>Homo sapiens SHF
MQQEGGPVRSAPCRTGTLEGSRQGSPGHRKRASPKGSLSSAQPHSWMLTPSPLNSHCAHR
EPISSSPQPVANGPKQKKKSNWRSTTRLRIIRLRDRLEPRPLAILEDYADPFDVQETGEG
SAGASGAPEKVPENDGYMEPYEAQKMMAEIRGSKETATQPLPLYDTPYEPEEDGATAEGE
GAPWPRESRLPEDDERPPEEYDQPWEWKKERISKAFAVDIKVIKDLPWPPPVGQLDSSPS
LPDGDRDISGPASPLPEPSLEDSSAQFEGPEKSCLSPGREEKGRLPPRLSAGNPKSAKPL
SMEPSSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSLS
LKSSQGFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKLPIKGAEHMSLLYPVAI
RTL

>Pan troglodytes SHF
MQQEGGPVRSAPCRTGTLEGSRQGSPGHRKRASPKGSLSSAQPHSWMLTPSPLNSHCAHR
EPISSSPQPVANGSKQKKKSNWRSTTRLRVIRLRDRLEPRPLAILEDYADPFDVQETGEG
SAGASGAPEKVSENDGYMEPYEAQKMMAEIRGSKETATQPLPLYDTPYEPEEDGATPEGE
GAPWPRESRLPEDDERPPEEYDQPWEWKKERISKAFAVDIKVIKDLPWPPPVGQLDSSPS
LPDGDRDISGPASPLPEPSLEDSSAQFEGPEKSCLSPGREEKGRLPPRLSAGNPKSAKPL
SMEPSSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSLS
LKSSQGFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKLPIKGAEHMSLLYPVAI
RTL

>Gorilla gorilla SHF
MVAQSLSDAHHALAIMLSERLWLGLELLNFSRRKISSDPPPYNFLEAREAALGHRWRMQQ
EGGPVRSAPCRTGTLEGSRQGSPGHRKRASPKGSLSSAQPHSWMLTPSPLNSHCAHRESI
SSSPQPVANGSKQKKKSNWRSTTRLRVIRLRDRLEPRPLAILEDYADPFDVQETDEGSAG
ASGAPEKVPENDGYMEPYEAQKMMAEIRGSKETATQPLPLYDTPYEPEEDGATPEGEGGP
WPRESRLPEDDERPPEEYDQPWEWKKERISKAFAVDIKVIKDLPWPPPVGQLDSSPSLPD
GDRDISGPASPLPEPSLEDSSAQFEGPEKSCLSPGREEKGRLPPRLSAGNPKSAKPLSME
PSSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSLSLKS
SQGFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKLPIKGAEHMSLLYPVAIRTL

>Pongo abelii SHF
MQQEGGPVRSAPCRPGTLAGSRQGSPGHRKRASPKGSLSSAQPHSWMLTPSPLNSHCAHR
EHISSSPPPVANGPKQKKKSNWRSTTRLRVIRLSDRLEPRPLAILEDYADPFDVQETGEG
SAGASGAPEKVPENDGYMEPYEAQKMMAEIRGSKETATQPLPLYDTPYEPEEDGATPEGE
GAPWPRESRLPEDDERPPEEYDQPWEWKKERISKAFAVDIKVIKDLPWPPPVGQLDSSPS
LPDGDRDISGPASPLPEPSLEDSSAQFEGPEKSCLSPGREEKGRLPSRLSAGNPKSAKPL
SMEPSSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSLS
LKSSQGFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKLPIKGAEHMSLLYPVAI
RTL

>Macaca mulatta SHF
EAALGHRWRMQEGGPLRSAPCRPGTLHGSRQGSPGHTKWAFPKASLSSAQPHSWMLTRSP
LNFHCAHREPRSSSPPPVANGPKQRKKSNWRSTTRLRVIRLSDRLEPRPRTILEDYADPF
DVQETGEGSAGASGAPEKVPENDGYMEPYEAQKMMAEIRGSKETATQPLPLYDTPYEPEE
DGATPEGEGAPWSRESRLPEDDERPPEEYDQPWEWKKERISKAFAVDIKVIKDLPWPPPV
GQLDSSPSLPDGDRDISGPASPLPEPSLEDSSAQFEGSEKSCLSPGREEKGRLPPRLSAG
NPKSAKPLSVEPSSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSET
SKNDFSLSLKSSQGFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKLPIKGAEHM
SLLYPVAIRTL

>Callithrix jacchus SHF
MVARSLCDAHHARAIMLSERLWLRLELSPKFTRRKISSDPPPHNFRLEKLEAALGHRWKM
QQEGRPVRSSPCRPGTLECSRQGSGYRKWESLKGSLSSGQPHSWMITQFPLNSHCLHREP
ISSSLPPVANRPKQEKISNWRSTTRLRVLGLSYRLEPRRIELAILEDYADPFDVQETGED
SAGASGAPEKVPENDGYMEPYEAQKMMAEIRGSKETAAQPLPLYDTPYEPEEDGATPEGE
GAPWPRESRLPEDDERPPEEYDQPWEWKKERISKAFAVDIKVIKDLPWPPPVGQLDSSPS
LPDGDRDISDPASPLPEPSLEDSSAQFEGSEKSCLSPGREEKGRLPPRLSAENPKSAKPI
SVEPSSPLGEWDPALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSLSL
KSSQGFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKLPIKGAEHMSLLYPVAIR
TL

>Mus musculus SHF
MEPYEAQKMMAEIRGSKETAAQPLPLYDTPYEPEDEGASPEGEGTPWPRESRLPEDDERP
PEEYDQPWEWKKERISKAFAAQFEGSENCLSPGREEKGRLPPRLSAGNPKSAKPLGMEPS
SPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSLSLKSSQ
GFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKLPIKGAEHMSLLYPVAIRTL

>Rattus norvegicus SHF
MEPYEAQKMMAEIRGSKETAVQPLPLYDTPYEPEDEGASLEGEGAPWPRESRLPEDDERP
PEEYDQPWEWKKERISKAFAVDIKVIKDLPWPPPVGQLDSSPSLPDGDRDISGPASPLPE
PSLEDSSAQFEGSEKNCLSPGREEKGRLPPRLSAGNPKTAKPLGAEPSSPLGEWTDPALP
LENQLVPRGHQPNRCREPAQAVQRGQLPGAQQ

>Oryctolagus cuniculus SHF
AILEDYADPFDVQESGEGSAGTSGAPEKVPENDGYMEPYEAQKMMAEIRGSKETAAQPLP
LYDTPYEPEEEAAPPEGEGAPWPRESRLPEDDERPPEEYDQPWEWKKERISKAFAVDIKV
IKDLPWPPPVGQLDSSPSLPDGDRDVSGPASPLPEPSLEDSSAQFEGPEKSCLSPGREEK
GRLPPRLSMGNPKPAKALNTEPGSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKE
ASYLVRNSETSKNDFSLSLKSSQGFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASR
KLPIKGAEHMSLLYPVAIRTL

>Canis familiaris SHF
LFFLGYFPVRRPWGKGGVQALGTQTCEVPRVSCELGRGTDGDRCAPTGARVGTRGGLTFG
PGFASPALGVAHFLPVCPHPLEARTPPPPRQGEADPDRERNPAPPLLPTSPAPPPPGGAP
PPHPPPAGRRAPRAPLAQSGWPHVTERSSPGGLRPGAAGAGEPGERPGGVAPGPGGAGAG
PGGGGSGGVSKWLREHLGFRGGGGGGGGGKPAPPEPDYRPPAPSPAAPPAPPPDILAAYR
LQRERDFEDPYSGGPSSSAAAPATPTAPGPTPPPRHGSPPHRLIRVETPGPPAPPPEERI
SGPPAGSDRLAILEDYADPFDVQETGEGPAGASGAPEKVPENDGYMEPYEAQKMMAEIRS
SKETAAQPLPLYDTPYEPEEEGTTPEGEGTPWPRESRLPEDDERPPEEYDQPWEWKKERI
SKAFAVDIKVIKDLPWPPPVGQLDSSPSLPDGDRDISGPASPLPEPSLEDSSAQFEGSEK
SCLSPGREEKGRLPPRLSAGNPKSAKPLGMEPSSPLGEWTDPALPLENQVWYHGAISRTD
AENLLRLCKEASYLVRNSETSKNDFSLSLKSSQGFMHMKLSRTKEHKYVLGQNSPPFSSV
PEIVHHYASRKLPIKGAEHMSLLYPVAIRTL

>Felis catus SHF
LAILEDYADPFDVQETAEGPAGASGAPEKVPENDGYMEPYEAQKMMAEIRSSKETAAQPL
PLYDTPYEPEEEGTTPEGEGTPWPRESRLPEDDERPPEEYDQPWEWKKERISKAFAVDIK
VIKDLPWPPPVGQLDSSPSLPDGDRDISGPASPLPEPSLEDGSAQFEGSEKSCLSPGREE
KGRLPPRLSAGNPKSAKPLNVEPSSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCK
EASYLVRNSETSKNDFSLSLKSSQGFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYAS
RKLPIKGAEHMSLLYPVAIRTL

>Bos taurus SHF
MLLSGAPPAGXPAPPPDILAAYRLQRERDFEDPYSGGPSGTATLATPSAPGPTPPPRHGS
PPHRLIRVETPGPPAPPPEERISGHPASSDRLAILEDYADPFDVQETGEGPIGAAGAPEK
VPENDGYMEPYEAQKMMAEIRGSKETAAQPLPLYDTPYEPEEEGATPEGEGAPWPRESRL
PEDDERPPEEYDQPWEWKKERISKAFAAQFEGSEKSCLSPGREEKGRLPPRLSAGNPKSA
KPLSMEPSSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDF
SLSLKSSQGFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKLPIKGAEHMSLLYP
VAIRTL

>Equus caballus SHF
PMLLSGASPAGSGPGPRAQGSAGGGPGGSRRGTGGAGAGPGGGSSGGVAKWLREHLGFRG
GGGGGGGGKPAPPEPDYRHPAPSPAAPPAPPPDILAAYRLQRERDFEDPYSGGSSGSVAL
ATPAVPGPTPPPRHGSPPHRLIRVETPGPPAPPPEERISGPPASSDRLAILEDYADPFDV
QETGEGPAGASGAPEKVPENDGYMEPYEAQKMMAEIRGSKEPAAQPLPLYDTPYEPEEEG
ATPEGEGAPWPRESRLPEDDERPPEEYDQPWEWKKERISKAFAAQFEGSEKSCLSPGREE
KGRLPPRLSTGNPKSAKPLSMEPSSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCK
EASYLVRNSETSKNDFSLSLKSSQGFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYAS
RKLPIKGAEHMSLLYPVAIRTL

