDTSLESPGIRPGALTAPPPVPPHQQEY TGTSSTMTMDNFRPVAVLGRGHFGKVLLAEY