>Loxodonta africana SHF
AILEDYADPFDVQETGEVPAGASGAPEKIPENDGYMEPYEAQKMMAEIRGCKETAAQPLP
LYDTPYEPEEEGAAPEGEGAPWSWESRLPEDDERPPEEYDQPWEWKKERISKAFAVDIKV
IKDLPWPPPVGQLDSSPSLPDGDRDISGPASPLPEPSLEDSSAQFEGSEKSCLSPGREEK
GRLPPRLSAGNPKTAKPLSMEPSSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKE
ASYLVRNSETSKNDFSLSLKSSQGFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYTSR
KLPIKGAEHMSLLYPVAIRTL

>Dasypus novemcinctus SHF
YRPPAPNPAAPPAPPPDILAAYRLQRERDFEDPYSGGPSGSAALATPTAPGPTPPPRHGS
PPHRLIRVETPGPPAPPPEERISGPPASSDRLAILEDYADPFDVQESGEGTAGASGAPEK
IPENDGYMEPYEAQKMMAEIRGSKETGAQPLPLYDTPYEPEEEEATPESEGAPWPRESRL
PEDDERPPEEYDQPWEWKKERISKAFAAQFEGSEKSCLSPGREEKGRLPPRLSAGNPKPA
KPPSVEPSSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSGTSKNDF
SLSLKSSQGFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKLPIKGAEHMSLLYP
VAIRTL

>Myotis lucifugus SHF
LAILEDYADPFDVQETGDSLVGASGAPEKVPENDGYMEPYEAQKMMAEIRGSKETATQPL
PLYDTPYEPEEEGATPEGEGAPWPRESRLPEDDERPPEEYDQPWEWKKERISKAFAVDIK
VIKDLPWPPPVGQLDSSPSLPDGDRDVSGPASPLPEPSLEDGSAQFEGSEKSCLSPGLEE
KGRLPPRLSAGNPKSAKPLSMEPSSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCK
EASYLVRNSETSKNDFSLSLKSSQGFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYAS
RKLPIKGAEHMSLLYPVAIRTL

>Pteropus vampyrus SHF
NQQREEPPKSASCGPSLEGSPGYRRWAPSKGSLSSGQSSLWVSKWSPLNFHLIHMEPTPS
PPSSVAHGPKQKENPSSRSAMRLRILRLGLRLEPRPLAILEDYADPFDVQETGEGPAGTS
GAPDKVPENDGYMEPYEAQKMMAEIRGSKETAAQPLPLYDTPYEPEEEGATPEGEGAPWP
RESRLPEDDERPPEEYDQPWEWKKERISKAFAVDIKVIKDLPWPPPVGQLDSSPSLPDGD
RDISGPASPLPEPSLEDGSAQFEGSEKSCLSPGREEKGRLPPRLSAGNPKSSKPLSVEPS
SPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSLSLKSSQ
GFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKLPIKGAEHMSLLYPVAIRTL

>Monodelphis domestica SHF
LAILEDYADPFDAQETGEGPAVPVGPTEKMPENDGYMEPYEAQKMMAGEHLGKGEQHKSG
NRFERLNFPRLEVPFFSSYCLTLAEIRGSKEAAAKPLPLYDTPYEPAEEGLSPEGEGTGR
PRESRLPEDDERPPEEYDQPWEWKKERISKAFAAQFEGSENCLSPSREEKGRPLPRLPGV
NSKTVKPLSIEPSSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSET
SKNDFSLSLKSSQGFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKLPIKGAEHM
SLLYPVAIRTL

>Ornithorhynchus anatinus SHF
MPENDGYMEPYEAQKMMAEIRGSKEPAPQLLPLYDTPYEPGEDGLSPEGEGGGRTREPRL
PAGDERPPEEYDQPWEWKKERISKAFAAQFEALDKGFLSPGREEKGRPLARLTKPVIGDP
TSPLGEWTDPALPLENQVWYHGAISRTDAEALLRLCKEASYLVRNSETSKNDFSLSLKSS
QGFMHMKLSRTKEHKYVLGQHSPPFASVPEIVHHYASRKLPIKGAEHMSLLYPVAIRTL

>Gallus gallus SHF
MEPYEAQKMMAEIRQKGLREAPSRPLHLYDTPYEPVSGGLDVDTDCPACPRPRESRLPED
DERPPEEYDQPWEWKKERISKAFAVEIKVIKDLPWPPPVGQLNSGETPPDGEASASVPPQ
HGPQSYEDANGPSEGLGYGRTSPCREEKARTALRHGTSSLKSTKTLSVEPGPFLGERIDP
ALPLESQCWYHGAISRTDAETLLRLCKEASYLVRNSETSKNDFSLSLKSSQGFMHMKLSR
TQENKYVLGQHSPPFDSVPEIIHHYASRKLPIKGAEHMSLLYPVAIRTL

>Taeniopygia guttata SHF
VLEDYADPFDAAQVAGSQAGLEKVMENDGYMEPYEAQKMMAGITQRPLFTPRVPDMCSSE
GSAQVGETVLLEGRALRKGLREAPARPLHLYDTPYEPVLDMDSDCSACPRPRESRLPEDD
ERPPEEYDQPWEWKKERISKAFAGEGWGTAAPRPAGRRRPRLNLKSTKTLTAEPGPFVGE
RIDPALPLESQCWYHGAISRTDAETLLRLCKEASYLVRNSETSKNDFSLSLKSSQGFMHM
KLSRTQENKYVLGQHSPPFDSVPEIIHHYASRKLPIKGAEHMSLLYPV

>Pelodiscus sinensis SHF
LLPWQVIVLEDYADPFDAKQAGGGQPGQEKVAENDGYMEPYEAQKMMAVSRGATWTVPGP
LPLAPRPPGSSQQELEATCEAGHMGTWHPQPWLPHTASCPPPRGAGTAPSPLTRSLCCLR
PVEIKVIKDLPWPPPVGQLDGGASPPDSEAPAQPSQPQHNHEDTSGLTWGTNRACLGPGR
WGPSRLPSPCCEAGLPPSILPGAKLQPDAPCPGSTPEPASLSPDSWYHGAISRTDAETLL
RLCKEASYLVRNSETSKNDFSLSLKSSQGFMHMKLSRTPENKYVLGQNSPLFDSVPRIIH
HYASHKLPIKGAEHMSLLYPVAIRTL

>Xenopus tropicalis SHF
MAKWIKEHLGFKSSKPPPPAPPKPDYRLCQAGGASTHHHHHHHLHSAVPQFPVTPAGQPD
ILAAYKLQKERDFEDPYTTCGAPGASAQLNSSTVPPSAPTSSSAQSPSSPSHSPDVKYVS
PKHRLIKVDTGEKGSCSPTGGNTAGSSGSPGQAFTSPSVPSPGVRSPPATAVAPQLEESK
QDKVAIVEDYADPFDAKQVPGSQNAPEKVTENDGYMEPYEAQKMMAEIRRRGSKELPCTP
LHLYDTPYEPSENGLDSEGEKSTSQRPRESRLPQDDERPPEEYDQPWEWKKERISKAFAA
QFDSADKTGMAAAKEDKLRHMHRHSAGNLKAIKHPSVEHCISVGERIDPSLPLESQFWYH
GAISRADAESLLRLCKEASYLVRNSETNKIDFSLSLKSSQGFMHMKLSRTKENKYVLGHN
SPPFNSVPEIIHHYASQKLPIKGAEHMSLLYPVAVRTL

>Danio rerio SHF a
KHTHTQQQHTHINAVVFFLGFAEIRGGRAPKDGPVRQLPLYDTPYEENGGEADAGLCSRE
SRLPQDDERPPEEYDQPWEWKKERISKAFAALLCYDCISDEDSSRGASRRDTHICRSSTV
QFDGVEKNRPLQRHSSACLVNMKTSSVDQSVGERIDPALPLEGQFWYHGAISRTDAEALL
RLCKEASYLVRNSETSKNDFSLSLKSSQGFMHMKLSRTKDSKYVLGQNSCLFDSVPEIIH
YYSSRKLPIKGAEHMSLLYPVAIRTL

>Takifugu rubripes SHF a
QSLLLSLEIRSGGRGPKEGSVRQLPLYDTPYEPAENGGDSDPEHPRVPRESRLPQDDERP
PEEYDQPWEWKKERISKAFAVQFDGVDKSRMSPTKDGKARPLQRHSGGCLVNTKMSSLDH
CSPSLAERIDPSMPLESQFWYHGAISRTDAESLLRLCKEASYLVRNSETSKNDYSLSLKS
SQGFMHMKLSRTKENKYILGQNSCPFDSVPEIIHFYSSRKLPIKGAEHMSLLYPVAIRTL

>Gasterosteus aculeatus SHF a
RSSALFAEIRSGGRGPKDGPARQLPLYDTPYEPAENGGDSDPEHPRCPRESRLPQDDERP
PEEYDQPWEWKKERISKAFAVQFDGVEKSRMSPTKEGKTRPLQRHSSGCLVNTKMSSLDH
GSSSLGERIDPSMPLESQFWYHGAISRTDAESLLRLCKEASYLVRNSETSKNDYSLSLKS
SQGFMHMKLSRTKESNYILGQNSGPFNSVPEIIHFYSSRKLPIKGAEHMSLLYPVAIKTL

>Oryzias latipes SHF a
FEAFRLRKIRSGGRGSKEGSLRQLPLYDTPYEPSENGGDSDPELLRCPRESRLPQDDERP
PEEYDQPWEWKKERISKAFAVQFDGVDKPRMSPTKDGKGRPLQRHSSGCLVNTKMTSLDH
CSSPVGERIDPSMPLESQFWYHGAISRTDAESLLRLCKEASYLVRNSETSKNDYSLSLKS
SQGFMHMKLSRTKENKYILGQNSCPFDSVPDIIHFYSSRKLPIKGAEHMSLLYPVAIRTL>Homo sapiens_SHB(ENSP_366936)
MAKWLNKYFSLGNSKTKSPPQPPRPDYREQRRRGERPSQPPQAVPQASSAASASCGPATA
SCFSASSGSLPDDSGSTSDLIRAYRAQKERDFEDPYNGPGSSLRKLRAMCRLDYCGGSGE
PGGVQRAFSASSASGAAGCCCASSGAGAAASSSSSSGSPHLYRSSSERRPATPAEVRYIS
PKHRLIKVESAAGGGAGDPLGGACAGGRTWSPTACGGKKLLNKCAASAAEESGAGKKDKV
TIADDYSDPFDAKNDLKSKAGKGESAGYMEPYEAQRIMTEFQRQESVRSQHKGIQLYDTP
YEPEGQSVDSDSESTVSPRLRESKLPQDDDRPADEYDQPWEWNRVTIPALAAQFNGNEKR
QSSPSPSRDRRRQLRAPGGGFKPIKHGSPEFCGILGERVDPAVPLEKQIWYHGAISRGDA
ENLLRLCKECSYLVRNSQTSKHDYSLSLRSNQGFMHMKLAKTKEKYVLGQNSPPFDSVPE
VIHYYTTRKLPIKGAEHLSLLYPVAVRTL

>Gorilla gorilla_SHB(ENSGGOP_13789)
PGSSLRKLRAMCRLDYCGGSGEPGGVQRAFSASSASGAAGCCCASSGAGAAASSSSSSGS
PHLYRSSSERRPATPAEVRYISPKHRLIKVESVAGGGAGDPLGGACAGGRTWSPTACGGK
KLLNKCAASAAEESGAGKKDKVTIADDYSDPFDAKNDLKSKAGKGESAGYMEPYEAQRIM
TEFQRQESVRSQHKGIQLYDTPYEPEGQSVDSDSESTVSPRLRESKLPQDDDRPADEYDQ
PWEWNRVTIPALAAQFNGNEKRQSSPSPSRDRRRQLRAPGGGFKPIKHGSPEFCGILGER
VDPAVPLEKQIWYHGAISRGDAENLLRLCKECSYLVRNSQTSKHDYSLSLRSNQGFMHMK
LAKTKEKYVLGQNSPPFDSVPEVIHYYTTRKLPIKGAEHLSLLYPVAVRTL

>Pongo abelii_SHB(ENSPPYP_21353)
LDYCGGSGEPGGVQRAFSASSASGAAGCCCASSGAGAAASSSSSSGSPHLYRSSSERRPA
TPAEVRYISPKHRLIKVESAAAGGAGDPLGGACASGRTWSPTACGGKKLLNKCAASAAEE
SGAGKKDKVIIADDYSDPFDAKNDLKSKAGKGESAGYMEPYEAQRIMTEFQRQESVRSQH
KGIQLYDTPYEPEGQSVDSDSESTVSPRLRESKLPQDDDRPADEYDQPWEWNRVTIPALA
AQFNGNEKRQSSPSPSRDRRRQLRAPGGGFKPIKHGSPEFCGILGERVDPAVPLEKQIWY
HGAISRGDAENLLRLCKECSYLVRNSQTSKHDYSLSLRSNQGFMHMKLAKTKEKYILGQN
SPPFDSVPEVIHYYTTRKLPIKGAEHLSLLYPVAVRTL

>Mus musculus_SHB(ENSMUSP_60433)
MAKWLNKYFSLGNSKTKSPPQPPRPDYREQRRRGERREQPPQAVPQACSASSASCGSAAA
CFSASSGSLPDDSGSTSDLIRAYRAQKERDFEDPYNGPGSSLRKLRAMCRLDYCGGGGGG
DPGGGQRAFTAAAGAAGCCCAAAGAGAAASSSSSSGSPHLYRSSSERRPTTPAEVRYISP
KHRLIKVESASAAGDPPGGVCSGGRTWSPTTCGGKKLLNKCSAEETGAGQKDKVTIADDY
SDPFDAKSDLKSKAGKGESAGYMEPYEAQRIMTEFQRQESVRSQHKGIQLYDTPYEPEGQ
SVDSDSESTVSLRLRESKLPQDDDRPADEYDQPWEWNRVTIPALAAQFNGNEKRQSSPSP
SRDRRRQLRAPGGGFKPIKHGSPEFCGILGERVDPTIPLEKQIWYHGAISRSDAENLLRL
CKECSYLVRNSQTSKHDYSLSLKSNQGFMHMKLAKTKEKYVLGQNSPPFDSVPEVIHYYT
TRKLPIKGAEHLSLLYPVAVRTL

>Rattus norvegicus_SHB(ENSRNOP_15338)
MAKWLNKYFSLGNSKTKSPPQPPRPDYREQRRRGERREQPPQAVPQACSASSASCGSAAA
CFSASSGSLPDDSGSTSDLIRAYRAQKERDFEDPYNGPGSSLRKLRAMCRLDYCGGGGDP
GGGQRAFTAAAGAAGCCCAAAGAGAAASSSSSSGSPHLYRSSSERRPATPAEVRYISPKH
RLIKVESAGAAGDPPGGVCSGGRTWSPTTCGGKKLLNKCAAEETGAGQKDKVTIADDYSD
PFDAKNDLKSKAGKGESAGYMEPYEAQRIMTEFQRQESVRSQHKGIQLYDTPYEPEGQSV
DSDSESTVSLRLRESKLPQDDDRPADEYDQPWEWNRVTIPALAAQFNGNEKRQSSPSPSR
DRRRQLRAPGGGFKPIKHGSPEFCGILGERVDPTIPLEKQIWYHGAISRSDAENLLRLCK
ECSYLVRNSQTSKHDYSLSLKSNQGFMHMKLAKTKDKYVLGQNSPPFDSVPEVIHYYTTR
KLPIKGAEHLSLLYPVAVRTL

>Canis familiaris_SHB(ENSCAFP_3477)
MAKWLHIRGSLGNSKTKSPPQPPRPDYREQRRRGERPSQAPQAVPQAPAGASASCGPTAA
SCFSTSSGSLPDDSGSTSDLIRAYRAQKERDFEDPYNGPGSSLRKLRAMCRLDYCGGGGE
PGGGQRAFSASSASGAAGCCCASSGAGAAASSSSSSGSPHLYRSSSERRPATPAEVRYIS
PKHRLIKVESAAGGAGDLPGGACSGGRTWSPTACGGKKLLNKCAASAAEESGAGKKDKVT
IADDYSDPFDAKNDLKSKAGKGESAGYMEPYEAQRIMTEFQRQESVRSQHKGIQLYDTPY
EPEGQSVDSDSESTVSPRLRESKLPQDDDRPADEYDQPWEWNRVTIPALAAQFNGNEKRQ
SSPSPSRDRRRQLRAPGGGFKPIKHGSPEFCGILGERVDPAVPPTGSRIYWYHGAISRGD
AENLLRLCKECSYLVRNSQTSKHDYSLSLKSNQGFMHMKLAKTKEKYVLGQNSPPFDSVP
EVIHYYTTRKLPIKGAEHLSLLYPVAVRTL

>Equus caballus_SHB(ENSECAP_5989)
MCRLDYCGGGGEPGGGQRAFSASSASGAAGCCCASSGAGAAASSSSSSGSPHLYRSSSER
RPATPAEVRYISPKHRLIKVESAAGGAGDPPGGACSGGRTWSPTASGGKKLLNKCAASAA
EESGAGKKDKVTIADDYSDPFDAKNDPKSKAGKGESAGYMEPYEAQRIMTEFQRQESVRS
QHKSIQLYDTPYEPEGQSVDSDSESTVSPRLRESKLPQDDDRPADEYDQPWEWNRVTIPA
LA

>Dasypus novemcinctus_SHB(ENSDNOP_17752)
MKLARGGREIRSLSGARRRRGCRSRGAAGRRRRRELELGVFSGRPGRPPPGPGRRGAWAA
ALSPGWPRRRTGLPRRGPRRPLAMAKWLNKYFSLGNSKTKSPPQPPRPDYREQRRRGERP
SQHPQAIPQAPASASCGPAAASCFSASSGSLPDDSGSTSDLIRAYRAQKERDFEDPYNGP
GSSLRKLRAMCRLDYCGGGGEPGGGQRAFSASSASGAAGCCCASSGAGAAASSSSSSGSP
HLYRSSSERRPATPAEVRYISPKHRLIKVESAACGGAGDSPGGACSGGRTWSPTACGGKK
LLNKCAASAAEESGAGKKDKVTIADDYSDPFDAKNDLKSKAGKGESAGYMEPYEAQRIMT
EFQRQESIRSQHKGIQLYDTPYEPDGQSFDSDSESTVSPRLRESKLPQDDDRPADEYDQP
WEWNRVTIPALAAQFNGSEKRQSSPSPSRDRRRQLRAPGGGFKPIKHGSPEFCGILGERV
DPAIPLEKQIWYHGAISRGDAENLLRLCKECSYLVRNSQTSRHDYSLSLK

>Gallus gallus_SHB(ENSGALP_41190)
MAKWLNKYFSLGNNKTKSPPQPPRPDYREKRNGAGGAPRPDGPPHLHRHQHHTSPGFPHR
HLRDDTSELLRAYRAQKDRDFEDPYSGPGSSLRKLRALCRPEPCAPDEPGPAAPRAFSSA
SCGAAASAPAGSPLLARSQSERRPGTPPEVRYISPRHRLIRVEIGDGGRFGRGGEQLAAS
APAKEKVLIADDYSDPFDAKSELNKMVKGENTGYMEPYEAQRIMTEFQKQEGMKTHQKNM
QLYDTPYEPEGSGVESDSESVVSQRLRESKLPQDDDRPADEYDQPWEWNKVTIPALAAQF
NGSEKRQASPSSSNDQRRQLRAPGRGFKPIKHGSPEFCGILGERIDPTVPLEKQIWYHGA
ISRTDAENLLRLCKECSYLVRNSQTSKHDYSLSLKSSQGFMHMKLTKTKEKYILGQNSPP
FDSVPEVIHYYTTKKLPIKGAEHLSLLYPVAVRTL

>Xenopus tropicalis_SHB(ENSXETP_32256)
MAKWLNKYFSLGNNNNNKSKSPPQPPRPDYKRNGGTERSFHLQYPGGQQQFYKHHTSPLP
GHCREESDLIRAYRAQKDRDFEDPYNGPGSSLRKLRAMCREEQQGEGRRGCTDGTNCFLQ
ESYHGGGSSTNTTSSSSSSSSSPHLYRSNSERRPAGAKQQLTGGSEHKYMVSPKHRLIKI
DSCGWGENGTGGGGAGTVGITWSPVVTPVTNKTEEQGNPGAKKEKVIIADDYSDPFDAKS
EQKIKGIKTENNGYMEPYEAQRLMTDIQKNESQKSLQKNIQLYDTPYEPESNGVESDSES
IVGLKLRESKLPQDDDRPADEYDQPWEWNKALPALAAQFNGGEKMQSLSPSNDRRRQLRA
PGGGFKPIKHGSPDVCGILGERVDPNIALEKQIWYHGAISRTDAENLLRLCKECSYLVRN
SQTSKHDFSLSLKSSQGFMHMKLSKTKEKYILGQNSPPFESVPEVVHFYTTRKLPIKGAE
HLSLLYPVPVRTL

>Homo sapiens_SHD(ENSP_446058)
MAKWLRDYLSFGGRRPPPQPPTPDYTESDILRAYRAQKNLDFEDPYEDAESRLEPDPAGP
GDSKNPGDAKYGSPKHRLIKVEAADMARAKALLGGPGEELEADTEYLDPFDAQPHPAPPD
DGYMEPYDAQWVMSELPGRGVQLYDTPYEEQDPETADGPPSGQKPRQSRMPQEDERPADE
YDQPWEWKKDHISRAFAVQFDSPEWERTPGSAKELRRPPPRSPQPAERVDPALPLEKQPW
FHGPLNRADAESLLSLCKEGSYLVRLSETNPQDCSLSLRSSQGFLHLKFARTRENQVVLG
QHSGPFPSVPELVLHYSSRPLPVQGAEHLALLYPVVTQTP

>Pan troglodytes_SHD(ENSPTRP_17511)
MAKWLRDYLSFGGRRPPPQPPTPDYTESDILRAYRAQKNLDFEDPYEDAESRLEPDPAGP
GDSKNPGDAKYGSPKHRLIKVEAADMARAKALLGGPGEELEADTEYSDPFDAQPHPAPPD
DGYMEPYDAQWVMSELPGRGVQLYDTPYEEQDPETADGPPSGQKPRQSRMPQEDERPADE
YDQPWEWKKDHISRAFAVQFDSPEWERTPGSAKELRRPPPRSPQPAERVDPALPLEKQPW
FHGPLNRADAESLLSLCKEGSYLVRLSETSPQDCSLSLRSSQGFLHLKFARTRENQVVLG
QHSGPFPSVPELVLHYSSRPLPVQGAEHLALLYPVVTQTP

>Gorilla gorilla_SHD(ENSGGOP_9982)
MAKWLRDYLSFGGRRPPPQPPTPDYTESDILRAYRAQKNLDFEDPYEDAENRLEPDPAGP
GDSKNPGDAKYGSPKHRLIKVEAADMARAKALLGGPGEELEADTEYSDPFDAQPHPAPPD
DGYMEPYDAQWVMSELPGRGVQLYDTPYEEQDPETADGPPSGQKPRQSRMPQEDERPADE
YDQPWEWKKDHISRAFAVQFDSPEWERTPGSAKELRRPPPRSPQPAERVDPALPLEKQPW
FHGPLNRADAESLLSLCKEGSYLVRLSETSHQDCSLSLRSSQGFLHLKFARTRENQVVLG
QHSGPFPSVPELVLHYSSRPLPVQGAEHLALLYPVVTQTP

>Mus musculus_SHD(ENSMUSP_47656)
MAKWLRDYLNLGSRRPPPQPPTPDYTESDILRAYREQKDLDFEDPYEDSNGRAEPEVTGS
GDPKYNSPRHRLIKVEAADMARAKALLGSPGEEQPEAETEYSDPFDAQPQPPAPNSGYME
PYDARSVSSEQPSRAVQLYDTPYEEQATKPEDGGSSGQSRRPLEDERPADEYDQPWEWKK
DHISRAFAVQFDGPDWERTPCSTKEPWRPQPAERVDTALALEKQPWFHGPLSRAEAENLL
SLCKEGSYLVRLSETRAQDCILSLRSNQGSMHLKFARTRENQVVLGQHSGPFPSIPELVL
HYSARPLPVQGAEHLALLYPVTSSQSSQGPCTLAAKPERGQGDP

>Rattus norvegicus_SHD(ENSRNOP_65655)
MAKWLRDYLNLGSRRPPPQPPTPDYTESDILRAYREQKDLDFEDPYEDSNGRPESEITES
SDPKYNSPRHRLIKVEAVNLARAKTLLGSLGEEPEADTEYSDPFDAQPQPPAPNNGYMEP
YDARNISSEQPSRAVQLYDTPYEEQDMKPEDGGSSGQSRRPLEDERPADEYDQPWEWKKD
HISRAFAVQFHGPDWERTPCSTKEPWRPQPAERVDTALALEKQPWFHGPLSRVEAENLLS
LCKEGSYLVRLSETRAQDCILSLRSNQGSMHLKFAKTRENQVVLGQHSGPFPSVPELVLH
YSARPLPVQGIEHLALLYPVTSSQSSQGPCTLAARPEKGQGDP

>Canis familiaris_SHD(ENSCAFP_40130)
SFGVTHAQMAKWLRDYLSFGGRRPPPQPPTPDYTESDILRAYREQKDLDFEDPYEDSDSR
LEPDPAGPGDCKGPGDAKYDSPKHRLIKVEAADMARDLSHSPSEPWSTLNHDAPPGVPQG
CVGQCLGGQRKEGGPHPPPSDDGYMEPYDAQRADLPCKGVQLYDTPYEEQDQDPGDGAPS
GRRPRQSRLPQEDERPADEYDQPWEWKKDHISKAFAGAPPPQALTLPPQALSVHVLPLSA
LFDSPEWERTPGSAKELRRPPSRSPQAAERVDPALPLEKQPWFHGPLSRADAENLLSLCK
AGSYLVRLSETSPQDCSLSLRSSQGFLHLKFARTRESQFVLGQHSGPFASVPELVLHYSS
RPLPVQGAEHLALLYPVVTQTP

>Equus caballus_SHD(ENSCAFP_40130)
MEPYDAQWVVSELPCRGVQLYDTPYEEQDREPGDGPPSGRRPRQSRLPPEDERPADEYDQ
PWEWKKDHISKAFAVQFDSPEWERTSGSAKELRRPPPRSPQPAERVDAALPLEKQPRNPR
GLPWSDPACPRPQGVWFHGPLSRADAESLLSLCKEGSYLVRLSETSPQDCSLSLRSSQGF
LHLKFARTRENQFVLGQHSGPFASVSELVLHYSSRPLPVQGAEHLALLYPVGTQTP

>Loxodonta africana_SHD(ENSLAFP_7839)
MAKWLRDYLSFGGRRPPPQPPTPDYSESDILRAYRAQKNLDFEDPYEDADSRLEPDPAGT
GDPKGPGDTKYDSPKHRLIKVEAADMAKAKALLGSPGEEPEADTEYSDPFDAQPHLPPPD
DGYMEPYDAQRVVSELPGRGVQLYDTPYEEEDQEPGDEPPSGGQKPRQSRLPQEDERPAD
EYDQPWEWKKDHISRAFAVQFDSPDWERTPGLAKELRRPLPRSPQPAERVDPTLPLEKQP
IPWFLGESHMASVPPPPASSSLCLSCFLILRSEHXSPQDCSLSLRSSQGFLHLK

>Tetraodon nigroviridis_SHD(ENSTNIP_20327)
MAKWLKLNFGSKRDPPQPPRPDYTESEILRAYRAQKELDFEDPYQHTDKEHQNGGFSPAL
SLPSFPAFGSVLPNGMEVKVVSPKHRLIKVDSQEFGRCKVPLSPTAVQEEPVIPSAPSAL
EGDADYSDPFDVRPDPRGRPHWETKPASTDCCSYMEPFEAQRILSEMQHSKKTNRSGSGD
GGQLYDNPYEERTRQPRQAAPPAQQAHWVEAARVQVDSRESRLPQDDERPADEYDQPWEW
KKDDISKALAVQFEGAERERSWAQTEQTRFSKAGNATSSVDSTTLRLVGDTPPRLGERVD
PSVPLERQVWYHGTLSRSEAEGLLTLCKESSYLVRNSQTGRNDYSLSLRSCKGFMHMKFS
LSADGRYVLGENSPPFGTIPEVIHYYTTHKLPIRGAEHMSLLYPVIVQTL

>Gasterosteus aculeatus_SHD(ENSGACP_12944)
MAKWLKDYLNFGTRRDPPQPPRPDYSESEILRAYRAQKELDFEDPYQHSEKEHQNGGFSP
RSATVKVVSPKHRLIKVDSQELVRCLLLLCPQQAALDADTDYSDPFDVCPEPRGRQNWEP
KPASTDYCSYMEPFEAQRIISGLLSGSADGVQLYDNPYEERPRPYYRAAPAAQQQTPRVE
LGLPDSRESRLPRDDERPADEYDQPWEWKKDNISKALAAIVQFEGAERERSRVDSTTFPL
IGDTPPLLGERVDPTMPLERQVWYHGALSRSEAESLLTLCKESSYLVRNSQTCRNDYSLS
LRSCKGFMHMKFTRSAERRYVLGENSPPFSTIPEVIHYYTTHRLPIRGAEHMSLLYPVIV
QTL

>Homo sapiens_SHE(ENSP_307369)
MQWSPTPGASACLGWASSLACSTAPTLLGRAGRGPLMAAKWFKEFPLNLKTVSERAKPGG
GGGKLRKNSEAGGAGPGPGKGRKNSAAELGSGRAGVGPKDSRLSRDSLQGLIQAAAGKGR
KNSRATEEEPHRGATKSSGCSTYINRLIKVDTQEKNGKSNYPSSSSSSSSSSSSASSSPS
SLGPELDKGKIIKQQETVIILEDYADPYDAKRTKGQRDAERVGENDGYMEPYDAQQMITE
IRRRGSKDPLVKALQLLDSPCEPADGGLKSETLAKRRSSKDLLGKPPQLYDTPYEPAEGG
PRAEGKARPPDSRLPENDERPAAEYEQPWEWKKEQIVRALSVQFEGAERPSFREETVRQH
HRQKSWTQKILKPALSDHSEGEKVDPGLPLEKQPWYHGAISRAEAESRLQPCKEAGYLVR
NSESGNSRYSIALKTSQGCVHIIVAQTKDNKYTLNQTSAVFDSIPEVVHYYSNEKLPFKG
AEHMTLLYPVHSKLH

>Pan troglodytes_SHE(ENSPTRP_2336)
MQWSPTPGASACLGWASSLACSTAPTLLGRAGRGPLMAAKWFKEFPLNLKTVSERAKPGG
GGGKLRKNSEAGGAGPGPGKGRKNSAAELGSGRAGVGPKDSRSSPSSLGPELDKGKIIKQ
QDTVIILEDYADPYDAKRTKGQRDAERVGENDGYMEPYDAQQMITEIRRRGSKDPLVKAL
QLLDSPCEPADGGLKSETLAKRRSSKDLLGKPPQLYDTPYEPAEGGPRAEGKARPPDSRL
PENDERPAAEYEQPWEWKKEQIVRALSVQFEGAERPSLREETVRQHHRQKSWTQKILKPA
LSDHSEGEKVDPGLPLEKQPWYHGAISRAEAESRLQPCKEAGYLVRNSESGNSRYSIALK
TSQGCVHIIVAQTKDNKYTLNQTSAVFDSIPEVVHYYSNEKLPFKGAEHMTLLYPVHSKL
H

>Gorilla gorilla_SHE(ENSGGOP_15395)
MQWSPTPGASACLGWASSLACSTAPTLLGRAGRGPLMAAKWFKEFPLNLKTVSERAKPGG
GGGKLRKNSEAGGAGPGPGKGRKNSAAELGSGRAGVGPKDSRLSRDSLQGLIQAAAGKGR
KNSRATEEEPHRGATKSSGCSTYINRLIKVDTQEKNGKSSYPSSSSSSSSSSSSASSSPS
SLGPELDKGKIIKQQDTVIILEDYADPYDAKRTKGQRDAERVGENDGYMEPYDAQQMITE
IRRRGSKDPLVKALQLLDSPCEPADGGLKSETLAKRRSSKDLLGKPPQLYDTPYEPAEGG
PRAEGKARPPDSRLPENDERPAAEYEQPWEWKKEQIVRALSVQFEGAERPSVREETVRQH
HRQKSWTQKILKPALSDHSEGEKVDPGLPLEKQPWYHGAISRAEAESRLQPCKEAGYLVR
NSESGNSRYSIALKTSQGCVHIIVAQTKDNKYTLNQTSAVFDSIPEVVHYYSNEKLPFKG
AEHMTLLYPVHSKLH

>Pongo abelii_SHE(ENSPPYP_908)
MQWPPTPGASACLGWASSLACSTAATLLGRAGRGPLMAAKWFKEFPLNLKTVSERAKPGG
GGGGKLRKNSEAGGAGPGPGKGRKNSAAELGSGRAGVGPKDSRLSRDSLQGLIQAAAGKG
RKNSRATEEEPHRGATKSSGCSTYINRLIKVDTQEKNGKSNYPSSSSSNSSSSSSASSSP
SSLGPELDKGKIIKQQDTVIILEDYADPYDAKRTKGQRDAERVGENDGYMEPYDAQQMIT
EIRRRGSKDPLVKALQLLDSPCEPADGGLKSETLAKRRSSKDLLGKPPQLYDTPYEPAEG
GPRAEGKARPPDSRLPENDERPAAEYEQPWEWKKEQIVRALSVQFEGAERPSVREETVRQ
HHRQKSWTQKILKPALSDHSEGGKVDPGLPLEKQPWYHGAISRAEAESRLQPCKEAGYLV
RNSESGNSRYSIALKTSQGCVHIIVAQTKDNKYTLNQTSAVFDSIPEVVHYYSNEKLPFK
GAEHMTLLYPVHSKLH

>Mus musculus_SHE(ENSMUSP_59658)
MRRPPAPGAPRCLSWASSLFCSAASTLPGPLMAAKWFKEFPLTLKTASERARPGGAGGKP
RKNSETGGAAPTPGKGRKNSAAELGASKASSGPPKDSRLSRDSLQGLIQAAAGKGRKNSR
VTATATEEEPHRGAVTKSAGCSTYISRLIKVDTQEKNGKSAYPGGGSTSSSSSSSSSASS
SPSSLGPELDKAKIMRQQDTVIILEDYADPYDAKRTKGQRDAERVGENDGYMEPYDAQQM
ITEIRRRGSKDPLVKALQLLDGPSEPGETVKVEATAKRRSSKDLLGKPPQLYDTPYEPSE
GGQRVAEVKTRPADSRLPEEDDRPAAEYEQPWEWKREQIARALSVQFEGSDRPPGREDAG
RPHHWQKTLKPTLSDHGDGEKVDPGLALEKQPWYHGSISRAEAESRLQPCKEAAYLVRNS
ESGNSKYSIALKTSQGCVHIIVAQTKDNKYTLNQTSAVFDSIPEVVHYYSNAKLPFKGAE
HMTLLHPVHKLH

>Rattus norvegicus_SHE(ENSRNOP_28225)
MAAKWFKEFPLTLKTASERARPGGAGGKPRKNSETGSAAPTPGKGRKNSAAELGGSRTGS
GPPKDSRLSRDSLQGLIQAAAGKGRKNSRVTTTATASASATTTEEEPHRGAVAKSAGCST
YISRLIKVDTQEKNGKSIYPGGGSTSSSSSSSSSASSSPSSLGPELDKTKIMRQQDTVII
LEDYADPYDAKRTKGQRDAERVGENDGYMEPYDAQQMITEIRRRGSKDPLVKALQLLDGP
CEPGETMKVEATAKRRSSKDLLGKPPQLYDTPYEPSEGDLRAAEVKARPADGRLPEEDDR
PAAEYEQPWEWKREQIARALSVQFEGSDRSPGREEAGRPQHWQKTLKPTLSDHGDGEKVD
PGLALEKQPWYHGSISRAEAESRLQPCKEAGYLVRNSESGNSKYSIALKTSQGCVHIIVA
QTKDSRYTLNQTSAVFDSIPEVVHYYSTAKLPFKGAEHMTLLHPVHKLH

>Canis familiaris_SHE(ENSCAFP_25299)
MAARWFKEFPLNLKTASERARPGGGGGRLRKNSEAGGAGPAPGKGRKNSAAELGSGRAGV
GAPRDSRPPRESLQGLIQAAAGKGRKNSRAADDEQHRGVARSAGCSSYIGRLVKVDAQEK
SGKSSASSTSSCSSSASSSPASLGPELDKGKIGRQPETVIILEDYADPYDAKRTKGQRDA
ERAGENDGYMEPYDAQQMITEIRRRGSKDPLVKALQLLEGACELGENSAKTETLAKRRSS
KELLGKPPQLYDTPYEPADAAPDRRARLPVEDERPAAEYEQPWEWKKEQIARALSVQFEG
SDRPSVKEDTVKQHQRQKSWTQKILKPAASDHSEGERVDPALPLGKQPWYHGAITRAEAE
SRLQPCKEAGYLVRNSESGNSKYSIALKTSQGCVHIIVAQTKDNKYTLNQTSAVFDSIPE
VVHYYSNEKLPFKGAEHMSLLHPVHSKLH

>Dasypus novemcinctus_SHE(ENSDNOP_20073)
MQWSPAPGASAYLGWASSLACSAATTLLSRAGRAPLMAAKWFKEFPLNLKTVSERAKPGG
GGGGKLRKNSEAGGAGPTPGKGRKNSAAELGGGRAGGGPPKDSRLSRDSLQGLIQAAAGK
GRKNSRATEEEPHRGATKSSGCSTYINRLIKVDTQEKNGKSNYPSSSSSSSSSSSSSASS
SPSSLGPELDKGRITKQQDTVIILEDYADPYDAKRTKGQRDAERVGENDGYMEPYDAQQM
ITEIRRRGSKDPLVKALQLLEGPCEPGENGMKPEALVRRRSSKDLLGKAPQLYDTPYEPP
EAGPRAEGPTGAERKARPPDSRLPENDERPAAEYEQPWEWKKEQIVRALSVQFEGSERPA
AREEAVRQHHRQKSWTQKILKPTLSDHSEGERVDPALPLEKQPWYHGAITRAEAESRLQP
CKEAGYLVRNSESGNSRYSIALKTSQGCVHIIVAQTKDNKYTLDQTSAVFDSIPEVVHYY
SNEKLPFKGAEHMTLLYPVLNKLH

>Taeniopygia guttata_SHE(ENSTGUP_4179)
SRLPRDNLQGLLQAATGKMRKNSRVEGGTAEGPSKTYINRLIKVEASEKNGKGHPGPLPA
GLPAPEQDKGKPPKTETPDPRAHLLVKQRLVIILEDYADPYDAKRTKGQRDAERLGENDG
YMEPYDAQQMITEIRRRGSKDPLFKAILLLDGPGEPGEGGAKMDLAKRLGGKEVAGKGPQ
LYDTPYEPGEGVAGGTPERRVRASDGRLPENDERPAGEYEQPWEWKKEQIVKALSVQFEG
SERPKEETVRQHLRQKSWTPKMLKPAGTEHSEGERVDPALALEKQPWYHGAITRAEAESR
LQPCREAGYLVRTSESGSGKYSIALKTSQGCVHIITKDNKYTLSQASGVFASIPEVVHYY
STEKLPFKGAEHMALLHPVHCKLH

>Xenopus tropicalis_SHE(ENSXETP_49681)
VREPPGAPRPVWESYLPITVCWFLLPAMAKWFKDLPLTLKNVSDRAKPGLPGAKTLPKAG
ASRKNSCPEPSGPTGAPVKSRKNSSSEGQSKSLKDTRLSRESLQSLLQGKGRKNSRDEGG
GLRAPKGHSTYINRLIKVDPSLQDKNSRDIQETEEQPPEKDQDRPIKDETIIIIENYAIP
YDAKCTKDPRDAERLGENDGYMEPYDAQQMITEIRRRGSKDNLITELLLLELGPPCGLKT
VVRRPGSQELLDRAPQLYDTPYEPPDAGGEAEPQENKGSAGDGTRPENDERPAGEYEQPW
EWKKEHIVRALSVQFENSERSPSKEEPGRSHQRQKSWTPKVLKQHQAEQGDKVDPTVPLE
KQSWYHGSVTRDQAESLLDSCPEASYLLRNSGSGNSKYSIALKTSQGCVHIIVAQTKNNK
FTLSQMCGAFNSIPEVVHHYSSQKLPFKGSKHISLLHPVPSKPH

>Danio rerio_SHE(ENSDARP_118971)
MAKWFKDFPTSLKTGSDRIRSASESGTQSRPKPVLTVGTGSKGSLRKNSGAENGGGGGGV
GSLLHGRNRKNSAIELGRNHSSTGSMKDGKIWEILIPGKSKKNTKMEGFEDHRTLRTTSL
ADEYMSRMIKVNDPKSSPGGSSPDSERAKSPIRTEPIIVEDYADPFDAEKTREQKEAERE
GENDGYMEPYDAQLIITEIRRRGSKDLLKVCVVLNGGEGEGSGPPQIYDVPYEEVLEGIP
LTRPESDSRPPAEYELPWEWKKEQIVRALSAQFDGAERMSKEESGSPTIKQQTLRHKSWT
TKSLRPNPPSPTSPSSPSITPDSETPIVDPTLPLEKQSWYHGSVSRQEAEAQLQQCREAS
FLVRDSESATSKYSIALKTSQGCVHIIVAQTKECGYTLEKSSCVFPSIPEVVHHYCTQRL
PFTGAEHMTLQHPVPRTH

>Takifugu rubripes_SHE(ENSTRUP_13632)
MAKWFRDFPINLKNGTERVRSASESGPPSRSKPSFSRDSLKVNPRKDGGMGGLLVGRNRK
NSASELGRNSPSSGGTVWDSLTSGKGRKNAKIDTGTLDENRQVRTSSLAQAYISRMIKVD
KQDKTPKLSGICEQKQHENEKGRPDIKTTTDNSFFLNKQNQLIILEDYADPFDAEKTKEQ
REAERAGVNDGYMEPYDAQVIITEVRRRGSKDLLKVCVLLDRGQKEGKGEEGKPVPLNIY
DTPYEGELEGDREGVWIPVTRPESDVRPAGEYELPWEWRKEDIVRVLSAQFEAMDCSQIR
QQPQQQQHQHTLRQKNWNHKTLSPSAPLDGETAKVDPSLPLEKQSWYHGSVSRQQAEAQL
QRCREASFLVRDSESGTSKYSIALKTSQSCVHIIVAQTKSVKGLGFTLDQSSCVFPSIPE
LVHHYCTHRLPFTGAEHMTLQHPVHRMH

>Tetraodon nigroviridis_SHE(ENSTNIP_21502)
LIILEDYADPFDAEKTKEQREAERAGVNDGYMEPYDAQVIITGERGSKDLLKVCVLLDRG
QREGKREEGHPLPLNIYDTPYEGELDGDREGVWIPVTRPESDIRPPGEYELPWEWRKEDI
VRALSVPHRMGRWLKWTPASPWRSRGEVGGEGSWYHGSVSRQQAEAQLQRCREASFLVRD
SESGTSKYSIALKTSQSCVHIIVAQTKGVKGLGFTLDQSSCVFPSIPELVHHYCTHRLPF
TGAEHMTLQHPVH

>Gasterosteus aculeatus_SHEa(ENSGACP_5924)
YRRPPGPASPPNFRYPRSLFCQIGMRFPSQVAMAKWFKEFPINLKNGADRIRSASESGSQ
PKATKTGPVASIGTKTAGSKTGHRKNTSGDHTNRKNSELSRNGTISLKDGKVWENFLSGK
SRKNSKAEPAVEEPHRPLKSSQSANGFINRLIRVDKQDKTPNFNSATITNHQVAPEAEKP
AQCKSEAVSVRSKRVLIQVIILEDYADPFDAQKTREQREAERVGENDGYMEPYDAQQMIT
EIRRRGSKDLLKVCVEAGEGTGEDGQPVPLQIYDVPYKGGGEGDKAAVTPPERDSRPPTE
YELLWEWRKEPVIKTLSVEFISSLVSPPAQFDSPEHQTKAPAPSCALDAEARCVDPCLPL
EKQSWYHGCVTRQEAEFLLQPCREASFLVRNSESDSSKYSIALKTSQGCVHIIVAQTKEN
GYTLDQSSCVFANIPEVVHHYCSRRLPFDGAEHMTLLHPVPRPH

>Gasterosteus aculeatus_SHEb(ENSGACP_16031)
MARWFRDFPINLKNGNERVRSASESGPPRNQRKDGGVGGLLAGRNRKNSVEFGRNNAGCG
GTVWDTLTPGKGRKNAKVEAGTSDENRQVRTTSLAQAYISRMIKVDKQDKTPKLNGITEH
KQLGNETGRPDIKTTTLADPSTLPALLSPGKSCSQLIILEDYADPFDAEKTKGQREAERA
GVNDGYMEPYDAQVIITEVRRRGSKDLLKVCVLLDRGHREGKEEERKHPPPNIYDTPYEG
GLEGDSGGVWIPVTRPESDVRPAGEYELPWEWRKEDIVRALSAQFEAVDCSPTKENGSIP
PRQQHQQQQLTLSAPLDGETAKVDPSLLLEKQNWYHGSVSRQQAEAQLQRCREASFLVRD
SESGTSKYSIALKTSQSCVHIIVAQTKSAKGLGFTLDQSSCVFSSIPELVHHYCTHRLPF
TGAEHMTLQHAVPRPH

>Oryzias latipes_SHE(ENSORLP_12147)
MAKWFKDFPINLKNGNERVRSASESGGNQRKDGGVGSLLTGRNRKNSATELGRNNSGYGG
TVWDSLTNGKGRKNSKVEPGASDENRQVRTSSLAQAYISRMIKVDKQDKTPKVNGGTEQK
QHDNDNGKADIKTAVSTKKSQTKSKVVRRGKKLIILEDYADPFDAEKTKEQREAERAGVN
DGYMEPYDAQVIITDVRRRGSKDLLKVCVLLDRGQKEVKGGDEGTQSPPIIYDTPYEGGL
EGHSEGVWIPVTRPESDIRPAGEYELPWEWRKEDIVRALSAQFETVDCSLGKENSSTSGR
QQQQTLRQRNWTNKALVSTSSSDGETPKVDSSLPLEKQSGLPSWYHGSVSRQQAEAQLQR
CRDASFLVRDSESGTSKYSIALKTSQSCVHIIVAQTKSSKGLGYTLDQSSCVFPSIPELV
CHYCTHRLPFTGAQHMTLQHPVPKPH

>Homo sapiens_SHF(ENSP_290894)
MQQEGGPVRSAPCRTGTLEGSRQGSPGHRKRASPKGSLSSAQPHSWMLTPSPLNSHCAHR
EPISSSPQPVANGPKQKKKSNWRSTTRLRIIRLRDRLEPRPLAILEDYADPFDVQETGEG
SAGASGAPEKVPENDGYMEPYEAQKMMAEIRGSKETATQPLPLYDTPYEPEEDGATAEGE
GAPWPRESRLPEDDERPPEEYDQPWEWKKERISKAFAVDIKVIKDLPWPPPVGQLDSSPS
LPDGDRDISGPASPLPEPSLEDSSAQFEGPEKSCLSPGREEKGRLPPRLSAGNPKSAKPL
SMEPSSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSLS
LKSSQGFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKLPIKGAEHMSLLYPVAI
RTL

>Gorilla gorilla_SHF(ENSGGOP_12058)
MVAQSLSDAHHALAIMLSERLWLGLELLNFSRRKISSDPPPYNFLEAREAALGHRWRMQQ
EGGPVRSAPCRTGTLEGSRQGSPGHRKRASPKGSLSSAQPHSWMLTPSPLNSHCAHRESI
SSSPQPVANGSKQKKKSNWRSTTRLRVIRLRDRLEPRPLAILEDYADPFDVQETDEGSAG
ASGAPEKVPENDGYMEPYEAQKMMAEIRGSKETATQPLPLYDTPYEPEEDGATPEGEGGP
WPRESRLPEDDERPPEEYDQPWEWKKERISKAFAVDIKVIKDLPWPPPVGQLDSSPSLPD
GDRDISGPASPLPEPSLEDSSAQFEGPEKSCLSPGREEKGRLPPRLSAGNPKSAKPLSME
PSSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSLSLKS
SQGFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKLPIKGAEHMSLLYPVAIRTL

>Pongo abelii_SHF(ENSPPYP_7299)
MQQEGGPVRSAPCRPGTLAGSRQGSPGHRKRASPKGSLSSAQPHSWMLTPSPLNSHCAHR
EHISSSPPPVANGPKQKKKSNWRSTTRLRVIRLSDRLEPRPLAILEDYADPFDVQETGEG
SAGASGAPEKVPENDGYMEPYEAQKMMAEIRGSKETATQPLPLYDTPYEPEEDGATPEGE
GAPWPRESRLPEDDERPPEEYDQPWEWKKERISKAFAVDIKVIKDLPWPPPVGQLDSSPS
LPDGDRDISGPASPLPEPSLEDSSAQFEGPEKSCLSPGREEKGRLPSRLSAGNPKSAKPL
SMEPSSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSLS
LKSSQGFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKLPIKGAEHMSLLYPVAI
RTL

>Macaca mulatta_SHF(ENSMMUP_11471)
EAALGHRWRMQEGGPLRSAPCRPGTLHGSRQGSPGHTKWAFPKASLSSAQPHSWMLTRSP
LNFHCAHREPRSSSPPPVANGPKQRKKSNWRSTTRLRVIRLSDRLEPRPRTILEDYADPF
DVQETGEGSAGASGAPEKVPENDGYMEPYEAQKMMAEIRGSKETATQPLPLYDTPYEPEE
DGATPEGEGAPWSRESRLPEDDERPPEEYDQPWEWKKERISKAFAVDIKVIKDLPWPPPV
GQLDSSPSLPDGDRDISGPASPLPEPSLEDSSAQFEGSEKSCLSPGREEKGRLPPRLSAG
NPKSAKPLSVEPSSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSET
SKNDFSLSLKSSQGFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKLPIKGAEHM
SLLYPVAIRTL

>Mus musculus_SHF(ENSMUSP_119980)
MEPYEAQKMMAEIRGSKETAAQPLPLYDTPYEPEDEGASPEGEGTPWPRESRLPEDDERP
PEEYDQPWEWKKERISKAFAAQFEGSENCLSPGREEKGRLPPRLSAGNPKSAKPLGMEPS
SPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSLSLKSSQ
GFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKLPIKGAEHMSLLYPVAIRTL

>Rattus norvegicus_SHF(ENSRNOP_59526)
MEPYEAQKMMAEIRGSKETAVQPLPLYDTPYEPEDEGASLEGEGAPWPRESRLPEDDERP
PEEYDQPWEWKKERISKAFAVDIKVIKDLPWPPPVGQLDSSPSLPDGDRDISGPASPLPE
PSLEDSSAQFEGSEKNCLSPGREEKGRLPPRLSAGNPKTAKPLGAEPSSPLGEWTDPALP
LENQLVPRGHQPNRCREPAQAVQRGQLPGAQQ

>Canis familiaris_SHF(ENSCAFP_20218)
LFFLGYFPVRRPWGKGGVQALGTQTCEVPRVSCELGRGTDGDRCAPTGARVGTRGGLTFG
PGFASPALGVAHFLPVCPHPLEARTPPPPRQGEADPDRERNPAPPLLPTSPAPPPPGGAP
PPHPPPAGRRAPRAPLAQSGWPHVTERSSPGGLRPGAAGAGEPGERPGGVAPGPGGAGAG
PGGGGSGGVSKWLREHLGFRGGGGGGGGGKPAPPEPDYRPPAPSPAAPPAPPPDILAAYR
LQRERDFEDPYSGGPSSSAAAPATPTAPGPTPPPRHGSPPHRLIRVETPGPPAPPPEERI
SGPPAGSDRLAILEDYADPFDVQETGEGPAGASGAPEKVPENDGYMEPYEAQKMMAEIRS
SKETAAQPLPLYDTPYEPEEEGTTPEGEGTPWPRESRLPEDDERPPEEYDQPWEWKKERI
SKAFAVDIKVIKDLPWPPPVGQLDSSPSLPDGDRDISGPASPLPEPSLEDSSAQFEGSEK
SCLSPGREEKGRLPPRLSAGNPKSAKPLGMEPSSPLGEWTDPALPLENQVWYHGAISRTD
AENLLRLCKEASYLVRNSETSKNDFSLSLKSSQGFMHMKLSRTKEHKYVLGQNSPPFSSV
PEIVHHYASRKLPIKGAEHMSLLYPVAIRTL

>Bos taurus_SHF(ENSBTAP_27883)
MLLSGAPPAGXPAPPPDILAAYRLQRERDFEDPYSGGPSGTATLATPSAPGPTPPPRHGS
PPHRLIRVETPGPPAPPPEERISGHPASSDRLAILEDYADPFDVQETGEGPIGAAGAPEK
VPENDGYMEPYEAQKMMAEIRGSKETAAQPLPLYDTPYEPEEEGATPEGEGAPWPRESRL
PEDDERPPEEYDQPWEWKKERISKAFAAQFEGSEKSCLSPGREEKGRLPPRLSAGNPKSA
KPLSMEPSSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDF
SLSLKSSQGFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKLPIKGAEHMSLLYP
VAIRTL

>Dasypus novemcinctus_SHF(ENSDNOP_25561)
YRPPAPNPAAPPAPPPDILAAYRLQRERDFEDPYSGGPSGSAALATPTAPGPTPPPRHGS
PPHRLIRVETPGPPAPPPEERISGPPASSDRLAILEDYADPFDVQESGEGTAGASGAPEK
IPENDGYMEPYEAQKMMAEIRGSKETGAQPLPLYDTPYEPEEEEATPESEGAPWPRESRL
PEDDERPPEEYDQPWEWKKERISKAFAAQFEGSEKSCLSPGREEKGRLPPRLSAGNPKPA
KPPSVEPSSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSGTSKNDF
SLSLKSSQGFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKLPIKGAEHMSLLYP
VAIRTL

>Ornithorhynchus anatinus_SHF(ENSOANP_9177)
MPENDGYMEPYEAQKMMAEIRGSKEPAPQLLPLYDTPYEPGEDGLSPEGEGGGRTREPRL
PAGDERPPEEYDQPWEWKKERISKAFAAQFEALDKGFLSPGREEKGRPLARLTKPVIGDP
TSPLGEWTDPALPLENQVWYHGAISRTDAEALLRLCKEASYLVRNSETSKNDFSLSLKSS
QGFMHMKLSRTKEHKYVLGQHSPPFASVPEIVHHYASRKLPIKGAEHMSLLYPVAIRTL

>Gallus gallus_SHF(ENSGALP_3993)
MEPYEAQKMMAEIRQKGLREAPSRPLHLYDTPYEPVSGGLDVDTDCPACPRPRESRLPED
DERPPEEYDQPWEWKKERISKAFAVEIKVIKDLPWPPPVGQLNSGETPPDGEASASVPPQ
HGPQSYEDANGPSEGLGYGRTSPCREEKARTALRHGTSSLKSTKTLSVEPGPFLGERIDP
ALPLESQCWYHGAISRTDAETLLRLCKEASYLVRNSETSKNDFSLSLKSSQGFMHMKLSR
TQENKYVLGQHSPPFDSVPEIIHHYASRKLPIKGAEHMSLLYPVAIRTL

>Xenopus tropicalis_SHF(ENSXETP_16922)
MAKWIKEHLGFKSSKPPPPAPPKPDYRLCQAGGASTHHHHHHHLHSAVPQFPVTPAGQPD
ILAAYKLQKERDFEDPYTTCGAPGASAQLNSSTVPPSAPTSSSAQSPSSPSHSPDVKYVS
PKHRLIKVDTGEKGSCSPTGGNTAGSSGSPGQAFTSPSVPSPGVRSPPATAVAPQLEESK
QDKVAIVEDYADPFDAKQVPGSQNAPEKVTENDGYMEPYEAQKMMAEIRRRGSKELPCTP
LHLYDTPYEPSENGLDSEGEKSTSQRPRESRLPQDDERPPEEYDQPWEWKKERISKAFAA
QFDSADKTGMAAAKEDKLRHMHRHSAGNLKAIKHPSVEHCISVGERIDPSLPLESQFWYH
GAISRADAESLLRLCKEASYLVRNSETNKIDFSLSLKSSQGFMHMKLSRTKENKYVLGHN
SPPFNSVPEIIHHYASQKLPIKGAEHMSLLYPVAVRTL

>Danio rerio_SHF(ENSDARP_134206)
KHTHTQQQHTHINAVVFFLGFAEIRGGRAPKDGPVRQLPLYDTPYEENGGEADAGLCSRE
SRLPQDDERPPEEYDQPWEWKKERISKAFAALLCYDCISDEDSSRGASRRDTHICRSSTV
QFDGVEKNRPLQRHSSACLVNMKTSSVDQSVGERIDPALPLEGQFWYHGAISRTDAEALL
RLCKEASYLVRNSETSKNDFSLSLKSSQGFMHMKLSRTKDSKYVLGQNSCLFDSVPEIIH
YYSSRKLPIKGAEHMSLLYPVAIRTL

>Takifugu rubripes_SHF(ENSTRUP_8175)
QSLLLSLEIRSGGRGPKEGSVRQLPLYDTPYEPAENGGDSDPEHPRVPRESRLPQDDERP
PEEYDQPWEWKKERISKAFAVQFDGVDKSRMSPTKDGKARPLQRHSGGCLVNTKMSSLDH
CSPSLAERIDPSMPLESQFWYHGAISRTDAESLLRLCKEASYLVRNSETSKNDYSLSLKS
SQGFMHMKLSRTKENKYILGQNSCPFDSVPEIIHFYSSRKLPIKGAEHMSLLYPVAIRTL

>Gasterosteus aculeatus_SHF(ENSGACP_21857)
RSSALFAEIRSGGRGPKDGPARQLPLYDTPYEPAENGGDSDPEHPRCPRESRLPQDDERP
PEEYDQPWEWKKERISKAFAVQFDGVEKSRMSPTKEGKTRPLQRHSSGCLVNTKMSSLDH
GSSSLGERIDPSMPLESQFWYHGAISRTDAESLLRLCKEASYLVRNSETSKNDYSLSLKS
SQGFMHMKLSRTKESNYILGQNSGPFNSVPEIIHFYSSRKLPIKGAEHMSLLYPVAIKTL

>Oryzias latipes_SHF(ENSORLP_16372)
FEAFRLRKIRSGGRGSKEGSLRQLPLYDTPYEPSENGGDSDPELLRCPRESRLPQDDERP
PEEYDQPWEWKKERISKAFAVQFDGVDKPRMSPTKDGKGRPLQRHSSGCLVNTKMTSLDH
CSSPVGERIDPSMPLESQFWYHGAISRTDAESLLRLCKEASYLVRNSETSKNDYSLSLKS
SQGFMHMKLSRTKENKYILGQNSCPFDSVPDIIHFYSSRKLPIKGAEHMSLLYPVAIRTL

>Branchiostoma floridae_(XP_002589544)
MGHLLLEHQSPSYDVNINFPFAQTSKLMSCGLSHSSSTATHLGWRQVSSVLFQQPRFHARLLRDNPLFDR
RGIIVNGITIFKTYFMAYISVHSPVKSREDNVRRIDLVPRITTESPGHERTFPVCTVPNRKQVTRIMAKL
LKHLGLGVGKKPPPQPPRPDYYDQNSTKPRVGPRLSGGDSEDDNYADPADALPGNYSAVCEGGDARRKSS
GGDGGVGHHSTPTRTGSSKSDSSYSVSSTGSGSDGVIKRSAENIHSTPENTHVSKPMKPIVLDDYSDPYD
IRKAVLESRDYDVPPDCRPPKEDDFNNYSDPYDAQKIIQELRIQQSKEAKEETPRSSTPDSEGSSSDSAL
YEDPYEPSAPEDIDADTHQARLARELEKAKETQLKQQQQQQQQPDEDTRPAEDYDQPWEWSSKERLSQAF
AAQLDQQQPSPPPSTHTPPSADKRLAAVPESSASPLSKTRVFRKHSHEGSEPIDPSIPLEGQRWYHGSIS
RVDAENVLRSCRECSFLVRNSESSRTNFSLSIKMEDKECRDRGYFLVKTIATGKFGDIKLATAEDSLRLS
FKMRLLVLGFYGTPKHMQMSVYDFFNTIDRTYLVMEYCGMNGRLGEFIQQYRAGRGVGLAEKVVRHFTHQ
LVDGMKYVHKCGIVHRDLTVDNVLVGNRGRLRITGFYYATKLENGCELVSRNEPNFLEDRTKSGLEYTPP
EILCQEEYLGKPADVWGM

>Strongylocentrotus purpuratus_(XP_011680709)
MSKFLNKIFPGKKNASTRGEYLGGRPYDYCSNSLGDLTADNTPIQPASSLSSFHAGLSSASTSSTNQQYH
RNGPHDSHTSSDRYRHHSTEDDGAGVTDEFVFRGAGALNLVTNGNRRISDGGSGGDGLRRNEMGAEPRSP
TSKKPIVMDDYSDPKDVLKAVQESGMVIPPQKPEMVQPYPEDDYSVPYEAQRMIKMMRQSEEQKKGEEKK
KEGKKGSRHTDDPEGWSVPKGKERFKHHTYEEPPDVSPPIRRSETPDSYVGESSDELNGHSPASMSPSPH
RQVNYSKDHHSSSPMSSESADDTYPPMHSSSSQNHRQQTPQHDRRPTAEYDNPWEWSNMKMAKLGPSPEG
LEGPRGRSRSELPANRVMRTSPESDTRPGDEYDAPWEWMPMNRKLSQAITDKEKHHAGRISPLPETPTRG
AKKGNMKLDIKSRPVEMPGEPVDPNIPLTHQTWYHGKLSRSDAEKKLKLCVEGSYLVRQSESAARDYSLS
LKSAKGFMHMKIVFNHQSDGYILGEFSKPFPSISEMICYYTRQKLNIRGAEHMALLHPVIDQLL

>Drosophila melanogaster_(FBpp0305357)
MERMWRKVNHSLRNTSKSQAQQAAGGDGIIGGPATGATAATPQSTDTISSAGGFGDGQLV
VAVQGLASGGIGASITASGGSNATGRRLASSGGGGGCNKSLSQHVLQTRTASSERRRRRR
RKSRPRRGGGMGVTSCVGDPGGDNMSSSGGFYTLKEHQHYRPSHHHGGGVSVGVGGGSSR
RLFATSAPSGTVMMYPNPQRGTALAPSVGSGTGHANTAGLGGGGGGGAGGAGGGATGSGT
GGQPDISLRQRAVAKLRMFNFHLNWDLHMTHCKPCGPRLSGSGGNIITRRLCRNRRREDN
ELYRSNSFKFERFERKECLEELSNTLQKQIAICDDYSLPVDFVKKRPSSFDPCLAEAIPA
NPEHWIAPSPQTEFLPFGEAQQALQLQPAAAAATAAATTSAAAAANATAAAPQLPPPLPV
PVATLPNQAATAAAAATAAILATHQQQQQQQHQHLSNNNNNGGSTHGQQHTHSNNNNTLP
VGAQQQQQQQHQQQRATLQHPPLPNSNIKQASVKLIEGYSDPKDTRNHKKVYHKKAKKRS
TTGHKRHQQQQQQQQPHQQQLQQQQQQTLPTPRSAQQQQQLQQKLQQRHSTYNNNNGNSR
KDKRNSQYNSDSSAPKSSDDEADIDEEVEQQPLPVPQAPVQSASQPAAGLNSPDSISDDL
VRPLPPQLQRSPRKLTVAPAEHNKRQPSPYYYSDLLKSRDKDKDKDKDKDKDKDKDKDKD
KDKDKERDKDREDFKLKCRQSTASEPPQQTQTQLGGYRKSSSLDVPPAEEQPEAESHEEE
DPRTGQDSQSTPKRYSFTEEGVHIIRCETPSTSTSEESDCSECLKRREWHARALALVRKT
CNVQPRNQNPTGSELQLQLQHCDAGEGELLKCCPPPPAPAENQSQVQPMPPHRLLGPAAV
CGACITSAPASSLAGGRGSELGDDLEEEYFRPRSIFYVHPHGVHECIECAQPAQPATVPA
PTLSNPSLDIYGDDEDEVDGDEDEDEEDDSEDIMGSRRRQIYETAFDCKIAKSDDDLDEV
DRITNCSVLLQLSNGNGGDISKVTGSSKTRAECKRAKNSKNQALQEQTGEAHVQVHHVEA
ELGKLQLSQVDQQNQNQNQSQNQQHGVSATGSGASASSTQQLPVRGYTPSPPSTAPLPMK
FPGKHDRYLNMNSIRSAPNLPAANPAHPRLRDLRLPIQSMRHQCGGSSNDNSLTDSAYVN
PPSTNSNSNAASASASASVSATGSAAPRRPRSFVLESGRVLELRRSAQGHQGGQSTHHHH
HHHHHAPGSRRNRHGQSQGQTTGGGHNYSSTESIATSSSGGSMESLRSSTSEGNRSTSSS
ESRHSSSLSSHSSESGSGGSGGSGGSSVAYPLRPAPLLLHSKLHILSPISDKSSQEPASA
SASEQSQQPSQQLAPMASQEDDSTTSGAPAGNQVQVNASLKQPRSNRGAPNKALLQLADE
LLGSDSGISLHSREDGKPQALALQRLTLPKLQLIGAEGTTTSATASGAGGSSATGGSSGA
GGSGSGSVVASGSTGIQQDLRDLPFDMPKLRRRKTLQQEAACTSGSATSVDLGELPFDMP
KLRRRLRANQAEINNLLMHSTESSGISQASSSHSMRDDQKMSSKLDTALFRQNLTLNLNE
SRQATKQFGSLDLRGLNSNKELNMNLSQGYVTAVDLIDVTIPLERQGWYHGAITRIEAET
TLRPLSEGSFLVRNCESTKQDYSLSLKGAKGFMHMRIQRNETGQYILGQFSRPFETVPEM
IRHFCLNRLPVRGAEHMCLIEPVIAQLL

>Apis mellifera_(XP_006561304)
MERVWRRVQGAGRRSATARCGCPVQPCQLHVDQRAKRGGGRKSRGGPQTIVCSCQVQPCPVHPVLIRVRR
TRPGVGNCDCPPESQPCPHVARTSAVRRIRRCDCPERPCRHSAAGGGTRHRVSVQPSSPTFSQASQSNQQ
QQQQQQQQPCECAERINCTHTGGGGECECGEEAKPCSHTVRQRRSRRTCDCSGSGSQPCSHKPQHEGRIK
RVKCRVRRAGCAMARCTAELAMLHLHWGLATECAPCRPRALTRRLCRRQQSDNELYRSNSFKFERFERSK
DECATPLRKQVSLCDDYSLPVDFVNKRRPASAAAATSTVQWALPSPTVENAEVEVVEQYSDPKDSKNKAY
VEPGAETSLPTIYSKVNRNYCRPYTDPSASGSSCEDDEESRQVDIRKRKNSLYASTSTRAPSIDREKELS
SAEGALVDCVALVHLTDQSPTESNQPVRHPSPYYYGDLFKVPEQISKSQPNRYRKSVSLDVPGERSRTPG
IPKRNSVAGDGGSYSSQQQQPQQQQQSQQPLHYQQQQQQQLQLQQHQLQQHYQSQDLVSPTSGSEHAVPA
RSEILSSCIITEWDHTLMPPHRLLSHDLPTTVCTCVASAEEEEDELDQRQPQLTRHQVRKLRRTRRIDPQ
PILVEDEDDVEGEDEGEEEEEEDVEVEEDEEEMARQRHLYETAFDCKVNRSDDDLDDLDRVTNHPVLHSQ
IRSSSAIPVSRTSSSTDTSKQQQQQQAPYAGQSHSNKDRRKVVLLRPKPIPSRLQQQQQQQQQQSDNIST
LSQDIESLQINSSDEKTGSPRLPARGYTPSPPSTAPLPAKFHGNRDHLLLNIRSTPNLPSQPDHPRLKDL
RLPVKSSLRAKDSPQSSEGSILEIKSRPKSFAQETVESSQGRRFDKELILEFKGRPREDRQRPRSLIRES
KPIMEFKGRPHEAESDLLRPRRDVGLLEFKLRTSRRRPGYSSTESMATSSSGGSMESLRSSTSEGNRSTS
SSESRHSTSLSSHSSDSGGTNCYHHHQQPSMTGFLTHHANKLHILSPISDKSSQEPASETSDNNRNNNSQ
KASPEENVTTENNVTATNNVTNTNTTGNTNSVTSPMDTSFKKRRTPQNKNLINLALQSSSSGDAEIQGSD
SGISIESRAGIKCKPFGFHLLKPQLDNINLVDNEPELSDLPFDMPKLRRRRLLMQQDATTSGSATSVDLR
DLPFDMPKLKRRLRCMQSTESSGSQASSSLSVRDVEPPALFGGGLARPKMTLNLDAGNGTGNGGNSGQLP
PKKPGGLSLGLPLEINTARGSADLVDVGLPLERQGWYHGSITRIEAEAVLRLLREGSYLVRNSESTKQDY
SLSLKSARGFMHMRIQKNEELNAYILGQFSKPFDSIPEMVRHFSVNRLPIRGAEHMCLLHPVIAQLL

>Caenorhabditis elegans_(Y87G2A)
MMMTMAADYGSSEGHYDTPWEFLARPNSVRFSTADVRLSTSAAGDAKVSPHGSPSLCSSS
SFVNQLVQIGNSAVDARRKVPRDESKRRRPSDSEIYMEQNMNRVEAEKRLENRNLGDYLL
RSRGEGSAALSLRATKGVVHIKIEWNGEKWVIGEGPLFRSISSAISFYRRHPLPIRGADH
LVLKNQLKPV

>Nematostella vectensis_(XP_001635407)
MSKKSNKLSRTFPGRVKNETKSRQPLPSGFKRFADFLTLRRKKRKGDSAARQLEKSPWFHGKITAEYAEM
LMRGAGEFLVREDPAMPGMYFIAVRNKEQETLHLAITKVNHSKGTRIKYRVEDSDYMFDGIPELIQFYIS
ERRPVSIRPPAVLTIAISKESALLKEEDFRGRTSTAGSARIHRTTRGRLERKRSDPVLSTRVPSRVFNIE
ADDDSSASVPDKDRPHSRSNPPSIYYDDKQKTAEGGELFSSATTQSLEDVLDPPQIERRRHLSSSGSAPS
LYRKRDSGEGPESTYDSPRSIAIPTTTLKHVSPYGRQGRKRSQESGPVQALKSKEGVPLKDYATPSSLPV
NGSSNSQDELDYDVPRPSSMVTDKNNDDTNSKRDSGVTRESSTERDRAGSGVTECAKPRQTRQEIYQSVL
QKLRDKIVRPFLEQSCVTLARYMTKVDLDVVWTSHMGEGEGEPEGVAEGLELLILPQGRDIRSALIERYT
NLTYWVGALVVAAGDLGPRTQVVTKLIELADVLSDKHGNLVSFMAVLEGLALPQVTRLHHTWSCLHHQYS
SSAIMYHSTLKPLAGLLSSGAPSPFPGVCLPYVVPLAKLLEMTTEDALGGWGQDDVVQGIETLLAHLDAG
RTLIQQLDAYKDEYLKRSHETIPEDELKIMDYFRSRVNVGDVLGLGSDAHVRTQKLVTLLNWLSENAERA
SKPSADIWQATNAMAISIVCKPFDFFAIMKSGRLKGQIGRMNRGANLSAKIRLFSLHLKFPTDEKFTISR
VCPGMTVKDLKNRIELETGVPRHLLRLRYLDGYDLTDDRRLSYYNMVPAATVQVLLWPEWVSLVTAACKG
DYYGNQIGVFNFFRGVLASQIRTPAKLGQNTPREFNEKALVALYIASHRGHVNVVSRLVESGVYPCTKLP
SGRSPLHAAVNRKQITCVSILIGELYIDRVILSSAGRD